diff --git a/opentelemetry-sdk/tests/metrics/test_periodic_exporting_metric_reader.py b/opentelemetry-sdk/tests/metrics/test_periodic_exporting_metric_reader.py
index ca7a1676308..4552a69063f 100644
--- a/opentelemetry-sdk/tests/metrics/test_periodic_exporting_metric_reader.py
+++ b/opentelemetry-sdk/tests/metrics/test_periodic_exporting_metric_reader.py
@@ -15,6 +15,8 @@
 import time
 from unittest.mock import Mock
 
+from flaky import flaky
+
 from opentelemetry.sdk._metrics.export import (
     MetricExporter,
     PeriodicExportingMetricReader,
@@ -99,13 +101,14 @@ def test_ticker_called(self):
         self.assertTrue(collect_mock.assert_called_once)
         pmr.shutdown()
 
+    @flaky(max_runs=3, min_passes=1)
     def test_ticker_collects_metrics(self):
         exporter = FakeMetricsExporter()
 
         pmr = self._create_periodic_reader(
             metrics_list, exporter, interval=100
         )
-        time.sleep(0.11)
+        time.sleep(0.15)
         self.assertEqual(exporter.metrics, metrics_list)
         pmr.shutdown()
 
diff --git a/tox.ini b/tox.ini
index 2999b7fe434..4f7e1004691 100644
--- a/tox.ini
+++ b/tox.ini
@@ -70,6 +70,7 @@ deps =
   -c dev-requirements.txt
   opentelemetry: pytest
   opentelemetry: pytest-benchmark
+  opentelemetry: flaky
   coverage: pytest
   coverage: pytest-cov
   mypy,mypyinstalled: mypy