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dataspec.yml
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fasta_file: ../data/mm10.subset.fa # reference genome fasta file
task_specs: # specifies multiple tasks (e.g. Oct4, Sox2 Nanog)
Oct4:
tracks:
- ../data/chip-nexus/Oct4/counts.pos.subset.bw
- ../data/chip-nexus/Oct4/counts.neg.subset.bw
peaks: ../data/chip-nexus/Oct4/idr-optimal-set.summit.subset.bed.gz
Sox2:
tracks:
- ../data/chip-nexus/Sox2/counts.pos.subset.bw
- ../data/chip-nexus/Sox2/counts.neg.subset.bw
peaks: ../data/chip-nexus/Sox2/idr-optimal-set.summit.subset.bed.gz
Nanog: # Nanog is the task name
tracks:
# List of bigwig files (1 or more) corresponding to the task
# The model will predict each track individually (here coverage of
# reads mapping to the positive and negative strand) and
# the contribution scores will be averaged across all of these tracks
- ../data/chip-nexus/Nanog/counts.pos.subset.bw
- ../data/chip-nexus/Nanog/counts.neg.subset.bw
# Peaks associated with Nanog task (optional)
# These are used to later run TF-MoDISco for Nanog contrib scores
# only in the Nanog peaks.
peaks: ../data/chip-nexus/Nanog/idr-optimal-set.summit.subset.bed.gz
bias_specs: # specifies multiple bias tracks
input: # first bias track
tracks: # can specify multiple tracks
- ../data/chip-nexus/patchcap/counts.pos.subset.bw
- ../data/chip-nexus/patchcap/counts.neg.subset.bw
tasks: # applies to Oct4, Sox2, Nanog tasks
- Oct4
- Sox2
- Nanog
# NOTE: bias_specs don't specify peaks since they are only used
# to correct for biases