diff --git a/DEPS.bzl b/DEPS.bzl
index ea702b7fdfd55..d23b87c2e67f9 100644
--- a/DEPS.bzl
+++ b/DEPS.bzl
@@ -7145,13 +7145,13 @@ def go_deps():
         name = "com_github_tikv_client_go_v2",
         build_file_proto_mode = "disable_global",
         importpath = "github.com/tikv/client-go/v2",
-        sha256 = "9e86def6bedefa6095b20a2d90afa099ca301d49f6792eccb54883201df3063b",
-        strip_prefix = "github.com/tikv/client-go/v2@v2.0.8-0.20240316105842-98a7df8f413d",
+        sha256 = "1838f5b1e46ccef68f651efd1a01a2b70037062ba6a08d58b2bd6aa8d3580e0c",
+        strip_prefix = "github.com/tikv/client-go/v2@v2.0.8-0.20240318065517-a9128e8200ab",
         urls = [
-            "http://bazel-cache.pingcap.net:8080/gomod/github.com/tikv/client-go/v2/com_github_tikv_client_go_v2-v2.0.8-0.20240316105842-98a7df8f413d.zip",
-            "http://ats.apps.svc/gomod/github.com/tikv/client-go/v2/com_github_tikv_client_go_v2-v2.0.8-0.20240316105842-98a7df8f413d.zip",
-            "https://cache.hawkingrei.com/gomod/github.com/tikv/client-go/v2/com_github_tikv_client_go_v2-v2.0.8-0.20240316105842-98a7df8f413d.zip",
-            "https://storage.googleapis.com/pingcapmirror/gomod/github.com/tikv/client-go/v2/com_github_tikv_client_go_v2-v2.0.8-0.20240316105842-98a7df8f413d.zip",
+            "http://bazel-cache.pingcap.net:8080/gomod/github.com/tikv/client-go/v2/com_github_tikv_client_go_v2-v2.0.8-0.20240318065517-a9128e8200ab.zip",
+            "http://ats.apps.svc/gomod/github.com/tikv/client-go/v2/com_github_tikv_client_go_v2-v2.0.8-0.20240318065517-a9128e8200ab.zip",
+            "https://cache.hawkingrei.com/gomod/github.com/tikv/client-go/v2/com_github_tikv_client_go_v2-v2.0.8-0.20240318065517-a9128e8200ab.zip",
+            "https://storage.googleapis.com/pingcapmirror/gomod/github.com/tikv/client-go/v2/com_github_tikv_client_go_v2-v2.0.8-0.20240318065517-a9128e8200ab.zip",
         ],
     )
     go_repository(
diff --git a/go.mod b/go.mod
index 8fc203642b8a5..43a9a088d523a 100644
--- a/go.mod
+++ b/go.mod
@@ -107,7 +107,7 @@ require (
 	github.com/tdakkota/asciicheck v0.2.0
 	github.com/tiancaiamao/appdash v0.0.0-20181126055449-889f96f722a2
 	github.com/tidwall/btree v1.7.0
-	github.com/tikv/client-go/v2 v2.0.8-0.20240316105842-98a7df8f413d
+	github.com/tikv/client-go/v2 v2.0.8-0.20240318065517-a9128e8200ab
 	github.com/tikv/pd/client v0.0.0-20240229065730-92a31c12238e
 	github.com/timakin/bodyclose v0.0.0-20240125160201-f835fa56326a
 	github.com/twmb/murmur3 v1.1.6
diff --git a/go.sum b/go.sum
index 412d863583a2e..add08b72d29f0 100644
--- a/go.sum
+++ b/go.sum
@@ -869,8 +869,8 @@ github.com/tiancaiamao/gp v0.0.0-20221230034425-4025bc8a4d4a h1:J/YdBZ46WKpXsxsW
 github.com/tiancaiamao/gp v0.0.0-20221230034425-4025bc8a4d4a/go.mod h1:h4xBhSNtOeEosLJ4P7JyKXX7Cabg7AVkWCK5gV2vOrM=
 github.com/tidwall/btree v1.7.0 h1:L1fkJH/AuEh5zBnnBbmTwQ5Lt+bRJ5A8EWecslvo9iI=
 github.com/tidwall/btree v1.7.0/go.mod h1:twD9XRA5jj9VUQGELzDO4HPQTNJsoWWfYEL+EUQ2cKY=
-github.com/tikv/client-go/v2 v2.0.8-0.20240316105842-98a7df8f413d h1:QDsglttywjxGkxf7pjInpKTudLwy3qr/sR9BCxBiLow=
-github.com/tikv/client-go/v2 v2.0.8-0.20240316105842-98a7df8f413d/go.mod h1:9s6+YbGt0kW+9qTFDXuc5TkIpwpEf038S1UCa3utsSQ=
+github.com/tikv/client-go/v2 v2.0.8-0.20240318065517-a9128e8200ab h1:uzd6N2FtE/9d9g0x6QS2O48+Waxy4qjlyMbwk/vSZRQ=
+github.com/tikv/client-go/v2 v2.0.8-0.20240318065517-a9128e8200ab/go.mod h1:9s6+YbGt0kW+9qTFDXuc5TkIpwpEf038S1UCa3utsSQ=
 github.com/tikv/pd/client v0.0.0-20240229065730-92a31c12238e h1:kHXMmskVCNyH53u43I73Y5cmZ6yqqder/jGOiI7ylxs=
 github.com/tikv/pd/client v0.0.0-20240229065730-92a31c12238e/go.mod h1:Z/QAgOt29zvwBTd0H6pdx45VO6KRNc/O/DzGkVmSyZg=
 github.com/timakin/bodyclose v0.0.0-20240125160201-f835fa56326a h1:A6uKudFIfAEpoPdaal3aSqGxBzLyU8TqyXImLwo6dIo=
diff --git a/pkg/executor/insert.go b/pkg/executor/insert.go
index 28625264e65ee..8876180daf64d 100644
--- a/pkg/executor/insert.go
+++ b/pkg/executor/insert.go
@@ -88,14 +88,6 @@ func (e *InsertExec) exec(ctx context.Context, rows [][]types.Datum) error {
 	// If `ON DUPLICATE KEY UPDATE` is specified, and no `IGNORE` keyword,
 	// the to-be-insert rows will be check on duplicate keys and update to the new rows.
 	if len(e.OnDuplicate) > 0 {
-		if ignoreErr && txn.IsPipelined() {
-			// P-DML doesn't support staging now. In a INSERT IGNORE ... ON DUPLICATE ... stmt, it's
-			// possible that 1 row succeeded and 1 row returns error but is ignored, thus the whole
-			// statement can successfully commit. See TestIssue50043
-			// The second row is supposed to be cleanup by the staging mechanism, so forbid this
-			// case for P-DML temporarily.
-			return errors.New("cannot use pipelined mode with insert ignore and on duplicate update")
-		}
 		err := e.batchUpdateDupRows(ctx, rows)
 		if err != nil {
 			return err
diff --git a/pkg/executor/test/executor/executor_test.go b/pkg/executor/test/executor/executor_test.go
index be76b5b487a89..5d499f251819b 100644
--- a/pkg/executor/test/executor/executor_test.go
+++ b/pkg/executor/test/executor/executor_test.go
@@ -2797,8 +2797,17 @@ func TestIssue38756(t *testing.T) {
 }
 
 func TestIssue50043(t *testing.T) {
+	testIssue50043WithInitSQL(t, "")
+}
+
+func TestIssue50043WithPipelinedDML(t *testing.T) {
+	testIssue50043WithInitSQL(t, "set @@tidb_dml_type=bulk")
+}
+
+func testIssue50043WithInitSQL(t *testing.T, initSQL string) {
 	store := testkit.CreateMockStore(t)
 	tk := testkit.NewTestKit(t, store)
+	tk.MustExec(initSQL)
 	// Test simplified case by update.
 	tk.MustExec("use test")
 	tk.MustExec("create table t (c1 boolean ,c2 decimal ( 37 , 17 ), unique key idx1 (c1 ,c2),unique key idx2 ( c1 ));")
diff --git a/pkg/session/txn.go b/pkg/session/txn.go
index fbf7920a941bd..7f44220780fc6 100644
--- a/pkg/session/txn.go
+++ b/pkg/session/txn.go
@@ -113,7 +113,9 @@ func (txn *LazyTxn) initStmtBuf() {
 	}
 	buf := txn.Transaction.GetMemBuffer()
 	txn.initCnt = buf.Len()
-	txn.stagingHandle = buf.Staging()
+	if !txn.IsPipelined() {
+		txn.stagingHandle = buf.Staging()
+	}
 }
 
 // countHint is estimated count of mutations.
@@ -139,7 +141,9 @@ func (txn *LazyTxn) flushStmtBuf() {
 		}
 	}
 
-	buf.Release(txn.stagingHandle)
+	if !txn.IsPipelined() {
+		buf.Release(txn.stagingHandle)
+	}
 	txn.initCnt = buf.Len()
 }
 
@@ -148,7 +152,9 @@ func (txn *LazyTxn) cleanupStmtBuf() {
 		return
 	}
 	buf := txn.Transaction.GetMemBuffer()
-	buf.Cleanup(txn.stagingHandle)
+	if !txn.IsPipelined() {
+		buf.Cleanup(txn.stagingHandle)
+	}
 	txn.initCnt = buf.Len()
 
 	txn.mu.Lock()
@@ -320,7 +326,7 @@ func (txn *LazyTxn) changePendingToValid(ctx context.Context, sctx sessionctx.Co
 }
 
 func (txn *LazyTxn) changeToInvalid() {
-	if txn.stagingHandle != kv.InvalidStagingHandle {
+	if txn.stagingHandle != kv.InvalidStagingHandle && !txn.IsPipelined() {
 		txn.Transaction.GetMemBuffer().Cleanup(txn.stagingHandle)
 	}
 	txn.stagingHandle = kv.InvalidStagingHandle
diff --git a/pkg/store/driver/txn/unionstore_driver.go b/pkg/store/driver/txn/unionstore_driver.go
index 400bca8d921af..c6043be69a60a 100644
--- a/pkg/store/driver/txn/unionstore_driver.go
+++ b/pkg/store/driver/txn/unionstore_driver.go
@@ -68,24 +68,14 @@ func (m *memBuffer) GetFlags(key kv.Key) (kv.KeyFlags, error) {
 }
 
 func (m *memBuffer) Staging() kv.StagingHandle {
-	if m.isPipelinedDML {
-		// 0 stands for staging not supported.
-		return 0
-	}
 	return kv.StagingHandle(m.MemBuffer.Staging())
 }
 
 func (m *memBuffer) Cleanup(h kv.StagingHandle) {
-	if m.isPipelinedDML {
-		return
-	}
 	m.MemBuffer.Cleanup(int(h))
 }
 
 func (m *memBuffer) Release(h kv.StagingHandle) {
-	if m.isPipelinedDML {
-		return
-	}
 	m.MemBuffer.Release(int(h))
 }
 
diff --git a/pkg/table/tables/mutation_checker.go b/pkg/table/tables/mutation_checker.go
index 3ef2c42730b1e..ad47a1dfc565d 100644
--- a/pkg/table/tables/mutation_checker.go
+++ b/pkg/table/tables/mutation_checker.go
@@ -83,6 +83,9 @@ func CheckDataConsistency(
 	if t.Meta().GetPartitionInfo() != nil {
 		return nil
 	}
+	if txn.IsPipelined() {
+		return nil
+	}
 	if sh == 0 {
 		// some implementations of MemBuffer doesn't support staging, e.g. that in br/pkg/lightning/backend/kv
 		return nil
diff --git a/tests/realtikvtest/pipelineddmltest/pipelineddml_test.go b/tests/realtikvtest/pipelineddmltest/pipelineddml_test.go
index b5c7a60936dc1..bd3b51789d6d2 100644
--- a/tests/realtikvtest/pipelineddmltest/pipelineddml_test.go
+++ b/tests/realtikvtest/pipelineddmltest/pipelineddml_test.go
@@ -702,9 +702,9 @@ func TestInsertIgnoreOnDuplicateKeyUpdate(t *testing.T) {
 	tk.MustExec("drop table if exists t1")
 	tk.MustExec("create table t1(a int, b int, unique index u1(a, b), unique index u2(a))")
 	tk.MustExec("insert into t1 values(0, 0), (1, 1)")
-	tk.MustExecToErr("insert ignore into t1 values (0, 2) ,(1, 3) on duplicate key update b = 5, a = 0")
+	tk.MustExec("insert ignore into t1 values (0, 2) ,(1, 3) on duplicate key update b = 5, a = 0")
 	// if the statement execute successful, the following check should pass.
-	// tk.MustQuery("select * from t1").Sort().Check(testkit.Rows("0 5", "1 1"))
+	tk.MustQuery("select * from t1").Sort().Check(testkit.Rows("0 5", "1 1"))
 }
 
 func TestConflictError(t *testing.T) {