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Adding expression input schema definition to repo #3368

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DSuveges opened this issue Jul 3, 2024 · 0 comments · May be fixed by opentargets/json_schema#212
Open

Adding expression input schema definition to repo #3368

DSuveges opened this issue Jul 3, 2024 · 0 comments · May be fixed by opentargets/json_schema#212
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@DSuveges
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DSuveges commented Jul 3, 2024

For helping communication with expression data providers (eg. PRIDE) the expected input schema should be added to JSON schema repo.

Adding the following schemas:

  • Aggregated data (eg. gs://atlas_baseline_expression/rel_40_2024-05-08/aggregated_data/E-CURD-25/E-CURD-25-expression-data-tpms.jsonl.bz2) [1].
  • Unaggregated data (eg. gs://atlas_baseline_expression/rel_40_2024-05-08/metadata/E-CURD-25/E-CURD-25.metadata.json) [2].
  • Study metadata (eg. gs://atlas_baseline_expression/rel_40_2024-05-08/unaggregated_data/E-CURD-25/E-CURD-25-unaggregated-expression-data-fpkms.jsonl.bz2) [3].

These schemas will serve as a common ground, also a way to get feedback and maybe adjusting.

[1] Aggregated data:

{
  "geneProductId": "ENSRNA049436185",
  "expression": [
    {
      "assayGroupId": "g1",
      "min": 0.0,
      "q1": 0.0,
      "q2": 0.0,
      "q3": 0.0,
      "max": 0.0
    },
    {
      "assayGroupId": "g2",
      "min": 0.0,
      "q1": 0.0,
      "q2": 0.0,
      "q3": 0.0,
      "max": 0.0
    },
    {
      "assayGroupId": "g3",
      "min": 0.0,
      "q1": 0.0,
      "q2": 0.0,
      "q3": 0.0,
      "max": 0.0
    },
    {
      "assayGroupId": "g4",
      "min": 0.0,
      "q1": 0.0,
      "q2": 0.0,
      "q3": 0.0,
      "max": 0.0
    }
  ],
  "unit": "tpms"
}

[2] Study metadata:

{
  "experimentId": "E-CURD-25",
  "experimentType": "rnaseq_mrna_baseline",
  "species": "Sorghum bicolor",
  "speciesOntURI": "http://purl.obolibrary.org/obo/NCBITaxon_4558",
  "pubmedIds": [
    "28186631"
  ],
  "provider": "Gina; Turco; Kaisa; Kajala; Govindarajan; Kunde-Ramamoorthy; Chew-Yee; Ngan; Andrew; Olson; Shweta; Deshphande; Barbara; Waring; Scott; Stelpflug; Patricia; Klein; Shawn; Kaeppler; Doreen; Ware; Chia-Lin; Wei; J; Etchells; Siobhan; Brady",
  "experimentalDesigns": [
    {
      "assayGroupId": "g1",
      "assayId": "SRR2102337",
      "assayGroup": "nonvascular system",
      "age": "3 day",
      "cultivar": "BTx623",
      "genotype": "wild type genotype",
      "organismPart": "nonvascular system"
    },
    {
      "assayGroupId": "g1",
      "assayId": "SRR2102338",
      "assayGroup": "nonvascular system",
      "age": "3 day",
      "cultivar": "BTx623",
      "genotype": "wild type genotype",
      "organismPart": "nonvascular system"
    },
    {
      "assayGroupId": "g1",
      "assayId": "SRR2102336",
      "assayGroup": "nonvascular system",
      "age": "3 day",
      "cultivar": "BTx623",
      "genotype": "wild type genotype",
      "organismPart": "nonvascular system"
    },
    {
      "assayGroupId": "g2",
      "assayId": "SRR2102328",
      "assayGroup": "root",
      "age": "3 day",
      "cultivar": "BTx623",
      "genotype": "wild type genotype",
      "organismPart": "root",
      "organismPartOntURI": "http://purl.obolibrary.org/obo/PO_0009005"
    },
    {
      "assayGroupId": "g2",
      "assayId": "SRR2102327",
      "assayGroup": "root",
      "age": "3 day",
      "cultivar": "BTx623",
      "genotype": "wild type genotype",
      "organismPart": "root",
      "organismPartOntURI": "http://purl.obolibrary.org/obo/PO_0009005"
    },
    {
      "assayGroupId": "g2",
      "assayId": "SRR2102329",
      "assayGroup": "root",
      "age": "3 day",
      "cultivar": "BTx623",
      "genotype": "wild type genotype",
      "organismPart": "root",
      "organismPartOntURI": "http://purl.obolibrary.org/obo/PO_0009005"
    },
    {
      "assayGroupId": "g3",
      "assayId": "SRR2102330",
      "assayGroup": "shoot",
      "age": "3 day",
      "cultivar": "BTx623",
      "genotype": "wild type genotype",
      "organismPart": "shoot",
      "organismPartOntURI": "http://purl.obolibrary.org/obo/PO_0009006"
    },
    {
      "assayGroupId": "g3",
      "assayId": "SRR2102331",
      "assayGroup": "shoot",
      "age": "3 day",
      "cultivar": "BTx623",
      "genotype": "wild type genotype",
      "organismPart": "shoot",
      "organismPartOntURI": "http://purl.obolibrary.org/obo/PO_0009006"
    },
    {
      "assayGroupId": "g3",
      "assayId": "SRR2102332",
      "assayGroup": "shoot",
      "age": "3 day",
      "cultivar": "BTx623",
      "genotype": "wild type genotype",
      "organismPart": "shoot",
      "organismPartOntURI": "http://purl.obolibrary.org/obo/PO_0009006"
    },
    {
      "assayGroupId": "g4",
      "assayId": "SRR2102335",
      "assayGroup": "vascular system",
      "age": "3 day",
      "cultivar": "BTx623",
      "genotype": "wild type genotype",
      "organismPart": "vascular system",
      "organismPartOntURI": "http://purl.obolibrary.org/obo/PO_0000034"
    },
    {
      "assayGroupId": "g4",
      "assayId": "SRR2102334",
      "assayGroup": "vascular system",
      "age": "3 day",
      "cultivar": "BTx623",
      "genotype": "wild type genotype",
      "organismPart": "vascular system",
      "organismPartOntURI": "http://purl.obolibrary.org/obo/PO_0000034"
    },
    {
      "assayGroupId": "g4",
      "assayId": "SRR2102333",
      "assayGroup": "vascular system",
      "age": "3 day",
      "cultivar": "BTx623",
      "genotype": "wild type genotype",
      "organismPart": "vascular system",
      "organismPartOntURI": "http://purl.obolibrary.org/obo/PO_0000034"
    }
  ]
}

[3] Unaggregated data:

{
  "geneProductId": "ENSRNA049436185",
  "unit": "fpkms",
  "expression": [
    {
      "assayId": "SRR2102331",
      "value": 0.0
    },
    {
      "assayId": "SRR2102328",
      "value": 0.0
    },
    {
      "assayId": "SRR2102329",
      "value": 0.0
    },
    {
      "assayId": "SRR2102332",
      "value": 0.0
    },
    {
      "assayId": "SRR2102336",
      "value": 0.0
    },
    {
      "assayId": "SRR2102338",
      "value": 0.0
    },
    {
      "assayId": "SRR2102335",
      "value": 0.0
    },
    {
      "assayId": "SRR2102337",
      "value": 0.0
    },
    {
      "assayId": "SRR2102330",
      "value": 0.0
    },
    {
      "assayId": "SRR2102333",
      "value": 0.0
    },
    {
      "assayId": "SRR2102334",
      "value": 0.0
    },
    {
      "assayId": "SRR2102327",
      "value": 0.0
    }
  ]
}
@DSuveges DSuveges self-assigned this Jul 3, 2024
@DSuveges DSuveges added Data Relates to Open Targets data team Platform Issues related to Open Targets Platform labels Jul 3, 2024
@Tobi1kenobi Tobi1kenobi self-assigned this Aug 19, 2024
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