diff --git a/instrumentation/grpc-1.6/library/src/main/java/io/opentelemetry/instrumentation/grpc/v1_6/TracingClientInterceptor.java b/instrumentation/grpc-1.6/library/src/main/java/io/opentelemetry/instrumentation/grpc/v1_6/TracingClientInterceptor.java
index c2ee83b329b3..9244eb879822 100644
--- a/instrumentation/grpc-1.6/library/src/main/java/io/opentelemetry/instrumentation/grpc/v1_6/TracingClientInterceptor.java
+++ b/instrumentation/grpc-1.6/library/src/main/java/io/opentelemetry/instrumentation/grpc/v1_6/TracingClientInterceptor.java
@@ -52,7 +52,7 @@ public <REQUEST, RESPONSE> ClientCall<REQUEST, RESPONSE> interceptCall(
         // call other interceptors
         result = next.newCall(method, callOptions);
       } catch (Throwable e) {
-        instrumenter.end(context, request, null, e);
+        instrumenter.end(context, request, Status.UNKNOWN, e);
         throw e;
       }
     }
@@ -100,7 +100,7 @@ public void start(Listener<RESPONSE> responseListener, Metadata headers) {
             new TracingClientCallListener(responseListener, parentContext, context, request),
             headers);
       } catch (Throwable e) {
-        instrumenter.end(context, request, null, e);
+        instrumenter.end(context, request, Status.UNKNOWN, e);
         throw e;
       }
     }
@@ -110,7 +110,7 @@ public void sendMessage(REQUEST message) {
       try (Scope ignored = context.makeCurrent()) {
         super.sendMessage(message);
       } catch (Throwable e) {
-        instrumenter.end(context, request, null, e);
+        instrumenter.end(context, request, Status.UNKNOWN, e);
         throw e;
       }
       Span span = Span.fromContext(context);
diff --git a/instrumentation/grpc-1.6/library/src/main/java/io/opentelemetry/instrumentation/grpc/v1_6/TracingServerInterceptor.java b/instrumentation/grpc-1.6/library/src/main/java/io/opentelemetry/instrumentation/grpc/v1_6/TracingServerInterceptor.java
index b79ec2cbd8a5..eb9801dca7e3 100644
--- a/instrumentation/grpc-1.6/library/src/main/java/io/opentelemetry/instrumentation/grpc/v1_6/TracingServerInterceptor.java
+++ b/instrumentation/grpc-1.6/library/src/main/java/io/opentelemetry/instrumentation/grpc/v1_6/TracingServerInterceptor.java
@@ -51,7 +51,7 @@ public <REQUEST, RESPONSE> ServerCall.Listener<REQUEST> interceptCall(
     try (Scope ignored = context.makeCurrent()) {
       return new TracingServerCall<>(call, context, request).start(headers, next);
     } catch (Throwable e) {
-      instrumenter.end(context, request, null, e);
+      instrumenter.end(context, request, Status.UNKNOWN, e);
       throw e;
     }
   }
@@ -132,7 +132,7 @@ public void onHalfClose() {
         try {
           delegate().onHalfClose();
         } catch (Throwable e) {
-          instrumenter.end(context, request, null, e);
+          instrumenter.end(context, request, Status.UNKNOWN, e);
           throw e;
         }
       }
@@ -145,10 +145,10 @@ public void onCancel() {
             Span.fromContext(context).setAttribute("grpc.canceled", true);
           }
         } catch (Throwable e) {
-          instrumenter.end(context, request, null, e);
+          instrumenter.end(context, request, Status.UNKNOWN, e);
           throw e;
         }
-        instrumenter.end(context, request, null, null);
+        instrumenter.end(context, request, Status.CANCELLED, null);
       }
 
       @Override
@@ -156,7 +156,7 @@ public void onComplete() {
         try {
           delegate().onComplete();
         } catch (Throwable e) {
-          instrumenter.end(context, request, null, e);
+          instrumenter.end(context, request, Status.UNKNOWN, e);
           throw e;
         }
       }
@@ -166,7 +166,7 @@ public void onReady() {
         try {
           delegate().onReady();
         } catch (Throwable e) {
-          instrumenter.end(context, request, null, e);
+          instrumenter.end(context, request, Status.UNKNOWN, e);
           throw e;
         }
       }
diff --git a/instrumentation/grpc-1.6/testing/src/main/java/io/opentelemetry/instrumentation/grpc/v1_6/AbstractGrpcTest.java b/instrumentation/grpc-1.6/testing/src/main/java/io/opentelemetry/instrumentation/grpc/v1_6/AbstractGrpcTest.java
index dd87b7db9ecc..9fbb17402abd 100644
--- a/instrumentation/grpc-1.6/testing/src/main/java/io/opentelemetry/instrumentation/grpc/v1_6/AbstractGrpcTest.java
+++ b/instrumentation/grpc-1.6/testing/src/main/java/io/opentelemetry/instrumentation/grpc/v1_6/AbstractGrpcTest.java
@@ -881,7 +881,10 @@ public void sayHello(
                                     val -> assertThat(val).isNotNull()),
                                 equalTo(
                                     SemanticAttributes.NET_TRANSPORT,
-                                    SemanticAttributes.NetTransportValues.IP_TCP))
+                                    SemanticAttributes.NetTransportValues.IP_TCP),
+                                equalTo(
+                                    SemanticAttributes.RPC_GRPC_STATUS_CODE,
+                                    (long) Status.Code.UNKNOWN.value()))
                             .hasEventsSatisfying(
                                 events -> {
                                   assertThat(events).hasSize(2);
@@ -1289,7 +1292,10 @@ public void onCompleted() {
                                     val -> assertThat(val).isNotNull()),
                                 equalTo(
                                     SemanticAttributes.NET_TRANSPORT,
-                                    SemanticAttributes.NetTransportValues.IP_TCP))
+                                    SemanticAttributes.NetTransportValues.IP_TCP),
+                                equalTo(
+                                    SemanticAttributes.RPC_GRPC_STATUS_CODE,
+                                    (long) Status.Code.CANCELLED.value()))
                             .hasEventsSatisfyingExactly(
                                 event ->
                                     event