diff --git a/src/Analyser/NodeScopeResolver.php b/src/Analyser/NodeScopeResolver.php
index 991646c768..d562027865 100644
--- a/src/Analyser/NodeScopeResolver.php
+++ b/src/Analyser/NodeScopeResolver.php
@@ -343,6 +343,7 @@ private function processStmtNode(
 		} elseif (
 			!$stmt instanceof Static_
 			&& !$stmt instanceof Foreach_
+			&& !$stmt instanceof Node\Stmt\Global_
 		) {
 			$scope = $this->processStmtVarAnnotation($scope, $stmt, null);
 		}
@@ -1152,6 +1153,7 @@ private function processStmtNode(
 			}
 		} elseif ($stmt instanceof Node\Stmt\Global_) {
 			$hasYield = false;
+			$vars = [];
 			foreach ($stmt->vars as $var) {
 				if (!$var instanceof Variable) {
 					throw new \PHPStan\ShouldNotHappenException();
@@ -1165,6 +1167,11 @@ private function processStmtNode(
 				}
 
 				$scope = $scope->assignVariable($var->name, new MixedType());
+				$vars[] = $var->name;
+			}
+			$comment = CommentHelper::getDocComment($stmt);
+			if ($comment !== null) {
+				$scope = $this->processVarAnnotation($scope, $vars, $comment);
 			}
 		} elseif ($stmt instanceof Static_) {
 			$hasYield = false;
diff --git a/src/Rules/PhpDoc/WrongVariableNameInVarTagRule.php b/src/Rules/PhpDoc/WrongVariableNameInVarTagRule.php
index 418f10b5ba..77e332f5ad 100644
--- a/src/Rules/PhpDoc/WrongVariableNameInVarTagRule.php
+++ b/src/Rules/PhpDoc/WrongVariableNameInVarTagRule.php
@@ -73,6 +73,10 @@ public function processNode(Node $node, Scope $scope): array
 			return $this->processStmt($scope, $varTags, $node->expr);
 		}
 
+		if ($node instanceof Node\Stmt\Global_) {
+			return $this->processGlobal($scope, $node, $varTags);
+		}
+
 		return $this->processStmt($scope, $varTags, null);
 	}
 
@@ -285,4 +289,52 @@ private function processStmt(Scope $scope, array $varTags, ?Expr $defaultExpr):
 		return $errors;
 	}
 
+	/**
+	 * @param \PHPStan\Analyser\Scope $scope
+	 * @param \PHPStan\PhpDoc\Tag\VarTag[] $varTags
+	 * @return \PHPStan\Rules\RuleError[]
+	 */
+	private function processGlobal(Scope $scope, Node\Stmt\Global_ $node, array $varTags): array
+	{
+		$variableNames = [];
+		foreach ($node->vars as $var) {
+			if (!$var instanceof Expr\Variable) {
+				continue;
+			}
+			if (!is_string($var->name)) {
+				continue;
+			}
+
+			$variableNames[$var->name] = true;
+		}
+
+		$errors = [];
+		foreach (array_keys($varTags) as $name) {
+			if (is_int($name)) {
+				if (count($variableNames) === 1) {
+					continue;
+				}
+
+				$errors[] = RuleErrorBuilder::message(
+					'PHPDoc tag @var above multiple global variables does not specify variable name.'
+				)->build();
+				continue;
+			}
+
+			if (isset($variableNames[$name])) {
+				continue;
+			}
+
+			$errors[] = RuleErrorBuilder::message(sprintf(
+				'Variable $%s in PHPDoc tag @var does not match any global variable: %s',
+				$name,
+				implode(', ', array_map(static function (string $name): string {
+					return sprintf('$%s', $name);
+				}, array_keys($variableNames)))
+			))->build();
+		}
+
+		return $errors;
+	}
+
 }
diff --git a/tests/PHPStan/Analyser/NodeScopeResolverTest.php b/tests/PHPStan/Analyser/NodeScopeResolverTest.php
index aca1eeba3e..4a9ac97417 100644
--- a/tests/PHPStan/Analyser/NodeScopeResolverTest.php
+++ b/tests/PHPStan/Analyser/NodeScopeResolverTest.php
@@ -10753,6 +10753,11 @@ public function dataCompact(): array
 		return $this->gatherAssertTypes(__DIR__ . '/data/compact.php');
 	}
 
+	public function dataBug4500(): array
+	{
+		return $this->gatherAssertTypes(__DIR__ . '/data/bug-4500.php');
+	}
+
 	/**
 	 * @param string $file
 	 * @return array<string, mixed[]>
@@ -10966,6 +10971,7 @@ private function gatherAssertTypes(string $file): array
 	 * @dataProvider dataBug4398
 	 * @dataProvider dataBug4415
 	 * @dataProvider dataCompact
+	 * @dataProvider dataBug4500
 	 * @param string $assertType
 	 * @param string $file
 	 * @param mixed ...$args
diff --git a/tests/PHPStan/Analyser/data/bug-4500.php b/tests/PHPStan/Analyser/data/bug-4500.php
new file mode 100644
index 0000000000..7a928b5eef
--- /dev/null
+++ b/tests/PHPStan/Analyser/data/bug-4500.php
@@ -0,0 +1,74 @@
+<?php
+
+namespace Bug4500TypeInference;
+
+use function PHPStan\Analyser\assertType;
+
+class Foo
+{
+
+	public function doFirst(): void
+	{
+		global $foo;
+		assertType('mixed', $foo);
+	}
+
+	public function doFoo(): void
+	{
+		/** @var int */
+		global $foo;
+		assertType('int', $foo);
+	}
+
+	public function doBar(): void
+	{
+		/** @var int $foo */
+		global $foo;
+		assertType('int', $foo);
+	}
+
+	public function doBaz(): void
+	{
+		/** @var int */
+		global $foo, $bar;
+		assertType('mixed', $foo);
+		assertType('mixed', $bar);
+	}
+
+	public function doLorem(): void
+	{
+		/** @var int $foo */
+		global $foo, $bar;
+		assertType('int', $foo);
+		assertType('mixed', $bar);
+
+		$baz = 'foo';
+
+		/** @var int $baz */
+		global $lorem;
+		assertType('mixed', $lorem);
+		assertType('\'foo\'', $baz);
+	}
+
+	public function doIpsum(): void
+	{
+		/**
+		 * @var int $foo
+		 * @var string $bar
+		 */
+		global $foo, $bar;
+
+		assertType('int', $foo);
+		assertType('string', $bar);
+	}
+
+	public function doDolor(): void
+	{
+		/** @var int $baz */
+		global $lorem;
+
+		assertType('mixed', $lorem);
+		assertType('*ERROR*', $baz);
+	}
+
+}
diff --git a/tests/PHPStan/Rules/PhpDoc/WrongVariableNameInVarTagRuleTest.php b/tests/PHPStan/Rules/PhpDoc/WrongVariableNameInVarTagRuleTest.php
index 4f31c76926..f1992c5d8c 100644
--- a/tests/PHPStan/Rules/PhpDoc/WrongVariableNameInVarTagRuleTest.php
+++ b/tests/PHPStan/Rules/PhpDoc/WrongVariableNameInVarTagRuleTest.php
@@ -109,4 +109,22 @@ public function testBug3515(): void
 		$this->analyse([__DIR__ . '/data/bug-3515.php'], []);
 	}
 
+	public function testBug4500(): void
+	{
+		$this->analyse([__DIR__ . '/data/bug-4500.php'], [
+			[
+				'PHPDoc tag @var above multiple global variables does not specify variable name.',
+				23,
+			],
+			[
+				'Variable $baz in PHPDoc tag @var does not match any global variable: $lorem',
+				43,
+			],
+			[
+				'Variable $baz in PHPDoc tag @var does not match any global variable: $lorem',
+				49,
+			],
+		]);
+	}
+
 }
diff --git a/tests/PHPStan/Rules/PhpDoc/data/bug-4500.php b/tests/PHPStan/Rules/PhpDoc/data/bug-4500.php
new file mode 100644
index 0000000000..bdf832d565
--- /dev/null
+++ b/tests/PHPStan/Rules/PhpDoc/data/bug-4500.php
@@ -0,0 +1,52 @@
+<?php
+
+namespace Bug4500;
+
+class Foo
+{
+
+	public function doFoo(): void
+	{
+		/** @var int */
+		global $foo;
+	}
+
+	public function doBar(): void
+	{
+		/** @var int $foo */
+		global $foo;
+	}
+
+	public function doBaz(): void
+	{
+		/** @var int */
+		global $foo, $bar;
+	}
+
+	public function doLorem(): void
+	{
+		/** @var int $foo */
+		global $foo, $bar;
+	}
+
+	public function doIpsum(): void
+	{
+		/**
+		 * @var int $foo
+		 * @var string $bar
+		 */
+		global $foo, $bar;
+
+		$baz = 'foo';
+
+		/** @var int $baz */
+		global $lorem;
+	}
+
+	public function doDolor(): void
+	{
+		/** @var int $baz */
+		global $lorem;
+	}
+
+}