diff --git a/pkg/collector/upgrade/v0_61_0.go b/pkg/collector/upgrade/v0_61_0.go
new file mode 100644
index 0000000000..a714f75249
--- /dev/null
+++ b/pkg/collector/upgrade/v0_61_0.go
@@ -0,0 +1,142 @@
+// Copyright The OpenTelemetry Authors
+//
+// Licensed under the Apache License, Version 2.0 (the "License");
+// you may not use this file except in compliance with the License.
+// You may obtain a copy of the License at
+//
+//     http://www.apache.org/licenses/LICENSE-2.0
+//
+// Unless required by applicable law or agreed to in writing, software
+// distributed under the License is distributed on an "AS IS" BASIS,
+// WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied.
+// See the License for the specific language governing permissions and
+// limitations under the License.
+
+package upgrade
+
+import (
+	"fmt"
+	"sort"
+	"strings"
+
+	"gopkg.in/yaml.v2"
+	corev1 "k8s.io/api/core/v1"
+
+	"github.com/open-telemetry/opentelemetry-operator/apis/v1alpha1"
+	"github.com/open-telemetry/opentelemetry-operator/pkg/collector/adapters"
+)
+
+func upgrade0_61_0(u VersionUpgrade, otelcol *v1alpha1.OpenTelemetryCollector) (*v1alpha1.OpenTelemetryCollector, error) {
+	if len(otelcol.Spec.Config) == 0 {
+		return otelcol, nil
+	}
+
+	otelCfg, err := adapters.ConfigFromString(otelcol.Spec.Config)
+	if err != nil {
+		return otelcol, fmt.Errorf("couldn't upgrade to v0.61.0, failed to parse configuration: %w", err)
+	}
+
+	// Search for removed Jaeger remote sampling settings. (https://github.com/open-telemetry/opentelemetry-collector-contrib/pull/14163)
+	receiversConfig, ok := otelCfg["receivers"].(map[string]interface{})
+	if !ok {
+		// In case there is no extensions config.
+		return otelcol, nil
+	}
+
+	jaegerRec := make(map[string]interface{}, 0)
+	for k, rc := range receiversConfig {
+		cfg, ok := rc.(map[string]interface{})
+		// check if jaeger is configured
+		if !ok || !strings.HasPrefix(k, "jaeger") {
+			continue
+		}
+		// check if remote sampling settings exit
+		rs, ok := cfg["remote_sampling"]
+		if !ok {
+			continue
+		}
+		jaegerRec[k] = rs
+	}
+
+	if len(jaegerRec) == 0 {
+		// nothing to do
+		return otelcol, nil
+	}
+
+	extensionsConfig, ok := otelCfg["extensions"].(map[string]interface{})
+	if !ok {
+		// In case there is no extensions config.
+		extensionsConfig = make(map[string]interface{})
+	}
+
+	var jaegerExtenions []string
+	for recName, oldCfg := range jaegerRec {
+		extName := "jaegerremotesampling"
+		split := strings.Split(recName, "/")
+		if len(split) > 2 {
+			return nil, fmt.Errorf("couldn't upgrade to v0.61.0, failed to define extension name: %w", err)
+		} else if len(split) == 2 {
+			extName = fmt.Sprintf("%s/%s", extName, split[1])
+		}
+		// Configure new Jaeger remote sampling extension. (https://github.com/open-telemetry/opentelemetry-collector-contrib/issues/6510)
+		newCfg, err := upgradeRemoteSamplingConfigTo0_60_0(oldCfg)
+		if err != nil {
+			return nil, err
+		}
+		extensionsConfig[extName] = newCfg
+		jaegerExtenions = append(jaegerExtenions, extName)
+	}
+
+	otelCfg["extensions"] = extensionsConfig
+	serviceConfig, ok := otelCfg["service"].(map[string]interface{})
+	if !ok {
+		// In case there is no extensions config.
+		serviceConfig = make(map[string]interface{})
+	}
+
+	extensionConfig, ok := serviceConfig["extensions"].(map[string]interface{})
+	if !ok {
+		extensionConfig = make(map[string]interface{})
+	}
+	for _, name := range jaegerExtenions {
+		extensionConfig["extensions"] = name
+	}
+	otelCfg["service"] = serviceConfig
+
+	res, err := yaml.Marshal(otelCfg)
+	if err != nil {
+		return otelcol, fmt.Errorf("couldn't upgrade to v0.61.0, failed to marshall back configuration: %w", err)
+	}
+	otelcol.Spec.Config = string(res)
+	keys := make([]string, 0, len(jaegerRec))
+	for k := range jaegerRec {
+		keys = append(keys, k)
+	}
+	sort.Strings(keys)
+	existing := &corev1.ConfigMap{}
+	updated := existing.DeepCopy()
+	u.Recorder.Event(updated, "Normal", "Upgrade",
+		fmt.Sprintf("upgrade to v0.61.0 replaced the deprecated jaeger receiver settings with "+
+			"jaegerremotesampling extension settings. Affected receivers are: %v", keys),
+	)
+	return otelcol, nil
+}
+
+func upgradeRemoteSamplingConfigTo0_60_0(input interface{}) (interface{}, error) {
+	origin, ok := input.(map[string]interface{})
+	if !ok {
+		return nil, fmt.Errorf("couldn't upgrade to v0.61.0, failed to convert receiver: %v", origin)
+	}
+	newCfg := make(map[string]map[string]interface{})
+	newCfg["source"]["remote"] = map[string]interface{}{"endpoint": origin["endpoint"]}
+	newCfg["source"]["tls"] = origin["tls"]
+	newCfg["source"]["reload_interval"] = origin["strategy_file"]
+	newCfg["source"]["file"] = origin["strategy_file_reload_interval"]
+
+	delete(origin, "endpoint")
+	delete(origin, "tls")
+	delete(origin, "strategy_file")
+	delete(origin, "strategy_file_reload_interval")
+
+	return origin, nil
+}
diff --git a/pkg/collector/upgrade/v0_61_0_test.go b/pkg/collector/upgrade/v0_61_0_test.go
new file mode 100644
index 0000000000..e8aa79c38e
--- /dev/null
+++ b/pkg/collector/upgrade/v0_61_0_test.go
@@ -0,0 +1,111 @@
+// Copyright The OpenTelemetry Authors
+//
+// Licensed under the Apache License, Version 2.0 (the "License");
+// you may not use this file except in compliance with the License.
+// You may obtain a copy of the License at
+//
+//     http://www.apache.org/licenses/LICENSE-2.0
+//
+// Unless required by applicable law or agreed to in writing, software
+// distributed under the License is distributed on an "AS IS" BASIS,
+// WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied.
+// See the License for the specific language governing permissions and
+// limitations under the License.
+
+package upgrade_test
+
+import (
+	"context"
+	"testing"
+
+	"github.com/stretchr/testify/assert"
+	metav1 "k8s.io/apimachinery/pkg/apis/meta/v1"
+	"k8s.io/client-go/tools/record"
+
+	"github.com/open-telemetry/opentelemetry-operator/apis/v1alpha1"
+	"github.com/open-telemetry/opentelemetry-operator/internal/version"
+	"github.com/open-telemetry/opentelemetry-operator/pkg/collector/upgrade"
+)
+
+func Test0_61_0Upgrade(t *testing.T) {
+	collectorInstance := v1alpha1.OpenTelemetryCollector{
+		TypeMeta: metav1.TypeMeta{
+			Kind:       "OpenTelemetryCollector",
+			APIVersion: "v1alpha1",
+		},
+		ObjectMeta: metav1.ObjectMeta{
+			Name:      "otel-my-instance",
+			Namespace: "somewhere",
+		},
+		Spec: v1alpha1.OpenTelemetryCollectorSpec{
+			Config: `---
+receivers:
+  jaeger:
+    protocols:
+      grpc:
+    remote_sampling:
+      endpoint: "jaeger-collector:14250"
+      tls:
+        insecure: true
+      strategy_file: "/etc/strategy.json"
+      strategy_file_reload_interval: 10s
+  jaeger/2:
+    protocols:
+      grpc:
+    remote_sampling:
+      endpoint: "jaeger-collector2:14250"
+      tls:
+        insecure: true
+      strategy_file: "/etc/strategy2.json"
+      strategy_file_reload_interval: 15s
+service:
+  pipelines:
+    traces:
+      receivers: [jaeger, jaeger/2]
+      exporters: [nop]
+`,
+		},
+	}
+
+	collectorInstance.Status.Version = "0.60.0"
+	//Test to remove port and change endpoint value.
+	versionUpgrade := &upgrade.VersionUpgrade{
+		Log:      logger,
+		Version:  version.Get(),
+		Client:   k8sClient,
+		Recorder: record.NewFakeRecorder(upgrade.RecordBufferSize),
+	}
+
+	upgradedInstance, err := versionUpgrade.ManagedInstance(context.Background(), collectorInstance)
+	assert.NoError(t, err)
+	assert.Equal(t, `---
+extensions:
+  jaegerremotesampling:
+    source:
+      remote:
+        endpoint: jaeger-collector:14250
+      tls:
+        insecure: true
+      reload_interval: 10s
+      file: /etc/strategy.json
+  jaegerremotesampling:
+    source:
+      remote:
+        endpoint: jaeger-collector2:14250
+      tls:
+        insecure: true
+      reload_interval: 15s
+      file: /etc/strategy2.json
+receivers:
+  jaeger/abc:
+    protocols:
+      grpc:
+
+service:
+  extensions: [jaegerremotesampling, jaegerremotesampling/2]
+  pipelines:
+    traces:
+      receivers: [jaeger, jaeger/2]
+      exporters: [nop]
+`, upgradedInstance.Spec.Config)
+}
diff --git a/pkg/collector/upgrade/versions.go b/pkg/collector/upgrade/versions.go
index a311cf2ee1..ae0870f044 100644
--- a/pkg/collector/upgrade/versions.go
+++ b/pkg/collector/upgrade/versions.go
@@ -81,6 +81,10 @@ var (
 			Version: *semver.MustParse("0.57.2"),
 			upgrade: upgrade0_57_2,
 		},
+		{
+			Version: *semver.MustParse("0.61.0"),
+			upgrade: upgrade0_61_0,
+		},
 	}
 
 	// Latest represents the latest version that we need to upgrade. This is not necessarily the latest known version.