diff --git a/experimental/CHANGELOG.md b/experimental/CHANGELOG.md
index 2d5ea268fa..98efacaa7e 100644
--- a/experimental/CHANGELOG.md
+++ b/experimental/CHANGELOG.md
@@ -6,6 +6,10 @@ All notable changes to experimental packages in this project will be documented
 
 ### :boom: Breaking Change
 
+* Add `resourceDetectors` option to `NodeSDK` [#3210](https://github.com/open-telemetry/opentelemetry-js/issues/3210)
+  * `NodeSDK.detectResources()` function is no longer able to receive config as a parameter.
+    Instead, the detectors are passed to the constructor.
+
 * chore(metrics-sdk): clean up exports [#3197](https://github.com/open-telemetry/opentelemetry-js/pull/3197) @pichlermarc
   * removes export for:
     * `AccumulationRecord`
@@ -18,6 +22,8 @@ All notable changes to experimental packages in this project will be documented
 
 ### :rocket: (Enhancement)
 
+* Add `resourceDetectors` option to `NodeSDK` [#3210](https://github.com/open-telemetry/opentelemetry-js/issues/3210)
+
 ### :bug: (Bug Fix)
 
 ### :books: (Refine Doc)
diff --git a/experimental/packages/opentelemetry-sdk-node/README.md b/experimental/packages/opentelemetry-sdk-node/README.md
index 5b288ba1f3..e0ed90099c 100644
--- a/experimental/packages/opentelemetry-sdk-node/README.md
+++ b/experimental/packages/opentelemetry-sdk-node/README.md
@@ -114,9 +114,14 @@ or configure each instrumentation individually.
 
 Configure a resource. Resources may also be detected by using the `autoDetectResources` method of the SDK.
 
+### resourceDetectors
+
+Configure resource detectors. By default, the resource detectors are [envDetector, processDetector].
+NOTE: In order to enable the detection, the parameter `autoDetectResources` has to be `true`.
+
 ### sampler
 
-Configure a custom sampler. By default all traces will be sampled.
+Configure a custom sampler. By default, all traces will be sampled.
 
 ### spanProcessor
 
diff --git a/experimental/packages/opentelemetry-sdk-node/src/sdk.ts b/experimental/packages/opentelemetry-sdk-node/src/sdk.ts
index 2c6005806d..11870ebf28 100644
--- a/experimental/packages/opentelemetry-sdk-node/src/sdk.ts
+++ b/experimental/packages/opentelemetry-sdk-node/src/sdk.ts
@@ -21,6 +21,7 @@ import {
   registerInstrumentations
 } from '@opentelemetry/instrumentation';
 import {
+  Detector,
   detectResources,
   envDetector,
   processDetector,
@@ -62,6 +63,7 @@ export class NodeSDK {
   private _instrumentations: InstrumentationOption[];
 
   private _resource: Resource;
+  private _resourceDetectors: Detector[];
 
   private _autoDetectResources: boolean;
 
@@ -74,6 +76,7 @@ export class NodeSDK {
    */
   public constructor(configuration: Partial<NodeSDKConfiguration> = {}) {
     this._resource = configuration.resource ?? new Resource({});
+    this._resourceDetectors = configuration.resourceDetectors ?? [envDetector, processDetector];
 
     this._serviceName = configuration.serviceName;
 
@@ -166,12 +169,9 @@ export class NodeSDK {
   }
 
   /** Detect resource attributes */
-  public async detectResources(
-    config?: ResourceDetectionConfig
-  ): Promise<void> {
+  public async detectResources(): Promise<void> {
     const internalConfig: ResourceDetectionConfig = {
-      detectors: [envDetector, processDetector],
-      ...config,
+      detectors: this._resourceDetectors,
     };
 
     this.addResource(await detectResources(internalConfig));
diff --git a/experimental/packages/opentelemetry-sdk-node/src/types.ts b/experimental/packages/opentelemetry-sdk-node/src/types.ts
index 425b375bac..722201f03f 100644
--- a/experimental/packages/opentelemetry-sdk-node/src/types.ts
+++ b/experimental/packages/opentelemetry-sdk-node/src/types.ts
@@ -17,7 +17,7 @@
 import type { ContextManager, SpanAttributes } from '@opentelemetry/api';
 import { TextMapPropagator } from '@opentelemetry/api';
 import { InstrumentationOption } from '@opentelemetry/instrumentation';
-import { Resource } from '@opentelemetry/resources';
+import { Detector, Resource } from '@opentelemetry/resources';
 import { MetricReader, View } from '@opentelemetry/sdk-metrics';
 import {
   Sampler,
@@ -35,6 +35,7 @@ export interface NodeSDKConfiguration {
   views: View[]
   instrumentations: InstrumentationOption[];
   resource: Resource;
+  resourceDetectors: Detector[];
   sampler: Sampler;
   serviceName?: string;
   spanProcessor: SpanProcessor;
diff --git a/experimental/packages/opentelemetry-sdk-node/test/sdk.test.ts b/experimental/packages/opentelemetry-sdk-node/test/sdk.test.ts
index edad60c5ec..ebc07dc2bc 100644
--- a/experimental/packages/opentelemetry-sdk-node/test/sdk.test.ts
+++ b/experimental/packages/opentelemetry-sdk-node/test/sdk.test.ts
@@ -41,7 +41,7 @@ import * as assert from 'assert';
 import * as semver from 'semver';
 import * as Sinon from 'sinon';
 import { NodeSDK } from '../src';
-import { envDetector, processDetector } from '@opentelemetry/resources';
+import {envDetector, processDetector, Resource} from '@opentelemetry/resources';
 
 
 const DefaultContextManager = semver.gte(process.version, '14.8.0')
@@ -284,19 +284,47 @@ describe('Node SDK', () => {
       delete process.env.OTEL_RESOURCE_ATTRIBUTES;
     });
 
-    describe('with a buggy detector', () => {
+    describe('with a custom resource', () => {
       it('returns a merged resource', async () => {
         const sdk = new NodeSDK({
           autoDetectResources: true,
+          resourceDetectors: [processDetector, {
+            async detect(): Promise<Resource> {
+              return new Resource({'customAttr': 'someValue'});
+            }
+          },
+          envDetector]
+        });
+        await sdk.detectResources();
+        const resource = sdk['_resource'];
+
+        assert.strictEqual(
+          resource.attributes['customAttr'],
+          'someValue'
+        );
+
+        assertServiceResource(resource, {
+          instanceId: '627cc493',
+          name: 'my-service',
+          namespace: 'default',
+          version: '0.0.1',
         });
-        await sdk.detectResources({
-          detectors: [processDetector, {
+      });
+    });
+
+    describe('with a buggy detector', () => {
+      it('returns a merged resource', async () => {
+        const sdk = new NodeSDK({
+          autoDetectResources: true,
+          resourceDetectors: [processDetector, {
             detect() {
               throw new Error('Buggy detector');
             }
           },
           envDetector]
         });
+
+        await sdk.detectResources();
         const resource = sdk['_resource'];
 
         assertServiceResource(resource, {