diff --git a/javaagent-tooling/src/main/java/io/opentelemetry/javaagent/tooling/ignore/GlobalIgnoredTypesConfigurer.java b/javaagent-tooling/src/main/java/io/opentelemetry/javaagent/tooling/ignore/GlobalIgnoredTypesConfigurer.java
index f654b9c76305..8247ba1b2d66 100644
--- a/javaagent-tooling/src/main/java/io/opentelemetry/javaagent/tooling/ignore/GlobalIgnoredTypesConfigurer.java
+++ b/javaagent-tooling/src/main/java/io/opentelemetry/javaagent/tooling/ignore/GlobalIgnoredTypesConfigurer.java
@@ -119,6 +119,8 @@ private static void configureIgnoredClassLoaders(IgnoredTypesBuilder builder) {
             "org.springframework.context.support.ContextTypeMatchClassLoader$ContextOverridingClassLoader")
         .ignoreClassLoader("sun.misc.Launcher$ExtClassLoader")
         .ignoreClassLoader("org.openjdk.nashorn.internal.runtime.ScriptLoader")
+        .ignoreClassLoader("org.codehaus.janino.ByteArrayClassLoader")
+        .ignoreClassLoader("org.eclipse.persistence.internal.jaxb.JaxbClassLoader")
         .ignoreClassLoader(AgentClassLoader.class.getName())
         .ignoreClassLoader(ExtensionClassLoader.class.getName());