diff --git a/src/curation/upheno-fillers/ddpheno/abnormalAbsenceOfBiologicalProcess.tsv b/src/curation/upheno-fillers/ddpheno/abnormalAbsenceOfBiologicalProcess.tsv
new file mode 100644
index 00000000..85454179
--- /dev/null
+++ b/src/curation/upheno-fillers/ddpheno/abnormalAbsenceOfBiologicalProcess.tsv
@@ -0,0 +1,108 @@
+biological_process	defined_class
+http://purl.obolibrary.org/obo/GO_1902605	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0006412	http://purl.obolibrary.org/obo/UPHENO_0083294
+http://purl.obolibrary.org/obo/GO_1903013	http://purl.obolibrary.org/obo/UPHENO_0083295
+http://purl.obolibrary.org/obo/GO_0042554	http://purl.obolibrary.org/obo/UPHENO_0083296
+http://purl.obolibrary.org/obo/GO_0016339	http://purl.obolibrary.org/obo/UPHENO_0083298
+http://purl.obolibrary.org/obo/GO_0031150	http://purl.obolibrary.org/obo/UPHENO_0083299
+http://purl.obolibrary.org/obo/GO_1905037	http://purl.obolibrary.org/obo/UPHENO_0083300
+http://purl.obolibrary.org/obo/GO_0016338	http://purl.obolibrary.org/obo/UPHENO_0083301
+http://purl.obolibrary.org/obo/GO_0043408	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0033298	http://purl.obolibrary.org/obo/UPHENO_0083302
+http://purl.obolibrary.org/obo/GO_0031154	http://purl.obolibrary.org/obo/UPHENO_0083303
+http://purl.obolibrary.org/obo/GO_0033299	http://purl.obolibrary.org/obo/UPHENO_0083304
+http://purl.obolibrary.org/obo/GO_0031153	http://purl.obolibrary.org/obo/UPHENO_0083305
+http://purl.obolibrary.org/obo/GO_0032482	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0031152	http://purl.obolibrary.org/obo/UPHENO_0083306
+http://purl.obolibrary.org/obo/GO_0032486	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0006887	http://purl.obolibrary.org/obo/UPHENO_0083308
+http://purl.obolibrary.org/obo/GO_0030638	http://purl.obolibrary.org/obo/UPHENO_0083309
+http://purl.obolibrary.org/obo/GO_0097696	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0046107	http://purl.obolibrary.org/obo/UPHENO_0083311
+http://purl.obolibrary.org/obo/GO_0046105	http://purl.obolibrary.org/obo/UPHENO_0083312
+http://purl.obolibrary.org/obo/GO_0010467	http://purl.obolibrary.org/obo/UPHENO_0083313
+http://purl.obolibrary.org/obo/GO_0016601	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0019954	http://purl.obolibrary.org/obo/UPHENO_0083316
+http://purl.obolibrary.org/obo/GO_0036211	http://purl.obolibrary.org/obo/UPHENO_0083318
+http://purl.obolibrary.org/obo/GO_0036453	http://purl.obolibrary.org/obo/UPHENO_0083319
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UPHENO_0034024
+http://purl.obolibrary.org/obo/GO_0070177	http://purl.obolibrary.org/obo/UPHENO_0083320
+http://purl.obolibrary.org/obo/GO_0090383	http://purl.obolibrary.org/obo/UPHENO_0083322
+http://purl.obolibrary.org/obo/GO_0050830	http://purl.obolibrary.org/obo/UPHENO_0083323
+http://purl.obolibrary.org/obo/GO_0051641	http://purl.obolibrary.org/obo/UPHENO_0034074
+http://purl.obolibrary.org/obo/GO_0140459	http://purl.obolibrary.org/obo/UPHENO_0083324
+http://purl.obolibrary.org/obo/GO_1905146	http://purl.obolibrary.org/obo/UPHENO_0083325
+http://purl.obolibrary.org/obo/GO_0048870	http://purl.obolibrary.org/obo/UPHENO_0034076
+http://purl.obolibrary.org/obo/GO_0016236	http://purl.obolibrary.org/obo/UPHENO_0083328
+http://purl.obolibrary.org/obo/GO_0010498	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0034446	http://purl.obolibrary.org/obo/UPHENO_0083329
+http://purl.obolibrary.org/obo/GO_0071476	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0031054	http://purl.obolibrary.org/obo/UPHENO_0083330
+http://purl.obolibrary.org/obo/GO_0009306	http://purl.obolibrary.org/obo/UPHENO_0080964
+http://purl.obolibrary.org/obo/GO_0030244	http://purl.obolibrary.org/obo/UPHENO_0083333
+http://purl.obolibrary.org/obo/GO_0031589	http://purl.obolibrary.org/obo/UPHENO_0083334
+http://purl.obolibrary.org/obo/GO_0006303	http://purl.obolibrary.org/obo/UPHENO_0083335
+http://purl.obolibrary.org/obo/GO_0050821	http://purl.obolibrary.org/obo/UPHENO_0083336
+http://purl.obolibrary.org/obo/GO_0097352	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0097231	http://purl.obolibrary.org/obo/UPHENO_0083337
+http://purl.obolibrary.org/obo/GO_0006302	http://purl.obolibrary.org/obo/UPHENO_0083338
+http://purl.obolibrary.org/obo/GO_0006826	http://purl.obolibrary.org/obo/UPHENO_0083339
+http://purl.obolibrary.org/obo/GO_0140509	http://purl.obolibrary.org/obo/UPHENO_0083340
+http://purl.obolibrary.org/obo/GO_0043052	http://purl.obolibrary.org/obo/UPHENO_0083341
+http://purl.obolibrary.org/obo/GO_0048102	http://purl.obolibrary.org/obo/UPHENO_0083342
+http://purl.obolibrary.org/obo/GO_0050829	http://purl.obolibrary.org/obo/UPHENO_0083343
+http://purl.obolibrary.org/obo/GO_0140986	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0006661	http://purl.obolibrary.org/obo/UPHENO_0083344
+http://purl.obolibrary.org/obo/GO_0046847	http://purl.obolibrary.org/obo/UPHENO_0083345
+http://purl.obolibrary.org/obo/GO_0098609	http://purl.obolibrary.org/obo/UPHENO_0034021
+http://purl.obolibrary.org/obo/GO_0140460	http://purl.obolibrary.org/obo/UPHENO_0083346
+http://purl.obolibrary.org/obo/GO_0030010	http://purl.obolibrary.org/obo/UPHENO_0083347
+http://purl.obolibrary.org/obo/GO_0000724	http://purl.obolibrary.org/obo/UPHENO_0083348
+http://purl.obolibrary.org/obo/GO_0051591	http://purl.obolibrary.org/obo/UPHENO_0083349
+http://purl.obolibrary.org/obo/GO_0006974	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0097300	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0007264	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0007265	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0044655	http://purl.obolibrary.org/obo/UPHENO_0083351
+http://purl.obolibrary.org/obo/GO_0140676	http://purl.obolibrary.org/obo/UPHENO_0083353
+http://purl.obolibrary.org/obo/GO_0043326	http://purl.obolibrary.org/obo/UPHENO_0083354
+http://purl.obolibrary.org/obo/GO_0043327	http://purl.obolibrary.org/obo/UPHENO_0083355
+http://purl.obolibrary.org/obo/GO_0070921	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0000910	http://purl.obolibrary.org/obo/UPHENO_0083356
+http://purl.obolibrary.org/obo/GO_0009607	http://purl.obolibrary.org/obo/UPHENO_0083357
+http://purl.obolibrary.org/obo/GO_0008104	http://purl.obolibrary.org/obo/UPHENO_0034055
+http://purl.obolibrary.org/obo/GO_0007531	http://purl.obolibrary.org/obo/UPHENO_0083359
+http://purl.obolibrary.org/obo/GO_0042742	http://purl.obolibrary.org/obo/UPHENO_0083360
+http://purl.obolibrary.org/obo/GO_0006171	http://purl.obolibrary.org/obo/UPHENO_0083362
+http://purl.obolibrary.org/obo/GO_0140042	http://purl.obolibrary.org/obo/UPHENO_0083363
+http://purl.obolibrary.org/obo/GO_0097656	http://purl.obolibrary.org/obo/UPHENO_0083364
+http://purl.obolibrary.org/obo/GO_0032456	http://purl.obolibrary.org/obo/UPHENO_0083365
+http://purl.obolibrary.org/obo/GO_0030154	http://purl.obolibrary.org/obo/UPHENO_0083367
+http://purl.obolibrary.org/obo/GO_0006511	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0000012	http://purl.obolibrary.org/obo/UPHENO_0083371
+http://purl.obolibrary.org/obo/GO_0006911	http://purl.obolibrary.org/obo/UPHENO_0083372
+http://purl.obolibrary.org/obo/GO_0050919	http://purl.obolibrary.org/obo/UPHENO_0083373
+http://purl.obolibrary.org/obo/GO_0050918	http://purl.obolibrary.org/obo/UPHENO_0083374
+http://purl.obolibrary.org/obo/GO_0044351	http://purl.obolibrary.org/obo/UPHENO_0083375
+http://purl.obolibrary.org/obo/GO_0042330	http://purl.obolibrary.org/obo/UPHENO_0083376
+http://purl.obolibrary.org/obo/GO_0042331	http://purl.obolibrary.org/obo/UPHENO_0083377
+http://purl.obolibrary.org/obo/GO_1904892	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0038203	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0032060	http://purl.obolibrary.org/obo/UPHENO_0083378
+http://purl.obolibrary.org/obo/GO_0030042	http://purl.obolibrary.org/obo/UPHENO_0083379
+http://purl.obolibrary.org/obo/GO_0030041	http://purl.obolibrary.org/obo/UPHENO_0083380
+http://purl.obolibrary.org/obo/GO_0031148	http://purl.obolibrary.org/obo/UPHENO_0083382
+http://purl.obolibrary.org/obo/GO_0043491	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0007033	http://purl.obolibrary.org/obo/UPHENO_0083383
+http://purl.obolibrary.org/obo/GO_1903665	http://purl.obolibrary.org/obo/UPHENO_0083384
+http://purl.obolibrary.org/obo/GO_0140026	http://purl.obolibrary.org/obo/UPHENO_0083385
+http://purl.obolibrary.org/obo/GO_0140028	http://purl.obolibrary.org/obo/UPHENO_0083388
+http://purl.obolibrary.org/obo/GO_1903666	http://purl.obolibrary.org/obo/UPHENO_0083389
+http://purl.obolibrary.org/obo/GO_0019934	http://purl.obolibrary.org/obo/UPHENO_0083391
+http://purl.obolibrary.org/obo/GO_0012501	http://purl.obolibrary.org/obo/UPHENO_0034091
+http://purl.obolibrary.org/obo/GO_0140025	http://purl.obolibrary.org/obo/UPHENO_0083392
+http://purl.obolibrary.org/obo/GO_0043934	http://purl.obolibrary.org/obo/UPHENO_0083394
+http://purl.obolibrary.org/obo/GO_0033562	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0006907	http://purl.obolibrary.org/obo/UPHENO_0083395
+http://purl.obolibrary.org/obo/GO_0009617	http://purl.obolibrary.org/obo/UPHENO_0083396
+http://purl.obolibrary.org/obo/GO_0006909	http://purl.obolibrary.org/obo/UPHENO_0083397
diff --git a/src/curation/upheno-fillers/ddpheno/abnormalAbsenceOfChemicalEntity.tsv b/src/curation/upheno-fillers/ddpheno/abnormalAbsenceOfChemicalEntity.tsv
new file mode 100644
index 00000000..6e57343b
--- /dev/null
+++ b/src/curation/upheno-fillers/ddpheno/abnormalAbsenceOfChemicalEntity.tsv
@@ -0,0 +1,3 @@
+chemical_entity	defined_class
+http://purl.obolibrary.org/obo/CHEBI_36080	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CHEBI_24431	http://purl.obolibrary.org/obo/UPHENO_0048687
diff --git a/src/curation/upheno-fillers/ddpheno/abnormalAbsenceOfMolecularFunction.tsv b/src/curation/upheno-fillers/ddpheno/abnormalAbsenceOfMolecularFunction.tsv
new file mode 100644
index 00000000..72a42c0d
--- /dev/null
+++ b/src/curation/upheno-fillers/ddpheno/abnormalAbsenceOfMolecularFunction.tsv
@@ -0,0 +1,35 @@
+molecular_function	defined_class
+http://purl.obolibrary.org/obo/GO_0005096	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0004383	http://purl.obolibrary.org/obo/UPHENO_0083894
+http://purl.obolibrary.org/obo/GO_0016905	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0047555	http://purl.obolibrary.org/obo/UPHENO_0083895
+http://purl.obolibrary.org/obo/GO_0008289	http://purl.obolibrary.org/obo/UPHENO_0083896
+http://purl.obolibrary.org/obo/GO_0045499	http://purl.obolibrary.org/obo/UPHENO_0083898
+http://purl.obolibrary.org/obo/GO_0031545	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0035091	http://purl.obolibrary.org/obo/UPHENO_0083902
+http://purl.obolibrary.org/obo/GO_0003674	http://purl.obolibrary.org/obo/UPHENO_0081815
+http://purl.obolibrary.org/obo/GO_0005515	http://purl.obolibrary.org/obo/UPHENO_0083905
+http://purl.obolibrary.org/obo/GO_0004725	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0004129	http://purl.obolibrary.org/obo/UPHENO_0083906
+http://purl.obolibrary.org/obo/GO_0004407	http://purl.obolibrary.org/obo/UPHENO_0083907
+http://purl.obolibrary.org/obo/GO_0036094	http://purl.obolibrary.org/obo/UPHENO_0083908
+http://purl.obolibrary.org/obo/GO_0030552	http://purl.obolibrary.org/obo/UPHENO_0083909
+http://purl.obolibrary.org/obo/GO_0042800	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0004096	http://purl.obolibrary.org/obo/UPHENO_0083892
+http://purl.obolibrary.org/obo/GO_0005085	http://purl.obolibrary.org/obo/UPHENO_0083893
+http://purl.obolibrary.org/obo/GO_0010854	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0004672	http://purl.obolibrary.org/obo/UPHENO_0083897
+http://purl.obolibrary.org/obo/GO_0046974	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0010856	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0005542	http://purl.obolibrary.org/obo/UPHENO_0083899
+http://purl.obolibrary.org/obo/GO_0004671	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0004115	http://purl.obolibrary.org/obo/UPHENO_0083900
+http://purl.obolibrary.org/obo/GO_0004016	http://purl.obolibrary.org/obo/UPHENO_0083901
+http://purl.obolibrary.org/obo/GO_0005546	http://purl.obolibrary.org/obo/UPHENO_0083903
+http://purl.obolibrary.org/obo/GO_0030248	http://purl.obolibrary.org/obo/UPHENO_0083904
+http://purl.obolibrary.org/obo/GO_0004713	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0003886	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0016791	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0031151	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0003824	http://purl.obolibrary.org/obo/UPHENO_0081813
+http://purl.obolibrary.org/obo/GO_0019887	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/ddpheno/abnormalAbsenceOfProteinLocalizationInCellularComponent.tsv b/src/curation/upheno-fillers/ddpheno/abnormalAbsenceOfProteinLocalizationInCellularComponent.tsv
new file mode 100644
index 00000000..5e22029a
--- /dev/null
+++ b/src/curation/upheno-fillers/ddpheno/abnormalAbsenceOfProteinLocalizationInCellularComponent.tsv
@@ -0,0 +1,36 @@
+location	defined_class
+http://purl.obolibrary.org/obo/GO_0031254	http://purl.obolibrary.org/obo/UPHENO_0083600
+http://purl.obolibrary.org/obo/GO_0031410	http://purl.obolibrary.org/obo/UPHENO_0083601
+http://purl.obolibrary.org/obo/GO_0005905	http://purl.obolibrary.org/obo/UPHENO_0083602
+http://purl.obolibrary.org/obo/GO_0031252	http://purl.obolibrary.org/obo/UPHENO_0083603
+http://purl.obolibrary.org/obo/GO_0072686	http://purl.obolibrary.org/obo/UPHENO_0083604
+http://purl.obolibrary.org/obo/GO_0062201	http://purl.obolibrary.org/obo/UPHENO_0083605
+http://purl.obolibrary.org/obo/GO_0009986	http://purl.obolibrary.org/obo/UPHENO_0083606
+http://purl.obolibrary.org/obo/GO_0110085	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0044354	http://purl.obolibrary.org/obo/UPHENO_0083607
+http://purl.obolibrary.org/obo/GO_0000331	http://purl.obolibrary.org/obo/UPHENO_0083608
+http://purl.obolibrary.org/obo/GO_0005764	http://purl.obolibrary.org/obo/UPHENO_0083609
+http://purl.obolibrary.org/obo/GO_1990023	http://purl.obolibrary.org/obo/UPHENO_0083610
+http://purl.obolibrary.org/obo/GO_0005765	http://purl.obolibrary.org/obo/UPHENO_0083611
+http://purl.obolibrary.org/obo/GO_0005886	http://purl.obolibrary.org/obo/UPHENO_0083612
+http://purl.obolibrary.org/obo/GO_0044291	http://purl.obolibrary.org/obo/UPHENO_0083613
+http://purl.obolibrary.org/obo/GO_0005815	http://purl.obolibrary.org/obo/UPHENO_0083614
+http://purl.obolibrary.org/obo/GO_0005938	http://purl.obolibrary.org/obo/UPHENO_0083615
+http://purl.obolibrary.org/obo/GO_0031164	http://purl.obolibrary.org/obo/UPHENO_0083616
+http://purl.obolibrary.org/obo/GO_0032154	http://purl.obolibrary.org/obo/UPHENO_0083617
+http://purl.obolibrary.org/obo/GO_0030175	http://purl.obolibrary.org/obo/UPHENO_0083618
+http://purl.obolibrary.org/obo/GO_0031143	http://purl.obolibrary.org/obo/UPHENO_0083619
+http://purl.obolibrary.org/obo/GO_0032195	http://purl.obolibrary.org/obo/UPHENO_0083620
+http://purl.obolibrary.org/obo/GO_0036019	http://purl.obolibrary.org/obo/UPHENO_0083621
+http://purl.obolibrary.org/obo/GO_0071944	http://purl.obolibrary.org/obo/UPHENO_0083622
+http://purl.obolibrary.org/obo/GO_0016323	http://purl.obolibrary.org/obo/UPHENO_0083623
+http://purl.obolibrary.org/obo/GO_0016324	http://purl.obolibrary.org/obo/UPHENO_0083624
+http://purl.obolibrary.org/obo/GO_0045335	http://purl.obolibrary.org/obo/UPHENO_0083625
+http://purl.obolibrary.org/obo/GO_0005575	http://purl.obolibrary.org/obo/UPHENO_0083626
+http://purl.obolibrary.org/obo/GO_0005635	http://purl.obolibrary.org/obo/UPHENO_0083627
+http://purl.obolibrary.org/obo/GO_0005813	http://purl.obolibrary.org/obo/UPHENO_0083628
+http://purl.obolibrary.org/obo/GO_0005737	http://purl.obolibrary.org/obo/UPHENO_0083629
+http://purl.obolibrary.org/obo/GO_0005730	http://purl.obolibrary.org/obo/UPHENO_0083630
+http://purl.obolibrary.org/obo/GO_0005874	http://purl.obolibrary.org/obo/UPHENO_0083631
+http://purl.obolibrary.org/obo/GO_0005776	http://purl.obolibrary.org/obo/UPHENO_0083632
+http://purl.obolibrary.org/obo/GO_0005634	http://purl.obolibrary.org/obo/UPHENO_0083633
diff --git a/src/curation/upheno-fillers/ddpheno/abnormalBiologicalProcess.tsv b/src/curation/upheno-fillers/ddpheno/abnormalBiologicalProcess.tsv
new file mode 100644
index 00000000..c2ade418
--- /dev/null
+++ b/src/curation/upheno-fillers/ddpheno/abnormalBiologicalProcess.tsv
@@ -0,0 +1,208 @@
+biological_process	defined_class
+http://purl.obolibrary.org/obo/GO_1902605	http://purl.obolibrary.org/obo/UPHENO_0084757
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+http://purl.obolibrary.org/obo/GO_0043491	http://purl.obolibrary.org/obo/UPHENO_0050554
+http://purl.obolibrary.org/obo/GO_0006901	http://purl.obolibrary.org/obo/UPHENO_0083208
+http://purl.obolibrary.org/obo/GO_1903664	http://purl.obolibrary.org/obo/UPHENO_0083209
+http://purl.obolibrary.org/obo/GO_1903665	http://purl.obolibrary.org/obo/UPHENO_0083210
+http://purl.obolibrary.org/obo/GO_0009059	http://purl.obolibrary.org/obo/UPHENO_0049837
+http://purl.obolibrary.org/obo/GO_1903666	http://purl.obolibrary.org/obo/UPHENO_0083213
+http://purl.obolibrary.org/obo/GO_0019538	http://purl.obolibrary.org/obo/UPHENO_0050131
+http://purl.obolibrary.org/obo/GO_0043934	http://purl.obolibrary.org/obo/UPHENO_0083215
+http://purl.obolibrary.org/obo/GO_0006907	http://purl.obolibrary.org/obo/UPHENO_0083217
+http://purl.obolibrary.org/obo/GO_0009617	http://purl.obolibrary.org/obo/UPHENO_0051572
+http://purl.obolibrary.org/obo/GO_0006909	http://purl.obolibrary.org/obo/UPHENO_0051356
diff --git a/src/curation/upheno-fillers/ddpheno/abnormalCellularComponentProcess.tsv b/src/curation/upheno-fillers/ddpheno/abnormalCellularComponentProcess.tsv
new file mode 100644
index 00000000..dab9d597
--- /dev/null
+++ b/src/curation/upheno-fillers/ddpheno/abnormalCellularComponentProcess.tsv
@@ -0,0 +1,8 @@
+biological_process	cellular_component	defined_class
+http://purl.obolibrary.org/obo/GO_0070925	http://purl.obolibrary.org/obo/GO_0044352	http://purl.obolibrary.org/obo/UPHENO_0083010
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/GO_0044352	http://purl.obolibrary.org/obo/UPHENO_0083011
+http://purl.obolibrary.org/obo/GO_0006887	http://purl.obolibrary.org/obo/GO_0032195	http://purl.obolibrary.org/obo/UPHENO_0083012
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/GO_0032195	http://purl.obolibrary.org/obo/UPHENO_0083013
+http://purl.obolibrary.org/obo/GO_0070925	http://purl.obolibrary.org/obo/GO_0005575	http://purl.obolibrary.org/obo/UPHENO_0083014
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/GO_0005575	http://purl.obolibrary.org/obo/UPHENO_0083015
+http://purl.obolibrary.org/obo/GO_0006887	http://purl.obolibrary.org/obo/GO_0005575	http://purl.obolibrary.org/obo/UPHENO_0083016
diff --git a/src/curation/upheno-fillers/ddpheno/abnormalEfficacyOfProteinLocalizationInCellularComponent.tsv b/src/curation/upheno-fillers/ddpheno/abnormalEfficacyOfProteinLocalizationInCellularComponent.tsv
new file mode 100644
index 00000000..969062ab
--- /dev/null
+++ b/src/curation/upheno-fillers/ddpheno/abnormalEfficacyOfProteinLocalizationInCellularComponent.tsv
@@ -0,0 +1,35 @@
+location	defined_class
+http://purl.obolibrary.org/obo/GO_0031254	http://purl.obolibrary.org/obo/UPHENO_0082958
+http://purl.obolibrary.org/obo/GO_0031410	http://purl.obolibrary.org/obo/UPHENO_0082959
+http://purl.obolibrary.org/obo/GO_0005905	http://purl.obolibrary.org/obo/UPHENO_0082960
+http://purl.obolibrary.org/obo/GO_0031252	http://purl.obolibrary.org/obo/UPHENO_0082961
+http://purl.obolibrary.org/obo/GO_0072686	http://purl.obolibrary.org/obo/UPHENO_0082962
+http://purl.obolibrary.org/obo/GO_0062201	http://purl.obolibrary.org/obo/UPHENO_0082963
+http://purl.obolibrary.org/obo/GO_0009986	http://purl.obolibrary.org/obo/UPHENO_0082964
+http://purl.obolibrary.org/obo/GO_0110085	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0044354	http://purl.obolibrary.org/obo/UPHENO_0082965
+http://purl.obolibrary.org/obo/GO_0005764	http://purl.obolibrary.org/obo/UPHENO_0082966
+http://purl.obolibrary.org/obo/GO_1990023	http://purl.obolibrary.org/obo/UPHENO_0082967
+http://purl.obolibrary.org/obo/GO_0005765	http://purl.obolibrary.org/obo/UPHENO_0082968
+http://purl.obolibrary.org/obo/GO_0005886	http://purl.obolibrary.org/obo/UPHENO_0082969
+http://purl.obolibrary.org/obo/GO_0044291	http://purl.obolibrary.org/obo/UPHENO_0082970
+http://purl.obolibrary.org/obo/GO_0005815	http://purl.obolibrary.org/obo/UPHENO_0082971
+http://purl.obolibrary.org/obo/GO_0005938	http://purl.obolibrary.org/obo/UPHENO_0082972
+http://purl.obolibrary.org/obo/GO_0031164	http://purl.obolibrary.org/obo/UPHENO_0082973
+http://purl.obolibrary.org/obo/GO_0032154	http://purl.obolibrary.org/obo/UPHENO_0082974
+http://purl.obolibrary.org/obo/GO_0030175	http://purl.obolibrary.org/obo/UPHENO_0082975
+http://purl.obolibrary.org/obo/GO_0031143	http://purl.obolibrary.org/obo/UPHENO_0082976
+http://purl.obolibrary.org/obo/GO_0032195	http://purl.obolibrary.org/obo/UPHENO_0082977
+http://purl.obolibrary.org/obo/GO_0036019	http://purl.obolibrary.org/obo/UPHENO_0082978
+http://purl.obolibrary.org/obo/GO_0071944	http://purl.obolibrary.org/obo/UPHENO_0082979
+http://purl.obolibrary.org/obo/GO_0016323	http://purl.obolibrary.org/obo/UPHENO_0082980
+http://purl.obolibrary.org/obo/GO_0016324	http://purl.obolibrary.org/obo/UPHENO_0082981
+http://purl.obolibrary.org/obo/GO_0045335	http://purl.obolibrary.org/obo/UPHENO_0082982
+http://purl.obolibrary.org/obo/GO_0005575	http://purl.obolibrary.org/obo/UPHENO_0082983
+http://purl.obolibrary.org/obo/GO_0005635	http://purl.obolibrary.org/obo/UPHENO_0082984
+http://purl.obolibrary.org/obo/GO_0005813	http://purl.obolibrary.org/obo/UPHENO_0082985
+http://purl.obolibrary.org/obo/GO_0005737	http://purl.obolibrary.org/obo/UPHENO_0082986
+http://purl.obolibrary.org/obo/GO_0005730	http://purl.obolibrary.org/obo/UPHENO_0082987
+http://purl.obolibrary.org/obo/GO_0005874	http://purl.obolibrary.org/obo/UPHENO_0082988
+http://purl.obolibrary.org/obo/GO_0005776	http://purl.obolibrary.org/obo/UPHENO_0082989
+http://purl.obolibrary.org/obo/GO_0005634	http://purl.obolibrary.org/obo/UPHENO_0082990
diff --git a/src/curation/upheno-fillers/ddpheno/abnormalLevelOfChemicalEntity.tsv b/src/curation/upheno-fillers/ddpheno/abnormalLevelOfChemicalEntity.tsv
new file mode 100644
index 00000000..22d796b5
--- /dev/null
+++ b/src/curation/upheno-fillers/ddpheno/abnormalLevelOfChemicalEntity.tsv
@@ -0,0 +1,3 @@
+chemical_entity	defined_class
+http://purl.obolibrary.org/obo/CHEBI_36080	http://purl.obolibrary.org/obo/UPHENO_0046362
+http://purl.obolibrary.org/obo/CHEBI_24431	http://purl.obolibrary.org/obo/UPHENO_0046284
diff --git a/src/curation/upheno-fillers/ddpheno/abnormalMolecularFunction.tsv b/src/curation/upheno-fillers/ddpheno/abnormalMolecularFunction.tsv
new file mode 100644
index 00000000..9502714f
--- /dev/null
+++ b/src/curation/upheno-fillers/ddpheno/abnormalMolecularFunction.tsv
@@ -0,0 +1,33 @@
+molecular_function	defined_class
+http://purl.obolibrary.org/obo/GO_0005096	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0016905	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0008289	http://purl.obolibrary.org/obo/UPHENO_0083003
+http://purl.obolibrary.org/obo/GO_0045499	http://purl.obolibrary.org/obo/UPHENO_0083004
+http://purl.obolibrary.org/obo/GO_0031545	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0003674	http://purl.obolibrary.org/obo/UPHENO_0031743
+http://purl.obolibrary.org/obo/GO_0005515	http://purl.obolibrary.org/obo/UPHENO_0080029
+http://purl.obolibrary.org/obo/GO_0004725	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0030551	http://purl.obolibrary.org/obo/UPHENO_0083002
+http://purl.obolibrary.org/obo/GO_0016740	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0036094	http://purl.obolibrary.org/obo/UPHENO_0083006
+http://purl.obolibrary.org/obo/GO_0030695	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0042800	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0004096	http://purl.obolibrary.org/obo/UPHENO_0031745
+http://purl.obolibrary.org/obo/GO_0010854	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0004672	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0046974	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0010856	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0005542	http://purl.obolibrary.org/obo/UPHENO_0083005
+http://purl.obolibrary.org/obo/GO_0005102	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0004671	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0009008	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0030247	http://purl.obolibrary.org/obo/UPHENO_0083007
+http://purl.obolibrary.org/obo/GO_0005488	http://purl.obolibrary.org/obo/UPHENO_0083008
+http://purl.obolibrary.org/obo/GO_0030248	http://purl.obolibrary.org/obo/UPHENO_0083009
+http://purl.obolibrary.org/obo/GO_0004713	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0098772	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0003886	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0016791	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0031151	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0003824	http://purl.obolibrary.org/obo/UPHENO_0031742
+http://purl.obolibrary.org/obo/GO_0019887	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/ddpheno/abnormalMorphologyOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/ddpheno/abnormalMorphologyOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..809d19f8
--- /dev/null
+++ b/src/curation/upheno-fillers/ddpheno/abnormalMorphologyOfAnatomicalEntity.tsv
@@ -0,0 +1,79 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/GO_0000331	http://purl.obolibrary.org/obo/UPHENO_0085919
+http://purl.obolibrary.org/obo/GO_0005635	http://purl.obolibrary.org/obo/UPHENO_0085920
+http://purl.obolibrary.org/obo/GO_0005768	http://purl.obolibrary.org/obo/UPHENO_0085915
+http://purl.obolibrary.org/obo/GO_0005634	http://purl.obolibrary.org/obo/UPHENO_0077863
+http://purl.obolibrary.org/obo/GO_0005634	http://purl.obolibrary.org/obo/UPHENO_0077863
+http://purl.obolibrary.org/obo/GO_0005634	http://purl.obolibrary.org/obo/UPHENO_0077863
+http://purl.obolibrary.org/obo/GO_0005634	http://purl.obolibrary.org/obo/UPHENO_0077863
+http://purl.obolibrary.org/obo/GO_0043226	http://purl.obolibrary.org/obo/UPHENO_0085921
+http://purl.obolibrary.org/obo/GO_0005764	http://purl.obolibrary.org/obo/UPHENO_0085685
+http://purl.obolibrary.org/obo/GO_0005764	http://purl.obolibrary.org/obo/UPHENO_0085685
+http://purl.obolibrary.org/obo/GO_0005739	http://purl.obolibrary.org/obo/UPHENO_0085592
+http://purl.obolibrary.org/obo/GO_0005739	http://purl.obolibrary.org/obo/UPHENO_0085592
+http://purl.obolibrary.org/obo/GO_0005739	http://purl.obolibrary.org/obo/UPHENO_0085592
+http://purl.obolibrary.org/obo/GO_0005739	http://purl.obolibrary.org/obo/UPHENO_0085592
diff --git a/src/curation/upheno-fillers/ddpheno/abnormalMorphologyOfCellularComponent.tsv b/src/curation/upheno-fillers/ddpheno/abnormalMorphologyOfCellularComponent.tsv
new file mode 100644
index 00000000..c16fdac4
--- /dev/null
+++ b/src/curation/upheno-fillers/ddpheno/abnormalMorphologyOfCellularComponent.tsv
@@ -0,0 +1,9 @@
+cellular_component	defined_class
+http://purl.obolibrary.org/obo/GO_0005739	http://purl.obolibrary.org/obo/UPHENO_0067707
+http://purl.obolibrary.org/obo/GO_0005575	http://purl.obolibrary.org/obo/UPHENO_0067691
+http://purl.obolibrary.org/obo/GO_0005634	http://purl.obolibrary.org/obo/UPHENO_0067645
+http://purl.obolibrary.org/obo/GO_0043226	http://purl.obolibrary.org/obo/UPHENO_0084004
+http://purl.obolibrary.org/obo/GO_0005764	http://purl.obolibrary.org/obo/UPHENO_0067671
+http://purl.obolibrary.org/obo/GO_0000331	http://purl.obolibrary.org/obo/UPHENO_0084005
+http://purl.obolibrary.org/obo/GO_0005635	http://purl.obolibrary.org/obo/UPHENO_0084006
+http://purl.obolibrary.org/obo/GO_0005768	http://purl.obolibrary.org/obo/UPHENO_0067748
diff --git a/src/curation/upheno-fillers/ddpheno/abnormalMorphologyOfPartOfAnatomicalEntity-modified.tsv b/src/curation/upheno-fillers/ddpheno/abnormalMorphologyOfPartOfAnatomicalEntity-modified.tsv
new file mode 100644
index 00000000..8710aa78
--- /dev/null
+++ b/src/curation/upheno-fillers/ddpheno/abnormalMorphologyOfPartOfAnatomicalEntity-modified.tsv
@@ -0,0 +1,9 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0000331	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0005635	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0005768	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0005634	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0043226	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0005764	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0005739	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/ddpheno/abnormallyArrestedBiologicalProcess.tsv b/src/curation/upheno-fillers/ddpheno/abnormallyArrestedBiologicalProcess.tsv
new file mode 100644
index 00000000..9da09ae7
--- /dev/null
+++ b/src/curation/upheno-fillers/ddpheno/abnormallyArrestedBiologicalProcess.tsv
@@ -0,0 +1,4 @@
+biological_process	defined_class
+http://purl.obolibrary.org/obo/GO_0000087	http://purl.obolibrary.org/obo/UPHENO_0083064
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UPHENO_0018635
+http://purl.obolibrary.org/obo/GO_0000080	http://purl.obolibrary.org/obo/UPHENO_0018795
diff --git a/src/curation/upheno-fillers/ddpheno/abnormallyDecreasedEfficacyOfProteinLocalizationInCellularComponent.tsv b/src/curation/upheno-fillers/ddpheno/abnormallyDecreasedEfficacyOfProteinLocalizationInCellularComponent.tsv
new file mode 100644
index 00000000..44537cde
--- /dev/null
+++ b/src/curation/upheno-fillers/ddpheno/abnormallyDecreasedEfficacyOfProteinLocalizationInCellularComponent.tsv
@@ -0,0 +1,34 @@
+location	defined_class
+http://purl.obolibrary.org/obo/GO_0031254	http://purl.obolibrary.org/obo/UPHENO_0083476
+http://purl.obolibrary.org/obo/GO_0031410	http://purl.obolibrary.org/obo/UPHENO_0083477
+http://purl.obolibrary.org/obo/GO_0005905	http://purl.obolibrary.org/obo/UPHENO_0083478
+http://purl.obolibrary.org/obo/GO_0031252	http://purl.obolibrary.org/obo/UPHENO_0083479
+http://purl.obolibrary.org/obo/GO_0072686	http://purl.obolibrary.org/obo/UPHENO_0083480
+http://purl.obolibrary.org/obo/GO_0062201	http://purl.obolibrary.org/obo/UPHENO_0083481
+http://purl.obolibrary.org/obo/GO_0009986	http://purl.obolibrary.org/obo/UPHENO_0083482
+http://purl.obolibrary.org/obo/GO_0110085	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0044354	http://purl.obolibrary.org/obo/UPHENO_0083483
+http://purl.obolibrary.org/obo/GO_0000331	http://purl.obolibrary.org/obo/UPHENO_0083484
+http://purl.obolibrary.org/obo/GO_0005764	http://purl.obolibrary.org/obo/UPHENO_0083485
+http://purl.obolibrary.org/obo/GO_1990023	http://purl.obolibrary.org/obo/UPHENO_0083486
+http://purl.obolibrary.org/obo/GO_0005765	http://purl.obolibrary.org/obo/UPHENO_0083487
+http://purl.obolibrary.org/obo/GO_0005886	http://purl.obolibrary.org/obo/UPHENO_0083488
+http://purl.obolibrary.org/obo/GO_0044291	http://purl.obolibrary.org/obo/UPHENO_0083489
+http://purl.obolibrary.org/obo/GO_0005815	http://purl.obolibrary.org/obo/UPHENO_0083490
+http://purl.obolibrary.org/obo/GO_0005938	http://purl.obolibrary.org/obo/UPHENO_0083491
+http://purl.obolibrary.org/obo/GO_0031164	http://purl.obolibrary.org/obo/UPHENO_0083492
+http://purl.obolibrary.org/obo/GO_0032154	http://purl.obolibrary.org/obo/UPHENO_0083493
+http://purl.obolibrary.org/obo/GO_0030175	http://purl.obolibrary.org/obo/UPHENO_0083494
+http://purl.obolibrary.org/obo/GO_0031143	http://purl.obolibrary.org/obo/UPHENO_0083495
+http://purl.obolibrary.org/obo/GO_0032195	http://purl.obolibrary.org/obo/UPHENO_0083496
+http://purl.obolibrary.org/obo/GO_0036019	http://purl.obolibrary.org/obo/UPHENO_0083497
+http://purl.obolibrary.org/obo/GO_0016323	http://purl.obolibrary.org/obo/UPHENO_0083498
+http://purl.obolibrary.org/obo/GO_0045335	http://purl.obolibrary.org/obo/UPHENO_0083499
+http://purl.obolibrary.org/obo/GO_0005575	http://purl.obolibrary.org/obo/UPHENO_0083500
+http://purl.obolibrary.org/obo/GO_0005635	http://purl.obolibrary.org/obo/UPHENO_0083501
+http://purl.obolibrary.org/obo/GO_0005813	http://purl.obolibrary.org/obo/UPHENO_0083502
+http://purl.obolibrary.org/obo/GO_0005737	http://purl.obolibrary.org/obo/UPHENO_0083503
+http://purl.obolibrary.org/obo/GO_0005730	http://purl.obolibrary.org/obo/UPHENO_0083504
+http://purl.obolibrary.org/obo/GO_0005874	http://purl.obolibrary.org/obo/UPHENO_0083505
+http://purl.obolibrary.org/obo/GO_0005776	http://purl.obolibrary.org/obo/UPHENO_0083506
+http://purl.obolibrary.org/obo/GO_0005634	http://purl.obolibrary.org/obo/UPHENO_0083507
diff --git a/src/curation/upheno-fillers/ddpheno/abnormallyDecreasedLevelOfChemicalEntity.tsv b/src/curation/upheno-fillers/ddpheno/abnormallyDecreasedLevelOfChemicalEntity.tsv
new file mode 100644
index 00000000..04d71079
--- /dev/null
+++ b/src/curation/upheno-fillers/ddpheno/abnormallyDecreasedLevelOfChemicalEntity.tsv
@@ -0,0 +1,6 @@
+chemical_entity	defined_class
+http://purl.obolibrary.org/obo/CHEBI_36080	http://purl.obolibrary.org/obo/UPHENO_0081724
+http://purl.obolibrary.org/obo/CHEBI_15422	http://purl.obolibrary.org/obo/UPHENO_0066792
+http://purl.obolibrary.org/obo/CHEBI_24431	http://purl.obolibrary.org/obo/UPHENO_0066739
+http://purl.obolibrary.org/obo/CHEBI_35366	http://purl.obolibrary.org/obo/UPHENO_0066749
+http://purl.obolibrary.org/obo/CHEBI_16134	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/ddpheno/abnormallyDecreasedNumberOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/ddpheno/abnormallyDecreasedNumberOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..657c96f6
--- /dev/null
+++ b/src/curation/upheno-fillers/ddpheno/abnormallyDecreasedNumberOfAnatomicalEntity.tsv
@@ -0,0 +1,7 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0063722
+http://purl.obolibrary.org/obo/GO_0032195	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0005776	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0000235	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0005773	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0005739	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/ddpheno/abnormallyDecreasedNumberOfCellularComponent.tsv b/src/curation/upheno-fillers/ddpheno/abnormallyDecreasedNumberOfCellularComponent.tsv
new file mode 100644
index 00000000..1584edf7
--- /dev/null
+++ b/src/curation/upheno-fillers/ddpheno/abnormallyDecreasedNumberOfCellularComponent.tsv
@@ -0,0 +1,7 @@
+cellular_component	defined_class
+http://purl.obolibrary.org/obo/GO_0005739	http://purl.obolibrary.org/obo/UPHENO_0046250
+http://purl.obolibrary.org/obo/GO_0005575	http://purl.obolibrary.org/obo/UPHENO_0046252
+http://purl.obolibrary.org/obo/GO_0005773	http://purl.obolibrary.org/obo/UPHENO_0084206
+http://purl.obolibrary.org/obo/GO_0005776	http://purl.obolibrary.org/obo/UPHENO_0082676
+http://purl.obolibrary.org/obo/GO_0000235	http://purl.obolibrary.org/obo/UPHENO_0084207
+http://purl.obolibrary.org/obo/GO_0032195	http://purl.obolibrary.org/obo/UPHENO_0084208
diff --git a/src/curation/upheno-fillers/ddpheno/abnormallyDecreasedOccurrenceOfBiologicalProcess.tsv b/src/curation/upheno-fillers/ddpheno/abnormallyDecreasedOccurrenceOfBiologicalProcess.tsv
new file mode 100644
index 00000000..1f3a18ec
--- /dev/null
+++ b/src/curation/upheno-fillers/ddpheno/abnormallyDecreasedOccurrenceOfBiologicalProcess.tsv
@@ -0,0 +1,116 @@
+biological_process	defined_class
+http://purl.obolibrary.org/obo/GO_1902605	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0099120	http://purl.obolibrary.org/obo/UPHENO_0084262
+http://purl.obolibrary.org/obo/GO_0006412	http://purl.obolibrary.org/obo/UPHENO_0084263
+http://purl.obolibrary.org/obo/GO_1903013	http://purl.obolibrary.org/obo/UPHENO_0084264
+http://purl.obolibrary.org/obo/GO_0042554	http://purl.obolibrary.org/obo/UPHENO_0084265
+http://purl.obolibrary.org/obo/GO_0016339	http://purl.obolibrary.org/obo/UPHENO_0084267
+http://purl.obolibrary.org/obo/GO_0031271	http://purl.obolibrary.org/obo/UPHENO_0084268
+http://purl.obolibrary.org/obo/GO_1905037	http://purl.obolibrary.org/obo/UPHENO_0084269
+http://purl.obolibrary.org/obo/GO_0016338	http://purl.obolibrary.org/obo/UPHENO_0084270
+http://purl.obolibrary.org/obo/GO_0031270	http://purl.obolibrary.org/obo/UPHENO_0084271
+http://purl.obolibrary.org/obo/GO_0043408	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0031154	http://purl.obolibrary.org/obo/UPHENO_0084272
+http://purl.obolibrary.org/obo/GO_0033299	http://purl.obolibrary.org/obo/UPHENO_0084273
+http://purl.obolibrary.org/obo/GO_0032482	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0031036	http://purl.obolibrary.org/obo/UPHENO_0084274
+http://purl.obolibrary.org/obo/GO_0032486	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0006887	http://purl.obolibrary.org/obo/UPHENO_0084276
+http://purl.obolibrary.org/obo/GO_0051017	http://purl.obolibrary.org/obo/UPHENO_0084277
+http://purl.obolibrary.org/obo/GO_0045010	http://purl.obolibrary.org/obo/UPHENO_0084278
+http://purl.obolibrary.org/obo/GO_0097178	http://purl.obolibrary.org/obo/UPHENO_0084279
+http://purl.obolibrary.org/obo/GO_0000266	http://purl.obolibrary.org/obo/UPHENO_0084280
+http://purl.obolibrary.org/obo/GO_0010226	http://purl.obolibrary.org/obo/UPHENO_0084281
+http://purl.obolibrary.org/obo/GO_0010467	http://purl.obolibrary.org/obo/UPHENO_0082858
+http://purl.obolibrary.org/obo/GO_0016601	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0036211	http://purl.obolibrary.org/obo/UPHENO_0084285
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UPHENO_0077429
+http://purl.obolibrary.org/obo/GO_0034670	http://purl.obolibrary.org/obo/UPHENO_0084286
+http://purl.obolibrary.org/obo/GO_0070177	http://purl.obolibrary.org/obo/UPHENO_0084287
+http://purl.obolibrary.org/obo/GO_0008219	http://purl.obolibrary.org/obo/UPHENO_0082838
+http://purl.obolibrary.org/obo/GO_0007009	http://purl.obolibrary.org/obo/UPHENO_0084289
+http://purl.obolibrary.org/obo/GO_0050832	http://purl.obolibrary.org/obo/UPHENO_0084290
+http://purl.obolibrary.org/obo/GO_0050830	http://purl.obolibrary.org/obo/UPHENO_0084291
+http://purl.obolibrary.org/obo/GO_0051641	http://purl.obolibrary.org/obo/UPHENO_0084292
+http://purl.obolibrary.org/obo/GO_0140459	http://purl.obolibrary.org/obo/UPHENO_0084294
+http://purl.obolibrary.org/obo/GO_1905146	http://purl.obolibrary.org/obo/UPHENO_0084295
+http://purl.obolibrary.org/obo/GO_0048870	http://purl.obolibrary.org/obo/UPHENO_0084296
+http://purl.obolibrary.org/obo/GO_0016236	http://purl.obolibrary.org/obo/UPHENO_0084297
+http://purl.obolibrary.org/obo/GO_0001709	http://purl.obolibrary.org/obo/UPHENO_0084298
+http://purl.obolibrary.org/obo/GO_0010498	http://purl.obolibrary.org/obo/UPHENO_0077484
+http://purl.obolibrary.org/obo/GO_0034446	http://purl.obolibrary.org/obo/UPHENO_0084299
+http://purl.obolibrary.org/obo/GO_0071476	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0031054	http://purl.obolibrary.org/obo/UPHENO_0084300
+http://purl.obolibrary.org/obo/GO_0009306	http://purl.obolibrary.org/obo/UPHENO_0084302
+http://purl.obolibrary.org/obo/GO_0030244	http://purl.obolibrary.org/obo/UPHENO_0084303
+http://purl.obolibrary.org/obo/GO_1900756	http://purl.obolibrary.org/obo/UPHENO_0084304
+http://purl.obolibrary.org/obo/GO_0031589	http://purl.obolibrary.org/obo/UPHENO_0084305
+http://purl.obolibrary.org/obo/GO_0006303	http://purl.obolibrary.org/obo/UPHENO_0084306
+http://purl.obolibrary.org/obo/GO_0050821	http://purl.obolibrary.org/obo/UPHENO_0084307
+http://purl.obolibrary.org/obo/GO_0097352	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0006302	http://purl.obolibrary.org/obo/UPHENO_0084308
+http://purl.obolibrary.org/obo/GO_0140509	http://purl.obolibrary.org/obo/UPHENO_0084309
+http://purl.obolibrary.org/obo/GO_0043052	http://purl.obolibrary.org/obo/UPHENO_0084310
+http://purl.obolibrary.org/obo/GO_0048102	http://purl.obolibrary.org/obo/UPHENO_0084311
+http://purl.obolibrary.org/obo/GO_0050829	http://purl.obolibrary.org/obo/UPHENO_0084312
+http://purl.obolibrary.org/obo/GO_0045110	http://purl.obolibrary.org/obo/UPHENO_0084313
+http://purl.obolibrary.org/obo/GO_0140986	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0006661	http://purl.obolibrary.org/obo/UPHENO_0084314
+http://purl.obolibrary.org/obo/GO_0046847	http://purl.obolibrary.org/obo/UPHENO_0077690
+http://purl.obolibrary.org/obo/GO_0098609	http://purl.obolibrary.org/obo/UPHENO_0077691
+http://purl.obolibrary.org/obo/GO_0008053	http://purl.obolibrary.org/obo/UPHENO_0084315
+http://purl.obolibrary.org/obo/GO_0140460	http://purl.obolibrary.org/obo/UPHENO_0084316
+http://purl.obolibrary.org/obo/GO_0030010	http://purl.obolibrary.org/obo/UPHENO_0084317
+http://purl.obolibrary.org/obo/GO_0034058	http://purl.obolibrary.org/obo/UPHENO_0084318
+http://purl.obolibrary.org/obo/GO_0000724	http://purl.obolibrary.org/obo/UPHENO_0084319
+http://purl.obolibrary.org/obo/GO_0051591	http://purl.obolibrary.org/obo/UPHENO_0084320
+http://purl.obolibrary.org/obo/GO_0006974	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0097300	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0007264	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0007265	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0007020	http://purl.obolibrary.org/obo/UPHENO_0084322
+http://purl.obolibrary.org/obo/GO_0140676	http://purl.obolibrary.org/obo/UPHENO_0084324
+http://purl.obolibrary.org/obo/GO_0043326	http://purl.obolibrary.org/obo/UPHENO_0084325
+http://purl.obolibrary.org/obo/GO_0043327	http://purl.obolibrary.org/obo/UPHENO_0084326
+http://purl.obolibrary.org/obo/GO_0120320	http://purl.obolibrary.org/obo/UPHENO_0084327
+http://purl.obolibrary.org/obo/GO_0070921	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0006182	http://purl.obolibrary.org/obo/UPHENO_0084328
+http://purl.obolibrary.org/obo/GO_0001845	http://purl.obolibrary.org/obo/UPHENO_0084329
+http://purl.obolibrary.org/obo/GO_0034461	http://purl.obolibrary.org/obo/UPHENO_0084331
+http://purl.obolibrary.org/obo/GO_0071456	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0009847	http://purl.obolibrary.org/obo/UPHENO_0084332
+http://purl.obolibrary.org/obo/GO_0070370	http://purl.obolibrary.org/obo/UPHENO_0084333
+http://purl.obolibrary.org/obo/GO_0008104	http://purl.obolibrary.org/obo/UPHENO_0084334
+http://purl.obolibrary.org/obo/GO_0042742	http://purl.obolibrary.org/obo/UPHENO_0077730
+http://purl.obolibrary.org/obo/GO_0006171	http://purl.obolibrary.org/obo/UPHENO_0084335
+http://purl.obolibrary.org/obo/GO_0140042	http://purl.obolibrary.org/obo/UPHENO_0084336
+http://purl.obolibrary.org/obo/GO_0051452	http://purl.obolibrary.org/obo/UPHENO_0084337
+http://purl.obolibrary.org/obo/GO_0097656	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0032456	http://purl.obolibrary.org/obo/UPHENO_0084338
+http://purl.obolibrary.org/obo/GO_0000747	http://purl.obolibrary.org/obo/UPHENO_0084340
+http://purl.obolibrary.org/obo/GO_0030154	http://purl.obolibrary.org/obo/UPHENO_0084341
+http://purl.obolibrary.org/obo/GO_0006511	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0006914	http://purl.obolibrary.org/obo/UPHENO_0077755
+http://purl.obolibrary.org/obo/GO_0000012	http://purl.obolibrary.org/obo/UPHENO_0084342
+http://purl.obolibrary.org/obo/GO_0006911	http://purl.obolibrary.org/obo/UPHENO_0077757
+http://purl.obolibrary.org/obo/GO_0050919	http://purl.obolibrary.org/obo/UPHENO_0084343
+http://purl.obolibrary.org/obo/GO_0044351	http://purl.obolibrary.org/obo/UPHENO_0084344
+http://purl.obolibrary.org/obo/GO_0042330	http://purl.obolibrary.org/obo/UPHENO_0077567
+http://purl.obolibrary.org/obo/GO_0042331	http://purl.obolibrary.org/obo/UPHENO_0084253
+http://purl.obolibrary.org/obo/GO_1904892	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0038203	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0070509	http://purl.obolibrary.org/obo/UPHENO_0084346
+http://purl.obolibrary.org/obo/GO_0032060	http://purl.obolibrary.org/obo/UPHENO_0084347
+http://purl.obolibrary.org/obo/GO_0030042	http://purl.obolibrary.org/obo/UPHENO_0084348
+http://purl.obolibrary.org/obo/GO_0030041	http://purl.obolibrary.org/obo/UPHENO_0077578
+http://purl.obolibrary.org/obo/GO_0033275	http://purl.obolibrary.org/obo/UPHENO_0084349
+http://purl.obolibrary.org/obo/GO_0031148	http://purl.obolibrary.org/obo/UPHENO_0084350
+http://purl.obolibrary.org/obo/GO_0031269	http://purl.obolibrary.org/obo/UPHENO_0084351
+http://purl.obolibrary.org/obo/GO_0043491	http://purl.obolibrary.org/obo/UPHENO_0077780
+http://purl.obolibrary.org/obo/GO_0019934	http://purl.obolibrary.org/obo/UPHENO_0084352
+http://purl.obolibrary.org/obo/GO_0012501	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0043934	http://purl.obolibrary.org/obo/UPHENO_0084354
+http://purl.obolibrary.org/obo/GO_0033562	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0006907	http://purl.obolibrary.org/obo/UPHENO_0084355
+http://purl.obolibrary.org/obo/GO_0009617	http://purl.obolibrary.org/obo/UPHENO_0084356
+http://purl.obolibrary.org/obo/GO_0006909	http://purl.obolibrary.org/obo/UPHENO_0077798
diff --git a/src/curation/upheno-fillers/ddpheno/abnormallyDecreasedRateOfBiologicalProcess.tsv b/src/curation/upheno-fillers/ddpheno/abnormallyDecreasedRateOfBiologicalProcess.tsv
new file mode 100644
index 00000000..ad3044cf
--- /dev/null
+++ b/src/curation/upheno-fillers/ddpheno/abnormallyDecreasedRateOfBiologicalProcess.tsv
@@ -0,0 +1,5 @@
+biological_process	defined_class
+http://purl.obolibrary.org/obo/GO_0019954	http://purl.obolibrary.org/obo/UPHENO_0082952
+http://purl.obolibrary.org/obo/GO_0006897	http://purl.obolibrary.org/obo/UPHENO_0082953
+http://purl.obolibrary.org/obo/GO_0006935	http://purl.obolibrary.org/obo/UPHENO_0082954
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UPHENO_0005433
diff --git a/src/curation/upheno-fillers/ddpheno/abnormallyDecreasedRateOfMolecularFunction.tsv b/src/curation/upheno-fillers/ddpheno/abnormallyDecreasedRateOfMolecularFunction.tsv
new file mode 100644
index 00000000..4d463f9a
--- /dev/null
+++ b/src/curation/upheno-fillers/ddpheno/abnormallyDecreasedRateOfMolecularFunction.tsv
@@ -0,0 +1,29 @@
+molecular_function	defined_class
+http://purl.obolibrary.org/obo/GO_0005096	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0004383	http://purl.obolibrary.org/obo/UPHENO_0083268
+http://purl.obolibrary.org/obo/GO_0047555	http://purl.obolibrary.org/obo/UPHENO_0083269
+http://purl.obolibrary.org/obo/GO_0008289	http://purl.obolibrary.org/obo/UPHENO_0083270
+http://purl.obolibrary.org/obo/GO_0045499	http://purl.obolibrary.org/obo/UPHENO_0083272
+http://purl.obolibrary.org/obo/GO_0031545	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0003674	http://purl.obolibrary.org/obo/UPHENO_0066865
+http://purl.obolibrary.org/obo/GO_0005515	http://purl.obolibrary.org/obo/UPHENO_0083277
+http://purl.obolibrary.org/obo/GO_0004725	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0004129	http://purl.obolibrary.org/obo/UPHENO_0083278
+http://purl.obolibrary.org/obo/GO_0004407	http://purl.obolibrary.org/obo/UPHENO_0083279
+http://purl.obolibrary.org/obo/GO_0036094	http://purl.obolibrary.org/obo/UPHENO_0083280
+http://purl.obolibrary.org/obo/GO_0030552	http://purl.obolibrary.org/obo/UPHENO_0083281
+http://purl.obolibrary.org/obo/GO_0004096	http://purl.obolibrary.org/obo/UPHENO_0066872
+http://purl.obolibrary.org/obo/GO_0005085	http://purl.obolibrary.org/obo/UPHENO_0083267
+http://purl.obolibrary.org/obo/GO_0010854	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0004672	http://purl.obolibrary.org/obo/UPHENO_0083271
+http://purl.obolibrary.org/obo/GO_0010856	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0005542	http://purl.obolibrary.org/obo/UPHENO_0083273
+http://purl.obolibrary.org/obo/GO_0004115	http://purl.obolibrary.org/obo/UPHENO_0083274
+http://purl.obolibrary.org/obo/GO_0009008	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0004016	http://purl.obolibrary.org/obo/UPHENO_0083275
+http://purl.obolibrary.org/obo/GO_0030248	http://purl.obolibrary.org/obo/UPHENO_0083276
+http://purl.obolibrary.org/obo/GO_0004713	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0003886	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0016791	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0003824	http://purl.obolibrary.org/obo/UPHENO_0066897
+http://purl.obolibrary.org/obo/GO_0019887	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/ddpheno/abnormallyDecreasedResistanceOfWholeOrganismToChemicalEntity.tsv b/src/curation/upheno-fillers/ddpheno/abnormallyDecreasedResistanceOfWholeOrganismToChemicalEntity.tsv
new file mode 100644
index 00000000..2bc0ce6d
--- /dev/null
+++ b/src/curation/upheno-fillers/ddpheno/abnormallyDecreasedResistanceOfWholeOrganismToChemicalEntity.tsv
@@ -0,0 +1,3 @@
+chemical_entity	defined_class
+http://purl.obolibrary.org/obo/CHEBI_24431	http://purl.obolibrary.org/obo/UPHENO_0076332
+http://purl.obolibrary.org/obo/CHEBI_16240	http://purl.obolibrary.org/obo/UPHENO_0076502
diff --git a/src/curation/upheno-fillers/ddpheno/abnormallyDecreasedResistanceOfWholeOrganismToEntity.tsv b/src/curation/upheno-fillers/ddpheno/abnormallyDecreasedResistanceOfWholeOrganismToEntity.tsv
new file mode 100644
index 00000000..7ea45ff7
--- /dev/null
+++ b/src/curation/upheno-fillers/ddpheno/abnormallyDecreasedResistanceOfWholeOrganismToEntity.tsv
@@ -0,0 +1,3 @@
+entity	defined_class
+http://purl.obolibrary.org/obo/CHEBI_16240	http://purl.obolibrary.org/obo/UPHENO_0076260
+http://purl.obolibrary.org/obo/BFO_0000001	http://purl.obolibrary.org/obo/UPHENO_0081418
diff --git a/src/curation/upheno-fillers/ddpheno/abnormallyDecreasedSizeOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/ddpheno/abnormallyDecreasedSizeOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..a134431c
--- /dev/null
+++ b/src/curation/upheno-fillers/ddpheno/abnormallyDecreasedSizeOfAnatomicalEntity.tsv
@@ -0,0 +1,10 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0068971
+http://purl.obolibrary.org/obo/GO_0032195	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0000331	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0005768	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0000235	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0005764	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0031143	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0032010	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0044352	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/ddpheno/abnormallyDecreasedSizeOfCellularComponent.tsv b/src/curation/upheno-fillers/ddpheno/abnormallyDecreasedSizeOfCellularComponent.tsv
new file mode 100644
index 00000000..8e5fdd39
--- /dev/null
+++ b/src/curation/upheno-fillers/ddpheno/abnormallyDecreasedSizeOfCellularComponent.tsv
@@ -0,0 +1,10 @@
+entity	defined_class
+http://purl.obolibrary.org/obo/GO_0032010	http://purl.obolibrary.org/obo/UPHENO_0083992
+http://purl.obolibrary.org/obo/GO_0044352	http://purl.obolibrary.org/obo/UPHENO_0083993
+http://purl.obolibrary.org/obo/GO_0031143	http://purl.obolibrary.org/obo/UPHENO_0083994
+http://purl.obolibrary.org/obo/GO_0005575	http://purl.obolibrary.org/obo/UPHENO_0082013
+http://purl.obolibrary.org/obo/GO_0000235	http://purl.obolibrary.org/obo/UPHENO_0083996
+http://purl.obolibrary.org/obo/GO_0005764	http://purl.obolibrary.org/obo/UPHENO_0083997
+http://purl.obolibrary.org/obo/GO_0005768	http://purl.obolibrary.org/obo/UPHENO_0083998
+http://purl.obolibrary.org/obo/GO_0032195	http://purl.obolibrary.org/obo/UPHENO_0083999
+http://purl.obolibrary.org/obo/GO_0000331	http://purl.obolibrary.org/obo/UPHENO_0084000
diff --git a/src/curation/upheno-fillers/ddpheno/abnormallyDelayedBiologicalProcess.tsv b/src/curation/upheno-fillers/ddpheno/abnormallyDelayedBiologicalProcess.tsv
new file mode 100644
index 00000000..87f2e11a
--- /dev/null
+++ b/src/curation/upheno-fillers/ddpheno/abnormallyDelayedBiologicalProcess.tsv
@@ -0,0 +1,18 @@
+biological_process	defined_class
+http://purl.obolibrary.org/obo/GO_0030587	http://purl.obolibrary.org/obo/UPHENO_0083046
+http://purl.obolibrary.org/obo/GO_0031269	http://purl.obolibrary.org/obo/UPHENO_0083047
+http://purl.obolibrary.org/obo/GO_0000022	http://purl.obolibrary.org/obo/UPHENO_0083048
+http://purl.obolibrary.org/obo/GO_1903013	http://purl.obolibrary.org/obo/UPHENO_0083049
+http://purl.obolibrary.org/obo/GO_0006972	http://purl.obolibrary.org/obo/UPHENO_0083050
+http://purl.obolibrary.org/obo/GO_0044655	http://purl.obolibrary.org/obo/UPHENO_0083051
+http://purl.obolibrary.org/obo/GO_0006971	http://purl.obolibrary.org/obo/UPHENO_0083052
+http://purl.obolibrary.org/obo/GO_0061952	http://purl.obolibrary.org/obo/UPHENO_0083053
+http://purl.obolibrary.org/obo/GO_0010467	http://purl.obolibrary.org/obo/UPHENO_0083054
+http://purl.obolibrary.org/obo/GO_0043934	http://purl.obolibrary.org/obo/UPHENO_0083055
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UPHENO_0000543
+http://purl.obolibrary.org/obo/GO_0031154	http://purl.obolibrary.org/obo/UPHENO_0083056
+http://purl.obolibrary.org/obo/GO_0000910	http://purl.obolibrary.org/obo/UPHENO_0083057
+http://purl.obolibrary.org/obo/GO_0031153	http://purl.obolibrary.org/obo/UPHENO_0083058
+http://purl.obolibrary.org/obo/GO_0031152	http://purl.obolibrary.org/obo/UPHENO_0083059
+http://purl.obolibrary.org/obo/GO_0051591	http://purl.obolibrary.org/obo/UPHENO_0083060
+http://purl.obolibrary.org/obo/GO_0090383	http://purl.obolibrary.org/obo/UPHENO_0083061
diff --git a/src/curation/upheno-fillers/ddpheno/abnormallyIncreasedEfficacyOfProteinLocalizationInCellularComponent.tsv b/src/curation/upheno-fillers/ddpheno/abnormallyIncreasedEfficacyOfProteinLocalizationInCellularComponent.tsv
new file mode 100644
index 00000000..5ad7fcec
--- /dev/null
+++ b/src/curation/upheno-fillers/ddpheno/abnormallyIncreasedEfficacyOfProteinLocalizationInCellularComponent.tsv
@@ -0,0 +1,33 @@
+location	defined_class
+http://purl.obolibrary.org/obo/GO_0031254	http://purl.obolibrary.org/obo/UPHENO_0083857
+http://purl.obolibrary.org/obo/GO_0031410	http://purl.obolibrary.org/obo/UPHENO_0083858
+http://purl.obolibrary.org/obo/GO_0005905	http://purl.obolibrary.org/obo/UPHENO_0083859
+http://purl.obolibrary.org/obo/GO_0031252	http://purl.obolibrary.org/obo/UPHENO_0083860
+http://purl.obolibrary.org/obo/GO_0072686	http://purl.obolibrary.org/obo/UPHENO_0083861
+http://purl.obolibrary.org/obo/GO_0062201	http://purl.obolibrary.org/obo/UPHENO_0083862
+http://purl.obolibrary.org/obo/GO_0009986	http://purl.obolibrary.org/obo/UPHENO_0083863
+http://purl.obolibrary.org/obo/GO_0044354	http://purl.obolibrary.org/obo/UPHENO_0083864
+http://purl.obolibrary.org/obo/GO_0000331	http://purl.obolibrary.org/obo/UPHENO_0083865
+http://purl.obolibrary.org/obo/GO_0005764	http://purl.obolibrary.org/obo/UPHENO_0083866
+http://purl.obolibrary.org/obo/GO_1990023	http://purl.obolibrary.org/obo/UPHENO_0083867
+http://purl.obolibrary.org/obo/GO_0005765	http://purl.obolibrary.org/obo/UPHENO_0083868
+http://purl.obolibrary.org/obo/GO_0005886	http://purl.obolibrary.org/obo/UPHENO_0083869
+http://purl.obolibrary.org/obo/GO_0044291	http://purl.obolibrary.org/obo/UPHENO_0083870
+http://purl.obolibrary.org/obo/GO_0005815	http://purl.obolibrary.org/obo/UPHENO_0083871
+http://purl.obolibrary.org/obo/GO_0031164	http://purl.obolibrary.org/obo/UPHENO_0083872
+http://purl.obolibrary.org/obo/GO_0005938	http://purl.obolibrary.org/obo/UPHENO_0083873
+http://purl.obolibrary.org/obo/GO_0032154	http://purl.obolibrary.org/obo/UPHENO_0083874
+http://purl.obolibrary.org/obo/GO_0030175	http://purl.obolibrary.org/obo/UPHENO_0083875
+http://purl.obolibrary.org/obo/GO_0031143	http://purl.obolibrary.org/obo/UPHENO_0083876
+http://purl.obolibrary.org/obo/GO_0032195	http://purl.obolibrary.org/obo/UPHENO_0083877
+http://purl.obolibrary.org/obo/GO_0036019	http://purl.obolibrary.org/obo/UPHENO_0083878
+http://purl.obolibrary.org/obo/GO_0016323	http://purl.obolibrary.org/obo/UPHENO_0083879
+http://purl.obolibrary.org/obo/GO_0045335	http://purl.obolibrary.org/obo/UPHENO_0083880
+http://purl.obolibrary.org/obo/GO_0005575	http://purl.obolibrary.org/obo/UPHENO_0083881
+http://purl.obolibrary.org/obo/GO_0005635	http://purl.obolibrary.org/obo/UPHENO_0083882
+http://purl.obolibrary.org/obo/GO_0005813	http://purl.obolibrary.org/obo/UPHENO_0083883
+http://purl.obolibrary.org/obo/GO_0005737	http://purl.obolibrary.org/obo/UPHENO_0083884
+http://purl.obolibrary.org/obo/GO_0005730	http://purl.obolibrary.org/obo/UPHENO_0083885
+http://purl.obolibrary.org/obo/GO_0005874	http://purl.obolibrary.org/obo/UPHENO_0083886
+http://purl.obolibrary.org/obo/GO_0005776	http://purl.obolibrary.org/obo/UPHENO_0083887
+http://purl.obolibrary.org/obo/GO_0005634	http://purl.obolibrary.org/obo/UPHENO_0083888
diff --git a/src/curation/upheno-fillers/ddpheno/abnormallyIncreasedLevelOfChemicalEntity.tsv b/src/curation/upheno-fillers/ddpheno/abnormallyIncreasedLevelOfChemicalEntity.tsv
new file mode 100644
index 00000000..0ef2d647
--- /dev/null
+++ b/src/curation/upheno-fillers/ddpheno/abnormallyIncreasedLevelOfChemicalEntity.tsv
@@ -0,0 +1,5 @@
+chemical_entity	defined_class
+http://purl.obolibrary.org/obo/CHEBI_36080	http://purl.obolibrary.org/obo/UPHENO_0082943
+http://purl.obolibrary.org/obo/CHEBI_15422	http://purl.obolibrary.org/obo/UPHENO_0075669
+http://purl.obolibrary.org/obo/CHEBI_24431	http://purl.obolibrary.org/obo/UPHENO_0048707
+http://purl.obolibrary.org/obo/CHEBI_16134	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/ddpheno/abnormallyIncreasedNumberOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/ddpheno/abnormallyIncreasedNumberOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..dbbb3ad6
--- /dev/null
+++ b/src/curation/upheno-fillers/ddpheno/abnormallyIncreasedNumberOfAnatomicalEntity.tsv
@@ -0,0 +1,8 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0014240
+http://purl.obolibrary.org/obo/GO_0005813	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0000331	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0005776	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0005815	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0005739	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0044352	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/ddpheno/abnormallyIncreasedNumberOfCellularComponent.tsv b/src/curation/upheno-fillers/ddpheno/abnormallyIncreasedNumberOfCellularComponent.tsv
new file mode 100644
index 00000000..252a74bb
--- /dev/null
+++ b/src/curation/upheno-fillers/ddpheno/abnormallyIncreasedNumberOfCellularComponent.tsv
@@ -0,0 +1,8 @@
+cellular_component	defined_class
+http://purl.obolibrary.org/obo/GO_0005815	http://purl.obolibrary.org/obo/UPHENO_0083032
+http://purl.obolibrary.org/obo/GO_0005739	http://purl.obolibrary.org/obo/UPHENO_0063670
+http://purl.obolibrary.org/obo/GO_0044352	http://purl.obolibrary.org/obo/UPHENO_0083033
+http://purl.obolibrary.org/obo/GO_0005575	http://purl.obolibrary.org/obo/UPHENO_0063672
+http://purl.obolibrary.org/obo/GO_0005776	http://purl.obolibrary.org/obo/UPHENO_0083034
+http://purl.obolibrary.org/obo/GO_0005813	http://purl.obolibrary.org/obo/UPHENO_0083035
+http://purl.obolibrary.org/obo/GO_0000331	http://purl.obolibrary.org/obo/UPHENO_0083036
diff --git a/src/curation/upheno-fillers/ddpheno/abnormallyIncreasedOccurrenceOfBiologicalProcess.tsv b/src/curation/upheno-fillers/ddpheno/abnormallyIncreasedOccurrenceOfBiologicalProcess.tsv
new file mode 100644
index 00000000..c7c47b5a
--- /dev/null
+++ b/src/curation/upheno-fillers/ddpheno/abnormallyIncreasedOccurrenceOfBiologicalProcess.tsv
@@ -0,0 +1,95 @@
+biological_process	defined_class
+http://purl.obolibrary.org/obo/GO_1902605	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0006974	http://purl.obolibrary.org/obo/UPHENO_0079318
+http://purl.obolibrary.org/obo/GO_0006412	http://purl.obolibrary.org/obo/UPHENO_0079256
+http://purl.obolibrary.org/obo/GO_0097300	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0007264	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0007265	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0007020	http://purl.obolibrary.org/obo/UPHENO_0083774
+http://purl.obolibrary.org/obo/GO_1903013	http://purl.obolibrary.org/obo/UPHENO_0083775
+http://purl.obolibrary.org/obo/GO_0140676	http://purl.obolibrary.org/obo/UPHENO_0083777
+http://purl.obolibrary.org/obo/GO_0042554	http://purl.obolibrary.org/obo/UPHENO_0083778
+http://purl.obolibrary.org/obo/GO_0043326	http://purl.obolibrary.org/obo/UPHENO_0083780
+http://purl.obolibrary.org/obo/GO_0043327	http://purl.obolibrary.org/obo/UPHENO_0083781
+http://purl.obolibrary.org/obo/GO_0120320	http://purl.obolibrary.org/obo/UPHENO_0083782
+http://purl.obolibrary.org/obo/GO_0016339	http://purl.obolibrary.org/obo/UPHENO_0083783
+http://purl.obolibrary.org/obo/GO_0031271	http://purl.obolibrary.org/obo/UPHENO_0083784
+http://purl.obolibrary.org/obo/GO_0006182	http://purl.obolibrary.org/obo/UPHENO_0083785
+http://purl.obolibrary.org/obo/GO_0016338	http://purl.obolibrary.org/obo/UPHENO_0083786
+http://purl.obolibrary.org/obo/GO_0035752	http://purl.obolibrary.org/obo/UPHENO_0083787
+http://purl.obolibrary.org/obo/GO_0043408	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0031154	http://purl.obolibrary.org/obo/UPHENO_0083788
+http://purl.obolibrary.org/obo/GO_0033299	http://purl.obolibrary.org/obo/UPHENO_0083789
+http://purl.obolibrary.org/obo/GO_0032482	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0031036	http://purl.obolibrary.org/obo/UPHENO_0083791
+http://purl.obolibrary.org/obo/GO_0032486	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0071456	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0006887	http://purl.obolibrary.org/obo/UPHENO_0083793
+http://purl.obolibrary.org/obo/GO_0051017	http://purl.obolibrary.org/obo/UPHENO_0083794
+http://purl.obolibrary.org/obo/GO_0097178	http://purl.obolibrary.org/obo/UPHENO_0083795
+http://purl.obolibrary.org/obo/GO_0000266	http://purl.obolibrary.org/obo/UPHENO_0083796
+http://purl.obolibrary.org/obo/GO_0070370	http://purl.obolibrary.org/obo/UPHENO_0083797
+http://purl.obolibrary.org/obo/GO_0008104	http://purl.obolibrary.org/obo/UPHENO_0083799
+http://purl.obolibrary.org/obo/GO_0010226	http://purl.obolibrary.org/obo/UPHENO_0083800
+http://purl.obolibrary.org/obo/GO_0042742	http://purl.obolibrary.org/obo/UPHENO_0081694
+http://purl.obolibrary.org/obo/GO_0010467	http://purl.obolibrary.org/obo/UPHENO_0081696
+http://purl.obolibrary.org/obo/GO_0016601	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0006171	http://purl.obolibrary.org/obo/UPHENO_0083803
+http://purl.obolibrary.org/obo/GO_0036211	http://purl.obolibrary.org/obo/UPHENO_0083804
+http://purl.obolibrary.org/obo/GO_0140042	http://purl.obolibrary.org/obo/UPHENO_0083805
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UPHENO_0079251
+http://purl.obolibrary.org/obo/GO_0051453	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0034670	http://purl.obolibrary.org/obo/UPHENO_0083806
+http://purl.obolibrary.org/obo/GO_0070177	http://purl.obolibrary.org/obo/UPHENO_0083807
+http://purl.obolibrary.org/obo/GO_0032456	http://purl.obolibrary.org/obo/UPHENO_0083809
+http://purl.obolibrary.org/obo/GO_0030154	http://purl.obolibrary.org/obo/UPHENO_0083811
+http://purl.obolibrary.org/obo/GO_0008219	http://purl.obolibrary.org/obo/UPHENO_0079408
+http://purl.obolibrary.org/obo/GO_0050832	http://purl.obolibrary.org/obo/UPHENO_0083812
+http://purl.obolibrary.org/obo/GO_0006914	http://purl.obolibrary.org/obo/UPHENO_0079458
+http://purl.obolibrary.org/obo/GO_0050830	http://purl.obolibrary.org/obo/UPHENO_0083813
+http://purl.obolibrary.org/obo/GO_0000012	http://purl.obolibrary.org/obo/UPHENO_0083814
+http://purl.obolibrary.org/obo/GO_0051641	http://purl.obolibrary.org/obo/UPHENO_0083815
+http://purl.obolibrary.org/obo/GO_0050919	http://purl.obolibrary.org/obo/UPHENO_0083817
+http://purl.obolibrary.org/obo/GO_1905146	http://purl.obolibrary.org/obo/UPHENO_0083818
+http://purl.obolibrary.org/obo/GO_0048870	http://purl.obolibrary.org/obo/UPHENO_0083819
+http://purl.obolibrary.org/obo/GO_0044351	http://purl.obolibrary.org/obo/UPHENO_0083820
+http://purl.obolibrary.org/obo/GO_0042330	http://purl.obolibrary.org/obo/UPHENO_0083821
+http://purl.obolibrary.org/obo/GO_0042331	http://purl.obolibrary.org/obo/UPHENO_0083822
+http://purl.obolibrary.org/obo/GO_0016236	http://purl.obolibrary.org/obo/UPHENO_0083823
+http://purl.obolibrary.org/obo/GO_0034446	http://purl.obolibrary.org/obo/UPHENO_0083825
+http://purl.obolibrary.org/obo/GO_0038203	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0032060	http://purl.obolibrary.org/obo/UPHENO_0079466
+http://purl.obolibrary.org/obo/GO_0071476	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0030042	http://purl.obolibrary.org/obo/UPHENO_0083826
+http://purl.obolibrary.org/obo/GO_0031054	http://purl.obolibrary.org/obo/UPHENO_0083827
+http://purl.obolibrary.org/obo/GO_0030041	http://purl.obolibrary.org/obo/UPHENO_0079358
+http://purl.obolibrary.org/obo/GO_0033275	http://purl.obolibrary.org/obo/UPHENO_0083828
+http://purl.obolibrary.org/obo/GO_0009306	http://purl.obolibrary.org/obo/UPHENO_0083830
+http://purl.obolibrary.org/obo/GO_0030244	http://purl.obolibrary.org/obo/UPHENO_0083831
+http://purl.obolibrary.org/obo/GO_0031589	http://purl.obolibrary.org/obo/UPHENO_0083832
+http://purl.obolibrary.org/obo/GO_0006303	http://purl.obolibrary.org/obo/UPHENO_0083833
+http://purl.obolibrary.org/obo/GO_0050821	http://purl.obolibrary.org/obo/UPHENO_0083834
+http://purl.obolibrary.org/obo/GO_0031148	http://purl.obolibrary.org/obo/UPHENO_0083835
+http://purl.obolibrary.org/obo/GO_0006302	http://purl.obolibrary.org/obo/UPHENO_0083836
+http://purl.obolibrary.org/obo/GO_0031269	http://purl.obolibrary.org/obo/UPHENO_0083837
+http://purl.obolibrary.org/obo/GO_0006826	http://purl.obolibrary.org/obo/UPHENO_0083838
+http://purl.obolibrary.org/obo/GO_0043491	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0043052	http://purl.obolibrary.org/obo/UPHENO_0083839
+http://purl.obolibrary.org/obo/GO_0048102	http://purl.obolibrary.org/obo/UPHENO_0083840
+http://purl.obolibrary.org/obo/GO_0050829	http://purl.obolibrary.org/obo/UPHENO_0083841
+http://purl.obolibrary.org/obo/GO_0045110	http://purl.obolibrary.org/obo/UPHENO_0083842
+http://purl.obolibrary.org/obo/GO_0140986	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0006661	http://purl.obolibrary.org/obo/UPHENO_0083843
+http://purl.obolibrary.org/obo/GO_0019934	http://purl.obolibrary.org/obo/UPHENO_0083844
+http://purl.obolibrary.org/obo/GO_0046847	http://purl.obolibrary.org/obo/UPHENO_0079423
+http://purl.obolibrary.org/obo/GO_0012501	http://purl.obolibrary.org/obo/UPHENO_0079367
+http://purl.obolibrary.org/obo/GO_0098609	http://purl.obolibrary.org/obo/UPHENO_0079424
+http://purl.obolibrary.org/obo/GO_0043934	http://purl.obolibrary.org/obo/UPHENO_0083846
+http://purl.obolibrary.org/obo/GO_0008053	http://purl.obolibrary.org/obo/UPHENO_0083847
+http://purl.obolibrary.org/obo/GO_0033562	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0030010	http://purl.obolibrary.org/obo/UPHENO_0083848
+http://purl.obolibrary.org/obo/GO_0006907	http://purl.obolibrary.org/obo/UPHENO_0083849
+http://purl.obolibrary.org/obo/GO_0034058	http://purl.obolibrary.org/obo/UPHENO_0083850
+http://purl.obolibrary.org/obo/GO_0000724	http://purl.obolibrary.org/obo/UPHENO_0083851
+http://purl.obolibrary.org/obo/GO_0051591	http://purl.obolibrary.org/obo/UPHENO_0083852
+http://purl.obolibrary.org/obo/GO_0006909	http://purl.obolibrary.org/obo/UPHENO_0083853
diff --git a/src/curation/upheno-fillers/ddpheno/abnormallyIncreasedRateOfBiologicalProcess.tsv b/src/curation/upheno-fillers/ddpheno/abnormallyIncreasedRateOfBiologicalProcess.tsv
new file mode 100644
index 00000000..02702079
--- /dev/null
+++ b/src/curation/upheno-fillers/ddpheno/abnormallyIncreasedRateOfBiologicalProcess.tsv
@@ -0,0 +1,5 @@
+biological_process	defined_class
+http://purl.obolibrary.org/obo/GO_0019954	http://purl.obolibrary.org/obo/UPHENO_0084229
+http://purl.obolibrary.org/obo/GO_0006897	http://purl.obolibrary.org/obo/UPHENO_0084230
+http://purl.obolibrary.org/obo/GO_0006935	http://purl.obolibrary.org/obo/UPHENO_0055236
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UPHENO_0054970
diff --git a/src/curation/upheno-fillers/ddpheno/abnormallyIncreasedRateOfMolecularFunction.tsv b/src/curation/upheno-fillers/ddpheno/abnormallyIncreasedRateOfMolecularFunction.tsv
new file mode 100644
index 00000000..e8925250
--- /dev/null
+++ b/src/curation/upheno-fillers/ddpheno/abnormallyIncreasedRateOfMolecularFunction.tsv
@@ -0,0 +1,22 @@
+molecular_function	defined_class
+http://purl.obolibrary.org/obo/GO_0005096	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0004096	http://purl.obolibrary.org/obo/UPHENO_0048668
+http://purl.obolibrary.org/obo/GO_0005085	http://purl.obolibrary.org/obo/UPHENO_0083282
+http://purl.obolibrary.org/obo/GO_0004383	http://purl.obolibrary.org/obo/UPHENO_0083283
+http://purl.obolibrary.org/obo/GO_0047555	http://purl.obolibrary.org/obo/UPHENO_0083284
+http://purl.obolibrary.org/obo/GO_0004672	http://purl.obolibrary.org/obo/UPHENO_0083285
+http://purl.obolibrary.org/obo/GO_0045499	http://purl.obolibrary.org/obo/UPHENO_0083286
+http://purl.obolibrary.org/obo/GO_0005542	http://purl.obolibrary.org/obo/UPHENO_0083287
+http://purl.obolibrary.org/obo/GO_0004115	http://purl.obolibrary.org/obo/UPHENO_0083288
+http://purl.obolibrary.org/obo/GO_0004016	http://purl.obolibrary.org/obo/UPHENO_0083289
+http://purl.obolibrary.org/obo/GO_0031545	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0003674	http://purl.obolibrary.org/obo/UPHENO_0048661
+http://purl.obolibrary.org/obo/GO_0005515	http://purl.obolibrary.org/obo/UPHENO_0083290
+http://purl.obolibrary.org/obo/GO_0004713	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0004725	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0004129	http://purl.obolibrary.org/obo/UPHENO_0083291
+http://purl.obolibrary.org/obo/GO_0016791	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0003824	http://purl.obolibrary.org/obo/UPHENO_0048683
+http://purl.obolibrary.org/obo/GO_0004407	http://purl.obolibrary.org/obo/UPHENO_0083292
+http://purl.obolibrary.org/obo/GO_0030552	http://purl.obolibrary.org/obo/UPHENO_0083293
+http://purl.obolibrary.org/obo/GO_0019887	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/ddpheno/abnormallyIncreasedSizeOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/ddpheno/abnormallyIncreasedSizeOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..18515cf3
--- /dev/null
+++ b/src/curation/upheno-fillers/ddpheno/abnormallyIncreasedSizeOfAnatomicalEntity.tsv
@@ -0,0 +1,8 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0001072
+http://purl.obolibrary.org/obo/GO_0032195	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0000331	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0005768	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0005764	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0031143	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0032010	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/ddpheno/abnormallyIncreasedSizeOfCellularComponent.tsv b/src/curation/upheno-fillers/ddpheno/abnormallyIncreasedSizeOfCellularComponent.tsv
new file mode 100644
index 00000000..a137ee6f
--- /dev/null
+++ b/src/curation/upheno-fillers/ddpheno/abnormallyIncreasedSizeOfCellularComponent.tsv
@@ -0,0 +1,8 @@
+entity	defined_class
+http://purl.obolibrary.org/obo/GO_0032010	http://purl.obolibrary.org/obo/UPHENO_0082991
+http://purl.obolibrary.org/obo/GO_0031143	http://purl.obolibrary.org/obo/UPHENO_0082992
+http://purl.obolibrary.org/obo/GO_0005575	http://purl.obolibrary.org/obo/UPHENO_0080309
+http://purl.obolibrary.org/obo/GO_0005764	http://purl.obolibrary.org/obo/UPHENO_0082993
+http://purl.obolibrary.org/obo/GO_0005768	http://purl.obolibrary.org/obo/UPHENO_0082994
+http://purl.obolibrary.org/obo/GO_0032195	http://purl.obolibrary.org/obo/UPHENO_0082995
+http://purl.obolibrary.org/obo/GO_0000331	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/ddpheno/abnormallyPrematureBiologicalProcess.tsv b/src/curation/upheno-fillers/ddpheno/abnormallyPrematureBiologicalProcess.tsv
new file mode 100644
index 00000000..6a4328df
--- /dev/null
+++ b/src/curation/upheno-fillers/ddpheno/abnormallyPrematureBiologicalProcess.tsv
@@ -0,0 +1,14 @@
+biological_process	defined_class
+http://purl.obolibrary.org/obo/GO_0030587	http://purl.obolibrary.org/obo/UPHENO_0083018
+http://purl.obolibrary.org/obo/GO_0000022	http://purl.obolibrary.org/obo/UPHENO_0083019
+http://purl.obolibrary.org/obo/GO_1903013	http://purl.obolibrary.org/obo/UPHENO_0083020
+http://purl.obolibrary.org/obo/GO_0006972	http://purl.obolibrary.org/obo/UPHENO_0083021
+http://purl.obolibrary.org/obo/GO_0006971	http://purl.obolibrary.org/obo/UPHENO_0083022
+http://purl.obolibrary.org/obo/GO_0010467	http://purl.obolibrary.org/obo/UPHENO_0083023
+http://purl.obolibrary.org/obo/GO_0043934	http://purl.obolibrary.org/obo/UPHENO_0083024
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UPHENO_0049440
+http://purl.obolibrary.org/obo/GO_0031154	http://purl.obolibrary.org/obo/UPHENO_0083025
+http://purl.obolibrary.org/obo/GO_0031152	http://purl.obolibrary.org/obo/UPHENO_0083026
+http://purl.obolibrary.org/obo/GO_0070177	http://purl.obolibrary.org/obo/UPHENO_0083027
+http://purl.obolibrary.org/obo/GO_0009847	http://purl.obolibrary.org/obo/UPHENO_0083028
+http://purl.obolibrary.org/obo/GO_0090383	http://purl.obolibrary.org/obo/UPHENO_0083029
diff --git a/src/curation/upheno-fillers/dpo/abnormalAbsenceOfBiologicalProcess.tsv b/src/curation/upheno-fillers/dpo/abnormalAbsenceOfBiologicalProcess.tsv
new file mode 100644
index 00000000..e4061324
--- /dev/null
+++ b/src/curation/upheno-fillers/dpo/abnormalAbsenceOfBiologicalProcess.tsv
@@ -0,0 +1,4 @@
+biological_process	defined_class
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UPHENO_0034024
+http://purl.obolibrary.org/obo/GO_0060361	http://purl.obolibrary.org/obo/UPHENO_0078503
+http://purl.obolibrary.org/obo/GO_0050879	http://purl.obolibrary.org/obo/UPHENO_0078504
diff --git a/src/curation/upheno-fillers/dpo/abnormalAnatomicalEntity.tsv b/src/curation/upheno-fillers/dpo/abnormalAnatomicalEntity.tsv
new file mode 100644
index 00000000..ebe14380
--- /dev/null
+++ b/src/curation/upheno-fillers/dpo/abnormalAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0002536
diff --git a/src/curation/upheno-fillers/dpo/abnormalBiologicalProcess.tsv b/src/curation/upheno-fillers/dpo/abnormalBiologicalProcess.tsv
new file mode 100644
index 00000000..a70f8bfc
--- /dev/null
+++ b/src/curation/upheno-fillers/dpo/abnormalBiologicalProcess.tsv
@@ -0,0 +1,71 @@
+biological_process	defined_class
+http://purl.obolibrary.org/obo/GO_0007625	http://purl.obolibrary.org/obo/UPHENO_0078680
+http://purl.obolibrary.org/obo/GO_0000278	http://purl.obolibrary.org/obo/UPHENO_0050313
+http://purl.obolibrary.org/obo/GO_0050975	http://purl.obolibrary.org/obo/UPHENO_0050208
+http://purl.obolibrary.org/obo/GO_0007623	http://purl.obolibrary.org/obo/UPHENO_0049593
+http://purl.obolibrary.org/obo/GO_0007628	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0006979	http://purl.obolibrary.org/obo/UPHENO_0049674
+http://purl.obolibrary.org/obo/GO_0007626	http://purl.obolibrary.org/obo/UPHENO_0050571
+http://purl.obolibrary.org/obo/GO_0060361	http://purl.obolibrary.org/obo/UPHENO_0078681
+http://purl.obolibrary.org/obo/GO_0042594	http://purl.obolibrary.org/obo/UPHENO_0049906
+http://purl.obolibrary.org/obo/GO_0007620	http://purl.obolibrary.org/obo/UPHENO_0049597
+http://purl.obolibrary.org/obo/GO_0006970	http://purl.obolibrary.org/obo/UPHENO_0049681
+http://purl.obolibrary.org/obo/GO_0009409	http://purl.obolibrary.org/obo/UPHENO_0078682
+http://purl.obolibrary.org/obo/GO_0000910	http://purl.obolibrary.org/obo/UPHENO_0050076
+http://purl.obolibrary.org/obo/GO_0009408	http://purl.obolibrary.org/obo/UPHENO_0049999
+http://purl.obolibrary.org/obo/GO_0018991	http://purl.obolibrary.org/obo/UPHENO_0049603
+http://purl.obolibrary.org/obo/GO_0048060	http://purl.obolibrary.org/obo/UPHENO_0078683
+http://purl.obolibrary.org/obo/GO_0007613	http://purl.obolibrary.org/obo/UPHENO_0050579
+http://purl.obolibrary.org/obo/GO_0007614	http://purl.obolibrary.org/obo/UPHENO_0080607
+http://purl.obolibrary.org/obo/GO_0007612	http://purl.obolibrary.org/obo/UPHENO_0049612
+http://purl.obolibrary.org/obo/GO_0007617	http://purl.obolibrary.org/obo/UPHENO_0049614
+http://purl.obolibrary.org/obo/GO_0007618	http://purl.obolibrary.org/obo/UPHENO_0049615
+http://purl.obolibrary.org/obo/GO_0042060	http://purl.obolibrary.org/obo/UPHENO_0050846
+http://purl.obolibrary.org/obo/GO_0007615	http://purl.obolibrary.org/obo/UPHENO_0080608
+http://purl.obolibrary.org/obo/GO_0007616	http://purl.obolibrary.org/obo/UPHENO_0080609
+http://purl.obolibrary.org/obo/GO_0043153	http://purl.obolibrary.org/obo/UPHENO_0078684
+http://purl.obolibrary.org/obo/GO_0035648	http://purl.obolibrary.org/obo/UPHENO_0078685
+http://purl.obolibrary.org/obo/GO_0007610	http://purl.obolibrary.org/obo/UPHENO_0049622
+http://purl.obolibrary.org/obo/GO_0008344	http://purl.obolibrary.org/obo/UPHENO_0051428
+http://purl.obolibrary.org/obo/GO_0007530	http://purl.obolibrary.org/obo/UPHENO_0050096
+http://purl.obolibrary.org/obo/GO_0008345	http://purl.obolibrary.org/obo/UPHENO_0051430
+http://purl.obolibrary.org/obo/GO_0016049	http://purl.obolibrary.org/obo/UPHENO_0050012
+http://purl.obolibrary.org/obo/GO_0009950	http://purl.obolibrary.org/obo/UPHENO_0050167
+http://purl.obolibrary.org/obo/GO_0009798	http://purl.obolibrary.org/obo/UPHENO_0050169
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UPHENO_0049587
+http://purl.obolibrary.org/obo/GO_0007619	http://purl.obolibrary.org/obo/UPHENO_0078667
+http://purl.obolibrary.org/obo/GO_0030431	http://purl.obolibrary.org/obo/UPHENO_0050855
+http://purl.obolibrary.org/obo/GO_0008219	http://purl.obolibrary.org/obo/UPHENO_0050027
+http://purl.obolibrary.org/obo/GO_0007600	http://purl.obolibrary.org/obo/UPHENO_0050620
+http://purl.obolibrary.org/obo/GO_0050953	http://purl.obolibrary.org/obo/UPHENO_0050236
+http://purl.obolibrary.org/obo/GO_0007605	http://purl.obolibrary.org/obo/UPHENO_0050625
+http://purl.obolibrary.org/obo/GO_0006955	http://purl.obolibrary.org/obo/UPHENO_0049759
+http://purl.obolibrary.org/obo/GO_0048512	http://purl.obolibrary.org/obo/UPHENO_0049633
+http://purl.obolibrary.org/obo/GO_0007562	http://purl.obolibrary.org/obo/UPHENO_0078686
+http://purl.obolibrary.org/obo/GO_0042331	http://purl.obolibrary.org/obo/UPHENO_0051095
+http://purl.obolibrary.org/obo/GO_0006950	http://purl.obolibrary.org/obo/UPHENO_0049588
+http://purl.obolibrary.org/obo/GO_0007049	http://purl.obolibrary.org/obo/UPHENO_0049952
+http://purl.obolibrary.org/obo/GO_0016477	http://purl.obolibrary.org/obo/UPHENO_0049643
+http://purl.obolibrary.org/obo/GO_0006281	http://purl.obolibrary.org/obo/UPHENO_0051124
+http://purl.obolibrary.org/obo/GO_0008062	http://purl.obolibrary.org/obo/UPHENO_0078687
+http://purl.obolibrary.org/obo/GO_0050909	http://purl.obolibrary.org/obo/UPHENO_0078688
+http://purl.obolibrary.org/obo/GO_0009266	http://purl.obolibrary.org/obo/UPHENO_0049885
+http://purl.obolibrary.org/obo/GO_0051321	http://purl.obolibrary.org/obo/UPHENO_0078653
+http://purl.obolibrary.org/obo/GO_0007608	http://purl.obolibrary.org/obo/UPHENO_0078689
+http://purl.obolibrary.org/obo/GO_0007635	http://purl.obolibrary.org/obo/UPHENO_0049648
+http://purl.obolibrary.org/obo/GO_0007634	http://purl.obolibrary.org/obo/UPHENO_0050588
+http://purl.obolibrary.org/obo/GO_0048265	http://purl.obolibrary.org/obo/UPHENO_0078690
+http://purl.obolibrary.org/obo/GO_0072375	http://purl.obolibrary.org/obo/UPHENO_0080610
+http://purl.obolibrary.org/obo/GO_0007637	http://purl.obolibrary.org/obo/UPHENO_0078691
+http://purl.obolibrary.org/obo/GO_0043052	http://purl.obolibrary.org/obo/UPHENO_0049656
+http://purl.obolibrary.org/obo/GO_0007155	http://purl.obolibrary.org/obo/UPHENO_0049969
+http://purl.obolibrary.org/obo/GO_0045475	http://purl.obolibrary.org/obo/UPHENO_0050594
+http://purl.obolibrary.org/obo/GO_0007631	http://purl.obolibrary.org/obo/UPHENO_0049664
+http://purl.obolibrary.org/obo/GO_0007632	http://purl.obolibrary.org/obo/UPHENO_0050596
+http://purl.obolibrary.org/obo/GO_0007113	http://purl.obolibrary.org/obo/UPHENO_0078692
+http://purl.obolibrary.org/obo/GO_0007630	http://purl.obolibrary.org/obo/UPHENO_0078693
+http://purl.obolibrary.org/obo/GO_0045433	http://purl.obolibrary.org/obo/UPHENO_0078694
+http://purl.obolibrary.org/obo/GO_0035187	http://purl.obolibrary.org/obo/UPHENO_0078695
+http://purl.obolibrary.org/obo/GO_0001736	http://purl.obolibrary.org/obo/UPHENO_0078678
+http://purl.obolibrary.org/obo/GO_0055116	http://purl.obolibrary.org/obo/UPHENO_0078696
+http://purl.obolibrary.org/obo/GO_0055115	http://purl.obolibrary.org/obo/UPHENO_0050136
diff --git a/src/curation/upheno-fillers/dpo/abnormalNumberOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/dpo/abnormalNumberOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..439cb46b
--- /dev/null
+++ b/src/curation/upheno-fillers/dpo/abnormalNumberOfAnatomicalEntity.tsv
@@ -0,0 +1,3 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0011498
+http://purl.obolibrary.org/obo/CL_0000000	http://purl.obolibrary.org/obo/UPHENO_0077426
diff --git a/src/curation/upheno-fillers/dpo/abnormalPigmentationOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/dpo/abnormalPigmentationOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..9043ea08
--- /dev/null
+++ b/src/curation/upheno-fillers/dpo/abnormalPigmentationOfAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0066794
diff --git a/src/curation/upheno-fillers/dpo/abnormalShapeOfAnatomicalEntityByShapeType.tsv b/src/curation/upheno-fillers/dpo/abnormalShapeOfAnatomicalEntityByShapeType.tsv
new file mode 100644
index 00000000..110d211f
--- /dev/null
+++ b/src/curation/upheno-fillers/dpo/abnormalShapeOfAnatomicalEntityByShapeType.tsv
@@ -0,0 +1 @@
+entity	shape	defined_class
diff --git a/src/curation/upheno-fillers/dpo/abnormalShapeOfPhysicalEntity.tsv b/src/curation/upheno-fillers/dpo/abnormalShapeOfPhysicalEntity.tsv
new file mode 100644
index 00000000..458b13e3
--- /dev/null
+++ b/src/curation/upheno-fillers/dpo/abnormalShapeOfPhysicalEntity.tsv
@@ -0,0 +1,3 @@
+entity	defined_class
+http://purl.obolibrary.org/obo/BFO_0000002	http://purl.obolibrary.org/obo/UPHENO_0080300
+http://purl.obolibrary.org/obo/CL_0000000	http://purl.obolibrary.org/obo/UPHENO_0077197
diff --git a/src/curation/upheno-fillers/dpo/abnormalSizeOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/dpo/abnormalSizeOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..153d92c3
--- /dev/null
+++ b/src/curation/upheno-fillers/dpo/abnormalSizeOfAnatomicalEntity.tsv
@@ -0,0 +1,3 @@
+entity	defined_class
+http://purl.obolibrary.org/obo/CL_0000000	http://purl.obolibrary.org/obo/UPHENO_0077801
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0075195
diff --git a/src/curation/upheno-fillers/dpo/abnormalWeightOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/dpo/abnormalWeightOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..e1eff1cc
--- /dev/null
+++ b/src/curation/upheno-fillers/dpo/abnormalWeightOfAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0010763
diff --git a/src/curation/upheno-fillers/dpo/abnormallyDecreasedMassOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/dpo/abnormallyDecreasedMassOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..a9eec4ec
--- /dev/null
+++ b/src/curation/upheno-fillers/dpo/abnormallyDecreasedMassOfAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0082761
diff --git a/src/curation/upheno-fillers/dpo/abnormallyDecreasedNumberOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/dpo/abnormallyDecreasedNumberOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..8c1f8569
--- /dev/null
+++ b/src/curation/upheno-fillers/dpo/abnormallyDecreasedNumberOfAnatomicalEntity.tsv
@@ -0,0 +1,3 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0063722
+http://purl.obolibrary.org/obo/CL_0000000	http://purl.obolibrary.org/obo/UPHENO_0076675
diff --git a/src/curation/upheno-fillers/dpo/abnormallyDecreasedOccurrenceOfBiologicalProcess.tsv b/src/curation/upheno-fillers/dpo/abnormallyDecreasedOccurrenceOfBiologicalProcess.tsv
new file mode 100644
index 00000000..a43d4da1
--- /dev/null
+++ b/src/curation/upheno-fillers/dpo/abnormallyDecreasedOccurrenceOfBiologicalProcess.tsv
@@ -0,0 +1,4 @@
+biological_process	defined_class
+http://purl.obolibrary.org/obo/GO_0008219	http://purl.obolibrary.org/obo/UPHENO_0082838
+http://purl.obolibrary.org/obo/GO_0051301	http://purl.obolibrary.org/obo/UPHENO_0077434
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UPHENO_0077429
diff --git a/src/curation/upheno-fillers/dpo/abnormallyDecreasedRateOfBiologicalProcess.tsv b/src/curation/upheno-fillers/dpo/abnormallyDecreasedRateOfBiologicalProcess.tsv
new file mode 100644
index 00000000..afc1fbb1
--- /dev/null
+++ b/src/curation/upheno-fillers/dpo/abnormallyDecreasedRateOfBiologicalProcess.tsv
@@ -0,0 +1,20 @@
+biological_process	defined_class
+http://purl.obolibrary.org/obo/GO_0007635	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0007625	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0007628	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0007617	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0007629	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0007626	http://purl.obolibrary.org/obo/UPHENO_0005678
+http://purl.obolibrary.org/obo/GO_0007637	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0007155	http://purl.obolibrary.org/obo/UPHENO_0080289
+http://purl.obolibrary.org/obo/GO_0007620	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0007631	http://purl.obolibrary.org/obo/UPHENO_0005673
+http://purl.obolibrary.org/obo/GO_0042331	http://purl.obolibrary.org/obo/UPHENO_0080290
+http://purl.obolibrary.org/obo/GO_0008344	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0007630	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0008345	http://purl.obolibrary.org/obo/UPHENO_0005781
+http://purl.obolibrary.org/obo/GO_0050879	http://purl.obolibrary.org/obo/UPHENO_0005521
+http://purl.obolibrary.org/obo/GO_0016049	http://purl.obolibrary.org/obo/UPHENO_0076903
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UPHENO_0005433
+http://purl.obolibrary.org/obo/GO_0007619	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0030431	http://purl.obolibrary.org/obo/UPHENO_0005595
diff --git a/src/curation/upheno-fillers/dpo/abnormallyDecreasedResistanceOfWholeOrganismToChemicalEntity.tsv b/src/curation/upheno-fillers/dpo/abnormallyDecreasedResistanceOfWholeOrganismToChemicalEntity.tsv
new file mode 100644
index 00000000..43396654
--- /dev/null
+++ b/src/curation/upheno-fillers/dpo/abnormallyDecreasedResistanceOfWholeOrganismToChemicalEntity.tsv
@@ -0,0 +1 @@
+chemical_entity	defined_class
diff --git a/src/curation/upheno-fillers/dpo/abnormallyDecreasedResistanceOfWholeOrganismToEntity.tsv b/src/curation/upheno-fillers/dpo/abnormallyDecreasedResistanceOfWholeOrganismToEntity.tsv
new file mode 100644
index 00000000..f8df8dee
--- /dev/null
+++ b/src/curation/upheno-fillers/dpo/abnormallyDecreasedResistanceOfWholeOrganismToEntity.tsv
@@ -0,0 +1,3 @@
+entity	defined_class
+http://purl.obolibrary.org/obo/BFO_0000001	http://purl.obolibrary.org/obo/UPHENO_0081418
+http://purl.obolibrary.org/obo/CHEBI_24431	http://purl.obolibrary.org/obo/UPHENO_0076053
diff --git a/src/curation/upheno-fillers/dpo/abnormallyDecreasedSizeOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/dpo/abnormallyDecreasedSizeOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..e00b06a8
--- /dev/null
+++ b/src/curation/upheno-fillers/dpo/abnormallyDecreasedSizeOfAnatomicalEntity.tsv
@@ -0,0 +1,3 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0068971
+http://purl.obolibrary.org/obo/CL_0000000	http://purl.obolibrary.org/obo/UPHENO_0080059
diff --git a/src/curation/upheno-fillers/dpo/abnormallyDecreasedWeightOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/dpo/abnormallyDecreasedWeightOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..3234483e
--- /dev/null
+++ b/src/curation/upheno-fillers/dpo/abnormallyDecreasedWeightOfAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0054261
diff --git a/src/curation/upheno-fillers/dpo/abnormallyIncreasedNumberOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/dpo/abnormallyIncreasedNumberOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..ea1ba015
--- /dev/null
+++ b/src/curation/upheno-fillers/dpo/abnormallyIncreasedNumberOfAnatomicalEntity.tsv
@@ -0,0 +1,3 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0014240
+http://purl.obolibrary.org/obo/CL_0000000	http://purl.obolibrary.org/obo/UPHENO_0079539
diff --git a/src/curation/upheno-fillers/dpo/abnormallyIncreasedOccurrenceOfBiologicalProcess.tsv b/src/curation/upheno-fillers/dpo/abnormallyIncreasedOccurrenceOfBiologicalProcess.tsv
new file mode 100644
index 00000000..d5d0f575
--- /dev/null
+++ b/src/curation/upheno-fillers/dpo/abnormallyIncreasedOccurrenceOfBiologicalProcess.tsv
@@ -0,0 +1,4 @@
+biological_process	defined_class
+http://purl.obolibrary.org/obo/GO_0008219	http://purl.obolibrary.org/obo/UPHENO_0079408
+http://purl.obolibrary.org/obo/GO_0051301	http://purl.obolibrary.org/obo/UPHENO_0079253
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UPHENO_0079251
diff --git a/src/curation/upheno-fillers/dpo/abnormallyIncreasedRateOfBiologicalProcess.tsv b/src/curation/upheno-fillers/dpo/abnormallyIncreasedRateOfBiologicalProcess.tsv
new file mode 100644
index 00000000..7ee5807f
--- /dev/null
+++ b/src/curation/upheno-fillers/dpo/abnormallyIncreasedRateOfBiologicalProcess.tsv
@@ -0,0 +1,20 @@
+biological_process	defined_class
+http://purl.obolibrary.org/obo/GO_0007635	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0007625	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0007628	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0007617	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0007629	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0007626	http://purl.obolibrary.org/obo/UPHENO_0055154
+http://purl.obolibrary.org/obo/GO_0007637	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0007155	http://purl.obolibrary.org/obo/UPHENO_0082829
+http://purl.obolibrary.org/obo/GO_0007620	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0007631	http://purl.obolibrary.org/obo/UPHENO_0055147
+http://purl.obolibrary.org/obo/GO_0042331	http://purl.obolibrary.org/obo/UPHENO_0082830
+http://purl.obolibrary.org/obo/GO_0008344	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0007630	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0008345	http://purl.obolibrary.org/obo/UPHENO_0055205
+http://purl.obolibrary.org/obo/GO_0050879	http://purl.obolibrary.org/obo/UPHENO_0076681
+http://purl.obolibrary.org/obo/GO_0016049	http://purl.obolibrary.org/obo/UPHENO_0076679
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UPHENO_0054970
+http://purl.obolibrary.org/obo/GO_0007619	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0030431	http://purl.obolibrary.org/obo/UPHENO_0055061
diff --git a/src/curation/upheno-fillers/dpo/abnormallyIncreasedResistanceOfWholeOrganismToChemicalEntity.tsv b/src/curation/upheno-fillers/dpo/abnormallyIncreasedResistanceOfWholeOrganismToChemicalEntity.tsv
new file mode 100644
index 00000000..43396654
--- /dev/null
+++ b/src/curation/upheno-fillers/dpo/abnormallyIncreasedResistanceOfWholeOrganismToChemicalEntity.tsv
@@ -0,0 +1 @@
+chemical_entity	defined_class
diff --git a/src/curation/upheno-fillers/dpo/abnormallyIncreasedResistanceOfWholeOrganismToEntity.tsv b/src/curation/upheno-fillers/dpo/abnormallyIncreasedResistanceOfWholeOrganismToEntity.tsv
new file mode 100644
index 00000000..5661b6c4
--- /dev/null
+++ b/src/curation/upheno-fillers/dpo/abnormallyIncreasedResistanceOfWholeOrganismToEntity.tsv
@@ -0,0 +1,3 @@
+entity	defined_class
+http://purl.obolibrary.org/obo/BFO_0000001	http://purl.obolibrary.org/obo/UPHENO_0082030
+http://purl.obolibrary.org/obo/CHEBI_24431	http://purl.obolibrary.org/obo/UPHENO_0078764
diff --git a/src/curation/upheno-fillers/dpo/abnormallyIncreasedSizeOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/dpo/abnormallyIncreasedSizeOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..77cb38de
--- /dev/null
+++ b/src/curation/upheno-fillers/dpo/abnormallyIncreasedSizeOfAnatomicalEntity.tsv
@@ -0,0 +1,3 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0001072
+http://purl.obolibrary.org/obo/CL_0000000	http://purl.obolibrary.org/obo/UPHENO_0076936
diff --git a/src/curation/upheno-fillers/dpo/abnormallyIncreasedWeightOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/dpo/abnormallyIncreasedWeightOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..f603c0cf
--- /dev/null
+++ b/src/curation/upheno-fillers/dpo/abnormallyIncreasedWeightOfAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0008273
diff --git a/src/curation/upheno-fillers/dpo/atrophiedAnatomicalEntity.tsv b/src/curation/upheno-fillers/dpo/atrophiedAnatomicalEntity.tsv
new file mode 100644
index 00000000..fc7fbf01
--- /dev/null
+++ b/src/curation/upheno-fillers/dpo/atrophiedAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0013936
diff --git a/src/curation/upheno-fillers/dpo/hyperplasticAnatomicalEntity.tsv b/src/curation/upheno-fillers/dpo/hyperplasticAnatomicalEntity.tsv
new file mode 100644
index 00000000..0e2c837a
--- /dev/null
+++ b/src/curation/upheno-fillers/dpo/hyperplasticAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0083530
diff --git a/src/curation/upheno-fillers/dpo/hypoplasticAnatomicalEntity.tsv b/src/curation/upheno-fillers/dpo/hypoplasticAnatomicalEntity.tsv
new file mode 100644
index 00000000..e31fa94a
--- /dev/null
+++ b/src/curation/upheno-fillers/dpo/hypoplasticAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0081091
diff --git a/src/curation/upheno-fillers/dpo/neoplasticAnatomicalEntity.tsv b/src/curation/upheno-fillers/dpo/neoplasticAnatomicalEntity.tsv
new file mode 100644
index 00000000..6cc392b9
--- /dev/null
+++ b/src/curation/upheno-fillers/dpo/neoplasticAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0081769
diff --git a/src/curation/upheno-fillers/fypo/abnormalAnatomicalEntity-modified.tsv b/src/curation/upheno-fillers/fypo/abnormalAnatomicalEntity-modified.tsv
new file mode 100644
index 00000000..8b09cee6
--- /dev/null
+++ b/src/curation/upheno-fillers/fypo/abnormalAnatomicalEntity-modified.tsv
@@ -0,0 +1,3 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0072687	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/fypo/abnormalAnatomicalEntityNotParts.tsv b/src/curation/upheno-fillers/fypo/abnormalAnatomicalEntityNotParts.tsv
new file mode 100644
index 00000000..43cb589e
--- /dev/null
+++ b/src/curation/upheno-fillers/fypo/abnormalAnatomicalEntityNotParts.tsv
@@ -0,0 +1,10 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0075696
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0075696
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0075696
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0075696
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0075696
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0075696
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0075696
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0075696
+http://purl.obolibrary.org/obo/GO_0072687	http://purl.obolibrary.org/obo/UPHENO_0087318
diff --git a/src/curation/upheno-fillers/fypo/abnormalCellularComponent-modified.tsv b/src/curation/upheno-fillers/fypo/abnormalCellularComponent-modified.tsv
new file mode 100644
index 00000000..4f4e1cd5
--- /dev/null
+++ b/src/curation/upheno-fillers/fypo/abnormalCellularComponent-modified.tsv
@@ -0,0 +1,3 @@
+cellular_component	defined_class
+http://purl.obolibrary.org/obo/GO_0072687	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0005575	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/fypo/abnormalLengthOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/fypo/abnormalLengthOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..2bf125a3
--- /dev/null
+++ b/src/curation/upheno-fillers/fypo/abnormalLengthOfAnatomicalEntity.tsv
@@ -0,0 +1,3 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0000781	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/fypo/abnormalMorphologyOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/fypo/abnormalMorphologyOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..2effeac1
--- /dev/null
+++ b/src/curation/upheno-fillers/fypo/abnormalMorphologyOfAnatomicalEntity.tsv
@@ -0,0 +1,154 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
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+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
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+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
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+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/GO_0009277	http://purl.obolibrary.org/obo/UPHENO_0085922
+http://purl.obolibrary.org/obo/GO_0015630	http://purl.obolibrary.org/obo/UPHENO_0085614
+http://purl.obolibrary.org/obo/CL_0000596	http://purl.obolibrary.org/obo/UPHENO_0085923
+http://purl.obolibrary.org/obo/CL_0000521	http://purl.obolibrary.org/obo/UPHENO_0085924
+http://purl.obolibrary.org/obo/GO_0005819	http://purl.obolibrary.org/obo/UPHENO_0085925
+http://purl.obolibrary.org/obo/GO_0005619	http://purl.obolibrary.org/obo/UPHENO_0085926
+http://purl.obolibrary.org/obo/GO_0005938	http://purl.obolibrary.org/obo/UPHENO_0085927
+http://purl.obolibrary.org/obo/GO_0005937	http://purl.obolibrary.org/obo/UPHENO_0085928
+http://purl.obolibrary.org/obo/GO_0005816	http://purl.obolibrary.org/obo/UPHENO_0085929
+http://purl.obolibrary.org/obo/GO_0030998	http://purl.obolibrary.org/obo/UPHENO_0085930
+http://purl.obolibrary.org/obo/GO_0000781	http://purl.obolibrary.org/obo/UPHENO_0085870
+http://purl.obolibrary.org/obo/GO_0000781	http://purl.obolibrary.org/obo/UPHENO_0085870
+http://purl.obolibrary.org/obo/GO_0005856	http://purl.obolibrary.org/obo/UPHENO_0085593
+http://purl.obolibrary.org/obo/GO_0000776	http://purl.obolibrary.org/obo/UPHENO_0085931
+http://purl.obolibrary.org/obo/GO_0005634	http://purl.obolibrary.org/obo/UPHENO_0077863
+http://purl.obolibrary.org/obo/GO_0005634	http://purl.obolibrary.org/obo/UPHENO_0077863
+http://purl.obolibrary.org/obo/GO_0005634	http://purl.obolibrary.org/obo/UPHENO_0077863
+http://purl.obolibrary.org/obo/GO_0005634	http://purl.obolibrary.org/obo/UPHENO_0077863
+http://purl.obolibrary.org/obo/GO_0005634	http://purl.obolibrary.org/obo/UPHENO_0077863
+http://purl.obolibrary.org/obo/GO_0005634	http://purl.obolibrary.org/obo/UPHENO_0077863
+http://purl.obolibrary.org/obo/GO_0005634	http://purl.obolibrary.org/obo/UPHENO_0077863
+http://purl.obolibrary.org/obo/GO_0005634	http://purl.obolibrary.org/obo/UPHENO_0077863
+http://purl.obolibrary.org/obo/GO_0000324	http://purl.obolibrary.org/obo/UPHENO_0085932
+http://purl.obolibrary.org/obo/GO_0005694	http://purl.obolibrary.org/obo/UPHENO_0085690
+http://purl.obolibrary.org/obo/GO_0005694	http://purl.obolibrary.org/obo/UPHENO_0085690
diff --git a/src/curation/upheno-fillers/fypo/abnormalMorphologyOfCellularComponent.tsv b/src/curation/upheno-fillers/fypo/abnormalMorphologyOfCellularComponent.tsv
new file mode 100644
index 00000000..1c401bb3
--- /dev/null
+++ b/src/curation/upheno-fillers/fypo/abnormalMorphologyOfCellularComponent.tsv
@@ -0,0 +1,16 @@
+cellular_component	defined_class
+http://purl.obolibrary.org/obo/GO_0005575	http://purl.obolibrary.org/obo/UPHENO_0067691
+http://purl.obolibrary.org/obo/GO_0005694	http://purl.obolibrary.org/obo/UPHENO_0067694
+http://purl.obolibrary.org/obo/GO_0000776	http://purl.obolibrary.org/obo/UPHENO_0082034
+http://purl.obolibrary.org/obo/GO_0005634	http://purl.obolibrary.org/obo/UPHENO_0067645
+http://purl.obolibrary.org/obo/GO_0000324	http://purl.obolibrary.org/obo/UPHENO_0082035
+http://purl.obolibrary.org/obo/GO_0030998	http://purl.obolibrary.org/obo/UPHENO_0082036
+http://purl.obolibrary.org/obo/GO_0000781	http://purl.obolibrary.org/obo/UPHENO_0067651
+http://purl.obolibrary.org/obo/GO_0005856	http://purl.obolibrary.org/obo/UPHENO_0067705
+http://purl.obolibrary.org/obo/GO_0005619	http://purl.obolibrary.org/obo/UPHENO_0082037
+http://purl.obolibrary.org/obo/GO_0005938	http://purl.obolibrary.org/obo/UPHENO_0082038
+http://purl.obolibrary.org/obo/GO_0005937	http://purl.obolibrary.org/obo/UPHENO_0082039
+http://purl.obolibrary.org/obo/GO_0005816	http://purl.obolibrary.org/obo/UPHENO_0082040
+http://purl.obolibrary.org/obo/GO_0005819	http://purl.obolibrary.org/obo/UPHENO_0082041
+http://purl.obolibrary.org/obo/GO_0015630	http://purl.obolibrary.org/obo/UPHENO_0067659
+http://purl.obolibrary.org/obo/GO_0009277	http://purl.obolibrary.org/obo/UPHENO_0082042
diff --git a/src/curation/upheno-fillers/fypo/abnormalMorphologyOfPartOfAnatomicalEntity-modified.tsv b/src/curation/upheno-fillers/fypo/abnormalMorphologyOfPartOfAnatomicalEntity-modified.tsv
new file mode 100644
index 00000000..89f075cb
--- /dev/null
+++ b/src/curation/upheno-fillers/fypo/abnormalMorphologyOfPartOfAnatomicalEntity-modified.tsv
@@ -0,0 +1,18 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0009277	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0015630	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000596	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000521	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0005819	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0005619	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0005938	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0005937	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0005816	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0030998	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0000781	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0005856	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0000776	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0005634	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0000324	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0005694	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/fypo/abnormalRateOfBiologicalProcess.tsv b/src/curation/upheno-fillers/fypo/abnormalRateOfBiologicalProcess.tsv
new file mode 100644
index 00000000..3ae28281
--- /dev/null
+++ b/src/curation/upheno-fillers/fypo/abnormalRateOfBiologicalProcess.tsv
@@ -0,0 +1,3 @@
+biological_process	defined_class
+http://purl.obolibrary.org/obo/GO_0016049	http://purl.obolibrary.org/obo/UPHENO_0080419
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UPHENO_0080377
diff --git a/src/curation/upheno-fillers/fypo/abnormalShapeOfAnatomicalEntityByShapeType.tsv b/src/curation/upheno-fillers/fypo/abnormalShapeOfAnatomicalEntityByShapeType.tsv
new file mode 100644
index 00000000..110d211f
--- /dev/null
+++ b/src/curation/upheno-fillers/fypo/abnormalShapeOfAnatomicalEntityByShapeType.tsv
@@ -0,0 +1 @@
+entity	shape	defined_class
diff --git a/src/curation/upheno-fillers/fypo/abnormalShapeOfPhysicalEntity.tsv b/src/curation/upheno-fillers/fypo/abnormalShapeOfPhysicalEntity.tsv
new file mode 100644
index 00000000..88098a53
--- /dev/null
+++ b/src/curation/upheno-fillers/fypo/abnormalShapeOfPhysicalEntity.tsv
@@ -0,0 +1,4 @@
+entity	defined_class
+http://purl.obolibrary.org/obo/BFO_0000002	http://purl.obolibrary.org/obo/UPHENO_0080300
+http://purl.obolibrary.org/obo/CL_0000521	http://purl.obolibrary.org/obo/UPHENO_0080301
+http://purl.obolibrary.org/obo/CL_0000596	http://purl.obolibrary.org/obo/UPHENO_0080302
diff --git a/src/curation/upheno-fillers/fypo/abnormalSizeOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/fypo/abnormalSizeOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..cf556244
--- /dev/null
+++ b/src/curation/upheno-fillers/fypo/abnormalSizeOfAnatomicalEntity.tsv
@@ -0,0 +1,3 @@
+entity	defined_class
+http://purl.obolibrary.org/obo/CL_0000521	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0075195
diff --git a/src/curation/upheno-fillers/fypo/abnormallyDecreasedOccurrenceOfBiologicalProcess.tsv b/src/curation/upheno-fillers/fypo/abnormallyDecreasedOccurrenceOfBiologicalProcess.tsv
new file mode 100644
index 00000000..bea0eb03
--- /dev/null
+++ b/src/curation/upheno-fillers/fypo/abnormallyDecreasedOccurrenceOfBiologicalProcess.tsv
@@ -0,0 +1,3 @@
+biological_process	defined_class
+http://purl.obolibrary.org/obo/GO_0010467	http://purl.obolibrary.org/obo/UPHENO_0082858
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UPHENO_0077429
diff --git a/src/curation/upheno-fillers/fypo/abnormallyDecreasedRateOfBiologicalProcess.tsv b/src/curation/upheno-fillers/fypo/abnormallyDecreasedRateOfBiologicalProcess.tsv
new file mode 100644
index 00000000..e927a353
--- /dev/null
+++ b/src/curation/upheno-fillers/fypo/abnormallyDecreasedRateOfBiologicalProcess.tsv
@@ -0,0 +1,3 @@
+biological_process	defined_class
+http://purl.obolibrary.org/obo/GO_0016049	http://purl.obolibrary.org/obo/UPHENO_0076903
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UPHENO_0005433
diff --git a/src/curation/upheno-fillers/fypo/abnormallyIncreasedOccurrenceOfBiologicalProcess.tsv b/src/curation/upheno-fillers/fypo/abnormallyIncreasedOccurrenceOfBiologicalProcess.tsv
new file mode 100644
index 00000000..4e3fc86a
--- /dev/null
+++ b/src/curation/upheno-fillers/fypo/abnormallyIncreasedOccurrenceOfBiologicalProcess.tsv
@@ -0,0 +1,4 @@
+biological_process	defined_class
+http://purl.obolibrary.org/obo/GO_0010467	http://purl.obolibrary.org/obo/UPHENO_0081696
+http://purl.obolibrary.org/obo/GO_1903260	http://purl.obolibrary.org/obo/UPHENO_0081697
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UPHENO_0079251
diff --git a/src/curation/upheno-fillers/hp/abnormalAbsenceOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/hp/abnormalAbsenceOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..fce18e38
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormalAbsenceOfAnatomicalEntity.tsv
@@ -0,0 +1,103 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001350	http://purl.obolibrary.org/obo/UPHENO_0009287
+http://purl.obolibrary.org/obo/UBERON_0005438	http://purl.obolibrary.org/obo/UPHENO_0008511
+http://purl.obolibrary.org/obo/UBERON_0000388	http://purl.obolibrary.org/obo/UPHENO_0008636
+http://purl.obolibrary.org/obo/UBERON_0006767	http://purl.obolibrary.org/obo/UPHENO_0009372
+http://purl.obolibrary.org/obo/UBERON_0002446	http://purl.obolibrary.org/obo/UPHENO_0009098
+http://purl.obolibrary.org/obo/UBERON_0002046	http://purl.obolibrary.org/obo/UPHENO_0009373
+http://purl.obolibrary.org/obo/UBERON_0003407	http://purl.obolibrary.org/obo/UPHENO_0008645
+http://purl.obolibrary.org/obo/UBERON_0013698	http://purl.obolibrary.org/obo/UPHENO_0009292
+http://purl.obolibrary.org/obo/UBERON_0013699	http://purl.obolibrary.org/obo/UPHENO_0009293
+http://purl.obolibrary.org/obo/UBERON_0011273	http://purl.obolibrary.org/obo/UPHENO_0009294
+http://purl.obolibrary.org/obo/UBERON_0011278	http://purl.obolibrary.org/obo/UPHENO_0009296
+http://purl.obolibrary.org/obo/UBERON_0011277	http://purl.obolibrary.org/obo/UPHENO_0009297
+http://purl.obolibrary.org/obo/UBERON_0001908	http://purl.obolibrary.org/obo/UPHENO_0008422
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0008523
+http://purl.obolibrary.org/obo/UBERON_0004176	http://purl.obolibrary.org/obo/UPHENO_0008423
+http://purl.obolibrary.org/obo/UBERON_0002030	http://purl.obolibrary.org/obo/UPHENO_0008964
+http://purl.obolibrary.org/obo/UBERON_0004175	http://purl.obolibrary.org/obo/UPHENO_0008425
+http://purl.obolibrary.org/obo/UBERON_0001466	http://purl.obolibrary.org/obo/UPHENO_0008652
+http://purl.obolibrary.org/obo/UBERON_0001103	http://purl.obolibrary.org/obo/UPHENO_0009298
+http://purl.obolibrary.org/obo/UBERON_0001100	http://purl.obolibrary.org/obo/UPHENO_0009299
+http://purl.obolibrary.org/obo/UBERON_0001463	http://purl.obolibrary.org/obo/UPHENO_0009300
+http://purl.obolibrary.org/obo/UBERON_0010171	http://purl.obolibrary.org/obo/UPHENO_0009301
+http://purl.obolibrary.org/obo/UBERON_0001734	http://purl.obolibrary.org/obo/UPHENO_0009379
+http://purl.obolibrary.org/obo/UBERON_0001691	http://purl.obolibrary.org/obo/UPHENO_0009305
+http://purl.obolibrary.org/obo/UBERON_0000002	http://purl.obolibrary.org/obo/UPHENO_0009306
+http://purl.obolibrary.org/obo/UBERON_0002389	http://purl.obolibrary.org/obo/UPHENO_0009382
+http://purl.obolibrary.org/obo/UBERON_0002386	http://purl.obolibrary.org/obo/UPHENO_0009384
+http://purl.obolibrary.org/obo/UBERON_0004720	http://purl.obolibrary.org/obo/UPHENO_0009308
+http://purl.obolibrary.org/obo/UBERON_0002146	http://purl.obolibrary.org/obo/UPHENO_0009385
+http://purl.obolibrary.org/obo/UBERON_0019255	http://purl.obolibrary.org/obo/UPHENO_0009387
+http://purl.obolibrary.org/obo/UBERON_0005928	http://purl.obolibrary.org/obo/UPHENO_0009309
+http://purl.obolibrary.org/obo/UBERON_0000996	http://purl.obolibrary.org/obo/UPHENO_0008771
+http://purl.obolibrary.org/obo/UBERON_0001844	http://purl.obolibrary.org/obo/UPHENO_0009388
+http://purl.obolibrary.org/obo/UBERON_0001601	http://purl.obolibrary.org/obo/UPHENO_0008773
+http://purl.obolibrary.org/obo/UBERON_0001689	http://purl.obolibrary.org/obo/UPHENO_0009311
+http://purl.obolibrary.org/obo/UBERON_0019254	http://purl.obolibrary.org/obo/UPHENO_0009389
+http://purl.obolibrary.org/obo/UBERON_0004714	http://purl.obolibrary.org/obo/UPHENO_0009312
+http://purl.obolibrary.org/obo/UBERON_0001846	http://purl.obolibrary.org/obo/UPHENO_0008775
+http://purl.obolibrary.org/obo/UBERON_0010163	http://purl.obolibrary.org/obo/UPHENO_0009315
+http://purl.obolibrary.org/obo/UBERON_0002372	http://purl.obolibrary.org/obo/UPHENO_0009392
+http://purl.obolibrary.org/obo/UBERON_0004390	http://purl.obolibrary.org/obo/UPHENO_0009316
+http://purl.obolibrary.org/obo/UBERON_0003865	http://purl.obolibrary.org/obo/UPHENO_0009318
+http://purl.obolibrary.org/obo/UBERON_0002412	http://purl.obolibrary.org/obo/UPHENO_0009145
+http://purl.obolibrary.org/obo/UBERON_0001840	http://purl.obolibrary.org/obo/UPHENO_0008778
+http://purl.obolibrary.org/obo/UBERON_0001446	http://purl.obolibrary.org/obo/UPHENO_0008691
+http://purl.obolibrary.org/obo/UBERON_0001445	http://purl.obolibrary.org/obo/UPHENO_0009321
+http://purl.obolibrary.org/obo/UBERON_0001687	http://purl.obolibrary.org/obo/UPHENO_0009322
+http://purl.obolibrary.org/obo/UBERON_0000995	http://purl.obolibrary.org/obo/UPHENO_0009396
+http://purl.obolibrary.org/obo/UBERON_0002017	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002012	http://purl.obolibrary.org/obo/UPHENO_0009006
+http://purl.obolibrary.org/obo/UBERON_0009565	http://purl.obolibrary.org/obo/UPHENO_0009398
+http://purl.obolibrary.org/obo/UBERON_0003466	http://purl.obolibrary.org/obo/UPHENO_0009399
+http://purl.obolibrary.org/obo/UBERON_0002374	http://purl.obolibrary.org/obo/UPHENO_0009400
+http://purl.obolibrary.org/obo/UBERON_0001442	http://purl.obolibrary.org/obo/UPHENO_0009324
+http://purl.obolibrary.org/obo/UBERON_0009567	http://purl.obolibrary.org/obo/UPHENO_0009403
+http://purl.obolibrary.org/obo/UBERON_0001437	http://purl.obolibrary.org/obo/UPHENO_0009327
+http://purl.obolibrary.org/obo/UBERON_0002407	http://purl.obolibrary.org/obo/UPHENO_0009329
+http://purl.obolibrary.org/obo/UBERON_0003690	http://purl.obolibrary.org/obo/UPHENO_0009404
+http://purl.obolibrary.org/obo/UBERON_0001037	http://purl.obolibrary.org/obo/UPHENO_0008567
+http://purl.obolibrary.org/obo/UBERON_0000981	http://purl.obolibrary.org/obo/UPHENO_0008790
+http://purl.obolibrary.org/obo/UBERON_0008340	http://purl.obolibrary.org/obo/UPHENO_0009406
+http://purl.obolibrary.org/obo/UBERON_0000102	http://purl.obolibrary.org/obo/UPHENO_0009333
+http://purl.obolibrary.org/obo/UBERON_0002369	http://purl.obolibrary.org/obo/UPHENO_0009407
+http://purl.obolibrary.org/obo/UBERON_0005236	http://purl.obolibrary.org/obo/UPHENO_0008471
+http://purl.obolibrary.org/obo/UBERON_0002000	http://purl.obolibrary.org/obo/UPHENO_0009408
+http://purl.obolibrary.org/obo/UBERON_0009039	http://purl.obolibrary.org/obo/UPHENO_0009170
+http://purl.obolibrary.org/obo/UBERON_0001825	http://purl.obolibrary.org/obo/UPHENO_0008795
+http://purl.obolibrary.org/obo/UBERON_0000979	http://purl.obolibrary.org/obo/UPHENO_0009410
+http://purl.obolibrary.org/obo/UBERON_0001821	http://purl.obolibrary.org/obo/UPHENO_0008797
+http://purl.obolibrary.org/obo/UBERON_0000975	http://purl.obolibrary.org/obo/UPHENO_0009412
+http://purl.obolibrary.org/obo/UBERON_0001702	http://purl.obolibrary.org/obo/UPHENO_0009414
+http://purl.obolibrary.org/obo/UBERON_0001427	http://purl.obolibrary.org/obo/UPHENO_0009338
+http://purl.obolibrary.org/obo/UBERON_0010887	http://purl.obolibrary.org/obo/UPHENO_0009415
+http://purl.obolibrary.org/obo/UBERON_0002190	http://purl.obolibrary.org/obo/UPHENO_0008479
+http://purl.obolibrary.org/obo/UBERON_0011859	http://purl.obolibrary.org/obo/UPHENO_0009417
+http://purl.obolibrary.org/obo/UBERON_0003723	http://purl.obolibrary.org/obo/UPHENO_0009339
+http://purl.obolibrary.org/obo/UBERON_0004413	http://purl.obolibrary.org/obo/UPHENO_0009418
+http://purl.obolibrary.org/obo/UBERON_0001424	http://purl.obolibrary.org/obo/UPHENO_0009340
+http://purl.obolibrary.org/obo/UBERON_0001423	http://purl.obolibrary.org/obo/UPHENO_0009341
+http://purl.obolibrary.org/obo/UBERON_0002352	http://purl.obolibrary.org/obo/UPHENO_0008590
+http://purl.obolibrary.org/obo/UBERON_0002110	http://purl.obolibrary.org/obo/UPHENO_0009420
+http://purl.obolibrary.org/obo/UBERON_0002198	http://purl.obolibrary.org/obo/UPHENO_0009342
+http://purl.obolibrary.org/obo/UBERON_0002113	http://purl.obolibrary.org/obo/UPHENO_0008593
+http://purl.obolibrary.org/obo/UBERON_0001782	http://purl.obolibrary.org/obo/UPHENO_0009343
+http://purl.obolibrary.org/obo/UBERON_0011220	http://purl.obolibrary.org/obo/UPHENO_0009346
+http://purl.obolibrary.org/obo/UBERON_0001091	http://purl.obolibrary.org/obo/UPHENO_0009348
+http://purl.obolibrary.org/obo/UBERON_0002106	http://purl.obolibrary.org/obo/UPHENO_0008606
+http://purl.obolibrary.org/obo/UBERON_0007119	http://purl.obolibrary.org/obo/UPHENO_0009426
+http://purl.obolibrary.org/obo/UBERON_0001891	http://purl.obolibrary.org/obo/UPHENO_0008732
+http://purl.obolibrary.org/obo/UBERON_0002343	http://purl.obolibrary.org/obo/UPHENO_0009429
+http://purl.obolibrary.org/obo/UBERON_0001769	http://purl.obolibrary.org/obo/UPHENO_0009208
+http://purl.obolibrary.org/obo/CL_0000623	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000625	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0016466	http://purl.obolibrary.org/obo/UPHENO_0009359
+http://purl.obolibrary.org/obo/UBERON_0011575	http://purl.obolibrary.org/obo/UPHENO_0009361
+http://purl.obolibrary.org/obo/UBERON_0016467	http://purl.obolibrary.org/obo/UPHENO_0009362
+http://purl.obolibrary.org/obo/CL_0000236	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0006657	http://purl.obolibrary.org/obo/UPHENO_0009365
+http://purl.obolibrary.org/obo/UBERON_0002336	http://purl.obolibrary.org/obo/UPHENO_0008622
+http://purl.obolibrary.org/obo/UBERON_0002453	http://purl.obolibrary.org/obo/UPHENO_0009431
+http://purl.obolibrary.org/obo/UBERON_0011282	http://purl.obolibrary.org/obo/UPHENO_0009432
+http://purl.obolibrary.org/obo/UBERON_0010230	http://purl.obolibrary.org/obo/UPHENO_0009368
diff --git a/src/curation/upheno-fillers/hp/abnormalAbsenceOfAnatomicalEntityInLocation.tsv b/src/curation/upheno-fillers/hp/abnormalAbsenceOfAnatomicalEntityInLocation.tsv
new file mode 100644
index 00000000..086c23b0
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormalAbsenceOfAnatomicalEntityInLocation.tsv
@@ -0,0 +1,105 @@
+anatomical_entity	location	defined_class
+http://purl.obolibrary.org/obo/UBERON_0002221	http://purl.obolibrary.org/obo/UBERON_0004339	http://purl.obolibrary.org/obo/UPHENO_0027507
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0003650	http://purl.obolibrary.org/obo/UPHENO_0027508
+http://purl.obolibrary.org/obo/UBERON_0001076	http://purl.obolibrary.org/obo/UBERON_0009568	http://purl.obolibrary.org/obo/UPHENO_0027408
+http://purl.obolibrary.org/obo/UBERON_0000991	http://purl.obolibrary.org/obo/UBERON_0000479	http://purl.obolibrary.org/obo/UPHENO_0027272
+http://purl.obolibrary.org/obo/UBERON_0001437	http://purl.obolibrary.org/obo/UBERON_0004318	http://purl.obolibrary.org/obo/UPHENO_0027278
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0004336	http://purl.obolibrary.org/obo/UPHENO_0027078
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diff --git a/src/curation/upheno-fillers/hp/abnormalAbsenceOfBehavior.tsv b/src/curation/upheno-fillers/hp/abnormalAbsenceOfBehavior.tsv
new file mode 100644
index 00000000..c5eb1943
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormalAbsenceOfBehavior.tsv
@@ -0,0 +1,5 @@
+behavior_process	defined_class
+http://purl.obolibrary.org/obo/NBO_0000313	http://purl.obolibrary.org/obo/UPHENO_0063688
+http://purl.obolibrary.org/obo/NBO_0000313	http://purl.obolibrary.org/obo/UPHENO_0063688
+http://purl.obolibrary.org/obo/NBO_0000043	http://purl.obolibrary.org/obo/UPHENO_0063697
+http://purl.obolibrary.org/obo/NBO_0000011	http://purl.obolibrary.org/obo/UPHENO_0063698
diff --git a/src/curation/upheno-fillers/hp/abnormalAbsenceOfBiologicalProcess.tsv b/src/curation/upheno-fillers/hp/abnormalAbsenceOfBiologicalProcess.tsv
new file mode 100644
index 00000000..93532905
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormalAbsenceOfBiologicalProcess.tsv
@@ -0,0 +1,12 @@
+biological_process	defined_class
+http://purl.obolibrary.org/obo/GO_0007601	http://purl.obolibrary.org/obo/UPHENO_0078456
+http://purl.obolibrary.org/obo/GO_0022011	http://purl.obolibrary.org/obo/UPHENO_0078486
+http://purl.obolibrary.org/obo/GO_0042703	http://purl.obolibrary.org/obo/UPHENO_0078479
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UPHENO_0034024
+http://purl.obolibrary.org/obo/GO_0050881	http://purl.obolibrary.org/obo/UPHENO_0078487
+http://purl.obolibrary.org/obo/NBO_0000043	http://purl.obolibrary.org/obo/UPHENO_0080956
+http://purl.obolibrary.org/obo/GO_0046543	http://purl.obolibrary.org/obo/UPHENO_0078488
+http://purl.obolibrary.org/obo/GO_0060073	http://purl.obolibrary.org/obo/UPHENO_0078474
+http://purl.obolibrary.org/obo/GO_0007585	http://purl.obolibrary.org/obo/UPHENO_0078461
+http://purl.obolibrary.org/obo/NBO_0000011	http://purl.obolibrary.org/obo/UPHENO_0080957
+http://purl.obolibrary.org/obo/GO_0045136	http://purl.obolibrary.org/obo/UPHENO_0078489
diff --git a/src/curation/upheno-fillers/hp/abnormalAbsenceOfBiologicalProcessInLocation.tsv b/src/curation/upheno-fillers/hp/abnormalAbsenceOfBiologicalProcessInLocation.tsv
new file mode 100644
index 00000000..d08d1747
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormalAbsenceOfBiologicalProcessInLocation.tsv
@@ -0,0 +1,29 @@
+biological_process	location	defined_class
+http://purl.obolibrary.org/obo/GO_0001503	http://purl.obolibrary.org/obo/UBERON_0003690	http://purl.obolibrary.org/obo/UPHENO_0071154
+http://purl.obolibrary.org/obo/GO_0001503	http://purl.obolibrary.org/obo/UBERON_0001075	http://purl.obolibrary.org/obo/UPHENO_0071155
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0010230	http://purl.obolibrary.org/obo/UPHENO_0071132
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0001868	http://purl.obolibrary.org/obo/UPHENO_0071159
+http://purl.obolibrary.org/obo/GO_0001503	http://purl.obolibrary.org/obo/UBERON_0004382	http://purl.obolibrary.org/obo/UPHENO_0071160
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0000975	http://purl.obolibrary.org/obo/UPHENO_0071161
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0002097	http://purl.obolibrary.org/obo/UPHENO_0071024
+http://purl.obolibrary.org/obo/GO_0043473	http://purl.obolibrary.org/obo/UBERON_0001416	http://purl.obolibrary.org/obo/UPHENO_0071135
+http://purl.obolibrary.org/obo/GO_0060004	http://purl.obolibrary.org/obo/UBERON_0010708	http://purl.obolibrary.org/obo/UPHENO_0071136
+http://purl.obolibrary.org/obo/GO_0060004	http://purl.obolibrary.org/obo/UBERON_0010709	http://purl.obolibrary.org/obo/UPHENO_0071137
+http://purl.obolibrary.org/obo/GO_0001503	http://purl.obolibrary.org/obo/UBERON_0000975	http://purl.obolibrary.org/obo/UPHENO_0071164
+http://purl.obolibrary.org/obo/GO_0043473	http://purl.obolibrary.org/obo/UBERON_0001419	http://purl.obolibrary.org/obo/UPHENO_0071138
+http://purl.obolibrary.org/obo/GO_0043473	http://purl.obolibrary.org/obo/UBERON_0019200	http://purl.obolibrary.org/obo/UPHENO_0071139
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0019200	http://purl.obolibrary.org/obo/UPHENO_0071140
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0001419	http://purl.obolibrary.org/obo/UPHENO_0071165
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0001682	http://purl.obolibrary.org/obo/UPHENO_0071143
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0001416	http://purl.obolibrary.org/obo/UPHENO_0071167
+http://purl.obolibrary.org/obo/GO_0043473	http://purl.obolibrary.org/obo/UBERON_0002097	http://purl.obolibrary.org/obo/UPHENO_0071117
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0003690	http://purl.obolibrary.org/obo/UPHENO_0071145
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0001075	http://purl.obolibrary.org/obo/UPHENO_0071146
+http://purl.obolibrary.org/obo/GO_0043473	http://purl.obolibrary.org/obo/UBERON_0001868	http://purl.obolibrary.org/obo/UPHENO_0071147
+http://purl.obolibrary.org/obo/GO_0001503	http://purl.obolibrary.org/obo/UBERON_0001682	http://purl.obolibrary.org/obo/UPHENO_0071148
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0003951	http://purl.obolibrary.org/obo/UPHENO_0071173
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0010708	http://purl.obolibrary.org/obo/UPHENO_0071149
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0010709	http://purl.obolibrary.org/obo/UPHENO_0071150
+http://purl.obolibrary.org/obo/GO_0006582	http://purl.obolibrary.org/obo/UBERON_0010230	http://purl.obolibrary.org/obo/UPHENO_0071175
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0004382	http://purl.obolibrary.org/obo/UPHENO_0071151
+http://purl.obolibrary.org/obo/GO_0043473	http://purl.obolibrary.org/obo/UBERON_0003951	http://purl.obolibrary.org/obo/UPHENO_0071178
diff --git a/src/curation/upheno-fillers/hp/abnormalAbsenceOfChemicalEntity.tsv b/src/curation/upheno-fillers/hp/abnormalAbsenceOfChemicalEntity.tsv
new file mode 100644
index 00000000..5f7b6386
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormalAbsenceOfChemicalEntity.tsv
@@ -0,0 +1,4 @@
+chemical_entity	defined_class
+http://purl.obolibrary.org/obo/PR_000007975	http://purl.obolibrary.org/obo/UPHENO_0048689
+http://purl.obolibrary.org/obo/CHEBI_60525	http://purl.obolibrary.org/obo/UPHENO_0048690
+http://purl.obolibrary.org/obo/CHEBI_24431	http://purl.obolibrary.org/obo/UPHENO_0048687
diff --git a/src/curation/upheno-fillers/hp/abnormalAbsenceOfChemicalEntityInLocation.tsv b/src/curation/upheno-fillers/hp/abnormalAbsenceOfChemicalEntityInLocation.tsv
new file mode 100644
index 00000000..7cd59fe9
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormalAbsenceOfChemicalEntityInLocation.tsv
@@ -0,0 +1,3 @@
+chemical_entity	location	defined_class
+http://purl.obolibrary.org/obo/CHEBI_24431	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0049570
+http://purl.obolibrary.org/obo/CHEBI_39026	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0049574
diff --git a/src/curation/upheno-fillers/hp/abnormalAgenesisOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/hp/abnormalAgenesisOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..36d8361f
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormalAgenesisOfAnatomicalEntity.tsv
@@ -0,0 +1,31 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0003450	http://purl.obolibrary.org/obo/UPHENO_0080314
+http://purl.obolibrary.org/obo/UBERON_0003451	http://purl.obolibrary.org/obo/UPHENO_0080315
+http://purl.obolibrary.org/obo/UBERON_0003655	http://purl.obolibrary.org/obo/UPHENO_0080316
+http://purl.obolibrary.org/obo/UBERON_0001874	http://purl.obolibrary.org/obo/UPHENO_0080317
+http://purl.obolibrary.org/obo/UBERON_0003674	http://purl.obolibrary.org/obo/UPHENO_0080318
+http://purl.obolibrary.org/obo/UBERON_0001098	http://purl.obolibrary.org/obo/UPHENO_0080319
+http://purl.obolibrary.org/obo/UBERON_0018603	http://purl.obolibrary.org/obo/UPHENO_0080320
+http://purl.obolibrary.org/obo/UBERON_0018604	http://purl.obolibrary.org/obo/UPHENO_0080321
+http://purl.obolibrary.org/obo/UBERON_0018601	http://purl.obolibrary.org/obo/UPHENO_0080322
+http://purl.obolibrary.org/obo/UBERON_0018568	http://purl.obolibrary.org/obo/UPHENO_0080323
+http://purl.obolibrary.org/obo/UBERON_0018602	http://purl.obolibrary.org/obo/UPHENO_0080324
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0080325
+http://purl.obolibrary.org/obo/UBERON_0013618	http://purl.obolibrary.org/obo/UPHENO_0080326
+http://purl.obolibrary.org/obo/UBERON_0007120	http://purl.obolibrary.org/obo/UPHENO_0080327
+http://purl.obolibrary.org/obo/UBERON_0018607	http://purl.obolibrary.org/obo/UPHENO_0080328
+http://purl.obolibrary.org/obo/UBERON_0018608	http://purl.obolibrary.org/obo/UPHENO_0080329
+http://purl.obolibrary.org/obo/UBERON_0002413	http://purl.obolibrary.org/obo/UPHENO_0080330
+http://purl.obolibrary.org/obo/UBERON_0005366	http://purl.obolibrary.org/obo/UPHENO_0080331
+http://purl.obolibrary.org/obo/UBERON_0018551	http://purl.obolibrary.org/obo/UPHENO_0080332
+http://purl.obolibrary.org/obo/UBERON_0016453	http://purl.obolibrary.org/obo/UPHENO_0080333
+http://purl.obolibrary.org/obo/UBERON_0018595	http://purl.obolibrary.org/obo/UPHENO_0080334
+http://purl.obolibrary.org/obo/UBERON_0018552	http://purl.obolibrary.org/obo/UPHENO_0080335
+http://purl.obolibrary.org/obo/UBERON_0016452	http://purl.obolibrary.org/obo/UPHENO_0080336
+http://purl.obolibrary.org/obo/UBERON_0018596	http://purl.obolibrary.org/obo/UPHENO_0080337
+http://purl.obolibrary.org/obo/UBERON_0018593	http://purl.obolibrary.org/obo/UPHENO_0080338
+http://purl.obolibrary.org/obo/UBERON_0018594	http://purl.obolibrary.org/obo/UPHENO_0080339
+http://purl.obolibrary.org/obo/UBERON_0002107	http://purl.obolibrary.org/obo/UPHENO_0080340
+http://purl.obolibrary.org/obo/UBERON_0018570	http://purl.obolibrary.org/obo/UPHENO_0080341
+http://purl.obolibrary.org/obo/UBERON_0016455	http://purl.obolibrary.org/obo/UPHENO_0080342
+http://purl.obolibrary.org/obo/UBERON_0016454	http://purl.obolibrary.org/obo/UPHENO_0080343
diff --git a/src/curation/upheno-fillers/hp/abnormalAnatomicalEntity-modified.tsv b/src/curation/upheno-fillers/hp/abnormalAnatomicalEntity-modified.tsv
new file mode 100644
index 00000000..e8a0f549
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormalAnatomicalEntity-modified.tsv
@@ -0,0 +1,3 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0004535	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/hp/abnormalAnatomicalEntity.tsv b/src/curation/upheno-fillers/hp/abnormalAnatomicalEntity.tsv
new file mode 100644
index 00000000..524e55f7
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormalAnatomicalEntity.tsv
@@ -0,0 +1,356 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0035639	http://purl.obolibrary.org/obo/UPHENO_0075878
+http://purl.obolibrary.org/obo/UBERON_0001598	http://purl.obolibrary.org/obo/UPHENO_0075879
+http://purl.obolibrary.org/obo/UBERON_0002324	http://purl.obolibrary.org/obo/UPHENO_0002857
+http://purl.obolibrary.org/obo/UBERON_0002203	http://purl.obolibrary.org/obo/UPHENO_0005090
+http://purl.obolibrary.org/obo/UBERON_0001235	http://purl.obolibrary.org/obo/UPHENO_0003428
+http://purl.obolibrary.org/obo/UBERON_0001597	http://purl.obolibrary.org/obo/UPHENO_0075880
+http://purl.obolibrary.org/obo/UBERON_0004864	http://purl.obolibrary.org/obo/UPHENO_0005091
+http://purl.obolibrary.org/obo/UBERON_0003654	http://purl.obolibrary.org/obo/UPHENO_0075881
+http://purl.obolibrary.org/obo/UBERON_0003897	http://purl.obolibrary.org/obo/UPHENO_0002863
+http://purl.obolibrary.org/obo/UBERON_0003655	http://purl.obolibrary.org/obo/UPHENO_0075882
+http://purl.obolibrary.org/obo/UBERON_0001352	http://purl.obolibrary.org/obo/UPHENO_0002865
+http://purl.obolibrary.org/obo/UBERON_0003652	http://purl.obolibrary.org/obo/UPHENO_0075883
+http://purl.obolibrary.org/obo/UBERON_0003653	http://purl.obolibrary.org/obo/UPHENO_0075884
+http://purl.obolibrary.org/obo/UBERON_0003650	http://purl.obolibrary.org/obo/UPHENO_0075885
+http://purl.obolibrary.org/obo/UBERON_0003651	http://purl.obolibrary.org/obo/UPHENO_0075886
+http://purl.obolibrary.org/obo/UBERON_0000935	http://purl.obolibrary.org/obo/UPHENO_0002589
+http://purl.obolibrary.org/obo/UBERON_0001905	http://purl.obolibrary.org/obo/UPHENO_0002591
+http://purl.obolibrary.org/obo/UBERON_0013698	http://purl.obolibrary.org/obo/UPHENO_0075888
+http://purl.obolibrary.org/obo/UBERON_0018229	http://purl.obolibrary.org/obo/UPHENO_0002592
+http://purl.obolibrary.org/obo/UBERON_0013699	http://purl.obolibrary.org/obo/UPHENO_0075889
+http://purl.obolibrary.org/obo/UBERON_0018226	http://purl.obolibrary.org/obo/UPHENO_0075755
+http://purl.obolibrary.org/obo/UBERON_0004176	http://purl.obolibrary.org/obo/UPHENO_0002595
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+http://purl.obolibrary.org/obo/UBERON_0011931	http://purl.obolibrary.org/obo/UPHENO_0075756
+http://purl.obolibrary.org/obo/UBERON_0001581	http://purl.obolibrary.org/obo/UPHENO_0075891
+http://purl.obolibrary.org/obo/UBERON_0001460	http://purl.obolibrary.org/obo/UPHENO_0002880
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+http://purl.obolibrary.org/obo/UBERON_0001580	http://purl.obolibrary.org/obo/UPHENO_0075892
+http://purl.obolibrary.org/obo/UBERON_0001224	http://purl.obolibrary.org/obo/UPHENO_0075893
+http://purl.obolibrary.org/obo/UBERON_0001103	http://purl.obolibrary.org/obo/UPHENO_0002882
+http://purl.obolibrary.org/obo/UBERON_0001586	http://purl.obolibrary.org/obo/UPHENO_0004048
+http://purl.obolibrary.org/obo/UBERON_0001465	http://purl.obolibrary.org/obo/UPHENO_0002885
+http://purl.obolibrary.org/obo/UBERON_0000378	http://purl.obolibrary.org/obo/UPHENO_0075894
+http://purl.obolibrary.org/obo/UBERON_0008772	http://purl.obolibrary.org/obo/UPHENO_0075757
+http://purl.obolibrary.org/obo/UBERON_0001582	http://purl.obolibrary.org/obo/UPHENO_0075896
+http://purl.obolibrary.org/obo/UBERON_0001461	http://purl.obolibrary.org/obo/UPHENO_0002890
+http://purl.obolibrary.org/obo/UBERON_0000010	http://purl.obolibrary.org/obo/UPHENO_0005116
+http://purl.obolibrary.org/obo/UBERON_0003642	http://purl.obolibrary.org/obo/UPHENO_0075897
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+http://purl.obolibrary.org/obo/UBERON_0000012	http://purl.obolibrary.org/obo/UPHENO_0075899
+http://purl.obolibrary.org/obo/UBERON_0014891	http://purl.obolibrary.org/obo/UPHENO_0002892
+http://purl.obolibrary.org/obo/UBERON_0004727	http://purl.obolibrary.org/obo/UPHENO_0075900
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+http://purl.obolibrary.org/obo/UBERON_0002428	http://purl.obolibrary.org/obo/UPHENO_0002896
+http://purl.obolibrary.org/obo/UBERON_0034681	http://purl.obolibrary.org/obo/UPHENO_0075901
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+http://purl.obolibrary.org/obo/UBERON_0010953	http://purl.obolibrary.org/obo/UPHENO_0075759
+http://purl.obolibrary.org/obo/UBERON_0001691	http://purl.obolibrary.org/obo/UPHENO_0002901
+http://purl.obolibrary.org/obo/UBERON_0010952	http://purl.obolibrary.org/obo/UPHENO_0075760
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+http://purl.obolibrary.org/obo/UBERON_0004714	http://purl.obolibrary.org/obo/UPHENO_0002921
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+http://purl.obolibrary.org/obo/UBERON_0004395	http://purl.obolibrary.org/obo/UPHENO_0075762
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+http://purl.obolibrary.org/obo/GO_0005739	http://purl.obolibrary.org/obo/UPHENO_0084757
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+http://purl.obolibrary.org/obo/UBERON_0017717	http://purl.obolibrary.org/obo/UPHENO_0002787
+http://purl.obolibrary.org/obo/UBERON_0000057	http://purl.obolibrary.org/obo/UPHENO_0002790
+http://purl.obolibrary.org/obo/UBERON_0001028	http://purl.obolibrary.org/obo/UPHENO_0075853
+http://purl.obolibrary.org/obo/UBERON_0004413	http://purl.obolibrary.org/obo/UPHENO_0075854
+http://purl.obolibrary.org/obo/UBERON_0003685	http://purl.obolibrary.org/obo/UPHENO_0002798
+http://purl.obolibrary.org/obo/UBERON_0001264	http://purl.obolibrary.org/obo/UPHENO_0002799
+http://purl.obolibrary.org/obo/UBERON_0004411	http://purl.obolibrary.org/obo/UPHENO_0075856
+http://purl.obolibrary.org/obo/UBERON_0001021	http://purl.obolibrary.org/obo/UPHENO_0004508
+http://purl.obolibrary.org/obo/UBERON_0002110	http://purl.obolibrary.org/obo/UPHENO_0002801
+http://purl.obolibrary.org/obo/UBERON_0002113	http://purl.obolibrary.org/obo/UPHENO_0002803
+http://purl.obolibrary.org/obo/UBERON_0004410	http://purl.obolibrary.org/obo/UPHENO_0075857
+http://purl.obolibrary.org/obo/UBERON_0000056	http://purl.obolibrary.org/obo/UPHENO_0002806
+http://purl.obolibrary.org/obo/UBERON_0001815	http://purl.obolibrary.org/obo/UPHENO_0075992
+http://purl.obolibrary.org/obo/UBERON_0001814	http://purl.obolibrary.org/obo/UPHENO_0075993
+http://purl.obolibrary.org/obo/UBERON_0002108	http://purl.obolibrary.org/obo/UPHENO_0002808
+http://purl.obolibrary.org/obo/UBERON_0002107	http://purl.obolibrary.org/obo/UPHENO_0003405
+http://purl.obolibrary.org/obo/UBERON_0001813	http://purl.obolibrary.org/obo/UPHENO_0075994
+http://purl.obolibrary.org/obo/UBERON_0004406	http://purl.obolibrary.org/obo/UPHENO_0075861
+http://purl.obolibrary.org/obo/UBERON_0004407	http://purl.obolibrary.org/obo/UPHENO_0075862
+http://purl.obolibrary.org/obo/UBERON_0001812	http://purl.obolibrary.org/obo/UPHENO_0003083
+http://purl.obolibrary.org/obo/UBERON_0004092	http://purl.obolibrary.org/obo/UPHENO_0075995
+http://purl.obolibrary.org/obo/UBERON_0004090	http://purl.obolibrary.org/obo/UPHENO_0075996
+http://purl.obolibrary.org/obo/UBERON_0001819	http://purl.obolibrary.org/obo/UPHENO_0003085
+http://purl.obolibrary.org/obo/UBERON_0004088	http://purl.obolibrary.org/obo/UPHENO_0075997
+http://purl.obolibrary.org/obo/UBERON_0005056	http://purl.obolibrary.org/obo/UPHENO_0003089
+http://purl.obolibrary.org/obo/UBERON_0001130	http://purl.obolibrary.org/obo/UPHENO_0002813
+http://purl.obolibrary.org/obo/UBERON_0004404	http://purl.obolibrary.org/obo/UPHENO_0075864
+http://purl.obolibrary.org/obo/UBERON_0001015	http://purl.obolibrary.org/obo/UPHENO_0002816
+http://purl.obolibrary.org/obo/UBERON_0004405	http://purl.obolibrary.org/obo/UPHENO_0075865
+http://purl.obolibrary.org/obo/UBERON_0002224	http://purl.obolibrary.org/obo/UPHENO_0075866
+http://purl.obolibrary.org/obo/UBERON_0002106	http://purl.obolibrary.org/obo/UPHENO_0002819
+http://purl.obolibrary.org/obo/UBERON_0003677	http://purl.obolibrary.org/obo/UPHENO_0075867
+http://purl.obolibrary.org/obo/UBERON_0001016	http://purl.obolibrary.org/obo/UPHENO_0004523
+http://purl.obolibrary.org/obo/UBERON_0003674	http://purl.obolibrary.org/obo/UPHENO_0075869
+http://purl.obolibrary.org/obo/UBERON_0002221	http://purl.obolibrary.org/obo/UPHENO_0002821
+http://purl.obolibrary.org/obo/UBERON_0008200	http://purl.obolibrary.org/obo/UPHENO_0003098
+http://purl.obolibrary.org/obo/UBERON_0001132	http://purl.obolibrary.org/obo/UPHENO_0002822
+http://purl.obolibrary.org/obo/UBERON_0000163	http://purl.obolibrary.org/obo/UPHENO_0002824
+http://purl.obolibrary.org/obo/UBERON_0007116	http://purl.obolibrary.org/obo/UPHENO_0003099
+http://purl.obolibrary.org/obo/UBERON_0001255	http://purl.obolibrary.org/obo/UPHENO_0002827
+http://purl.obolibrary.org/obo/UBERON_0003672	http://purl.obolibrary.org/obo/UPHENO_0002826
+http://purl.obolibrary.org/obo/UBERON_0000165	http://purl.obolibrary.org/obo/UPHENO_0002828
+http://purl.obolibrary.org/obo/UBERON_0002343	http://purl.obolibrary.org/obo/UPHENO_0075870
+http://purl.obolibrary.org/obo/UBERON_0002101	http://purl.obolibrary.org/obo/UPHENO_0002830
+http://purl.obolibrary.org/obo/UBERON_0001012	http://purl.obolibrary.org/obo/UPHENO_0002831
+http://purl.obolibrary.org/obo/UBERON_0001008	http://purl.obolibrary.org/obo/UPHENO_0002832
+http://purl.obolibrary.org/obo/UBERON_0001007	http://purl.obolibrary.org/obo/UPHENO_0002833
+http://purl.obolibrary.org/obo/UBERON_0001004	http://purl.obolibrary.org/obo/UPHENO_0004536
+http://purl.obolibrary.org/obo/UBERON_0001245	http://purl.obolibrary.org/obo/UPHENO_0002839
+http://purl.obolibrary.org/obo/UBERON_0002331	http://purl.obolibrary.org/obo/UPHENO_0075872
+http://purl.obolibrary.org/obo/UBERON_0001365	http://purl.obolibrary.org/obo/UPHENO_0075874
+http://purl.obolibrary.org/obo/UBERON_0000033	http://purl.obolibrary.org/obo/UPHENO_0002844
+http://purl.obolibrary.org/obo/UBERON_0002453	http://purl.obolibrary.org/obo/UPHENO_0075875
+http://purl.obolibrary.org/obo/UBERON_0002207	http://purl.obolibrary.org/obo/UPHENO_0075876
+http://purl.obolibrary.org/obo/UBERON_0000949	http://purl.obolibrary.org/obo/UPHENO_0003116
diff --git a/src/curation/upheno-fillers/hp/abnormalAnatomicalEntityNotParts.tsv b/src/curation/upheno-fillers/hp/abnormalAnatomicalEntityNotParts.tsv
new file mode 100644
index 00000000..cd46ee7b
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormalAnatomicalEntityNotParts.tsv
@@ -0,0 +1,4 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0075696
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0075696
+http://purl.obolibrary.org/obo/UBERON_0004535	http://purl.obolibrary.org/obo/UPHENO_0080362
diff --git a/src/curation/upheno-fillers/hp/abnormalBehavior.tsv b/src/curation/upheno-fillers/hp/abnormalBehavior.tsv
new file mode 100644
index 00000000..2510db43
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormalBehavior.tsv
@@ -0,0 +1,21 @@
+behavior_process	defined_class
+http://purl.obolibrary.org/obo/NBO_0000444	http://purl.obolibrary.org/obo/UPHENO_0079828
+http://purl.obolibrary.org/obo/NBO_0000015	http://purl.obolibrary.org/obo/UPHENO_0079829
+http://purl.obolibrary.org/obo/NBO_0001786	http://purl.obolibrary.org/obo/UPHENO_0079830
+http://purl.obolibrary.org/obo/NBO_0000313	http://purl.obolibrary.org/obo/UPHENO_0079826
+http://purl.obolibrary.org/obo/NBO_0000446	http://purl.obolibrary.org/obo/UPHENO_0079831
+http://purl.obolibrary.org/obo/NBO_0000018	http://purl.obolibrary.org/obo/UPHENO_0079832
+http://purl.obolibrary.org/obo/NBO_0000403	http://purl.obolibrary.org/obo/UPHENO_0079833
+http://purl.obolibrary.org/obo/NBO_0000128	http://purl.obolibrary.org/obo/UPHENO_0079834
+http://purl.obolibrary.org/obo/NBO_0001845	http://purl.obolibrary.org/obo/UPHENO_0079835
+http://purl.obolibrary.org/obo/NBO_0000129	http://purl.obolibrary.org/obo/UPHENO_0079836
+http://purl.obolibrary.org/obo/NBO_0000416	http://purl.obolibrary.org/obo/UPHENO_0079837
+http://purl.obolibrary.org/obo/NBO_0000119	http://purl.obolibrary.org/obo/UPHENO_0079838
+http://purl.obolibrary.org/obo/NBO_0000417	http://purl.obolibrary.org/obo/UPHENO_0079839
+http://purl.obolibrary.org/obo/NBO_0000605	http://purl.obolibrary.org/obo/UPHENO_0079840
+http://purl.obolibrary.org/obo/NBO_0000617	http://purl.obolibrary.org/obo/UPHENO_0079841
+http://purl.obolibrary.org/obo/NBO_0000092	http://purl.obolibrary.org/obo/UPHENO_0079842
+http://purl.obolibrary.org/obo/NBO_0000054	http://purl.obolibrary.org/obo/UPHENO_0079843
+http://purl.obolibrary.org/obo/NBO_0000120	http://purl.obolibrary.org/obo/UPHENO_0079844
+http://purl.obolibrary.org/obo/NBO_0000011	http://purl.obolibrary.org/obo/UPHENO_0079845
+http://purl.obolibrary.org/obo/NBO_0000003	http://purl.obolibrary.org/obo/UPHENO_0079846
diff --git a/src/curation/upheno-fillers/hp/abnormalBiologicalProcess.tsv b/src/curation/upheno-fillers/hp/abnormalBiologicalProcess.tsv
new file mode 100644
index 00000000..b2b1a271
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormalBiologicalProcess.tsv
@@ -0,0 +1,86 @@
+biological_process	defined_class
+http://purl.obolibrary.org/obo/GO_0032602	http://purl.obolibrary.org/obo/UPHENO_0080590
+http://purl.obolibrary.org/obo/NBO_0000446	http://purl.obolibrary.org/obo/UPHENO_0078579
+http://purl.obolibrary.org/obo/NBO_0000403	http://purl.obolibrary.org/obo/UPHENO_0078622
+http://purl.obolibrary.org/obo/NBO_0000128	http://purl.obolibrary.org/obo/UPHENO_0080591
+http://purl.obolibrary.org/obo/GO_0006776	http://purl.obolibrary.org/obo/UPHENO_0078581
+http://purl.obolibrary.org/obo/NBO_0000444	http://purl.obolibrary.org/obo/UPHENO_0080581
+http://purl.obolibrary.org/obo/GO_0001764	http://purl.obolibrary.org/obo/UPHENO_0049852
+http://purl.obolibrary.org/obo/NBO_0000605	http://purl.obolibrary.org/obo/UPHENO_0080582
+http://purl.obolibrary.org/obo/GO_0070085	http://purl.obolibrary.org/obo/UPHENO_0078623
+http://purl.obolibrary.org/obo/NBO_0000129	http://purl.obolibrary.org/obo/UPHENO_0080592
+http://purl.obolibrary.org/obo/GO_0043084	http://purl.obolibrary.org/obo/UPHENO_0080583
+http://purl.obolibrary.org/obo/GO_0001843	http://purl.obolibrary.org/obo/UPHENO_0051077
+http://purl.obolibrary.org/obo/GO_0006693	http://purl.obolibrary.org/obo/UPHENO_0078624
+http://purl.obolibrary.org/obo/GO_0042593	http://purl.obolibrary.org/obo/UPHENO_0050433
+http://purl.obolibrary.org/obo/GO_0006493	http://purl.obolibrary.org/obo/UPHENO_0078583
+http://purl.obolibrary.org/obo/GO_0042110	http://purl.obolibrary.org/obo/UPHENO_0078625
+http://purl.obolibrary.org/obo/GO_0007268	http://purl.obolibrary.org/obo/UPHENO_0049907
+http://purl.obolibrary.org/obo/GO_0042552	http://purl.obolibrary.org/obo/UPHENO_0050406
+http://purl.obolibrary.org/obo/GO_0070527	http://purl.obolibrary.org/obo/UPHENO_0078627
+http://purl.obolibrary.org/obo/GO_0042755	http://purl.obolibrary.org/obo/UPHENO_0049798
+http://purl.obolibrary.org/obo/GO_0014831	http://purl.obolibrary.org/obo/UPHENO_0050696
+http://purl.obolibrary.org/obo/GO_0042359	http://purl.obolibrary.org/obo/UPHENO_0078628
+http://purl.obolibrary.org/obo/GO_0042756	http://purl.obolibrary.org/obo/UPHENO_0078629
+http://purl.obolibrary.org/obo/GO_0008283	http://purl.obolibrary.org/obo/UPHENO_0049858
+http://purl.obolibrary.org/obo/GO_0042713	http://purl.obolibrary.org/obo/UPHENO_0078585
+http://purl.obolibrary.org/obo/NBO_0000092	http://purl.obolibrary.org/obo/UPHENO_0080593
+http://purl.obolibrary.org/obo/GO_0050892	http://purl.obolibrary.org/obo/UPHENO_0078630
+http://purl.obolibrary.org/obo/NBO_0000054	http://purl.obolibrary.org/obo/UPHENO_0080584
+http://purl.obolibrary.org/obo/GO_0030261	http://purl.obolibrary.org/obo/UPHENO_0049918
+http://purl.obolibrary.org/obo/NBO_0000011	http://purl.obolibrary.org/obo/UPHENO_0080594
+http://purl.obolibrary.org/obo/GO_0003014	http://purl.obolibrary.org/obo/UPHENO_0051191
+http://purl.obolibrary.org/obo/GO_0006766	http://purl.obolibrary.org/obo/UPHENO_0078589
+http://purl.obolibrary.org/obo/GO_0006687	http://purl.obolibrary.org/obo/UPHENO_0051153
+http://purl.obolibrary.org/obo/NBO_0000313	http://purl.obolibrary.org/obo/UPHENO_0080585
+http://purl.obolibrary.org/obo/GO_0022011	http://purl.obolibrary.org/obo/UPHENO_0050370
+http://purl.obolibrary.org/obo/GO_0022010	http://purl.obolibrary.org/obo/UPHENO_0050372
+http://purl.obolibrary.org/obo/NBO_0001845	http://purl.obolibrary.org/obo/UPHENO_0080595
+http://purl.obolibrary.org/obo/GO_0072350	http://purl.obolibrary.org/obo/UPHENO_0078590
+http://purl.obolibrary.org/obo/GO_0070293	http://purl.obolibrary.org/obo/UPHENO_0051280
+http://purl.obolibrary.org/obo/GO_0006801	http://purl.obolibrary.org/obo/UPHENO_0078591
+http://purl.obolibrary.org/obo/NBO_0000119	http://purl.obolibrary.org/obo/UPHENO_0080596
+http://purl.obolibrary.org/obo/GO_0046541	http://purl.obolibrary.org/obo/UPHENO_0078637
+http://purl.obolibrary.org/obo/GO_0042100	http://purl.obolibrary.org/obo/UPHENO_0078638
+http://purl.obolibrary.org/obo/GO_0006487	http://purl.obolibrary.org/obo/UPHENO_0078593
+http://purl.obolibrary.org/obo/GO_0006520	http://purl.obolibrary.org/obo/UPHENO_0051195
+http://purl.obolibrary.org/obo/GO_0003010	http://purl.obolibrary.org/obo/UPHENO_0051196
+http://purl.obolibrary.org/obo/GO_0006486	http://purl.obolibrary.org/obo/UPHENO_0078594
+http://purl.obolibrary.org/obo/GO_0009235	http://purl.obolibrary.org/obo/UPHENO_0078595
+http://purl.obolibrary.org/obo/GO_0042703	http://purl.obolibrary.org/obo/UPHENO_0078597
+http://purl.obolibrary.org/obo/GO_0040007	http://purl.obolibrary.org/obo/UPHENO_0049874
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UPHENO_0049587
+http://purl.obolibrary.org/obo/NBO_0000120	http://purl.obolibrary.org/obo/UPHENO_0080597
+http://purl.obolibrary.org/obo/NBO_0000003	http://purl.obolibrary.org/obo/UPHENO_0080598
+http://purl.obolibrary.org/obo/GO_0006954	http://purl.obolibrary.org/obo/UPHENO_0049584
+http://purl.obolibrary.org/obo/GO_0050878	http://purl.obolibrary.org/obo/UPHENO_0050619
+http://purl.obolibrary.org/obo/GO_0007601	http://purl.obolibrary.org/obo/UPHENO_0050622
+http://purl.obolibrary.org/obo/GO_1903510	http://purl.obolibrary.org/obo/UPHENO_0050655
+http://purl.obolibrary.org/obo/GO_0042098	http://purl.obolibrary.org/obo/UPHENO_0078600
+http://purl.obolibrary.org/obo/GO_0042373	http://purl.obolibrary.org/obo/UPHENO_0078601
+http://purl.obolibrary.org/obo/GO_0046651	http://purl.obolibrary.org/obo/UPHENO_0078645
+http://purl.obolibrary.org/obo/GO_0007049	http://purl.obolibrary.org/obo/UPHENO_0049952
+http://purl.obolibrary.org/obo/GO_0008015	http://purl.obolibrary.org/obo/UPHENO_0051097
+http://purl.obolibrary.org/obo/GO_0060464	http://purl.obolibrary.org/obo/UPHENO_0078603
+http://purl.obolibrary.org/obo/GO_0006281	http://purl.obolibrary.org/obo/UPHENO_0051124
+http://purl.obolibrary.org/obo/GO_0019221	http://purl.obolibrary.org/obo/UPHENO_0078604
+http://purl.obolibrary.org/obo/GO_0036066	http://purl.obolibrary.org/obo/UPHENO_0078605
+http://purl.obolibrary.org/obo/GO_0031052	http://purl.obolibrary.org/obo/UPHENO_0078606
+http://purl.obolibrary.org/obo/GO_0001573	http://purl.obolibrary.org/obo/UPHENO_0078647
+http://purl.obolibrary.org/obo/NBO_0000018	http://purl.obolibrary.org/obo/UPHENO_0080599
+http://purl.obolibrary.org/obo/NBO_0000015	http://purl.obolibrary.org/obo/UPHENO_0080600
+http://purl.obolibrary.org/obo/NBO_0001786	http://purl.obolibrary.org/obo/UPHENO_0080586
+http://purl.obolibrary.org/obo/NBO_0000417	http://purl.obolibrary.org/obo/UPHENO_0080601
+http://purl.obolibrary.org/obo/GO_1903509	http://purl.obolibrary.org/obo/UPHENO_0050662
+http://purl.obolibrary.org/obo/NBO_0000416	http://purl.obolibrary.org/obo/UPHENO_0080602
+http://purl.obolibrary.org/obo/GO_0042360	http://purl.obolibrary.org/obo/UPHENO_0078612
+http://purl.obolibrary.org/obo/NBO_0000617	http://purl.obolibrary.org/obo/UPHENO_0080587
+http://purl.obolibrary.org/obo/GO_0006664	http://purl.obolibrary.org/obo/UPHENO_0050928
+http://purl.obolibrary.org/obo/GO_0007598	http://purl.obolibrary.org/obo/UPHENO_0078613
+http://purl.obolibrary.org/obo/GO_0060073	http://purl.obolibrary.org/obo/UPHENO_0078615
+http://purl.obolibrary.org/obo/GO_0007597	http://purl.obolibrary.org/obo/UPHENO_0078617
+http://purl.obolibrary.org/obo/GO_0030252	http://purl.obolibrary.org/obo/UPHENO_0080588
+http://purl.obolibrary.org/obo/GO_0001659	http://purl.obolibrary.org/obo/UPHENO_0078619
+http://purl.obolibrary.org/obo/GO_0072377	http://purl.obolibrary.org/obo/UPHENO_0078649
+http://purl.obolibrary.org/obo/GO_0001816	http://purl.obolibrary.org/obo/UPHENO_0080589
+http://purl.obolibrary.org/obo/GO_0019852	http://purl.obolibrary.org/obo/UPHENO_0078620
diff --git a/src/curation/upheno-fillers/hp/abnormalBiologicalProcessInLocation.tsv b/src/curation/upheno-fillers/hp/abnormalBiologicalProcessInLocation.tsv
new file mode 100644
index 00000000..af6d320d
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormalBiologicalProcessInLocation.tsv
@@ -0,0 +1,5 @@
+biological_process	location	defined_class
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0001555	http://purl.obolibrary.org/obo/UPHENO_0081978
+http://purl.obolibrary.org/obo/GO_0030432	http://purl.obolibrary.org/obo/UBERON_0001555	http://purl.obolibrary.org/obo/UPHENO_0081979
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/GO_0005746	http://purl.obolibrary.org/obo/UPHENO_0078404
+http://purl.obolibrary.org/obo/GO_0008152	http://purl.obolibrary.org/obo/GO_0005746	http://purl.obolibrary.org/obo/UPHENO_0078405
diff --git a/src/curation/upheno-fillers/hp/abnormalCellularComponent.tsv b/src/curation/upheno-fillers/hp/abnormalCellularComponent.tsv
new file mode 100644
index 00000000..1868d8cc
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormalCellularComponent.tsv
@@ -0,0 +1,3 @@
+cellular_component	defined_class
+http://purl.obolibrary.org/obo/GO_0005739	http://purl.obolibrary.org/obo/UPHENO_0082544
+http://purl.obolibrary.org/obo/GO_0005575	http://purl.obolibrary.org/obo/UPHENO_0006889
diff --git a/src/curation/upheno-fillers/hp/abnormalColorOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/hp/abnormalColorOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..4e4cefca
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormalColorOfAnatomicalEntity.tsv
@@ -0,0 +1,4 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0080210
+http://purl.obolibrary.org/obo/UBERON_0001091	http://purl.obolibrary.org/obo/UPHENO_0080215
+http://purl.obolibrary.org/obo/UBERON_0001088	http://purl.obolibrary.org/obo/UPHENO_0080216
diff --git a/src/curation/upheno-fillers/hp/abnormalColorOfAnatomicalEntityByColor.tsv b/src/curation/upheno-fillers/hp/abnormalColorOfAnatomicalEntityByColor.tsv
new file mode 100644
index 00000000..6661e518
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormalColorOfAnatomicalEntityByColor.tsv
@@ -0,0 +1,23 @@
+color	entity	defined_class
+http://purl.obolibrary.org/obo/PATO_0000323	http://purl.obolibrary.org/obo/UBERON_0010163	http://purl.obolibrary.org/obo/UPHENO_0083453
+http://purl.obolibrary.org/obo/PATO_0000014	http://purl.obolibrary.org/obo/UBERON_0010163	http://purl.obolibrary.org/obo/UPHENO_0083454
+http://purl.obolibrary.org/obo/PATO_0000014	http://purl.obolibrary.org/obo/UBERON_0001702	http://purl.obolibrary.org/obo/UPHENO_0083455
+http://purl.obolibrary.org/obo/PATO_0000323	http://purl.obolibrary.org/obo/UBERON_0001702	http://purl.obolibrary.org/obo/UPHENO_0083456
+http://purl.obolibrary.org/obo/PATO_0000319	http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0083438
+http://purl.obolibrary.org/obo/PATO_0000014	http://purl.obolibrary.org/obo/UBERON_0001752	http://purl.obolibrary.org/obo/UPHENO_0083457
+http://purl.obolibrary.org/obo/PATO_0000322	http://purl.obolibrary.org/obo/UBERON_0001037	http://purl.obolibrary.org/obo/UPHENO_0083458
+http://purl.obolibrary.org/obo/PATO_0000014	http://purl.obolibrary.org/obo/UBERON_0001037	http://purl.obolibrary.org/obo/UPHENO_0083439
+http://purl.obolibrary.org/obo/PATO_0000319	http://purl.obolibrary.org/obo/UBERON_0002097	http://purl.obolibrary.org/obo/UPHENO_0083459
+http://purl.obolibrary.org/obo/PATO_0000950	http://purl.obolibrary.org/obo/UBERON_0001752	http://purl.obolibrary.org/obo/UPHENO_0083460
+http://purl.obolibrary.org/obo/PATO_0000320	http://purl.obolibrary.org/obo/UBERON_0001091	http://purl.obolibrary.org/obo/UPHENO_0083461
+http://purl.obolibrary.org/obo/PATO_0000014	http://purl.obolibrary.org/obo/UBERON_0001091	http://purl.obolibrary.org/obo/UPHENO_0083444
+http://purl.obolibrary.org/obo/PATO_0000320	http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0083462
+http://purl.obolibrary.org/obo/PATO_0000318	http://purl.obolibrary.org/obo/UBERON_0001088	http://purl.obolibrary.org/obo/UPHENO_0083463
+http://purl.obolibrary.org/obo/PATO_0000014	http://purl.obolibrary.org/obo/UBERON_0001088	http://purl.obolibrary.org/obo/UPHENO_0083447
+http://purl.obolibrary.org/obo/PATO_0000322	http://purl.obolibrary.org/obo/UBERON_0001088	http://purl.obolibrary.org/obo/UPHENO_0083446
+http://purl.obolibrary.org/obo/PATO_0000318	http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0083464
+http://purl.obolibrary.org/obo/PATO_0000014	http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0083450
+http://purl.obolibrary.org/obo/PATO_0000322	http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0083451
+http://purl.obolibrary.org/obo/PATO_0000014	http://purl.obolibrary.org/obo/UBERON_0002097	http://purl.obolibrary.org/obo/UPHENO_0083465
+http://purl.obolibrary.org/obo/PATO_0000950	http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0083466
+http://purl.obolibrary.org/obo/PATO_0000323	http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0083452
diff --git a/src/curation/upheno-fillers/hp/abnormalConstrictionOfAnatomicalEntity-modified.tsv b/src/curation/upheno-fillers/hp/abnormalConstrictionOfAnatomicalEntity-modified.tsv
new file mode 100644
index 00000000..2f31cd95
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormalConstrictionOfAnatomicalEntity-modified.tsv
@@ -0,0 +1,31 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001351	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002289	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002146	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001771	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0014542	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0014543	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0010425	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002392	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001184	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0010746	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002291	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002137	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0000057	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002114	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0003126	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0000159	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001423	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001621	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002012	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001165	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001021	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002135	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0000199	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001737	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0000947	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0000941	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001637	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001516	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0011566	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/hp/abnormalConstrictionOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/hp/abnormalConstrictionOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..e5d03067
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormalConstrictionOfAnatomicalEntity.tsv
@@ -0,0 +1,5 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0081834
+http://purl.obolibrary.org/obo/UBERON_0002407	http://purl.obolibrary.org/obo/UPHENO_0081860
+http://purl.obolibrary.org/obo/UBERON_0002134	http://purl.obolibrary.org/obo/UPHENO_0081853
+http://purl.obolibrary.org/obo/UBERON_0000056	http://purl.obolibrary.org/obo/UPHENO_0081854
diff --git a/src/curation/upheno-fillers/hp/abnormalDegenerationOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/hp/abnormalDegenerationOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..ec3bd92d
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormalDegenerationOfAnatomicalEntity.tsv
@@ -0,0 +1,15 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0073937
+http://purl.obolibrary.org/obo/CL_0000100	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001017	http://purl.obolibrary.org/obo/UPHENO_0074047
+http://purl.obolibrary.org/obo/UBERON_0001875	http://purl.obolibrary.org/obo/UPHENO_0074034
+http://purl.obolibrary.org/obo/UBERON_0002589	http://purl.obolibrary.org/obo/UPHENO_0074049
+http://purl.obolibrary.org/obo/UBERON_0002435	http://purl.obolibrary.org/obo/UPHENO_0074039
+http://purl.obolibrary.org/obo/UBERON_0001066	http://purl.obolibrary.org/obo/UPHENO_0073944
+http://purl.obolibrary.org/obo/UBERON_0001893	http://purl.obolibrary.org/obo/UPHENO_0074132
+http://purl.obolibrary.org/obo/CL_0007011	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001844	http://purl.obolibrary.org/obo/UPHENO_0073963
+http://purl.obolibrary.org/obo/UBERON_0001954	http://purl.obolibrary.org/obo/UPHENO_0074055
+http://purl.obolibrary.org/obo/UBERON_0000964	http://purl.obolibrary.org/obo/UPHENO_0074000
+http://purl.obolibrary.org/obo/UBERON_0002107	http://purl.obolibrary.org/obo/UPHENO_0074001
+http://purl.obolibrary.org/obo/UBERON_0002437	http://purl.obolibrary.org/obo/UPHENO_0074037
diff --git a/src/curation/upheno-fillers/hp/abnormalDegenerationOfAnatomicalEntityInLocation.tsv b/src/curation/upheno-fillers/hp/abnormalDegenerationOfAnatomicalEntityInLocation.tsv
new file mode 100644
index 00000000..f4c5f980
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormalDegenerationOfAnatomicalEntityInLocation.tsv
@@ -0,0 +1,5 @@
+anatomical_entity	location	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0001017	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0043209	http://purl.obolibrary.org/obo/UBERON_0001017	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0043209	http://purl.obolibrary.org/obo/UBERON_0000010	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0000010	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/hp/abnormalDegenerationOfCellularComponentInLocation.tsv b/src/curation/upheno-fillers/hp/abnormalDegenerationOfCellularComponentInLocation.tsv
new file mode 100644
index 00000000..9e40630f
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormalDegenerationOfCellularComponentInLocation.tsv
@@ -0,0 +1,5 @@
+cellular_component	location	defined_class
+http://purl.obolibrary.org/obo/GO_0043209	http://purl.obolibrary.org/obo/UBERON_0000010	http://purl.obolibrary.org/obo/UPHENO_0076913
+http://purl.obolibrary.org/obo/GO_0043209	http://purl.obolibrary.org/obo/UBERON_0001017	http://purl.obolibrary.org/obo/UPHENO_0076914
+http://purl.obolibrary.org/obo/GO_0005575	http://purl.obolibrary.org/obo/UBERON_0001017	http://purl.obolibrary.org/obo/UPHENO_0076915
+http://purl.obolibrary.org/obo/GO_0005575	http://purl.obolibrary.org/obo/UBERON_0000010	http://purl.obolibrary.org/obo/UPHENO_0076917
diff --git a/src/curation/upheno-fillers/hp/abnormalFunctionalityOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/hp/abnormalFunctionalityOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..6367fc61
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormalFunctionalityOfAnatomicalEntity.tsv
@@ -0,0 +1,66 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0035639	http://purl.obolibrary.org/obo/UPHENO_0002456
+http://purl.obolibrary.org/obo/UBERON_0001630	http://purl.obolibrary.org/obo/UPHENO_0002320
+http://purl.obolibrary.org/obo/UBERON_0002204	http://purl.obolibrary.org/obo/UPHENO_0081440
+http://purl.obolibrary.org/obo/UBERON_0002369	http://purl.obolibrary.org/obo/UPHENO_0002391
+http://purl.obolibrary.org/obo/CL_0000084	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002046	http://purl.obolibrary.org/obo/UPHENO_0002325
+http://purl.obolibrary.org/obo/UBERON_0001905	http://purl.obolibrary.org/obo/UPHENO_0002214
+http://purl.obolibrary.org/obo/UBERON_0000017	http://purl.obolibrary.org/obo/UPHENO_0002216
+http://purl.obolibrary.org/obo/UBERON_0000019	http://purl.obolibrary.org/obo/UPHENO_0002219
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0002332
+http://purl.obolibrary.org/obo/UBERON_0004054	http://purl.obolibrary.org/obo/UPHENO_0078729
+http://purl.obolibrary.org/obo/CL_0000775	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001785	http://purl.obolibrary.org/obo/UPHENO_0078730
+http://purl.obolibrary.org/obo/UBERON_0001982	http://purl.obolibrary.org/obo/UPHENO_0002462
+http://purl.obolibrary.org/obo/UBERON_0000059	http://purl.obolibrary.org/obo/UPHENO_0078731
+http://purl.obolibrary.org/obo/UBERON_0004535	http://purl.obolibrary.org/obo/UPHENO_0002406
+http://purl.obolibrary.org/obo/UBERON_0000016	http://purl.obolibrary.org/obo/UPHENO_0002230
+http://purl.obolibrary.org/obo/UBERON_0001264	http://purl.obolibrary.org/obo/UPHENO_0002408
+http://purl.obolibrary.org/obo/UBERON_0002110	http://purl.obolibrary.org/obo/UPHENO_0002409
+http://purl.obolibrary.org/obo/UBERON_0000010	http://purl.obolibrary.org/obo/UPHENO_0002463
+http://purl.obolibrary.org/obo/UBERON_0002113	http://purl.obolibrary.org/obo/UPHENO_0002411
+http://purl.obolibrary.org/obo/UBERON_0001737	http://purl.obolibrary.org/obo/UPHENO_0078732
+http://purl.obolibrary.org/obo/UBERON_0001898	http://purl.obolibrary.org/obo/UPHENO_0002291
+http://purl.obolibrary.org/obo/UBERON_0007798	http://purl.obolibrary.org/obo/UPHENO_0002466
+http://purl.obolibrary.org/obo/UBERON_0001173	http://purl.obolibrary.org/obo/UPHENO_0002468
+http://purl.obolibrary.org/obo/UBERON_0002185	http://purl.obolibrary.org/obo/UPHENO_0078733
+http://purl.obolibrary.org/obo/UBERON_0001690	http://purl.obolibrary.org/obo/UPHENO_0002240
+http://purl.obolibrary.org/obo/UBERON_0002423	http://purl.obolibrary.org/obo/UPHENO_0002242
+http://purl.obolibrary.org/obo/UBERON_0002106	http://purl.obolibrary.org/obo/UPHENO_0002432
+http://purl.obolibrary.org/obo/UBERON_0001016	http://purl.obolibrary.org/obo/UPHENO_0002433
+http://purl.obolibrary.org/obo/UBERON_0001132	http://purl.obolibrary.org/obo/UPHENO_0002434
+http://purl.obolibrary.org/obo/UBERON_0000165	http://purl.obolibrary.org/obo/UPHENO_0078734
+http://purl.obolibrary.org/obo/UBERON_0001255	http://purl.obolibrary.org/obo/UPHENO_0002437
+http://purl.obolibrary.org/obo/UBERON_0001771	http://purl.obolibrary.org/obo/UPHENO_0002469
+http://purl.obolibrary.org/obo/UBERON_0003706	http://purl.obolibrary.org/obo/UPHENO_0078735
+http://purl.obolibrary.org/obo/UBERON_0001008	http://purl.obolibrary.org/obo/UPHENO_0002442
+http://purl.obolibrary.org/obo/UBERON_0001007	http://purl.obolibrary.org/obo/UPHENO_0002443
+http://purl.obolibrary.org/obo/UBERON_0005409	http://purl.obolibrary.org/obo/UPHENO_0002471
+http://purl.obolibrary.org/obo/UBERON_0001846	http://purl.obolibrary.org/obo/UPHENO_0078736
+http://purl.obolibrary.org/obo/CL_0000623	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000232	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002097	http://purl.obolibrary.org/obo/UPHENO_0078737
+http://purl.obolibrary.org/obo/CL_0000233	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000236	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002137	http://purl.obolibrary.org/obo/UPHENO_0078738
+http://purl.obolibrary.org/obo/UBERON_0000079	http://purl.obolibrary.org/obo/UPHENO_0002371
+http://purl.obolibrary.org/obo/UBERON_0000992	http://purl.obolibrary.org/obo/UPHENO_0002372
+http://purl.obolibrary.org/obo/UBERON_0002016	http://purl.obolibrary.org/obo/UPHENO_0002472
+http://purl.obolibrary.org/obo/UBERON_0001004	http://purl.obolibrary.org/obo/UPHENO_0002448
+http://purl.obolibrary.org/obo/UBERON_0002133	http://purl.obolibrary.org/obo/UPHENO_0002517
+http://purl.obolibrary.org/obo/UBERON_0001043	http://purl.obolibrary.org/obo/UPHENO_0002474
+http://purl.obolibrary.org/obo/GO_0031594	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002410	http://purl.obolibrary.org/obo/UPHENO_0002259
+http://purl.obolibrary.org/obo/UBERON_0002135	http://purl.obolibrary.org/obo/UPHENO_0078739
+http://purl.obolibrary.org/obo/UBERON_0000990	http://purl.obolibrary.org/obo/UPHENO_0002378
+http://purl.obolibrary.org/obo/UBERON_0000474	http://purl.obolibrary.org/obo/UPHENO_0002262
+http://purl.obolibrary.org/obo/UBERON_0002134	http://purl.obolibrary.org/obo/UPHENO_0078740
+http://purl.obolibrary.org/obo/UBERON_0001638	http://purl.obolibrary.org/obo/UPHENO_0002475
+http://purl.obolibrary.org/obo/UBERON_0000947	http://purl.obolibrary.org/obo/UPHENO_0078741
+http://purl.obolibrary.org/obo/UBERON_0002405	http://purl.obolibrary.org/obo/UPHENO_0002263
+http://purl.obolibrary.org/obo/UBERON_0001756	http://purl.obolibrary.org/obo/UPHENO_0002476
+http://purl.obolibrary.org/obo/UBERON_0001711	http://purl.obolibrary.org/obo/UPHENO_0078742
+http://purl.obolibrary.org/obo/UBERON_0001637	http://purl.obolibrary.org/obo/UPHENO_0002477
+http://purl.obolibrary.org/obo/GO_0005764	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0000949	http://purl.obolibrary.org/obo/UPHENO_0078743
diff --git a/src/curation/upheno-fillers/hp/abnormalFunctionalityOfCellularComponent.tsv b/src/curation/upheno-fillers/hp/abnormalFunctionalityOfCellularComponent.tsv
new file mode 100644
index 00000000..75291fce
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormalFunctionalityOfCellularComponent.tsv
@@ -0,0 +1,4 @@
+cellular_component	defined_class
+http://purl.obolibrary.org/obo/GO_0031594	http://purl.obolibrary.org/obo/UPHENO_0076896
+http://purl.obolibrary.org/obo/GO_0005575	http://purl.obolibrary.org/obo/UPHENO_0010743
+http://purl.obolibrary.org/obo/GO_0005764	http://purl.obolibrary.org/obo/UPHENO_0010747
diff --git a/src/curation/upheno-fillers/hp/abnormalFunctionalityOfPartOfAnatomicalEntity-modified.tsv b/src/curation/upheno-fillers/hp/abnormalFunctionalityOfPartOfAnatomicalEntity-modified.tsv
new file mode 100644
index 00000000..3a744c2c
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormalFunctionalityOfPartOfAnatomicalEntity-modified.tsv
@@ -0,0 +1,66 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0035639	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001630	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002204	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002369	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000084	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002046	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001905	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0000017	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0000019	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0004054	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000775	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001785	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001982	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0000059	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0004535	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0000016	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001264	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002110	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0000010	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002113	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001737	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001898	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0007798	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001173	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002185	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001690	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002423	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002106	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001016	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001132	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0000165	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001255	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001771	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0003706	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001008	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001007	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0005409	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001846	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000623	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000232	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002097	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000233	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000236	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002137	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0000079	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0000992	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002016	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001004	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002133	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001043	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0031594	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002410	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002135	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0000990	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0000474	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002134	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001638	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0000947	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002405	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001756	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001711	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001637	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0005764	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0000949	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/hp/abnormalFunctionalityOfPartOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/hp/abnormalFunctionalityOfPartOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..c96babb3
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormalFunctionalityOfPartOfAnatomicalEntity.tsv
@@ -0,0 +1,8 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0082875
+http://purl.obolibrary.org/obo/UBERON_0001042	http://purl.obolibrary.org/obo/UPHENO_0082876
+http://purl.obolibrary.org/obo/UBERON_0000310	http://purl.obolibrary.org/obo/UPHENO_0082877
+http://purl.obolibrary.org/obo/UBERON_0001245	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001465	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0004454	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0000056	http://purl.obolibrary.org/obo/UPHENO_0082878
diff --git a/src/curation/upheno-fillers/hp/abnormalHasExtraPartsOfTypeAnatomicalEntity.tsv b/src/curation/upheno-fillers/hp/abnormalHasExtraPartsOfTypeAnatomicalEntity.tsv
new file mode 100644
index 00000000..33906dde
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormalHasExtraPartsOfTypeAnatomicalEntity.tsv
@@ -0,0 +1,4 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0046217
+http://purl.obolibrary.org/obo/UBERON_0002384	http://purl.obolibrary.org/obo/UPHENO_0046226
+http://purl.obolibrary.org/obo/UBERON_0001013	http://purl.obolibrary.org/obo/UPHENO_0046229
diff --git a/src/curation/upheno-fillers/hp/abnormalHasExtraPartsOfTypeAnatomicalEntityInLocation.tsv b/src/curation/upheno-fillers/hp/abnormalHasExtraPartsOfTypeAnatomicalEntityInLocation.tsv
new file mode 100644
index 00000000..e29b0ea2
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormalHasExtraPartsOfTypeAnatomicalEntityInLocation.tsv
@@ -0,0 +1,13 @@
+anatomical_entity	location	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0001017	http://purl.obolibrary.org/obo/UPHENO_0046101
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0002100	http://purl.obolibrary.org/obo/UPHENO_0046103
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0000010	http://purl.obolibrary.org/obo/UPHENO_0046085
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0001015	http://purl.obolibrary.org/obo/UPHENO_0046104
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0000974	http://purl.obolibrary.org/obo/UPHENO_0046076
+http://purl.obolibrary.org/obo/UBERON_0001013	http://purl.obolibrary.org/obo/UBERON_0000974	http://purl.obolibrary.org/obo/UPHENO_0046126
+http://purl.obolibrary.org/obo/UBERON_0002190	http://purl.obolibrary.org/obo/UBERON_0002100	http://purl.obolibrary.org/obo/UPHENO_0046106
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0000916	http://purl.obolibrary.org/obo/UPHENO_0046127
+http://purl.obolibrary.org/obo/UBERON_0001013	http://purl.obolibrary.org/obo/UBERON_0000916	http://purl.obolibrary.org/obo/UPHENO_0046110
+http://purl.obolibrary.org/obo/UBERON_0001013	http://purl.obolibrary.org/obo/UBERON_0001015	http://purl.obolibrary.org/obo/UPHENO_0046097
+http://purl.obolibrary.org/obo/UBERON_0000345	http://purl.obolibrary.org/obo/UBERON_0000010	http://purl.obolibrary.org/obo/UPHENO_0046114
+http://purl.obolibrary.org/obo/UBERON_0000345	http://purl.obolibrary.org/obo/UBERON_0001017	http://purl.obolibrary.org/obo/UPHENO_0046134
diff --git a/src/curation/upheno-fillers/hp/abnormalHeightOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/hp/abnormalHeightOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..1116a43b
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormalHeightOfAnatomicalEntity.tsv
@@ -0,0 +1,3 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0081423
+http://purl.obolibrary.org/obo/UBERON_0000468	http://purl.obolibrary.org/obo/UPHENO_0081424
diff --git a/src/curation/upheno-fillers/hp/abnormalLengthOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/hp/abnormalLengthOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..b9e07b01
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormalLengthOfAnatomicalEntity.tsv
@@ -0,0 +1,4 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002336	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0013771	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/hp/abnormalLevelOfChemicalEntity.tsv b/src/curation/upheno-fillers/hp/abnormalLevelOfChemicalEntity.tsv
new file mode 100644
index 00000000..44903bcd
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormalLevelOfChemicalEntity.tsv
@@ -0,0 +1,6 @@
+chemical_entity	defined_class
+http://purl.obolibrary.org/obo/CHEBI_24431	http://purl.obolibrary.org/obo/UPHENO_0046284
+http://purl.obolibrary.org/obo/PR_Q15848	http://purl.obolibrary.org/obo/UPHENO_0081775
+http://purl.obolibrary.org/obo/PR_000007749	http://purl.obolibrary.org/obo/UPHENO_0046382
+http://purl.obolibrary.org/obo/CHEBI_546807	http://purl.obolibrary.org/obo/UPHENO_0046381
+http://purl.obolibrary.org/obo/PR_000003968	http://purl.obolibrary.org/obo/UPHENO_0081777
diff --git a/src/curation/upheno-fillers/hp/abnormalLevelOfChemicalEntityInLocation.tsv b/src/curation/upheno-fillers/hp/abnormalLevelOfChemicalEntityInLocation.tsv
new file mode 100644
index 00000000..588725e3
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormalLevelOfChemicalEntityInLocation.tsv
@@ -0,0 +1,213 @@
+chemical_entity	location	defined_class
+http://purl.obolibrary.org/obo/CHEBI_25017	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0051582
+http://purl.obolibrary.org/obo/CHEBI_28087	http://purl.obolibrary.org/obo/UBERON_0002107	http://purl.obolibrary.org/obo/UPHENO_0051584
+http://purl.obolibrary.org/obo/CHEBI_24431	http://purl.obolibrary.org/obo/UBERON_0001630	http://purl.obolibrary.org/obo/UPHENO_0051587
+http://purl.obolibrary.org/obo/CHEBI_5520	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0051905
+http://purl.obolibrary.org/obo/CHEBI_17026	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0051589
+http://purl.obolibrary.org/obo/CHEBI_33856	http://purl.obolibrary.org/obo/UBERON_0001359	http://purl.obolibrary.org/obo/UPHENO_0051906
+http://purl.obolibrary.org/obo/CHEBI_24431	http://purl.obolibrary.org/obo/CL_0000738	http://purl.obolibrary.org/obo/UPHENO_0051908
+http://purl.obolibrary.org/obo/CHEBI_17754	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0051597
+http://purl.obolibrary.org/obo/CHEBI_26650	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0051909
+http://purl.obolibrary.org/obo/CHEBI_28694	http://purl.obolibrary.org/obo/UBERON_0001088	http://purl.obolibrary.org/obo/UPHENO_0051910
+http://purl.obolibrary.org/obo/CHEBI_18248	http://purl.obolibrary.org/obo/UBERON_0001977	http://purl.obolibrary.org/obo/UPHENO_0051913
+http://purl.obolibrary.org/obo/CHEBI_33567	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0051914
+http://purl.obolibrary.org/obo/CHEBI_27208	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CHEBI_18291	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CHEBI_24610	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0051916
+http://purl.obolibrary.org/obo/CHEBI_27226	http://purl.obolibrary.org/obo/UBERON_0001088	http://purl.obolibrary.org/obo/UPHENO_0051608
+http://purl.obolibrary.org/obo/CHEBI_3098	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0051917
+http://purl.obolibrary.org/obo/CHEBI_3892	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0051918
+http://purl.obolibrary.org/obo/CHEBI_16541	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0051612
+http://purl.obolibrary.org/obo/CHEBI_26650	http://purl.obolibrary.org/obo/UBERON_0001359	http://purl.obolibrary.org/obo/UPHENO_0051919
+http://purl.obolibrary.org/obo/CHEBI_17196	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0051920
+http://purl.obolibrary.org/obo/CHEBI_23965	http://purl.obolibrary.org/obo/UBERON_0001977	http://purl.obolibrary.org/obo/UPHENO_0051921
+http://purl.obolibrary.org/obo/CHEBI_17544	http://purl.obolibrary.org/obo/UBERON_0001088	http://purl.obolibrary.org/obo/UPHENO_0051619
+http://purl.obolibrary.org/obo/CHEBI_26463	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0051923
+http://purl.obolibrary.org/obo/CHEBI_17822	http://purl.obolibrary.org/obo/UBERON_0001359	http://purl.obolibrary.org/obo/UPHENO_0051924
+http://purl.obolibrary.org/obo/CHEBI_18237	http://purl.obolibrary.org/obo/UBERON_0001359	http://purl.obolibrary.org/obo/UPHENO_0051925
+http://purl.obolibrary.org/obo/CHEBI_28868	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CHEBI_27897	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CHEBI_22881	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0077814
+http://purl.obolibrary.org/obo/CHEBI_18059	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0051628
+http://purl.obolibrary.org/obo/CHEBI_26463	http://purl.obolibrary.org/obo/UBERON_0001359	http://purl.obolibrary.org/obo/UPHENO_0051931
+http://purl.obolibrary.org/obo/CHEBI_24431	http://purl.obolibrary.org/obo/UBERON_0001969	http://purl.obolibrary.org/obo/UPHENO_0051630
+http://purl.obolibrary.org/obo/CHEBI_16526	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0077815
+http://purl.obolibrary.org/obo/CHEBI_16646	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CHEBI_15318	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CHEBI_25017	http://purl.obolibrary.org/obo/UBERON_0001359	http://purl.obolibrary.org/obo/UPHENO_0051934
+http://purl.obolibrary.org/obo/CHEBI_24431	http://purl.obolibrary.org/obo/CL_0008002	http://purl.obolibrary.org/obo/UPHENO_0077816
+http://purl.obolibrary.org/obo/CHEBI_25384	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/PR_000009054	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0051638
+http://purl.obolibrary.org/obo/CHEBI_15904	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CHEBI_16947	http://purl.obolibrary.org/obo/UBERON_0001088	http://purl.obolibrary.org/obo/UPHENO_0051641
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diff --git a/src/curation/upheno-fillers/hp/abnormalLevelOfChemicalEntityWithRoleInLocation.tsv b/src/curation/upheno-fillers/hp/abnormalLevelOfChemicalEntityWithRoleInLocation.tsv
new file mode 100644
index 00000000..1969d819
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormalLevelOfChemicalEntityWithRoleInLocation.tsv
@@ -0,0 +1,12 @@
+location	role	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001088	http://purl.obolibrary.org/obo/CHEBI_24621	http://purl.obolibrary.org/obo/UPHENO_0081543
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diff --git a/src/curation/upheno-fillers/hp/abnormalMassDensityOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/hp/abnormalMassDensityOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..48e0ca18
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormalMassDensityOfAnatomicalEntity.tsv
@@ -0,0 +1,4 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0084653
+http://purl.obolibrary.org/obo/UBERON_0001447	http://purl.obolibrary.org/obo/UPHENO_0084655
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diff --git a/src/curation/upheno-fillers/hp/abnormalMorphologyOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/hp/abnormalMorphologyOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..05b83d57
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormalMorphologyOfAnatomicalEntity.tsv
@@ -0,0 +1,180 @@
+anatomical_entity	defined_class
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+http://purl.obolibrary.org/obo/UBERON_0014796	http://purl.obolibrary.org/obo/UPHENO_0021845
diff --git a/src/curation/upheno-fillers/hp/abnormalMorphologyOfAnatomicalEntityInLocation.tsv b/src/curation/upheno-fillers/hp/abnormalMorphologyOfAnatomicalEntityInLocation.tsv
new file mode 100644
index 00000000..5982024e
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormalMorphologyOfAnatomicalEntityInLocation.tsv
@@ -0,0 +1,36 @@
+anatomical_entity	location	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0001231	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002049	http://purl.obolibrary.org/obo/UBERON_0001811	http://purl.obolibrary.org/obo/UPHENO_0015306
+http://purl.obolibrary.org/obo/UBERON_0002389	http://purl.obolibrary.org/obo/UBERON_0002398	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001637	http://purl.obolibrary.org/obo/UBERON_0000966	http://purl.obolibrary.org/obo/UPHENO_0015278
+http://purl.obolibrary.org/obo/UBERON_0000982	http://purl.obolibrary.org/obo/UBERON_0010708	http://purl.obolibrary.org/obo/UPHENO_0079870
+http://purl.obolibrary.org/obo/UBERON_0001021	http://purl.obolibrary.org/obo/UBERON_0001846	http://purl.obolibrary.org/obo/UPHENO_0015310
+http://purl.obolibrary.org/obo/GO_0031514	http://purl.obolibrary.org/obo/UBERON_0001004	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0000966	http://purl.obolibrary.org/obo/UPHENO_0015314
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0012476	http://purl.obolibrary.org/obo/UPHENO_0079871
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+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0012475	http://purl.obolibrary.org/obo/UPHENO_0079872
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+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0008878	http://purl.obolibrary.org/obo/UPHENO_0081433
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diff --git a/src/curation/upheno-fillers/hp/abnormalMorphologyOfCellularComponent.tsv b/src/curation/upheno-fillers/hp/abnormalMorphologyOfCellularComponent.tsv
new file mode 100644
index 00000000..b38601a5
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormalMorphologyOfCellularComponent.tsv
@@ -0,0 +1,4 @@
+cellular_component	defined_class
+http://purl.obolibrary.org/obo/GO_0005739	http://purl.obolibrary.org/obo/UPHENO_0067707
+http://purl.obolibrary.org/obo/GO_0005575	http://purl.obolibrary.org/obo/UPHENO_0067691
+http://purl.obolibrary.org/obo/GO_0044307	http://purl.obolibrary.org/obo/UPHENO_0067729
diff --git a/src/curation/upheno-fillers/hp/abnormalMorphologyOfPartOfAnatomicalEntity-modified.tsv b/src/curation/upheno-fillers/hp/abnormalMorphologyOfPartOfAnatomicalEntity-modified.tsv
new file mode 100644
index 00000000..41bd84a5
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormalMorphologyOfPartOfAnatomicalEntity-modified.tsv
@@ -0,0 +1,179 @@
+anatomical_entity	defined_class
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+http://purl.obolibrary.org/obo/UBERON_0006003	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0006761	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001072	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0035639	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0005956	http://purl.obolibrary.org/obo/UPHENO_0084757
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+http://purl.obolibrary.org/obo/UBERON_0002048	http://purl.obolibrary.org/obo/UPHENO_0084757
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diff --git a/src/curation/upheno-fillers/hp/abnormalMorphologyOfPartOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/hp/abnormalMorphologyOfPartOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..aea0ed90
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormalMorphologyOfPartOfAnatomicalEntity.tsv
@@ -0,0 +1,305 @@
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+http://purl.obolibrary.org/obo/UBERON_0010887	http://purl.obolibrary.org/obo/UPHENO_0083649
+http://purl.obolibrary.org/obo/UBERON_0004096	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000775	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002115	http://purl.obolibrary.org/obo/UPHENO_0081591
+http://purl.obolibrary.org/obo/UBERON_0003689	http://purl.obolibrary.org/obo/UPHENO_0081592
+http://purl.obolibrary.org/obo/UBERON_0002114	http://purl.obolibrary.org/obo/UPHENO_0081594
+http://purl.obolibrary.org/obo/UBERON_0003687	http://purl.obolibrary.org/obo/UPHENO_0081595
+http://purl.obolibrary.org/obo/UBERON_0000059	http://purl.obolibrary.org/obo/UPHENO_0076773
+http://purl.obolibrary.org/obo/UBERON_0001820	http://purl.obolibrary.org/obo/UPHENO_0076774
+http://purl.obolibrary.org/obo/UBERON_0001269	http://purl.obolibrary.org/obo/UPHENO_0081596
+http://purl.obolibrary.org/obo/UBERON_0004535	http://purl.obolibrary.org/obo/UPHENO_0076776
+http://purl.obolibrary.org/obo/UBERON_0002358	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0000053	http://purl.obolibrary.org/obo/UPHENO_0076777
+http://purl.obolibrary.org/obo/UBERON_0002110	http://purl.obolibrary.org/obo/UPHENO_0076778
+http://purl.obolibrary.org/obo/CL_0000094	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002113	http://purl.obolibrary.org/obo/UPHENO_0076779
+http://purl.obolibrary.org/obo/UBERON_0004652	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0000056	http://purl.obolibrary.org/obo/UPHENO_0076780
+http://purl.obolibrary.org/obo/UBERON_0014693	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0004408	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002349	http://purl.obolibrary.org/obo/UPHENO_0076781
+http://purl.obolibrary.org/obo/UBERON_0002228	http://purl.obolibrary.org/obo/UPHENO_0083650
+http://purl.obolibrary.org/obo/UBERON_0000965	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0000966	http://purl.obolibrary.org/obo/UPHENO_0076782
+http://purl.obolibrary.org/obo/UBERON_0000160	http://purl.obolibrary.org/obo/UPHENO_0076783
+http://purl.obolibrary.org/obo/UBERON_0004089	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0004086	http://purl.obolibrary.org/obo/UPHENO_0081598
+http://purl.obolibrary.org/obo/CL_0000188	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0004084	http://purl.obolibrary.org/obo/UPHENO_0081599
+http://purl.obolibrary.org/obo/UBERON_0004085	http://purl.obolibrary.org/obo/UPHENO_0081600
+http://purl.obolibrary.org/obo/UBERON_0004646	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0000167	http://purl.obolibrary.org/obo/UPHENO_0076786
+http://purl.obolibrary.org/obo/UBERON_0003679	http://purl.obolibrary.org/obo/UPHENO_0076787
+http://purl.obolibrary.org/obo/UBERON_0002106	http://purl.obolibrary.org/obo/UPHENO_0076790
+http://purl.obolibrary.org/obo/UBERON_0001017	http://purl.obolibrary.org/obo/UPHENO_0076791
+http://purl.obolibrary.org/obo/UBERON_0007119	http://purl.obolibrary.org/obo/UPHENO_0081602
+http://purl.obolibrary.org/obo/UBERON_0001016	http://purl.obolibrary.org/obo/UPHENO_0076702
+http://purl.obolibrary.org/obo/UBERON_0006822	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001132	http://purl.obolibrary.org/obo/UPHENO_0076796
+http://purl.obolibrary.org/obo/UBERON_0001495	http://purl.obolibrary.org/obo/UPHENO_0076793
+http://purl.obolibrary.org/obo/UBERON_0007118	http://purl.obolibrary.org/obo/UPHENO_0076794
+http://purl.obolibrary.org/obo/UBERON_0001013	http://purl.obolibrary.org/obo/UPHENO_0076797
+http://purl.obolibrary.org/obo/UBERON_0000165	http://purl.obolibrary.org/obo/UPHENO_0076800
+http://purl.obolibrary.org/obo/UBERON_0000045	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0000956	http://purl.obolibrary.org/obo/UPHENO_0081603
+http://purl.obolibrary.org/obo/UBERON_0000959	http://purl.obolibrary.org/obo/UPHENO_0076802
+http://purl.obolibrary.org/obo/UBERON_0001007	http://purl.obolibrary.org/obo/UPHENO_0076803
+http://purl.obolibrary.org/obo/UBERON_0000955	http://purl.obolibrary.org/obo/UPHENO_0076805
+http://purl.obolibrary.org/obo/UBERON_0010742	http://purl.obolibrary.org/obo/UPHENO_0076806
+http://purl.obolibrary.org/obo/UBERON_0012128	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0010746	http://purl.obolibrary.org/obo/UPHENO_0081604
+http://purl.obolibrary.org/obo/UBERON_0001245	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0006813	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002336	http://purl.obolibrary.org/obo/UPHENO_0076807
+http://purl.obolibrary.org/obo/UBERON_0006810	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001486	http://purl.obolibrary.org/obo/UPHENO_0081608
+http://purl.obolibrary.org/obo/UBERON_0000945	http://purl.obolibrary.org/obo/UPHENO_0081609
+http://purl.obolibrary.org/obo/UBERON_0000946	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0000947	http://purl.obolibrary.org/obo/UPHENO_0076809
+http://purl.obolibrary.org/obo/UBERON_0000948	http://purl.obolibrary.org/obo/UPHENO_0076810
+http://purl.obolibrary.org/obo/UBERON_0000941	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001359	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0000029	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0000949	http://purl.obolibrary.org/obo/UPHENO_0076812
diff --git a/src/curation/upheno-fillers/hp/abnormalNumberOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/hp/abnormalNumberOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..71c79f1c
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormalNumberOfAnatomicalEntity.tsv
@@ -0,0 +1,19 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0011498
+http://purl.obolibrary.org/obo/UBERON_0001091	http://purl.obolibrary.org/obo/UPHENO_0011564
+http://purl.obolibrary.org/obo/CL_0000233	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000542	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000235	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000576	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000236	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000775	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000038	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001037	http://purl.obolibrary.org/obo/UPHENO_0011535
+http://purl.obolibrary.org/obo/UBERON_0001098	http://purl.obolibrary.org/obo/UPHENO_0011587
+http://purl.obolibrary.org/obo/CL_0000084	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0005739	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0007774	http://purl.obolibrary.org/obo/UPHENO_0011589
+http://purl.obolibrary.org/obo/UBERON_0014381	http://purl.obolibrary.org/obo/UPHENO_0011590
+http://purl.obolibrary.org/obo/CL_0000623	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000767	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000738	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/hp/abnormalNumberOfAnatomicalEntityInLocation.tsv b/src/curation/upheno-fillers/hp/abnormalNumberOfAnatomicalEntityInLocation.tsv
new file mode 100644
index 00000000..0216c52b
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormalNumberOfAnatomicalEntityInLocation.tsv
@@ -0,0 +1,3 @@
+anatomical_entity	location	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000771	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/hp/abnormalNumberOfCellularComponent.tsv b/src/curation/upheno-fillers/hp/abnormalNumberOfCellularComponent.tsv
new file mode 100644
index 00000000..5ddf22ee
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormalNumberOfCellularComponent.tsv
@@ -0,0 +1,3 @@
+cellular_component	defined_class
+http://purl.obolibrary.org/obo/GO_0005739	http://purl.obolibrary.org/obo/UPHENO_0046181
+http://purl.obolibrary.org/obo/GO_0005575	http://purl.obolibrary.org/obo/UPHENO_0046183
diff --git a/src/curation/upheno-fillers/hp/abnormalPersistenceOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/hp/abnormalPersistenceOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..99a0d4b7
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormalPersistenceOfAnatomicalEntity.tsv
@@ -0,0 +1,4 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0081971
+http://purl.obolibrary.org/obo/UBERON_0002270	http://purl.obolibrary.org/obo/UPHENO_0081972
+http://purl.obolibrary.org/obo/UBERON_0007116	http://purl.obolibrary.org/obo/UPHENO_0081973
diff --git a/src/curation/upheno-fillers/hp/abnormalPositionOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/hp/abnormalPositionOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..3fa0d774
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormalPositionOfAnatomicalEntity.tsv
@@ -0,0 +1,7 @@
+entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0010163	http://purl.obolibrary.org/obo/UPHENO_0018422
+http://purl.obolibrary.org/obo/UBERON_0010284	http://purl.obolibrary.org/obo/UPHENO_0018423
+http://purl.obolibrary.org/obo/UBERON_0010230	http://purl.obolibrary.org/obo/UPHENO_0018424
+http://purl.obolibrary.org/obo/UBERON_0014381	http://purl.obolibrary.org/obo/UPHENO_0018425
+http://purl.obolibrary.org/obo/UBERON_0001690	http://purl.obolibrary.org/obo/UPHENO_0018426
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0018390
diff --git a/src/curation/upheno-fillers/hp/abnormalProportionOfCellTypeInLocation.tsv b/src/curation/upheno-fillers/hp/abnormalProportionOfCellTypeInLocation.tsv
new file mode 100644
index 00000000..6d5dac7b
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormalProportionOfCellTypeInLocation.tsv
@@ -0,0 +1,3 @@
+cell	location	defined_class
+http://purl.obolibrary.org/obo/CL_0000792	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0081729
+http://purl.obolibrary.org/obo/CL_0000000	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0081730
diff --git a/src/curation/upheno-fillers/hp/abnormalProportionOfCellTypeTowardsCellTypeInLocation.tsv b/src/curation/upheno-fillers/hp/abnormalProportionOfCellTypeTowardsCellTypeInLocation.tsv
new file mode 100644
index 00000000..6d12405f
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormalProportionOfCellTypeTowardsCellTypeInLocation.tsv
@@ -0,0 +1,50 @@
+cell	compared_cell	location	defined_class
+http://purl.obolibrary.org/obo/CL_0001062	http://purl.obolibrary.org/obo/CL_0000084	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0080967
+http://purl.obolibrary.org/obo/CL_0000492	http://purl.obolibrary.org/obo/CL_0000000	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0080968
+http://purl.obolibrary.org/obo/CL_0000818	http://purl.obolibrary.org/obo/CL_0000236	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0080970
+http://purl.obolibrary.org/obo/CL_0000492	http://purl.obolibrary.org/obo/CL_0000084	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0080973
+http://purl.obolibrary.org/obo/CL_0000895	http://purl.obolibrary.org/obo/CL_0000000	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0080974
+http://purl.obolibrary.org/obo/CL_0000897	http://purl.obolibrary.org/obo/CL_0000084	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0080975
+http://purl.obolibrary.org/obo/CL_0000000	http://purl.obolibrary.org/obo/CL_0000236	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0080976
+http://purl.obolibrary.org/obo/CL_0000895	http://purl.obolibrary.org/obo/CL_0000084	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0080977
+http://purl.obolibrary.org/obo/CL_0001062	http://purl.obolibrary.org/obo/CL_0000000	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0080978
+http://purl.obolibrary.org/obo/CL_0000788	http://purl.obolibrary.org/obo/CL_0000000	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0080980
+http://purl.obolibrary.org/obo/CL_0000787	http://purl.obolibrary.org/obo/CL_0000000	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0080982
+http://purl.obolibrary.org/obo/CL_0000816	http://purl.obolibrary.org/obo/CL_0000236	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0080984
+http://purl.obolibrary.org/obo/CL_0011025	http://purl.obolibrary.org/obo/CL_0000084	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0080988
+http://purl.obolibrary.org/obo/CL_0000788	http://purl.obolibrary.org/obo/CL_0000236	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0080990
+http://purl.obolibrary.org/obo/CL_0000787	http://purl.obolibrary.org/obo/CL_0000236	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0080992
+http://purl.obolibrary.org/obo/CL_0011025	http://purl.obolibrary.org/obo/CL_0000000	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0080997
+http://purl.obolibrary.org/obo/CL_0000980	http://purl.obolibrary.org/obo/CL_0000236	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0080998
+http://purl.obolibrary.org/obo/CL_0001044	http://purl.obolibrary.org/obo/CL_0000000	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0080999
+http://purl.obolibrary.org/obo/CL_0001044	http://purl.obolibrary.org/obo/CL_0000084	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0081000
+http://purl.obolibrary.org/obo/CL_0000000	http://purl.obolibrary.org/obo/CL_0000084	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0081008
+http://purl.obolibrary.org/obo/CL_0000000	http://purl.obolibrary.org/obo/CL_0000000	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0081014
+http://purl.obolibrary.org/obo/CL_0000898	http://purl.obolibrary.org/obo/CL_0000000	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0081016
+http://purl.obolibrary.org/obo/CL_0000813	http://purl.obolibrary.org/obo/CL_0000000	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0081017
+http://purl.obolibrary.org/obo/CL_0000816	http://purl.obolibrary.org/obo/CL_0000000	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0081018
+http://purl.obolibrary.org/obo/CL_0000898	http://purl.obolibrary.org/obo/CL_0000084	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0081019
+http://purl.obolibrary.org/obo/CL_0000897	http://purl.obolibrary.org/obo/CL_0000000	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0081020
+http://purl.obolibrary.org/obo/CL_0000813	http://purl.obolibrary.org/obo/CL_0000084	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0081021
+http://purl.obolibrary.org/obo/CL_0000818	http://purl.obolibrary.org/obo/CL_0000000	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0081022
+http://purl.obolibrary.org/obo/CL_0000972	http://purl.obolibrary.org/obo/CL_0000000	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0081026
+http://purl.obolibrary.org/obo/CL_0000970	http://purl.obolibrary.org/obo/CL_0000000	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0081027
+http://purl.obolibrary.org/obo/CL_0000907	http://purl.obolibrary.org/obo/CL_0000084	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0081028
+http://purl.obolibrary.org/obo/CL_0000970	http://purl.obolibrary.org/obo/CL_0000236	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0081029
+http://purl.obolibrary.org/obo/CL_0000904	http://purl.obolibrary.org/obo/CL_0000000	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0081030
+http://purl.obolibrary.org/obo/CL_0000624	http://purl.obolibrary.org/obo/CL_0000000	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0081031
+http://purl.obolibrary.org/obo/CL_0000904	http://purl.obolibrary.org/obo/CL_0000084	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0081032
+http://purl.obolibrary.org/obo/CL_0000625	http://purl.obolibrary.org/obo/CL_0000000	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0081033
+http://purl.obolibrary.org/obo/CL_0000972	http://purl.obolibrary.org/obo/CL_0000236	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0081034
+http://purl.obolibrary.org/obo/CL_0000909	http://purl.obolibrary.org/obo/CL_0000000	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0081036
+http://purl.obolibrary.org/obo/CL_0000907	http://purl.obolibrary.org/obo/CL_0000000	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0081037
+http://purl.obolibrary.org/obo/CL_0000909	http://purl.obolibrary.org/obo/CL_0000084	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0081038
+http://purl.obolibrary.org/obo/CL_0000624	http://purl.obolibrary.org/obo/CL_0000084	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0081039
+http://purl.obolibrary.org/obo/CL_0000625	http://purl.obolibrary.org/obo/CL_0000084	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0081040
+http://purl.obolibrary.org/obo/CL_0000980	http://purl.obolibrary.org/obo/CL_0000000	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0081041
+http://purl.obolibrary.org/obo/CL_0000913	http://purl.obolibrary.org/obo/CL_0000084	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0081042
+http://purl.obolibrary.org/obo/CL_0000912	http://purl.obolibrary.org/obo/CL_0000000	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0081043
+http://purl.obolibrary.org/obo/CL_0000912	http://purl.obolibrary.org/obo/CL_0000084	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0081044
+http://purl.obolibrary.org/obo/CL_0000913	http://purl.obolibrary.org/obo/CL_0000000	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0081045
+http://purl.obolibrary.org/obo/CL_0000845	http://purl.obolibrary.org/obo/CL_0000000	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0081048
+http://purl.obolibrary.org/obo/CL_0000845	http://purl.obolibrary.org/obo/CL_0000236	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0081054
diff --git a/src/curation/upheno-fillers/hp/abnormalRateOfBiologicalProcess.tsv b/src/curation/upheno-fillers/hp/abnormalRateOfBiologicalProcess.tsv
new file mode 100644
index 00000000..123ddff9
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormalRateOfBiologicalProcess.tsv
@@ -0,0 +1,3 @@
+biological_process	defined_class
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UPHENO_0080377
+http://purl.obolibrary.org/obo/GO_0070227	http://purl.obolibrary.org/obo/UPHENO_0080381
diff --git a/src/curation/upheno-fillers/hp/abnormalRateOfBiologicalProcessInLocation.tsv b/src/curation/upheno-fillers/hp/abnormalRateOfBiologicalProcessInLocation.tsv
new file mode 100644
index 00000000..e1045be0
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormalRateOfBiologicalProcessInLocation.tsv
@@ -0,0 +1,3 @@
+biological_process	location	defined_class
+http://purl.obolibrary.org/obo/GO_0035878	http://purl.obolibrary.org/obo/UBERON_0001705	http://purl.obolibrary.org/obo/UPHENO_0080227
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0001705	http://purl.obolibrary.org/obo/UPHENO_0080228
diff --git a/src/curation/upheno-fillers/hp/abnormalShapeOfAnatomicalEntityByShapeType.tsv b/src/curation/upheno-fillers/hp/abnormalShapeOfAnatomicalEntityByShapeType.tsv
new file mode 100644
index 00000000..b16411d9
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormalShapeOfAnatomicalEntityByShapeType.tsv
@@ -0,0 +1,506 @@
+entity	shape	defined_class
+http://purl.obolibrary.org/obo/UBERON_0008200	http://purl.obolibrary.org/obo/PATO_0000407	http://purl.obolibrary.org/obo/UPHENO_0041025
+http://purl.obolibrary.org/obo/UBERON_0003451	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0041252
+http://purl.obolibrary.org/obo/UBERON_0001819	http://purl.obolibrary.org/obo/PATO_0001878	http://purl.obolibrary.org/obo/UPHENO_0041253
+http://purl.obolibrary.org/obo/UBERON_0001273	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0041254
+http://purl.obolibrary.org/obo/UBERON_0004316	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0041255
+http://purl.obolibrary.org/obo/UBERON_0003639	http://purl.obolibrary.org/obo/PATO_0002087	http://purl.obolibrary.org/obo/UPHENO_0041256
+http://purl.obolibrary.org/obo/UBERON_0004315	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0041257
+http://purl.obolibrary.org/obo/UBERON_0002495	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0041258
+http://purl.obolibrary.org/obo/UBERON_0004314	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0041259
+http://purl.obolibrary.org/obo/UBERON_0002374	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0041260
+http://purl.obolibrary.org/obo/UBERON_0005402	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0041261
+http://purl.obolibrary.org/obo/UBERON_0003636	http://purl.obolibrary.org/obo/PATO_0002087	http://purl.obolibrary.org/obo/UPHENO_0041262
+http://purl.obolibrary.org/obo/UBERON_0003637	http://purl.obolibrary.org/obo/PATO_0002087	http://purl.obolibrary.org/obo/UPHENO_0041263
+http://purl.obolibrary.org/obo/UBERON_0003638	http://purl.obolibrary.org/obo/PATO_0002087	http://purl.obolibrary.org/obo/UPHENO_0041264
+http://purl.obolibrary.org/obo/UBERON_0003466	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0041265
+http://purl.obolibrary.org/obo/UBERON_0004313	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0041266
+http://purl.obolibrary.org/obo/UBERON_0004312	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0041267
+http://purl.obolibrary.org/obo/UBERON_0002137	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0041042
+http://purl.obolibrary.org/obo/UBERON_0003650	http://purl.obolibrary.org/obo/PATO_0002087	http://purl.obolibrary.org/obo/UPHENO_0041268
+http://purl.obolibrary.org/obo/UBERON_0004311	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0041269
+http://purl.obolibrary.org/obo/UBERON_0003672	http://purl.obolibrary.org/obo/PATO_0002021	http://purl.obolibrary.org/obo/UPHENO_0041270
+http://purl.obolibrary.org/obo/UBERON_0004317	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0041271
+http://purl.obolibrary.org/obo/UBERON_0001424	http://purl.obolibrary.org/obo/PATO_0000944	http://purl.obolibrary.org/obo/UPHENO_0041272
+http://purl.obolibrary.org/obo/UBERON_0013748	http://purl.obolibrary.org/obo/PATO_0000944	http://purl.obolibrary.org/obo/UPHENO_0041273
+http://purl.obolibrary.org/obo/UBERON_0003645	http://purl.obolibrary.org/obo/PATO_0002087	http://purl.obolibrary.org/obo/UPHENO_0041274
+http://purl.obolibrary.org/obo/UBERON_0001449	http://purl.obolibrary.org/obo/PATO_0002087	http://purl.obolibrary.org/obo/UPHENO_0041275
+http://purl.obolibrary.org/obo/UBERON_0003867	http://purl.obolibrary.org/obo/PATO_0002087	http://purl.obolibrary.org/obo/UPHENO_0041276
+http://purl.obolibrary.org/obo/UBERON_0003868	http://purl.obolibrary.org/obo/PATO_0002087	http://purl.obolibrary.org/obo/UPHENO_0041277
+http://purl.obolibrary.org/obo/UBERON_0004527	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0041278
+http://purl.obolibrary.org/obo/UBERON_0004406	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0041279
+http://purl.obolibrary.org/obo/UBERON_0003642	http://purl.obolibrary.org/obo/PATO_0002087	http://purl.obolibrary.org/obo/UPHENO_0041280
+http://purl.obolibrary.org/obo/UBERON_0003450	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0041281
+http://purl.obolibrary.org/obo/UBERON_0013749	http://purl.obolibrary.org/obo/PATO_0000944	http://purl.obolibrary.org/obo/UPHENO_0041282
+http://purl.obolibrary.org/obo/UBERON_0002228	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0041055
+http://purl.obolibrary.org/obo/UBERON_0003690	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0041283
+http://purl.obolibrary.org/obo/UBERON_0001037	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0041056
+http://purl.obolibrary.org/obo/UBERON_0002488	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0041058
+http://purl.obolibrary.org/obo/UBERON_0003640	http://purl.obolibrary.org/obo/PATO_0002087	http://purl.obolibrary.org/obo/UPHENO_0041284
+http://purl.obolibrary.org/obo/UBERON_0003641	http://purl.obolibrary.org/obo/PATO_0002087	http://purl.obolibrary.org/obo/UPHENO_0041285
+http://purl.obolibrary.org/obo/UBERON_0004413	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0041286
+http://purl.obolibrary.org/obo/UBERON_0004652	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0041287
+http://purl.obolibrary.org/obo/UBERON_0000056	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0041074
+http://purl.obolibrary.org/obo/UBERON_0001436	http://purl.obolibrary.org/obo/PATO_0002087	http://purl.obolibrary.org/obo/UPHENO_0041288
+http://purl.obolibrary.org/obo/UBERON_0002234	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0041289
+http://purl.obolibrary.org/obo/UBERON_0002113	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0041075
+http://purl.obolibrary.org/obo/UBERON_0002488	http://purl.obolibrary.org/obo/PATO_0001495	http://purl.obolibrary.org/obo/UPHENO_0041290
+http://purl.obolibrary.org/obo/UBERON_0004412	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0041291
+http://purl.obolibrary.org/obo/UBERON_0000964	http://purl.obolibrary.org/obo/PATO_0001848	http://purl.obolibrary.org/obo/UPHENO_0041079
+http://purl.obolibrary.org/obo/UBERON_0012128	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0041080
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0001481	http://purl.obolibrary.org/obo/UPHENO_0041083
+http://purl.obolibrary.org/obo/UBERON_0003863	http://purl.obolibrary.org/obo/PATO_0002087	http://purl.obolibrary.org/obo/UPHENO_0041292
+http://purl.obolibrary.org/obo/UBERON_0003677	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0000165	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0041293
+http://purl.obolibrary.org/obo/UBERON_0003864	http://purl.obolibrary.org/obo/PATO_0002087	http://purl.obolibrary.org/obo/UPHENO_0041294
+http://purl.obolibrary.org/obo/UBERON_0003865	http://purl.obolibrary.org/obo/PATO_0002087	http://purl.obolibrary.org/obo/UPHENO_0041295
+http://purl.obolibrary.org/obo/UBERON_0003862	http://purl.obolibrary.org/obo/PATO_0002087	http://purl.obolibrary.org/obo/UPHENO_0041296
+http://purl.obolibrary.org/obo/UBERON_0003620	http://purl.obolibrary.org/obo/PATO_0002087	http://purl.obolibrary.org/obo/UPHENO_0041297
+http://purl.obolibrary.org/obo/UBERON_0002207	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0041298
+http://purl.obolibrary.org/obo/UBERON_0002347	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0041299
+http://purl.obolibrary.org/obo/UBERON_0003866	http://purl.obolibrary.org/obo/PATO_0002087	http://purl.obolibrary.org/obo/UPHENO_0041300
+http://purl.obolibrary.org/obo/UBERON_0003672	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0041301
+http://purl.obolibrary.org/obo/UBERON_0001467	http://purl.obolibrary.org/obo/PATO_0002143	http://purl.obolibrary.org/obo/UPHENO_0041302
+http://purl.obolibrary.org/obo/UBERON_0000033	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0041100
+http://purl.obolibrary.org/obo/UBERON_0006810	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0041303
+http://purl.obolibrary.org/obo/UBERON_0001437	http://purl.obolibrary.org/obo/PATO_0002142	http://purl.obolibrary.org/obo/UPHENO_0041304
+http://purl.obolibrary.org/obo/UBERON_0001437	http://purl.obolibrary.org/obo/PATO_0002021	http://purl.obolibrary.org/obo/UPHENO_0041305
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0002212	http://purl.obolibrary.org/obo/UPHENO_0041306
+http://purl.obolibrary.org/obo/UBERON_0003639	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0041307
+http://purl.obolibrary.org/obo/UBERON_0004387	http://purl.obolibrary.org/obo/PATO_0000411	http://purl.obolibrary.org/obo/UPHENO_0041308
+http://purl.obolibrary.org/obo/UBERON_0003638	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0041309
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0001594	http://purl.obolibrary.org/obo/UPHENO_0041110
+http://purl.obolibrary.org/obo/UBERON_0003637	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0041310
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0001592	http://purl.obolibrary.org/obo/UPHENO_0041111
+http://purl.obolibrary.org/obo/UBERON_0003636	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0041311
+http://purl.obolibrary.org/obo/UBERON_0004382	http://purl.obolibrary.org/obo/PATO_0000411	http://purl.obolibrary.org/obo/UPHENO_0041312
+http://purl.obolibrary.org/obo/UBERON_0002389	http://purl.obolibrary.org/obo/PATO_0002212	http://purl.obolibrary.org/obo/UPHENO_0041313
+http://purl.obolibrary.org/obo/UBERON_0000388	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0041314
+http://purl.obolibrary.org/obo/UBERON_0006906	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0041315
+http://purl.obolibrary.org/obo/UBERON_0003252	http://purl.obolibrary.org/obo/PATO_0001785	http://purl.obolibrary.org/obo/UPHENO_0041316
+http://purl.obolibrary.org/obo/UBERON_0004385	http://purl.obolibrary.org/obo/PATO_0000411	http://purl.obolibrary.org/obo/UPHENO_0041317
+http://purl.obolibrary.org/obo/UBERON_0003650	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0041318
+http://purl.obolibrary.org/obo/UBERON_0007709	http://purl.obolibrary.org/obo/PATO_0001785	http://purl.obolibrary.org/obo/UPHENO_0041319
+http://purl.obolibrary.org/obo/UBERON_0005928	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0041320
+http://purl.obolibrary.org/obo/UBERON_0003645	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0041321
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0001785	http://purl.obolibrary.org/obo/UPHENO_0041121
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0001786	http://purl.obolibrary.org/obo/UPHENO_0041122
+http://purl.obolibrary.org/obo/UBERON_0004382	http://purl.obolibrary.org/obo/PATO_0000407	http://purl.obolibrary.org/obo/UPHENO_0041322
+http://purl.obolibrary.org/obo/UBERON_0001463	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0041323
+http://purl.obolibrary.org/obo/UBERON_0001105	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0041324
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0001784	http://purl.obolibrary.org/obo/UPHENO_0041123
+http://purl.obolibrary.org/obo/UBERON_0006906	http://purl.obolibrary.org/obo/PATO_0001495	http://purl.obolibrary.org/obo/UPHENO_0041325
+http://purl.obolibrary.org/obo/UBERON_0003868	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0041326
+http://purl.obolibrary.org/obo/UBERON_0003867	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0041327
+http://purl.obolibrary.org/obo/UBERON_0004385	http://purl.obolibrary.org/obo/PATO_0000407	http://purl.obolibrary.org/obo/UPHENO_0041328
+http://purl.obolibrary.org/obo/UBERON_0001075	http://purl.obolibrary.org/obo/PATO_0001891	http://purl.obolibrary.org/obo/UPHENO_0041329
+http://purl.obolibrary.org/obo/UBERON_0001449	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0041330
+http://purl.obolibrary.org/obo/UBERON_0003642	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0041331
+http://purl.obolibrary.org/obo/UBERON_0003641	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0041332
+http://purl.obolibrary.org/obo/UBERON_0001466	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0041333
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+http://purl.obolibrary.org/obo/UBERON_0004314	http://purl.obolibrary.org/obo/PATO_0001875	http://purl.obolibrary.org/obo/UPHENO_0041653
+http://purl.obolibrary.org/obo/UBERON_0004412	http://purl.obolibrary.org/obo/PATO_0000407	http://purl.obolibrary.org/obo/UPHENO_0041654
+http://purl.obolibrary.org/obo/UBERON_0001438	http://purl.obolibrary.org/obo/PATO_0001785	http://purl.obolibrary.org/obo/UPHENO_0041655
+http://purl.obolibrary.org/obo/UBERON_0004316	http://purl.obolibrary.org/obo/PATO_0001875	http://purl.obolibrary.org/obo/UPHENO_0041656
+http://purl.obolibrary.org/obo/UBERON_0001437	http://purl.obolibrary.org/obo/PATO_0001785	http://purl.obolibrary.org/obo/UPHENO_0041657
+http://purl.obolibrary.org/obo/UBERON_0004315	http://purl.obolibrary.org/obo/PATO_0001875	http://purl.obolibrary.org/obo/UPHENO_0041658
+http://purl.obolibrary.org/obo/UBERON_0004313	http://purl.obolibrary.org/obo/PATO_0001875	http://purl.obolibrary.org/obo/UPHENO_0041659
+http://purl.obolibrary.org/obo/UBERON_0001456	http://purl.obolibrary.org/obo/PATO_0001786	http://purl.obolibrary.org/obo/UPHENO_0041242
+http://purl.obolibrary.org/obo/UBERON_0004312	http://purl.obolibrary.org/obo/PATO_0001875	http://purl.obolibrary.org/obo/UPHENO_0041660
+http://purl.obolibrary.org/obo/UBERON_0004311	http://purl.obolibrary.org/obo/PATO_0001875	http://purl.obolibrary.org/obo/UPHENO_0041661
+http://purl.obolibrary.org/obo/UBERON_0001833	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0041662
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0001937	http://purl.obolibrary.org/obo/UPHENO_0041663
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0000967	http://purl.obolibrary.org/obo/UPHENO_0041248
+http://purl.obolibrary.org/obo/UBERON_0000995	http://purl.obolibrary.org/obo/PATO_0002161	http://purl.obolibrary.org/obo/UPHENO_0041664
+http://purl.obolibrary.org/obo/UBERON_0002234	http://purl.obolibrary.org/obo/PATO_0000406	http://purl.obolibrary.org/obo/UPHENO_0041665
+http://purl.obolibrary.org/obo/UBERON_0002495	http://purl.obolibrary.org/obo/PATO_0001876	http://purl.obolibrary.org/obo/UPHENO_0041666
+http://purl.obolibrary.org/obo/UBERON_0000056	http://purl.obolibrary.org/obo/PATO_0000403	http://purl.obolibrary.org/obo/UPHENO_0041249
+http://purl.obolibrary.org/obo/UBERON_0001711	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0041667
+http://purl.obolibrary.org/obo/UBERON_0002374	http://purl.obolibrary.org/obo/PATO_0001873	http://purl.obolibrary.org/obo/UPHENO_0041668
diff --git a/src/curation/upheno-fillers/hp/abnormalShapeOfAnatomicalEntityByShapeTypeInLocation.tsv b/src/curation/upheno-fillers/hp/abnormalShapeOfAnatomicalEntityByShapeTypeInLocation.tsv
new file mode 100644
index 00000000..ee6fa263
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormalShapeOfAnatomicalEntityByShapeTypeInLocation.tsv
@@ -0,0 +1,357 @@
+anatomical_entity	location	shape	defined_class
+http://purl.obolibrary.org/obo/UBERON_0004387	http://purl.obolibrary.org/obo/UBERON_0004330	http://purl.obolibrary.org/obo/PATO_0001875	http://purl.obolibrary.org/obo/UPHENO_0082045
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0004320	http://purl.obolibrary.org/obo/PATO_0001875	http://purl.obolibrary.org/obo/UPHENO_0082046
+http://purl.obolibrary.org/obo/UBERON_0004387	http://purl.obolibrary.org/obo/UBERON_0004331	http://purl.obolibrary.org/obo/PATO_0001875	http://purl.obolibrary.org/obo/UPHENO_0082047
+http://purl.obolibrary.org/obo/UBERON_0004387	http://purl.obolibrary.org/obo/UBERON_0004312	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0082048
+http://purl.obolibrary.org/obo/UBERON_0004387	http://purl.obolibrary.org/obo/UBERON_0004313	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0082049
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0004313	http://purl.obolibrary.org/obo/PATO_0002021	http://purl.obolibrary.org/obo/UPHENO_0082050
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0004316	http://purl.obolibrary.org/obo/PATO_0002142	http://purl.obolibrary.org/obo/UPHENO_0082051
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0004316	http://purl.obolibrary.org/obo/PATO_0002021	http://purl.obolibrary.org/obo/UPHENO_0082052
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0004311	http://purl.obolibrary.org/obo/PATO_0002142	http://purl.obolibrary.org/obo/UPHENO_0082053
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0004311	http://purl.obolibrary.org/obo/PATO_0002021	http://purl.obolibrary.org/obo/UPHENO_0082054
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0004312	http://purl.obolibrary.org/obo/PATO_0002142	http://purl.obolibrary.org/obo/UPHENO_0082055
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0004312	http://purl.obolibrary.org/obo/PATO_0002021	http://purl.obolibrary.org/obo/UPHENO_0082056
+http://purl.obolibrary.org/obo/UBERON_0001437	http://purl.obolibrary.org/obo/UBERON_0010708	http://purl.obolibrary.org/obo/PATO_0000411	http://purl.obolibrary.org/obo/UPHENO_0082059
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0004314	http://purl.obolibrary.org/obo/PATO_0002142	http://purl.obolibrary.org/obo/UPHENO_0082060
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0004314	http://purl.obolibrary.org/obo/PATO_0002021	http://purl.obolibrary.org/obo/UPHENO_0082061
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0004317	http://purl.obolibrary.org/obo/PATO_0002142	http://purl.obolibrary.org/obo/UPHENO_0082062
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0004317	http://purl.obolibrary.org/obo/PATO_0002021	http://purl.obolibrary.org/obo/UPHENO_0082063
+http://purl.obolibrary.org/obo/UBERON_0004387	http://purl.obolibrary.org/obo/UBERON_0004323	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0082064
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0004315	http://purl.obolibrary.org/obo/PATO_0002142	http://purl.obolibrary.org/obo/UPHENO_0082065
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0004315	http://purl.obolibrary.org/obo/PATO_0002021	http://purl.obolibrary.org/obo/UPHENO_0082066
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0004321	http://purl.obolibrary.org/obo/PATO_0002142	http://purl.obolibrary.org/obo/UPHENO_0082067
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0004321	http://purl.obolibrary.org/obo/PATO_0002021	http://purl.obolibrary.org/obo/UPHENO_0082068
+http://purl.obolibrary.org/obo/UBERON_0004387	http://purl.obolibrary.org/obo/UBERON_0004311	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0082069
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0004324	http://purl.obolibrary.org/obo/PATO_0002142	http://purl.obolibrary.org/obo/UPHENO_0082070
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0004324	http://purl.obolibrary.org/obo/PATO_0002021	http://purl.obolibrary.org/obo/UPHENO_0082071
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0004327	http://purl.obolibrary.org/obo/PATO_0002142	http://purl.obolibrary.org/obo/UPHENO_0082072
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0004327	http://purl.obolibrary.org/obo/PATO_0002021	http://purl.obolibrary.org/obo/UPHENO_0082073
+http://purl.obolibrary.org/obo/UBERON_0004387	http://purl.obolibrary.org/obo/UBERON_0004314	http://purl.obolibrary.org/obo/PATO_0001875	http://purl.obolibrary.org/obo/UPHENO_0082074
+http://purl.obolibrary.org/obo/UBERON_0001437	http://purl.obolibrary.org/obo/UBERON_0004334	http://purl.obolibrary.org/obo/PATO_0001875	http://purl.obolibrary.org/obo/UPHENO_0082075
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0004322	http://purl.obolibrary.org/obo/PATO_0002142	http://purl.obolibrary.org/obo/UPHENO_0082076
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0004322	http://purl.obolibrary.org/obo/PATO_0002021	http://purl.obolibrary.org/obo/UPHENO_0082077
+http://purl.obolibrary.org/obo/UBERON_0004387	http://purl.obolibrary.org/obo/UBERON_0004314	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0082078
+http://purl.obolibrary.org/obo/UBERON_0004387	http://purl.obolibrary.org/obo/UBERON_0004329	http://purl.obolibrary.org/obo/PATO_0002142	http://purl.obolibrary.org/obo/UPHENO_0082079
+http://purl.obolibrary.org/obo/UBERON_0004387	http://purl.obolibrary.org/obo/UBERON_0004329	http://purl.obolibrary.org/obo/PATO_0002021	http://purl.obolibrary.org/obo/UPHENO_0082080
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0004323	http://purl.obolibrary.org/obo/PATO_0002021	http://purl.obolibrary.org/obo/UPHENO_0082081
+http://purl.obolibrary.org/obo/UBERON_0001437	http://purl.obolibrary.org/obo/UBERON_0004334	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0082082
+http://purl.obolibrary.org/obo/UBERON_0004387	http://purl.obolibrary.org/obo/UBERON_0004311	http://purl.obolibrary.org/obo/PATO_0001875	http://purl.obolibrary.org/obo/UPHENO_0082083
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0004318	http://purl.obolibrary.org/obo/PATO_0002142	http://purl.obolibrary.org/obo/UPHENO_0082084
+http://purl.obolibrary.org/obo/UBERON_0001437	http://purl.obolibrary.org/obo/UBERON_0004335	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0082085
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0004318	http://purl.obolibrary.org/obo/PATO_0002021	http://purl.obolibrary.org/obo/UPHENO_0082086
+http://purl.obolibrary.org/obo/UBERON_0004387	http://purl.obolibrary.org/obo/UBERON_0004312	http://purl.obolibrary.org/obo/PATO_0001875	http://purl.obolibrary.org/obo/UPHENO_0082087
+http://purl.obolibrary.org/obo/UBERON_0001437	http://purl.obolibrary.org/obo/UBERON_0004332	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0082088
+http://purl.obolibrary.org/obo/UBERON_0004387	http://purl.obolibrary.org/obo/UBERON_0004313	http://purl.obolibrary.org/obo/PATO_0001875	http://purl.obolibrary.org/obo/UPHENO_0082089
+http://purl.obolibrary.org/obo/UBERON_0001437	http://purl.obolibrary.org/obo/UBERON_0004333	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0082090
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0004319	http://purl.obolibrary.org/obo/PATO_0002142	http://purl.obolibrary.org/obo/UPHENO_0082091
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0004319	http://purl.obolibrary.org/obo/PATO_0002021	http://purl.obolibrary.org/obo/UPHENO_0082092
+http://purl.obolibrary.org/obo/UBERON_0001437	http://purl.obolibrary.org/obo/UBERON_0004336	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0082093
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0004320	http://purl.obolibrary.org/obo/PATO_0002142	http://purl.obolibrary.org/obo/UPHENO_0082094
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0004320	http://purl.obolibrary.org/obo/PATO_0002021	http://purl.obolibrary.org/obo/UPHENO_0082095
+http://purl.obolibrary.org/obo/UBERON_0004387	http://purl.obolibrary.org/obo/UBERON_0004331	http://purl.obolibrary.org/obo/PATO_0002142	http://purl.obolibrary.org/obo/UPHENO_0082096
+http://purl.obolibrary.org/obo/UBERON_0004387	http://purl.obolibrary.org/obo/UBERON_0004331	http://purl.obolibrary.org/obo/PATO_0002021	http://purl.obolibrary.org/obo/UPHENO_0082097
+http://purl.obolibrary.org/obo/UBERON_0004387	http://purl.obolibrary.org/obo/UBERON_0004330	http://purl.obolibrary.org/obo/PATO_0002021	http://purl.obolibrary.org/obo/UPHENO_0082098
+http://purl.obolibrary.org/obo/UBERON_0004387	http://purl.obolibrary.org/obo/UBERON_0004337	http://purl.obolibrary.org/obo/PATO_0002142	http://purl.obolibrary.org/obo/UPHENO_0082099
+http://purl.obolibrary.org/obo/UBERON_0004387	http://purl.obolibrary.org/obo/UBERON_0004337	http://purl.obolibrary.org/obo/PATO_0002021	http://purl.obolibrary.org/obo/UPHENO_0082100
+http://purl.obolibrary.org/obo/UBERON_0001437	http://purl.obolibrary.org/obo/UBERON_0004336	http://purl.obolibrary.org/obo/PATO_0001875	http://purl.obolibrary.org/obo/UPHENO_0082101
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0004325	http://purl.obolibrary.org/obo/PATO_0002142	http://purl.obolibrary.org/obo/UPHENO_0082102
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0004325	http://purl.obolibrary.org/obo/PATO_0002021	http://purl.obolibrary.org/obo/UPHENO_0082103
+http://purl.obolibrary.org/obo/UBERON_0001437	http://purl.obolibrary.org/obo/UBERON_0004332	http://purl.obolibrary.org/obo/PATO_0001875	http://purl.obolibrary.org/obo/UPHENO_0082104
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0004328	http://purl.obolibrary.org/obo/PATO_0002142	http://purl.obolibrary.org/obo/UPHENO_0082105
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0004328	http://purl.obolibrary.org/obo/PATO_0002021	http://purl.obolibrary.org/obo/UPHENO_0082106
+http://purl.obolibrary.org/obo/UBERON_0001437	http://purl.obolibrary.org/obo/UBERON_0004335	http://purl.obolibrary.org/obo/PATO_0001875	http://purl.obolibrary.org/obo/UPHENO_0082107
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0004326	http://purl.obolibrary.org/obo/PATO_0002142	http://purl.obolibrary.org/obo/UPHENO_0082108
+http://purl.obolibrary.org/obo/UBERON_0004387	http://purl.obolibrary.org/obo/UBERON_0004338	http://purl.obolibrary.org/obo/PATO_0002142	http://purl.obolibrary.org/obo/UPHENO_0082109
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0004326	http://purl.obolibrary.org/obo/PATO_0002021	http://purl.obolibrary.org/obo/UPHENO_0082110
+http://purl.obolibrary.org/obo/UBERON_0004387	http://purl.obolibrary.org/obo/UBERON_0004338	http://purl.obolibrary.org/obo/PATO_0002021	http://purl.obolibrary.org/obo/UPHENO_0082111
+http://purl.obolibrary.org/obo/UBERON_0001437	http://purl.obolibrary.org/obo/UBERON_0004333	http://purl.obolibrary.org/obo/PATO_0001875	http://purl.obolibrary.org/obo/UPHENO_0082112
+http://purl.obolibrary.org/obo/UBERON_0004387	http://purl.obolibrary.org/obo/UBERON_0004321	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0082113
+http://purl.obolibrary.org/obo/UBERON_0004387	http://purl.obolibrary.org/obo/UBERON_0004322	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0082114
+http://purl.obolibrary.org/obo/UBERON_0004387	http://purl.obolibrary.org/obo/UBERON_0004328	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0082115
+http://purl.obolibrary.org/obo/UBERON_0004387	http://purl.obolibrary.org/obo/UBERON_0004328	http://purl.obolibrary.org/obo/PATO_0001875	http://purl.obolibrary.org/obo/UPHENO_0082116
+http://purl.obolibrary.org/obo/UBERON_0004387	http://purl.obolibrary.org/obo/UBERON_0004321	http://purl.obolibrary.org/obo/PATO_0001875	http://purl.obolibrary.org/obo/UPHENO_0082117
+http://purl.obolibrary.org/obo/UBERON_0004387	http://purl.obolibrary.org/obo/UBERON_0004322	http://purl.obolibrary.org/obo/PATO_0001875	http://purl.obolibrary.org/obo/UPHENO_0082118
+http://purl.obolibrary.org/obo/UBERON_0004387	http://purl.obolibrary.org/obo/UBERON_0004323	http://purl.obolibrary.org/obo/PATO_0001875	http://purl.obolibrary.org/obo/UPHENO_0082120
+http://purl.obolibrary.org/obo/UBERON_0004387	http://purl.obolibrary.org/obo/UBERON_0004320	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0082121
+http://purl.obolibrary.org/obo/UBERON_0004387	http://purl.obolibrary.org/obo/UBERON_0004320	http://purl.obolibrary.org/obo/PATO_0001875	http://purl.obolibrary.org/obo/UPHENO_0082123
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0003640	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0082124
+http://purl.obolibrary.org/obo/UBERON_0004387	http://purl.obolibrary.org/obo/UBERON_0004313	http://purl.obolibrary.org/obo/PATO_0002021	http://purl.obolibrary.org/obo/UPHENO_0082125
+http://purl.obolibrary.org/obo/UBERON_0004387	http://purl.obolibrary.org/obo/UBERON_0004312	http://purl.obolibrary.org/obo/PATO_0002142	http://purl.obolibrary.org/obo/UPHENO_0082126
+http://purl.obolibrary.org/obo/UBERON_0004387	http://purl.obolibrary.org/obo/UBERON_0004312	http://purl.obolibrary.org/obo/PATO_0002021	http://purl.obolibrary.org/obo/UPHENO_0082127
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0001463	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0082128
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0003637	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0082130
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+http://purl.obolibrary.org/obo/UBERON_0001437	http://purl.obolibrary.org/obo/UBERON_0004315	http://purl.obolibrary.org/obo/PATO_0001875	http://purl.obolibrary.org/obo/UPHENO_0082333
+http://purl.obolibrary.org/obo/UBERON_0004387	http://purl.obolibrary.org/obo/UBERON_0004311	http://purl.obolibrary.org/obo/PATO_0002142	http://purl.obolibrary.org/obo/UPHENO_0082334
+http://purl.obolibrary.org/obo/UBERON_0004387	http://purl.obolibrary.org/obo/UBERON_0004311	http://purl.obolibrary.org/obo/PATO_0002021	http://purl.obolibrary.org/obo/UPHENO_0082335
+http://purl.obolibrary.org/obo/UBERON_0001437	http://purl.obolibrary.org/obo/UBERON_0004316	http://purl.obolibrary.org/obo/PATO_0001875	http://purl.obolibrary.org/obo/UPHENO_0082336
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0001465	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0082337
+http://purl.obolibrary.org/obo/UBERON_0001437	http://purl.obolibrary.org/obo/UBERON_0004318	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0082338
+http://purl.obolibrary.org/obo/UBERON_0001437	http://purl.obolibrary.org/obo/UBERON_0004319	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0082339
+http://purl.obolibrary.org/obo/UBERON_0004387	http://purl.obolibrary.org/obo/UBERON_0004323	http://purl.obolibrary.org/obo/PATO_0002021	http://purl.obolibrary.org/obo/UPHENO_0082340
+http://purl.obolibrary.org/obo/UBERON_0001437	http://purl.obolibrary.org/obo/UBERON_0004318	http://purl.obolibrary.org/obo/PATO_0001875	http://purl.obolibrary.org/obo/UPHENO_0082341
+http://purl.obolibrary.org/obo/UBERON_0001437	http://purl.obolibrary.org/obo/UBERON_0004319	http://purl.obolibrary.org/obo/PATO_0001875	http://purl.obolibrary.org/obo/UPHENO_0082343
+http://purl.obolibrary.org/obo/UBERON_0001437	http://purl.obolibrary.org/obo/UBERON_0004324	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0082344
+http://purl.obolibrary.org/obo/UBERON_0001437	http://purl.obolibrary.org/obo/UBERON_0004327	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0082345
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0003640	http://purl.obolibrary.org/obo/PATO_0001875	http://purl.obolibrary.org/obo/UPHENO_0082346
+http://purl.obolibrary.org/obo/UBERON_0001437	http://purl.obolibrary.org/obo/UBERON_0004325	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0082347
+http://purl.obolibrary.org/obo/UBERON_0001437	http://purl.obolibrary.org/obo/UBERON_0004326	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0082348
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0001463	http://purl.obolibrary.org/obo/PATO_0001875	http://purl.obolibrary.org/obo/UPHENO_0082351
+http://purl.obolibrary.org/obo/UBERON_0004387	http://purl.obolibrary.org/obo/UBERON_0004320	http://purl.obolibrary.org/obo/PATO_0002142	http://purl.obolibrary.org/obo/UPHENO_0082352
+http://purl.obolibrary.org/obo/UBERON_0004387	http://purl.obolibrary.org/obo/UBERON_0004320	http://purl.obolibrary.org/obo/PATO_0002021	http://purl.obolibrary.org/obo/UPHENO_0082353
+http://purl.obolibrary.org/obo/UBERON_0001437	http://purl.obolibrary.org/obo/UBERON_0004325	http://purl.obolibrary.org/obo/PATO_0001875	http://purl.obolibrary.org/obo/UPHENO_0082354
+http://purl.obolibrary.org/obo/UBERON_0000009	http://purl.obolibrary.org/obo/UBERON_0001833	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0082355
+http://purl.obolibrary.org/obo/UBERON_0001437	http://purl.obolibrary.org/obo/UBERON_0004326	http://purl.obolibrary.org/obo/PATO_0001875	http://purl.obolibrary.org/obo/UPHENO_0082357
+http://purl.obolibrary.org/obo/UBERON_0004387	http://purl.obolibrary.org/obo/UBERON_0004322	http://purl.obolibrary.org/obo/PATO_0002142	http://purl.obolibrary.org/obo/UPHENO_0082358
+http://purl.obolibrary.org/obo/UBERON_0004387	http://purl.obolibrary.org/obo/UBERON_0004322	http://purl.obolibrary.org/obo/PATO_0002021	http://purl.obolibrary.org/obo/UPHENO_0082359
+http://purl.obolibrary.org/obo/UBERON_0001437	http://purl.obolibrary.org/obo/UBERON_0010708	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0082360
+http://purl.obolibrary.org/obo/UBERON_0004387	http://purl.obolibrary.org/obo/UBERON_0004321	http://purl.obolibrary.org/obo/PATO_0002142	http://purl.obolibrary.org/obo/UPHENO_0082361
+http://purl.obolibrary.org/obo/UBERON_0004387	http://purl.obolibrary.org/obo/UBERON_0004321	http://purl.obolibrary.org/obo/PATO_0002021	http://purl.obolibrary.org/obo/UPHENO_0082362
+http://purl.obolibrary.org/obo/UBERON_0001437	http://purl.obolibrary.org/obo/UBERON_0004324	http://purl.obolibrary.org/obo/PATO_0001875	http://purl.obolibrary.org/obo/UPHENO_0082363
+http://purl.obolibrary.org/obo/UBERON_0004387	http://purl.obolibrary.org/obo/UBERON_0004328	http://purl.obolibrary.org/obo/PATO_0002142	http://purl.obolibrary.org/obo/UPHENO_0082364
+http://purl.obolibrary.org/obo/UBERON_0004387	http://purl.obolibrary.org/obo/UBERON_0004328	http://purl.obolibrary.org/obo/PATO_0002021	http://purl.obolibrary.org/obo/UPHENO_0082365
+http://purl.obolibrary.org/obo/UBERON_0001437	http://purl.obolibrary.org/obo/UBERON_0004327	http://purl.obolibrary.org/obo/PATO_0001875	http://purl.obolibrary.org/obo/UPHENO_0082366
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0003865	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0082367
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0003620	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0082368
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0001833	http://purl.obolibrary.org/obo/PATO_0001786	http://purl.obolibrary.org/obo/UPHENO_0082369
+http://purl.obolibrary.org/obo/UBERON_0001437	http://purl.obolibrary.org/obo/UBERON_0004317	http://purl.obolibrary.org/obo/PATO_0002142	http://purl.obolibrary.org/obo/UPHENO_0082370
+http://purl.obolibrary.org/obo/UBERON_0001437	http://purl.obolibrary.org/obo/UBERON_0004317	http://purl.obolibrary.org/obo/PATO_0002021	http://purl.obolibrary.org/obo/UPHENO_0082371
+http://purl.obolibrary.org/obo/UBERON_0001437	http://purl.obolibrary.org/obo/UBERON_0004315	http://purl.obolibrary.org/obo/PATO_0002142	http://purl.obolibrary.org/obo/UPHENO_0082372
+http://purl.obolibrary.org/obo/UBERON_0001437	http://purl.obolibrary.org/obo/UBERON_0004315	http://purl.obolibrary.org/obo/PATO_0002021	http://purl.obolibrary.org/obo/UPHENO_0082373
+http://purl.obolibrary.org/obo/UBERON_0001437	http://purl.obolibrary.org/obo/UBERON_0004316	http://purl.obolibrary.org/obo/PATO_0002142	http://purl.obolibrary.org/obo/UPHENO_0082374
+http://purl.obolibrary.org/obo/UBERON_0004387	http://purl.obolibrary.org/obo/UBERON_0003638	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0082375
+http://purl.obolibrary.org/obo/UBERON_0001437	http://purl.obolibrary.org/obo/UBERON_0004316	http://purl.obolibrary.org/obo/PATO_0002021	http://purl.obolibrary.org/obo/UPHENO_0082376
+http://purl.obolibrary.org/obo/UBERON_0004387	http://purl.obolibrary.org/obo/UBERON_0003639	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0082377
+http://purl.obolibrary.org/obo/UBERON_0004387	http://purl.obolibrary.org/obo/UBERON_0003637	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0082378
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0003622	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0082380
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0003864	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0082381
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0003624	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0082382
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0003634	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0082383
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0001463	http://purl.obolibrary.org/obo/PATO_0002142	http://purl.obolibrary.org/obo/UPHENO_0082384
+http://purl.obolibrary.org/obo/UBERON_0004387	http://purl.obolibrary.org/obo/UBERON_0001463	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0082385
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0003640	http://purl.obolibrary.org/obo/PATO_0002142	http://purl.obolibrary.org/obo/UPHENO_0082386
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0003640	http://purl.obolibrary.org/obo/PATO_0002021	http://purl.obolibrary.org/obo/UPHENO_0082387
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0003622	http://purl.obolibrary.org/obo/PATO_0001875	http://purl.obolibrary.org/obo/UPHENO_0082388
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0003864	http://purl.obolibrary.org/obo/PATO_0001875	http://purl.obolibrary.org/obo/UPHENO_0082389
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0003637	http://purl.obolibrary.org/obo/PATO_0002142	http://purl.obolibrary.org/obo/UPHENO_0082390
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0003625	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0082391
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0003637	http://purl.obolibrary.org/obo/PATO_0002021	http://purl.obolibrary.org/obo/UPHENO_0082392
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0003865	http://purl.obolibrary.org/obo/PATO_0001875	http://purl.obolibrary.org/obo/UPHENO_0082393
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0001449	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0082394
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0001465	http://purl.obolibrary.org/obo/PATO_0000407	http://purl.obolibrary.org/obo/UPHENO_0082395
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0010708	http://purl.obolibrary.org/obo/PATO_0000411	http://purl.obolibrary.org/obo/UPHENO_0082396
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0003638	http://purl.obolibrary.org/obo/PATO_0002021	http://purl.obolibrary.org/obo/UPHENO_0082397
+http://purl.obolibrary.org/obo/UBERON_0001437	http://purl.obolibrary.org/obo/UBERON_0004325	http://purl.obolibrary.org/obo/PATO_0002142	http://purl.obolibrary.org/obo/UPHENO_0082398
+http://purl.obolibrary.org/obo/UBERON_0001437	http://purl.obolibrary.org/obo/UBERON_0004325	http://purl.obolibrary.org/obo/PATO_0002021	http://purl.obolibrary.org/obo/UPHENO_0082399
+http://purl.obolibrary.org/obo/UBERON_0004387	http://purl.obolibrary.org/obo/UBERON_0003639	http://purl.obolibrary.org/obo/PATO_0001875	http://purl.obolibrary.org/obo/UPHENO_0082400
+http://purl.obolibrary.org/obo/UBERON_0001437	http://purl.obolibrary.org/obo/UBERON_0004326	http://purl.obolibrary.org/obo/PATO_0002142	http://purl.obolibrary.org/obo/UPHENO_0082401
+http://purl.obolibrary.org/obo/UBERON_0001437	http://purl.obolibrary.org/obo/UBERON_0004326	http://purl.obolibrary.org/obo/PATO_0002021	http://purl.obolibrary.org/obo/UPHENO_0082402
+http://purl.obolibrary.org/obo/UBERON_0004387	http://purl.obolibrary.org/obo/UBERON_0003638	http://purl.obolibrary.org/obo/PATO_0001875	http://purl.obolibrary.org/obo/UPHENO_0082403
+http://purl.obolibrary.org/obo/UBERON_0001437	http://purl.obolibrary.org/obo/UBERON_0004324	http://purl.obolibrary.org/obo/PATO_0002142	http://purl.obolibrary.org/obo/UPHENO_0082404
+http://purl.obolibrary.org/obo/UBERON_0001437	http://purl.obolibrary.org/obo/UBERON_0004324	http://purl.obolibrary.org/obo/PATO_0002021	http://purl.obolibrary.org/obo/UPHENO_0082405
+http://purl.obolibrary.org/obo/UBERON_0001437	http://purl.obolibrary.org/obo/UBERON_0004327	http://purl.obolibrary.org/obo/PATO_0002142	http://purl.obolibrary.org/obo/UPHENO_0082406
+http://purl.obolibrary.org/obo/UBERON_0001437	http://purl.obolibrary.org/obo/UBERON_0004327	http://purl.obolibrary.org/obo/PATO_0002021	http://purl.obolibrary.org/obo/UPHENO_0082407
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0001449	http://purl.obolibrary.org/obo/PATO_0001875	http://purl.obolibrary.org/obo/UPHENO_0082408
+http://purl.obolibrary.org/obo/UBERON_0001437	http://purl.obolibrary.org/obo/UBERON_0004318	http://purl.obolibrary.org/obo/PATO_0002142	http://purl.obolibrary.org/obo/UPHENO_0082409
+http://purl.obolibrary.org/obo/UBERON_0001437	http://purl.obolibrary.org/obo/UBERON_0004318	http://purl.obolibrary.org/obo/PATO_0002021	http://purl.obolibrary.org/obo/UPHENO_0082410
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0003633	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0082411
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0003632	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0082412
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0003635	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0082413
+http://purl.obolibrary.org/obo/UBERON_0001437	http://purl.obolibrary.org/obo/UBERON_0004319	http://purl.obolibrary.org/obo/PATO_0002142	http://purl.obolibrary.org/obo/UPHENO_0082414
+http://purl.obolibrary.org/obo/UBERON_0001437	http://purl.obolibrary.org/obo/UBERON_0004319	http://purl.obolibrary.org/obo/PATO_0002021	http://purl.obolibrary.org/obo/UPHENO_0082415
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0002234	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0082416
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0003632	http://purl.obolibrary.org/obo/PATO_0001875	http://purl.obolibrary.org/obo/UPHENO_0082417
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0003635	http://purl.obolibrary.org/obo/PATO_0001875	http://purl.obolibrary.org/obo/UPHENO_0082418
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0003633	http://purl.obolibrary.org/obo/PATO_0001875	http://purl.obolibrary.org/obo/UPHENO_0082419
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0003634	http://purl.obolibrary.org/obo/PATO_0001875	http://purl.obolibrary.org/obo/UPHENO_0082420
+http://purl.obolibrary.org/obo/UBERON_0004387	http://purl.obolibrary.org/obo/UBERON_0001463	http://purl.obolibrary.org/obo/PATO_0001875	http://purl.obolibrary.org/obo/UPHENO_0082421
+http://purl.obolibrary.org/obo/UBERON_0004387	http://purl.obolibrary.org/obo/UBERON_0003637	http://purl.obolibrary.org/obo/PATO_0001875	http://purl.obolibrary.org/obo/UPHENO_0082423
diff --git a/src/curation/upheno-fillers/hp/abnormalShapeOfPhysicalEntity.tsv b/src/curation/upheno-fillers/hp/abnormalShapeOfPhysicalEntity.tsv
new file mode 100644
index 00000000..e5a06a31
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormalShapeOfPhysicalEntity.tsv
@@ -0,0 +1,11 @@
+entity	defined_class
+http://purl.obolibrary.org/obo/GO_0005739	http://purl.obolibrary.org/obo/UPHENO_0005993
+http://purl.obolibrary.org/obo/UBERON_0001870	http://purl.obolibrary.org/obo/UPHENO_0005994
+http://purl.obolibrary.org/obo/UBERON_0001819	http://purl.obolibrary.org/obo/UPHENO_0005995
+http://purl.obolibrary.org/obo/BFO_0000002	http://purl.obolibrary.org/obo/UPHENO_0080300
+http://purl.obolibrary.org/obo/UBERON_0001676	http://purl.obolibrary.org/obo/UPHENO_0005996
+http://purl.obolibrary.org/obo/UBERON_0000965	http://purl.obolibrary.org/obo/UPHENO_0005997
+http://purl.obolibrary.org/obo/CL_0000233	http://purl.obolibrary.org/obo/UPHENO_0005985
+http://purl.obolibrary.org/obo/UBERON_0000964	http://purl.obolibrary.org/obo/UPHENO_0005998
+http://purl.obolibrary.org/obo/UBERON_0001691	http://purl.obolibrary.org/obo/UPHENO_0005986
+http://purl.obolibrary.org/obo/CL_0000232	http://purl.obolibrary.org/obo/UPHENO_0005987
diff --git a/src/curation/upheno-fillers/hp/abnormalSizeOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/hp/abnormalSizeOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..b8a70747
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormalSizeOfAnatomicalEntity.tsv
@@ -0,0 +1,15 @@
+entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0000165	http://purl.obolibrary.org/obo/UPHENO_0075216
+http://purl.obolibrary.org/obo/UBERON_0001732	http://purl.obolibrary.org/obo/UPHENO_0075217
+http://purl.obolibrary.org/obo/UBERON_0003677	http://purl.obolibrary.org/obo/UPHENO_0075218
+http://purl.obolibrary.org/obo/CL_0008002	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002411	http://purl.obolibrary.org/obo/UPHENO_0075153
+http://purl.obolibrary.org/obo/UBERON_0003129	http://purl.obolibrary.org/obo/UPHENO_0075220
+http://purl.obolibrary.org/obo/CL_0000232	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0075195
+http://purl.obolibrary.org/obo/UBERON_0001819	http://purl.obolibrary.org/obo/UPHENO_0075198
+http://purl.obolibrary.org/obo/UBERON_0010230	http://purl.obolibrary.org/obo/UPHENO_0075219
+http://purl.obolibrary.org/obo/UBERON_0004703	http://purl.obolibrary.org/obo/UPHENO_0075221
+http://purl.obolibrary.org/obo/UBERON_0001987	http://purl.obolibrary.org/obo/UPHENO_0075215
+http://purl.obolibrary.org/obo/UBERON_0000007	http://purl.obolibrary.org/obo/UPHENO_0075203
+http://purl.obolibrary.org/obo/UBERON_0000964	http://purl.obolibrary.org/obo/UPHENO_0075222
diff --git a/src/curation/upheno-fillers/hp/abnormalSpatialPatternOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/hp/abnormalSpatialPatternOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..6e300a87
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormalSpatialPatternOfAnatomicalEntity.tsv
@@ -0,0 +1,3 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0080369
+http://purl.obolibrary.org/obo/UBERON_0001037	http://purl.obolibrary.org/obo/UPHENO_0080375
diff --git a/src/curation/upheno-fillers/hp/abnormalThicknessOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/hp/abnormalThicknessOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..68d00732
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormalThicknessOfAnatomicalEntity.tsv
@@ -0,0 +1,3 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0000964	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/hp/abnormalWeightOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/hp/abnormalWeightOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..8371d219
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormalWeightOfAnatomicalEntity.tsv
@@ -0,0 +1,3 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0010763
+http://purl.obolibrary.org/obo/UBERON_0000468	http://purl.obolibrary.org/obo/UPHENO_0010795
diff --git a/src/curation/upheno-fillers/hp/abnormallyArchedAnatomicalEntity.tsv b/src/curation/upheno-fillers/hp/abnormallyArchedAnatomicalEntity.tsv
new file mode 100644
index 00000000..78823515
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormallyArchedAnatomicalEntity.tsv
@@ -0,0 +1,3 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0010163	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/hp/abnormallyArrestedBiologicalProcessInLocation.tsv b/src/curation/upheno-fillers/hp/abnormallyArrestedBiologicalProcessInLocation.tsv
new file mode 100644
index 00000000..957ee273
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormallyArrestedBiologicalProcessInLocation.tsv
@@ -0,0 +1,3 @@
+biological_process	location	defined_class
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0002336	http://purl.obolibrary.org/obo/UPHENO_0067135
+http://purl.obolibrary.org/obo/GO_0048513	http://purl.obolibrary.org/obo/UBERON_0002336	http://purl.obolibrary.org/obo/UPHENO_0067139
diff --git a/src/curation/upheno-fillers/hp/abnormallyAsymmetricalAnatomicalEntity.tsv b/src/curation/upheno-fillers/hp/abnormallyAsymmetricalAnatomicalEntity.tsv
new file mode 100644
index 00000000..2535cbff
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormallyAsymmetricalAnatomicalEntity.tsv
@@ -0,0 +1,15 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0084729
+http://purl.obolibrary.org/obo/UBERON_0007830	http://purl.obolibrary.org/obo/UPHENO_0084737
+http://purl.obolibrary.org/obo/UBERON_0001690	http://purl.obolibrary.org/obo/UPHENO_0084738
+http://purl.obolibrary.org/obo/UBERON_0000310	http://purl.obolibrary.org/obo/UPHENO_0084739
+http://purl.obolibrary.org/obo/UBERON_0001443	http://purl.obolibrary.org/obo/UPHENO_0084740
+http://purl.obolibrary.org/obo/UBERON_0003129	http://purl.obolibrary.org/obo/UPHENO_0084741
+http://purl.obolibrary.org/obo/UBERON_0001456	http://purl.obolibrary.org/obo/UPHENO_0084734
+http://purl.obolibrary.org/obo/UBERON_0001684	http://purl.obolibrary.org/obo/UPHENO_0084742
+http://purl.obolibrary.org/obo/UBERON_0000165	http://purl.obolibrary.org/obo/UPHENO_0084743
+http://purl.obolibrary.org/obo/UBERON_0002387	http://purl.obolibrary.org/obo/UPHENO_0084744
+http://purl.obolibrary.org/obo/UBERON_0005928	http://purl.obolibrary.org/obo/UPHENO_0084745
+http://purl.obolibrary.org/obo/UBERON_0000964	http://purl.obolibrary.org/obo/UPHENO_0084746
+http://purl.obolibrary.org/obo/UBERON_0036014	http://purl.obolibrary.org/obo/UPHENO_0084747
+http://purl.obolibrary.org/obo/UBERON_0011156	http://purl.obolibrary.org/obo/UPHENO_0084748
diff --git a/src/curation/upheno-fillers/hp/abnormallyBentAnatomicalEntity.tsv b/src/curation/upheno-fillers/hp/abnormallyBentAnatomicalEntity.tsv
new file mode 100644
index 00000000..12f4abe4
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormallyBentAnatomicalEntity.tsv
@@ -0,0 +1,3 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0074399
+http://purl.obolibrary.org/obo/UBERON_0000004	http://purl.obolibrary.org/obo/UPHENO_0074421
diff --git a/src/curation/upheno-fillers/hp/abnormallyCurledAnatomicalEntity.tsv b/src/curation/upheno-fillers/hp/abnormallyCurledAnatomicalEntity.tsv
new file mode 100644
index 00000000..76483315
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormallyCurledAnatomicalEntity.tsv
@@ -0,0 +1,4 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001702	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001037	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/hp/abnormallyCurvedAnatomicalEntityByOrientation.tsv b/src/curation/upheno-fillers/hp/abnormallyCurvedAnatomicalEntityByOrientation.tsv
new file mode 100644
index 00000000..a60f65c1
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormallyCurvedAnatomicalEntityByOrientation.tsv
@@ -0,0 +1,45 @@
+anatomical_entity	orientation	defined_class
+http://purl.obolibrary.org/obo/UBERON_0000979	http://purl.obolibrary.org/obo/PATO_0001592	http://purl.obolibrary.org/obo/UPHENO_0031090
+http://purl.obolibrary.org/obo/UBERON_0000976	http://purl.obolibrary.org/obo/PATO_0001592	http://purl.obolibrary.org/obo/UPHENO_0031093
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0000406	http://purl.obolibrary.org/obo/UPHENO_0031193
+http://purl.obolibrary.org/obo/UBERON_0035133	http://purl.obolibrary.org/obo/PATO_0001592	http://purl.obolibrary.org/obo/UPHENO_0031307
+http://purl.obolibrary.org/obo/UBERON_0002228	http://purl.obolibrary.org/obo/PATO_0002154	http://purl.obolibrary.org/obo/UPHENO_0031331
+http://purl.obolibrary.org/obo/UBERON_0001424	http://purl.obolibrary.org/obo/PATO_0001592	http://purl.obolibrary.org/obo/UPHENO_0031149
+http://purl.obolibrary.org/obo/UBERON_0001423	http://purl.obolibrary.org/obo/PATO_0001592	http://purl.obolibrary.org/obo/UPHENO_0031151
+http://purl.obolibrary.org/obo/UBERON_0010746	http://purl.obolibrary.org/obo/PATO_0000406	http://purl.obolibrary.org/obo/UPHENO_0031333
+http://purl.obolibrary.org/obo/UBERON_0005928	http://purl.obolibrary.org/obo/PATO_0001785	http://purl.obolibrary.org/obo/UPHENO_0031308
+http://purl.obolibrary.org/obo/UBERON_0013751	http://purl.obolibrary.org/obo/PATO_0000406	http://purl.obolibrary.org/obo/UPHENO_0031334
+http://purl.obolibrary.org/obo/UBERON_0003466	http://purl.obolibrary.org/obo/PATO_0001592	http://purl.obolibrary.org/obo/UPHENO_0031197
+http://purl.obolibrary.org/obo/UBERON_0005928	http://purl.obolibrary.org/obo/PATO_0000406	http://purl.obolibrary.org/obo/UPHENO_0031280
+http://purl.obolibrary.org/obo/UBERON_0007709	http://purl.obolibrary.org/obo/PATO_0000406	http://purl.obolibrary.org/obo/UPHENO_0031281
+http://purl.obolibrary.org/obo/UBERON_0000964	http://purl.obolibrary.org/obo/PATO_0001848	http://purl.obolibrary.org/obo/UPHENO_0031199
+http://purl.obolibrary.org/obo/UBERON_0000976	http://purl.obolibrary.org/obo/PATO_0000406	http://purl.obolibrary.org/obo/UPHENO_0031238
+http://purl.obolibrary.org/obo/UBERON_0003823	http://purl.obolibrary.org/obo/PATO_0000406	http://purl.obolibrary.org/obo/UPHENO_0031310
+http://purl.obolibrary.org/obo/UBERON_0001424	http://purl.obolibrary.org/obo/PATO_0000406	http://purl.obolibrary.org/obo/UPHENO_0031105
+http://purl.obolibrary.org/obo/UBERON_0007709	http://purl.obolibrary.org/obo/PATO_0001785	http://purl.obolibrary.org/obo/UPHENO_0031311
+http://purl.obolibrary.org/obo/UBERON_0006865	http://purl.obolibrary.org/obo/PATO_0001785	http://purl.obolibrary.org/obo/UPHENO_0031312
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0002154	http://purl.obolibrary.org/obo/UPHENO_0031294
+http://purl.obolibrary.org/obo/UBERON_0000979	http://purl.obolibrary.org/obo/PATO_0000406	http://purl.obolibrary.org/obo/UPHENO_0031245
+http://purl.obolibrary.org/obo/UBERON_0003252	http://purl.obolibrary.org/obo/PATO_0001785	http://purl.obolibrary.org/obo/UPHENO_0031335
+http://purl.obolibrary.org/obo/UBERON_0010746	http://purl.obolibrary.org/obo/PATO_0001785	http://purl.obolibrary.org/obo/UPHENO_0031295
+http://purl.obolibrary.org/obo/UBERON_0001423	http://purl.obolibrary.org/obo/PATO_0000406	http://purl.obolibrary.org/obo/UPHENO_0031115
+http://purl.obolibrary.org/obo/UBERON_0003466	http://purl.obolibrary.org/obo/PATO_0000406	http://purl.obolibrary.org/obo/UPHENO_0031169
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0001848	http://purl.obolibrary.org/obo/UPHENO_0031170
+http://purl.obolibrary.org/obo/UBERON_0013751	http://purl.obolibrary.org/obo/PATO_0001785	http://purl.obolibrary.org/obo/UPHENO_0031286
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0001649	http://purl.obolibrary.org/obo/UPHENO_0031253
+http://purl.obolibrary.org/obo/UBERON_0013749	http://purl.obolibrary.org/obo/PATO_0000406	http://purl.obolibrary.org/obo/UPHENO_0031319
+http://purl.obolibrary.org/obo/UBERON_0003252	http://purl.obolibrary.org/obo/PATO_0000406	http://purl.obolibrary.org/obo/UPHENO_0031320
+http://purl.obolibrary.org/obo/UBERON_0035133	http://purl.obolibrary.org/obo/PATO_0000406	http://purl.obolibrary.org/obo/UPHENO_0031321
+http://purl.obolibrary.org/obo/UBERON_0000981	http://purl.obolibrary.org/obo/PATO_0001592	http://purl.obolibrary.org/obo/UPHENO_0031177
+http://purl.obolibrary.org/obo/UBERON_0001437	http://purl.obolibrary.org/obo/PATO_0001785	http://purl.obolibrary.org/obo/UPHENO_0031340
+http://purl.obolibrary.org/obo/UBERON_0001438	http://purl.obolibrary.org/obo/PATO_0001785	http://purl.obolibrary.org/obo/UPHENO_0031341
+http://purl.obolibrary.org/obo/UBERON_0001437	http://purl.obolibrary.org/obo/PATO_0000406	http://purl.obolibrary.org/obo/UPHENO_0031298
+http://purl.obolibrary.org/obo/UBERON_0001438	http://purl.obolibrary.org/obo/PATO_0000406	http://purl.obolibrary.org/obo/UPHENO_0031299
+http://purl.obolibrary.org/obo/UBERON_0002228	http://purl.obolibrary.org/obo/PATO_0000406	http://purl.obolibrary.org/obo/UPHENO_0031130
+http://purl.obolibrary.org/obo/UBERON_0000964	http://purl.obolibrary.org/obo/PATO_0000406	http://purl.obolibrary.org/obo/UPHENO_0031129
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0001592	http://purl.obolibrary.org/obo/UPHENO_0031268
+http://purl.obolibrary.org/obo/UBERON_0003823	http://purl.obolibrary.org/obo/PATO_0001649	http://purl.obolibrary.org/obo/UPHENO_0031346
+http://purl.obolibrary.org/obo/UBERON_0006865	http://purl.obolibrary.org/obo/PATO_0000406	http://purl.obolibrary.org/obo/UPHENO_0031303
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0001785	http://purl.obolibrary.org/obo/UPHENO_0031135
+http://purl.obolibrary.org/obo/UBERON_0000981	http://purl.obolibrary.org/obo/PATO_0000406	http://purl.obolibrary.org/obo/UPHENO_0031137
+http://purl.obolibrary.org/obo/UBERON_0013749	http://purl.obolibrary.org/obo/PATO_0001785	http://purl.obolibrary.org/obo/UPHENO_0031290
diff --git a/src/curation/upheno-fillers/hp/abnormallyDecreasedCoilingOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/hp/abnormallyDecreasedCoilingOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..0ed976f6
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormallyDecreasedCoilingOfAnatomicalEntity.tsv
@@ -0,0 +1,3 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0079498
+http://purl.obolibrary.org/obo/UBERON_0001844	http://purl.obolibrary.org/obo/UPHENO_0079499
diff --git a/src/curation/upheno-fillers/hp/abnormallyDecreasedFunctionalityOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/hp/abnormallyDecreasedFunctionalityOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..3246aad2
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormallyDecreasedFunctionalityOfAnatomicalEntity.tsv
@@ -0,0 +1,17 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0066927
+http://purl.obolibrary.org/obo/UBERON_0004681	http://purl.obolibrary.org/obo/UPHENO_0066956
+http://purl.obolibrary.org/obo/CL_0000169	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0000992	http://purl.obolibrary.org/obo/UPHENO_0077799
+http://purl.obolibrary.org/obo/UBERON_0002369	http://purl.obolibrary.org/obo/UPHENO_0066940
+http://purl.obolibrary.org/obo/UBERON_0002589	http://purl.obolibrary.org/obo/UPHENO_0066957
+http://purl.obolibrary.org/obo/UBERON_0001231	http://purl.obolibrary.org/obo/UPHENO_0066943
+http://purl.obolibrary.org/obo/UBERON_0002110	http://purl.obolibrary.org/obo/UPHENO_0066949
+http://purl.obolibrary.org/obo/CL_0000084	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0000473	http://purl.obolibrary.org/obo/UPHENO_0066971
+http://purl.obolibrary.org/obo/UBERON_0000991	http://purl.obolibrary.org/obo/UPHENO_0066972
+http://purl.obolibrary.org/obo/UBERON_0002046	http://purl.obolibrary.org/obo/UPHENO_0066918
+http://purl.obolibrary.org/obo/UBERON_0002707	http://purl.obolibrary.org/obo/UPHENO_0066952
+http://purl.obolibrary.org/obo/UBERON_0002349	http://purl.obolibrary.org/obo/UPHENO_0077800
+http://purl.obolibrary.org/obo/UBERON_0002107	http://purl.obolibrary.org/obo/UPHENO_0066935
+http://purl.obolibrary.org/obo/CL_0000623	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/hp/abnormallyDecreasedFunctionalityOfAnatomicalEntityInLocation.tsv b/src/curation/upheno-fillers/hp/abnormallyDecreasedFunctionalityOfAnatomicalEntityInLocation.tsv
new file mode 100644
index 00000000..65b12082
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormallyDecreasedFunctionalityOfAnatomicalEntityInLocation.tsv
@@ -0,0 +1,5 @@
+anatomical_entity	entity	defined_class
+http://purl.obolibrary.org/obo/CL_0000540	http://purl.obolibrary.org/obo/BFO_0000004	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0001384	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/BFO_0000004	http://purl.obolibrary.org/obo/UPHENO_0024906
+http://purl.obolibrary.org/obo/CL_0000540	http://purl.obolibrary.org/obo/UBERON_0001384	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/hp/abnormallyDecreasedHeightOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/hp/abnormallyDecreasedHeightOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..eb215e5e
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormallyDecreasedHeightOfAnatomicalEntity.tsv
@@ -0,0 +1,5 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0080351
+http://purl.obolibrary.org/obo/UBERON_0001273	http://purl.obolibrary.org/obo/UPHENO_0080359
+http://purl.obolibrary.org/obo/UBERON_0000468	http://purl.obolibrary.org/obo/UPHENO_0080352
+http://purl.obolibrary.org/obo/UBERON_0001066	http://purl.obolibrary.org/obo/UPHENO_0080360
diff --git a/src/curation/upheno-fillers/hp/abnormallyDecreasedLengthOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/hp/abnormallyDecreasedLengthOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..2097b00d
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormallyDecreasedLengthOfAnatomicalEntity.tsv
@@ -0,0 +1,110 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0003654	http://purl.obolibrary.org/obo/UPHENO_0046607
+http://purl.obolibrary.org/obo/UBERON_0003652	http://purl.obolibrary.org/obo/UPHENO_0046608
+http://purl.obolibrary.org/obo/UBERON_0003653	http://purl.obolibrary.org/obo/UPHENO_0046609
+http://purl.obolibrary.org/obo/UBERON_0003650	http://purl.obolibrary.org/obo/UPHENO_0046610
+http://purl.obolibrary.org/obo/UBERON_0003651	http://purl.obolibrary.org/obo/UPHENO_0046612
+http://purl.obolibrary.org/obo/UBERON_0003649	http://purl.obolibrary.org/obo/UPHENO_0046614
+http://purl.obolibrary.org/obo/UBERON_0003647	http://purl.obolibrary.org/obo/UPHENO_0046615
+http://purl.obolibrary.org/obo/UBERON_0003648	http://purl.obolibrary.org/obo/UPHENO_0046616
+http://purl.obolibrary.org/obo/UBERON_0010222	http://purl.obolibrary.org/obo/UPHENO_0046504
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0046505
+http://purl.obolibrary.org/obo/UBERON_0004330	http://purl.obolibrary.org/obo/UPHENO_0046696
+http://purl.obolibrary.org/obo/UBERON_0004331	http://purl.obolibrary.org/obo/UPHENO_0046697
+http://purl.obolibrary.org/obo/UBERON_0003645	http://purl.obolibrary.org/obo/UPHENO_0046618
+http://purl.obolibrary.org/obo/UBERON_0004338	http://purl.obolibrary.org/obo/UPHENO_0046700
+http://purl.obolibrary.org/obo/UBERON_0001466	http://purl.obolibrary.org/obo/UPHENO_0046619
+http://purl.obolibrary.org/obo/UBERON_0003646	http://purl.obolibrary.org/obo/UPHENO_0046620
+http://purl.obolibrary.org/obo/UBERON_0001105	http://purl.obolibrary.org/obo/UPHENO_0046621
+http://purl.obolibrary.org/obo/UBERON_0004336	http://purl.obolibrary.org/obo/UPHENO_0079221
+http://purl.obolibrary.org/obo/UBERON_0015180	http://purl.obolibrary.org/obo/UPHENO_0046622
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+http://purl.obolibrary.org/obo/UBERON_0004326	http://purl.obolibrary.org/obo/UPHENO_0079230
+http://purl.obolibrary.org/obo/UBERON_0004323	http://purl.obolibrary.org/obo/UPHENO_0046710
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+http://purl.obolibrary.org/obo/UBERON_0003867	http://purl.obolibrary.org/obo/UPHENO_0046640
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+http://purl.obolibrary.org/obo/UBERON_0003868	http://purl.obolibrary.org/obo/UPHENO_0046642
+http://purl.obolibrary.org/obo/UBERON_0001449	http://purl.obolibrary.org/obo/UPHENO_0046641
+http://purl.obolibrary.org/obo/UBERON_0008878	http://purl.obolibrary.org/obo/UPHENO_0046643
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+http://purl.obolibrary.org/obo/UBERON_0003865	http://purl.obolibrary.org/obo/UPHENO_0046647
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+http://purl.obolibrary.org/obo/UBERON_0003624	http://purl.obolibrary.org/obo/UPHENO_0046648
+http://purl.obolibrary.org/obo/UBERON_0004317	http://purl.obolibrary.org/obo/UPHENO_0079235
+http://purl.obolibrary.org/obo/UBERON_0010709	http://purl.obolibrary.org/obo/UPHENO_0046649
+http://purl.obolibrary.org/obo/UBERON_0003866	http://purl.obolibrary.org/obo/UPHENO_0046650
+http://purl.obolibrary.org/obo/UBERON_0001443	http://purl.obolibrary.org/obo/UPHENO_0046651
+http://purl.obolibrary.org/obo/UBERON_0004314	http://purl.obolibrary.org/obo/UPHENO_0046724
+http://purl.obolibrary.org/obo/UBERON_0003863	http://purl.obolibrary.org/obo/UPHENO_0079236
+http://purl.obolibrary.org/obo/UBERON_0003622	http://purl.obolibrary.org/obo/UPHENO_0046652
+http://purl.obolibrary.org/obo/UBERON_0008199	http://purl.obolibrary.org/obo/UPHENO_0046432
+http://purl.obolibrary.org/obo/UBERON_0004315	http://purl.obolibrary.org/obo/UPHENO_0079237
+http://purl.obolibrary.org/obo/UBERON_0001445	http://purl.obolibrary.org/obo/UPHENO_0046653
+http://purl.obolibrary.org/obo/UBERON_0003864	http://purl.obolibrary.org/obo/UPHENO_0046655
+http://purl.obolibrary.org/obo/UBERON_0004312	http://purl.obolibrary.org/obo/UPHENO_0046725
+http://purl.obolibrary.org/obo/UBERON_0005402	http://purl.obolibrary.org/obo/UPHENO_0046536
+http://purl.obolibrary.org/obo/UBERON_0003466	http://purl.obolibrary.org/obo/UPHENO_0046540
+http://purl.obolibrary.org/obo/UBERON_0004313	http://purl.obolibrary.org/obo/UPHENO_0046726
+http://purl.obolibrary.org/obo/UBERON_0002495	http://purl.obolibrary.org/obo/UPHENO_0046538
+http://purl.obolibrary.org/obo/UBERON_0002374	http://purl.obolibrary.org/obo/UPHENO_0046539
+http://purl.obolibrary.org/obo/UBERON_0001681	http://purl.obolibrary.org/obo/UPHENO_0046435
+http://purl.obolibrary.org/obo/UBERON_0003862	http://purl.obolibrary.org/obo/UPHENO_0079238
+http://purl.obolibrary.org/obo/UBERON_0003620	http://purl.obolibrary.org/obo/UPHENO_0046656
+http://purl.obolibrary.org/obo/UBERON_0004311	http://purl.obolibrary.org/obo/UPHENO_0046727
+http://purl.obolibrary.org/obo/UBERON_0001834	http://purl.obolibrary.org/obo/UPHENO_0046731
+http://purl.obolibrary.org/obo/UBERON_0000981	http://purl.obolibrary.org/obo/UPHENO_0046560
+http://purl.obolibrary.org/obo/UBERON_0008341	http://purl.obolibrary.org/obo/UPHENO_0046734
+http://purl.obolibrary.org/obo/UBERON_0006689	http://purl.obolibrary.org/obo/UPHENO_0046667
+http://purl.obolibrary.org/obo/UBERON_0001705	http://purl.obolibrary.org/obo/UPHENO_0046568
+http://purl.obolibrary.org/obo/UBERON_0001706	http://purl.obolibrary.org/obo/UPHENO_0046570
+http://purl.obolibrary.org/obo/UBERON_0000974	http://purl.obolibrary.org/obo/UPHENO_0046571
+http://purl.obolibrary.org/obo/UBERON_0000975	http://purl.obolibrary.org/obo/UPHENO_0046572
+http://purl.obolibrary.org/obo/UBERON_0000976	http://purl.obolibrary.org/obo/UPHENO_0046573
+http://purl.obolibrary.org/obo/UBERON_0001702	http://purl.obolibrary.org/obo/UPHENO_0046574
+http://purl.obolibrary.org/obo/UBERON_0013771	http://purl.obolibrary.org/obo/UPHENO_0046675
+http://purl.obolibrary.org/obo/UBERON_0002471	http://purl.obolibrary.org/obo/UPHENO_0046745
+http://purl.obolibrary.org/obo/UBERON_0004657	http://purl.obolibrary.org/obo/UPHENO_0079239
+http://purl.obolibrary.org/obo/UBERON_0002234	http://purl.obolibrary.org/obo/UPHENO_0046748
+http://purl.obolibrary.org/obo/UBERON_0002228	http://purl.obolibrary.org/obo/UPHENO_0046582
+http://purl.obolibrary.org/obo/UBERON_0004769	http://purl.obolibrary.org/obo/UPHENO_0046752
+http://purl.obolibrary.org/obo/UBERON_0014852	http://purl.obolibrary.org/obo/UPHENO_0046681
+http://purl.obolibrary.org/obo/UBERON_0001819	http://purl.obolibrary.org/obo/UPHENO_0046753
+http://purl.obolibrary.org/obo/UBERON_0014851	http://purl.obolibrary.org/obo/UPHENO_0046687
+http://purl.obolibrary.org/obo/UBERON_0001130	http://purl.obolibrary.org/obo/UPHENO_0046589
+http://purl.obolibrary.org/obo/UBERON_0003677	http://purl.obolibrary.org/obo/UPHENO_0046597
+http://purl.obolibrary.org/obo/UBERON_0002100	http://purl.obolibrary.org/obo/UPHENO_0046758
+http://purl.obolibrary.org/obo/UBERON_0000043	http://purl.obolibrary.org/obo/UPHENO_0046759
+http://purl.obolibrary.org/obo/UBERON_0002101	http://purl.obolibrary.org/obo/UPHENO_0046600
+http://purl.obolibrary.org/obo/UBERON_0003701	http://purl.obolibrary.org/obo/UPHENO_0079240
+http://purl.obolibrary.org/obo/UBERON_0002336	http://purl.obolibrary.org/obo/UPHENO_0046761
+http://purl.obolibrary.org/obo/UBERON_0002331	http://purl.obolibrary.org/obo/UPHENO_0046604
diff --git a/src/curation/upheno-fillers/hp/abnormallyDecreasedLengthOfAnatomicalEntityAttachedToLocation.tsv b/src/curation/upheno-fillers/hp/abnormallyDecreasedLengthOfAnatomicalEntityAttachedToLocation.tsv
new file mode 100644
index 00000000..f057e6e6
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormallyDecreasedLengthOfAnatomicalEntityAttachedToLocation.tsv
@@ -0,0 +1,57 @@
+anatomical_entity	location	defined_class
+http://purl.obolibrary.org/obo/UBERON_0000043	http://purl.obolibrary.org/obo/UBERON_0007721	http://purl.obolibrary.org/obo/UPHENO_0081913
+http://purl.obolibrary.org/obo/UBERON_0000043	http://purl.obolibrary.org/obo/UBERON_0001464	http://purl.obolibrary.org/obo/UPHENO_0081915
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0007735	http://purl.obolibrary.org/obo/UPHENO_0081914
+http://purl.obolibrary.org/obo/UBERON_0000043	http://purl.obolibrary.org/obo/UBERON_0003839	http://purl.obolibrary.org/obo/UPHENO_0081916
+http://purl.obolibrary.org/obo/UBERON_0000043	http://purl.obolibrary.org/obo/UBERON_0001461	http://purl.obolibrary.org/obo/UPHENO_0081917
+http://purl.obolibrary.org/obo/UBERON_0000043	http://purl.obolibrary.org/obo/UBERON_0007723	http://purl.obolibrary.org/obo/UPHENO_0081918
+http://purl.obolibrary.org/obo/UBERON_0000043	http://purl.obolibrary.org/obo/UBERON_0001467	http://purl.obolibrary.org/obo/UPHENO_0081919
+http://purl.obolibrary.org/obo/UBERON_0000043	http://purl.obolibrary.org/obo/UBERON_0001466	http://purl.obolibrary.org/obo/UPHENO_0081921
+http://purl.obolibrary.org/obo/UBERON_0000043	http://purl.obolibrary.org/obo/UBERON_0001465	http://purl.obolibrary.org/obo/UPHENO_0081922
+http://purl.obolibrary.org/obo/UBERON_0000043	http://purl.obolibrary.org/obo/UBERON_0007762	http://purl.obolibrary.org/obo/UPHENO_0081923
+http://purl.obolibrary.org/obo/UBERON_0000043	http://purl.obolibrary.org/obo/UBERON_0004452	http://purl.obolibrary.org/obo/UPHENO_0081924
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0011265	http://purl.obolibrary.org/obo/UPHENO_0081925
+http://purl.obolibrary.org/obo/UBERON_0000043	http://purl.obolibrary.org/obo/UBERON_0007753	http://purl.obolibrary.org/obo/UPHENO_0081926
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0001467	http://purl.obolibrary.org/obo/UPHENO_0081927
+http://purl.obolibrary.org/obo/UBERON_0000043	http://purl.obolibrary.org/obo/UBERON_0007759	http://purl.obolibrary.org/obo/UPHENO_0081928
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0001461	http://purl.obolibrary.org/obo/UPHENO_0081929
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0014507	http://purl.obolibrary.org/obo/UPHENO_0081930
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0001466	http://purl.obolibrary.org/obo/UPHENO_0081931
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0007721	http://purl.obolibrary.org/obo/UPHENO_0081932
+http://purl.obolibrary.org/obo/UBERON_0000043	http://purl.obolibrary.org/obo/UBERON_0007756	http://purl.obolibrary.org/obo/UPHENO_0081933
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0001465	http://purl.obolibrary.org/obo/UPHENO_0081934
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0007723	http://purl.obolibrary.org/obo/UPHENO_0081935
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0003839	http://purl.obolibrary.org/obo/UPHENO_0081936
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0001464	http://purl.obolibrary.org/obo/UPHENO_0081938
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0014668	http://purl.obolibrary.org/obo/UPHENO_0081939
+http://purl.obolibrary.org/obo/UBERON_0000043	http://purl.obolibrary.org/obo/UBERON_0007750	http://purl.obolibrary.org/obo/UPHENO_0081940
+http://purl.obolibrary.org/obo/UBERON_0000043	http://purl.obolibrary.org/obo/UBERON_0002389	http://purl.obolibrary.org/obo/UPHENO_0081941
+http://purl.obolibrary.org/obo/UBERON_0000043	http://purl.obolibrary.org/obo/UBERON_0002544	http://purl.obolibrary.org/obo/UPHENO_0081942
+http://purl.obolibrary.org/obo/UBERON_0000043	http://purl.obolibrary.org/obo/UBERON_0011265	http://purl.obolibrary.org/obo/UPHENO_0081944
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0007762	http://purl.obolibrary.org/obo/UPHENO_0081943
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0004452	http://purl.obolibrary.org/obo/UPHENO_0081945
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0007759	http://purl.obolibrary.org/obo/UPHENO_0081946
+http://purl.obolibrary.org/obo/UBERON_0000043	http://purl.obolibrary.org/obo/UBERON_0007744	http://purl.obolibrary.org/obo/UPHENO_0081947
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0007753	http://purl.obolibrary.org/obo/UPHENO_0081948
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0002544	http://purl.obolibrary.org/obo/UPHENO_0081949
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0002389	http://purl.obolibrary.org/obo/UPHENO_0081950
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0014670	http://purl.obolibrary.org/obo/UPHENO_0081951
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0007756	http://purl.obolibrary.org/obo/UPHENO_0081952
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0014672	http://purl.obolibrary.org/obo/UPHENO_0081953
+http://purl.obolibrary.org/obo/UBERON_0000043	http://purl.obolibrary.org/obo/UBERON_0014668	http://purl.obolibrary.org/obo/UPHENO_0081954
+http://purl.obolibrary.org/obo/UBERON_0000043	http://purl.obolibrary.org/obo/UBERON_0007741	http://purl.obolibrary.org/obo/UPHENO_0081955
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0007750	http://purl.obolibrary.org/obo/UPHENO_0081956
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0014674	http://purl.obolibrary.org/obo/UPHENO_0081957
+http://purl.obolibrary.org/obo/UBERON_0000043	http://purl.obolibrary.org/obo/UBERON_0007747	http://purl.obolibrary.org/obo/UPHENO_0081958
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0014675	http://purl.obolibrary.org/obo/UPHENO_0081959
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0014508	http://purl.obolibrary.org/obo/UPHENO_0081960
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0007747	http://purl.obolibrary.org/obo/UPHENO_0081961
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0007744	http://purl.obolibrary.org/obo/UPHENO_0081962
+http://purl.obolibrary.org/obo/UBERON_0000043	http://purl.obolibrary.org/obo/UBERON_0014670	http://purl.obolibrary.org/obo/UPHENO_0081963
+http://purl.obolibrary.org/obo/UBERON_0000043	http://purl.obolibrary.org/obo/UBERON_0014508	http://purl.obolibrary.org/obo/UPHENO_0081964
+http://purl.obolibrary.org/obo/UBERON_0000043	http://purl.obolibrary.org/obo/UBERON_0014675	http://purl.obolibrary.org/obo/UPHENO_0081965
+http://purl.obolibrary.org/obo/UBERON_0000043	http://purl.obolibrary.org/obo/UBERON_0014674	http://purl.obolibrary.org/obo/UPHENO_0081966
+http://purl.obolibrary.org/obo/UBERON_0000043	http://purl.obolibrary.org/obo/UBERON_0014672	http://purl.obolibrary.org/obo/UPHENO_0081967
+http://purl.obolibrary.org/obo/UBERON_0000043	http://purl.obolibrary.org/obo/UBERON_0014507	http://purl.obolibrary.org/obo/UPHENO_0081968
+http://purl.obolibrary.org/obo/UBERON_0000043	http://purl.obolibrary.org/obo/UBERON_0007735	http://purl.obolibrary.org/obo/UPHENO_0081969
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0007741	http://purl.obolibrary.org/obo/UPHENO_0081970
diff --git a/src/curation/upheno-fillers/hp/abnormallyDecreasedLevelOfChemicalEntity.tsv b/src/curation/upheno-fillers/hp/abnormallyDecreasedLevelOfChemicalEntity.tsv
new file mode 100644
index 00000000..15f6feeb
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormallyDecreasedLevelOfChemicalEntity.tsv
@@ -0,0 +1,23 @@
+chemical_entity	defined_class
+http://purl.obolibrary.org/obo/CHEBI_24431	http://purl.obolibrary.org/obo/UPHENO_0066739
+http://purl.obolibrary.org/obo/PR_Q15848	http://purl.obolibrary.org/obo/UPHENO_0081713
+http://purl.obolibrary.org/obo/PR_Q10469	http://purl.obolibrary.org/obo/UPHENO_0081714
+http://purl.obolibrary.org/obo/PR_000008175	http://purl.obolibrary.org/obo/UPHENO_0081715
+http://purl.obolibrary.org/obo/PR_000023661	http://purl.obolibrary.org/obo/UPHENO_0081716
+http://purl.obolibrary.org/obo/CHEBI_28384	http://purl.obolibrary.org/obo/UPHENO_0066789
+http://purl.obolibrary.org/obo/CHEBI_546807	http://purl.obolibrary.org/obo/UPHENO_0066788
+http://purl.obolibrary.org/obo/CHEBI_28115	http://purl.obolibrary.org/obo/UPHENO_0066790
+http://purl.obolibrary.org/obo/CHEBI_27300	http://purl.obolibrary.org/obo/UPHENO_0066743
+http://purl.obolibrary.org/obo/PR_000005061	http://purl.obolibrary.org/obo/UPHENO_0081717
+http://purl.obolibrary.org/obo/PR_P32754	http://purl.obolibrary.org/obo/UPHENO_0081718
+http://purl.obolibrary.org/obo/PR_000003964	http://purl.obolibrary.org/obo/UPHENO_0066782
+http://purl.obolibrary.org/obo/CHEBI_18408	http://purl.obolibrary.org/obo/UPHENO_0066783
+http://purl.obolibrary.org/obo/CHEBI_33234	http://purl.obolibrary.org/obo/UPHENO_0066785
+http://purl.obolibrary.org/obo/PR_000004089	http://purl.obolibrary.org/obo/UPHENO_0081719
+http://purl.obolibrary.org/obo/CHEBI_12777	http://purl.obolibrary.org/obo/UPHENO_0066786
+http://purl.obolibrary.org/obo/CHEBI_35584	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/PR_000003969	http://purl.obolibrary.org/obo/UPHENO_0066787
+http://purl.obolibrary.org/obo/PR_000012234	http://purl.obolibrary.org/obo/UPHENO_0081720
+http://purl.obolibrary.org/obo/PR_000003968	http://purl.obolibrary.org/obo/UPHENO_0080017
+http://purl.obolibrary.org/obo/PR_Q12882	http://purl.obolibrary.org/obo/UPHENO_0081721
+http://purl.obolibrary.org/obo/PR_P47989	http://purl.obolibrary.org/obo/UPHENO_0081722
diff --git a/src/curation/upheno-fillers/hp/abnormallyDecreasedLevelOfChemicalEntityInLocation.tsv b/src/curation/upheno-fillers/hp/abnormallyDecreasedLevelOfChemicalEntityInLocation.tsv
new file mode 100644
index 00000000..8fdbc368
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormallyDecreasedLevelOfChemicalEntityInLocation.tsv
@@ -0,0 +1,148 @@
+chemical_entity	location	defined_class
+http://purl.obolibrary.org/obo/CHEBI_25017	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0034145
+http://purl.obolibrary.org/obo/CHEBI_16865	http://purl.obolibrary.org/obo/UBERON_0001977	http://purl.obolibrary.org/obo/UPHENO_0034445
+http://purl.obolibrary.org/obo/CHEBI_24431	http://purl.obolibrary.org/obo/UBERON_0001630	http://purl.obolibrary.org/obo/UPHENO_0034446
+http://purl.obolibrary.org/obo/CHEBI_24431	http://purl.obolibrary.org/obo/CL_0000738	http://purl.obolibrary.org/obo/UPHENO_0034447
+http://purl.obolibrary.org/obo/CHEBI_17754	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0034157
+http://purl.obolibrary.org/obo/CHEBI_16070	http://purl.obolibrary.org/obo/UBERON_0001977	http://purl.obolibrary.org/obo/UPHENO_0034449
+http://purl.obolibrary.org/obo/CHEBI_28694	http://purl.obolibrary.org/obo/UBERON_0001088	http://purl.obolibrary.org/obo/UPHENO_0034450
+http://purl.obolibrary.org/obo/CHEBI_18248	http://purl.obolibrary.org/obo/UBERON_0001977	http://purl.obolibrary.org/obo/UPHENO_0034452
+http://purl.obolibrary.org/obo/CHEBI_18291	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CHEBI_3098	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0034453
+http://purl.obolibrary.org/obo/CHEBI_3892	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0034169
+http://purl.obolibrary.org/obo/CHEBI_16541	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0034170
+http://purl.obolibrary.org/obo/CHEBI_17196	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0034454
+http://purl.obolibrary.org/obo/CHEBI_23965	http://purl.obolibrary.org/obo/UBERON_0001977	http://purl.obolibrary.org/obo/UPHENO_0034455
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+http://purl.obolibrary.org/obo/PR_000049996	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0034509
+http://purl.obolibrary.org/obo/CHEBI_27584	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0034304
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+http://purl.obolibrary.org/obo/PR_000003809	http://purl.obolibrary.org/obo/UBERON_0000479	http://purl.obolibrary.org/obo/UPHENO_0076015
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+http://purl.obolibrary.org/obo/CHEBI_26667	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CHEBI_16526	http://purl.obolibrary.org/obo/UBERON_0012168	http://purl.obolibrary.org/obo/UPHENO_0076018
+http://purl.obolibrary.org/obo/CHEBI_16134	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0034376
+http://purl.obolibrary.org/obo/CHEBI_22984	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0034379
+http://purl.obolibrary.org/obo/CHEBI_27266	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0034385
+http://purl.obolibrary.org/obo/CHEBI_24431	http://purl.obolibrary.org/obo/UBERON_0012168	http://purl.obolibrary.org/obo/UPHENO_0076019
+http://purl.obolibrary.org/obo/CHEBI_15727	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0034530
+http://purl.obolibrary.org/obo/CHEBI_26216	http://purl.obolibrary.org/obo/UBERON_0001088	http://purl.obolibrary.org/obo/UPHENO_0034393
+http://purl.obolibrary.org/obo/CHEBI_25107	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0034392
+http://purl.obolibrary.org/obo/CHEBI_15891	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0034397
+http://purl.obolibrary.org/obo/CHEBI_24431	http://purl.obolibrary.org/obo/UBERON_0001359	http://purl.obolibrary.org/obo/UPHENO_0034532
+http://purl.obolibrary.org/obo/CHEBI_15428	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0034402
+http://purl.obolibrary.org/obo/PR_000008894	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0084649
+http://purl.obolibrary.org/obo/CHEBI_29016	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0034405
+http://purl.obolibrary.org/obo/CHEBI_28044	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0034407
+http://purl.obolibrary.org/obo/CHEBI_28044	http://purl.obolibrary.org/obo/UBERON_0001359	http://purl.obolibrary.org/obo/UPHENO_0034534
+http://purl.obolibrary.org/obo/CHEBI_16990	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0034414
+http://purl.obolibrary.org/obo/CHEBI_16199	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0034413
+http://purl.obolibrary.org/obo/CHEBI_18257	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0034416
+http://purl.obolibrary.org/obo/CHEBI_18258	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0034418
+http://purl.obolibrary.org/obo/CHEBI_29016	http://purl.obolibrary.org/obo/UBERON_0001359	http://purl.obolibrary.org/obo/UPHENO_0034535
+http://purl.obolibrary.org/obo/CHEBI_17933	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0034536
+http://purl.obolibrary.org/obo/CHEBI_18243	http://purl.obolibrary.org/obo/UBERON_0001359	http://purl.obolibrary.org/obo/UPHENO_0034537
+http://purl.obolibrary.org/obo/CHEBI_50404	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0034539
+http://purl.obolibrary.org/obo/CHEBI_24431	http://purl.obolibrary.org/obo/UBERON_0001977	http://purl.obolibrary.org/obo/UPHENO_0034541
+http://purl.obolibrary.org/obo/CHEBI_17376	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0034542
+http://purl.obolibrary.org/obo/CHEBI_17823	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0034544
+http://purl.obolibrary.org/obo/CHEBI_16737	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0034434
+http://purl.obolibrary.org/obo/CHEBI_18237	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0034436
+http://purl.obolibrary.org/obo/CHEBI_17822	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0034439
+http://purl.obolibrary.org/obo/CHEBI_26020	http://purl.obolibrary.org/obo/UBERON_0001088	http://purl.obolibrary.org/obo/UPHENO_0034440
diff --git a/src/curation/upheno-fillers/hp/abnormallyDecreasedLevelOfChemicalEntityWithRoleInLocation.tsv b/src/curation/upheno-fillers/hp/abnormallyDecreasedLevelOfChemicalEntityWithRoleInLocation.tsv
new file mode 100644
index 00000000..6544e677
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormallyDecreasedLevelOfChemicalEntityWithRoleInLocation.tsv
@@ -0,0 +1,5 @@
+location	role	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001132	http://purl.obolibrary.org/obo/CHEBI_24621	http://purl.obolibrary.org/obo/UPHENO_0082552
+http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/CHEBI_50906	http://purl.obolibrary.org/obo/UPHENO_0079822
+http://purl.obolibrary.org/obo/UBERON_0001132	http://purl.obolibrary.org/obo/CHEBI_50906	http://purl.obolibrary.org/obo/UPHENO_0082553
+http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/CHEBI_50113	http://purl.obolibrary.org/obo/UPHENO_0079825
diff --git a/src/curation/upheno-fillers/hp/abnormallyDecreasedMassDensityOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/hp/abnormallyDecreasedMassDensityOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..4fd5960a
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormallyDecreasedMassDensityOfAnatomicalEntity.tsv
@@ -0,0 +1,3 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0082834
+http://purl.obolibrary.org/obo/UBERON_0001474	http://purl.obolibrary.org/obo/UPHENO_0082835
diff --git a/src/curation/upheno-fillers/hp/abnormallyDecreasedMassOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/hp/abnormallyDecreasedMassOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..6707185f
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormallyDecreasedMassOfAnatomicalEntity.tsv
@@ -0,0 +1,4 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0082761
+http://purl.obolibrary.org/obo/UBERON_0000468	http://purl.obolibrary.org/obo/UPHENO_0082794
+http://purl.obolibrary.org/obo/UBERON_0001630	http://purl.obolibrary.org/obo/UPHENO_0082752
diff --git a/src/curation/upheno-fillers/hp/abnormallyDecreasedMobilityOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/hp/abnormallyDecreasedMobilityOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..c770cffd
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormallyDecreasedMobilityOfAnatomicalEntity.tsv
@@ -0,0 +1,3 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0076671
+http://purl.obolibrary.org/obo/UBERON_0000982	http://purl.obolibrary.org/obo/UPHENO_0076672
diff --git a/src/curation/upheno-fillers/hp/abnormallyDecreasedNumberOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/hp/abnormallyDecreasedNumberOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..cb812684
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormallyDecreasedNumberOfAnatomicalEntity.tsv
@@ -0,0 +1,22 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0063722
+http://purl.obolibrary.org/obo/CL_0000233	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001091	http://purl.obolibrary.org/obo/UPHENO_0063844
+http://purl.obolibrary.org/obo/CL_0000576	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000169	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000236	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000038	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000775	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002412	http://purl.obolibrary.org/obo/UPHENO_0063766
+http://purl.obolibrary.org/obo/UBERON_0001820	http://purl.obolibrary.org/obo/UPHENO_0063819
+http://purl.obolibrary.org/obo/UBERON_0001285	http://purl.obolibrary.org/obo/UPHENO_0063776
+http://purl.obolibrary.org/obo/CL_0000084	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0005739	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0019246	http://purl.obolibrary.org/obo/UPHENO_0063897
+http://purl.obolibrary.org/obo/UBERON_0003704	http://purl.obolibrary.org/obo/UPHENO_0063894
+http://purl.obolibrary.org/obo/UBERON_0002228	http://purl.obolibrary.org/obo/UPHENO_0063827
+http://purl.obolibrary.org/obo/CL_0002559	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000556	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000623	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000767	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000558	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/hp/abnormallyDecreasedNumberOfAnatomicalEntityInLocation.tsv b/src/curation/upheno-fillers/hp/abnormallyDecreasedNumberOfAnatomicalEntityInLocation.tsv
new file mode 100644
index 00000000..7671b226
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormallyDecreasedNumberOfAnatomicalEntityInLocation.tsv
@@ -0,0 +1,34 @@
+anatomical_entity	location	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0001017	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0000004	http://purl.obolibrary.org/obo/UPHENO_0035123
+http://purl.obolibrary.org/obo/UBERON_0001013	http://purl.obolibrary.org/obo/UBERON_0013691	http://purl.obolibrary.org/obo/UPHENO_0035124
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0002100	http://purl.obolibrary.org/obo/UPHENO_0035181
+http://purl.obolibrary.org/obo/UBERON_0001013	http://purl.obolibrary.org/obo/UBERON_0010708	http://purl.obolibrary.org/obo/UPHENO_0035125
+http://purl.obolibrary.org/obo/UBERON_0002470	http://purl.obolibrary.org/obo/UBERON_0004288	http://purl.obolibrary.org/obo/UPHENO_0035182
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0004288	http://purl.obolibrary.org/obo/UPHENO_0035126
+http://purl.obolibrary.org/obo/UBERON_0001466	http://purl.obolibrary.org/obo/UBERON_0002387	http://purl.obolibrary.org/obo/UPHENO_0035127
+http://purl.obolibrary.org/obo/UBERON_0001013	http://purl.obolibrary.org/obo/UBERON_0010707	http://purl.obolibrary.org/obo/UPHENO_0035129
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0000975	http://purl.obolibrary.org/obo/UPHENO_0035162
+http://purl.obolibrary.org/obo/UBERON_0001013	http://purl.obolibrary.org/obo/UBERON_0000468	http://purl.obolibrary.org/obo/UPHENO_0035132
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0002387	http://purl.obolibrary.org/obo/UPHENO_0035134
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0002420	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0000956	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002190	http://purl.obolibrary.org/obo/UBERON_0002100	http://purl.obolibrary.org/obo/UPHENO_0035135
+http://purl.obolibrary.org/obo/CL_0000738	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0005928	http://purl.obolibrary.org/obo/UBERON_0000004	http://purl.obolibrary.org/obo/UPHENO_0035190
+http://purl.obolibrary.org/obo/CL_0000540	http://purl.obolibrary.org/obo/UBERON_0001017	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000771	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000094	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0010707	http://purl.obolibrary.org/obo/UPHENO_0035109
+http://purl.obolibrary.org/obo/CL_0000540	http://purl.obolibrary.org/obo/UBERON_0002420	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0001021	http://purl.obolibrary.org/obo/UPHENO_0035170
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000540	http://purl.obolibrary.org/obo/UBERON_0000956	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0006135	http://purl.obolibrary.org/obo/UBERON_0001021	http://purl.obolibrary.org/obo/UPHENO_0035198
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0013691	http://purl.obolibrary.org/obo/UPHENO_0035115
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0000468	http://purl.obolibrary.org/obo/UPHENO_0035147
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0010708	http://purl.obolibrary.org/obo/UPHENO_0035119
+http://purl.obolibrary.org/obo/CL_0000542	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002544	http://purl.obolibrary.org/obo/UBERON_0010707	http://purl.obolibrary.org/obo/UPHENO_0035205
+http://purl.obolibrary.org/obo/CL_0000765	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0010355	http://purl.obolibrary.org/obo/UBERON_0000975	http://purl.obolibrary.org/obo/UPHENO_0035208
diff --git a/src/curation/upheno-fillers/hp/abnormallyDecreasedNumberOfCellularComponent.tsv b/src/curation/upheno-fillers/hp/abnormallyDecreasedNumberOfCellularComponent.tsv
new file mode 100644
index 00000000..728c3936
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormallyDecreasedNumberOfCellularComponent.tsv
@@ -0,0 +1,3 @@
+cellular_component	defined_class
+http://purl.obolibrary.org/obo/GO_0005739	http://purl.obolibrary.org/obo/UPHENO_0046250
+http://purl.obolibrary.org/obo/GO_0005575	http://purl.obolibrary.org/obo/UPHENO_0046252
diff --git a/src/curation/upheno-fillers/hp/abnormallyDecreasedPositionOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/hp/abnormallyDecreasedPositionOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..8cdeaf2e
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormallyDecreasedPositionOfAnatomicalEntity.tsv
@@ -0,0 +1,4 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0081783
+http://purl.obolibrary.org/obo/UBERON_0002030	http://purl.obolibrary.org/obo/UPHENO_0081785
+http://purl.obolibrary.org/obo/UBERON_0001691	http://purl.obolibrary.org/obo/UPHENO_0081784
diff --git a/src/curation/upheno-fillers/hp/abnormallyDecreasedQualityOfBiologicalProcess.tsv b/src/curation/upheno-fillers/hp/abnormallyDecreasedQualityOfBiologicalProcess.tsv
new file mode 100644
index 00000000..bd790c2f
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormallyDecreasedQualityOfBiologicalProcess.tsv
@@ -0,0 +1,5 @@
+biological_process	defined_class
+http://purl.obolibrary.org/obo/GO_0006555	http://purl.obolibrary.org/obo/UPHENO_0052163
+http://purl.obolibrary.org/obo/GO_0007601	http://purl.obolibrary.org/obo/UPHENO_0052164
+http://purl.obolibrary.org/obo/GO_0043084	http://purl.obolibrary.org/obo/UPHENO_0082003
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UPHENO_0052178
diff --git a/src/curation/upheno-fillers/hp/abnormallyDecreasedQualityOfBiologicalProcessInLocation.tsv b/src/curation/upheno-fillers/hp/abnormallyDecreasedQualityOfBiologicalProcessInLocation.tsv
new file mode 100644
index 00000000..427143bb
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormallyDecreasedQualityOfBiologicalProcessInLocation.tsv
@@ -0,0 +1,15 @@
+biological_process	location	defined_class
+http://purl.obolibrary.org/obo/GO_0030432	http://purl.obolibrary.org/obo/UBERON_0001555	http://purl.obolibrary.org/obo/UPHENO_0081648
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0002517	http://purl.obolibrary.org/obo/UPHENO_0042778
+http://purl.obolibrary.org/obo/GO_0001503	http://purl.obolibrary.org/obo/UBERON_0004339	http://purl.obolibrary.org/obo/UPHENO_0042793
+http://purl.obolibrary.org/obo/GO_0001503	http://purl.obolibrary.org/obo/UBERON_0003129	http://purl.obolibrary.org/obo/UPHENO_0042794
+http://purl.obolibrary.org/obo/GO_0001503	http://purl.obolibrary.org/obo/UBERON_0002412	http://purl.obolibrary.org/obo/UPHENO_0042795
+http://purl.obolibrary.org/obo/GO_0001503	http://purl.obolibrary.org/obo/UBERON_0002413	http://purl.obolibrary.org/obo/UPHENO_0042796
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0001555	http://purl.obolibrary.org/obo/UPHENO_0081649
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0002412	http://purl.obolibrary.org/obo/UPHENO_0042781
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0004339	http://purl.obolibrary.org/obo/UPHENO_0042782
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0002413	http://purl.obolibrary.org/obo/UPHENO_0042783
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0003129	http://purl.obolibrary.org/obo/UPHENO_0042784
+http://purl.obolibrary.org/obo/GO_0001503	http://purl.obolibrary.org/obo/UBERON_0002517	http://purl.obolibrary.org/obo/UPHENO_0042785
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0000033	http://purl.obolibrary.org/obo/UPHENO_0042790
+http://purl.obolibrary.org/obo/GO_0035265	http://purl.obolibrary.org/obo/UBERON_0000033	http://purl.obolibrary.org/obo/UPHENO_0042792
diff --git a/src/curation/upheno-fillers/hp/abnormallyDecreasedRateOfBehavior.tsv b/src/curation/upheno-fillers/hp/abnormallyDecreasedRateOfBehavior.tsv
new file mode 100644
index 00000000..18a1246d
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormallyDecreasedRateOfBehavior.tsv
@@ -0,0 +1,8 @@
+behavior_process	defined_class
+http://purl.obolibrary.org/obo/NBO_0000313	http://purl.obolibrary.org/obo/UPHENO_0074360
+http://purl.obolibrary.org/obo/NBO_0000339	http://purl.obolibrary.org/obo/UPHENO_0074367
+http://purl.obolibrary.org/obo/NBO_0000604	http://purl.obolibrary.org/obo/UPHENO_0074396
+http://purl.obolibrary.org/obo/NBO_0000616	http://purl.obolibrary.org/obo/UPHENO_0074397
+http://purl.obolibrary.org/obo/NBO_0000075	http://purl.obolibrary.org/obo/UPHENO_0080063
+http://purl.obolibrary.org/obo/NBO_0000043	http://purl.obolibrary.org/obo/UPHENO_0074398
+http://purl.obolibrary.org/obo/NBO_0000233	http://purl.obolibrary.org/obo/UPHENO_0080064
diff --git a/src/curation/upheno-fillers/hp/abnormallyDecreasedRateOfBiologicalProcess.tsv b/src/curation/upheno-fillers/hp/abnormallyDecreasedRateOfBiologicalProcess.tsv
new file mode 100644
index 00000000..306e7afd
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormallyDecreasedRateOfBiologicalProcess.tsv
@@ -0,0 +1,31 @@
+biological_process	defined_class
+http://purl.obolibrary.org/obo/NBO_0000604	http://purl.obolibrary.org/obo/UPHENO_0080281
+http://purl.obolibrary.org/obo/GO_0007605	http://purl.obolibrary.org/obo/UPHENO_0005518
+http://purl.obolibrary.org/obo/GO_0006955	http://purl.obolibrary.org/obo/UPHENO_0005638
+http://purl.obolibrary.org/obo/GO_0042110	http://purl.obolibrary.org/obo/UPHENO_0005495
+http://purl.obolibrary.org/obo/GO_0009790	http://purl.obolibrary.org/obo/UPHENO_0005642
+http://purl.obolibrary.org/obo/GO_0002250	http://purl.obolibrary.org/obo/UPHENO_0005622
+http://purl.obolibrary.org/obo/GO_0006012	http://purl.obolibrary.org/obo/UPHENO_0005624
+http://purl.obolibrary.org/obo/GO_0014831	http://purl.obolibrary.org/obo/UPHENO_0080282
+http://purl.obolibrary.org/obo/GO_0060004	http://purl.obolibrary.org/obo/UPHENO_0005625
+http://purl.obolibrary.org/obo/GO_0060047	http://purl.obolibrary.org/obo/UPHENO_0005931
+http://purl.obolibrary.org/obo/NBO_0000075	http://purl.obolibrary.org/obo/UPHENO_0080283
+http://purl.obolibrary.org/obo/GO_0019221	http://purl.obolibrary.org/obo/UPHENO_0005643
+http://purl.obolibrary.org/obo/GO_0097722	http://purl.obolibrary.org/obo/UPHENO_0005523
+http://purl.obolibrary.org/obo/GO_0070166	http://purl.obolibrary.org/obo/UPHENO_0005627
+http://purl.obolibrary.org/obo/GO_0070227	http://purl.obolibrary.org/obo/UPHENO_0005645
+http://purl.obolibrary.org/obo/NBO_0000233	http://purl.obolibrary.org/obo/UPHENO_0080284
+http://purl.obolibrary.org/obo/GO_0055127	http://purl.obolibrary.org/obo/UPHENO_0076901
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+http://purl.obolibrary.org/obo/GO_0006000	http://purl.obolibrary.org/obo/UPHENO_0005630
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+http://purl.obolibrary.org/obo/GO_0006094	http://purl.obolibrary.org/obo/UPHENO_0005430
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UPHENO_0005433
+http://purl.obolibrary.org/obo/GO_0030252	http://purl.obolibrary.org/obo/UPHENO_0005652
+http://purl.obolibrary.org/obo/GO_0050881	http://purl.obolibrary.org/obo/UPHENO_0005507
+http://purl.obolibrary.org/obo/NBO_0000043	http://purl.obolibrary.org/obo/UPHENO_0080287
diff --git a/src/curation/upheno-fillers/hp/abnormallyDecreasedRateOfBiologicalProcessInLocation.tsv b/src/curation/upheno-fillers/hp/abnormallyDecreasedRateOfBiologicalProcessInLocation.tsv
new file mode 100644
index 00000000..74312560
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormallyDecreasedRateOfBiologicalProcessInLocation.tsv
@@ -0,0 +1,124 @@
+biological_process	location	defined_class
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0003867	http://purl.obolibrary.org/obo/UPHENO_0077900
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+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0001449	http://purl.obolibrary.org/obo/UPHENO_0077902
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+http://purl.obolibrary.org/obo/GO_0045453	http://purl.obolibrary.org/obo/UBERON_0001435	http://purl.obolibrary.org/obo/UPHENO_0078003
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0001705	http://purl.obolibrary.org/obo/UPHENO_0078004
+http://purl.obolibrary.org/obo/GO_0060004	http://purl.obolibrary.org/obo/UBERON_0011648	http://purl.obolibrary.org/obo/UPHENO_0078005
+http://purl.obolibrary.org/obo/GO_0060004	http://purl.obolibrary.org/obo/UBERON_0000964	http://purl.obolibrary.org/obo/UPHENO_0078006
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0004331	http://purl.obolibrary.org/obo/UPHENO_0078007
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0002395	http://purl.obolibrary.org/obo/UPHENO_0078008
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0004330	http://purl.obolibrary.org/obo/UPHENO_0078009
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+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0003645	http://purl.obolibrary.org/obo/UPHENO_0078011
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+http://purl.obolibrary.org/obo/GO_0043473	http://purl.obolibrary.org/obo/UBERON_0002097	http://purl.obolibrary.org/obo/UPHENO_0077885
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+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0004329	http://purl.obolibrary.org/obo/UPHENO_0078021
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0000007	http://purl.obolibrary.org/obo/UPHENO_0077887
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0003638	http://purl.obolibrary.org/obo/UPHENO_0078022
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0003639	http://purl.obolibrary.org/obo/UPHENO_0078023
+http://purl.obolibrary.org/obo/GO_0070977	http://purl.obolibrary.org/obo/UBERON_0004288	http://purl.obolibrary.org/obo/UPHENO_0078026
diff --git a/src/curation/upheno-fillers/hp/abnormallyDecreasedRateOfMolecularFunction.tsv b/src/curation/upheno-fillers/hp/abnormallyDecreasedRateOfMolecularFunction.tsv
new file mode 100644
index 00000000..20808ed9
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormallyDecreasedRateOfMolecularFunction.tsv
@@ -0,0 +1,3 @@
+molecular_function	defined_class
+http://purl.obolibrary.org/obo/GO_0003674	http://purl.obolibrary.org/obo/UPHENO_0066865
+http://purl.obolibrary.org/obo/GO_0004736	http://purl.obolibrary.org/obo/UPHENO_0066895
diff --git a/src/curation/upheno-fillers/hp/abnormallyDecreasedSizeOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/hp/abnormallyDecreasedSizeOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..cdf267be
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormallyDecreasedSizeOfAnatomicalEntity.tsv
@@ -0,0 +1,34 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0004385	http://purl.obolibrary.org/obo/UPHENO_0069498
+http://purl.obolibrary.org/obo/UBERON_0008788	http://purl.obolibrary.org/obo/UPHENO_0069465
+http://purl.obolibrary.org/obo/UBERON_0001091	http://purl.obolibrary.org/obo/UPHENO_0068923
+http://purl.obolibrary.org/obo/UBERON_0004382	http://purl.obolibrary.org/obo/UPHENO_0069500
+http://purl.obolibrary.org/obo/UBERON_0001732	http://purl.obolibrary.org/obo/UPHENO_0069533
+http://purl.obolibrary.org/obo/UBERON_0001456	http://purl.obolibrary.org/obo/UPHENO_0069206
+http://purl.obolibrary.org/obo/UBERON_0002221	http://purl.obolibrary.org/obo/UPHENO_0069128
+http://purl.obolibrary.org/obo/UBERON_0008200	http://purl.obolibrary.org/obo/UPHENO_0069441
+http://purl.obolibrary.org/obo/UBERON_0004387	http://purl.obolibrary.org/obo/UPHENO_0069504
+http://purl.obolibrary.org/obo/UBERON_0001431	http://purl.obolibrary.org/obo/UPHENO_0069505
+http://purl.obolibrary.org/obo/UBERON_0001155	http://purl.obolibrary.org/obo/UPHENO_0069088
+http://purl.obolibrary.org/obo/UBERON_0002420	http://purl.obolibrary.org/obo/UPHENO_0069214
+http://purl.obolibrary.org/obo/UBERON_0001430	http://purl.obolibrary.org/obo/UPHENO_0069506
+http://purl.obolibrary.org/obo/UBERON_0000956	http://purl.obolibrary.org/obo/UPHENO_0069563
+http://purl.obolibrary.org/obo/UBERON_0001723	http://purl.obolibrary.org/obo/UPHENO_0069376
+http://purl.obolibrary.org/obo/UBERON_0001987	http://purl.obolibrary.org/obo/UPHENO_0069344
+http://purl.obolibrary.org/obo/UBERON_0001427	http://purl.obolibrary.org/obo/UPHENO_0069512
+http://purl.obolibrary.org/obo/UBERON_0018604	http://purl.obolibrary.org/obo/UPHENO_0084441
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0068971
+http://purl.obolibrary.org/obo/UBERON_0004395	http://purl.obolibrary.org/obo/UPHENO_0069484
+http://purl.obolibrary.org/obo/UBERON_0007120	http://purl.obolibrary.org/obo/UPHENO_0069559
+http://purl.obolibrary.org/obo/UBERON_0004391	http://purl.obolibrary.org/obo/UPHENO_0069488
+http://purl.obolibrary.org/obo/UBERON_0002411	http://purl.obolibrary.org/obo/UPHENO_0069241
+http://purl.obolibrary.org/obo/UBERON_0002510	http://purl.obolibrary.org/obo/UPHENO_0069517
+http://purl.obolibrary.org/obo/UBERON_0003687	http://purl.obolibrary.org/obo/UPHENO_0069560
+http://purl.obolibrary.org/obo/UBERON_0010707	http://purl.obolibrary.org/obo/UPHENO_0069491
+http://purl.obolibrary.org/obo/UBERON_0008772	http://purl.obolibrary.org/obo/UPHENO_0069473
+http://purl.obolibrary.org/obo/UBERON_0000473	http://purl.obolibrary.org/obo/UPHENO_0069250
+http://purl.obolibrary.org/obo/UBERON_0002398	http://purl.obolibrary.org/obo/UPHENO_0069529
+http://purl.obolibrary.org/obo/UBERON_0001437	http://purl.obolibrary.org/obo/UPHENO_0069493
+http://purl.obolibrary.org/obo/UBERON_0000964	http://purl.obolibrary.org/obo/UPHENO_0069561
+http://purl.obolibrary.org/obo/UBERON_0000007	http://purl.obolibrary.org/obo/UPHENO_0069190
+http://purl.obolibrary.org/obo/UBERON_0010230	http://purl.obolibrary.org/obo/UPHENO_0069523
diff --git a/src/curation/upheno-fillers/hp/abnormallyDecreasedSizeOfAnatomicalEntityInLocation.tsv b/src/curation/upheno-fillers/hp/abnormallyDecreasedSizeOfAnatomicalEntityInLocation.tsv
new file mode 100644
index 00000000..9e06d027
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormallyDecreasedSizeOfAnatomicalEntityInLocation.tsv
@@ -0,0 +1,91 @@
+anatomical_entity	location	defined_class
+http://purl.obolibrary.org/obo/UBERON_0004387	http://purl.obolibrary.org/obo/UBERON_0003865	http://purl.obolibrary.org/obo/UPHENO_0012438
+http://purl.obolibrary.org/obo/UBERON_0004387	http://purl.obolibrary.org/obo/UBERON_0004311	http://purl.obolibrary.org/obo/UPHENO_0012532
+http://purl.obolibrary.org/obo/UBERON_0004387	http://purl.obolibrary.org/obo/UBERON_0004314	http://purl.obolibrary.org/obo/UPHENO_0012533
+http://purl.obolibrary.org/obo/UBERON_0004387	http://purl.obolibrary.org/obo/UBERON_0004312	http://purl.obolibrary.org/obo/UPHENO_0012535
+http://purl.obolibrary.org/obo/UBERON_0004387	http://purl.obolibrary.org/obo/UBERON_0003620	http://purl.obolibrary.org/obo/UPHENO_0012439
+http://purl.obolibrary.org/obo/UBERON_0001075	http://purl.obolibrary.org/obo/UBERON_0002413	http://purl.obolibrary.org/obo/UPHENO_0012473
+http://purl.obolibrary.org/obo/UBERON_0004387	http://purl.obolibrary.org/obo/UBERON_0004313	http://purl.obolibrary.org/obo/UPHENO_0012539
+http://purl.obolibrary.org/obo/UBERON_0001437	http://purl.obolibrary.org/obo/UBERON_0004336	http://purl.obolibrary.org/obo/UPHENO_0012327
+http://purl.obolibrary.org/obo/UBERON_0001437	http://purl.obolibrary.org/obo/UBERON_0004332	http://purl.obolibrary.org/obo/UPHENO_0012334
+http://purl.obolibrary.org/obo/UBERON_0001437	http://purl.obolibrary.org/obo/UBERON_0003640	http://purl.obolibrary.org/obo/UPHENO_0012203
+http://purl.obolibrary.org/obo/UBERON_0001437	http://purl.obolibrary.org/obo/UBERON_0004333	http://purl.obolibrary.org/obo/UPHENO_0012337
+http://purl.obolibrary.org/obo/UBERON_0004387	http://purl.obolibrary.org/obo/UBERON_0003622	http://purl.obolibrary.org/obo/UPHENO_0012442
+http://purl.obolibrary.org/obo/UBERON_0004387	http://purl.obolibrary.org/obo/UBERON_0003864	http://purl.obolibrary.org/obo/UPHENO_0012443
+http://purl.obolibrary.org/obo/UBERON_0001437	http://purl.obolibrary.org/obo/UBERON_0004334	http://purl.obolibrary.org/obo/UPHENO_0012347
+http://purl.obolibrary.org/obo/UBERON_0001437	http://purl.obolibrary.org/obo/UBERON_0004335	http://purl.obolibrary.org/obo/UPHENO_0012351
+http://purl.obolibrary.org/obo/UBERON_0001437	http://purl.obolibrary.org/obo/UBERON_0004318	http://purl.obolibrary.org/obo/UPHENO_0012270
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0004336	http://purl.obolibrary.org/obo/UPHENO_0012093
+http://purl.obolibrary.org/obo/UBERON_0001437	http://purl.obolibrary.org/obo/UBERON_0001449	http://purl.obolibrary.org/obo/UPHENO_0012094
+http://purl.obolibrary.org/obo/UBERON_0001437	http://purl.obolibrary.org/obo/UBERON_0004319	http://purl.obolibrary.org/obo/UPHENO_0012271
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0004337	http://purl.obolibrary.org/obo/UPHENO_0012095
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0004332	http://purl.obolibrary.org/obo/UPHENO_0012099
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0003640	http://purl.obolibrary.org/obo/UPHENO_0012477
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0004333	http://purl.obolibrary.org/obo/UPHENO_0012101
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0004338	http://purl.obolibrary.org/obo/UPHENO_0012102
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0004334	http://purl.obolibrary.org/obo/UPHENO_0012105
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0004335	http://purl.obolibrary.org/obo/UPHENO_0012106
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0002234	http://purl.obolibrary.org/obo/UPHENO_0012212
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0004329	http://purl.obolibrary.org/obo/UPHENO_0012108
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0003637	http://purl.obolibrary.org/obo/UPHENO_0012480
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0010708	http://purl.obolibrary.org/obo/UPHENO_0012274
+http://purl.obolibrary.org/obo/UBERON_0001437	http://purl.obolibrary.org/obo/UBERON_0003632	http://purl.obolibrary.org/obo/UPHENO_0012111
+http://purl.obolibrary.org/obo/UBERON_0001437	http://purl.obolibrary.org/obo/UBERON_0004325	http://purl.obolibrary.org/obo/UPHENO_0012278
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+http://purl.obolibrary.org/obo/UBERON_0001437	http://purl.obolibrary.org/obo/UBERON_0003634	http://purl.obolibrary.org/obo/UPHENO_0012121
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+http://purl.obolibrary.org/obo/UBERON_0001437	http://purl.obolibrary.org/obo/UBERON_0003635	http://purl.obolibrary.org/obo/UPHENO_0012123
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0004330	http://purl.obolibrary.org/obo/UPHENO_0012125
+http://purl.obolibrary.org/obo/UBERON_0001437	http://purl.obolibrary.org/obo/UBERON_0004324	http://purl.obolibrary.org/obo/UPHENO_0012292
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0004331	http://purl.obolibrary.org/obo/UPHENO_0012128
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+http://purl.obolibrary.org/obo/UBERON_0004387	http://purl.obolibrary.org/obo/UBERON_0004338	http://purl.obolibrary.org/obo/UPHENO_0012412
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+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0004321	http://purl.obolibrary.org/obo/UPHENO_0012135
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+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0004327	http://purl.obolibrary.org/obo/UPHENO_0012139
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+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0004328	http://purl.obolibrary.org/obo/UPHENO_0012140
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+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0004319	http://purl.obolibrary.org/obo/UPHENO_0012145
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+http://purl.obolibrary.org/obo/UBERON_0001437	http://purl.obolibrary.org/obo/UBERON_0004315	http://purl.obolibrary.org/obo/UPHENO_0012359
+http://purl.obolibrary.org/obo/UBERON_0004387	http://purl.obolibrary.org/obo/UBERON_0004330	http://purl.obolibrary.org/obo/UPHENO_0012431
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+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0003622	http://purl.obolibrary.org/obo/UPHENO_0012517
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0003864	http://purl.obolibrary.org/obo/UPHENO_0012518
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0004315	http://purl.obolibrary.org/obo/UPHENO_0012156
+http://purl.obolibrary.org/obo/UBERON_0004387	http://purl.obolibrary.org/obo/UBERON_0004322	http://purl.obolibrary.org/obo/UPHENO_0012562
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0002374	http://purl.obolibrary.org/obo/UPHENO_0012157
+http://purl.obolibrary.org/obo/UBERON_0004387	http://purl.obolibrary.org/obo/UBERON_0004328	http://purl.obolibrary.org/obo/UPHENO_0012563
+http://purl.obolibrary.org/obo/UBERON_0004387	http://purl.obolibrary.org/obo/UBERON_0004323	http://purl.obolibrary.org/obo/UPHENO_0012565
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0004311	http://purl.obolibrary.org/obo/UPHENO_0012158
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0003865	http://purl.obolibrary.org/obo/UPHENO_0012519
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0004316	http://purl.obolibrary.org/obo/UPHENO_0012159
+http://purl.obolibrary.org/obo/UBERON_0004387	http://purl.obolibrary.org/obo/UBERON_0004321	http://purl.obolibrary.org/obo/UPHENO_0012568
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0004317	http://purl.obolibrary.org/obo/UPHENO_0012160
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0004312	http://purl.obolibrary.org/obo/UPHENO_0012165
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0004313	http://purl.obolibrary.org/obo/UPHENO_0012168
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0003620	http://purl.obolibrary.org/obo/UPHENO_0012525
+http://purl.obolibrary.org/obo/UBERON_0004387	http://purl.obolibrary.org/obo/UBERON_0003625	http://purl.obolibrary.org/obo/UPHENO_0012464
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0001449	http://purl.obolibrary.org/obo/UPHENO_0012526
+http://purl.obolibrary.org/obo/UBERON_0001437	http://purl.obolibrary.org/obo/UBERON_0010708	http://purl.obolibrary.org/obo/UPHENO_0012465
+http://purl.obolibrary.org/obo/UBERON_0004387	http://purl.obolibrary.org/obo/UBERON_0004320	http://purl.obolibrary.org/obo/UPHENO_0012576
diff --git a/src/curation/upheno-fillers/hp/abnormallyDecreasedStrengthOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/hp/abnormallyDecreasedStrengthOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..5bdaaa56
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormallyDecreasedStrengthOfAnatomicalEntity.tsv
@@ -0,0 +1,20 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0080555
+http://purl.obolibrary.org/obo/UBERON_0010952	http://purl.obolibrary.org/obo/UPHENO_0080561
+http://purl.obolibrary.org/obo/UBERON_0008856	http://purl.obolibrary.org/obo/UPHENO_0080562
+http://purl.obolibrary.org/obo/UBERON_0004481	http://purl.obolibrary.org/obo/UPHENO_0080563
+http://purl.obolibrary.org/obo/UBERON_0001103	http://purl.obolibrary.org/obo/UPHENO_0080564
+http://purl.obolibrary.org/obo/UBERON_0008196	http://purl.obolibrary.org/obo/UPHENO_0080565
+http://purl.obolibrary.org/obo/UBERON_0001630	http://purl.obolibrary.org/obo/UPHENO_0080556
+http://purl.obolibrary.org/obo/UBERON_0001377	http://purl.obolibrary.org/obo/UPHENO_0080566
+http://purl.obolibrary.org/obo/UBERON_0001578	http://purl.obolibrary.org/obo/UPHENO_0080567
+http://purl.obolibrary.org/obo/UBERON_0003897	http://purl.obolibrary.org/obo/UPHENO_0080568
+http://purl.obolibrary.org/obo/UBERON_0002377	http://purl.obolibrary.org/obo/UPHENO_0080569
+http://purl.obolibrary.org/obo/UBERON_0001497	http://purl.obolibrary.org/obo/UPHENO_0080570
+http://purl.obolibrary.org/obo/UBERON_0001111	http://purl.obolibrary.org/obo/UPHENO_0080571
+http://purl.obolibrary.org/obo/UBERON_0003706	http://purl.obolibrary.org/obo/UPHENO_0080572
+http://purl.obolibrary.org/obo/UBERON_0002988	http://purl.obolibrary.org/obo/UPHENO_0080573
+http://purl.obolibrary.org/obo/UBERON_0001601	http://purl.obolibrary.org/obo/UPHENO_0080574
+http://purl.obolibrary.org/obo/UBERON_0010890	http://purl.obolibrary.org/obo/UPHENO_0080575
+http://purl.obolibrary.org/obo/UBERON_0014376	http://purl.obolibrary.org/obo/UPHENO_0080576
+http://purl.obolibrary.org/obo/UBERON_0014398	http://purl.obolibrary.org/obo/UPHENO_0080577
diff --git a/src/curation/upheno-fillers/hp/abnormallyDecreasedThicknessOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/hp/abnormallyDecreasedThicknessOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..89454a1a
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormallyDecreasedThicknessOfAnatomicalEntity.tsv
@@ -0,0 +1,19 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0080790
+http://purl.obolibrary.org/obo/UBERON_0002097	http://purl.obolibrary.org/obo/UPHENO_0080843
+http://purl.obolibrary.org/obo/UBERON_0001037	http://purl.obolibrary.org/obo/UPHENO_0080844
+http://purl.obolibrary.org/obo/UBERON_0001773	http://purl.obolibrary.org/obo/UPHENO_0080812
+http://purl.obolibrary.org/obo/UBERON_0004339	http://purl.obolibrary.org/obo/UPHENO_0080845
+http://purl.obolibrary.org/obo/UBERON_0002488	http://purl.obolibrary.org/obo/UPHENO_0080846
+http://purl.obolibrary.org/obo/UBERON_0001105	http://purl.obolibrary.org/obo/UPHENO_0080847
+http://purl.obolibrary.org/obo/UBERON_0009565	http://purl.obolibrary.org/obo/UPHENO_0080848
+http://purl.obolibrary.org/obo/UBERON_0002387	http://purl.obolibrary.org/obo/UPHENO_0080849
+http://purl.obolibrary.org/obo/UBERON_0009567	http://purl.obolibrary.org/obo/UPHENO_0080850
+http://purl.obolibrary.org/obo/UBERON_0001705	http://purl.obolibrary.org/obo/UPHENO_0080851
+http://purl.obolibrary.org/obo/UBERON_0005928	http://purl.obolibrary.org/obo/UPHENO_0080852
+http://purl.obolibrary.org/obo/UBERON_0000964	http://purl.obolibrary.org/obo/UPHENO_0080805
+http://purl.obolibrary.org/obo/UBERON_0002228	http://purl.obolibrary.org/obo/UPHENO_0080807
+http://purl.obolibrary.org/obo/UBERON_0001439	http://purl.obolibrary.org/obo/UPHENO_0080840
+http://purl.obolibrary.org/obo/UBERON_0001835	http://purl.obolibrary.org/obo/UPHENO_0080853
+http://purl.obolibrary.org/obo/UBERON_0001834	http://purl.obolibrary.org/obo/UPHENO_0080841
+http://purl.obolibrary.org/obo/UBERON_0010163	http://purl.obolibrary.org/obo/UPHENO_0080854
diff --git a/src/curation/upheno-fillers/hp/abnormallyDecreasedTonicityOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/hp/abnormallyDecreasedTonicityOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..f86d3b2d
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormallyDecreasedTonicityOfAnatomicalEntity.tsv
@@ -0,0 +1,3 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0082555
+http://purl.obolibrary.org/obo/UBERON_0001630	http://purl.obolibrary.org/obo/UPHENO_0082557
diff --git a/src/curation/upheno-fillers/hp/abnormallyDecreasedVolumeOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/hp/abnormallyDecreasedVolumeOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..a929e11c
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormallyDecreasedVolumeOfAnatomicalEntity.tsv
@@ -0,0 +1,5 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0078429
+http://purl.obolibrary.org/obo/UBERON_0001905	http://purl.obolibrary.org/obo/UPHENO_0078439
+http://purl.obolibrary.org/obo/CL_0000233	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0004703	http://purl.obolibrary.org/obo/UPHENO_0078440
diff --git a/src/curation/upheno-fillers/hp/abnormallyDecreasedWeightOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/hp/abnormallyDecreasedWeightOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..3cfdf620
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormallyDecreasedWeightOfAnatomicalEntity.tsv
@@ -0,0 +1,4 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0054261
+http://purl.obolibrary.org/obo/UBERON_0000468	http://purl.obolibrary.org/obo/UPHENO_0054299
+http://purl.obolibrary.org/obo/UBERON_0001630	http://purl.obolibrary.org/obo/UPHENO_0054249
diff --git a/src/curation/upheno-fillers/hp/abnormallyDecreasedWidthOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/hp/abnormallyDecreasedWidthOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..44642169
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormallyDecreasedWidthOfAnatomicalEntity.tsv
@@ -0,0 +1,21 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0054567
+http://purl.obolibrary.org/obo/UBERON_0004099	http://purl.obolibrary.org/obo/UPHENO_0054626
+http://purl.obolibrary.org/obo/UBERON_0007830	http://purl.obolibrary.org/obo/UPHENO_0054632
+http://purl.obolibrary.org/obo/UBERON_0008878	http://purl.obolibrary.org/obo/UPHENO_0054653
+http://purl.obolibrary.org/obo/UBERON_0010746	http://purl.obolibrary.org/obo/UPHENO_0054654
+http://purl.obolibrary.org/obo/UBERON_0000004	http://purl.obolibrary.org/obo/UPHENO_0054644
+http://purl.obolibrary.org/obo/UBERON_0001456	http://purl.obolibrary.org/obo/UPHENO_0054588
+http://purl.obolibrary.org/obo/UBERON_0007119	http://purl.obolibrary.org/obo/UPHENO_0054645
+http://purl.obolibrary.org/obo/UBERON_0008200	http://purl.obolibrary.org/obo/UPHENO_0054646
+http://purl.obolibrary.org/obo/UBERON_0001352	http://purl.obolibrary.org/obo/UPHENO_0054621
+http://purl.obolibrary.org/obo/UBERON_0001681	http://purl.obolibrary.org/obo/UPHENO_0054660
+http://purl.obolibrary.org/obo/UBERON_0000165	http://purl.obolibrary.org/obo/UPHENO_0054647
+http://purl.obolibrary.org/obo/UBERON_0009973	http://purl.obolibrary.org/obo/UPHENO_0054648
+http://purl.obolibrary.org/obo/UBERON_0001705	http://purl.obolibrary.org/obo/UPHENO_0054623
+http://purl.obolibrary.org/obo/UBERON_0001716	http://purl.obolibrary.org/obo/UPHENO_0054610
+http://purl.obolibrary.org/obo/UBERON_0001706	http://purl.obolibrary.org/obo/UPHENO_0054562
+http://purl.obolibrary.org/obo/UBERON_0001734	http://purl.obolibrary.org/obo/UPHENO_0054629
+http://purl.obolibrary.org/obo/UBERON_0016416	http://purl.obolibrary.org/obo/UPHENO_0054665
+http://purl.obolibrary.org/obo/UBERON_0001819	http://purl.obolibrary.org/obo/UPHENO_0054577
+http://purl.obolibrary.org/obo/UBERON_0014411	http://purl.obolibrary.org/obo/UPHENO_0054631
diff --git a/src/curation/upheno-fillers/hp/abnormallyDelayedBiologicalProcess.tsv b/src/curation/upheno-fillers/hp/abnormallyDelayedBiologicalProcess.tsv
new file mode 100644
index 00000000..75db8505
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormallyDelayedBiologicalProcess.tsv
@@ -0,0 +1,9 @@
+biological_process	defined_class
+http://purl.obolibrary.org/obo/GO_0022011	http://purl.obolibrary.org/obo/UPHENO_0000551
+http://purl.obolibrary.org/obo/GO_0042713	http://purl.obolibrary.org/obo/UPHENO_0080536
+http://purl.obolibrary.org/obo/GO_0022010	http://purl.obolibrary.org/obo/UPHENO_0000552
+http://purl.obolibrary.org/obo/GO_0040007	http://purl.obolibrary.org/obo/UPHENO_0000541
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UPHENO_0000543
+http://purl.obolibrary.org/obo/GO_0042552	http://purl.obolibrary.org/obo/UPHENO_0000553
+http://purl.obolibrary.org/obo/GO_0042696	http://purl.obolibrary.org/obo/UPHENO_0000522
+http://purl.obolibrary.org/obo/GO_0045136	http://purl.obolibrary.org/obo/UPHENO_0000538
diff --git a/src/curation/upheno-fillers/hp/abnormallyDelayedBiologicalProcessInLocation.tsv b/src/curation/upheno-fillers/hp/abnormallyDelayedBiologicalProcessInLocation.tsv
new file mode 100644
index 00000000..1224959a
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormallyDelayedBiologicalProcessInLocation.tsv
@@ -0,0 +1,33 @@
+biological_process	location	defined_class
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0001427	http://purl.obolibrary.org/obo/UPHENO_0084019
+http://purl.obolibrary.org/obo/GO_0001503	http://purl.obolibrary.org/obo/UBERON_0004382	http://purl.obolibrary.org/obo/UPHENO_0084020
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0001447	http://purl.obolibrary.org/obo/UPHENO_0084021
+http://purl.obolibrary.org/obo/GO_0001503	http://purl.obolibrary.org/obo/UBERON_0001435	http://purl.obolibrary.org/obo/UPHENO_0084022
+http://purl.obolibrary.org/obo/GO_0001503	http://purl.obolibrary.org/obo/UBERON_0006767	http://purl.obolibrary.org/obo/UPHENO_0084023
+http://purl.obolibrary.org/obo/GO_0001503	http://purl.obolibrary.org/obo/UBERON_0004446	http://purl.obolibrary.org/obo/UPHENO_0084024
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0002395	http://purl.obolibrary.org/obo/UPHENO_0084025
+http://purl.obolibrary.org/obo/GO_0001503	http://purl.obolibrary.org/obo/UBERON_0001431	http://purl.obolibrary.org/obo/UPHENO_0084026
+http://purl.obolibrary.org/obo/GO_0001503	http://purl.obolibrary.org/obo/UBERON_0001450	http://purl.obolibrary.org/obo/UPHENO_0084027
+http://purl.obolibrary.org/obo/GO_0001503	http://purl.obolibrary.org/obo/UBERON_0002446	http://purl.obolibrary.org/obo/UPHENO_0084028
+http://purl.obolibrary.org/obo/GO_0001503	http://purl.obolibrary.org/obo/UBERON_0001275	http://purl.obolibrary.org/obo/UPHENO_0084029
+http://purl.obolibrary.org/obo/GO_0001503	http://purl.obolibrary.org/obo/UBERON_0001430	http://purl.obolibrary.org/obo/UPHENO_0084030
+http://purl.obolibrary.org/obo/GO_0001503	http://purl.obolibrary.org/obo/UBERON_0001447	http://purl.obolibrary.org/obo/UPHENO_0084031
+http://purl.obolibrary.org/obo/GO_0001503	http://purl.obolibrary.org/obo/UBERON_0001427	http://purl.obolibrary.org/obo/UPHENO_0084032
+http://purl.obolibrary.org/obo/GO_0001503	http://purl.obolibrary.org/obo/UBERON_0014444	http://purl.obolibrary.org/obo/UPHENO_0084033
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0001442	http://purl.obolibrary.org/obo/UPHENO_0084034
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0004412	http://purl.obolibrary.org/obo/UPHENO_0084035
+http://purl.obolibrary.org/obo/GO_0001503	http://purl.obolibrary.org/obo/UBERON_0002395	http://purl.obolibrary.org/obo/UPHENO_0084036
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0001437	http://purl.obolibrary.org/obo/UPHENO_0084037
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0014444	http://purl.obolibrary.org/obo/UPHENO_0084038
+http://purl.obolibrary.org/obo/GO_0001503	http://purl.obolibrary.org/obo/UBERON_0001442	http://purl.obolibrary.org/obo/UPHENO_0084039
+http://purl.obolibrary.org/obo/GO_0001503	http://purl.obolibrary.org/obo/UBERON_0004412	http://purl.obolibrary.org/obo/UPHENO_0084040
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0001435	http://purl.obolibrary.org/obo/UPHENO_0084041
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0004446	http://purl.obolibrary.org/obo/UPHENO_0084042
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0002446	http://purl.obolibrary.org/obo/UPHENO_0084044
+http://purl.obolibrary.org/obo/GO_0001503	http://purl.obolibrary.org/obo/UBERON_0001437	http://purl.obolibrary.org/obo/UPHENO_0084045
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0006767	http://purl.obolibrary.org/obo/UPHENO_0084046
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0004382	http://purl.obolibrary.org/obo/UPHENO_0084047
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0001431	http://purl.obolibrary.org/obo/UPHENO_0084048
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0001430	http://purl.obolibrary.org/obo/UPHENO_0084049
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0001275	http://purl.obolibrary.org/obo/UPHENO_0084050
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0001450	http://purl.obolibrary.org/obo/UPHENO_0084051
diff --git a/src/curation/upheno-fillers/hp/abnormallyDetachedAnatomicalEntities.tsv b/src/curation/upheno-fillers/hp/abnormallyDetachedAnatomicalEntities.tsv
new file mode 100644
index 00000000..3bdfd153
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormallyDetachedAnatomicalEntities.tsv
@@ -0,0 +1,12 @@
+anatomical_entity	anatomical_entity_detached_from	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0000966	http://purl.obolibrary.org/obo/UPHENO_0081670
+http://purl.obolibrary.org/obo/UBERON_0005273	http://purl.obolibrary.org/obo/UBERON_0001705	http://purl.obolibrary.org/obo/UPHENO_0081671
+http://purl.obolibrary.org/obo/UBERON_0005273	http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0081672
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0001705	http://purl.obolibrary.org/obo/UPHENO_0081673
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0081667
+http://purl.obolibrary.org/obo/UBERON_0010230	http://purl.obolibrary.org/obo/UBERON_0000966	http://purl.obolibrary.org/obo/UPHENO_0081674
+http://purl.obolibrary.org/obo/UBERON_0005273	http://purl.obolibrary.org/obo/UBERON_0009565	http://purl.obolibrary.org/obo/UPHENO_0081675
+http://purl.obolibrary.org/obo/UBERON_0010230	http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0081676
+http://purl.obolibrary.org/obo/UBERON_0005273	http://purl.obolibrary.org/obo/UBERON_0009567	http://purl.obolibrary.org/obo/UPHENO_0081677
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0009565	http://purl.obolibrary.org/obo/UPHENO_0081678
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0009567	http://purl.obolibrary.org/obo/UPHENO_0081679
diff --git a/src/curation/upheno-fillers/hp/abnormallyDilatedAnatomicalEntity.tsv b/src/curation/upheno-fillers/hp/abnormallyDilatedAnatomicalEntity.tsv
new file mode 100644
index 00000000..40a088fb
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormallyDilatedAnatomicalEntity.tsv
@@ -0,0 +1,12 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0084124
+http://purl.obolibrary.org/obo/UBERON_0002285	http://purl.obolibrary.org/obo/UPHENO_0084109
+http://purl.obolibrary.org/obo/UBERON_0011859	http://purl.obolibrary.org/obo/UPHENO_0084181
+http://purl.obolibrary.org/obo/UBERON_0001224	http://purl.obolibrary.org/obo/UPHENO_0084132
+http://purl.obolibrary.org/obo/UBERON_0002422	http://purl.obolibrary.org/obo/UPHENO_0084155
+http://purl.obolibrary.org/obo/UBERON_0001556	http://purl.obolibrary.org/obo/UPHENO_0084182
+http://purl.obolibrary.org/obo/UBERON_0001473	http://purl.obolibrary.org/obo/UPHENO_0084116
+http://purl.obolibrary.org/obo/UBERON_0009773	http://purl.obolibrary.org/obo/UPHENO_0084183
+http://purl.obolibrary.org/obo/UBERON_0002286	http://purl.obolibrary.org/obo/UPHENO_0084118
+http://purl.obolibrary.org/obo/UBERON_0005236	http://purl.obolibrary.org/obo/UPHENO_0084184
+http://purl.obolibrary.org/obo/UBERON_0001255	http://purl.obolibrary.org/obo/UPHENO_0084185
diff --git a/src/curation/upheno-fillers/hp/abnormallyDuplicatedAnatomicalEntity.tsv b/src/curation/upheno-fillers/hp/abnormallyDuplicatedAnatomicalEntity.tsv
new file mode 100644
index 00000000..b1b4607f
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormallyDuplicatedAnatomicalEntity.tsv
@@ -0,0 +1,13 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0075340
+http://purl.obolibrary.org/obo/UBERON_0010887	http://purl.obolibrary.org/obo/UPHENO_0075368
+http://purl.obolibrary.org/obo/UBERON_0005409	http://purl.obolibrary.org/obo/UPHENO_0075400
+http://purl.obolibrary.org/obo/UBERON_0004338	http://purl.obolibrary.org/obo/UPHENO_0075371
+http://purl.obolibrary.org/obo/UBERON_0003645	http://purl.obolibrary.org/obo/UPHENO_0075372
+http://purl.obolibrary.org/obo/UBERON_0001446	http://purl.obolibrary.org/obo/UPHENO_0075414
+http://purl.obolibrary.org/obo/UBERON_0004337	http://purl.obolibrary.org/obo/UPHENO_0075374
+http://purl.obolibrary.org/obo/UBERON_0010163	http://purl.obolibrary.org/obo/UPHENO_0075405
+http://purl.obolibrary.org/obo/UBERON_0010707	http://purl.obolibrary.org/obo/UPHENO_0075415
+http://purl.obolibrary.org/obo/UBERON_0004324	http://purl.obolibrary.org/obo/UPHENO_0075395
+http://purl.obolibrary.org/obo/UBERON_0001255	http://purl.obolibrary.org/obo/UPHENO_0077802
+http://purl.obolibrary.org/obo/UBERON_0003650	http://purl.obolibrary.org/obo/UPHENO_0075354
diff --git a/src/curation/upheno-fillers/hp/abnormallyDuplicatedAnatomicalEntityInLocation.tsv b/src/curation/upheno-fillers/hp/abnormallyDuplicatedAnatomicalEntityInLocation.tsv
new file mode 100644
index 00000000..a01a6358
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormallyDuplicatedAnatomicalEntityInLocation.tsv
@@ -0,0 +1,3 @@
+anatomical_entity	location	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0001435	http://purl.obolibrary.org/obo/UPHENO_0070526
+http://purl.obolibrary.org/obo/UBERON_0010355	http://purl.obolibrary.org/obo/UBERON_0001435	http://purl.obolibrary.org/obo/UPHENO_0070530
diff --git a/src/curation/upheno-fillers/hp/abnormallyEvertedAnatomicalEntity.tsv b/src/curation/upheno-fillers/hp/abnormallyEvertedAnatomicalEntity.tsv
new file mode 100644
index 00000000..94e40e3e
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormallyEvertedAnatomicalEntity.tsv
@@ -0,0 +1,8 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0080241
+http://purl.obolibrary.org/obo/UBERON_0001711	http://purl.obolibrary.org/obo/UPHENO_0080244
+http://purl.obolibrary.org/obo/UBERON_0001835	http://purl.obolibrary.org/obo/UPHENO_0080245
+http://purl.obolibrary.org/obo/UBERON_0001713	http://purl.obolibrary.org/obo/UPHENO_0080246
+http://purl.obolibrary.org/obo/UBERON_0001834	http://purl.obolibrary.org/obo/UPHENO_0080247
+http://purl.obolibrary.org/obo/UBERON_0001255	http://purl.obolibrary.org/obo/UPHENO_0080248
+http://purl.obolibrary.org/obo/UBERON_0016467	http://purl.obolibrary.org/obo/UPHENO_0080249
diff --git a/src/curation/upheno-fillers/hp/abnormallyFusedAnatomicalEntities.tsv b/src/curation/upheno-fillers/hp/abnormallyFusedAnatomicalEntities.tsv
new file mode 100644
index 00000000..6068f0a6
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormallyFusedAnatomicalEntities.tsv
@@ -0,0 +1,232 @@
+anatomical_entity	anatomical_entity_fused_with	defined_class
+http://purl.obolibrary.org/obo/UBERON_0004312	http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0078200
+http://purl.obolibrary.org/obo/UBERON_0004311	http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0078201
+http://purl.obolibrary.org/obo/UBERON_0002374	http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0078063
+http://purl.obolibrary.org/obo/UBERON_0004316	http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0078202
+http://purl.obolibrary.org/obo/UBERON_0004315	http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0078203
+http://purl.obolibrary.org/obo/UBERON_0004314	http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0078204
+http://purl.obolibrary.org/obo/UBERON_0004313	http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0078205
+http://purl.obolibrary.org/obo/UBERON_0004103	http://purl.obolibrary.org/obo/UBERON_0004103	http://purl.obolibrary.org/obo/UPHENO_0078069
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0004103	http://purl.obolibrary.org/obo/UPHENO_0078070
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0001833	http://purl.obolibrary.org/obo/UPHENO_0078071
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0002048	http://purl.obolibrary.org/obo/UPHENO_0078206
+http://purl.obolibrary.org/obo/UBERON_0001833	http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0078074
+http://purl.obolibrary.org/obo/UBERON_0004328	http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0078207
+http://purl.obolibrary.org/obo/UBERON_0004323	http://purl.obolibrary.org/obo/UBERON_0004331	http://purl.obolibrary.org/obo/UPHENO_0078208
+http://purl.obolibrary.org/obo/UBERON_0004323	http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0078209
+http://purl.obolibrary.org/obo/UBERON_0002387	http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0078210
+http://purl.obolibrary.org/obo/UBERON_0004322	http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0078211
+http://purl.obolibrary.org/obo/UBERON_0004321	http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0078212
+http://purl.obolibrary.org/obo/UBERON_0004320	http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0078213
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0004320	http://purl.obolibrary.org/obo/UPHENO_0078214
+http://purl.obolibrary.org/obo/UBERON_0002389	http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0078215
+http://purl.obolibrary.org/obo/UBERON_0004324	http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0078216
+http://purl.obolibrary.org/obo/UBERON_0003650	http://purl.obolibrary.org/obo/UBERON_0003650	http://purl.obolibrary.org/obo/UPHENO_0078217
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0002374	http://purl.obolibrary.org/obo/UPHENO_0078087
+http://purl.obolibrary.org/obo/UBERON_0001463	http://purl.obolibrary.org/obo/UBERON_0003622	http://purl.obolibrary.org/obo/UPHENO_0078218
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0004315	http://purl.obolibrary.org/obo/UPHENO_0078219
+http://purl.obolibrary.org/obo/UBERON_0014889	http://purl.obolibrary.org/obo/UBERON_0014890	http://purl.obolibrary.org/obo/UPHENO_0078220
+http://purl.obolibrary.org/obo/UBERON_0004333	http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0078221
+http://purl.obolibrary.org/obo/UBERON_0004332	http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0078222
+http://purl.obolibrary.org/obo/UBERON_0004331	http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0078223
+http://purl.obolibrary.org/obo/UBERON_0004612	http://purl.obolibrary.org/obo/UBERON_0004613	http://purl.obolibrary.org/obo/UPHENO_0078224
+http://purl.obolibrary.org/obo/UBERON_0003641	http://purl.obolibrary.org/obo/UBERON_0003641	http://purl.obolibrary.org/obo/UPHENO_0078225
+http://purl.obolibrary.org/obo/UBERON_0003642	http://purl.obolibrary.org/obo/UBERON_0003642	http://purl.obolibrary.org/obo/UPHENO_0078226
+http://purl.obolibrary.org/obo/UBERON_0003638	http://purl.obolibrary.org/obo/UBERON_0003638	http://purl.obolibrary.org/obo/UPHENO_0078227
+http://purl.obolibrary.org/obo/UBERON_0003639	http://purl.obolibrary.org/obo/UBERON_0003639	http://purl.obolibrary.org/obo/UPHENO_0078228
+http://purl.obolibrary.org/obo/UBERON_0003645	http://purl.obolibrary.org/obo/UBERON_0003645	http://purl.obolibrary.org/obo/UPHENO_0078229
+http://purl.obolibrary.org/obo/UBERON_0004338	http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0078230
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0004331	http://purl.obolibrary.org/obo/UPHENO_0078231
+http://purl.obolibrary.org/obo/UBERON_0004331	http://purl.obolibrary.org/obo/UBERON_0004331	http://purl.obolibrary.org/obo/UPHENO_0078232
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0004248	http://purl.obolibrary.org/obo/UPHENO_0078233
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0004249	http://purl.obolibrary.org/obo/UPHENO_0078234
+http://purl.obolibrary.org/obo/UBERON_0012476	http://purl.obolibrary.org/obo/UBERON_0012476	http://purl.obolibrary.org/obo/UPHENO_0078235
+http://purl.obolibrary.org/obo/UBERON_0004329	http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0078236
+http://purl.obolibrary.org/obo/UBERON_0012475	http://purl.obolibrary.org/obo/UBERON_0012475	http://purl.obolibrary.org/obo/UPHENO_0078237
+http://purl.obolibrary.org/obo/UBERON_0004103	http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0078121
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0001075	http://purl.obolibrary.org/obo/UPHENO_0078122
+http://purl.obolibrary.org/obo/UBERON_0013683	http://purl.obolibrary.org/obo/UBERON_0013684	http://purl.obolibrary.org/obo/UPHENO_0078238
+http://purl.obolibrary.org/obo/UBERON_0004614	http://purl.obolibrary.org/obo/UBERON_0004615	http://purl.obolibrary.org/obo/UPHENO_0078239
+http://purl.obolibrary.org/obo/UBERON_0003640	http://purl.obolibrary.org/obo/UBERON_0003640	http://purl.obolibrary.org/obo/UPHENO_0078240
+http://purl.obolibrary.org/obo/UBERON_0003636	http://purl.obolibrary.org/obo/UBERON_0003636	http://purl.obolibrary.org/obo/UPHENO_0078241
+http://purl.obolibrary.org/obo/UBERON_0003637	http://purl.obolibrary.org/obo/UBERON_0003637	http://purl.obolibrary.org/obo/UPHENO_0078242
+http://purl.obolibrary.org/obo/UBERON_0004333	http://purl.obolibrary.org/obo/UBERON_0004333	http://purl.obolibrary.org/obo/UPHENO_0078243
+http://purl.obolibrary.org/obo/UBERON_0004332	http://purl.obolibrary.org/obo/UBERON_0004332	http://purl.obolibrary.org/obo/UPHENO_0078244
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0078125
+http://purl.obolibrary.org/obo/UBERON_0004330	http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0078245
+http://purl.obolibrary.org/obo/UBERON_0001466	http://purl.obolibrary.org/obo/UBERON_0001466	http://purl.obolibrary.org/obo/UPHENO_0078246
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0004332	http://purl.obolibrary.org/obo/UPHENO_0078247
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0004333	http://purl.obolibrary.org/obo/UPHENO_0078248
+http://purl.obolibrary.org/obo/UBERON_0000979	http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0078249
+http://purl.obolibrary.org/obo/UBERON_0004328	http://purl.obolibrary.org/obo/UBERON_0004320	http://purl.obolibrary.org/obo/UPHENO_0078250
+http://purl.obolibrary.org/obo/UBERON_0001449	http://purl.obolibrary.org/obo/UBERON_0001449	http://purl.obolibrary.org/obo/UPHENO_0078251
+http://purl.obolibrary.org/obo/UBERON_0002387	http://purl.obolibrary.org/obo/UBERON_0002387	http://purl.obolibrary.org/obo/UPHENO_0078252
+http://purl.obolibrary.org/obo/UBERON_0002107	http://purl.obolibrary.org/obo/UBERON_0002048	http://purl.obolibrary.org/obo/UPHENO_0078253
+http://purl.obolibrary.org/obo/UBERON_0004322	http://purl.obolibrary.org/obo/UBERON_0004323	http://purl.obolibrary.org/obo/UPHENO_0078254
+http://purl.obolibrary.org/obo/UBERON_0003625	http://purl.obolibrary.org/obo/UBERON_0003624	http://purl.obolibrary.org/obo/UPHENO_0078255
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0011602	http://purl.obolibrary.org/obo/UPHENO_0078256
+http://purl.obolibrary.org/obo/UBERON_0004321	http://purl.obolibrary.org/obo/UBERON_0004323	http://purl.obolibrary.org/obo/UPHENO_0078257
+http://purl.obolibrary.org/obo/UBERON_0003633	http://purl.obolibrary.org/obo/UBERON_0003634	http://purl.obolibrary.org/obo/UPHENO_0078258
+http://purl.obolibrary.org/obo/UBERON_0003634	http://purl.obolibrary.org/obo/UBERON_0003635	http://purl.obolibrary.org/obo/UPHENO_0078259
+http://purl.obolibrary.org/obo/UBERON_0004324	http://purl.obolibrary.org/obo/UBERON_0004324	http://purl.obolibrary.org/obo/UPHENO_0078260
+http://purl.obolibrary.org/obo/UBERON_0004328	http://purl.obolibrary.org/obo/UBERON_0004328	http://purl.obolibrary.org/obo/UPHENO_0078261
+http://purl.obolibrary.org/obo/UBERON_0004323	http://purl.obolibrary.org/obo/UBERON_0004323	http://purl.obolibrary.org/obo/UPHENO_0078262
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0000982	http://purl.obolibrary.org/obo/UPHENO_0078139
+http://purl.obolibrary.org/obo/UBERON_0002347	http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0078149
+http://purl.obolibrary.org/obo/UBERON_0003867	http://purl.obolibrary.org/obo/UBERON_0003867	http://purl.obolibrary.org/obo/UPHENO_0078263
+http://purl.obolibrary.org/obo/UBERON_0003868	http://purl.obolibrary.org/obo/UBERON_0003868	http://purl.obolibrary.org/obo/UPHENO_0078264
+http://purl.obolibrary.org/obo/UBERON_0003631	http://purl.obolibrary.org/obo/UBERON_0003632	http://purl.obolibrary.org/obo/UPHENO_0078265
+http://purl.obolibrary.org/obo/UBERON_0003632	http://purl.obolibrary.org/obo/UBERON_0003633	http://purl.obolibrary.org/obo/UPHENO_0078266
+http://purl.obolibrary.org/obo/UBERON_0001448	http://purl.obolibrary.org/obo/UBERON_0001448	http://purl.obolibrary.org/obo/UPHENO_0078153
+http://purl.obolibrary.org/obo/UBERON_0001447	http://purl.obolibrary.org/obo/UBERON_0001447	http://purl.obolibrary.org/obo/UPHENO_0078155
+http://purl.obolibrary.org/obo/UBERON_0002389	http://purl.obolibrary.org/obo/UBERON_0002389	http://purl.obolibrary.org/obo/UPHENO_0078267
+http://purl.obolibrary.org/obo/UBERON_0004320	http://purl.obolibrary.org/obo/UBERON_0004328	http://purl.obolibrary.org/obo/UPHENO_0078268
+http://purl.obolibrary.org/obo/UBERON_0004329	http://purl.obolibrary.org/obo/UBERON_0004323	http://purl.obolibrary.org/obo/UPHENO_0078269
+http://purl.obolibrary.org/obo/UBERON_0001445	http://purl.obolibrary.org/obo/UBERON_0001445	http://purl.obolibrary.org/obo/UPHENO_0078270
+http://purl.obolibrary.org/obo/UBERON_0001442	http://purl.obolibrary.org/obo/UBERON_0001442	http://purl.obolibrary.org/obo/UPHENO_0078271
+http://purl.obolibrary.org/obo/UBERON_0001446	http://purl.obolibrary.org/obo/UBERON_0001446	http://purl.obolibrary.org/obo/UPHENO_0078272
+http://purl.obolibrary.org/obo/UBERON_0002413	http://purl.obolibrary.org/obo/UBERON_0002413	http://purl.obolibrary.org/obo/UPHENO_0078169
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+http://purl.obolibrary.org/obo/UBERON_0004249	http://purl.obolibrary.org/obo/UBERON_0004249	http://purl.obolibrary.org/obo/UPHENO_0078384
+http://purl.obolibrary.org/obo/UBERON_0004248	http://purl.obolibrary.org/obo/UBERON_0004248	http://purl.obolibrary.org/obo/UPHENO_0078385
+http://purl.obolibrary.org/obo/UBERON_0001448	http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0078161
+http://purl.obolibrary.org/obo/UBERON_0001449	http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0078386
+http://purl.obolibrary.org/obo/UBERON_0003868	http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0078387
+http://purl.obolibrary.org/obo/UBERON_0003625	http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0078388
+http://purl.obolibrary.org/obo/UBERON_0003867	http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0078389
+http://purl.obolibrary.org/obo/UBERON_0001447	http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0078163
+http://purl.obolibrary.org/obo/UBERON_0004014	http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0078390
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0003634	http://purl.obolibrary.org/obo/UPHENO_0078391
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0003635	http://purl.obolibrary.org/obo/UPHENO_0078392
+http://purl.obolibrary.org/obo/UBERON_0002234	http://purl.obolibrary.org/obo/UBERON_0003637	http://purl.obolibrary.org/obo/UPHENO_0078393
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0003632	http://purl.obolibrary.org/obo/UPHENO_0078394
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0003633	http://purl.obolibrary.org/obo/UPHENO_0078395
+http://purl.obolibrary.org/obo/UBERON_0001435	http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0078396
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0004014	http://purl.obolibrary.org/obo/UPHENO_0078397
diff --git a/src/curation/upheno-fillers/hp/abnormallyFusedAnatomicalEntitiesInLocation.tsv b/src/curation/upheno-fillers/hp/abnormallyFusedAnatomicalEntitiesInLocation.tsv
new file mode 100644
index 00000000..8be2fe14
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormallyFusedAnatomicalEntitiesInLocation.tsv
@@ -0,0 +1,9 @@
+anatomical_entity	anatomical_entity_fused_with	location	location_fused_with	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0002544	http://purl.obolibrary.org/obo/UBERON_0002544	http://purl.obolibrary.org/obo/UPHENO_0082657
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0001474	http://purl.obolibrary.org/obo/UBERON_0002544	http://purl.obolibrary.org/obo/UBERON_0002544	http://purl.obolibrary.org/obo/UPHENO_0082658
+http://purl.obolibrary.org/obo/UBERON_0001474	http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0002544	http://purl.obolibrary.org/obo/BFO_0000004	http://purl.obolibrary.org/obo/UPHENO_0082661
+http://purl.obolibrary.org/obo/UBERON_0001474	http://purl.obolibrary.org/obo/UBERON_0001474	http://purl.obolibrary.org/obo/UBERON_0002544	http://purl.obolibrary.org/obo/BFO_0000004	http://purl.obolibrary.org/obo/UPHENO_0082662
+http://purl.obolibrary.org/obo/UBERON_0001474	http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0002544	http://purl.obolibrary.org/obo/UBERON_0002544	http://purl.obolibrary.org/obo/UPHENO_0082663
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0002544	http://purl.obolibrary.org/obo/BFO_0000004	http://purl.obolibrary.org/obo/UPHENO_0082664
+http://purl.obolibrary.org/obo/UBERON_0001474	http://purl.obolibrary.org/obo/UBERON_0001474	http://purl.obolibrary.org/obo/UBERON_0002544	http://purl.obolibrary.org/obo/UBERON_0002544	http://purl.obolibrary.org/obo/UPHENO_0082665
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0001474	http://purl.obolibrary.org/obo/UBERON_0002544	http://purl.obolibrary.org/obo/BFO_0000004	http://purl.obolibrary.org/obo/UPHENO_0082666
diff --git a/src/curation/upheno-fillers/hp/abnormallyIncompleteClosureOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/hp/abnormallyIncompleteClosureOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..57c16ca7
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormallyIncompleteClosureOfAnatomicalEntity.tsv
@@ -0,0 +1,27 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0002085	http://purl.obolibrary.org/obo/UPHENO_0033559
+http://purl.obolibrary.org/obo/UBERON_0010358	http://purl.obolibrary.org/obo/UPHENO_0033626
+http://purl.obolibrary.org/obo/UBERON_0003216	http://purl.obolibrary.org/obo/UPHENO_0033564
+http://purl.obolibrary.org/obo/UBERON_0001775	http://purl.obolibrary.org/obo/UPHENO_0076303
+http://purl.obolibrary.org/obo/UBERON_0003697	http://purl.obolibrary.org/obo/UPHENO_0033616
+http://purl.obolibrary.org/obo/UBERON_0016442	http://purl.obolibrary.org/obo/UPHENO_0033617
+http://purl.obolibrary.org/obo/UBERON_0017671	http://purl.obolibrary.org/obo/UPHENO_0033629
+http://purl.obolibrary.org/obo/UBERON_0017670	http://purl.obolibrary.org/obo/UPHENO_0033630
+http://purl.obolibrary.org/obo/UBERON_0001769	http://purl.obolibrary.org/obo/UPHENO_0076304
+http://purl.obolibrary.org/obo/UBERON_0010262	http://purl.obolibrary.org/obo/UPHENO_0033618
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0033572
+http://purl.obolibrary.org/obo/UBERON_0003682	http://purl.obolibrary.org/obo/UPHENO_0033574
+http://purl.obolibrary.org/obo/UBERON_0005440	http://purl.obolibrary.org/obo/UPHENO_0033603
+http://purl.obolibrary.org/obo/UBERON_0002094	http://purl.obolibrary.org/obo/UPHENO_0033604
+http://purl.obolibrary.org/obo/UBERON_0001716	http://purl.obolibrary.org/obo/UPHENO_0033635
+http://purl.obolibrary.org/obo/UBERON_0001833	http://purl.obolibrary.org/obo/UPHENO_0033637
+http://purl.obolibrary.org/obo/UBERON_0000941	http://purl.obolibrary.org/obo/UPHENO_0076305
+http://purl.obolibrary.org/obo/UBERON_0001712	http://purl.obolibrary.org/obo/UPHENO_0076306
+http://purl.obolibrary.org/obo/UBERON_0001733	http://purl.obolibrary.org/obo/UPHENO_0033582
+http://purl.obolibrary.org/obo/UBERON_0001711	http://purl.obolibrary.org/obo/UPHENO_0033638
+http://purl.obolibrary.org/obo/UBERON_0012074	http://purl.obolibrary.org/obo/UPHENO_0033583
+http://purl.obolibrary.org/obo/UBERON_0001835	http://purl.obolibrary.org/obo/UPHENO_0033639
+http://purl.obolibrary.org/obo/UBERON_0000965	http://purl.obolibrary.org/obo/UPHENO_0076307
+http://purl.obolibrary.org/obo/UBERON_0001834	http://purl.obolibrary.org/obo/UPHENO_0033642
+http://purl.obolibrary.org/obo/UBERON_0001713	http://purl.obolibrary.org/obo/UPHENO_0076308
+http://purl.obolibrary.org/obo/UBERON_0010230	http://purl.obolibrary.org/obo/UPHENO_0033643
diff --git a/src/curation/upheno-fillers/hp/abnormallyIncreasedHeightOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/hp/abnormallyIncreasedHeightOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..f60507ed
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormallyIncreasedHeightOfAnatomicalEntity.tsv
@@ -0,0 +1,7 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0063513
+http://purl.obolibrary.org/obo/UBERON_0001716	http://purl.obolibrary.org/obo/UPHENO_0063527
+http://purl.obolibrary.org/obo/UBERON_0000468	http://purl.obolibrary.org/obo/UPHENO_0063528
+http://purl.obolibrary.org/obo/UBERON_0010746	http://purl.obolibrary.org/obo/UPHENO_0063534
+http://purl.obolibrary.org/obo/UBERON_0008200	http://purl.obolibrary.org/obo/UPHENO_0063525
+http://purl.obolibrary.org/obo/UBERON_0001066	http://purl.obolibrary.org/obo/UPHENO_0063537
diff --git a/src/curation/upheno-fillers/hp/abnormallyIncreasedHeightOfAnatomicalEntityInLocation.tsv b/src/curation/upheno-fillers/hp/abnormallyIncreasedHeightOfAnatomicalEntityInLocation.tsv
new file mode 100644
index 00000000..0877fd35
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormallyIncreasedHeightOfAnatomicalEntityInLocation.tsv
@@ -0,0 +1,3 @@
+anatomical_entity	location	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0002414	http://purl.obolibrary.org/obo/UPHENO_0034098
+http://purl.obolibrary.org/obo/UBERON_0001075	http://purl.obolibrary.org/obo/UBERON_0002414	http://purl.obolibrary.org/obo/UPHENO_0034103
diff --git a/src/curation/upheno-fillers/hp/abnormallyIncreasedLengthOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/hp/abnormallyIncreasedLengthOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..c34941cc
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormallyIncreasedLengthOfAnatomicalEntity.tsv
@@ -0,0 +1,44 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001350	http://purl.obolibrary.org/obo/UPHENO_0072333
+http://purl.obolibrary.org/obo/UBERON_0001691	http://purl.obolibrary.org/obo/UPHENO_0072352
+http://purl.obolibrary.org/obo/UBERON_0002389	http://purl.obolibrary.org/obo/UPHENO_0072353
+http://purl.obolibrary.org/obo/UBERON_0000004	http://purl.obolibrary.org/obo/UPHENO_0072356
+http://purl.obolibrary.org/obo/UBERON_0008341	http://purl.obolibrary.org/obo/UPHENO_0072388
+http://purl.obolibrary.org/obo/UBERON_0001456	http://purl.obolibrary.org/obo/UPHENO_0072219
+http://purl.obolibrary.org/obo/UBERON_0003631	http://purl.obolibrary.org/obo/UPHENO_0072357
+http://purl.obolibrary.org/obo/UBERON_0002387	http://purl.obolibrary.org/obo/UPHENO_0072358
+http://purl.obolibrary.org/obo/UBERON_0000979	http://purl.obolibrary.org/obo/UPHENO_0072269
+http://purl.obolibrary.org/obo/UBERON_0019255	http://purl.obolibrary.org/obo/UPHENO_0072360
+http://purl.obolibrary.org/obo/UBERON_0000974	http://purl.obolibrary.org/obo/UPHENO_0072272
+http://purl.obolibrary.org/obo/UBERON_0019254	http://purl.obolibrary.org/obo/UPHENO_0072361
+http://purl.obolibrary.org/obo/UBERON_0001702	http://purl.obolibrary.org/obo/UPHENO_0072394
+http://purl.obolibrary.org/obo/UBERON_0007709	http://purl.obolibrary.org/obo/UPHENO_0072366
+http://purl.obolibrary.org/obo/UBERON_0010163	http://purl.obolibrary.org/obo/UPHENO_0072367
+http://purl.obolibrary.org/obo/UBERON_0013678	http://purl.obolibrary.org/obo/UPHENO_0072226
+http://purl.obolibrary.org/obo/UBERON_0013771	http://purl.obolibrary.org/obo/UPHENO_0072395
+http://purl.obolibrary.org/obo/UBERON_0011575	http://purl.obolibrary.org/obo/UPHENO_0072413
+http://purl.obolibrary.org/obo/UBERON_0010222	http://purl.obolibrary.org/obo/UPHENO_0072194
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0072195
+http://purl.obolibrary.org/obo/UBERON_0008878	http://purl.obolibrary.org/obo/UPHENO_0072369
+http://purl.obolibrary.org/obo/UBERON_0003865	http://purl.obolibrary.org/obo/UPHENO_0072370
+http://purl.obolibrary.org/obo/UBERON_0001466	http://purl.obolibrary.org/obo/UPHENO_0072344
+http://purl.obolibrary.org/obo/UBERON_0003646	http://purl.obolibrary.org/obo/UPHENO_0072346
+http://purl.obolibrary.org/obo/UBERON_0001105	http://purl.obolibrary.org/obo/UPHENO_0072347
+http://purl.obolibrary.org/obo/UBERON_0001446	http://purl.obolibrary.org/obo/UPHENO_0072238
+http://purl.obolibrary.org/obo/UBERON_0001424	http://purl.obolibrary.org/obo/UPHENO_0072284
+http://purl.obolibrary.org/obo/UBERON_0001423	http://purl.obolibrary.org/obo/UPHENO_0072285
+http://purl.obolibrary.org/obo/UBERON_0003864	http://purl.obolibrary.org/obo/UPHENO_0072371
+http://purl.obolibrary.org/obo/UBERON_0008199	http://purl.obolibrary.org/obo/UPHENO_0072373
+http://purl.obolibrary.org/obo/UBERON_0005402	http://purl.obolibrary.org/obo/UPHENO_0072374
+http://purl.obolibrary.org/obo/UBERON_0002331	http://purl.obolibrary.org/obo/UPHENO_0072418
+http://purl.obolibrary.org/obo/UBERON_0002374	http://purl.obolibrary.org/obo/UPHENO_0072242
+http://purl.obolibrary.org/obo/UBERON_0001681	http://purl.obolibrary.org/obo/UPHENO_0082550
+http://purl.obolibrary.org/obo/UBERON_0002234	http://purl.obolibrary.org/obo/UPHENO_0072398
+http://purl.obolibrary.org/obo/UBERON_0000989	http://purl.obolibrary.org/obo/UPHENO_0072377
+http://purl.obolibrary.org/obo/UBERON_0001734	http://purl.obolibrary.org/obo/UPHENO_0072350
+http://purl.obolibrary.org/obo/UBERON_0001436	http://purl.obolibrary.org/obo/UPHENO_0072381
+http://purl.obolibrary.org/obo/UBERON_0001834	http://purl.obolibrary.org/obo/UPHENO_0072383
+http://purl.obolibrary.org/obo/UBERON_0013766	http://purl.obolibrary.org/obo/UPHENO_0072402
+http://purl.obolibrary.org/obo/UBERON_0001819	http://purl.obolibrary.org/obo/UPHENO_0072403
+http://purl.obolibrary.org/obo/UBERON_0014851	http://purl.obolibrary.org/obo/UPHENO_0072405
+http://purl.obolibrary.org/obo/UBERON_0035116	http://purl.obolibrary.org/obo/UPHENO_0072421
diff --git a/src/curation/upheno-fillers/hp/abnormallyIncreasedLevelOfChemicalEntity.tsv b/src/curation/upheno-fillers/hp/abnormallyIncreasedLevelOfChemicalEntity.tsv
new file mode 100644
index 00000000..d4cca233
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormallyIncreasedLevelOfChemicalEntity.tsv
@@ -0,0 +1,12 @@
+chemical_entity	defined_class
+http://purl.obolibrary.org/obo/CHEBI_84690	http://purl.obolibrary.org/obo/UPHENO_0048757
+http://purl.obolibrary.org/obo/PR_000003964	http://purl.obolibrary.org/obo/UPHENO_0048758
+http://purl.obolibrary.org/obo/PR_000013246	http://purl.obolibrary.org/obo/UPHENO_0048736
+http://purl.obolibrary.org/obo/CHEBI_24431	http://purl.obolibrary.org/obo/UPHENO_0048707
+http://purl.obolibrary.org/obo/PR_000003809	http://purl.obolibrary.org/obo/UPHENO_0048751
+http://purl.obolibrary.org/obo/PR_Q15848	http://purl.obolibrary.org/obo/UPHENO_0082942
+http://purl.obolibrary.org/obo/CHEBI_84125	http://purl.obolibrary.org/obo/UPHENO_0048752
+http://purl.obolibrary.org/obo/PR_000003969	http://purl.obolibrary.org/obo/UPHENO_0048760
+http://purl.obolibrary.org/obo/CHEBI_546807	http://purl.obolibrary.org/obo/UPHENO_0048753
+http://purl.obolibrary.org/obo/CHEBI_84118	http://purl.obolibrary.org/obo/UPHENO_0048755
+http://purl.obolibrary.org/obo/PR_000003968	http://purl.obolibrary.org/obo/UPHENO_0075666
diff --git a/src/curation/upheno-fillers/hp/abnormallyIncreasedLevelOfChemicalEntityInLocation.tsv b/src/curation/upheno-fillers/hp/abnormallyIncreasedLevelOfChemicalEntityInLocation.tsv
new file mode 100644
index 00000000..3672ade1
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormallyIncreasedLevelOfChemicalEntityInLocation.tsv
@@ -0,0 +1,352 @@
+chemical_entity	location	defined_class
+http://purl.obolibrary.org/obo/CHEBI_28087	http://purl.obolibrary.org/obo/UBERON_0002107	http://purl.obolibrary.org/obo/UPHENO_0067994
+http://purl.obolibrary.org/obo/CHEBI_28300	http://purl.obolibrary.org/obo/UBERON_0001088	http://purl.obolibrary.org/obo/UPHENO_0067995
+http://purl.obolibrary.org/obo/CHEBI_89843	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CHEBI_24431	http://purl.obolibrary.org/obo/CL_0000738	http://purl.obolibrary.org/obo/UPHENO_0068358
+http://purl.obolibrary.org/obo/CHEBI_18211	http://purl.obolibrary.org/obo/UBERON_0001969	http://purl.obolibrary.org/obo/UPHENO_0078532
+http://purl.obolibrary.org/obo/CHEBI_37024	http://purl.obolibrary.org/obo/UBERON_0001088	http://purl.obolibrary.org/obo/UPHENO_0068360
+http://purl.obolibrary.org/obo/CHEBI_28694	http://purl.obolibrary.org/obo/UBERON_0001088	http://purl.obolibrary.org/obo/UPHENO_0068361
+http://purl.obolibrary.org/obo/CHEBI_26271	http://purl.obolibrary.org/obo/UBERON_0001088	http://purl.obolibrary.org/obo/UPHENO_0068019
+http://purl.obolibrary.org/obo/CHEBI_35621	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CHEBI_33567	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0068363
+http://purl.obolibrary.org/obo/CHEBI_73018	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CHEBI_18248	http://purl.obolibrary.org/obo/UBERON_0001977	http://purl.obolibrary.org/obo/UPHENO_0068365
+http://purl.obolibrary.org/obo/CHEBI_545959	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CHEBI_18291	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CHEBI_30860	http://purl.obolibrary.org/obo/UBERON_0001088	http://purl.obolibrary.org/obo/UPHENO_0068023
+http://purl.obolibrary.org/obo/CHEBI_27226	http://purl.obolibrary.org/obo/UBERON_0001088	http://purl.obolibrary.org/obo/UPHENO_0068024
+http://purl.obolibrary.org/obo/CHEBI_48300	http://purl.obolibrary.org/obo/UBERON_0001359	http://purl.obolibrary.org/obo/UPHENO_0068366
+http://purl.obolibrary.org/obo/CHEBI_3892	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0068027
+http://purl.obolibrary.org/obo/CHEBI_23641	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0084757
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+http://purl.obolibrary.org/obo/CHEBI_18248	http://purl.obolibrary.org/obo/UBERON_0000955	http://purl.obolibrary.org/obo/UPHENO_0068353
+http://purl.obolibrary.org/obo/CHEBI_26708	http://purl.obolibrary.org/obo/GO_0005622	http://purl.obolibrary.org/obo/UPHENO_0068605
diff --git a/src/curation/upheno-fillers/hp/abnormallyIncreasedLevelOfChemicalEntityWithRoleInLocation.tsv b/src/curation/upheno-fillers/hp/abnormallyIncreasedLevelOfChemicalEntityWithRoleInLocation.tsv
new file mode 100644
index 00000000..53a9d8b6
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormallyIncreasedLevelOfChemicalEntityWithRoleInLocation.tsv
@@ -0,0 +1,11 @@
+location	role	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001132	http://purl.obolibrary.org/obo/CHEBI_24621	http://purl.obolibrary.org/obo/UPHENO_0082533
+http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/CHEBI_50906	http://purl.obolibrary.org/obo/UPHENO_0079534
+http://purl.obolibrary.org/obo/UBERON_0006314	http://purl.obolibrary.org/obo/CHEBI_22695	http://purl.obolibrary.org/obo/UPHENO_0082534
+http://purl.obolibrary.org/obo/UBERON_0001132	http://purl.obolibrary.org/obo/CHEBI_50906	http://purl.obolibrary.org/obo/UPHENO_0082535
+http://purl.obolibrary.org/obo/UBERON_0001977	http://purl.obolibrary.org/obo/CHEBI_50906	http://purl.obolibrary.org/obo/UPHENO_0082536
+http://purl.obolibrary.org/obo/UBERON_0001977	http://purl.obolibrary.org/obo/CHEBI_37527	http://purl.obolibrary.org/obo/UPHENO_0082537
+http://purl.obolibrary.org/obo/UBERON_0006314	http://purl.obolibrary.org/obo/CHEBI_50906	http://purl.obolibrary.org/obo/UPHENO_0082539
+http://purl.obolibrary.org/obo/UBERON_0001977	http://purl.obolibrary.org/obo/CHEBI_22695	http://purl.obolibrary.org/obo/UPHENO_0082541
+http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/CHEBI_50113	http://purl.obolibrary.org/obo/UPHENO_0079537
+http://purl.obolibrary.org/obo/UBERON_0006314	http://purl.obolibrary.org/obo/CHEBI_37527	http://purl.obolibrary.org/obo/UPHENO_0082543
diff --git a/src/curation/upheno-fillers/hp/abnormallyIncreasedMassDensityOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/hp/abnormallyIncreasedMassDensityOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..b7ddaf04
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormallyIncreasedMassDensityOfAnatomicalEntity.tsv
@@ -0,0 +1,6 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0084449
+http://purl.obolibrary.org/obo/UBERON_0001130	http://purl.obolibrary.org/obo/UPHENO_0084451
+http://purl.obolibrary.org/obo/UBERON_0004339	http://purl.obolibrary.org/obo/UPHENO_0084452
+http://purl.obolibrary.org/obo/UBERON_0002495	http://purl.obolibrary.org/obo/UPHENO_0084453
+http://purl.obolibrary.org/obo/UBERON_0001474	http://purl.obolibrary.org/obo/UPHENO_0084450
diff --git a/src/curation/upheno-fillers/hp/abnormallyIncreasedMobilityOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/hp/abnormallyIncreasedMobilityOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..a755c611
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormallyIncreasedMobilityOfAnatomicalEntity.tsv
@@ -0,0 +1,8 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0077419
+http://purl.obolibrary.org/obo/UBERON_0009768	http://purl.obolibrary.org/obo/UPHENO_0077420
+http://purl.obolibrary.org/obo/UBERON_0000982	http://purl.obolibrary.org/obo/UPHENO_0077421
+http://purl.obolibrary.org/obo/UBERON_0006658	http://purl.obolibrary.org/obo/UPHENO_0077422
+http://purl.obolibrary.org/obo/UBERON_0002413	http://purl.obolibrary.org/obo/UPHENO_0077423
+http://purl.obolibrary.org/obo/UBERON_0001486	http://purl.obolibrary.org/obo/UPHENO_0077424
+http://purl.obolibrary.org/obo/UBERON_0001485	http://purl.obolibrary.org/obo/UPHENO_0077425
diff --git a/src/curation/upheno-fillers/hp/abnormallyIncreasedNumberOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/hp/abnormallyIncreasedNumberOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..19a50c3a
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormallyIncreasedNumberOfAnatomicalEntity.tsv
@@ -0,0 +1,27 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001091	http://purl.obolibrary.org/obo/UPHENO_0014331
+http://purl.obolibrary.org/obo/UBERON_0001037	http://purl.obolibrary.org/obo/UPHENO_0014290
+http://purl.obolibrary.org/obo/UBERON_0001435	http://purl.obolibrary.org/obo/UPHENO_0014380
+http://purl.obolibrary.org/obo/UBERON_0002106	http://purl.obolibrary.org/obo/UPHENO_0014335
+http://purl.obolibrary.org/obo/CL_0000084	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0005739	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0005928	http://purl.obolibrary.org/obo/UPHENO_0014403
+http://purl.obolibrary.org/obo/UBERON_0001428	http://purl.obolibrary.org/obo/UPHENO_0014386
+http://purl.obolibrary.org/obo/UBERON_0001427	http://purl.obolibrary.org/obo/UPHENO_0014387
+http://purl.obolibrary.org/obo/CL_0000767	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0014240
+http://purl.obolibrary.org/obo/CL_0000097	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002030	http://purl.obolibrary.org/obo/UPHENO_0014242
+http://purl.obolibrary.org/obo/CL_0000891	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000576	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000038	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000236	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001466	http://purl.obolibrary.org/obo/UPHENO_0014440
+http://purl.obolibrary.org/obo/UBERON_0002412	http://purl.obolibrary.org/obo/UPHENO_0014273
+http://purl.obolibrary.org/obo/UBERON_0002374	http://purl.obolibrary.org/obo/UPHENO_0014409
+http://purl.obolibrary.org/obo/UBERON_0000473	http://purl.obolibrary.org/obo/UPHENO_0014410
+http://purl.obolibrary.org/obo/UBERON_0019246	http://purl.obolibrary.org/obo/UPHENO_0014412
+http://purl.obolibrary.org/obo/UBERON_0010171	http://purl.obolibrary.org/obo/UPHENO_0079538
+http://purl.obolibrary.org/obo/UBERON_0001711	http://purl.obolibrary.org/obo/UPHENO_0014415
+http://purl.obolibrary.org/obo/UBERON_0002228	http://purl.obolibrary.org/obo/UPHENO_0014316
+http://purl.obolibrary.org/obo/CL_0000558	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/hp/abnormallyIncreasedNumberOfAnatomicalEntityInLocation.tsv b/src/curation/upheno-fillers/hp/abnormallyIncreasedNumberOfAnatomicalEntityInLocation.tsv
new file mode 100644
index 00000000..86eeea22
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormallyIncreasedNumberOfAnatomicalEntityInLocation.tsv
@@ -0,0 +1,57 @@
+anatomical_entity	location	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0001435	http://purl.obolibrary.org/obo/UPHENO_0056295
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0006767	http://purl.obolibrary.org/obo/UPHENO_0056151
+http://purl.obolibrary.org/obo/UBERON_0002389	http://purl.obolibrary.org/obo/UBERON_0002398	http://purl.obolibrary.org/obo/UPHENO_0056197
+http://purl.obolibrary.org/obo/UBERON_0010355	http://purl.obolibrary.org/obo/UBERON_0002374	http://purl.obolibrary.org/obo/UPHENO_0056299
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0002488	http://purl.obolibrary.org/obo/UPHENO_0056198
+http://purl.obolibrary.org/obo/UBERON_0001474	http://purl.obolibrary.org/obo/UBERON_0002090	http://purl.obolibrary.org/obo/UPHENO_0056159
+http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UBERON_0001988	http://purl.obolibrary.org/obo/UPHENO_0056074
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0002090	http://purl.obolibrary.org/obo/UPHENO_0056252
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/CHEBI_15611	http://purl.obolibrary.org/obo/UPHENO_0079242
+http://purl.obolibrary.org/obo/UBERON_0001037	http://purl.obolibrary.org/obo/UBERON_0003101	http://purl.obolibrary.org/obo/UPHENO_0079244
+http://purl.obolibrary.org/obo/CL_0000775	http://purl.obolibrary.org/obo/UBERON_0001088	http://purl.obolibrary.org/obo/UPHENO_0084757
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+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0010707	http://purl.obolibrary.org/obo/UPHENO_0056257
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+http://purl.obolibrary.org/obo/UBERON_0003634	http://purl.obolibrary.org/obo/UBERON_0002387	http://purl.obolibrary.org/obo/UPHENO_0056263
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diff --git a/src/curation/upheno-fillers/hp/abnormallyIncreasedNumberOfCellularComponent.tsv b/src/curation/upheno-fillers/hp/abnormallyIncreasedNumberOfCellularComponent.tsv
new file mode 100644
index 00000000..69d487c1
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormallyIncreasedNumberOfCellularComponent.tsv
@@ -0,0 +1,3 @@
+cellular_component	defined_class
+http://purl.obolibrary.org/obo/GO_0005739	http://purl.obolibrary.org/obo/UPHENO_0063670
+http://purl.obolibrary.org/obo/GO_0005575	http://purl.obolibrary.org/obo/UPHENO_0063672
diff --git a/src/curation/upheno-fillers/hp/abnormallyIncreasedQualityOfBiologicalProcessInLocation.tsv b/src/curation/upheno-fillers/hp/abnormallyIncreasedQualityOfBiologicalProcessInLocation.tsv
new file mode 100644
index 00000000..d8e40e04
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormallyIncreasedQualityOfBiologicalProcessInLocation.tsv
@@ -0,0 +1,5 @@
+biological_process	location	defined_class
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0001555	http://purl.obolibrary.org/obo/UPHENO_0082678
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0003129	http://purl.obolibrary.org/obo/UPHENO_0082680
+http://purl.obolibrary.org/obo/GO_0030432	http://purl.obolibrary.org/obo/UBERON_0001555	http://purl.obolibrary.org/obo/UPHENO_0082681
+http://purl.obolibrary.org/obo/GO_0001503	http://purl.obolibrary.org/obo/UBERON_0003129	http://purl.obolibrary.org/obo/UPHENO_0082683
diff --git a/src/curation/upheno-fillers/hp/abnormallyIncreasedRateOfBehavior.tsv b/src/curation/upheno-fillers/hp/abnormallyIncreasedRateOfBehavior.tsv
new file mode 100644
index 00000000..715c233c
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormallyIncreasedRateOfBehavior.tsv
@@ -0,0 +1,4 @@
+behavior_process	defined_class
+http://purl.obolibrary.org/obo/NBO_0000620	http://purl.obolibrary.org/obo/UPHENO_0012084
+http://purl.obolibrary.org/obo/NBO_0000313	http://purl.obolibrary.org/obo/UPHENO_0012047
+http://purl.obolibrary.org/obo/NBO_0000608	http://purl.obolibrary.org/obo/UPHENO_0079820
diff --git a/src/curation/upheno-fillers/hp/abnormallyIncreasedRateOfBiologicalProcess.tsv b/src/curation/upheno-fillers/hp/abnormallyIncreasedRateOfBiologicalProcess.tsv
new file mode 100644
index 00000000..b59380ee
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormallyIncreasedRateOfBiologicalProcess.tsv
@@ -0,0 +1,12 @@
+biological_process	defined_class
+http://purl.obolibrary.org/obo/NBO_0000620	http://purl.obolibrary.org/obo/UPHENO_0082826
+http://purl.obolibrary.org/obo/GO_0060004	http://purl.obolibrary.org/obo/UPHENO_0055092
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UPHENO_0054970
+http://purl.obolibrary.org/obo/GO_0006955	http://purl.obolibrary.org/obo/UPHENO_0055096
+http://purl.obolibrary.org/obo/GO_0030252	http://purl.obolibrary.org/obo/UPHENO_0055017
+http://purl.obolibrary.org/obo/NBO_0000608	http://purl.obolibrary.org/obo/UPHENO_0082827
+http://purl.obolibrary.org/obo/GO_0042065	http://purl.obolibrary.org/obo/UPHENO_0076676
+http://purl.obolibrary.org/obo/GO_0070227	http://purl.obolibrary.org/obo/UPHENO_0055098
+http://purl.obolibrary.org/obo/GO_0042465	http://purl.obolibrary.org/obo/UPHENO_0076677
+http://purl.obolibrary.org/obo/GO_0046951	http://purl.obolibrary.org/obo/UPHENO_0055032
+http://purl.obolibrary.org/obo/GO_0060073	http://purl.obolibrary.org/obo/UPHENO_0055007
diff --git a/src/curation/upheno-fillers/hp/abnormallyIncreasedRateOfBiologicalProcessInLocation.tsv b/src/curation/upheno-fillers/hp/abnormallyIncreasedRateOfBiologicalProcessInLocation.tsv
new file mode 100644
index 00000000..6017f735
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormallyIncreasedRateOfBiologicalProcessInLocation.tsv
@@ -0,0 +1,114 @@
+biological_process	location	defined_class
+http://purl.obolibrary.org/obo/GO_0006954	http://purl.obolibrary.org/obo/UBERON_0002358	http://purl.obolibrary.org/obo/UPHENO_0074697
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+http://purl.obolibrary.org/obo/GO_0006954	http://purl.obolibrary.org/obo/UBERON_0000057	http://purl.obolibrary.org/obo/UPHENO_0074703
+http://purl.obolibrary.org/obo/GO_0006954	http://purl.obolibrary.org/obo/UBERON_0001301	http://purl.obolibrary.org/obo/UPHENO_0074599
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0005409	http://purl.obolibrary.org/obo/UPHENO_0074706
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0000996	http://purl.obolibrary.org/obo/UPHENO_0074709
+http://purl.obolibrary.org/obo/GO_0043473	http://purl.obolibrary.org/obo/UBERON_0004090	http://purl.obolibrary.org/obo/UPHENO_0074712
+http://purl.obolibrary.org/obo/GO_0006954	http://purl.obolibrary.org/obo/UBERON_0002107	http://purl.obolibrary.org/obo/UPHENO_0074713
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0002097	http://purl.obolibrary.org/obo/UPHENO_0074575
+http://purl.obolibrary.org/obo/GO_0006954	http://purl.obolibrary.org/obo/UBERON_0002113	http://purl.obolibrary.org/obo/UPHENO_0074714
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+http://purl.obolibrary.org/obo/GO_0060004	http://purl.obolibrary.org/obo/UBERON_0010709	http://purl.obolibrary.org/obo/UPHENO_0080033
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+http://purl.obolibrary.org/obo/GO_0006954	http://purl.obolibrary.org/obo/UBERON_0001173	http://purl.obolibrary.org/obo/UPHENO_0074605
+http://purl.obolibrary.org/obo/GO_0042065	http://purl.obolibrary.org/obo/UBERON_0002038	http://purl.obolibrary.org/obo/UPHENO_0080034
+http://purl.obolibrary.org/obo/GO_0043473	http://purl.obolibrary.org/obo/UBERON_0001786	http://purl.obolibrary.org/obo/UPHENO_0074606
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0001684	http://purl.obolibrary.org/obo/UPHENO_0080035
+http://purl.obolibrary.org/obo/GO_0006954	http://purl.obolibrary.org/obo/UBERON_0011220	http://purl.obolibrary.org/obo/UPHENO_0074609
+http://purl.obolibrary.org/obo/GO_0042065	http://purl.obolibrary.org/obo/UBERON_0002037	http://purl.obolibrary.org/obo/UPHENO_0080036
+http://purl.obolibrary.org/obo/GO_0008283	http://purl.obolibrary.org/obo/UBERON_0002319	http://purl.obolibrary.org/obo/UPHENO_0074610
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0001833	http://purl.obolibrary.org/obo/UPHENO_0074719
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0001711	http://purl.obolibrary.org/obo/UPHENO_0074720
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0002407	http://purl.obolibrary.org/obo/UPHENO_0074614
+http://purl.obolibrary.org/obo/GO_0006954	http://purl.obolibrary.org/obo/UBERON_0000996	http://purl.obolibrary.org/obo/UPHENO_0074616
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0002048	http://purl.obolibrary.org/obo/UPHENO_0074722
+http://purl.obolibrary.org/obo/GO_0006954	http://purl.obolibrary.org/obo/UBERON_0005409	http://purl.obolibrary.org/obo/UPHENO_0074622
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0002446	http://purl.obolibrary.org/obo/UPHENO_0081740
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+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0001255	http://purl.obolibrary.org/obo/UPHENO_0074694
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0000042	http://purl.obolibrary.org/obo/UPHENO_0074696
diff --git a/src/curation/upheno-fillers/hp/abnormallyIncreasedSizeOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/hp/abnormallyIncreasedSizeOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..6b573f01
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormallyIncreasedSizeOfAnatomicalEntity.tsv
@@ -0,0 +1,70 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0004385	http://purl.obolibrary.org/obo/UPHENO_0001496
+http://purl.obolibrary.org/obo/UBERON_0006683	http://purl.obolibrary.org/obo/UPHENO_0000993
+http://purl.obolibrary.org/obo/UBERON_0004382	http://purl.obolibrary.org/obo/UPHENO_0001499
+http://purl.obolibrary.org/obo/UBERON_0001433	http://purl.obolibrary.org/obo/UPHENO_0001501
+http://purl.obolibrary.org/obo/UBERON_0000982	http://purl.obolibrary.org/obo/UPHENO_0001543
+http://purl.obolibrary.org/obo/UBERON_0001432	http://purl.obolibrary.org/obo/UPHENO_0001502
+http://purl.obolibrary.org/obo/UBERON_0001435	http://purl.obolibrary.org/obo/UPHENO_0001503
+http://purl.obolibrary.org/obo/UBERON_0002369	http://purl.obolibrary.org/obo/UPHENO_0001145
+http://purl.obolibrary.org/obo/UBERON_0004387	http://purl.obolibrary.org/obo/UPHENO_0001505
+http://purl.obolibrary.org/obo/UBERON_0003695	http://purl.obolibrary.org/obo/UPHENO_0001545
+http://purl.obolibrary.org/obo/UBERON_0001078	http://purl.obolibrary.org/obo/UPHENO_0001521
+http://purl.obolibrary.org/obo/UBERON_0002046	http://purl.obolibrary.org/obo/UPHENO_0001070
+http://purl.obolibrary.org/obo/UBERON_0001987	http://purl.obolibrary.org/obo/UPHENO_0001374
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0001072
+http://purl.obolibrary.org/obo/UBERON_0001224	http://purl.obolibrary.org/obo/UPHENO_0001478
+http://purl.obolibrary.org/obo/UBERON_0002037	http://purl.obolibrary.org/obo/UPHENO_0001084
+http://purl.obolibrary.org/obo/UBERON_0002279	http://purl.obolibrary.org/obo/UPHENO_0001522
+http://purl.obolibrary.org/obo/UBERON_0003687	http://purl.obolibrary.org/obo/UPHENO_0001547
+http://purl.obolibrary.org/obo/UBERON_0002078	http://purl.obolibrary.org/obo/UPHENO_0001018
+http://purl.obolibrary.org/obo/UBERON_0001021	http://purl.obolibrary.org/obo/UPHENO_0001548
+http://purl.obolibrary.org/obo/UBERON_0004412	http://purl.obolibrary.org/obo/UPHENO_0001549
+http://purl.obolibrary.org/obo/UBERON_0002113	http://purl.obolibrary.org/obo/UPHENO_0001171
+http://purl.obolibrary.org/obo/UBERON_0004014	http://purl.obolibrary.org/obo/UPHENO_0001022
+http://purl.obolibrary.org/obo/UBERON_0004454	http://purl.obolibrary.org/obo/UPHENO_0001523
+http://purl.obolibrary.org/obo/UBERON_0002398	http://purl.obolibrary.org/obo/UPHENO_0001524
+http://purl.obolibrary.org/obo/UBERON_0002079	http://purl.obolibrary.org/obo/UPHENO_0001020
+http://purl.obolibrary.org/obo/UBERON_0001817	http://purl.obolibrary.org/obo/UPHENO_0001432
+http://purl.obolibrary.org/obo/UBERON_0000006	http://purl.obolibrary.org/obo/UPHENO_0001241
+http://purl.obolibrary.org/obo/UBERON_0000007	http://purl.obolibrary.org/obo/UPHENO_0001242
+http://purl.obolibrary.org/obo/UBERON_0002107	http://purl.obolibrary.org/obo/UPHENO_0001177
+http://purl.obolibrary.org/obo/UBERON_0000964	http://purl.obolibrary.org/obo/UPHENO_0001550
+http://purl.obolibrary.org/obo/UBERON_0004406	http://purl.obolibrary.org/obo/UPHENO_0001551
+http://purl.obolibrary.org/obo/UBERON_0007830	http://purl.obolibrary.org/obo/UPHENO_0001526
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+http://purl.obolibrary.org/obo/UBERON_0004086	http://purl.obolibrary.org/obo/UPHENO_0001440
+http://purl.obolibrary.org/obo/UBERON_0001091	http://purl.obolibrary.org/obo/UPHENO_0001034
+http://purl.obolibrary.org/obo/UBERON_0001732	http://purl.obolibrary.org/obo/UPHENO_0001528
+http://purl.obolibrary.org/obo/UBERON_0002106	http://purl.obolibrary.org/obo/UPHENO_0001189
+http://purl.obolibrary.org/obo/UBERON_0001456	http://purl.obolibrary.org/obo/UPHENO_0001260
+http://purl.obolibrary.org/obo/UBERON_0002221	http://purl.obolibrary.org/obo/UPHENO_0001192
+http://purl.obolibrary.org/obo/UBERON_0008200	http://purl.obolibrary.org/obo/UPHENO_0001452
+http://purl.obolibrary.org/obo/UBERON_0001098	http://purl.obolibrary.org/obo/UPHENO_0001512
+http://purl.obolibrary.org/obo/UBERON_0002421	http://purl.obolibrary.org/obo/UPHENO_0001481
+http://purl.obolibrary.org/obo/UBERON_0002420	http://purl.obolibrary.org/obo/UPHENO_0001264
+http://purl.obolibrary.org/obo/UBERON_0001847	http://purl.obolibrary.org/obo/UPHENO_0001531
+http://purl.obolibrary.org/obo/UBERON_0001723	http://purl.obolibrary.org/obo/UPHENO_0001398
+http://purl.obolibrary.org/obo/UBERON_0001447	http://purl.obolibrary.org/obo/UPHENO_0001484
+http://purl.obolibrary.org/obo/UBERON_0009767	http://purl.obolibrary.org/obo/UPHENO_0001556
+http://purl.obolibrary.org/obo/UBERON_0002293	http://purl.obolibrary.org/obo/UPHENO_0001515
+http://purl.obolibrary.org/obo/UBERON_0004395	http://purl.obolibrary.org/obo/UPHENO_0001486
+http://purl.obolibrary.org/obo/UBERON_0002372	http://purl.obolibrary.org/obo/UPHENO_0001536
+http://purl.obolibrary.org/obo/UBERON_0000074	http://purl.obolibrary.org/obo/UPHENO_0001537
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+http://purl.obolibrary.org/obo/UBERON_0004391	http://purl.obolibrary.org/obo/UPHENO_0001488
+http://purl.obolibrary.org/obo/UBERON_0000992	http://purl.obolibrary.org/obo/UPHENO_0001404
+http://purl.obolibrary.org/obo/UBERON_0001840	http://purl.obolibrary.org/obo/UPHENO_0001538
+http://purl.obolibrary.org/obo/UBERON_0001443	http://purl.obolibrary.org/obo/UPHENO_0001283
+http://purl.obolibrary.org/obo/UBERON_0002411	http://purl.obolibrary.org/obo/UPHENO_0001284
+http://purl.obolibrary.org/obo/UBERON_0006658	http://purl.obolibrary.org/obo/UPHENO_0001516
+http://purl.obolibrary.org/obo/UBERON_0000995	http://purl.obolibrary.org/obo/UPHENO_0001406
+http://purl.obolibrary.org/obo/UBERON_0000033	http://purl.obolibrary.org/obo/UPHENO_0001208
+http://purl.obolibrary.org/obo/UBERON_0001684	http://purl.obolibrary.org/obo/UPHENO_0001291
+http://purl.obolibrary.org/obo/UBERON_0000948	http://purl.obolibrary.org/obo/UPHENO_0001471
+http://purl.obolibrary.org/obo/UBERON_0001437	http://purl.obolibrary.org/obo/UPHENO_0001490
+http://purl.obolibrary.org/obo/UBERON_0004703	http://purl.obolibrary.org/obo/UPHENO_0001492
+http://purl.obolibrary.org/obo/UBERON_0001438	http://purl.obolibrary.org/obo/UPHENO_0001493
+http://purl.obolibrary.org/obo/UBERON_0010230	http://purl.obolibrary.org/obo/UPHENO_0001519
+http://purl.obolibrary.org/obo/UBERON_0016454	http://purl.obolibrary.org/obo/UPHENO_0001520
diff --git a/src/curation/upheno-fillers/hp/abnormallyIncreasedSizeOfAnatomicalEntityInLocation.tsv b/src/curation/upheno-fillers/hp/abnormallyIncreasedSizeOfAnatomicalEntityInLocation.tsv
new file mode 100644
index 00000000..fafbdf70
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormallyIncreasedSizeOfAnatomicalEntityInLocation.tsv
@@ -0,0 +1,89 @@
+anatomical_entity	location	defined_class
+http://purl.obolibrary.org/obo/UBERON_0004387	http://purl.obolibrary.org/obo/UBERON_0003865	http://purl.obolibrary.org/obo/UPHENO_0065497
+http://purl.obolibrary.org/obo/UBERON_0004387	http://purl.obolibrary.org/obo/UBERON_0004311	http://purl.obolibrary.org/obo/UPHENO_0065590
+http://purl.obolibrary.org/obo/UBERON_0004387	http://purl.obolibrary.org/obo/UBERON_0004314	http://purl.obolibrary.org/obo/UPHENO_0065591
+http://purl.obolibrary.org/obo/UBERON_0004387	http://purl.obolibrary.org/obo/UBERON_0004312	http://purl.obolibrary.org/obo/UPHENO_0065593
+http://purl.obolibrary.org/obo/UBERON_0004387	http://purl.obolibrary.org/obo/UBERON_0003620	http://purl.obolibrary.org/obo/UPHENO_0065498
+http://purl.obolibrary.org/obo/UBERON_0004387	http://purl.obolibrary.org/obo/UBERON_0004313	http://purl.obolibrary.org/obo/UPHENO_0065597
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0000975	http://purl.obolibrary.org/obo/UPHENO_0065500
+http://purl.obolibrary.org/obo/UBERON_0001437	http://purl.obolibrary.org/obo/UBERON_0004336	http://purl.obolibrary.org/obo/UPHENO_0065387
+http://purl.obolibrary.org/obo/UBERON_0005200	http://purl.obolibrary.org/obo/UBERON_0016410	http://purl.obolibrary.org/obo/UPHENO_0065602
+http://purl.obolibrary.org/obo/UBERON_0001437	http://purl.obolibrary.org/obo/UBERON_0004332	http://purl.obolibrary.org/obo/UPHENO_0065394
+http://purl.obolibrary.org/obo/UBERON_0001437	http://purl.obolibrary.org/obo/UBERON_0003640	http://purl.obolibrary.org/obo/UPHENO_0065260
+http://purl.obolibrary.org/obo/UBERON_0001437	http://purl.obolibrary.org/obo/UBERON_0004333	http://purl.obolibrary.org/obo/UPHENO_0065396
+http://purl.obolibrary.org/obo/UBERON_0004387	http://purl.obolibrary.org/obo/UBERON_0003622	http://purl.obolibrary.org/obo/UPHENO_0065501
+http://purl.obolibrary.org/obo/UBERON_0004387	http://purl.obolibrary.org/obo/UBERON_0003864	http://purl.obolibrary.org/obo/UPHENO_0065502
+http://purl.obolibrary.org/obo/UBERON_0001437	http://purl.obolibrary.org/obo/UBERON_0004334	http://purl.obolibrary.org/obo/UPHENO_0065406
+http://purl.obolibrary.org/obo/UBERON_0001437	http://purl.obolibrary.org/obo/UBERON_0004335	http://purl.obolibrary.org/obo/UPHENO_0065410
+http://purl.obolibrary.org/obo/UBERON_0001437	http://purl.obolibrary.org/obo/UBERON_0004318	http://purl.obolibrary.org/obo/UPHENO_0065328
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0004336	http://purl.obolibrary.org/obo/UPHENO_0065151
+http://purl.obolibrary.org/obo/UBERON_0001437	http://purl.obolibrary.org/obo/UBERON_0001449	http://purl.obolibrary.org/obo/UPHENO_0065152
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diff --git a/src/curation/upheno-fillers/hp/abnormallyIncreasedThicknessOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/hp/abnormallyIncreasedThicknessOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..b1ab03fa
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormallyIncreasedThicknessOfAnatomicalEntity.tsv
@@ -0,0 +1,25 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0047821
+http://purl.obolibrary.org/obo/UBERON_0001691	http://purl.obolibrary.org/obo/UPHENO_0047832
+http://purl.obolibrary.org/obo/UBERON_0002097	http://purl.obolibrary.org/obo/UPHENO_0047979
+http://purl.obolibrary.org/obo/UBERON_0002027	http://purl.obolibrary.org/obo/UPHENO_0047838
+http://purl.obolibrary.org/obo/UBERON_0001003	http://purl.obolibrary.org/obo/UPHENO_0047953
+http://purl.obolibrary.org/obo/UBERON_0001773	http://purl.obolibrary.org/obo/UPHENO_0048008
+http://purl.obolibrary.org/obo/UBERON_0003701	http://purl.obolibrary.org/obo/UPHENO_0048014
+http://purl.obolibrary.org/obo/UBERON_0004339	http://purl.obolibrary.org/obo/UPHENO_0047968
+http://purl.obolibrary.org/obo/UBERON_0002488	http://purl.obolibrary.org/obo/UPHENO_0047988
+http://purl.obolibrary.org/obo/UBERON_0002336	http://purl.obolibrary.org/obo/UPHENO_0048015
+http://purl.obolibrary.org/obo/UBERON_0004103	http://purl.obolibrary.org/obo/UPHENO_0047964
+http://purl.obolibrary.org/obo/UBERON_0009565	http://purl.obolibrary.org/obo/UPHENO_0047984
+http://purl.obolibrary.org/obo/UBERON_0009567	http://purl.obolibrary.org/obo/UPHENO_0047987
+http://purl.obolibrary.org/obo/UBERON_0001705	http://purl.obolibrary.org/obo/UPHENO_0047989
+http://purl.obolibrary.org/obo/UBERON_0000956	http://purl.obolibrary.org/obo/UPHENO_0047944
+http://purl.obolibrary.org/obo/UBERON_0001828	http://purl.obolibrary.org/obo/UPHENO_0079533
+http://purl.obolibrary.org/obo/UBERON_0001706	http://purl.obolibrary.org/obo/UPHENO_0047990
+http://purl.obolibrary.org/obo/UBERON_0000964	http://purl.obolibrary.org/obo/UPHENO_0047914
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+http://purl.obolibrary.org/obo/UBERON_0004769	http://purl.obolibrary.org/obo/UPHENO_0048001
+http://purl.obolibrary.org/obo/UBERON_0004528	http://purl.obolibrary.org/obo/UPHENO_0048002
+http://purl.obolibrary.org/obo/UBERON_0010163	http://purl.obolibrary.org/obo/UPHENO_0047975
+http://purl.obolibrary.org/obo/UBERON_0007709	http://purl.obolibrary.org/obo/UPHENO_0047976
+http://purl.obolibrary.org/obo/UBERON_0016422	http://purl.obolibrary.org/obo/UPHENO_0047977
diff --git a/src/curation/upheno-fillers/hp/abnormallyIncreasedThicknessOfAnatomicalEntityInLocation.tsv b/src/curation/upheno-fillers/hp/abnormallyIncreasedThicknessOfAnatomicalEntityInLocation.tsv
new file mode 100644
index 00000000..79c0b51e
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormallyIncreasedThicknessOfAnatomicalEntityInLocation.tsv
@@ -0,0 +1,5 @@
+anatomical_entity	location	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0016422	http://purl.obolibrary.org/obo/UPHENO_0048363
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0001021	http://purl.obolibrary.org/obo/UPHENO_0048358
+http://purl.obolibrary.org/obo/UBERON_0016423	http://purl.obolibrary.org/obo/UBERON_0016422	http://purl.obolibrary.org/obo/UPHENO_0048348
+http://purl.obolibrary.org/obo/UBERON_0000347	http://purl.obolibrary.org/obo/UBERON_0001021	http://purl.obolibrary.org/obo/UPHENO_0048356
diff --git a/src/curation/upheno-fillers/hp/abnormallyIncreasedVolumeOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/hp/abnormallyIncreasedVolumeOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..1a5f538f
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormallyIncreasedVolumeOfAnatomicalEntity.tsv
@@ -0,0 +1,5 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0084715
+http://purl.obolibrary.org/obo/UBERON_0001905	http://purl.obolibrary.org/obo/UPHENO_0084726
+http://purl.obolibrary.org/obo/CL_0000233	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0000004	http://purl.obolibrary.org/obo/UPHENO_0084727
diff --git a/src/curation/upheno-fillers/hp/abnormallyIncreasedWeightOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/hp/abnormallyIncreasedWeightOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..3677b7c8
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormallyIncreasedWeightOfAnatomicalEntity.tsv
@@ -0,0 +1,4 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0008273
+http://purl.obolibrary.org/obo/UBERON_0000468	http://purl.obolibrary.org/obo/UPHENO_0008312
+http://purl.obolibrary.org/obo/CL_0000764	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/hp/abnormallyIncreasedWidthOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/hp/abnormallyIncreasedWidthOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..f2098a7f
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormallyIncreasedWidthOfAnatomicalEntity.tsv
@@ -0,0 +1,112 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0008788	http://purl.obolibrary.org/obo/UPHENO_0006233
+http://purl.obolibrary.org/obo/UBERON_0004103	http://purl.obolibrary.org/obo/UPHENO_0006369
+http://purl.obolibrary.org/obo/UBERON_0003650	http://purl.obolibrary.org/obo/UPHENO_0006242
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0006161
+http://purl.obolibrary.org/obo/UBERON_0004330	http://purl.obolibrary.org/obo/UPHENO_0006371
+http://purl.obolibrary.org/obo/UBERON_0004331	http://purl.obolibrary.org/obo/UPHENO_0006372
+http://purl.obolibrary.org/obo/UBERON_0003645	http://purl.obolibrary.org/obo/UPHENO_0006246
+http://purl.obolibrary.org/obo/UBERON_0004338	http://purl.obolibrary.org/obo/UPHENO_0006373
+http://purl.obolibrary.org/obo/UBERON_0001466	http://purl.obolibrary.org/obo/UPHENO_0006247
+http://purl.obolibrary.org/obo/UBERON_0003129	http://purl.obolibrary.org/obo/UPHENO_0006374
+http://purl.obolibrary.org/obo/UBERON_0001105	http://purl.obolibrary.org/obo/UPHENO_0006248
+http://purl.obolibrary.org/obo/UBERON_0004336	http://purl.obolibrary.org/obo/UPHENO_0006375
+http://purl.obolibrary.org/obo/UBERON_0003126	http://purl.obolibrary.org/obo/UPHENO_0006376
+http://purl.obolibrary.org/obo/UBERON_0004337	http://purl.obolibrary.org/obo/UPHENO_0006377
+http://purl.obolibrary.org/obo/UBERON_0003641	http://purl.obolibrary.org/obo/UPHENO_0006249
+http://purl.obolibrary.org/obo/UBERON_0004334	http://purl.obolibrary.org/obo/UPHENO_0006378
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+http://purl.obolibrary.org/obo/UBERON_0004335	http://purl.obolibrary.org/obo/UPHENO_0006379
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+http://purl.obolibrary.org/obo/UBERON_0001734	http://purl.obolibrary.org/obo/UPHENO_0006382
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+http://purl.obolibrary.org/obo/UBERON_0002389	http://purl.obolibrary.org/obo/UPHENO_0006390
+http://purl.obolibrary.org/obo/UBERON_0004328	http://purl.obolibrary.org/obo/UPHENO_0006391
+http://purl.obolibrary.org/obo/UBERON_0003632	http://purl.obolibrary.org/obo/UPHENO_0006268
+http://purl.obolibrary.org/obo/UBERON_0004325	http://purl.obolibrary.org/obo/UPHENO_0006394
+http://purl.obolibrary.org/obo/UBERON_0000004	http://purl.obolibrary.org/obo/UPHENO_0006269
+http://purl.obolibrary.org/obo/UBERON_0003633	http://purl.obolibrary.org/obo/UPHENO_0006270
+http://purl.obolibrary.org/obo/UBERON_0001456	http://purl.obolibrary.org/obo/UPHENO_0006186
+http://purl.obolibrary.org/obo/UBERON_0004326	http://purl.obolibrary.org/obo/UPHENO_0006395
+http://purl.obolibrary.org/obo/UBERON_0004323	http://purl.obolibrary.org/obo/UPHENO_0006398
+http://purl.obolibrary.org/obo/UBERON_0006865	http://purl.obolibrary.org/obo/UPHENO_0006397
+http://purl.obolibrary.org/obo/UBERON_0003631	http://purl.obolibrary.org/obo/UPHENO_0006271
+http://purl.obolibrary.org/obo/UBERON_0004324	http://purl.obolibrary.org/obo/UPHENO_0006399
+http://purl.obolibrary.org/obo/UBERON_0006864	http://purl.obolibrary.org/obo/UPHENO_0006400
+http://purl.obolibrary.org/obo/UBERON_0004321	http://purl.obolibrary.org/obo/UPHENO_0006401
+http://purl.obolibrary.org/obo/UBERON_0006863	http://purl.obolibrary.org/obo/UPHENO_0006402
+http://purl.obolibrary.org/obo/UBERON_0002387	http://purl.obolibrary.org/obo/UPHENO_0006403
+http://purl.obolibrary.org/obo/UBERON_0004322	http://purl.obolibrary.org/obo/UPHENO_0006404
+http://purl.obolibrary.org/obo/UBERON_0005928	http://purl.obolibrary.org/obo/UPHENO_0006274
+http://purl.obolibrary.org/obo/UBERON_0001448	http://purl.obolibrary.org/obo/UPHENO_0006276
+http://purl.obolibrary.org/obo/UBERON_0004318	http://purl.obolibrary.org/obo/UPHENO_0006408
+http://purl.obolibrary.org/obo/UBERON_0003867	http://purl.obolibrary.org/obo/UPHENO_0006278
+http://purl.obolibrary.org/obo/UBERON_0004319	http://purl.obolibrary.org/obo/UPHENO_0006409
+http://purl.obolibrary.org/obo/UBERON_0001449	http://purl.obolibrary.org/obo/UPHENO_0006279
+http://purl.obolibrary.org/obo/UBERON_0003868	http://purl.obolibrary.org/obo/UPHENO_0006280
+http://purl.obolibrary.org/obo/UBERON_0016425	http://purl.obolibrary.org/obo/UPHENO_0006411
+http://purl.obolibrary.org/obo/UBERON_0010163	http://purl.obolibrary.org/obo/UPHENO_0006283
+http://purl.obolibrary.org/obo/UBERON_0008878	http://purl.obolibrary.org/obo/UPHENO_0006284
+http://purl.obolibrary.org/obo/UBERON_0004390	http://purl.obolibrary.org/obo/UPHENO_0006287
+http://purl.obolibrary.org/obo/UBERON_0003865	http://purl.obolibrary.org/obo/UPHENO_0006288
+http://purl.obolibrary.org/obo/UBERON_0004316	http://purl.obolibrary.org/obo/UPHENO_0006424
+http://purl.obolibrary.org/obo/UBERON_0004317	http://purl.obolibrary.org/obo/UPHENO_0006425
+http://purl.obolibrary.org/obo/UBERON_0003866	http://purl.obolibrary.org/obo/UPHENO_0006289
+http://purl.obolibrary.org/obo/UBERON_0004314	http://purl.obolibrary.org/obo/UPHENO_0006426
+http://purl.obolibrary.org/obo/UBERON_0003863	http://purl.obolibrary.org/obo/UPHENO_0006290
+http://purl.obolibrary.org/obo/UBERON_0001446	http://purl.obolibrary.org/obo/UPHENO_0006291
+http://purl.obolibrary.org/obo/UBERON_0004315	http://purl.obolibrary.org/obo/UPHENO_0006428
+http://purl.obolibrary.org/obo/UBERON_0003864	http://purl.obolibrary.org/obo/UPHENO_0006292
+http://purl.obolibrary.org/obo/UBERON_0004312	http://purl.obolibrary.org/obo/UPHENO_0006429
+http://purl.obolibrary.org/obo/UBERON_0005402	http://purl.obolibrary.org/obo/UPHENO_0006431
+http://purl.obolibrary.org/obo/UBERON_0004313	http://purl.obolibrary.org/obo/UPHENO_0006433
+http://purl.obolibrary.org/obo/UBERON_0002495	http://purl.obolibrary.org/obo/UPHENO_0006221
+http://purl.obolibrary.org/obo/UBERON_0002374	http://purl.obolibrary.org/obo/UPHENO_0006432
+http://purl.obolibrary.org/obo/UBERON_0003862	http://purl.obolibrary.org/obo/UPHENO_0006293
+http://purl.obolibrary.org/obo/UBERON_0003221	http://purl.obolibrary.org/obo/UPHENO_0006436
+http://purl.obolibrary.org/obo/UBERON_0004311	http://purl.obolibrary.org/obo/UPHENO_0006438
+http://purl.obolibrary.org/obo/UBERON_0001436	http://purl.obolibrary.org/obo/UPHENO_0006299
+http://purl.obolibrary.org/obo/UBERON_0001438	http://purl.obolibrary.org/obo/UPHENO_0006300
+http://purl.obolibrary.org/obo/UBERON_0004382	http://purl.obolibrary.org/obo/UPHENO_0006305
+http://purl.obolibrary.org/obo/UBERON_0001433	http://purl.obolibrary.org/obo/UPHENO_0006307
+http://purl.obolibrary.org/obo/UBERON_0008340	http://purl.obolibrary.org/obo/UPHENO_0006147
+http://purl.obolibrary.org/obo/UBERON_0001435	http://purl.obolibrary.org/obo/UPHENO_0006309
+http://purl.obolibrary.org/obo/UBERON_0009552	http://purl.obolibrary.org/obo/UPHENO_0006447
+http://purl.obolibrary.org/obo/UBERON_0003699	http://purl.obolibrary.org/obo/UPHENO_0006448
+http://purl.obolibrary.org/obo/UBERON_0001274	http://purl.obolibrary.org/obo/UPHENO_0006450
+http://purl.obolibrary.org/obo/UBERON_0001705	http://purl.obolibrary.org/obo/UPHENO_0006456
+http://purl.obolibrary.org/obo/UBERON_0000974	http://purl.obolibrary.org/obo/UPHENO_0006457
+http://purl.obolibrary.org/obo/UBERON_0000976	http://purl.obolibrary.org/obo/UPHENO_0006459
+http://purl.obolibrary.org/obo/UBERON_0002510	http://purl.obolibrary.org/obo/UPHENO_0006330
+http://purl.obolibrary.org/obo/UBERON_0001424	http://purl.obolibrary.org/obo/UPHENO_0006331
+http://purl.obolibrary.org/obo/UBERON_0001423	http://purl.obolibrary.org/obo/UPHENO_0006332
+http://purl.obolibrary.org/obo/UBERON_0003685	http://purl.obolibrary.org/obo/UPHENO_0006166
+http://purl.obolibrary.org/obo/UBERON_0004412	http://purl.obolibrary.org/obo/UPHENO_0006461
+http://purl.obolibrary.org/obo/UBERON_0002234	http://purl.obolibrary.org/obo/UPHENO_0006462
+http://purl.obolibrary.org/obo/UBERON_0004652	http://purl.obolibrary.org/obo/UPHENO_0006463
+http://purl.obolibrary.org/obo/UBERON_0002228	http://purl.obolibrary.org/obo/UPHENO_0006170
+http://purl.obolibrary.org/obo/UBERON_0004527	http://purl.obolibrary.org/obo/UPHENO_0006467
+http://purl.obolibrary.org/obo/UBERON_0002185	http://purl.obolibrary.org/obo/UPHENO_0006349
+http://purl.obolibrary.org/obo/UBERON_0013748	http://purl.obolibrary.org/obo/UPHENO_0006351
+http://purl.obolibrary.org/obo/UBERON_0007119	http://purl.obolibrary.org/obo/UPHENO_0006187
+http://purl.obolibrary.org/obo/UBERON_0008200	http://purl.obolibrary.org/obo/UPHENO_0006473
+http://purl.obolibrary.org/obo/UBERON_0000165	http://purl.obolibrary.org/obo/UPHENO_0006476
+http://purl.obolibrary.org/obo/UBERON_0001528	http://purl.obolibrary.org/obo/UPHENO_0006356
+http://purl.obolibrary.org/obo/UBERON_0000315	http://purl.obolibrary.org/obo/UPHENO_0082558
+http://purl.obolibrary.org/obo/UBERON_0013753	http://purl.obolibrary.org/obo/UPHENO_0006357
+http://purl.obolibrary.org/obo/UBERON_0013750	http://purl.obolibrary.org/obo/UPHENO_0006359
+http://purl.obolibrary.org/obo/UBERON_0013751	http://purl.obolibrary.org/obo/UPHENO_0006361
+http://purl.obolibrary.org/obo/UBERON_0012128	http://purl.obolibrary.org/obo/UPHENO_0006479
+http://purl.obolibrary.org/obo/UBERON_0002207	http://purl.obolibrary.org/obo/UPHENO_0006484
diff --git a/src/curation/upheno-fillers/hp/abnormallyIncreasedWidthOfAnatomicalEntityInLocation.tsv b/src/curation/upheno-fillers/hp/abnormallyIncreasedWidthOfAnatomicalEntityInLocation.tsv
new file mode 100644
index 00000000..560054f3
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormallyIncreasedWidthOfAnatomicalEntityInLocation.tsv
@@ -0,0 +1,10 @@
+anatomical_entity	location	defined_class
+http://purl.obolibrary.org/obo/UBERON_0002516	http://purl.obolibrary.org/obo/UBERON_0000976	http://purl.obolibrary.org/obo/UPHENO_0081796
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0010708	http://purl.obolibrary.org/obo/UPHENO_0081801
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0000976	http://purl.obolibrary.org/obo/UPHENO_0081802
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0001130	http://purl.obolibrary.org/obo/UPHENO_0081804
+http://purl.obolibrary.org/obo/UBERON_0004769	http://purl.obolibrary.org/obo/UBERON_0010708	http://purl.obolibrary.org/obo/UPHENO_0081805
+http://purl.obolibrary.org/obo/UBERON_0001437	http://purl.obolibrary.org/obo/UBERON_0010708	http://purl.obolibrary.org/obo/UPHENO_0081806
+http://purl.obolibrary.org/obo/UBERON_0001438	http://purl.obolibrary.org/obo/UBERON_0010708	http://purl.obolibrary.org/obo/UPHENO_0081807
+http://purl.obolibrary.org/obo/UBERON_0002516	http://purl.obolibrary.org/obo/UBERON_0010708	http://purl.obolibrary.org/obo/UPHENO_0081808
+http://purl.obolibrary.org/obo/UBERON_0006692	http://purl.obolibrary.org/obo/UBERON_0001130	http://purl.obolibrary.org/obo/UPHENO_0081809
diff --git a/src/curation/upheno-fillers/hp/abnormallyOpaqueAnatomicalEntity.tsv b/src/curation/upheno-fillers/hp/abnormallyOpaqueAnatomicalEntity.tsv
new file mode 100644
index 00000000..a0be4102
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormallyOpaqueAnatomicalEntity.tsv
@@ -0,0 +1,4 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0000965	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0016459	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/hp/abnormallyOpenAnatomicalEntity.tsv b/src/curation/upheno-fillers/hp/abnormallyOpenAnatomicalEntity.tsv
new file mode 100644
index 00000000..aa4c0567
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormallyOpenAnatomicalEntity.tsv
@@ -0,0 +1,5 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0075655
+http://purl.obolibrary.org/obo/UBERON_0002492	http://purl.obolibrary.org/obo/UPHENO_0075660
+http://purl.obolibrary.org/obo/UBERON_0002489	http://purl.obolibrary.org/obo/UPHENO_0075661
+http://purl.obolibrary.org/obo/UBERON_0000165	http://purl.obolibrary.org/obo/UPHENO_0075662
diff --git a/src/curation/upheno-fillers/hp/abnormallyPrematureBiologicalProcess.tsv b/src/curation/upheno-fillers/hp/abnormallyPrematureBiologicalProcess.tsv
new file mode 100644
index 00000000..7d55b92d
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormallyPrematureBiologicalProcess.tsv
@@ -0,0 +1,10 @@
+biological_process	defined_class
+http://purl.obolibrary.org/obo/GO_0000819	http://purl.obolibrary.org/obo/UPHENO_0049454
+http://purl.obolibrary.org/obo/GO_0007567	http://purl.obolibrary.org/obo/UPHENO_0049449
+http://purl.obolibrary.org/obo/GO_0042713	http://purl.obolibrary.org/obo/UPHENO_0080420
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UPHENO_0049440
+http://purl.obolibrary.org/obo/GO_0046543	http://purl.obolibrary.org/obo/UPHENO_0049458
+http://purl.obolibrary.org/obo/GO_0030261	http://purl.obolibrary.org/obo/UPHENO_0049455
+http://purl.obolibrary.org/obo/GO_0042695	http://purl.obolibrary.org/obo/UPHENO_0049452
+http://purl.obolibrary.org/obo/GO_0046544	http://purl.obolibrary.org/obo/UPHENO_0049461
+http://purl.obolibrary.org/obo/GO_0045136	http://purl.obolibrary.org/obo/UPHENO_0049462
diff --git a/src/curation/upheno-fillers/hp/abnormallyPrematureBiologicalProcessInLocation.tsv b/src/curation/upheno-fillers/hp/abnormallyPrematureBiologicalProcessInLocation.tsv
new file mode 100644
index 00000000..c9acfed2
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormallyPrematureBiologicalProcessInLocation.tsv
@@ -0,0 +1,13 @@
+biological_process	location	defined_class
+http://purl.obolibrary.org/obo/GO_0001503	http://purl.obolibrary.org/obo/UBERON_0002293	http://purl.obolibrary.org/obo/UPHENO_0083709
+http://purl.obolibrary.org/obo/GO_0001503	http://purl.obolibrary.org/obo/UBERON_0004382	http://purl.obolibrary.org/obo/UPHENO_0083711
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0001447	http://purl.obolibrary.org/obo/UPHENO_0083712
+http://purl.obolibrary.org/obo/GO_0001503	http://purl.obolibrary.org/obo/UBERON_0001435	http://purl.obolibrary.org/obo/UPHENO_0083713
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0002293	http://purl.obolibrary.org/obo/UPHENO_0083714
+http://purl.obolibrary.org/obo/GO_0001503	http://purl.obolibrary.org/obo/UBERON_0001442	http://purl.obolibrary.org/obo/UPHENO_0083715
+http://purl.obolibrary.org/obo/GO_0001503	http://purl.obolibrary.org/obo/UBERON_0004412	http://purl.obolibrary.org/obo/UPHENO_0083716
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0001435	http://purl.obolibrary.org/obo/UPHENO_0083717
+http://purl.obolibrary.org/obo/GO_0001503	http://purl.obolibrary.org/obo/UBERON_0001447	http://purl.obolibrary.org/obo/UPHENO_0083719
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0004382	http://purl.obolibrary.org/obo/UPHENO_0083720
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0001442	http://purl.obolibrary.org/obo/UPHENO_0083721
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0004412	http://purl.obolibrary.org/obo/UPHENO_0083722
diff --git a/src/curation/upheno-fillers/hp/abnormallyProminentAnatomicalEntity.tsv b/src/curation/upheno-fillers/hp/abnormallyProminentAnatomicalEntity.tsv
new file mode 100644
index 00000000..12e2c62a
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormallyProminentAnatomicalEntity.tsv
@@ -0,0 +1,38 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0004089	http://purl.obolibrary.org/obo/UPHENO_0082907
+http://purl.obolibrary.org/obo/UBERON_0001350	http://purl.obolibrary.org/obo/UPHENO_0082908
+http://purl.obolibrary.org/obo/UBERON_0002500	http://purl.obolibrary.org/obo/UPHENO_0082909
+http://purl.obolibrary.org/obo/UBERON_0002488	http://purl.obolibrary.org/obo/UPHENO_0082910
+http://purl.obolibrary.org/obo/UBERON_0008340	http://purl.obolibrary.org/obo/UPHENO_0082903
+http://purl.obolibrary.org/obo/UBERON_0000004	http://purl.obolibrary.org/obo/UPHENO_0082911
+http://purl.obolibrary.org/obo/UBERON_0004106	http://purl.obolibrary.org/obo/UPHENO_0082912
+http://purl.obolibrary.org/obo/UBERON_0009552	http://purl.obolibrary.org/obo/UPHENO_0082913
+http://purl.obolibrary.org/obo/UBERON_0001676	http://purl.obolibrary.org/obo/UPHENO_0082914
+http://purl.obolibrary.org/obo/UBERON_0008200	http://purl.obolibrary.org/obo/UPHENO_0082905
+http://purl.obolibrary.org/obo/UBERON_0007118	http://purl.obolibrary.org/obo/UPHENO_0082915
+http://purl.obolibrary.org/obo/UBERON_0001450	http://purl.obolibrary.org/obo/UPHENO_0082916
+http://purl.obolibrary.org/obo/UBERON_0002244	http://purl.obolibrary.org/obo/UPHENO_0082917
+http://purl.obolibrary.org/obo/UBERON_0016440	http://purl.obolibrary.org/obo/UPHENO_0082918
+http://purl.obolibrary.org/obo/UBERON_0001706	http://purl.obolibrary.org/obo/UPHENO_0082919
+http://purl.obolibrary.org/obo/UBERON_0002239	http://purl.obolibrary.org/obo/UPHENO_0082920
+http://purl.obolibrary.org/obo/UBERON_0000975	http://purl.obolibrary.org/obo/UPHENO_0082921
+http://purl.obolibrary.org/obo/UBERON_0016466	http://purl.obolibrary.org/obo/UPHENO_0082922
+http://purl.obolibrary.org/obo/UBERON_0017732	http://purl.obolibrary.org/obo/UPHENO_0082923
+http://purl.obolibrary.org/obo/UBERON_0011575	http://purl.obolibrary.org/obo/UPHENO_0082924
+http://purl.obolibrary.org/obo/UBERON_0016467	http://purl.obolibrary.org/obo/UPHENO_0082925
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0082900
+http://purl.obolibrary.org/obo/UBERON_0002030	http://purl.obolibrary.org/obo/UPHENO_0082926
+http://purl.obolibrary.org/obo/UBERON_0010887	http://purl.obolibrary.org/obo/UPHENO_0082927
+http://purl.obolibrary.org/obo/UBERON_0009767	http://purl.obolibrary.org/obo/UPHENO_0082928
+http://purl.obolibrary.org/obo/UBERON_0012128	http://purl.obolibrary.org/obo/UPHENO_0082929
+http://purl.obolibrary.org/obo/UBERON_0002490	http://purl.obolibrary.org/obo/UPHENO_0082930
+http://purl.obolibrary.org/obo/UBERON_0006658	http://purl.obolibrary.org/obo/UPHENO_0082931
+http://purl.obolibrary.org/obo/UBERON_0001684	http://purl.obolibrary.org/obo/UPHENO_0082906
+http://purl.obolibrary.org/obo/UBERON_0002498	http://purl.obolibrary.org/obo/UPHENO_0082932
+http://purl.obolibrary.org/obo/UBERON_0000210	http://purl.obolibrary.org/obo/UPHENO_0082933
+http://purl.obolibrary.org/obo/UBERON_0001683	http://purl.obolibrary.org/obo/UPHENO_0082934
+http://purl.obolibrary.org/obo/UBERON_0019246	http://purl.obolibrary.org/obo/UPHENO_0082935
+http://purl.obolibrary.org/obo/UBERON_0002207	http://purl.obolibrary.org/obo/UPHENO_0082936
+http://purl.obolibrary.org/obo/UBERON_0001835	http://purl.obolibrary.org/obo/UPHENO_0082937
+http://purl.obolibrary.org/obo/UBERON_0001834	http://purl.obolibrary.org/obo/UPHENO_0082938
+http://purl.obolibrary.org/obo/UBERON_0035550	http://purl.obolibrary.org/obo/UPHENO_0082939
diff --git a/src/curation/upheno-fillers/hp/abnormallyProtrudingAnatomicalEntity.tsv b/src/curation/upheno-fillers/hp/abnormallyProtrudingAnatomicalEntity.tsv
new file mode 100644
index 00000000..36d0666a
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormallyProtrudingAnatomicalEntity.tsv
@@ -0,0 +1,9 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002293	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001350	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001691	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001723	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0000975	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0010230	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001269	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/hp/abnormallyProtrudingAnatomicalEntityInLocation.tsv b/src/curation/upheno-fillers/hp/abnormallyProtrudingAnatomicalEntityInLocation.tsv
new file mode 100644
index 00000000..5f739701
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormallyProtrudingAnatomicalEntityInLocation.tsv
@@ -0,0 +1,3 @@
+anatomical_entity	location	defined_class
+http://purl.obolibrary.org/obo/UBERON_0002360	http://purl.obolibrary.org/obo/UBERON_0003129	http://purl.obolibrary.org/obo/UPHENO_0024968
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0003129	http://purl.obolibrary.org/obo/UPHENO_0024973
diff --git a/src/curation/upheno-fillers/hp/abnormallyPunctateAnatomicalEntity.tsv b/src/curation/upheno-fillers/hp/abnormallyPunctateAnatomicalEntity.tsv
new file mode 100644
index 00000000..8696ac79
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormallyPunctateAnatomicalEntity.tsv
@@ -0,0 +1,8 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0084708
+http://purl.obolibrary.org/obo/UBERON_0004395	http://purl.obolibrary.org/obo/UPHENO_0084709
+http://purl.obolibrary.org/obo/UBERON_0001437	http://purl.obolibrary.org/obo/UPHENO_0084710
+http://purl.obolibrary.org/obo/UBERON_0004382	http://purl.obolibrary.org/obo/UPHENO_0084711
+http://purl.obolibrary.org/obo/UBERON_0004390	http://purl.obolibrary.org/obo/UPHENO_0084712
+http://purl.obolibrary.org/obo/UBERON_0004391	http://purl.obolibrary.org/obo/UPHENO_0084713
+http://purl.obolibrary.org/obo/UBERON_0004387	http://purl.obolibrary.org/obo/UPHENO_0084714
diff --git a/src/curation/upheno-fillers/hp/abnormallyPunctateAnatomicalEntityInLocation.tsv b/src/curation/upheno-fillers/hp/abnormallyPunctateAnatomicalEntityInLocation.tsv
new file mode 100644
index 00000000..49d3d6c7
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormallyPunctateAnatomicalEntityInLocation.tsv
@@ -0,0 +1,85 @@
+anatomical_entity	location	defined_class
+http://purl.obolibrary.org/obo/UBERON_0004387	http://purl.obolibrary.org/obo/UBERON_0003865	http://purl.obolibrary.org/obo/UPHENO_0084544
+http://purl.obolibrary.org/obo/UBERON_0004387	http://purl.obolibrary.org/obo/UBERON_0004311	http://purl.obolibrary.org/obo/UPHENO_0084545
+http://purl.obolibrary.org/obo/UBERON_0004387	http://purl.obolibrary.org/obo/UBERON_0004314	http://purl.obolibrary.org/obo/UPHENO_0084546
+http://purl.obolibrary.org/obo/UBERON_0004387	http://purl.obolibrary.org/obo/UBERON_0004312	http://purl.obolibrary.org/obo/UPHENO_0084547
+http://purl.obolibrary.org/obo/UBERON_0004387	http://purl.obolibrary.org/obo/UBERON_0003620	http://purl.obolibrary.org/obo/UPHENO_0084548
+http://purl.obolibrary.org/obo/UBERON_0004387	http://purl.obolibrary.org/obo/UBERON_0004313	http://purl.obolibrary.org/obo/UPHENO_0084549
+http://purl.obolibrary.org/obo/UBERON_0001437	http://purl.obolibrary.org/obo/UBERON_0004336	http://purl.obolibrary.org/obo/UPHENO_0084551
+http://purl.obolibrary.org/obo/UBERON_0001437	http://purl.obolibrary.org/obo/UBERON_0004332	http://purl.obolibrary.org/obo/UPHENO_0084552
+http://purl.obolibrary.org/obo/UBERON_0001437	http://purl.obolibrary.org/obo/UBERON_0003640	http://purl.obolibrary.org/obo/UPHENO_0084553
+http://purl.obolibrary.org/obo/UBERON_0001437	http://purl.obolibrary.org/obo/UBERON_0004333	http://purl.obolibrary.org/obo/UPHENO_0084554
+http://purl.obolibrary.org/obo/UBERON_0004387	http://purl.obolibrary.org/obo/UBERON_0003864	http://purl.obolibrary.org/obo/UPHENO_0084555
+http://purl.obolibrary.org/obo/UBERON_0001437	http://purl.obolibrary.org/obo/UBERON_0004334	http://purl.obolibrary.org/obo/UPHENO_0084556
+http://purl.obolibrary.org/obo/UBERON_0001437	http://purl.obolibrary.org/obo/UBERON_0004335	http://purl.obolibrary.org/obo/UPHENO_0084557
+http://purl.obolibrary.org/obo/UBERON_0001437	http://purl.obolibrary.org/obo/UBERON_0004318	http://purl.obolibrary.org/obo/UPHENO_0084558
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0004336	http://purl.obolibrary.org/obo/UPHENO_0084559
+http://purl.obolibrary.org/obo/UBERON_0001437	http://purl.obolibrary.org/obo/UBERON_0001449	http://purl.obolibrary.org/obo/UPHENO_0084560
+http://purl.obolibrary.org/obo/UBERON_0001437	http://purl.obolibrary.org/obo/UBERON_0004319	http://purl.obolibrary.org/obo/UPHENO_0084561
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0004337	http://purl.obolibrary.org/obo/UPHENO_0084562
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0004332	http://purl.obolibrary.org/obo/UPHENO_0084563
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0003640	http://purl.obolibrary.org/obo/UPHENO_0084564
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0004333	http://purl.obolibrary.org/obo/UPHENO_0084565
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0004338	http://purl.obolibrary.org/obo/UPHENO_0084567
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0004334	http://purl.obolibrary.org/obo/UPHENO_0084568
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0004335	http://purl.obolibrary.org/obo/UPHENO_0084569
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0003636	http://purl.obolibrary.org/obo/UPHENO_0084570
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0002234	http://purl.obolibrary.org/obo/UPHENO_0084571
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0004329	http://purl.obolibrary.org/obo/UPHENO_0084572
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0003637	http://purl.obolibrary.org/obo/UPHENO_0084573
+http://purl.obolibrary.org/obo/UBERON_0001437	http://purl.obolibrary.org/obo/UBERON_0003632	http://purl.obolibrary.org/obo/UPHENO_0084574
+http://purl.obolibrary.org/obo/UBERON_0001437	http://purl.obolibrary.org/obo/UBERON_0004325	http://purl.obolibrary.org/obo/UPHENO_0084575
+http://purl.obolibrary.org/obo/UBERON_0001437	http://purl.obolibrary.org/obo/UBERON_0003633	http://purl.obolibrary.org/obo/UPHENO_0084576
+http://purl.obolibrary.org/obo/UBERON_0001437	http://purl.obolibrary.org/obo/UBERON_0004326	http://purl.obolibrary.org/obo/UPHENO_0084577
+http://purl.obolibrary.org/obo/UBERON_0001437	http://purl.obolibrary.org/obo/UBERON_0003634	http://purl.obolibrary.org/obo/UPHENO_0084578
+http://purl.obolibrary.org/obo/UBERON_0001437	http://purl.obolibrary.org/obo/UBERON_0004327	http://purl.obolibrary.org/obo/UPHENO_0084579
+http://purl.obolibrary.org/obo/UBERON_0001437	http://purl.obolibrary.org/obo/UBERON_0003635	http://purl.obolibrary.org/obo/UPHENO_0084580
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0004330	http://purl.obolibrary.org/obo/UPHENO_0084581
+http://purl.obolibrary.org/obo/UBERON_0001437	http://purl.obolibrary.org/obo/UBERON_0004324	http://purl.obolibrary.org/obo/UPHENO_0084582
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0004331	http://purl.obolibrary.org/obo/UPHENO_0084583
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0003632	http://purl.obolibrary.org/obo/UPHENO_0084584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0004325	http://purl.obolibrary.org/obo/UPHENO_0084585
+http://purl.obolibrary.org/obo/UBERON_0004387	http://purl.obolibrary.org/obo/UBERON_0004338	http://purl.obolibrary.org/obo/UPHENO_0084586
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0003633	http://purl.obolibrary.org/obo/UPHENO_0084587
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0004326	http://purl.obolibrary.org/obo/UPHENO_0084588
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0004321	http://purl.obolibrary.org/obo/UPHENO_0084589
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0004322	http://purl.obolibrary.org/obo/UPHENO_0084590
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0003634	http://purl.obolibrary.org/obo/UPHENO_0084591
+http://purl.obolibrary.org/obo/UBERON_0004387	http://purl.obolibrary.org/obo/UBERON_0002234	http://purl.obolibrary.org/obo/UPHENO_0084592
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0004327	http://purl.obolibrary.org/obo/UPHENO_0084593
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0003635	http://purl.obolibrary.org/obo/UPHENO_0084594
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0004328	http://purl.obolibrary.org/obo/UPHENO_0084595
+http://purl.obolibrary.org/obo/UBERON_0004387	http://purl.obolibrary.org/obo/UBERON_0003637	http://purl.obolibrary.org/obo/UPHENO_0084596
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0004323	http://purl.obolibrary.org/obo/UPHENO_0084597
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0004324	http://purl.obolibrary.org/obo/UPHENO_0084598
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0004318	http://purl.obolibrary.org/obo/UPHENO_0084599
+http://purl.obolibrary.org/obo/UBERON_0004387	http://purl.obolibrary.org/obo/UBERON_0003638	http://purl.obolibrary.org/obo/UPHENO_0084600
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0004319	http://purl.obolibrary.org/obo/UPHENO_0084601
+http://purl.obolibrary.org/obo/UBERON_0004387	http://purl.obolibrary.org/obo/UBERON_0003639	http://purl.obolibrary.org/obo/UPHENO_0084602
+http://purl.obolibrary.org/obo/UBERON_0004387	http://purl.obolibrary.org/obo/UBERON_0004329	http://purl.obolibrary.org/obo/UPHENO_0084603
+http://purl.obolibrary.org/obo/UBERON_0004387	http://purl.obolibrary.org/obo/UBERON_0003636	http://purl.obolibrary.org/obo/UPHENO_0084604
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0003638	http://purl.obolibrary.org/obo/UPHENO_0084605
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0003639	http://purl.obolibrary.org/obo/UPHENO_0084606
+http://purl.obolibrary.org/obo/UBERON_0001437	http://purl.obolibrary.org/obo/UBERON_0004315	http://purl.obolibrary.org/obo/UPHENO_0084607
+http://purl.obolibrary.org/obo/UBERON_0004387	http://purl.obolibrary.org/obo/UBERON_0004330	http://purl.obolibrary.org/obo/UPHENO_0084608
+http://purl.obolibrary.org/obo/UBERON_0001437	http://purl.obolibrary.org/obo/UBERON_0004316	http://purl.obolibrary.org/obo/UPHENO_0084609
+http://purl.obolibrary.org/obo/UBERON_0001437	http://purl.obolibrary.org/obo/UBERON_0004317	http://purl.obolibrary.org/obo/UPHENO_0084610
+http://purl.obolibrary.org/obo/UBERON_0004387	http://purl.obolibrary.org/obo/UBERON_0004331	http://purl.obolibrary.org/obo/UPHENO_0084611
+http://purl.obolibrary.org/obo/UBERON_0004387	http://purl.obolibrary.org/obo/UBERON_0004337	http://purl.obolibrary.org/obo/UPHENO_0084612
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0004320	http://purl.obolibrary.org/obo/UPHENO_0084613
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0004314	http://purl.obolibrary.org/obo/UPHENO_0084614
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0003864	http://purl.obolibrary.org/obo/UPHENO_0084615
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0004315	http://purl.obolibrary.org/obo/UPHENO_0084616
+http://purl.obolibrary.org/obo/UBERON_0004387	http://purl.obolibrary.org/obo/UBERON_0004322	http://purl.obolibrary.org/obo/UPHENO_0084617
+http://purl.obolibrary.org/obo/UBERON_0004387	http://purl.obolibrary.org/obo/UBERON_0004328	http://purl.obolibrary.org/obo/UPHENO_0084618
+http://purl.obolibrary.org/obo/UBERON_0004387	http://purl.obolibrary.org/obo/UBERON_0004323	http://purl.obolibrary.org/obo/UPHENO_0084619
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0004311	http://purl.obolibrary.org/obo/UPHENO_0084620
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0003865	http://purl.obolibrary.org/obo/UPHENO_0084621
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0004316	http://purl.obolibrary.org/obo/UPHENO_0084622
+http://purl.obolibrary.org/obo/UBERON_0004387	http://purl.obolibrary.org/obo/UBERON_0004321	http://purl.obolibrary.org/obo/UPHENO_0084623
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0004317	http://purl.obolibrary.org/obo/UPHENO_0084624
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0004312	http://purl.obolibrary.org/obo/UPHENO_0084626
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0004313	http://purl.obolibrary.org/obo/UPHENO_0084627
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0003620	http://purl.obolibrary.org/obo/UPHENO_0084628
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0001449	http://purl.obolibrary.org/obo/UPHENO_0084629
+http://purl.obolibrary.org/obo/UBERON_0004387	http://purl.obolibrary.org/obo/UBERON_0004320	http://purl.obolibrary.org/obo/UPHENO_0084630
diff --git a/src/curation/upheno-fillers/hp/abnormallyRotatedAnatomicalEntity.tsv b/src/curation/upheno-fillers/hp/abnormallyRotatedAnatomicalEntity.tsv
new file mode 100644
index 00000000..cf2227d2
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abnormallyRotatedAnatomicalEntity.tsv
@@ -0,0 +1,7 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0082022
+http://purl.obolibrary.org/obo/UBERON_0002108	http://purl.obolibrary.org/obo/UPHENO_0082024
+http://purl.obolibrary.org/obo/UBERON_0005409	http://purl.obolibrary.org/obo/UPHENO_0082025
+http://purl.obolibrary.org/obo/UBERON_0002113	http://purl.obolibrary.org/obo/UPHENO_0082026
+http://purl.obolibrary.org/obo/UBERON_0001155	http://purl.obolibrary.org/obo/UPHENO_0082027
+http://purl.obolibrary.org/obo/UBERON_0001045	http://purl.obolibrary.org/obo/UPHENO_0082028
diff --git a/src/curation/upheno-fillers/hp/abscessInLocation.tsv b/src/curation/upheno-fillers/hp/abscessInLocation.tsv
new file mode 100644
index 00000000..7761b469
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/abscessInLocation.tsv
@@ -0,0 +1 @@
+abscess	anatomical_entity	defined_class
diff --git a/src/curation/upheno-fillers/hp/aplasticAnatomicalEntity.tsv b/src/curation/upheno-fillers/hp/aplasticAnatomicalEntity.tsv
new file mode 100644
index 00000000..95c3f14c
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/aplasticAnatomicalEntity.tsv
@@ -0,0 +1,102 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0003654	http://purl.obolibrary.org/obo/UPHENO_0081442
+http://purl.obolibrary.org/obo/UBERON_0001473	http://purl.obolibrary.org/obo/UPHENO_0081443
+http://purl.obolibrary.org/obo/UBERON_0003650	http://purl.obolibrary.org/obo/UPHENO_0081444
+http://purl.obolibrary.org/obo/UBERON_0001507	http://purl.obolibrary.org/obo/UPHENO_0081445
+http://purl.obolibrary.org/obo/UBERON_0001905	http://purl.obolibrary.org/obo/UPHENO_0081446
+http://purl.obolibrary.org/obo/UBERON_0003649	http://purl.obolibrary.org/obo/UPHENO_0081447
+http://purl.obolibrary.org/obo/UBERON_0003647	http://purl.obolibrary.org/obo/UPHENO_0081448
+http://purl.obolibrary.org/obo/UBERON_0003889	http://purl.obolibrary.org/obo/UPHENO_0081449
+http://purl.obolibrary.org/obo/UBERON_0003648	http://purl.obolibrary.org/obo/UPHENO_0081450
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0081451
+http://purl.obolibrary.org/obo/UBERON_0004330	http://purl.obolibrary.org/obo/UPHENO_0081452
+http://purl.obolibrary.org/obo/UBERON_0004331	http://purl.obolibrary.org/obo/UPHENO_0081453
+http://purl.obolibrary.org/obo/UBERON_0004338	http://purl.obolibrary.org/obo/UPHENO_0081454
+http://purl.obolibrary.org/obo/UBERON_0003645	http://purl.obolibrary.org/obo/UPHENO_0081455
+http://purl.obolibrary.org/obo/UBERON_0003646	http://purl.obolibrary.org/obo/UPHENO_0081456
+http://purl.obolibrary.org/obo/UBERON_0004336	http://purl.obolibrary.org/obo/UPHENO_0081457
+http://purl.obolibrary.org/obo/UBERON_0001105	http://purl.obolibrary.org/obo/UPHENO_0081458
+http://purl.obolibrary.org/obo/UBERON_0004337	http://purl.obolibrary.org/obo/UPHENO_0081459
+http://purl.obolibrary.org/obo/UBERON_0004334	http://purl.obolibrary.org/obo/UPHENO_0081460
+http://purl.obolibrary.org/obo/UBERON_0002397	http://purl.obolibrary.org/obo/UPHENO_0081461
+http://purl.obolibrary.org/obo/UBERON_0003641	http://purl.obolibrary.org/obo/UPHENO_0081462
+http://purl.obolibrary.org/obo/UBERON_0003642	http://purl.obolibrary.org/obo/UPHENO_0081463
+http://purl.obolibrary.org/obo/UBERON_0004335	http://purl.obolibrary.org/obo/UPHENO_0081464
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diff --git a/src/curation/upheno-fillers/hp/aplasticHypoplasticAnatomicalEntity.tsv b/src/curation/upheno-fillers/hp/aplasticHypoplasticAnatomicalEntity.tsv
new file mode 100644
index 00000000..d09edc63
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/aplasticHypoplasticAnatomicalEntity.tsv
@@ -0,0 +1,146 @@
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+http://purl.obolibrary.org/obo/UBERON_0000981	http://purl.obolibrary.org/obo/UPHENO_0080172
+http://purl.obolibrary.org/obo/UBERON_0001435	http://purl.obolibrary.org/obo/UPHENO_0080173
+http://purl.obolibrary.org/obo/UBERON_0001275	http://purl.obolibrary.org/obo/UPHENO_0080174
+http://purl.obolibrary.org/obo/UBERON_0001155	http://purl.obolibrary.org/obo/UPHENO_0080175
+http://purl.obolibrary.org/obo/UBERON_0002244	http://purl.obolibrary.org/obo/UPHENO_0080176
+http://purl.obolibrary.org/obo/UBERON_0001705	http://purl.obolibrary.org/obo/UPHENO_0080177
+http://purl.obolibrary.org/obo/UBERON_0001825	http://purl.obolibrary.org/obo/UPHENO_0080178
+http://purl.obolibrary.org/obo/UBERON_0000979	http://purl.obolibrary.org/obo/UPHENO_0080179
+http://purl.obolibrary.org/obo/UBERON_0001706	http://purl.obolibrary.org/obo/UPHENO_0080180
+http://purl.obolibrary.org/obo/UBERON_0000975	http://purl.obolibrary.org/obo/UPHENO_0080181
+http://purl.obolibrary.org/obo/UBERON_0000976	http://purl.obolibrary.org/obo/UPHENO_0080182
+http://purl.obolibrary.org/obo/UBERON_0010887	http://purl.obolibrary.org/obo/UPHENO_0080183
+http://purl.obolibrary.org/obo/UBERON_0002196	http://purl.obolibrary.org/obo/UPHENO_0080184
+http://purl.obolibrary.org/obo/UBERON_0001424	http://purl.obolibrary.org/obo/UPHENO_0080185
+http://purl.obolibrary.org/obo/UBERON_0001786	http://purl.obolibrary.org/obo/UPHENO_0080186
+http://purl.obolibrary.org/obo/UBERON_0001423	http://purl.obolibrary.org/obo/UPHENO_0080187
+http://purl.obolibrary.org/obo/UBERON_0000053	http://purl.obolibrary.org/obo/UPHENO_0080188
+http://purl.obolibrary.org/obo/UBERON_0004412	http://purl.obolibrary.org/obo/UPHENO_0080189
+http://purl.obolibrary.org/obo/UBERON_0002355	http://purl.obolibrary.org/obo/UPHENO_0080190
+http://purl.obolibrary.org/obo/UBERON_0002234	http://purl.obolibrary.org/obo/UPHENO_0080191
+http://purl.obolibrary.org/obo/UBERON_0001817	http://purl.obolibrary.org/obo/UPHENO_0080192
+http://purl.obolibrary.org/obo/UBERON_0002228	http://purl.obolibrary.org/obo/UPHENO_0080193
+http://purl.obolibrary.org/obo/UBERON_0000965	http://purl.obolibrary.org/obo/UPHENO_0080194
+http://purl.obolibrary.org/obo/UBERON_0000966	http://purl.obolibrary.org/obo/UPHENO_0080195
+http://purl.obolibrary.org/obo/UBERON_0001130	http://purl.obolibrary.org/obo/UPHENO_0080196
+http://purl.obolibrary.org/obo/UBERON_0001377	http://purl.obolibrary.org/obo/UPHENO_0080197
+http://purl.obolibrary.org/obo/UBERON_0002106	http://purl.obolibrary.org/obo/UPHENO_0080198
+http://purl.obolibrary.org/obo/UBERON_0001255	http://purl.obolibrary.org/obo/UPHENO_0080199
+http://purl.obolibrary.org/obo/UBERON_0001893	http://purl.obolibrary.org/obo/UPHENO_0080200
+http://purl.obolibrary.org/obo/UBERON_0001769	http://purl.obolibrary.org/obo/UPHENO_0080201
+http://purl.obolibrary.org/obo/UBERON_0001768	http://purl.obolibrary.org/obo/UPHENO_0080202
+http://purl.obolibrary.org/obo/UBERON_0000310	http://purl.obolibrary.org/obo/UPHENO_0080203
+http://purl.obolibrary.org/obo/UBERON_0002336	http://purl.obolibrary.org/obo/UPHENO_0080204
+http://purl.obolibrary.org/obo/UBERON_0002298	http://purl.obolibrary.org/obo/UPHENO_0080205
+http://purl.obolibrary.org/obo/UBERON_0001760	http://purl.obolibrary.org/obo/UPHENO_0080206
+http://purl.obolibrary.org/obo/UBERON_0001756	http://purl.obolibrary.org/obo/UPHENO_0080207
+http://purl.obolibrary.org/obo/UBERON_0000941	http://purl.obolibrary.org/obo/UPHENO_0080208
+http://purl.obolibrary.org/obo/UBERON_0010230	http://purl.obolibrary.org/obo/UPHENO_0080209
diff --git a/src/curation/upheno-fillers/hp/atreticAnatomicalEntity.tsv b/src/curation/upheno-fillers/hp/atreticAnatomicalEntity.tsv
new file mode 100644
index 00000000..e8aed051
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/atreticAnatomicalEntity.tsv
@@ -0,0 +1,32 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0000160	http://purl.obolibrary.org/obo/UPHENO_0063629
+http://purl.obolibrary.org/obo/UBERON_0001173	http://purl.obolibrary.org/obo/UPHENO_0063630
+http://purl.obolibrary.org/obo/UBERON_0002185	http://purl.obolibrary.org/obo/UPHENO_0063631
+http://purl.obolibrary.org/obo/UBERON_0001052	http://purl.obolibrary.org/obo/UPHENO_0063632
+http://purl.obolibrary.org/obo/UBERON_0001334	http://purl.obolibrary.org/obo/UPHENO_0080060
+http://purl.obolibrary.org/obo/UBERON_0001850	http://purl.obolibrary.org/obo/UPHENO_0063634
+http://purl.obolibrary.org/obo/UBERON_0001333	http://purl.obolibrary.org/obo/UPHENO_0080061
+http://purl.obolibrary.org/obo/UBERON_0001352	http://purl.obolibrary.org/obo/UPHENO_0063616
+http://purl.obolibrary.org/obo/UBERON_0002146	http://purl.obolibrary.org/obo/UPHENO_0063591
+http://purl.obolibrary.org/obo/UBERON_0001155	http://purl.obolibrary.org/obo/UPHENO_0063617
+http://purl.obolibrary.org/obo/UBERON_0003704	http://purl.obolibrary.org/obo/UPHENO_0063637
+http://purl.obolibrary.org/obo/UBERON_0000996	http://purl.obolibrary.org/obo/UPHENO_0063593
+http://purl.obolibrary.org/obo/UBERON_0005409	http://purl.obolibrary.org/obo/UPHENO_0063639
+http://purl.obolibrary.org/obo/UBERON_0003703	http://purl.obolibrary.org/obo/UPHENO_0063640
+http://purl.obolibrary.org/obo/UBERON_0010284	http://purl.obolibrary.org/obo/UPHENO_0063641
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0063565
+http://purl.obolibrary.org/obo/UBERON_0002393	http://purl.obolibrary.org/obo/UPHENO_0063620
+http://purl.obolibrary.org/obo/UBERON_0004110	http://purl.obolibrary.org/obo/UPHENO_0063643
+http://purl.obolibrary.org/obo/UBERON_0004771	http://purl.obolibrary.org/obo/UPHENO_0063621
+http://purl.obolibrary.org/obo/UBERON_0002137	http://purl.obolibrary.org/obo/UPHENO_0063597
+http://purl.obolibrary.org/obo/UBERON_0002115	http://purl.obolibrary.org/obo/UPHENO_0063567
+http://purl.obolibrary.org/obo/UBERON_0000057	http://purl.obolibrary.org/obo/UPHENO_0063568
+http://purl.obolibrary.org/obo/UBERON_0001245	http://purl.obolibrary.org/obo/UPHENO_0063599
+http://purl.obolibrary.org/obo/UBERON_0002114	http://purl.obolibrary.org/obo/UPHENO_0063569
+http://purl.obolibrary.org/obo/UBERON_0003126	http://purl.obolibrary.org/obo/UPHENO_0063624
+http://purl.obolibrary.org/obo/UBERON_0002116	http://purl.obolibrary.org/obo/UPHENO_0063571
+http://purl.obolibrary.org/obo/UBERON_0002012	http://purl.obolibrary.org/obo/UPHENO_0063646
+http://purl.obolibrary.org/obo/UBERON_0001043	http://purl.obolibrary.org/obo/UPHENO_0063603
+http://purl.obolibrary.org/obo/UBERON_0001166	http://purl.obolibrary.org/obo/UPHENO_0063647
+http://purl.obolibrary.org/obo/UBERON_0000056	http://purl.obolibrary.org/obo/UPHENO_0063627
+http://purl.obolibrary.org/obo/UBERON_0001737	http://purl.obolibrary.org/obo/UPHENO_0063628
diff --git a/src/curation/upheno-fillers/hp/atrophiedAnatomicalEntity.tsv b/src/curation/upheno-fillers/hp/atrophiedAnatomicalEntity.tsv
new file mode 100644
index 00000000..7eafbd32
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/atrophiedAnatomicalEntity.tsv
@@ -0,0 +1,47 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0004482	http://purl.obolibrary.org/obo/UPHENO_0014120
+http://purl.obolibrary.org/obo/CL_0000100	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0004480	http://purl.obolibrary.org/obo/UPHENO_0014121
+http://purl.obolibrary.org/obo/UBERON_0004481	http://purl.obolibrary.org/obo/UPHENO_0014122
+http://purl.obolibrary.org/obo/UBERON_0001873	http://purl.obolibrary.org/obo/UPHENO_0014064
+http://purl.obolibrary.org/obo/UBERON_0001378	http://purl.obolibrary.org/obo/UPHENO_0014125
+http://purl.obolibrary.org/obo/UBERON_0001213	http://purl.obolibrary.org/obo/UPHENO_0013958
+http://purl.obolibrary.org/obo/UBERON_0001597	http://purl.obolibrary.org/obo/UPHENO_0014065
+http://purl.obolibrary.org/obo/UBERON_0009132	http://purl.obolibrary.org/obo/UPHENO_0014128
+http://purl.obolibrary.org/obo/UBERON_0001377	http://purl.obolibrary.org/obo/UPHENO_0014129
+http://purl.obolibrary.org/obo/UBERON_0003951	http://purl.obolibrary.org/obo/UPHENO_0014130
+http://purl.obolibrary.org/obo/UBERON_0003897	http://purl.obolibrary.org/obo/UPHENO_0014066
+http://purl.obolibrary.org/obo/UBERON_0004103	http://purl.obolibrary.org/obo/UPHENO_0013922
+http://purl.obolibrary.org/obo/UBERON_0001495	http://purl.obolibrary.org/obo/UPHENO_0014132
+http://purl.obolibrary.org/obo/UBERON_0001231	http://purl.obolibrary.org/obo/UPHENO_0013924
+http://purl.obolibrary.org/obo/UBERON_0004720	http://purl.obolibrary.org/obo/UPHENO_0014081
+http://purl.obolibrary.org/obo/UBERON_0004489	http://purl.obolibrary.org/obo/UPHENO_0014133
+http://purl.obolibrary.org/obo/UBERON_0001893	http://purl.obolibrary.org/obo/UPHENO_0014134
+http://purl.obolibrary.org/obo/UBERON_0002421	http://purl.obolibrary.org/obo/UPHENO_0014082
+http://purl.obolibrary.org/obo/UBERON_0001497	http://purl.obolibrary.org/obo/UPHENO_0014135
+http://purl.obolibrary.org/obo/UBERON_0000956	http://purl.obolibrary.org/obo/UPHENO_0014137
+http://purl.obolibrary.org/obo/UBERON_0001502	http://purl.obolibrary.org/obo/UPHENO_0014069
+http://purl.obolibrary.org/obo/UBERON_0001769	http://purl.obolibrary.org/obo/UPHENO_0014052
+http://purl.obolibrary.org/obo/UBERON_0001604	http://purl.obolibrary.org/obo/UPHENO_0014084
+http://purl.obolibrary.org/obo/UBERON_0000955	http://purl.obolibrary.org/obo/UPHENO_0014053
+http://purl.obolibrary.org/obo/UBERON_0007709	http://purl.obolibrary.org/obo/UPHENO_0014087
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0013936
+http://purl.obolibrary.org/obo/UBERON_0004471	http://purl.obolibrary.org/obo/UPHENO_0014140
+http://purl.obolibrary.org/obo/UBERON_0002097	http://purl.obolibrary.org/obo/UPHENO_0014089
+http://purl.obolibrary.org/obo/UBERON_0002037	http://purl.obolibrary.org/obo/UPHENO_0013942
+http://purl.obolibrary.org/obo/UBERON_0008230	http://purl.obolibrary.org/obo/UPHENO_0078056
+http://purl.obolibrary.org/obo/UBERON_0002336	http://purl.obolibrary.org/obo/UPHENO_0014141
+http://purl.obolibrary.org/obo/UBERON_0001225	http://purl.obolibrary.org/obo/UPHENO_0013944
+http://purl.obolibrary.org/obo/UBERON_0002132	http://purl.obolibrary.org/obo/UPHENO_0014093
+http://purl.obolibrary.org/obo/UBERON_0002113	http://purl.obolibrary.org/obo/UPHENO_0014019
+http://purl.obolibrary.org/obo/UBERON_0006533	http://purl.obolibrary.org/obo/UPHENO_0014144
+http://purl.obolibrary.org/obo/UBERON_0000473	http://purl.obolibrary.org/obo/UPHENO_0013986
+http://purl.obolibrary.org/obo/UBERON_0004476	http://purl.obolibrary.org/obo/UPHENO_0014145
+http://purl.obolibrary.org/obo/UBERON_0018254	http://purl.obolibrary.org/obo/UPHENO_0014111
+http://purl.obolibrary.org/obo/UBERON_0002707	http://purl.obolibrary.org/obo/UPHENO_0014071
+http://purl.obolibrary.org/obo/UBERON_0002988	http://purl.obolibrary.org/obo/UPHENO_0014112
+http://purl.obolibrary.org/obo/UBERON_0000941	http://purl.obolibrary.org/obo/UPHENO_0014062
+http://purl.obolibrary.org/obo/UBERON_0000007	http://purl.obolibrary.org/obo/UPHENO_0014072
+http://purl.obolibrary.org/obo/UBERON_0002129	http://purl.obolibrary.org/obo/UPHENO_0014097
+http://purl.obolibrary.org/obo/UBERON_0001898	http://purl.obolibrary.org/obo/UPHENO_0014114
+http://purl.obolibrary.org/obo/UBERON_0014376	http://purl.obolibrary.org/obo/UPHENO_0014077
diff --git a/src/curation/upheno-fillers/hp/bifurcatedAnatomicalEntity.tsv b/src/curation/upheno-fillers/hp/bifurcatedAnatomicalEntity.tsv
new file mode 100644
index 00000000..f5e7c23f
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/bifurcatedAnatomicalEntity.tsv
@@ -0,0 +1,3 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0055805
+http://purl.obolibrary.org/obo/UBERON_0000975	http://purl.obolibrary.org/obo/UPHENO_0055800
diff --git a/src/curation/upheno-fillers/hp/brokenAnatomicalEntity.tsv b/src/curation/upheno-fillers/hp/brokenAnatomicalEntity.tsv
new file mode 100644
index 00000000..c4f9fcc8
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/brokenAnatomicalEntity.tsv
@@ -0,0 +1,7 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0081401
+http://purl.obolibrary.org/obo/UBERON_0004395	http://purl.obolibrary.org/obo/UPHENO_0081408
+http://purl.obolibrary.org/obo/UBERON_0000976	http://purl.obolibrary.org/obo/UPHENO_0081409
+http://purl.obolibrary.org/obo/UBERON_0004390	http://purl.obolibrary.org/obo/UPHENO_0081410
+http://purl.obolibrary.org/obo/UBERON_0004391	http://purl.obolibrary.org/obo/UPHENO_0081411
+http://purl.obolibrary.org/obo/UBERON_0004387	http://purl.obolibrary.org/obo/UPHENO_0081412
diff --git a/src/curation/upheno-fillers/hp/calcifiedAnatomicalEntity.tsv b/src/curation/upheno-fillers/hp/calcifiedAnatomicalEntity.tsv
new file mode 100644
index 00000000..05fcb68b
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/calcifiedAnatomicalEntity.tsv
@@ -0,0 +1,63 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0005396	http://purl.obolibrary.org/obo/UPHENO_0067828
+http://purl.obolibrary.org/obo/UBERON_0008987	http://purl.obolibrary.org/obo/UPHENO_0076956
+http://purl.obolibrary.org/obo/UBERON_0001070	http://purl.obolibrary.org/obo/UPHENO_0067829
+http://purl.obolibrary.org/obo/UBERON_0002049	http://purl.obolibrary.org/obo/UPHENO_0067830
+http://purl.obolibrary.org/obo/UBERON_0001435	http://purl.obolibrary.org/obo/UPHENO_0084186
+http://purl.obolibrary.org/obo/UBERON_0001633	http://purl.obolibrary.org/obo/UPHENO_0067833
+http://purl.obolibrary.org/obo/UBERON_0001754	http://purl.obolibrary.org/obo/UPHENO_0084187
+http://purl.obolibrary.org/obo/UBERON_0001875	http://purl.obolibrary.org/obo/UPHENO_0067834
+http://purl.obolibrary.org/obo/UBERON_0002369	http://purl.obolibrary.org/obo/UPHENO_0067887
+http://purl.obolibrary.org/obo/UBERON_0005995	http://purl.obolibrary.org/obo/UPHENO_0084188
+http://purl.obolibrary.org/obo/UBERON_0007610	http://purl.obolibrary.org/obo/UPHENO_0084189
+http://purl.obolibrary.org/obo/UBERON_0001627	http://purl.obolibrary.org/obo/UPHENO_0084190
+http://purl.obolibrary.org/obo/UBERON_0001828	http://purl.obolibrary.org/obo/UPHENO_0084191
+http://purl.obolibrary.org/obo/UBERON_0001905	http://purl.obolibrary.org/obo/UPHENO_0067839
+http://purl.obolibrary.org/obo/UBERON_0001508	http://purl.obolibrary.org/obo/UPHENO_0067763
+http://purl.obolibrary.org/obo/UBERON_0001987	http://purl.obolibrary.org/obo/UPHENO_0067841
+http://purl.obolibrary.org/obo/UBERON_0001867	http://purl.obolibrary.org/obo/UPHENO_0067842
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0067765
+http://purl.obolibrary.org/obo/UBERON_0004572	http://purl.obolibrary.org/obo/UPHENO_0084192
+http://purl.obolibrary.org/obo/UBERON_0007844	http://purl.obolibrary.org/obo/UPHENO_0067766
+http://purl.obolibrary.org/obo/UBERON_0002236	http://purl.obolibrary.org/obo/UPHENO_0067894
+http://purl.obolibrary.org/obo/UBERON_0002037	http://purl.obolibrary.org/obo/UPHENO_0067845
+http://purl.obolibrary.org/obo/UBERON_0011818	http://purl.obolibrary.org/obo/UPHENO_0067846
+http://purl.obolibrary.org/obo/UBERON_0003126	http://purl.obolibrary.org/obo/UPHENO_0067847
+http://purl.obolibrary.org/obo/UBERON_0004535	http://purl.obolibrary.org/obo/UPHENO_0084193
+http://purl.obolibrary.org/obo/UBERON_0001621	http://purl.obolibrary.org/obo/UPHENO_0067848
+http://purl.obolibrary.org/obo/UBERON_0001066	http://purl.obolibrary.org/obo/UPHENO_0067775
+http://purl.obolibrary.org/obo/UBERON_0001264	http://purl.obolibrary.org/obo/UPHENO_0067776
+http://purl.obolibrary.org/obo/UBERON_0001737	http://purl.obolibrary.org/obo/UPHENO_0067850
+http://purl.obolibrary.org/obo/UBERON_0004408	http://purl.obolibrary.org/obo/UPHENO_0067901
+http://purl.obolibrary.org/obo/UBERON_0002107	http://purl.obolibrary.org/obo/UPHENO_0067902
+http://purl.obolibrary.org/obo/UBERON_0002349	http://purl.obolibrary.org/obo/UPHENO_0082496
+http://purl.obolibrary.org/obo/UBERON_0000007	http://purl.obolibrary.org/obo/UPHENO_0067852
+http://purl.obolibrary.org/obo/UBERON_0001535	http://purl.obolibrary.org/obo/UPHENO_0067903
+http://purl.obolibrary.org/obo/UBERON_0000966	http://purl.obolibrary.org/obo/UPHENO_0067783
+http://purl.obolibrary.org/obo/UBERON_0011742	http://purl.obolibrary.org/obo/UPHENO_0084194
+http://purl.obolibrary.org/obo/UBERON_0002060	http://purl.obolibrary.org/obo/UPHENO_0084195
+http://purl.obolibrary.org/obo/UBERON_0007151	http://purl.obolibrary.org/obo/UPHENO_0084196
+http://purl.obolibrary.org/obo/UBERON_0001015	http://purl.obolibrary.org/obo/UPHENO_0067913
+http://purl.obolibrary.org/obo/UBERON_0001532	http://purl.obolibrary.org/obo/UPHENO_0067914
+http://purl.obolibrary.org/obo/UBERON_0004449	http://purl.obolibrary.org/obo/UPHENO_0067859
+http://purl.obolibrary.org/obo/UBERON_0007239	http://purl.obolibrary.org/obo/UPHENO_0084197
+http://purl.obolibrary.org/obo/UBERON_0001893	http://purl.obolibrary.org/obo/UPHENO_0067915
+http://purl.obolibrary.org/obo/UBERON_0002420	http://purl.obolibrary.org/obo/UPHENO_0067863
+http://purl.obolibrary.org/obo/UBERON_0005609	http://purl.obolibrary.org/obo/UPHENO_0084198
+http://purl.obolibrary.org/obo/UBERON_0001447	http://purl.obolibrary.org/obo/UPHENO_0067866
+http://purl.obolibrary.org/obo/UBERON_0002293	http://purl.obolibrary.org/obo/UPHENO_0084199
+http://purl.obolibrary.org/obo/UBERON_0010743	http://purl.obolibrary.org/obo/UPHENO_0067921
+http://purl.obolibrary.org/obo/UBERON_0002137	http://purl.obolibrary.org/obo/UPHENO_0067809
+http://purl.obolibrary.org/obo/UBERON_0003701	http://purl.obolibrary.org/obo/UPHENO_0067811
+http://purl.obolibrary.org/obo/UBERON_0001886	http://purl.obolibrary.org/obo/UPHENO_0067923
+http://purl.obolibrary.org/obo/UBERON_0002132	http://purl.obolibrary.org/obo/UPHENO_0067875
+http://purl.obolibrary.org/obo/UBERON_0002135	http://purl.obolibrary.org/obo/UPHENO_0067818
+http://purl.obolibrary.org/obo/UBERON_0006059	http://purl.obolibrary.org/obo/UPHENO_0067877
+http://purl.obolibrary.org/obo/UBERON_0000991	http://purl.obolibrary.org/obo/UPHENO_0067879
+http://purl.obolibrary.org/obo/UBERON_0002299	http://purl.obolibrary.org/obo/UPHENO_0067819
+http://purl.obolibrary.org/obo/UBERON_0000946	http://purl.obolibrary.org/obo/UPHENO_0067821
+http://purl.obolibrary.org/obo/UBERON_0000947	http://purl.obolibrary.org/obo/UPHENO_0067822
+http://purl.obolibrary.org/obo/UBERON_0001516	http://purl.obolibrary.org/obo/UPHENO_0084200
+http://purl.obolibrary.org/obo/UBERON_0001637	http://purl.obolibrary.org/obo/UPHENO_0067824
+http://purl.obolibrary.org/obo/UBERON_0004703	http://purl.obolibrary.org/obo/UPHENO_0067882
+http://purl.obolibrary.org/obo/UBERON_0001515	http://purl.obolibrary.org/obo/UPHENO_0067825
diff --git a/src/curation/upheno-fillers/hp/cystInLocation-modified.tsv b/src/curation/upheno-fillers/hp/cystInLocation-modified.tsv
new file mode 100644
index 00000000..91afb082
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/cystInLocation-modified.tsv
@@ -0,0 +1,9 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001905	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0003704	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0000007	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002037	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0004090	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002420	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002068	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/hp/cystInLocation.tsv b/src/curation/upheno-fillers/hp/cystInLocation.tsv
new file mode 100644
index 00000000..4e7ecb44
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/cystInLocation.tsv
@@ -0,0 +1,9 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0081065
+http://purl.obolibrary.org/obo/UBERON_0001905	http://purl.obolibrary.org/obo/UPHENO_0081070
+http://purl.obolibrary.org/obo/UBERON_0003704	http://purl.obolibrary.org/obo/UPHENO_0081071
+http://purl.obolibrary.org/obo/UBERON_0000007	http://purl.obolibrary.org/obo/UPHENO_0081072
+http://purl.obolibrary.org/obo/UBERON_0002037	http://purl.obolibrary.org/obo/UPHENO_0081073
+http://purl.obolibrary.org/obo/UBERON_0004090	http://purl.obolibrary.org/obo/UPHENO_0081074
+http://purl.obolibrary.org/obo/UBERON_0002420	http://purl.obolibrary.org/obo/UPHENO_0081075
+http://purl.obolibrary.org/obo/UBERON_0002068	http://purl.obolibrary.org/obo/UPHENO_0081076
diff --git a/src/curation/upheno-fillers/hp/damagedAnatomicalEntityInLocation.tsv b/src/curation/upheno-fillers/hp/damagedAnatomicalEntityInLocation.tsv
new file mode 100644
index 00000000..3335e436
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/damagedAnatomicalEntityInLocation.tsv
@@ -0,0 +1,3 @@
+anatomical_entity	location	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0001027	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0030424	http://purl.obolibrary.org/obo/UBERON_0001027	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/hp/decreasedProportionOfCellTypeInLocation.tsv b/src/curation/upheno-fillers/hp/decreasedProportionOfCellTypeInLocation.tsv
new file mode 100644
index 00000000..699d6859
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/decreasedProportionOfCellTypeInLocation.tsv
@@ -0,0 +1,3 @@
+cell	location	defined_class
+http://purl.obolibrary.org/obo/CL_0000792	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0081386
+http://purl.obolibrary.org/obo/CL_0000000	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0081387
diff --git a/src/curation/upheno-fillers/hp/decreasedProportionOfCellTypeTowardsCellTypeInLocation.tsv b/src/curation/upheno-fillers/hp/decreasedProportionOfCellTypeTowardsCellTypeInLocation.tsv
new file mode 100644
index 00000000..419f7487
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/decreasedProportionOfCellTypeTowardsCellTypeInLocation.tsv
@@ -0,0 +1,50 @@
+cell	compared_cell	location	defined_class
+http://purl.obolibrary.org/obo/CL_0001062	http://purl.obolibrary.org/obo/CL_0000084	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0082559
+http://purl.obolibrary.org/obo/CL_0000492	http://purl.obolibrary.org/obo/CL_0000000	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0082560
+http://purl.obolibrary.org/obo/CL_0000818	http://purl.obolibrary.org/obo/CL_0000236	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0082562
+http://purl.obolibrary.org/obo/CL_0000492	http://purl.obolibrary.org/obo/CL_0000084	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0082565
+http://purl.obolibrary.org/obo/CL_0000895	http://purl.obolibrary.org/obo/CL_0000000	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0082566
+http://purl.obolibrary.org/obo/CL_0000897	http://purl.obolibrary.org/obo/CL_0000084	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0082567
+http://purl.obolibrary.org/obo/CL_0000000	http://purl.obolibrary.org/obo/CL_0000236	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0082568
+http://purl.obolibrary.org/obo/CL_0000895	http://purl.obolibrary.org/obo/CL_0000084	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0082569
+http://purl.obolibrary.org/obo/CL_0001062	http://purl.obolibrary.org/obo/CL_0000000	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0082570
+http://purl.obolibrary.org/obo/CL_0000788	http://purl.obolibrary.org/obo/CL_0000000	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0082572
+http://purl.obolibrary.org/obo/CL_0000787	http://purl.obolibrary.org/obo/CL_0000000	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0082574
+http://purl.obolibrary.org/obo/CL_0000816	http://purl.obolibrary.org/obo/CL_0000236	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0082576
+http://purl.obolibrary.org/obo/CL_0000799	http://purl.obolibrary.org/obo/CL_0000000	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0082577
+http://purl.obolibrary.org/obo/CL_0000799	http://purl.obolibrary.org/obo/CL_0000084	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0082579
+http://purl.obolibrary.org/obo/CL_0000798	http://purl.obolibrary.org/obo/CL_0000000	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0082580
+http://purl.obolibrary.org/obo/CL_0000788	http://purl.obolibrary.org/obo/CL_0000236	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0082582
+http://purl.obolibrary.org/obo/CL_0000787	http://purl.obolibrary.org/obo/CL_0000236	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0082583
+http://purl.obolibrary.org/obo/CL_0000980	http://purl.obolibrary.org/obo/CL_0000236	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0082589
+http://purl.obolibrary.org/obo/CL_0001044	http://purl.obolibrary.org/obo/CL_0000000	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0082590
+http://purl.obolibrary.org/obo/CL_0001044	http://purl.obolibrary.org/obo/CL_0000084	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0082591
+http://purl.obolibrary.org/obo/CL_0000000	http://purl.obolibrary.org/obo/CL_0000084	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0082598
+http://purl.obolibrary.org/obo/CL_0000000	http://purl.obolibrary.org/obo/CL_0000000	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0082603
+http://purl.obolibrary.org/obo/CL_0000898	http://purl.obolibrary.org/obo/CL_0000000	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0082605
+http://purl.obolibrary.org/obo/CL_0000813	http://purl.obolibrary.org/obo/CL_0000000	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0082606
+http://purl.obolibrary.org/obo/CL_0000816	http://purl.obolibrary.org/obo/CL_0000000	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0082607
+http://purl.obolibrary.org/obo/CL_0000898	http://purl.obolibrary.org/obo/CL_0000084	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0082608
+http://purl.obolibrary.org/obo/CL_0000897	http://purl.obolibrary.org/obo/CL_0000000	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0082609
+http://purl.obolibrary.org/obo/CL_0000813	http://purl.obolibrary.org/obo/CL_0000084	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0082610
+http://purl.obolibrary.org/obo/CL_0000818	http://purl.obolibrary.org/obo/CL_0000000	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0082611
+http://purl.obolibrary.org/obo/CL_0000972	http://purl.obolibrary.org/obo/CL_0000000	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0082615
+http://purl.obolibrary.org/obo/CL_0000970	http://purl.obolibrary.org/obo/CL_0000000	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0082616
+http://purl.obolibrary.org/obo/CL_0000907	http://purl.obolibrary.org/obo/CL_0000084	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0082617
+http://purl.obolibrary.org/obo/CL_0000970	http://purl.obolibrary.org/obo/CL_0000236	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0082618
+http://purl.obolibrary.org/obo/CL_0000624	http://purl.obolibrary.org/obo/CL_0000000	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0082619
+http://purl.obolibrary.org/obo/CL_0000625	http://purl.obolibrary.org/obo/CL_0000000	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0082620
+http://purl.obolibrary.org/obo/CL_0000972	http://purl.obolibrary.org/obo/CL_0000236	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0082621
+http://purl.obolibrary.org/obo/CL_0000909	http://purl.obolibrary.org/obo/CL_0000000	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0082623
+http://purl.obolibrary.org/obo/CL_0000907	http://purl.obolibrary.org/obo/CL_0000000	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0082624
+http://purl.obolibrary.org/obo/CL_0000909	http://purl.obolibrary.org/obo/CL_0000084	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0082625
+http://purl.obolibrary.org/obo/CL_0000624	http://purl.obolibrary.org/obo/CL_0000084	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0082626
+http://purl.obolibrary.org/obo/CL_0000625	http://purl.obolibrary.org/obo/CL_0000084	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0082627
+http://purl.obolibrary.org/obo/CL_0000980	http://purl.obolibrary.org/obo/CL_0000000	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0082628
+http://purl.obolibrary.org/obo/CL_0000913	http://purl.obolibrary.org/obo/CL_0000084	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0082629
+http://purl.obolibrary.org/obo/CL_0000912	http://purl.obolibrary.org/obo/CL_0000000	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0082630
+http://purl.obolibrary.org/obo/CL_0000912	http://purl.obolibrary.org/obo/CL_0000084	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0082631
+http://purl.obolibrary.org/obo/CL_0000913	http://purl.obolibrary.org/obo/CL_0000000	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0082634
+http://purl.obolibrary.org/obo/CL_0000798	http://purl.obolibrary.org/obo/CL_0000084	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0082639
+http://purl.obolibrary.org/obo/CL_0000845	http://purl.obolibrary.org/obo/CL_0000000	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0082640
+http://purl.obolibrary.org/obo/CL_0000845	http://purl.obolibrary.org/obo/CL_0000236	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0082646
diff --git a/src/curation/upheno-fillers/hp/deviationTowardsLateralSideOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/hp/deviationTowardsLateralSideOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..8c5f5605
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/deviationTowardsLateralSideOfAnatomicalEntity.tsv
@@ -0,0 +1,16 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0004452	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0003634	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001466	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0003623	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0003635	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002389	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0003624	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0003632	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0003633	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0003622	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0003631	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002398	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001463	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0003625	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/hp/deviationTowardsTheMedialSideOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/hp/deviationTowardsTheMedialSideOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..bcc298ec
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/deviationTowardsTheMedialSideOfAnatomicalEntity.tsv
@@ -0,0 +1,18 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002544	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0003623	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0003634	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001466	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0003624	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0003635	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002389	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0003632	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0004314	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0003622	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0003633	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0004337	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0003631	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001463	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002398	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0003625	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/hp/dislocatedAnatomicalEntity.tsv b/src/curation/upheno-fillers/hp/dislocatedAnatomicalEntity.tsv
new file mode 100644
index 00000000..5fde8c9c
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/dislocatedAnatomicalEntity.tsv
@@ -0,0 +1,11 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0004452	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001466	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0000982	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0006767	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002446	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001467	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001464	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001012	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001485	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/hp/dysplasticAnatomicalEntity.tsv b/src/curation/upheno-fillers/hp/dysplasticAnatomicalEntity.tsv
new file mode 100644
index 00000000..56e7a7e3
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/dysplasticAnatomicalEntity.tsv
@@ -0,0 +1,41 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0003690	http://purl.obolibrary.org/obo/UPHENO_0047401
+http://purl.obolibrary.org/obo/UBERON_0001130	http://purl.obolibrary.org/obo/UPHENO_0047437
+http://purl.obolibrary.org/obo/UBERON_0001752	http://purl.obolibrary.org/obo/UPHENO_0047334
+http://purl.obolibrary.org/obo/UBERON_0001037	http://purl.obolibrary.org/obo/UPHENO_0047404
+http://purl.obolibrary.org/obo/UBERON_0001751	http://purl.obolibrary.org/obo/UPHENO_0047335
+http://purl.obolibrary.org/obo/UBERON_0002369	http://purl.obolibrary.org/obo/UPHENO_0047405
+http://purl.obolibrary.org/obo/UBERON_0006767	http://purl.obolibrary.org/obo/UPHENO_0047337
+http://purl.obolibrary.org/obo/UBERON_0002446	http://purl.obolibrary.org/obo/UPHENO_0047338
+http://purl.obolibrary.org/obo/UBERON_0004720	http://purl.obolibrary.org/obo/UPHENO_0047365
+http://purl.obolibrary.org/obo/UBERON_0002421	http://purl.obolibrary.org/obo/UPHENO_0047366
+http://purl.obolibrary.org/obo/UBERON_0002146	http://purl.obolibrary.org/obo/UPHENO_0047367
+http://purl.obolibrary.org/obo/UBERON_0004288	http://purl.obolibrary.org/obo/UPHENO_0047368
+http://purl.obolibrary.org/obo/UBERON_0002420	http://purl.obolibrary.org/obo/UPHENO_0047369
+http://purl.obolibrary.org/obo/UBERON_0002046	http://purl.obolibrary.org/obo/UPHENO_0047341
+http://purl.obolibrary.org/obo/UBERON_0000956	http://purl.obolibrary.org/obo/UPHENO_0047446
+http://purl.obolibrary.org/obo/UBERON_0001705	http://purl.obolibrary.org/obo/UPHENO_0047407
+http://purl.obolibrary.org/obo/UBERON_0004618	http://purl.obolibrary.org/obo/UPHENO_0047343
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0047299
+http://purl.obolibrary.org/obo/UBERON_0010746	http://purl.obolibrary.org/obo/UPHENO_0047456
+http://purl.obolibrary.org/obo/UBERON_0002137	http://purl.obolibrary.org/obo/UPHENO_0047380
+http://purl.obolibrary.org/obo/UBERON_0002037	http://purl.obolibrary.org/obo/UPHENO_0047350
+http://purl.obolibrary.org/obo/UBERON_0001443	http://purl.obolibrary.org/obo/UPHENO_0047382
+http://purl.obolibrary.org/obo/UBERON_0001269	http://purl.obolibrary.org/obo/UPHENO_0047417
+http://purl.obolibrary.org/obo/UBERON_0002413	http://purl.obolibrary.org/obo/UPHENO_0047384
+http://purl.obolibrary.org/obo/UBERON_0002336	http://purl.obolibrary.org/obo/UPHENO_0047459
+http://purl.obolibrary.org/obo/UBERON_0001423	http://purl.obolibrary.org/obo/UPHENO_0047419
+http://purl.obolibrary.org/obo/UBERON_0001264	http://purl.obolibrary.org/obo/UPHENO_0047420
+http://purl.obolibrary.org/obo/UBERON_0002198	http://purl.obolibrary.org/obo/UPHENO_0047423
+http://purl.obolibrary.org/obo/UBERON_0001464	http://purl.obolibrary.org/obo/UPHENO_0047352
+http://purl.obolibrary.org/obo/UBERON_0002113	http://purl.obolibrary.org/obo/UPHENO_0047424
+http://purl.obolibrary.org/obo/UBERON_0000473	http://purl.obolibrary.org/obo/UPHENO_0077195
+http://purl.obolibrary.org/obo/UBERON_0000991	http://purl.obolibrary.org/obo/UPHENO_0047393
+http://purl.obolibrary.org/obo/UBERON_0009567	http://purl.obolibrary.org/obo/UPHENO_0047394
+http://purl.obolibrary.org/obo/UBERON_0000924	http://purl.obolibrary.org/obo/UPHENO_0047354
+http://purl.obolibrary.org/obo/UBERON_0001437	http://purl.obolibrary.org/obo/UPHENO_0047395
+http://purl.obolibrary.org/obo/UBERON_0000941	http://purl.obolibrary.org/obo/UPHENO_0047462
+http://purl.obolibrary.org/obo/UBERON_0001898	http://purl.obolibrary.org/obo/UPHENO_0047429
+http://purl.obolibrary.org/obo/UBERON_0004703	http://purl.obolibrary.org/obo/UPHENO_0047396
+http://purl.obolibrary.org/obo/UBERON_0004407	http://purl.obolibrary.org/obo/UPHENO_0047431
+http://purl.obolibrary.org/obo/UBERON_0001438	http://purl.obolibrary.org/obo/UPHENO_0047398
diff --git a/src/curation/upheno-fillers/hp/edematousAnatomicalEntity.tsv b/src/curation/upheno-fillers/hp/edematousAnatomicalEntity.tsv
new file mode 100644
index 00000000..c7dcc649
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/edematousAnatomicalEntity.tsv
@@ -0,0 +1,24 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0082498
+http://purl.obolibrary.org/obo/UBERON_0000160	http://purl.obolibrary.org/obo/UPHENO_0082499
+http://purl.obolibrary.org/obo/UBERON_0006761	http://purl.obolibrary.org/obo/UPHENO_0082517
+http://purl.obolibrary.org/obo/UBERON_0001042	http://purl.obolibrary.org/obo/UPHENO_0082518
+http://purl.obolibrary.org/obo/UBERON_0008878	http://purl.obolibrary.org/obo/UPHENO_0082519
+http://purl.obolibrary.org/obo/UBERON_0010708	http://purl.obolibrary.org/obo/UPHENO_0082520
+http://purl.obolibrary.org/obo/UBERON_0000982	http://purl.obolibrary.org/obo/UPHENO_0082505
+http://purl.obolibrary.org/obo/UBERON_0001630	http://purl.obolibrary.org/obo/UPHENO_0082521
+http://purl.obolibrary.org/obo/UBERON_0002048	http://purl.obolibrary.org/obo/UPHENO_0082506
+http://purl.obolibrary.org/obo/UBERON_0001456	http://purl.obolibrary.org/obo/UPHENO_0082522
+http://purl.obolibrary.org/obo/UBERON_0006558	http://purl.obolibrary.org/obo/UPHENO_0082523
+http://purl.obolibrary.org/obo/UBERON_0002402	http://purl.obolibrary.org/obo/UPHENO_0082524
+http://purl.obolibrary.org/obo/UBERON_0000053	http://purl.obolibrary.org/obo/UPHENO_0082525
+http://purl.obolibrary.org/obo/UBERON_0002420	http://purl.obolibrary.org/obo/UPHENO_0082526
+http://purl.obolibrary.org/obo/UBERON_0000978	http://purl.obolibrary.org/obo/UPHENO_0082527
+http://purl.obolibrary.org/obo/UBERON_0001737	http://purl.obolibrary.org/obo/UPHENO_0082528
+http://purl.obolibrary.org/obo/UBERON_0001723	http://purl.obolibrary.org/obo/UPHENO_0082529
+http://purl.obolibrary.org/obo/UBERON_0001712	http://purl.obolibrary.org/obo/UPHENO_0082530
+http://purl.obolibrary.org/obo/UBERON_0001777	http://purl.obolibrary.org/obo/UPHENO_0082531
+http://purl.obolibrary.org/obo/UBERON_0001711	http://purl.obolibrary.org/obo/UPHENO_0082512
+http://purl.obolibrary.org/obo/UBERON_0000922	http://purl.obolibrary.org/obo/UPHENO_0082514
+http://purl.obolibrary.org/obo/UBERON_0001713	http://purl.obolibrary.org/obo/UPHENO_0082532
+http://purl.obolibrary.org/obo/UBERON_0004090	http://purl.obolibrary.org/obo/UPHENO_0082515
diff --git a/src/curation/upheno-fillers/hp/exsertedAnatomicalEntity.tsv b/src/curation/upheno-fillers/hp/exsertedAnatomicalEntity.tsv
new file mode 100644
index 00000000..6fc5bb68
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/exsertedAnatomicalEntity.tsv
@@ -0,0 +1,7 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001052	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0000995	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0000916	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002135	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002134	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/hp/fibroticAnatomicalEntity.tsv b/src/curation/upheno-fillers/hp/fibroticAnatomicalEntity.tsv
new file mode 100644
index 00000000..e8a2dbce
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/fibroticAnatomicalEntity.tsv
@@ -0,0 +1,10 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0076294
+http://purl.obolibrary.org/obo/UBERON_0016480	http://purl.obolibrary.org/obo/UPHENO_0076295
+http://purl.obolibrary.org/obo/UBERON_0001601	http://purl.obolibrary.org/obo/UPHENO_0076296
+http://purl.obolibrary.org/obo/UBERON_0002107	http://purl.obolibrary.org/obo/UPHENO_0076297
+http://purl.obolibrary.org/obo/UBERON_0002349	http://purl.obolibrary.org/obo/UPHENO_0076298
+http://purl.obolibrary.org/obo/UBERON_0002048	http://purl.obolibrary.org/obo/UPHENO_0076299
+http://purl.obolibrary.org/obo/UBERON_0002017	http://purl.obolibrary.org/obo/UPHENO_0076300
+http://purl.obolibrary.org/obo/UBERON_0002358	http://purl.obolibrary.org/obo/UPHENO_0076301
+http://purl.obolibrary.org/obo/UBERON_0002165	http://purl.obolibrary.org/obo/UPHENO_0076302
diff --git a/src/curation/upheno-fillers/hp/foldedAnatomicalEntity.tsv b/src/curation/upheno-fillers/hp/foldedAnatomicalEntity.tsv
new file mode 100644
index 00000000..03e649a7
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/foldedAnatomicalEntity.tsv
@@ -0,0 +1,3 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002488	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/hp/fracturedAnatomicalEntity.tsv b/src/curation/upheno-fillers/hp/fracturedAnatomicalEntity.tsv
new file mode 100644
index 00000000..d1cbce58
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/fracturedAnatomicalEntity.tsv
@@ -0,0 +1,106 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001350	http://purl.obolibrary.org/obo/UPHENO_0080427
+http://purl.obolibrary.org/obo/UBERON_0003654	http://purl.obolibrary.org/obo/UPHENO_0080428
+http://purl.obolibrary.org/obo/UBERON_0006767	http://purl.obolibrary.org/obo/UPHENO_0080429
+http://purl.obolibrary.org/obo/UBERON_0002446	http://purl.obolibrary.org/obo/UPHENO_0080430
+http://purl.obolibrary.org/obo/UBERON_0008784	http://purl.obolibrary.org/obo/UPHENO_0080431
+http://purl.obolibrary.org/obo/UBERON_0003653	http://purl.obolibrary.org/obo/UPHENO_0080432
+http://purl.obolibrary.org/obo/UBERON_0003650	http://purl.obolibrary.org/obo/UPHENO_0080433
+http://purl.obolibrary.org/obo/UBERON_0008785	http://purl.obolibrary.org/obo/UPHENO_0080434
+http://purl.obolibrary.org/obo/UBERON_0001474	http://purl.obolibrary.org/obo/UPHENO_0080435
+http://purl.obolibrary.org/obo/UBERON_0012360	http://purl.obolibrary.org/obo/UPHENO_0080436
+http://purl.obolibrary.org/obo/UBERON_0001469	http://purl.obolibrary.org/obo/UPHENO_0080437
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0080438
+http://purl.obolibrary.org/obo/UBERON_0002395	http://purl.obolibrary.org/obo/UPHENO_0080439
+http://purl.obolibrary.org/obo/UBERON_0010721	http://purl.obolibrary.org/obo/UPHENO_0080440
+http://purl.obolibrary.org/obo/UBERON_0003645	http://purl.obolibrary.org/obo/UPHENO_0080442
+http://purl.obolibrary.org/obo/UBERON_0004338	http://purl.obolibrary.org/obo/UPHENO_0080443
+http://purl.obolibrary.org/obo/UBERON_0001465	http://purl.obolibrary.org/obo/UPHENO_0080444
+http://purl.obolibrary.org/obo/UBERON_0003129	http://purl.obolibrary.org/obo/UPHENO_0080445
+http://purl.obolibrary.org/obo/UBERON_0001105	http://purl.obolibrary.org/obo/UPHENO_0080446
+http://purl.obolibrary.org/obo/UBERON_0002397	http://purl.obolibrary.org/obo/UPHENO_0080447
+http://purl.obolibrary.org/obo/UBERON_0008255	http://purl.obolibrary.org/obo/UPHENO_0080448
+http://purl.obolibrary.org/obo/UBERON_0001461	http://purl.obolibrary.org/obo/UPHENO_0080449
+http://purl.obolibrary.org/obo/UBERON_0008256	http://purl.obolibrary.org/obo/UPHENO_0080450
+http://purl.obolibrary.org/obo/UBERON_0004332	http://purl.obolibrary.org/obo/UPHENO_0080451
+http://purl.obolibrary.org/obo/UBERON_0001737	http://purl.obolibrary.org/obo/UPHENO_0080452
+http://purl.obolibrary.org/obo/UBERON_0004320	http://purl.obolibrary.org/obo/UPHENO_0080453
+http://purl.obolibrary.org/obo/UBERON_0001455	http://purl.obolibrary.org/obo/UPHENO_0080454
+http://purl.obolibrary.org/obo/UBERON_0001697	http://purl.obolibrary.org/obo/UPHENO_0080455
+http://purl.obolibrary.org/obo/UBERON_0001454	http://purl.obolibrary.org/obo/UPHENO_0080456
+http://purl.obolibrary.org/obo/UBERON_0002389	http://purl.obolibrary.org/obo/UPHENO_0080457
+http://purl.obolibrary.org/obo/UBERON_0004325	http://purl.obolibrary.org/obo/UPHENO_0080458
+http://purl.obolibrary.org/obo/UBERON_0000004	http://purl.obolibrary.org/obo/UPHENO_0080459
+http://purl.obolibrary.org/obo/UBERON_0006865	http://purl.obolibrary.org/obo/UPHENO_0080460
+http://purl.obolibrary.org/obo/UBERON_0004323	http://purl.obolibrary.org/obo/UPHENO_0080461
+http://purl.obolibrary.org/obo/UBERON_0001451	http://purl.obolibrary.org/obo/UPHENO_0080462
+http://purl.obolibrary.org/obo/UBERON_0001450	http://purl.obolibrary.org/obo/UPHENO_0080463
+http://purl.obolibrary.org/obo/UBERON_0001453	http://purl.obolibrary.org/obo/UPHENO_0080464
+http://purl.obolibrary.org/obo/UBERON_0004321	http://purl.obolibrary.org/obo/UPHENO_0080465
+http://purl.obolibrary.org/obo/UBERON_0004322	http://purl.obolibrary.org/obo/UPHENO_0080466
+http://purl.obolibrary.org/obo/UBERON_0001447	http://purl.obolibrary.org/obo/UPHENO_0080467
+http://purl.obolibrary.org/obo/UBERON_0001449	http://purl.obolibrary.org/obo/UPHENO_0080468
+http://purl.obolibrary.org/obo/UBERON_0014881	http://purl.obolibrary.org/obo/UPHENO_0080469
+http://purl.obolibrary.org/obo/UBERON_0014763	http://purl.obolibrary.org/obo/UPHENO_0080470
+http://purl.obolibrary.org/obo/UBERON_0004396	http://purl.obolibrary.org/obo/UPHENO_0080471
+http://purl.obolibrary.org/obo/UBERON_0003461	http://purl.obolibrary.org/obo/UPHENO_0080472
+http://purl.obolibrary.org/obo/UBERON_0004397	http://purl.obolibrary.org/obo/UPHENO_0080473
+http://purl.obolibrary.org/obo/UBERON_0003462	http://purl.obolibrary.org/obo/UPHENO_0080474
+http://purl.obolibrary.org/obo/UBERON_0004394	http://purl.obolibrary.org/obo/UPHENO_0080475
+http://purl.obolibrary.org/obo/UBERON_0010544	http://purl.obolibrary.org/obo/UPHENO_0080476
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+http://purl.obolibrary.org/obo/UBERON_0003866	http://purl.obolibrary.org/obo/UPHENO_0080486
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+http://purl.obolibrary.org/obo/UBERON_0001446	http://purl.obolibrary.org/obo/UPHENO_0080488
+http://purl.obolibrary.org/obo/UBERON_0002414	http://purl.obolibrary.org/obo/UPHENO_0080489
+http://purl.obolibrary.org/obo/UBERON_0002413	http://purl.obolibrary.org/obo/UPHENO_0080490
+http://purl.obolibrary.org/obo/UBERON_0004315	http://purl.obolibrary.org/obo/UPHENO_0080491
+http://purl.obolibrary.org/obo/UBERON_0003864	http://purl.obolibrary.org/obo/UPHENO_0080493
+http://purl.obolibrary.org/obo/UBERON_0001445	http://purl.obolibrary.org/obo/UPHENO_0080492
+http://purl.obolibrary.org/obo/UBERON_0004312	http://purl.obolibrary.org/obo/UPHENO_0080494
+http://purl.obolibrary.org/obo/UBERON_0004313	http://purl.obolibrary.org/obo/UPHENO_0080495
+http://purl.obolibrary.org/obo/UBERON_0003466	http://purl.obolibrary.org/obo/UPHENO_0080496
+http://purl.obolibrary.org/obo/UBERON_0003620	http://purl.obolibrary.org/obo/UPHENO_0080497
+http://purl.obolibrary.org/obo/UBERON_0001684	http://purl.obolibrary.org/obo/UPHENO_0080498
+http://purl.obolibrary.org/obo/UBERON_0003221	http://purl.obolibrary.org/obo/UPHENO_0080499
+http://purl.obolibrary.org/obo/UBERON_0004311	http://purl.obolibrary.org/obo/UPHENO_0080500
+http://purl.obolibrary.org/obo/UBERON_0003464	http://purl.obolibrary.org/obo/UPHENO_0080501
+http://purl.obolibrary.org/obo/UBERON_0012291	http://purl.obolibrary.org/obo/UPHENO_0080502
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+http://purl.obolibrary.org/obo/UBERON_0001436	http://purl.obolibrary.org/obo/UPHENO_0080504
+http://purl.obolibrary.org/obo/UBERON_0006849	http://purl.obolibrary.org/obo/UPHENO_0080505
+http://purl.obolibrary.org/obo/UBERON_0003690	http://purl.obolibrary.org/obo/UPHENO_0080506
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+http://purl.obolibrary.org/obo/UBERON_0004384	http://purl.obolibrary.org/obo/UPHENO_0080508
+http://purl.obolibrary.org/obo/UBERON_0001435	http://purl.obolibrary.org/obo/UPHENO_0080509
+http://purl.obolibrary.org/obo/UBERON_0004422	http://purl.obolibrary.org/obo/UPHENO_0080510
+http://purl.obolibrary.org/obo/UBERON_0004300	http://purl.obolibrary.org/obo/UPHENO_0080511
+http://purl.obolibrary.org/obo/UBERON_0003695	http://purl.obolibrary.org/obo/UPHENO_0080512
+http://purl.obolibrary.org/obo/UBERON_0000979	http://purl.obolibrary.org/obo/UPHENO_0080513
+http://purl.obolibrary.org/obo/UBERON_0000975	http://purl.obolibrary.org/obo/UPHENO_0080514
+http://purl.obolibrary.org/obo/UBERON_0000976	http://purl.obolibrary.org/obo/UPHENO_0080515
+http://purl.obolibrary.org/obo/UBERON_0014502	http://purl.obolibrary.org/obo/UPHENO_0080516
+http://purl.obolibrary.org/obo/UBERON_0014503	http://purl.obolibrary.org/obo/UPHENO_0080517
+http://purl.obolibrary.org/obo/UBERON_0004251	http://purl.obolibrary.org/obo/UPHENO_0080518
+http://purl.obolibrary.org/obo/UBERON_0011978	http://purl.obolibrary.org/obo/UPHENO_0080519
+http://purl.obolibrary.org/obo/UBERON_0001424	http://purl.obolibrary.org/obo/UPHENO_0080520
+http://purl.obolibrary.org/obo/UBERON_0001269	http://purl.obolibrary.org/obo/UPHENO_0080521
+http://purl.obolibrary.org/obo/UBERON_0001423	http://purl.obolibrary.org/obo/UPHENO_0080522
+http://purl.obolibrary.org/obo/UBERON_0002234	http://purl.obolibrary.org/obo/UPHENO_0080523
+http://purl.obolibrary.org/obo/UBERON_0002228	http://purl.obolibrary.org/obo/UPHENO_0080524
+http://purl.obolibrary.org/obo/UBERON_0004407	http://purl.obolibrary.org/obo/UPHENO_0080525
+http://purl.obolibrary.org/obo/UBERON_0011104	http://purl.obolibrary.org/obo/UPHENO_0080526
+http://purl.obolibrary.org/obo/UBERON_0004249	http://purl.obolibrary.org/obo/UPHENO_0080528
+http://purl.obolibrary.org/obo/UBERON_0002347	http://purl.obolibrary.org/obo/UPHENO_0080529
+http://purl.obolibrary.org/obo/UBERON_0001488	http://purl.obolibrary.org/obo/UPHENO_0083030
+http://purl.obolibrary.org/obo/UBERON_0006658	http://purl.obolibrary.org/obo/UPHENO_0080530
+http://purl.obolibrary.org/obo/UBERON_0006657	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0006805	http://purl.obolibrary.org/obo/UPHENO_0080532
diff --git a/src/curation/upheno-fillers/hp/fracturedAnatomicalEntityByFractureType.tsv b/src/curation/upheno-fillers/hp/fracturedAnatomicalEntityByFractureType.tsv
new file mode 100644
index 00000000..1606b830
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/fracturedAnatomicalEntityByFractureType.tsv
@@ -0,0 +1,18 @@
+anatomical_entity	fractured	defined_class
+http://purl.obolibrary.org/obo/UBERON_0000976	http://purl.obolibrary.org/obo/PATO_0040041	http://purl.obolibrary.org/obo/UPHENO_0081611
+http://purl.obolibrary.org/obo/UBERON_0000979	http://purl.obolibrary.org/obo/PATO_0040034	http://purl.obolibrary.org/obo/UPHENO_0081612
+http://purl.obolibrary.org/obo/UBERON_0000976	http://purl.obolibrary.org/obo/PATO_0040034	http://purl.obolibrary.org/obo/UPHENO_0081613
+http://purl.obolibrary.org/obo/UBERON_0002414	http://purl.obolibrary.org/obo/PATO_0040040	http://purl.obolibrary.org/obo/UPHENO_0081614
+http://purl.obolibrary.org/obo/UBERON_0000979	http://purl.obolibrary.org/obo/PATO_0040041	http://purl.obolibrary.org/obo/UPHENO_0081615
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0040041	http://purl.obolibrary.org/obo/UPHENO_0081616
+http://purl.obolibrary.org/obo/UBERON_0004384	http://purl.obolibrary.org/obo/PATO_0040041	http://purl.obolibrary.org/obo/UPHENO_0081617
+http://purl.obolibrary.org/obo/UBERON_0002413	http://purl.obolibrary.org/obo/PATO_0040040	http://purl.obolibrary.org/obo/UPHENO_0081618
+http://purl.obolibrary.org/obo/UBERON_0002414	http://purl.obolibrary.org/obo/PATO_0040034	http://purl.obolibrary.org/obo/UPHENO_0081619
+http://purl.obolibrary.org/obo/UBERON_0002347	http://purl.obolibrary.org/obo/PATO_0040040	http://purl.obolibrary.org/obo/UPHENO_0081620
+http://purl.obolibrary.org/obo/UBERON_0002413	http://purl.obolibrary.org/obo/PATO_0040034	http://purl.obolibrary.org/obo/UPHENO_0081621
+http://purl.obolibrary.org/obo/UBERON_0002347	http://purl.obolibrary.org/obo/PATO_0040034	http://purl.obolibrary.org/obo/UPHENO_0081622
+http://purl.obolibrary.org/obo/UBERON_0002412	http://purl.obolibrary.org/obo/PATO_0040040	http://purl.obolibrary.org/obo/UPHENO_0081623
+http://purl.obolibrary.org/obo/UBERON_0002412	http://purl.obolibrary.org/obo/PATO_0040034	http://purl.obolibrary.org/obo/UPHENO_0081624
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0040034	http://purl.obolibrary.org/obo/UPHENO_0081625
+http://purl.obolibrary.org/obo/UBERON_0004384	http://purl.obolibrary.org/obo/PATO_0040034	http://purl.obolibrary.org/obo/UPHENO_0081626
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0040040	http://purl.obolibrary.org/obo/UPHENO_0081627
diff --git a/src/curation/upheno-fillers/hp/herniatedAnatomicalEntity.tsv b/src/curation/upheno-fillers/hp/herniatedAnatomicalEntity.tsv
new file mode 100644
index 00000000..5ac7f225
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/herniatedAnatomicalEntity.tsv
@@ -0,0 +1,6 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0017672	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0000996	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0003697	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002242	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/hp/hyperplasticAnatomicalEntity.tsv b/src/curation/upheno-fillers/hp/hyperplasticAnatomicalEntity.tsv
new file mode 100644
index 00000000..90210c47
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/hyperplasticAnatomicalEntity.tsv
@@ -0,0 +1,14 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0083530
+http://purl.obolibrary.org/obo/UBERON_0002370	http://purl.obolibrary.org/obo/UPHENO_0083576
+http://purl.obolibrary.org/obo/UBERON_0001295	http://purl.obolibrary.org/obo/UPHENO_0083557
+http://purl.obolibrary.org/obo/UBERON_0001173	http://purl.obolibrary.org/obo/UPHENO_0083595
+http://purl.obolibrary.org/obo/CL_0000178	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002367	http://purl.obolibrary.org/obo/UPHENO_0083512
+http://purl.obolibrary.org/obo/UBERON_0002397	http://purl.obolibrary.org/obo/UPHENO_0083596
+http://purl.obolibrary.org/obo/UBERON_0001264	http://purl.obolibrary.org/obo/UPHENO_0083541
+http://purl.obolibrary.org/obo/UBERON_0001132	http://purl.obolibrary.org/obo/UPHENO_0083566
+http://purl.obolibrary.org/obo/UBERON_0000980	http://purl.obolibrary.org/obo/UPHENO_0083597
+http://purl.obolibrary.org/obo/UBERON_0002244	http://purl.obolibrary.org/obo/UPHENO_0083598
+http://purl.obolibrary.org/obo/UBERON_0002046	http://purl.obolibrary.org/obo/UPHENO_0083525
+http://purl.obolibrary.org/obo/UBERON_0000029	http://purl.obolibrary.org/obo/UPHENO_0083593
diff --git a/src/curation/upheno-fillers/hp/hypertrophicAnatomicalEntity.tsv b/src/curation/upheno-fillers/hp/hypertrophicAnatomicalEntity.tsv
new file mode 100644
index 00000000..fd828e7e
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/hypertrophicAnatomicalEntity.tsv
@@ -0,0 +1,30 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0002084	http://purl.obolibrary.org/obo/UPHENO_0084509
+http://purl.obolibrary.org/obo/UBERON_0004084	http://purl.obolibrary.org/obo/UPHENO_0084510
+http://purl.obolibrary.org/obo/UBERON_0002080	http://purl.obolibrary.org/obo/UPHENO_0084511
+http://purl.obolibrary.org/obo/UBERON_0004481	http://purl.obolibrary.org/obo/UPHENO_0084512
+http://purl.obolibrary.org/obo/UBERON_0002389	http://purl.obolibrary.org/obo/UPHENO_0084513
+http://purl.obolibrary.org/obo/UBERON_0034908	http://purl.obolibrary.org/obo/UPHENO_0084514
+http://purl.obolibrary.org/obo/UBERON_0001577	http://purl.obolibrary.org/obo/UPHENO_0084515
+http://purl.obolibrary.org/obo/UBERON_0001255	http://purl.obolibrary.org/obo/UPHENO_0084516
+http://purl.obolibrary.org/obo/UBERON_0001848	http://purl.obolibrary.org/obo/UPHENO_0084517
+http://purl.obolibrary.org/obo/UBERON_0000978	http://purl.obolibrary.org/obo/UPHENO_0084518
+http://purl.obolibrary.org/obo/UBERON_0001828	http://purl.obolibrary.org/obo/UPHENO_0084519
+http://purl.obolibrary.org/obo/UBERON_0017692	http://purl.obolibrary.org/obo/UPHENO_0084520
+http://purl.obolibrary.org/obo/UBERON_0002217	http://purl.obolibrary.org/obo/UPHENO_0084521
+http://purl.obolibrary.org/obo/UBERON_0017690	http://purl.obolibrary.org/obo/UPHENO_0084522
+http://purl.obolibrary.org/obo/UBERON_0010000	http://purl.obolibrary.org/obo/UPHENO_0084489
+http://purl.obolibrary.org/obo/UBERON_0011156	http://purl.obolibrary.org/obo/UPHENO_0084523
+http://purl.obolibrary.org/obo/UBERON_0004176	http://purl.obolibrary.org/obo/UPHENO_0084524
+http://purl.obolibrary.org/obo/UBERON_0004252	http://purl.obolibrary.org/obo/UPHENO_0084525
+http://purl.obolibrary.org/obo/UBERON_0013778	http://purl.obolibrary.org/obo/UPHENO_0084526
+http://purl.obolibrary.org/obo/UBERON_0000310	http://purl.obolibrary.org/obo/UPHENO_0084527
+http://purl.obolibrary.org/obo/UBERON_0010708	http://purl.obolibrary.org/obo/UPHENO_0084528
+http://purl.obolibrary.org/obo/UBERON_0004339	http://purl.obolibrary.org/obo/UPHENO_0084529
+http://purl.obolibrary.org/obo/UBERON_0002411	http://purl.obolibrary.org/obo/UPHENO_0084530
+http://purl.obolibrary.org/obo/UBERON_0001446	http://purl.obolibrary.org/obo/UPHENO_0084531
+http://purl.obolibrary.org/obo/UBERON_0001567	http://purl.obolibrary.org/obo/UPHENO_0084532
+http://purl.obolibrary.org/obo/UBERON_0002377	http://purl.obolibrary.org/obo/UPHENO_0084533
+http://purl.obolibrary.org/obo/UBERON_0008775	http://purl.obolibrary.org/obo/UPHENO_0084534
+http://purl.obolibrary.org/obo/UBERON_0000945	http://purl.obolibrary.org/obo/UPHENO_0084501
+http://purl.obolibrary.org/obo/UBERON_0010890	http://purl.obolibrary.org/obo/UPHENO_0084535
diff --git a/src/curation/upheno-fillers/hp/hypoplasticAnatomicalEntity.tsv b/src/curation/upheno-fillers/hp/hypoplasticAnatomicalEntity.tsv
new file mode 100644
index 00000000..116ea461
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/hypoplasticAnatomicalEntity.tsv
@@ -0,0 +1,177 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001075	http://purl.obolibrary.org/obo/UPHENO_0081079
+http://purl.obolibrary.org/obo/UBERON_0001235	http://purl.obolibrary.org/obo/UPHENO_0081268
+http://purl.obolibrary.org/obo/UBERON_0001752	http://purl.obolibrary.org/obo/UPHENO_0081269
+http://purl.obolibrary.org/obo/UBERON_0001476	http://purl.obolibrary.org/obo/UPHENO_0081270
+http://purl.obolibrary.org/obo/UBERON_0000388	http://purl.obolibrary.org/obo/UPHENO_0081081
+http://purl.obolibrary.org/obo/UBERON_0001630	http://purl.obolibrary.org/obo/UPHENO_0081082
+http://purl.obolibrary.org/obo/UBERON_0002048	http://purl.obolibrary.org/obo/UPHENO_0081083
+http://purl.obolibrary.org/obo/UBERON_0001236	http://purl.obolibrary.org/obo/UPHENO_0081271
+http://purl.obolibrary.org/obo/UBERON_0006767	http://purl.obolibrary.org/obo/UPHENO_0081272
+http://purl.obolibrary.org/obo/UBERON_0002567	http://purl.obolibrary.org/obo/UPHENO_0081273
+http://purl.obolibrary.org/obo/UBERON_0002446	http://purl.obolibrary.org/obo/UPHENO_0081274
+http://purl.obolibrary.org/obo/UBERON_0004106	http://purl.obolibrary.org/obo/UPHENO_0081275
+http://purl.obolibrary.org/obo/UBERON_0001473	http://purl.obolibrary.org/obo/UPHENO_0081276
+http://purl.obolibrary.org/obo/UBERON_0004621	http://purl.obolibrary.org/obo/UPHENO_0081277
+http://purl.obolibrary.org/obo/UBERON_0001076	http://purl.obolibrary.org/obo/UPHENO_0081278
+http://purl.obolibrary.org/obo/UBERON_0001112	http://purl.obolibrary.org/obo/UPHENO_0081279
+http://purl.obolibrary.org/obo/UBERON_0001870	http://purl.obolibrary.org/obo/UPHENO_0081280
+http://purl.obolibrary.org/obo/UBERON_0001078	http://purl.obolibrary.org/obo/UPHENO_0081281
+http://purl.obolibrary.org/obo/UBERON_0002046	http://purl.obolibrary.org/obo/UPHENO_0081084
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+http://purl.obolibrary.org/obo/UBERON_0001509	http://purl.obolibrary.org/obo/UPHENO_0081283
+http://purl.obolibrary.org/obo/UBERON_0001508	http://purl.obolibrary.org/obo/UPHENO_0081085
+http://purl.obolibrary.org/obo/UBERON_0003889	http://purl.obolibrary.org/obo/UPHENO_0081090
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+http://purl.obolibrary.org/obo/UBERON_0001908	http://purl.obolibrary.org/obo/UPHENO_0081285
+http://purl.obolibrary.org/obo/UBERON_0011277	http://purl.obolibrary.org/obo/UPHENO_0081286
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0081091
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+http://purl.obolibrary.org/obo/UBERON_0011932	http://purl.obolibrary.org/obo/UPHENO_0081288
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+http://purl.obolibrary.org/obo/UBERON_0004053	http://purl.obolibrary.org/obo/UPHENO_0081095
+http://purl.obolibrary.org/obo/CL_0000178	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001103	http://purl.obolibrary.org/obo/UPHENO_0081290
+http://purl.obolibrary.org/obo/UBERON_0002037	http://purl.obolibrary.org/obo/UPHENO_0081099
+http://purl.obolibrary.org/obo/UBERON_0004611	http://purl.obolibrary.org/obo/UPHENO_0081291
+http://purl.obolibrary.org/obo/UBERON_0002397	http://purl.obolibrary.org/obo/UPHENO_0081106
+http://purl.obolibrary.org/obo/UBERON_0008775	http://purl.obolibrary.org/obo/UPHENO_0081292
+http://purl.obolibrary.org/obo/UBERON_0001737	http://purl.obolibrary.org/obo/UPHENO_0081293
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+http://purl.obolibrary.org/obo/UBERON_0001691	http://purl.obolibrary.org/obo/UPHENO_0081119
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+http://purl.obolibrary.org/obo/UBERON_0002016	http://purl.obolibrary.org/obo/UPHENO_0081149
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+http://purl.obolibrary.org/obo/UBERON_0002378	http://purl.obolibrary.org/obo/UPHENO_0081307
+http://purl.obolibrary.org/obo/UBERON_0001443	http://purl.obolibrary.org/obo/UPHENO_0081308
+http://purl.obolibrary.org/obo/UBERON_0001446	http://purl.obolibrary.org/obo/UPHENO_0081309
+http://purl.obolibrary.org/obo/UBERON_0000995	http://purl.obolibrary.org/obo/UPHENO_0081155
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+http://purl.obolibrary.org/obo/UBERON_0000948	http://purl.obolibrary.org/obo/UPHENO_0081262
+http://purl.obolibrary.org/obo/UBERON_0000941	http://purl.obolibrary.org/obo/UPHENO_0081264
+http://purl.obolibrary.org/obo/UBERON_0011282	http://purl.obolibrary.org/obo/UPHENO_0081384
+http://purl.obolibrary.org/obo/UBERON_0000029	http://purl.obolibrary.org/obo/UPHENO_0081265
diff --git a/src/curation/upheno-fillers/hp/hypoplasticAnatomicalEntityInLocation.tsv b/src/curation/upheno-fillers/hp/hypoplasticAnatomicalEntityInLocation.tsv
new file mode 100644
index 00000000..48bab571
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/hypoplasticAnatomicalEntityInLocation.tsv
@@ -0,0 +1,5 @@
+anatomical_entity	location	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0001456	http://purl.obolibrary.org/obo/UPHENO_0081786
+http://purl.obolibrary.org/obo/UBERON_0001474	http://purl.obolibrary.org/obo/UBERON_0001456	http://purl.obolibrary.org/obo/UPHENO_0081788
+http://purl.obolibrary.org/obo/UBERON_0001015	http://purl.obolibrary.org/obo/UBERON_0004473	http://purl.obolibrary.org/obo/UPHENO_0081789
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0004473	http://purl.obolibrary.org/obo/UPHENO_0081791
diff --git a/src/curation/upheno-fillers/hp/increasedProportionOfCellTypeInLocation.tsv b/src/curation/upheno-fillers/hp/increasedProportionOfCellTypeInLocation.tsv
new file mode 100644
index 00000000..280e2c8f
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/increasedProportionOfCellTypeInLocation.tsv
@@ -0,0 +1,4 @@
+cell	location	defined_class
+http://purl.obolibrary.org/obo/CL_0000792	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0081425
+http://purl.obolibrary.org/obo/CL_0000000	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0081426
+http://purl.obolibrary.org/obo/CL_0000970	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0081428
diff --git a/src/curation/upheno-fillers/hp/increasedProportionOfCellTypeTowardsCellTypeInLocation.tsv b/src/curation/upheno-fillers/hp/increasedProportionOfCellTypeTowardsCellTypeInLocation.tsv
new file mode 100644
index 00000000..afce2f91
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/increasedProportionOfCellTypeTowardsCellTypeInLocation.tsv
@@ -0,0 +1,46 @@
+cell	compared_cell	location	defined_class
+http://purl.obolibrary.org/obo/CL_0001062	http://purl.obolibrary.org/obo/CL_0000084	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0080857
+http://purl.obolibrary.org/obo/CL_0000818	http://purl.obolibrary.org/obo/CL_0000236	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0080859
+http://purl.obolibrary.org/obo/CL_0000972	http://purl.obolibrary.org/obo/CL_0000000	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0080863
+http://purl.obolibrary.org/obo/CL_0000895	http://purl.obolibrary.org/obo/CL_0000000	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0080865
+http://purl.obolibrary.org/obo/CL_0000897	http://purl.obolibrary.org/obo/CL_0000084	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0080866
+http://purl.obolibrary.org/obo/CL_0000000	http://purl.obolibrary.org/obo/CL_0000236	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0080867
+http://purl.obolibrary.org/obo/CL_0000895	http://purl.obolibrary.org/obo/CL_0000084	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0080868
+http://purl.obolibrary.org/obo/CL_0001062	http://purl.obolibrary.org/obo/CL_0000000	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0080869
+http://purl.obolibrary.org/obo/CL_0000907	http://purl.obolibrary.org/obo/CL_0000084	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0080871
+http://purl.obolibrary.org/obo/CL_0000788	http://purl.obolibrary.org/obo/CL_0000000	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0080872
+http://purl.obolibrary.org/obo/CL_0000624	http://purl.obolibrary.org/obo/CL_0000000	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0080874
+http://purl.obolibrary.org/obo/CL_0000787	http://purl.obolibrary.org/obo/CL_0000000	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0080876
+http://purl.obolibrary.org/obo/CL_0000972	http://purl.obolibrary.org/obo/CL_0000236	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0080878
+http://purl.obolibrary.org/obo/CL_0000813	http://purl.obolibrary.org/obo/CL_0000236	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0080880
+http://purl.obolibrary.org/obo/CL_0000909	http://purl.obolibrary.org/obo/CL_0000000	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0080881
+http://purl.obolibrary.org/obo/CL_0000907	http://purl.obolibrary.org/obo/CL_0000000	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0080882
+http://purl.obolibrary.org/obo/CL_0000909	http://purl.obolibrary.org/obo/CL_0000084	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0080883
+http://purl.obolibrary.org/obo/CL_0000816	http://purl.obolibrary.org/obo/CL_0000236	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0080884
+http://purl.obolibrary.org/obo/CL_0000624	http://purl.obolibrary.org/obo/CL_0000084	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0080887
+http://purl.obolibrary.org/obo/CL_0000980	http://purl.obolibrary.org/obo/CL_0000000	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0080888
+http://purl.obolibrary.org/obo/CL_0000799	http://purl.obolibrary.org/obo/CL_0000000	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0080889
+http://purl.obolibrary.org/obo/CL_0000912	http://purl.obolibrary.org/obo/CL_0000000	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0080890
+http://purl.obolibrary.org/obo/CL_0011025	http://purl.obolibrary.org/obo/CL_0000084	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0080892
+http://purl.obolibrary.org/obo/CL_0000799	http://purl.obolibrary.org/obo/CL_0000084	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0080893
+http://purl.obolibrary.org/obo/CL_0000912	http://purl.obolibrary.org/obo/CL_0000084	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0080894
+http://purl.obolibrary.org/obo/CL_0000798	http://purl.obolibrary.org/obo/CL_0000000	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0080895
+http://purl.obolibrary.org/obo/CL_0000788	http://purl.obolibrary.org/obo/CL_0000236	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0080899
+http://purl.obolibrary.org/obo/CL_0000787	http://purl.obolibrary.org/obo/CL_0000236	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0080901
+http://purl.obolibrary.org/obo/CL_0011025	http://purl.obolibrary.org/obo/CL_0000000	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0080908
+http://purl.obolibrary.org/obo/CL_0001044	http://purl.obolibrary.org/obo/CL_0000000	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0080909
+http://purl.obolibrary.org/obo/CL_0000798	http://purl.obolibrary.org/obo/CL_0000084	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0080910
+http://purl.obolibrary.org/obo/CL_0000980	http://purl.obolibrary.org/obo/CL_0000236	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0080911
+http://purl.obolibrary.org/obo/CL_0001044	http://purl.obolibrary.org/obo/CL_0000084	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0080912
+http://purl.obolibrary.org/obo/CL_0000845	http://purl.obolibrary.org/obo/CL_0000000	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0080914
+http://purl.obolibrary.org/obo/CL_0000000	http://purl.obolibrary.org/obo/CL_0000084	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0080919
+http://purl.obolibrary.org/obo/CL_0001050	http://purl.obolibrary.org/obo/CL_0000000	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0080921
+http://purl.obolibrary.org/obo/CL_0001050	http://purl.obolibrary.org/obo/CL_0000084	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0080924
+http://purl.obolibrary.org/obo/CL_0000000	http://purl.obolibrary.org/obo/CL_0000000	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0080928
+http://purl.obolibrary.org/obo/CL_0000898	http://purl.obolibrary.org/obo/CL_0000000	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0080931
+http://purl.obolibrary.org/obo/CL_0000845	http://purl.obolibrary.org/obo/CL_0000236	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0080932
+http://purl.obolibrary.org/obo/CL_0000813	http://purl.obolibrary.org/obo/CL_0000000	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0080933
+http://purl.obolibrary.org/obo/CL_0000816	http://purl.obolibrary.org/obo/CL_0000000	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0080935
+http://purl.obolibrary.org/obo/CL_0000898	http://purl.obolibrary.org/obo/CL_0000084	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0080937
+http://purl.obolibrary.org/obo/CL_0000897	http://purl.obolibrary.org/obo/CL_0000000	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0080938
+http://purl.obolibrary.org/obo/CL_0000818	http://purl.obolibrary.org/obo/CL_0000000	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0080941
diff --git a/src/curation/upheno-fillers/hp/irregularMassDensityOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/hp/irregularMassDensityOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..b4989d33
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/irregularMassDensityOfAnatomicalEntity.tsv
@@ -0,0 +1,27 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0013749	http://purl.obolibrary.org/obo/UPHENO_0084659
+http://purl.obolibrary.org/obo/UBERON_0004385	http://purl.obolibrary.org/obo/UPHENO_0084660
+http://purl.obolibrary.org/obo/UBERON_0004384	http://purl.obolibrary.org/obo/UPHENO_0084661
+http://purl.obolibrary.org/obo/UBERON_0004382	http://purl.obolibrary.org/obo/UPHENO_0084662
+http://purl.obolibrary.org/obo/UBERON_0013748	http://purl.obolibrary.org/obo/UPHENO_0084663
+http://purl.obolibrary.org/obo/UBERON_0001435	http://purl.obolibrary.org/obo/UPHENO_0084664
+http://purl.obolibrary.org/obo/UBERON_0006864	http://purl.obolibrary.org/obo/UPHENO_0084665
+http://purl.obolibrary.org/obo/UBERON_0004387	http://purl.obolibrary.org/obo/UPHENO_0084666
+http://purl.obolibrary.org/obo/UBERON_0006863	http://purl.obolibrary.org/obo/UPHENO_0084667
+http://purl.obolibrary.org/obo/UBERON_0001447	http://purl.obolibrary.org/obo/UPHENO_0084668
+http://purl.obolibrary.org/obo/UBERON_0014386	http://purl.obolibrary.org/obo/UPHENO_0084669
+http://purl.obolibrary.org/obo/UBERON_0013750	http://purl.obolibrary.org/obo/UPHENO_0084670
+http://purl.obolibrary.org/obo/UBERON_0013751	http://purl.obolibrary.org/obo/UPHENO_0084671
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0084672
+http://purl.obolibrary.org/obo/UBERON_0016928	http://purl.obolibrary.org/obo/UPHENO_0084673
+http://purl.obolibrary.org/obo/UBERON_0002293	http://purl.obolibrary.org/obo/UPHENO_0084674
+http://purl.obolibrary.org/obo/UBERON_0004395	http://purl.obolibrary.org/obo/UPHENO_0084675
+http://purl.obolibrary.org/obo/UBERON_0004390	http://purl.obolibrary.org/obo/UPHENO_0084676
+http://purl.obolibrary.org/obo/UBERON_0004391	http://purl.obolibrary.org/obo/UPHENO_0084677
+http://purl.obolibrary.org/obo/UBERON_0006810	http://purl.obolibrary.org/obo/UPHENO_0084678
+http://purl.obolibrary.org/obo/UBERON_0008772	http://purl.obolibrary.org/obo/UPHENO_0084679
+http://purl.obolibrary.org/obo/UBERON_0004412	http://purl.obolibrary.org/obo/UPHENO_0084680
+http://purl.obolibrary.org/obo/UBERON_0001437	http://purl.obolibrary.org/obo/UPHENO_0084681
+http://purl.obolibrary.org/obo/UBERON_0004406	http://purl.obolibrary.org/obo/UPHENO_0084682
+http://purl.obolibrary.org/obo/UBERON_0001438	http://purl.obolibrary.org/obo/UPHENO_0084683
+http://purl.obolibrary.org/obo/UBERON_0014437	http://purl.obolibrary.org/obo/UPHENO_0084684
diff --git a/src/curation/upheno-fillers/hp/ivoryAnatomicalEntity.tsv b/src/curation/upheno-fillers/hp/ivoryAnatomicalEntity.tsv
new file mode 100644
index 00000000..b7952af8
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/ivoryAnatomicalEntity.tsv
@@ -0,0 +1,7 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0084429
+http://purl.obolibrary.org/obo/UBERON_0004395	http://purl.obolibrary.org/obo/UPHENO_0084430
+http://purl.obolibrary.org/obo/UBERON_0001437	http://purl.obolibrary.org/obo/UPHENO_0084431
+http://purl.obolibrary.org/obo/UBERON_0004390	http://purl.obolibrary.org/obo/UPHENO_0084432
+http://purl.obolibrary.org/obo/UBERON_0004391	http://purl.obolibrary.org/obo/UPHENO_0084433
+http://purl.obolibrary.org/obo/UBERON_0004387	http://purl.obolibrary.org/obo/UPHENO_0084434
diff --git a/src/curation/upheno-fillers/hp/malformedAnatomicalEntity.tsv b/src/curation/upheno-fillers/hp/malformedAnatomicalEntity.tsv
new file mode 100644
index 00000000..c9348a29
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/malformedAnatomicalEntity.tsv
@@ -0,0 +1,10 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0071309
+http://purl.obolibrary.org/obo/UBERON_0008788	http://purl.obolibrary.org/obo/UPHENO_0071321
+http://purl.obolibrary.org/obo/UBERON_0001638	http://purl.obolibrary.org/obo/UPHENO_0071349
+http://purl.obolibrary.org/obo/UBERON_0001739	http://purl.obolibrary.org/obo/UPHENO_0071350
+http://purl.obolibrary.org/obo/UBERON_0001844	http://purl.obolibrary.org/obo/UPHENO_0071333
+http://purl.obolibrary.org/obo/UBERON_0001766	http://purl.obolibrary.org/obo/UPHENO_0071334
+http://purl.obolibrary.org/obo/UBERON_0010230	http://purl.obolibrary.org/obo/UPHENO_0071353
+http://purl.obolibrary.org/obo/UBERON_0002037	http://purl.obolibrary.org/obo/UPHENO_0071344
+http://purl.obolibrary.org/obo/UBERON_0001850	http://purl.obolibrary.org/obo/UPHENO_0071329
diff --git a/src/curation/upheno-fillers/hp/malformedAnatomicalEntityByType.tsv b/src/curation/upheno-fillers/hp/malformedAnatomicalEntityByType.tsv
new file mode 100644
index 00000000..cf7b23b0
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/malformedAnatomicalEntityByType.tsv
@@ -0,0 +1 @@
+anatomical_entity	malformed	defined_class
diff --git a/src/curation/upheno-fillers/hp/mislocalisedAnatomicalEntity.tsv b/src/curation/upheno-fillers/hp/mislocalisedAnatomicalEntity.tsv
new file mode 100644
index 00000000..b20d3a60
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/mislocalisedAnatomicalEntity.tsv
@@ -0,0 +1,15 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0053580
+http://purl.obolibrary.org/obo/UBERON_0002196	http://purl.obolibrary.org/obo/UPHENO_0053583
+http://purl.obolibrary.org/obo/UBERON_0001245	http://purl.obolibrary.org/obo/UPHENO_0053661
+http://purl.obolibrary.org/obo/UBERON_0002106	http://purl.obolibrary.org/obo/UPHENO_0053616
+http://purl.obolibrary.org/obo/UBERON_0002369	http://purl.obolibrary.org/obo/UPHENO_0053568
+http://purl.obolibrary.org/obo/UBERON_0002198	http://purl.obolibrary.org/obo/UPHENO_0053586
+http://purl.obolibrary.org/obo/UBERON_0000473	http://purl.obolibrary.org/obo/UPHENO_0053644
+http://purl.obolibrary.org/obo/UBERON_0002113	http://purl.obolibrary.org/obo/UPHENO_0053588
+http://purl.obolibrary.org/obo/UBERON_0001771	http://purl.obolibrary.org/obo/UPHENO_0053660
+http://purl.obolibrary.org/obo/UBERON_0002046	http://purl.obolibrary.org/obo/UPHENO_0053576
+http://purl.obolibrary.org/obo/UBERON_0002107	http://purl.obolibrary.org/obo/UPHENO_0053656
+http://purl.obolibrary.org/obo/UBERON_0000965	http://purl.obolibrary.org/obo/UPHENO_0053594
+http://purl.obolibrary.org/obo/UBERON_0001702	http://purl.obolibrary.org/obo/UPHENO_0053654
+http://purl.obolibrary.org/obo/CL_0002319	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/hp/mislocalisedAnatomicalEntityInLocation.tsv b/src/curation/upheno-fillers/hp/mislocalisedAnatomicalEntityInLocation.tsv
new file mode 100644
index 00000000..a987175d
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/mislocalisedAnatomicalEntityInLocation.tsv
@@ -0,0 +1,5 @@
+anatomical_entity	location	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0001264	http://purl.obolibrary.org/obo/UPHENO_0081752
+http://purl.obolibrary.org/obo/UBERON_0000479	http://purl.obolibrary.org/obo/UBERON_0002370	http://purl.obolibrary.org/obo/UPHENO_0081754
+http://purl.obolibrary.org/obo/UBERON_0000479	http://purl.obolibrary.org/obo/UBERON_0001264	http://purl.obolibrary.org/obo/UPHENO_0081756
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0002370	http://purl.obolibrary.org/obo/UPHENO_0081757
diff --git a/src/curation/upheno-fillers/hp/necroticAnatomicalEntity.tsv b/src/curation/upheno-fillers/hp/necroticAnatomicalEntity.tsv
new file mode 100644
index 00000000..de67cac7
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/necroticAnatomicalEntity.tsv
@@ -0,0 +1,3 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0081698
+http://purl.obolibrary.org/obo/UBERON_0001225	http://purl.obolibrary.org/obo/UPHENO_0081699
diff --git a/src/curation/upheno-fillers/hp/non-functionalAnatomicalEntity.tsv b/src/curation/upheno-fillers/hp/non-functionalAnatomicalEntity.tsv
new file mode 100644
index 00000000..e48865d6
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/non-functionalAnatomicalEntity.tsv
@@ -0,0 +1,7 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0004681	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001711	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002107	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001004	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002113	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/hp/obstructedAnatomicalEntity.tsv b/src/curation/upheno-fillers/hp/obstructedAnatomicalEntity.tsv
new file mode 100644
index 00000000..e18c2314
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/obstructedAnatomicalEntity.tsv
@@ -0,0 +1,8 @@
+anatomical_space	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0000160	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001737	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001173	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001850	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0009973	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0000056	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/hp/paralysedAnatomicalEntity.tsv b/src/curation/upheno-fillers/hp/paralysedAnatomicalEntity.tsv
new file mode 100644
index 00000000..e6fd2f65
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/paralysedAnatomicalEntity.tsv
@@ -0,0 +1,7 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0081700
+http://purl.obolibrary.org/obo/UBERON_0003706	http://purl.obolibrary.org/obo/UPHENO_0081708
+http://purl.obolibrary.org/obo/UBERON_0001601	http://purl.obolibrary.org/obo/UPHENO_0081701
+http://purl.obolibrary.org/obo/UBERON_0001785	http://purl.obolibrary.org/obo/UPHENO_0081709
+http://purl.obolibrary.org/obo/UBERON_0001103	http://purl.obolibrary.org/obo/UPHENO_0081710
+http://purl.obolibrary.org/obo/UBERON_0001577	http://purl.obolibrary.org/obo/UPHENO_0081703
diff --git a/src/curation/upheno-fillers/hp/perforateAnatomicalEntity.tsv b/src/curation/upheno-fillers/hp/perforateAnatomicalEntity.tsv
new file mode 100644
index 00000000..72b7b443
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/perforateAnatomicalEntity.tsv
@@ -0,0 +1,5 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002085	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0000964	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002068	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/hp/prematureClosureOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/hp/prematureClosureOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..8d53079e
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/prematureClosureOfAnatomicalEntity.tsv
@@ -0,0 +1,9 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0084631
+http://purl.obolibrary.org/obo/UBERON_0002492	http://purl.obolibrary.org/obo/UPHENO_0084632
+http://purl.obolibrary.org/obo/UBERON_0002491	http://purl.obolibrary.org/obo/UPHENO_0084633
+http://purl.obolibrary.org/obo/UBERON_0006683	http://purl.obolibrary.org/obo/UPHENO_0084644
+http://purl.obolibrary.org/obo/UBERON_0002489	http://purl.obolibrary.org/obo/UPHENO_0084635
+http://purl.obolibrary.org/obo/UBERON_0001697	http://purl.obolibrary.org/obo/UPHENO_0084645
+http://purl.obolibrary.org/obo/UBERON_0000982	http://purl.obolibrary.org/obo/UPHENO_0084646
+http://purl.obolibrary.org/obo/UBERON_0002510	http://purl.obolibrary.org/obo/UPHENO_0084647
diff --git a/src/curation/upheno-fillers/hp/spatialDeviationOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/hp/spatialDeviationOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..90779b0f
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/spatialDeviationOfAnatomicalEntity.tsv
@@ -0,0 +1,14 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0003623	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0003634	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001466	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002389	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0003624	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0003635	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0003632	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0003622	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0003633	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0003631	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001463	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0003625	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/hp/wrinkledAnatomicalEntity.tsv b/src/curation/upheno-fillers/hp/wrinkledAnatomicalEntity.tsv
new file mode 100644
index 00000000..535da59e
--- /dev/null
+++ b/src/curation/upheno-fillers/hp/wrinkledAnatomicalEntity.tsv
@@ -0,0 +1,6 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0016462	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002097	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0013777	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001456	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/mgpo/abnormalLevelOfChemicalEntity.tsv b/src/curation/upheno-fillers/mgpo/abnormalLevelOfChemicalEntity.tsv
new file mode 100644
index 00000000..8077cb3e
--- /dev/null
+++ b/src/curation/upheno-fillers/mgpo/abnormalLevelOfChemicalEntity.tsv
@@ -0,0 +1,5 @@
+chemical_entity	defined_class
+http://purl.obolibrary.org/obo/CHEBI_24431	http://purl.obolibrary.org/obo/UPHENO_0046284
+http://purl.obolibrary.org/obo/CHEBI_35258	http://purl.obolibrary.org/obo/UPHENO_0081780
+http://purl.obolibrary.org/obo/CHEBI_24396	http://purl.obolibrary.org/obo/UPHENO_0081781
+http://purl.obolibrary.org/obo/CHEBI_17089	http://purl.obolibrary.org/obo/UPHENO_0081782
diff --git a/src/curation/upheno-fillers/mgpo/abnormalLevelOfChemicalEntityInLocation.tsv b/src/curation/upheno-fillers/mgpo/abnormalLevelOfChemicalEntityInLocation.tsv
new file mode 100644
index 00000000..85f54a48
--- /dev/null
+++ b/src/curation/upheno-fillers/mgpo/abnormalLevelOfChemicalEntityInLocation.tsv
@@ -0,0 +1,2 @@
+chemical_entity	location	defined_class
+http://purl.obolibrary.org/obo/CHEBI_24431	http://purl.obolibrary.org/obo/UBERON_0001088	http://purl.obolibrary.org/obo/UPHENO_0051686
diff --git a/src/curation/upheno-fillers/mgpo/abnormalMolecularFunction.tsv b/src/curation/upheno-fillers/mgpo/abnormalMolecularFunction.tsv
new file mode 100644
index 00000000..d99f6f93
--- /dev/null
+++ b/src/curation/upheno-fillers/mgpo/abnormalMolecularFunction.tsv
@@ -0,0 +1,5 @@
+molecular_function	defined_class
+http://purl.obolibrary.org/obo/GO_0016798	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0003674	http://purl.obolibrary.org/obo/UPHENO_0031743
+http://purl.obolibrary.org/obo/GO_0004576	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0016757	http://purl.obolibrary.org/obo/UPHENO_0031744
diff --git a/src/curation/upheno-fillers/mgpo/abnormallyDecreasedLevelOfChemicalEntity.tsv b/src/curation/upheno-fillers/mgpo/abnormallyDecreasedLevelOfChemicalEntity.tsv
new file mode 100644
index 00000000..74b01823
--- /dev/null
+++ b/src/curation/upheno-fillers/mgpo/abnormallyDecreasedLevelOfChemicalEntity.tsv
@@ -0,0 +1,2 @@
+chemical_entity	defined_class
+http://purl.obolibrary.org/obo/CHEBI_24431	http://purl.obolibrary.org/obo/UPHENO_0066739
diff --git a/src/curation/upheno-fillers/mgpo/abnormallyDecreasedLevelOfChemicalEntityInLocation.tsv b/src/curation/upheno-fillers/mgpo/abnormallyDecreasedLevelOfChemicalEntityInLocation.tsv
new file mode 100644
index 00000000..771bd0bb
--- /dev/null
+++ b/src/curation/upheno-fillers/mgpo/abnormallyDecreasedLevelOfChemicalEntityInLocation.tsv
@@ -0,0 +1,2 @@
+chemical_entity	location	defined_class
+http://purl.obolibrary.org/obo/CHEBI_24431	http://purl.obolibrary.org/obo/UBERON_0001088	http://purl.obolibrary.org/obo/UPHENO_0034235
diff --git a/src/curation/upheno-fillers/mgpo/abnormallyIncreasedLevelOfChemicalEntity.tsv b/src/curation/upheno-fillers/mgpo/abnormallyIncreasedLevelOfChemicalEntity.tsv
new file mode 100644
index 00000000..33647483
--- /dev/null
+++ b/src/curation/upheno-fillers/mgpo/abnormallyIncreasedLevelOfChemicalEntity.tsv
@@ -0,0 +1,2 @@
+chemical_entity	defined_class
+http://purl.obolibrary.org/obo/CHEBI_24431	http://purl.obolibrary.org/obo/UPHENO_0048707
diff --git a/src/curation/upheno-fillers/mgpo/abnormallyIncreasedLevelOfChemicalEntityInLocation.tsv b/src/curation/upheno-fillers/mgpo/abnormallyIncreasedLevelOfChemicalEntityInLocation.tsv
new file mode 100644
index 00000000..6252521f
--- /dev/null
+++ b/src/curation/upheno-fillers/mgpo/abnormallyIncreasedLevelOfChemicalEntityInLocation.tsv
@@ -0,0 +1,4 @@
+chemical_entity	location	defined_class
+http://purl.obolibrary.org/obo/CHEBI_50699	http://purl.obolibrary.org/obo/UBERON_0001088	http://purl.obolibrary.org/obo/UPHENO_0068589
+http://purl.obolibrary.org/obo/CHEBI_24431	http://purl.obolibrary.org/obo/UBERON_0001088	http://purl.obolibrary.org/obo/UPHENO_0068110
+http://purl.obolibrary.org/obo/CHEBI_35381	http://purl.obolibrary.org/obo/UBERON_0001088	http://purl.obolibrary.org/obo/UPHENO_0080658
diff --git a/src/curation/upheno-fillers/mp/abnormalAbsenceOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/mp/abnormalAbsenceOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..59bc526f
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormalAbsenceOfAnatomicalEntity.tsv
@@ -0,0 +1,544 @@
+anatomical_entity	defined_class
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+http://purl.obolibrary.org/obo/UBERON_0018231	http://purl.obolibrary.org/obo/UPHENO_0008846
+http://purl.obolibrary.org/obo/UBERON_0001911	http://purl.obolibrary.org/obo/UPHENO_0081414
+http://purl.obolibrary.org/obo/UBERON_0010510	http://purl.obolibrary.org/obo/UPHENO_0008847
+http://purl.obolibrary.org/obo/UBERON_0019325	http://purl.obolibrary.org/obo/UPHENO_0008848
diff --git a/src/curation/upheno-fillers/mp/abnormalAbsenceOfAnatomicalEntityInLocation.tsv b/src/curation/upheno-fillers/mp/abnormalAbsenceOfAnatomicalEntityInLocation.tsv
new file mode 100644
index 00000000..2a44f477
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormalAbsenceOfAnatomicalEntityInLocation.tsv
@@ -0,0 +1,306 @@
+anatomical_entity	location	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0004347	http://purl.obolibrary.org/obo/UPHENO_0026078
+http://purl.obolibrary.org/obo/UBERON_0001043	http://purl.obolibrary.org/obo/UBERON_0005409	http://purl.obolibrary.org/obo/UPHENO_0025097
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0002046	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0010380	http://purl.obolibrary.org/obo/UBERON_0002005	http://purl.obolibrary.org/obo/UPHENO_0026602
+http://purl.obolibrary.org/obo/UBERON_0003988	http://purl.obolibrary.org/obo/UBERON_0002125	http://purl.obolibrary.org/obo/UPHENO_0026605
+http://purl.obolibrary.org/obo/UBERON_0001943	http://purl.obolibrary.org/obo/UBERON_0001891	http://purl.obolibrary.org/obo/UPHENO_0026607
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0003126	http://purl.obolibrary.org/obo/UPHENO_0025589
+http://purl.obolibrary.org/obo/UBERON_0002533	http://purl.obolibrary.org/obo/UBERON_0000468	http://purl.obolibrary.org/obo/UPHENO_0026609
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0004453	http://purl.obolibrary.org/obo/UPHENO_0025593
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0003128	http://purl.obolibrary.org/obo/UPHENO_0025594
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0008933	http://purl.obolibrary.org/obo/UPHENO_0025111
+http://purl.obolibrary.org/obo/CL_0000635	http://purl.obolibrary.org/obo/UBERON_0002227	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001105	http://purl.obolibrary.org/obo/UBERON_0001467	http://purl.obolibrary.org/obo/UPHENO_0026624
+http://purl.obolibrary.org/obo/UBERON_0003881	http://purl.obolibrary.org/obo/UBERON_0003876	http://purl.obolibrary.org/obo/UPHENO_0025124
+http://purl.obolibrary.org/obo/UBERON_0003883	http://purl.obolibrary.org/obo/UBERON_0003876	http://purl.obolibrary.org/obo/UPHENO_0025126
+http://purl.obolibrary.org/obo/UBERON_0001691	http://purl.obolibrary.org/obo/UBERON_0000033	http://purl.obolibrary.org/obo/UPHENO_0026628
+http://purl.obolibrary.org/obo/UBERON_0003882	http://purl.obolibrary.org/obo/UBERON_0003876	http://purl.obolibrary.org/obo/UPHENO_0025127
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0007833	http://purl.obolibrary.org/obo/UPHENO_0026117
+http://purl.obolibrary.org/obo/UBERON_0001860	http://purl.obolibrary.org/obo/UBERON_0001846	http://purl.obolibrary.org/obo/UPHENO_0025130
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0001173	http://purl.obolibrary.org/obo/UPHENO_0026633
+http://purl.obolibrary.org/obo/UBERON_0001424	http://purl.obolibrary.org/obo/UBERON_0002102	http://purl.obolibrary.org/obo/UPHENO_0026126
+http://purl.obolibrary.org/obo/UBERON_0001423	http://purl.obolibrary.org/obo/UBERON_0002102	http://purl.obolibrary.org/obo/UPHENO_0026128
+http://purl.obolibrary.org/obo/UBERON_0003884	http://purl.obolibrary.org/obo/UBERON_0003876	http://purl.obolibrary.org/obo/UPHENO_0025138
+http://purl.obolibrary.org/obo/UBERON_0001676	http://purl.obolibrary.org/obo/UBERON_0003128	http://purl.obolibrary.org/obo/UPHENO_0026635
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0002129	http://purl.obolibrary.org/obo/UPHENO_0026136
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0005409	http://purl.obolibrary.org/obo/UPHENO_0025161
+http://purl.obolibrary.org/obo/UBERON_0003604	http://purl.obolibrary.org/obo/UBERON_0003126	http://purl.obolibrary.org/obo/UPHENO_0025642
+http://purl.obolibrary.org/obo/UBERON_0001435	http://purl.obolibrary.org/obo/UBERON_0002101	http://purl.obolibrary.org/obo/UPHENO_0026144
+http://purl.obolibrary.org/obo/CL_0000695	http://purl.obolibrary.org/obo/UBERON_0010403	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0002369	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002397	http://purl.obolibrary.org/obo/UBERON_0002244	http://purl.obolibrary.org/obo/UPHENO_0025653
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0002005	http://purl.obolibrary.org/obo/UPHENO_0026658
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0003216	http://purl.obolibrary.org/obo/UPHENO_0025170
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0002125	http://purl.obolibrary.org/obo/UPHENO_0026153
+http://purl.obolibrary.org/obo/UBERON_0000440	http://purl.obolibrary.org/obo/UBERON_0002349	http://purl.obolibrary.org/obo/UPHENO_0025662
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0002244	http://purl.obolibrary.org/obo/UPHENO_0025664
+http://purl.obolibrary.org/obo/UBERON_0001818	http://purl.obolibrary.org/obo/UBERON_0001711	http://purl.obolibrary.org/obo/UPHENO_0025674
+http://purl.obolibrary.org/obo/CL_0000817	http://purl.obolibrary.org/obo/UBERON_0002405	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001885	http://purl.obolibrary.org/obo/UBERON_0002421	http://purl.obolibrary.org/obo/UPHENO_0026666
+http://purl.obolibrary.org/obo/UBERON_0005600	http://purl.obolibrary.org/obo/UBERON_0007833	http://purl.obolibrary.org/obo/UPHENO_0025186
+http://purl.obolibrary.org/obo/UBERON_0001687	http://purl.obolibrary.org/obo/UBERON_0001756	http://purl.obolibrary.org/obo/UPHENO_0026669
+http://purl.obolibrary.org/obo/UBERON_0001985	http://purl.obolibrary.org/obo/UBERON_0000964	http://purl.obolibrary.org/obo/UPHENO_0026670
+http://purl.obolibrary.org/obo/UBERON_0001954	http://purl.obolibrary.org/obo/UBERON_0000955	http://purl.obolibrary.org/obo/UPHENO_0026671
+http://purl.obolibrary.org/obo/UBERON_0001688	http://purl.obolibrary.org/obo/UBERON_0001756	http://purl.obolibrary.org/obo/UPHENO_0026672
+http://purl.obolibrary.org/obo/UBERON_0010388	http://purl.obolibrary.org/obo/UBERON_0001443	http://purl.obolibrary.org/obo/UPHENO_0025192
+http://purl.obolibrary.org/obo/UBERON_0001686	http://purl.obolibrary.org/obo/UBERON_0001756	http://purl.obolibrary.org/obo/UPHENO_0026673
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000540	http://purl.obolibrary.org/obo/UBERON_0000956	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001044	http://purl.obolibrary.org/obo/UBERON_0002330	http://purl.obolibrary.org/obo/UPHENO_0025194
+http://purl.obolibrary.org/obo/UBERON_0001702	http://purl.obolibrary.org/obo/UBERON_0001711	http://purl.obolibrary.org/obo/UPHENO_0026167
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0002108	http://purl.obolibrary.org/obo/UPHENO_0026169
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0002349	http://purl.obolibrary.org/obo/UPHENO_0025196
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0002113	http://purl.obolibrary.org/obo/UPHENO_0026170
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0002227	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0001017	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0001016	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000598	http://purl.obolibrary.org/obo/UBERON_0000956	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001844	http://purl.obolibrary.org/obo/UBERON_0001846	http://purl.obolibrary.org/obo/UPHENO_0025206
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0001132	http://purl.obolibrary.org/obo/UPHENO_0026681
+http://purl.obolibrary.org/obo/UBERON_0001577	http://purl.obolibrary.org/obo/UBERON_0000468	http://purl.obolibrary.org/obo/UPHENO_0025207
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0002103	http://purl.obolibrary.org/obo/UPHENO_0026177
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0001008	http://purl.obolibrary.org/obo/UPHENO_0025211
+http://purl.obolibrary.org/obo/CL_0000540	http://purl.obolibrary.org/obo/UBERON_0001954	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0002102	http://purl.obolibrary.org/obo/UPHENO_0026181
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0000165	http://purl.obolibrary.org/obo/UPHENO_0025212
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0001255	http://purl.obolibrary.org/obo/UPHENO_0026182
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0002101	http://purl.obolibrary.org/obo/UPHENO_0026183
+http://purl.obolibrary.org/obo/UBERON_0000375	http://purl.obolibrary.org/obo/UBERON_0001645	http://purl.obolibrary.org/obo/UPHENO_0025213
+http://purl.obolibrary.org/obo/CL_0000815	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0004086	http://purl.obolibrary.org/obo/UBERON_0003947	http://purl.obolibrary.org/obo/UPHENO_0025693
+http://purl.obolibrary.org/obo/UBERON_0001854	http://purl.obolibrary.org/obo/UBERON_0001862	http://purl.obolibrary.org/obo/UPHENO_0025214
+http://purl.obolibrary.org/obo/UBERON_0002314	http://purl.obolibrary.org/obo/UBERON_0001891	http://purl.obolibrary.org/obo/UPHENO_0025217
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0001130	http://purl.obolibrary.org/obo/UPHENO_0026689
+http://purl.obolibrary.org/obo/UBERON_0002824	http://purl.obolibrary.org/obo/UBERON_0002827	http://purl.obolibrary.org/obo/UPHENO_0026185
+http://purl.obolibrary.org/obo/GO_0060091	http://purl.obolibrary.org/obo/CL_0000589	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0000160	http://purl.obolibrary.org/obo/UPHENO_0025222
+http://purl.obolibrary.org/obo/UBERON_0002110	http://purl.obolibrary.org/obo/UBERON_0001173	http://purl.obolibrary.org/obo/UPHENO_0025697
+http://purl.obolibrary.org/obo/GO_0042588	http://purl.obolibrary.org/obo/CL_0002064	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0001241	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0002330	http://purl.obolibrary.org/obo/UPHENO_0025226
+http://purl.obolibrary.org/obo/UBERON_0004727	http://purl.obolibrary.org/obo/UBERON_0001648	http://purl.obolibrary.org/obo/UPHENO_0025228
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0001003	http://purl.obolibrary.org/obo/UPHENO_0025229
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0003426	http://purl.obolibrary.org/obo/UPHENO_0026189
+http://purl.obolibrary.org/obo/UBERON_0002374	http://purl.obolibrary.org/obo/UBERON_0004453	http://purl.obolibrary.org/obo/UPHENO_0025701
+http://purl.obolibrary.org/obo/CL_0002082	http://purl.obolibrary.org/obo/UBERON_0002369	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0007247	http://purl.obolibrary.org/obo/UBERON_0000988	http://purl.obolibrary.org/obo/UPHENO_0026701
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0000033	http://purl.obolibrary.org/obo/UPHENO_0025708
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/CL_0000746	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001077	http://purl.obolibrary.org/obo/UBERON_0001130	http://purl.obolibrary.org/obo/UPHENO_0026710
+http://purl.obolibrary.org/obo/UBERON_0001076	http://purl.obolibrary.org/obo/UBERON_0001130	http://purl.obolibrary.org/obo/UPHENO_0026711
+http://purl.obolibrary.org/obo/UBERON_0001075	http://purl.obolibrary.org/obo/UBERON_0001130	http://purl.obolibrary.org/obo/UPHENO_0026712
+http://purl.obolibrary.org/obo/UBERON_0002227	http://purl.obolibrary.org/obo/UBERON_0001855	http://purl.obolibrary.org/obo/UPHENO_0026196
+http://purl.obolibrary.org/obo/UBERON_0001817	http://purl.obolibrary.org/obo/UBERON_0002330	http://purl.obolibrary.org/obo/UPHENO_0025250
+http://purl.obolibrary.org/obo/UBERON_0000979	http://purl.obolibrary.org/obo/UBERON_0002103	http://purl.obolibrary.org/obo/UPHENO_0026210
+http://purl.obolibrary.org/obo/CL_0000584	http://purl.obolibrary.org/obo/UBERON_0000160	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0000976	http://purl.obolibrary.org/obo/UBERON_0002102	http://purl.obolibrary.org/obo/UPHENO_0026214
+http://purl.obolibrary.org/obo/UBERON_0001847	http://purl.obolibrary.org/obo/UBERON_0001690	http://purl.obolibrary.org/obo/UPHENO_0026224
+http://purl.obolibrary.org/obo/UBERON_0010402	http://purl.obolibrary.org/obo/UBERON_0001003	http://purl.obolibrary.org/obo/UPHENO_0026727
+http://purl.obolibrary.org/obo/UBERON_0000949	http://purl.obolibrary.org/obo/UBERON_0001132	http://purl.obolibrary.org/obo/UPHENO_0026728
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/CL_0002064	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000623	http://purl.obolibrary.org/obo/UBERON_0002405	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0000056	http://purl.obolibrary.org/obo/UBERON_0005179	http://purl.obolibrary.org/obo/UPHENO_0025270
+http://purl.obolibrary.org/obo/GO_0042599	http://purl.obolibrary.org/obo/CL_0000362	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0031514	http://purl.obolibrary.org/obo/CL_0002368	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002498	http://purl.obolibrary.org/obo/UBERON_0000976	http://purl.obolibrary.org/obo/UPHENO_0025273
+http://purl.obolibrary.org/obo/UBERON_0010415	http://purl.obolibrary.org/obo/UBERON_0008933	http://purl.obolibrary.org/obo/UPHENO_0026733
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0000966	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000128	http://purl.obolibrary.org/obo/UBERON_0001017	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0010409	http://purl.obolibrary.org/obo/UPHENO_0025284
+http://purl.obolibrary.org/obo/UBERON_0001275	http://purl.obolibrary.org/obo/UBERON_0005179	http://purl.obolibrary.org/obo/UPHENO_0025755
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0005366	http://purl.obolibrary.org/obo/UPHENO_0025756
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0010403	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001273	http://purl.obolibrary.org/obo/UBERON_0005179	http://purl.obolibrary.org/obo/UPHENO_0025757
+http://purl.obolibrary.org/obo/UBERON_0001703	http://purl.obolibrary.org/obo/UBERON_0003128	http://purl.obolibrary.org/obo/UPHENO_0026256
+http://purl.obolibrary.org/obo/UBERON_0004078	http://purl.obolibrary.org/obo/UBERON_0004720	http://purl.obolibrary.org/obo/UPHENO_0026266
+http://purl.obolibrary.org/obo/UBERON_0001679	http://purl.obolibrary.org/obo/UBERON_0003128	http://purl.obolibrary.org/obo/UPHENO_0026745
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0002080	http://purl.obolibrary.org/obo/UPHENO_0026746
+http://purl.obolibrary.org/obo/CL_0000700	http://purl.obolibrary.org/obo/UBERON_0001016	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001695	http://purl.obolibrary.org/obo/UBERON_0003128	http://purl.obolibrary.org/obo/UPHENO_0026747
+http://purl.obolibrary.org/obo/UBERON_0004082	http://purl.obolibrary.org/obo/UBERON_0004720	http://purl.obolibrary.org/obo/UPHENO_0026289
+http://purl.obolibrary.org/obo/UBERON_0001211	http://purl.obolibrary.org/obo/UBERON_0000160	http://purl.obolibrary.org/obo/UPHENO_0026290
+http://purl.obolibrary.org/obo/UBERON_0001718	http://purl.obolibrary.org/obo/UBERON_0001891	http://purl.obolibrary.org/obo/UPHENO_0025783
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+http://purl.obolibrary.org/obo/UBERON_0000964	http://purl.obolibrary.org/obo/UBERON_0001801	http://purl.obolibrary.org/obo/UPHENO_0026005
+http://purl.obolibrary.org/obo/UBERON_0003451	http://purl.obolibrary.org/obo/UBERON_0000165	http://purl.obolibrary.org/obo/UPHENO_0026989
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0002412	http://purl.obolibrary.org/obo/UPHENO_0025501
+http://purl.obolibrary.org/obo/UBERON_0001779	http://purl.obolibrary.org/obo/UBERON_0001769	http://purl.obolibrary.org/obo/UPHENO_0026991
+http://purl.obolibrary.org/obo/UBERON_0001689	http://purl.obolibrary.org/obo/UBERON_0001756	http://purl.obolibrary.org/obo/UPHENO_0025502
+http://purl.obolibrary.org/obo/CL_0000598	http://purl.obolibrary.org/obo/UBERON_0001954	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0001443	http://purl.obolibrary.org/obo/UPHENO_0026008
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0002405	http://purl.obolibrary.org/obo/UPHENO_0025506
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0000468	http://purl.obolibrary.org/obo/UPHENO_0026506
+http://purl.obolibrary.org/obo/UBERON_0003450	http://purl.obolibrary.org/obo/UBERON_0000165	http://purl.obolibrary.org/obo/UPHENO_0026993
+http://purl.obolibrary.org/obo/UBERON_0001066	http://purl.obolibrary.org/obo/UBERON_0002412	http://purl.obolibrary.org/obo/UPHENO_0025512
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0001434	http://purl.obolibrary.org/obo/UPHENO_0026023
+http://purl.obolibrary.org/obo/CL_0000748	http://purl.obolibrary.org/obo/UBERON_0000966	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0030057	http://purl.obolibrary.org/obo/CL_0000746	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001775	http://purl.obolibrary.org/obo/UBERON_0011892	http://purl.obolibrary.org/obo/UPHENO_0025515
+http://purl.obolibrary.org/obo/UBERON_0007812	http://purl.obolibrary.org/obo/UBERON_0000468	http://purl.obolibrary.org/obo/UPHENO_0025517
+http://purl.obolibrary.org/obo/UBERON_0000007	http://purl.obolibrary.org/obo/UBERON_0000949	http://purl.obolibrary.org/obo/UPHENO_0026536
+http://purl.obolibrary.org/obo/UBERON_0001759	http://purl.obolibrary.org/obo/UBERON_0001785	http://purl.obolibrary.org/obo/UPHENO_0027023
+http://purl.obolibrary.org/obo/UBERON_0006849	http://purl.obolibrary.org/obo/UBERON_0001467	http://purl.obolibrary.org/obo/UPHENO_0025524
+http://purl.obolibrary.org/obo/CL_0000166	http://purl.obolibrary.org/obo/UBERON_0002369	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0003128	http://purl.obolibrary.org/obo/UBERON_0001434	http://purl.obolibrary.org/obo/UPHENO_0026540
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0010011	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0001785	http://purl.obolibrary.org/obo/UPHENO_0026545
+http://purl.obolibrary.org/obo/UBERON_0005363	http://purl.obolibrary.org/obo/UBERON_0000033	http://purl.obolibrary.org/obo/UPHENO_0027030
+http://purl.obolibrary.org/obo/UBERON_0005360	http://purl.obolibrary.org/obo/UBERON_0000033	http://purl.obolibrary.org/obo/UPHENO_0027034
+http://purl.obolibrary.org/obo/UBERON_0001647	http://purl.obolibrary.org/obo/UBERON_0001785	http://purl.obolibrary.org/obo/UPHENO_0025530
+http://purl.obolibrary.org/obo/UBERON_0003718	http://purl.obolibrary.org/obo/UBERON_0001630	http://purl.obolibrary.org/obo/UPHENO_0026551
+http://purl.obolibrary.org/obo/UBERON_0001648	http://purl.obolibrary.org/obo/UBERON_0001785	http://purl.obolibrary.org/obo/UPHENO_0025532
+http://purl.obolibrary.org/obo/UBERON_0001645	http://purl.obolibrary.org/obo/UBERON_0001785	http://purl.obolibrary.org/obo/UPHENO_0025533
+http://purl.obolibrary.org/obo/UBERON_0001649	http://purl.obolibrary.org/obo/UBERON_0001785	http://purl.obolibrary.org/obo/UPHENO_0025534
+http://purl.obolibrary.org/obo/UBERON_0002422	http://purl.obolibrary.org/obo/UBERON_0004086	http://purl.obolibrary.org/obo/UPHENO_0025535
+http://purl.obolibrary.org/obo/CL_0000049	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0001776	http://purl.obolibrary.org/obo/UPHENO_0026555
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0001891	http://purl.obolibrary.org/obo/UPHENO_0026051
+http://purl.obolibrary.org/obo/CL_0000542	http://purl.obolibrary.org/obo/UBERON_0002405	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0001895	http://purl.obolibrary.org/obo/UPHENO_0026053
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0001645	http://purl.obolibrary.org/obo/UPHENO_0027048
+http://purl.obolibrary.org/obo/CL_0000218	http://purl.obolibrary.org/obo/UBERON_0000010	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002369	http://purl.obolibrary.org/obo/UBERON_0002113	http://purl.obolibrary.org/obo/UPHENO_0027052
+http://purl.obolibrary.org/obo/UBERON_0002037	http://purl.obolibrary.org/obo/UBERON_0001895	http://purl.obolibrary.org/obo/UPHENO_0025558
+http://purl.obolibrary.org/obo/CL_1000191	http://purl.obolibrary.org/obo/UBERON_0002227	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001300	http://purl.obolibrary.org/obo/UBERON_0000990	http://purl.obolibrary.org/obo/UPHENO_0026575
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0001756	http://purl.obolibrary.org/obo/UPHENO_0026579
+http://purl.obolibrary.org/obo/UBERON_0002393	http://purl.obolibrary.org/obo/UBERON_0001756	http://purl.obolibrary.org/obo/UPHENO_0026581
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/CL_0000589	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001264	http://purl.obolibrary.org/obo/UBERON_0000468	http://purl.obolibrary.org/obo/UPHENO_0025566
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0003947	http://purl.obolibrary.org/obo/UPHENO_0026588
+http://purl.obolibrary.org/obo/UBERON_0001752	http://purl.obolibrary.org/obo/UBERON_0001091	http://purl.obolibrary.org/obo/UPHENO_0026070
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0001648	http://purl.obolibrary.org/obo/UPHENO_0027063
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0001769	http://purl.obolibrary.org/obo/UPHENO_0026589
+http://purl.obolibrary.org/obo/UBERON_0001819	http://purl.obolibrary.org/obo/UBERON_0010409	http://purl.obolibrary.org/obo/UPHENO_0025568
+http://purl.obolibrary.org/obo/UBERON_0001643	http://purl.obolibrary.org/obo/UBERON_0001785	http://purl.obolibrary.org/obo/UPHENO_0025573
+http://purl.obolibrary.org/obo/UBERON_0001644	http://purl.obolibrary.org/obo/UBERON_0001785	http://purl.obolibrary.org/obo/UPHENO_0025574
diff --git a/src/curation/upheno-fillers/mp/abnormalAbsenceOfBehavior.tsv b/src/curation/upheno-fillers/mp/abnormalAbsenceOfBehavior.tsv
new file mode 100644
index 00000000..0d51f54c
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormalAbsenceOfBehavior.tsv
@@ -0,0 +1,11 @@
+behavior_process	defined_class
+http://purl.obolibrary.org/obo/NBO_0000334	http://purl.obolibrary.org/obo/UPHENO_0080660
+http://purl.obolibrary.org/obo/NBO_0000576	http://purl.obolibrary.org/obo/UPHENO_0063687
+http://purl.obolibrary.org/obo/NBO_0000313	http://purl.obolibrary.org/obo/UPHENO_0063688
+http://purl.obolibrary.org/obo/NBO_0000401	http://purl.obolibrary.org/obo/UPHENO_0063689
+http://purl.obolibrary.org/obo/NBO_0000416	http://purl.obolibrary.org/obo/UPHENO_0063690
+http://purl.obolibrary.org/obo/NBO_0000449	http://purl.obolibrary.org/obo/UPHENO_0063691
+http://purl.obolibrary.org/obo/NBO_0000391	http://purl.obolibrary.org/obo/UPHENO_0063692
+http://purl.obolibrary.org/obo/NBO_0000418	http://purl.obolibrary.org/obo/UPHENO_0063693
+http://purl.obolibrary.org/obo/NBO_0000154	http://purl.obolibrary.org/obo/UPHENO_0063694
+http://purl.obolibrary.org/obo/NBO_0000332	http://purl.obolibrary.org/obo/UPHENO_0063695
diff --git a/src/curation/upheno-fillers/mp/abnormalAbsenceOfBiologicalProcess.tsv b/src/curation/upheno-fillers/mp/abnormalAbsenceOfBiologicalProcess.tsv
new file mode 100644
index 00000000..805cd9c5
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormalAbsenceOfBiologicalProcess.tsv
@@ -0,0 +1,43 @@
+biological_process	defined_class
+http://purl.obolibrary.org/obo/GO_0001880	http://purl.obolibrary.org/obo/UPHENO_0078454
+http://purl.obolibrary.org/obo/GO_0001542	http://purl.obolibrary.org/obo/UPHENO_0084435
+http://purl.obolibrary.org/obo/GO_0007369	http://purl.obolibrary.org/obo/UPHENO_0078455
+http://purl.obolibrary.org/obo/NBO_0000401	http://purl.obolibrary.org/obo/UPHENO_0080947
+http://purl.obolibrary.org/obo/GO_0007601	http://purl.obolibrary.org/obo/UPHENO_0078456
+http://purl.obolibrary.org/obo/GO_0044691	http://purl.obolibrary.org/obo/UPHENO_0078457
+http://purl.obolibrary.org/obo/GO_0007605	http://purl.obolibrary.org/obo/UPHENO_0078458
+http://purl.obolibrary.org/obo/NBO_0000449	http://purl.obolibrary.org/obo/UPHENO_0080948
+http://purl.obolibrary.org/obo/GO_0007566	http://purl.obolibrary.org/obo/UPHENO_0078460
+http://purl.obolibrary.org/obo/GO_0007585	http://purl.obolibrary.org/obo/UPHENO_0078461
+http://purl.obolibrary.org/obo/GO_0048539	http://purl.obolibrary.org/obo/UPHENO_0078463
+http://purl.obolibrary.org/obo/NBO_0000391	http://purl.obolibrary.org/obo/UPHENO_0080949
+http://purl.obolibrary.org/obo/GO_0060004	http://purl.obolibrary.org/obo/UPHENO_0034031
+http://purl.obolibrary.org/obo/GO_0001569	http://purl.obolibrary.org/obo/UPHENO_0078464
+http://purl.obolibrary.org/obo/GO_0099129	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0001649	http://purl.obolibrary.org/obo/UPHENO_0078465
+http://purl.obolibrary.org/obo/GO_0001825	http://purl.obolibrary.org/obo/UPHENO_0078466
+http://purl.obolibrary.org/obo/NBO_0000332	http://purl.obolibrary.org/obo/UPHENO_0080950
+http://purl.obolibrary.org/obo/GO_0001947	http://purl.obolibrary.org/obo/UPHENO_0078467
+http://purl.obolibrary.org/obo/NBO_0000154	http://purl.obolibrary.org/obo/UPHENO_0080951
+http://purl.obolibrary.org/obo/GO_0060209	http://purl.obolibrary.org/obo/UPHENO_0078468
+http://purl.obolibrary.org/obo/GO_0010070	http://purl.obolibrary.org/obo/UPHENO_0078469
+http://purl.obolibrary.org/obo/GO_0001550	http://purl.obolibrary.org/obo/UPHENO_0078470
+http://purl.obolibrary.org/obo/NBO_0000334	http://purl.obolibrary.org/obo/UPHENO_0080952
+http://purl.obolibrary.org/obo/NBO_0000576	http://purl.obolibrary.org/obo/UPHENO_0080953
+http://purl.obolibrary.org/obo/GO_0048144	http://purl.obolibrary.org/obo/UPHENO_0078471
+http://purl.obolibrary.org/obo/NBO_0000418	http://purl.obolibrary.org/obo/UPHENO_0080954
+http://purl.obolibrary.org/obo/GO_0030317	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/NBO_0000416	http://purl.obolibrary.org/obo/UPHENO_0080955
+http://purl.obolibrary.org/obo/GO_0045453	http://purl.obolibrary.org/obo/UPHENO_0078472
+http://purl.obolibrary.org/obo/GO_0007595	http://purl.obolibrary.org/obo/UPHENO_0078473
+http://purl.obolibrary.org/obo/GO_0060073	http://purl.obolibrary.org/obo/UPHENO_0078474
+http://purl.obolibrary.org/obo/GO_0060292	http://purl.obolibrary.org/obo/UPHENO_0078475
+http://purl.obolibrary.org/obo/GO_0060710	http://purl.obolibrary.org/obo/UPHENO_0078476
+http://purl.obolibrary.org/obo/GO_0090009	http://purl.obolibrary.org/obo/UPHENO_0078477
+http://purl.obolibrary.org/obo/GO_0060156	http://purl.obolibrary.org/obo/UPHENO_0078478
+http://purl.obolibrary.org/obo/GO_0042703	http://purl.obolibrary.org/obo/UPHENO_0078479
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UPHENO_0034024
+http://purl.obolibrary.org/obo/GO_0042628	http://purl.obolibrary.org/obo/UPHENO_0078480
+http://purl.obolibrary.org/obo/GO_0001834	http://purl.obolibrary.org/obo/UPHENO_0078481
+http://purl.obolibrary.org/obo/GO_0001833	http://purl.obolibrary.org/obo/UPHENO_0078482
+http://purl.obolibrary.org/obo/GO_0030099	http://purl.obolibrary.org/obo/UPHENO_0078485
diff --git a/src/curation/upheno-fillers/mp/abnormalAbsenceOfBiologicalProcessInLocation.tsv b/src/curation/upheno-fillers/mp/abnormalAbsenceOfBiologicalProcessInLocation.tsv
new file mode 100644
index 00000000..865971af
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormalAbsenceOfBiologicalProcessInLocation.tsv
@@ -0,0 +1,24 @@
+biological_process	location	defined_class
+http://purl.obolibrary.org/obo/GO_0048242	http://purl.obolibrary.org/obo/UBERON_0002369	http://purl.obolibrary.org/obo/UPHENO_0071040
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0000019	http://purl.obolibrary.org/obo/UPHENO_0071105
+http://purl.obolibrary.org/obo/GO_0043473	http://purl.obolibrary.org/obo/UBERON_0010162	http://purl.obolibrary.org/obo/UPHENO_0071021
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0001007	http://purl.obolibrary.org/obo/UPHENO_0071068
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0006012	http://purl.obolibrary.org/obo/UPHENO_0071069
+http://purl.obolibrary.org/obo/GO_0046903	http://purl.obolibrary.org/obo/UBERON_0001007	http://purl.obolibrary.org/obo/UPHENO_0071071
+http://purl.obolibrary.org/obo/GO_0060047	http://purl.obolibrary.org/obo/UBERON_0000948	http://purl.obolibrary.org/obo/UPHENO_0071023
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0002097	http://purl.obolibrary.org/obo/UPHENO_0071024
+http://purl.obolibrary.org/obo/GO_0006582	http://purl.obolibrary.org/obo/UBERON_0000019	http://purl.obolibrary.org/obo/UPHENO_0071027
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0001820	http://purl.obolibrary.org/obo/UPHENO_0071047
+http://purl.obolibrary.org/obo/GO_0009058	http://purl.obolibrary.org/obo/GO_0005604	http://purl.obolibrary.org/obo/UPHENO_0084651
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0009024	http://purl.obolibrary.org/obo/UPHENO_0071049
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0001884	http://purl.obolibrary.org/obo/UPHENO_0071076
+http://purl.obolibrary.org/obo/GO_0012501	http://purl.obolibrary.org/obo/UBERON_0009024	http://purl.obolibrary.org/obo/UPHENO_0071110
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0000948	http://purl.obolibrary.org/obo/UPHENO_0071079
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/GO_0005604	http://purl.obolibrary.org/obo/UPHENO_0084652
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0010162	http://purl.obolibrary.org/obo/UPHENO_0071057
+http://purl.obolibrary.org/obo/GO_0006915	http://purl.obolibrary.org/obo/UBERON_0006012	http://purl.obolibrary.org/obo/UPHENO_0071031
+http://purl.obolibrary.org/obo/GO_0043473	http://purl.obolibrary.org/obo/UBERON_0002097	http://purl.obolibrary.org/obo/UPHENO_0071117
+http://purl.obolibrary.org/obo/GO_0007413	http://purl.obolibrary.org/obo/UBERON_0001884	http://purl.obolibrary.org/obo/UPHENO_0071034
+http://purl.obolibrary.org/obo/GO_0043473	http://purl.obolibrary.org/obo/UBERON_0000019	http://purl.obolibrary.org/obo/UPHENO_0071090
+http://purl.obolibrary.org/obo/GO_0046903	http://purl.obolibrary.org/obo/UBERON_0001820	http://purl.obolibrary.org/obo/UPHENO_0071035
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0002369	http://purl.obolibrary.org/obo/UPHENO_0071097
diff --git a/src/curation/upheno-fillers/mp/abnormalAbsenceOfChemicalEntity.tsv b/src/curation/upheno-fillers/mp/abnormalAbsenceOfChemicalEntity.tsv
new file mode 100644
index 00000000..ebf916de
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormalAbsenceOfChemicalEntity.tsv
@@ -0,0 +1,4 @@
+chemical_entity	defined_class
+http://purl.obolibrary.org/obo/PR_000011107	http://purl.obolibrary.org/obo/UPHENO_0048686
+http://purl.obolibrary.org/obo/CHEBI_24431	http://purl.obolibrary.org/obo/UPHENO_0048687
+http://purl.obolibrary.org/obo/CHEBI_25805	http://purl.obolibrary.org/obo/UPHENO_0048688
diff --git a/src/curation/upheno-fillers/mp/abnormalAbsenceOfChemicalEntityInLocation.tsv b/src/curation/upheno-fillers/mp/abnormalAbsenceOfChemicalEntityInLocation.tsv
new file mode 100644
index 00000000..c9c5561d
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormalAbsenceOfChemicalEntityInLocation.tsv
@@ -0,0 +1,4 @@
+chemical_entity	location	defined_class
+http://purl.obolibrary.org/obo/CHEBI_33568	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0049567
+http://purl.obolibrary.org/obo/CHEBI_33569	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0049568
+http://purl.obolibrary.org/obo/CHEBI_24431	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0049570
diff --git a/src/curation/upheno-fillers/mp/abnormalAnatomicalEntity-modified.tsv b/src/curation/upheno-fillers/mp/abnormalAnatomicalEntity-modified.tsv
new file mode 100644
index 00000000..8ea454d9
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormalAnatomicalEntity-modified.tsv
@@ -0,0 +1,87 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0002360	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000120	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002282	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0010412	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000125	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0010416	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0010417	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001037	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002007	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001798	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000081	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002127	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002006	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001077	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0003697	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001992	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0005356	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001310	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002519	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000806	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001946	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002518	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001305	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001945	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002956	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002195	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0004451	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002076	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000650	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000452	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0005184	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0004096	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000653	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001862	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002279	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0000412	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002077	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0005620	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002310	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0014451	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0000325	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0012352	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0010513	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0010514	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0010511	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0010753	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0010512	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000300	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002467	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0000365	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002226	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001852	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002468	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002303	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001896	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0001917	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0005810	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001726	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001849	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001843	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002979	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001725	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001845	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001080	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0002092	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001322	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0006615	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001842	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002974	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001841	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002215	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0006216	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0000396	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0005367	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0004871	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0004872	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001839	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002448	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0011161	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0003614	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0006606	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0000795	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0010395	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000835	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0010510	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/mp/abnormalAnatomicalEntityNotParts.tsv b/src/curation/upheno-fillers/mp/abnormalAnatomicalEntityNotParts.tsv
new file mode 100644
index 00000000..3fb570c8
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormalAnatomicalEntityNotParts.tsv
@@ -0,0 +1,87 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0002360	http://purl.obolibrary.org/obo/UPHENO_0075672
+http://purl.obolibrary.org/obo/CL_0000120	http://purl.obolibrary.org/obo/UPHENO_0087306
+http://purl.obolibrary.org/obo/UBERON_0002282	http://purl.obolibrary.org/obo/UPHENO_0075673
+http://purl.obolibrary.org/obo/UBERON_0010412	http://purl.obolibrary.org/obo/UPHENO_0075674
+http://purl.obolibrary.org/obo/CL_0000125	http://purl.obolibrary.org/obo/UPHENO_0087307
+http://purl.obolibrary.org/obo/UBERON_0010416	http://purl.obolibrary.org/obo/UPHENO_0075675
+http://purl.obolibrary.org/obo/UBERON_0010417	http://purl.obolibrary.org/obo/UPHENO_0075676
+http://purl.obolibrary.org/obo/UBERON_0001037	http://purl.obolibrary.org/obo/UPHENO_0075677
+http://purl.obolibrary.org/obo/UBERON_0002007	http://purl.obolibrary.org/obo/UPHENO_0075678
+http://purl.obolibrary.org/obo/UBERON_0001798	http://purl.obolibrary.org/obo/UPHENO_0075679
+http://purl.obolibrary.org/obo/CL_0000081	http://purl.obolibrary.org/obo/UPHENO_0087308
+http://purl.obolibrary.org/obo/UBERON_0002127	http://purl.obolibrary.org/obo/UPHENO_0075680
+http://purl.obolibrary.org/obo/UBERON_0002006	http://purl.obolibrary.org/obo/UPHENO_0075681
+http://purl.obolibrary.org/obo/UBERON_0001077	http://purl.obolibrary.org/obo/UPHENO_0075683
+http://purl.obolibrary.org/obo/UBERON_0003697	http://purl.obolibrary.org/obo/UPHENO_0075684
+http://purl.obolibrary.org/obo/UBERON_0001992	http://purl.obolibrary.org/obo/UPHENO_0075687
+http://purl.obolibrary.org/obo/UBERON_0005356	http://purl.obolibrary.org/obo/UPHENO_0075688
+http://purl.obolibrary.org/obo/UBERON_0001310	http://purl.obolibrary.org/obo/UPHENO_0075689
+http://purl.obolibrary.org/obo/UBERON_0002519	http://purl.obolibrary.org/obo/UPHENO_0075690
+http://purl.obolibrary.org/obo/CL_0000806	http://purl.obolibrary.org/obo/UPHENO_0087309
+http://purl.obolibrary.org/obo/UBERON_0001946	http://purl.obolibrary.org/obo/UPHENO_0075691
+http://purl.obolibrary.org/obo/UBERON_0002518	http://purl.obolibrary.org/obo/UPHENO_0075692
+http://purl.obolibrary.org/obo/UBERON_0001305	http://purl.obolibrary.org/obo/UPHENO_0075693
+http://purl.obolibrary.org/obo/UBERON_0001945	http://purl.obolibrary.org/obo/UPHENO_0075694
+http://purl.obolibrary.org/obo/UBERON_0002956	http://purl.obolibrary.org/obo/UPHENO_0075695
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0075696
+http://purl.obolibrary.org/obo/UBERON_0002195	http://purl.obolibrary.org/obo/UPHENO_0075697
+http://purl.obolibrary.org/obo/UBERON_0004451	http://purl.obolibrary.org/obo/UPHENO_0075698
+http://purl.obolibrary.org/obo/UBERON_0002076	http://purl.obolibrary.org/obo/UPHENO_0075699
+http://purl.obolibrary.org/obo/CL_0000650	http://purl.obolibrary.org/obo/UPHENO_0087310
+http://purl.obolibrary.org/obo/CL_0000452	http://purl.obolibrary.org/obo/UPHENO_0087311
+http://purl.obolibrary.org/obo/UBERON_0005184	http://purl.obolibrary.org/obo/UPHENO_0075700
+http://purl.obolibrary.org/obo/UBERON_0004096	http://purl.obolibrary.org/obo/UPHENO_0075701
+http://purl.obolibrary.org/obo/CL_0000653	http://purl.obolibrary.org/obo/UPHENO_0087312
+http://purl.obolibrary.org/obo/UBERON_0001862	http://purl.obolibrary.org/obo/UPHENO_0075702
+http://purl.obolibrary.org/obo/UBERON_0002279	http://purl.obolibrary.org/obo/UPHENO_0075703
+http://purl.obolibrary.org/obo/UBERON_0000412	http://purl.obolibrary.org/obo/UPHENO_0075704
+http://purl.obolibrary.org/obo/UBERON_0002077	http://purl.obolibrary.org/obo/UPHENO_0075705
+http://purl.obolibrary.org/obo/UBERON_0005620	http://purl.obolibrary.org/obo/UPHENO_0075707
+http://purl.obolibrary.org/obo/UBERON_0002310	http://purl.obolibrary.org/obo/UPHENO_0075708
+http://purl.obolibrary.org/obo/UBERON_0014451	http://purl.obolibrary.org/obo/UPHENO_0075709
+http://purl.obolibrary.org/obo/UBERON_0000325	http://purl.obolibrary.org/obo/UPHENO_0075710
+http://purl.obolibrary.org/obo/UBERON_0012352	http://purl.obolibrary.org/obo/UPHENO_0075713
+http://purl.obolibrary.org/obo/UBERON_0010513	http://purl.obolibrary.org/obo/UPHENO_0075714
+http://purl.obolibrary.org/obo/UBERON_0010514	http://purl.obolibrary.org/obo/UPHENO_0075715
+http://purl.obolibrary.org/obo/UBERON_0010511	http://purl.obolibrary.org/obo/UPHENO_0075716
+http://purl.obolibrary.org/obo/UBERON_0010753	http://purl.obolibrary.org/obo/UPHENO_0075717
+http://purl.obolibrary.org/obo/UBERON_0010512	http://purl.obolibrary.org/obo/UPHENO_0075718
+http://purl.obolibrary.org/obo/CL_0000300	http://purl.obolibrary.org/obo/UPHENO_0087313
+http://purl.obolibrary.org/obo/UBERON_0002467	http://purl.obolibrary.org/obo/UPHENO_0075719
+http://purl.obolibrary.org/obo/UBERON_0000365	http://purl.obolibrary.org/obo/UPHENO_0075720
+http://purl.obolibrary.org/obo/UBERON_0002226	http://purl.obolibrary.org/obo/UPHENO_0075721
+http://purl.obolibrary.org/obo/UBERON_0001852	http://purl.obolibrary.org/obo/UPHENO_0075722
+http://purl.obolibrary.org/obo/UBERON_0002468	http://purl.obolibrary.org/obo/UPHENO_0075723
+http://purl.obolibrary.org/obo/UBERON_0002303	http://purl.obolibrary.org/obo/UPHENO_0075724
+http://purl.obolibrary.org/obo/UBERON_0001896	http://purl.obolibrary.org/obo/UPHENO_0075725
+http://purl.obolibrary.org/obo/GO_0001917	http://purl.obolibrary.org/obo/UPHENO_0087314
+http://purl.obolibrary.org/obo/UBERON_0005810	http://purl.obolibrary.org/obo/UPHENO_0075726
+http://purl.obolibrary.org/obo/UBERON_0001726	http://purl.obolibrary.org/obo/UPHENO_0075729
+http://purl.obolibrary.org/obo/UBERON_0001849	http://purl.obolibrary.org/obo/UPHENO_0075730
+http://purl.obolibrary.org/obo/UBERON_0001843	http://purl.obolibrary.org/obo/UPHENO_0075731
+http://purl.obolibrary.org/obo/UBERON_0002979	http://purl.obolibrary.org/obo/UPHENO_0075732
+http://purl.obolibrary.org/obo/UBERON_0001725	http://purl.obolibrary.org/obo/UPHENO_0075733
+http://purl.obolibrary.org/obo/UBERON_0001845	http://purl.obolibrary.org/obo/UPHENO_0075734
+http://purl.obolibrary.org/obo/UBERON_0001080	http://purl.obolibrary.org/obo/UPHENO_0075735
+http://purl.obolibrary.org/obo/CL_0002092	http://purl.obolibrary.org/obo/UPHENO_0087315
+http://purl.obolibrary.org/obo/UBERON_0001322	http://purl.obolibrary.org/obo/UPHENO_0075736
+http://purl.obolibrary.org/obo/UBERON_0006615	http://purl.obolibrary.org/obo/UPHENO_0075737
+http://purl.obolibrary.org/obo/UBERON_0001842	http://purl.obolibrary.org/obo/UPHENO_0075738
+http://purl.obolibrary.org/obo/UBERON_0002974	http://purl.obolibrary.org/obo/UPHENO_0075739
+http://purl.obolibrary.org/obo/UBERON_0001841	http://purl.obolibrary.org/obo/UPHENO_0075740
+http://purl.obolibrary.org/obo/UBERON_0002215	http://purl.obolibrary.org/obo/UPHENO_0075741
+http://purl.obolibrary.org/obo/UBERON_0006216	http://purl.obolibrary.org/obo/UPHENO_0075742
+http://purl.obolibrary.org/obo/UBERON_0000396	http://purl.obolibrary.org/obo/UPHENO_0075743
+http://purl.obolibrary.org/obo/UBERON_0005367	http://purl.obolibrary.org/obo/UPHENO_0075744
+http://purl.obolibrary.org/obo/UBERON_0004871	http://purl.obolibrary.org/obo/UPHENO_0075745
+http://purl.obolibrary.org/obo/UBERON_0004872	http://purl.obolibrary.org/obo/UPHENO_0075746
+http://purl.obolibrary.org/obo/UBERON_0001839	http://purl.obolibrary.org/obo/UPHENO_0075747
+http://purl.obolibrary.org/obo/UBERON_0002448	http://purl.obolibrary.org/obo/UPHENO_0075748
+http://purl.obolibrary.org/obo/UBERON_0011161	http://purl.obolibrary.org/obo/UPHENO_0075749
+http://purl.obolibrary.org/obo/UBERON_0003614	http://purl.obolibrary.org/obo/UPHENO_0075750
+http://purl.obolibrary.org/obo/UBERON_0006606	http://purl.obolibrary.org/obo/UPHENO_0075751
+http://purl.obolibrary.org/obo/GO_0000795	http://purl.obolibrary.org/obo/UPHENO_0087316
+http://purl.obolibrary.org/obo/UBERON_0010395	http://purl.obolibrary.org/obo/UPHENO_0075752
+http://purl.obolibrary.org/obo/CL_0000835	http://purl.obolibrary.org/obo/UPHENO_0087317
+http://purl.obolibrary.org/obo/UBERON_0010510	http://purl.obolibrary.org/obo/UPHENO_0075753
diff --git a/src/curation/upheno-fillers/mp/abnormalBehavior.tsv b/src/curation/upheno-fillers/mp/abnormalBehavior.tsv
new file mode 100644
index 00000000..1bfe57fd
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormalBehavior.tsv
@@ -0,0 +1,5 @@
+behavior_process	defined_class
+http://purl.obolibrary.org/obo/NBO_0000313	http://purl.obolibrary.org/obo/UPHENO_0079826
+http://purl.obolibrary.org/obo/NBO_0001987	http://purl.obolibrary.org/obo/UPHENO_0079827
+http://purl.obolibrary.org/obo/NBO_0000221	http://purl.obolibrary.org/obo/UPHENO_0081793
+http://purl.obolibrary.org/obo/NBO_0000211	http://purl.obolibrary.org/obo/UPHENO_0081794
diff --git a/src/curation/upheno-fillers/mp/abnormalBiologicalProcess.tsv b/src/curation/upheno-fillers/mp/abnormalBiologicalProcess.tsv
new file mode 100644
index 00000000..8d0fb0d3
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormalBiologicalProcess.tsv
@@ -0,0 +1,14 @@
+biological_process	defined_class
+http://purl.obolibrary.org/obo/NBO_0001987	http://purl.obolibrary.org/obo/UPHENO_0080578
+http://purl.obolibrary.org/obo/GO_0097421	http://purl.obolibrary.org/obo/UPHENO_0051010
+http://purl.obolibrary.org/obo/GO_0001666	http://purl.obolibrary.org/obo/UPHENO_0049879
+http://purl.obolibrary.org/obo/GO_0007143	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0044321	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0007056	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0043403	http://purl.obolibrary.org/obo/UPHENO_0083067
+http://purl.obolibrary.org/obo/GO_0040038	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UPHENO_0049587
+http://purl.obolibrary.org/obo/GO_0061026	http://purl.obolibrary.org/obo/UPHENO_0051022
+http://purl.obolibrary.org/obo/GO_0099129	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/NBO_0000211	http://purl.obolibrary.org/obo/UPHENO_0080579
+http://purl.obolibrary.org/obo/NBO_0000221	http://purl.obolibrary.org/obo/UPHENO_0080580
diff --git a/src/curation/upheno-fillers/mp/abnormalBiologicalProcessInLocation.tsv b/src/curation/upheno-fillers/mp/abnormalBiologicalProcessInLocation.tsv
new file mode 100644
index 00000000..f6089ae9
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormalBiologicalProcessInLocation.tsv
@@ -0,0 +1,22 @@
+biological_process	location	defined_class
+http://purl.obolibrary.org/obo/GO_0042246	http://purl.obolibrary.org/obo/UBERON_0000160	http://purl.obolibrary.org/obo/UPHENO_0083950
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0012071	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0000975	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0001621	http://purl.obolibrary.org/obo/UPHENO_0081974
+http://purl.obolibrary.org/obo/GO_0042246	http://purl.obolibrary.org/obo/UBERON_0001264	http://purl.obolibrary.org/obo/UPHENO_0084656
+http://purl.obolibrary.org/obo/GO_0042246	http://purl.obolibrary.org/obo/UBERON_0000010	http://purl.obolibrary.org/obo/UPHENO_0083956
+http://purl.obolibrary.org/obo/GO_0008015	http://purl.obolibrary.org/obo/UBERON_0003512	http://purl.obolibrary.org/obo/UPHENO_0081977
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0001264	http://purl.obolibrary.org/obo/UPHENO_0084657
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0000010	http://purl.obolibrary.org/obo/UPHENO_0083958
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0000160	http://purl.obolibrary.org/obo/UPHENO_0078402
+http://purl.obolibrary.org/obo/GO_0032941	http://purl.obolibrary.org/obo/UBERON_0000160	http://purl.obolibrary.org/obo/UPHENO_0078403
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0001017	http://purl.obolibrary.org/obo/UPHENO_0083951
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0001016	http://purl.obolibrary.org/obo/UPHENO_0083952
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0003512	http://purl.obolibrary.org/obo/UPHENO_0081975
+http://purl.obolibrary.org/obo/GO_0042246	http://purl.obolibrary.org/obo/UBERON_0001016	http://purl.obolibrary.org/obo/UPHENO_0083953
+http://purl.obolibrary.org/obo/GO_0042246	http://purl.obolibrary.org/obo/UBERON_0001017	http://purl.obolibrary.org/obo/UPHENO_0083954
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0001630	http://purl.obolibrary.org/obo/UPHENO_0083955
+http://purl.obolibrary.org/obo/GO_0001503	http://purl.obolibrary.org/obo/UBERON_0012071	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0008015	http://purl.obolibrary.org/obo/UBERON_0001621	http://purl.obolibrary.org/obo/UPHENO_0081976
+http://purl.obolibrary.org/obo/GO_0001958	http://purl.obolibrary.org/obo/UBERON_0000975	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0042246	http://purl.obolibrary.org/obo/UBERON_0001630	http://purl.obolibrary.org/obo/UPHENO_0083957
diff --git a/src/curation/upheno-fillers/mp/abnormalCellularComponent-modified.tsv b/src/curation/upheno-fillers/mp/abnormalCellularComponent-modified.tsv
new file mode 100644
index 00000000..74457cb4
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormalCellularComponent-modified.tsv
@@ -0,0 +1,4 @@
+cellular_component	defined_class
+http://purl.obolibrary.org/obo/GO_0005575	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0001917	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0000795	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/mp/abnormalCoilingOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/mp/abnormalCoilingOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..96df46bf
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormalCoilingOfAnatomicalEntity.tsv
@@ -0,0 +1,4 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0078441
+http://purl.obolibrary.org/obo/GO_0036126	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001153	http://purl.obolibrary.org/obo/UPHENO_0078442
diff --git a/src/curation/upheno-fillers/mp/abnormalColorOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/mp/abnormalColorOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..4f98ce4f
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormalColorOfAnatomicalEntity.tsv
@@ -0,0 +1,10 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0080210
+http://purl.obolibrary.org/obo/UBERON_0001705	http://purl.obolibrary.org/obo/UPHENO_0080211
+http://purl.obolibrary.org/obo/UBERON_0003450	http://purl.obolibrary.org/obo/UPHENO_0080212
+http://purl.obolibrary.org/obo/UBERON_0003451	http://purl.obolibrary.org/obo/UPHENO_0080213
+http://purl.obolibrary.org/obo/UBERON_0001828	http://purl.obolibrary.org/obo/UPHENO_0080214
+http://purl.obolibrary.org/obo/UBERON_0001091	http://purl.obolibrary.org/obo/UPHENO_0080215
+http://purl.obolibrary.org/obo/UBERON_0001088	http://purl.obolibrary.org/obo/UPHENO_0080216
+http://purl.obolibrary.org/obo/UBERON_0001098	http://purl.obolibrary.org/obo/UPHENO_0080217
+http://purl.obolibrary.org/obo/UBERON_0001970	http://purl.obolibrary.org/obo/UPHENO_0080218
diff --git a/src/curation/upheno-fillers/mp/abnormalColorOfAnatomicalEntityByColor.tsv b/src/curation/upheno-fillers/mp/abnormalColorOfAnatomicalEntityByColor.tsv
new file mode 100644
index 00000000..59232526
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormalColorOfAnatomicalEntityByColor.tsv
@@ -0,0 +1,17 @@
+color	entity	defined_class
+http://purl.obolibrary.org/obo/PATO_0000319	http://purl.obolibrary.org/obo/UBERON_0000014	http://purl.obolibrary.org/obo/UPHENO_0083437
+http://purl.obolibrary.org/obo/PATO_0000319	http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0083438
+http://purl.obolibrary.org/obo/PATO_0000014	http://purl.obolibrary.org/obo/UBERON_0001037	http://purl.obolibrary.org/obo/UPHENO_0083439
+http://purl.obolibrary.org/obo/PATO_0000014	http://purl.obolibrary.org/obo/UBERON_0000014	http://purl.obolibrary.org/obo/UPHENO_0083440
+http://purl.obolibrary.org/obo/PATO_0000322	http://purl.obolibrary.org/obo/UBERON_0000014	http://purl.obolibrary.org/obo/UPHENO_0083441
+http://purl.obolibrary.org/obo/PATO_0000324	http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0083442
+http://purl.obolibrary.org/obo/PATO_0000322	http://purl.obolibrary.org/obo/UBERON_0001091	http://purl.obolibrary.org/obo/UPHENO_0083443
+http://purl.obolibrary.org/obo/PATO_0000014	http://purl.obolibrary.org/obo/UBERON_0001091	http://purl.obolibrary.org/obo/UPHENO_0083444
+http://purl.obolibrary.org/obo/PATO_0000324	http://purl.obolibrary.org/obo/UBERON_0001037	http://purl.obolibrary.org/obo/UPHENO_0083445
+http://purl.obolibrary.org/obo/PATO_0000322	http://purl.obolibrary.org/obo/UBERON_0001088	http://purl.obolibrary.org/obo/UPHENO_0083446
+http://purl.obolibrary.org/obo/PATO_0000014	http://purl.obolibrary.org/obo/UBERON_0001088	http://purl.obolibrary.org/obo/UPHENO_0083447
+http://purl.obolibrary.org/obo/PATO_0000014	http://purl.obolibrary.org/obo/UBERON_0001771	http://purl.obolibrary.org/obo/UPHENO_0083448
+http://purl.obolibrary.org/obo/PATO_0000323	http://purl.obolibrary.org/obo/UBERON_0001771	http://purl.obolibrary.org/obo/UPHENO_0083449
+http://purl.obolibrary.org/obo/PATO_0000014	http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0083450
+http://purl.obolibrary.org/obo/PATO_0000322	http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0083451
+http://purl.obolibrary.org/obo/PATO_0000323	http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0083452
diff --git a/src/curation/upheno-fillers/mp/abnormalConstrictionOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/mp/abnormalConstrictionOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..d0ee2f57
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormalConstrictionOfAnatomicalEntity.tsv
@@ -0,0 +1,50 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0012317	http://purl.obolibrary.org/obo/UPHENO_0081821
+http://purl.obolibrary.org/obo/UBERON_0002083	http://purl.obolibrary.org/obo/UPHENO_0081824
+http://purl.obolibrary.org/obo/UBERON_0005956	http://purl.obolibrary.org/obo/UPHENO_0081825
+http://purl.obolibrary.org/obo/UBERON_0005953	http://purl.obolibrary.org/obo/UPHENO_0081826
+http://purl.obolibrary.org/obo/UBERON_0001352	http://purl.obolibrary.org/obo/UPHENO_0083910
+http://purl.obolibrary.org/obo/UBERON_0002289	http://purl.obolibrary.org/obo/UPHENO_0081829
+http://purl.obolibrary.org/obo/UBERON_0001310	http://purl.obolibrary.org/obo/UPHENO_0081831
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0081834
+http://purl.obolibrary.org/obo/UBERON_0004771	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001184	http://purl.obolibrary.org/obo/UPHENO_0081837
+http://purl.obolibrary.org/obo/UBERON_0001620	http://purl.obolibrary.org/obo/UPHENO_0081840
+http://purl.obolibrary.org/obo/UBERON_0000057	http://purl.obolibrary.org/obo/UPHENO_0081841
+http://purl.obolibrary.org/obo/UBERON_0003687	http://purl.obolibrary.org/obo/UPHENO_0081842
+http://purl.obolibrary.org/obo/UBERON_0005745	http://purl.obolibrary.org/obo/UPHENO_0081843
+http://purl.obolibrary.org/obo/UBERON_0003126	http://purl.obolibrary.org/obo/UPHENO_0081844
+http://purl.obolibrary.org/obo/UBERON_0001621	http://purl.obolibrary.org/obo/UPHENO_0081846
+http://purl.obolibrary.org/obo/UBERON_0005623	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0004015	http://purl.obolibrary.org/obo/UPHENO_0081847
+http://purl.obolibrary.org/obo/UBERON_0001981	http://purl.obolibrary.org/obo/UPHENO_0081851
+http://purl.obolibrary.org/obo/UBERON_0000056	http://purl.obolibrary.org/obo/UPHENO_0081854
+http://purl.obolibrary.org/obo/UBERON_0001737	http://purl.obolibrary.org/obo/UPHENO_0081856
+http://purl.obolibrary.org/obo/UBERON_0010172	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002505	http://purl.obolibrary.org/obo/UPHENO_0081861
+http://purl.obolibrary.org/obo/UBERON_0036068	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0004363	http://purl.obolibrary.org/obo/UPHENO_0081820
+http://purl.obolibrary.org/obo/UBERON_0000160	http://purl.obolibrary.org/obo/UPHENO_0081822
+http://purl.obolibrary.org/obo/UBERON_0004086	http://purl.obolibrary.org/obo/UPHENO_0081823
+http://purl.obolibrary.org/obo/UBERON_0002066	http://purl.obolibrary.org/obo/UPHENO_0081827
+http://purl.obolibrary.org/obo/UBERON_0009972	http://purl.obolibrary.org/obo/UPHENO_0081828
+http://purl.obolibrary.org/obo/UBERON_0002146	http://purl.obolibrary.org/obo/UPHENO_0081830
+http://purl.obolibrary.org/obo/UBERON_0001771	http://purl.obolibrary.org/obo/UPHENO_0081832
+http://purl.obolibrary.org/obo/UBERON_0001042	http://purl.obolibrary.org/obo/UPHENO_0081836
+http://purl.obolibrary.org/obo/UBERON_0006692	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002137	http://purl.obolibrary.org/obo/UPHENO_0081838
+http://purl.obolibrary.org/obo/UBERON_0002016	http://purl.obolibrary.org/obo/UPHENO_0081839
+http://purl.obolibrary.org/obo/UBERON_0000159	http://purl.obolibrary.org/obo/UPHENO_0081845
+http://purl.obolibrary.org/obo/UBERON_0004711	http://purl.obolibrary.org/obo/UPHENO_0083911
+http://purl.obolibrary.org/obo/UBERON_0002133	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002012	http://purl.obolibrary.org/obo/UPHENO_0081848
+http://purl.obolibrary.org/obo/UBERON_0001043	http://purl.obolibrary.org/obo/UPHENO_0081849
+http://purl.obolibrary.org/obo/UBERON_0002135	http://purl.obolibrary.org/obo/UPHENO_0081850
+http://purl.obolibrary.org/obo/UBERON_0001166	http://purl.obolibrary.org/obo/UPHENO_0081852
+http://purl.obolibrary.org/obo/UBERON_0002134	http://purl.obolibrary.org/obo/UPHENO_0081853
+http://purl.obolibrary.org/obo/UBERON_0001639	http://purl.obolibrary.org/obo/UPHENO_0081855
+http://purl.obolibrary.org/obo/UBERON_0001638	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0000947	http://purl.obolibrary.org/obo/UPHENO_0081857
+http://purl.obolibrary.org/obo/UBERON_0001514	http://purl.obolibrary.org/obo/UPHENO_0081858
+http://purl.obolibrary.org/obo/UBERON_0001637	http://purl.obolibrary.org/obo/UPHENO_0081859
+http://purl.obolibrary.org/obo/UBERON_0002407	http://purl.obolibrary.org/obo/UPHENO_0081860
diff --git a/src/curation/upheno-fillers/mp/abnormalDegenerationOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/mp/abnormalDegenerationOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..da480eda
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormalDegenerationOfAnatomicalEntity.tsv
@@ -0,0 +1,84 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0002282	http://purl.obolibrary.org/obo/UPHENO_0073930
+http://purl.obolibrary.org/obo/CL_0000121	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000561	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000287	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002240	http://purl.obolibrary.org/obo/UPHENO_0073981
+http://purl.obolibrary.org/obo/UBERON_0007812	http://purl.obolibrary.org/obo/UPHENO_0073982
+http://purl.obolibrary.org/obo/UBERON_0002080	http://purl.obolibrary.org/obo/UPHENO_0073883
+http://purl.obolibrary.org/obo/CL_0000202	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0002666	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001675	http://purl.obolibrary.org/obo/UPHENO_0073885
+http://purl.obolibrary.org/obo/UBERON_0001630	http://purl.obolibrary.org/obo/UPHENO_0073932
+http://purl.obolibrary.org/obo/UBERON_0006725	http://purl.obolibrary.org/obo/UPHENO_0073986
+http://purl.obolibrary.org/obo/UBERON_0003655	http://purl.obolibrary.org/obo/UPHENO_0073843
+http://purl.obolibrary.org/obo/UBERON_0004544	http://purl.obolibrary.org/obo/UPHENO_0073989
+http://purl.obolibrary.org/obo/UBERON_0001791	http://purl.obolibrary.org/obo/UPHENO_0074108
+http://purl.obolibrary.org/obo/CL_0000609	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001789	http://purl.obolibrary.org/obo/UPHENO_0080535
+http://purl.obolibrary.org/obo/CL_0002669	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000601	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0002668	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000604	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000846	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0073937
+http://purl.obolibrary.org/obo/UBERON_0002073	http://purl.obolibrary.org/obo/UPHENO_0073896
+http://purl.obolibrary.org/obo/CL_0000650	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000573	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002190	http://purl.obolibrary.org/obo/UPHENO_0073900
+http://purl.obolibrary.org/obo/CL_0000059	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001301	http://purl.obolibrary.org/obo/UPHENO_0073901
+http://purl.obolibrary.org/obo/UBERON_0001066	http://purl.obolibrary.org/obo/UPHENO_0073944
+http://purl.obolibrary.org/obo/UBERON_0001264	http://purl.obolibrary.org/obo/UPHENO_0073993
+http://purl.obolibrary.org/obo/UBERON_0000053	http://purl.obolibrary.org/obo/UPHENO_0073994
+http://purl.obolibrary.org/obo/UBERON_0000010	http://purl.obolibrary.org/obo/UPHENO_0073852
+http://purl.obolibrary.org/obo/UBERON_0001981	http://purl.obolibrary.org/obo/UPHENO_0073947
+http://purl.obolibrary.org/obo/UBERON_0002113	http://purl.obolibrary.org/obo/UPHENO_0073996
+http://purl.obolibrary.org/obo/UBERON_0001343	http://purl.obolibrary.org/obo/UPHENO_0073853
+http://purl.obolibrary.org/obo/CL_0002670	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001817	http://purl.obolibrary.org/obo/UPHENO_0073999
+http://purl.obolibrary.org/obo/UBERON_0000325	http://purl.obolibrary.org/obo/UPHENO_0073906
+http://purl.obolibrary.org/obo/UBERON_0000964	http://purl.obolibrary.org/obo/UPHENO_0074000
+http://purl.obolibrary.org/obo/UBERON_0002107	http://purl.obolibrary.org/obo/UPHENO_0074001
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diff --git a/src/curation/upheno-fillers/mp/abnormalDegenerationOfCellularComponent.tsv b/src/curation/upheno-fillers/mp/abnormalDegenerationOfCellularComponent.tsv
new file mode 100644
index 00000000..f08267c5
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormalDegenerationOfCellularComponent.tsv
@@ -0,0 +1,5 @@
+cellular_component	defined_class
+http://purl.obolibrary.org/obo/GO_0005575	http://purl.obolibrary.org/obo/UPHENO_0079505
+http://purl.obolibrary.org/obo/GO_0001917	http://purl.obolibrary.org/obo/UPHENO_0079511
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diff --git a/src/curation/upheno-fillers/mp/abnormalFunctionalityOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/mp/abnormalFunctionalityOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..add92709
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormalFunctionalityOfAnatomicalEntity.tsv
@@ -0,0 +1,218 @@
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diff --git a/src/curation/upheno-fillers/mp/abnormalFunctionalityOfCellularComponent.tsv b/src/curation/upheno-fillers/mp/abnormalFunctionalityOfCellularComponent.tsv
new file mode 100644
index 00000000..2fa2d999
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormalFunctionalityOfCellularComponent.tsv
@@ -0,0 +1,13 @@
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diff --git a/src/curation/upheno-fillers/mp/abnormalFunctionalityOfPartOfAnatomicalEntity-modified.tsv b/src/curation/upheno-fillers/mp/abnormalFunctionalityOfPartOfAnatomicalEntity-modified.tsv
new file mode 100644
index 00000000..6812a72d
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormalFunctionalityOfPartOfAnatomicalEntity-modified.tsv
@@ -0,0 +1,218 @@
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diff --git a/src/curation/upheno-fillers/mp/abnormalFunctionalityOfPartOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/mp/abnormalFunctionalityOfPartOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..9daab4d5
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormalFunctionalityOfPartOfAnatomicalEntity.tsv
@@ -0,0 +1,3 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0082875
+http://purl.obolibrary.org/obo/UBERON_0001091	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/mp/abnormalHasExtraPartsOfTypeAnatomicalEntity.tsv b/src/curation/upheno-fillers/mp/abnormalHasExtraPartsOfTypeAnatomicalEntity.tsv
new file mode 100644
index 00000000..2ec8762b
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormalHasExtraPartsOfTypeAnatomicalEntity.tsv
@@ -0,0 +1,5 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0046217
+http://purl.obolibrary.org/obo/CL_0000891	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0005019	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000127	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/mp/abnormalHeightOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/mp/abnormalHeightOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..1116a43b
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormalHeightOfAnatomicalEntity.tsv
@@ -0,0 +1,3 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0081423
+http://purl.obolibrary.org/obo/UBERON_0000468	http://purl.obolibrary.org/obo/UPHENO_0081424
diff --git a/src/curation/upheno-fillers/mp/abnormalLengthOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/mp/abnormalLengthOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..5dc65675
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormalLengthOfAnatomicalEntity.tsv
@@ -0,0 +1,11 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0084757
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+http://purl.obolibrary.org/obo/UBERON_0002356	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0043197	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/mp/abnormalLevelOfChemicalEntity.tsv b/src/curation/upheno-fillers/mp/abnormalLevelOfChemicalEntity.tsv
new file mode 100644
index 00000000..50b94af9
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormalLevelOfChemicalEntity.tsv
@@ -0,0 +1,116 @@
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+http://purl.obolibrary.org/obo/CHEBI_36526	http://purl.obolibrary.org/obo/UPHENO_0046274
+http://purl.obolibrary.org/obo/PR_000007785	http://purl.obolibrary.org/obo/UPHENO_0046275
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+http://purl.obolibrary.org/obo/PR_000009182	http://purl.obolibrary.org/obo/UPHENO_0046287
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+http://purl.obolibrary.org/obo/CHEBI_36477	http://purl.obolibrary.org/obo/UPHENO_0046375
+http://purl.obolibrary.org/obo/CHEBI_15354	http://purl.obolibrary.org/obo/UPHENO_0084543
+http://purl.obolibrary.org/obo/PR_000016480	http://purl.obolibrary.org/obo/UPHENO_0083890
+http://purl.obolibrary.org/obo/CHEBI_15355	http://purl.obolibrary.org/obo/UPHENO_0046376
diff --git a/src/curation/upheno-fillers/mp/abnormalLevelOfChemicalEntityInLocation.tsv b/src/curation/upheno-fillers/mp/abnormalLevelOfChemicalEntityInLocation.tsv
new file mode 100644
index 00000000..6135e3a9
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormalLevelOfChemicalEntityInLocation.tsv
@@ -0,0 +1,200 @@
+chemical_entity	location	defined_class
+http://purl.obolibrary.org/obo/CHEBI_25017	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0051582
+http://purl.obolibrary.org/obo/CHEBI_18248	http://purl.obolibrary.org/obo/UBERON_0000160	http://purl.obolibrary.org/obo/UPHENO_0051583
+http://purl.obolibrary.org/obo/CHEBI_28087	http://purl.obolibrary.org/obo/UBERON_0002107	http://purl.obolibrary.org/obo/UPHENO_0051584
+http://purl.obolibrary.org/obo/CHEBI_16919	http://purl.obolibrary.org/obo/UBERON_0001088	http://purl.obolibrary.org/obo/UPHENO_0051585
+http://purl.obolibrary.org/obo/CHEBI_24431	http://purl.obolibrary.org/obo/UBERON_0002048	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CHEBI_24431	http://purl.obolibrary.org/obo/UBERON_0001988	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CHEBI_17026	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0051589
+http://purl.obolibrary.org/obo/PR_000000134	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0051590
+http://purl.obolibrary.org/obo/CHEBI_15422	http://purl.obolibrary.org/obo/CL_0000233	http://purl.obolibrary.org/obo/UPHENO_0077803
+http://purl.obolibrary.org/obo/CHEBI_36976	http://purl.obolibrary.org/obo/UBERON_0001088	http://purl.obolibrary.org/obo/UPHENO_0051593
+http://purl.obolibrary.org/obo/CHEBI_33568	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0051594
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+http://purl.obolibrary.org/obo/CHEBI_17754	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0051597
+http://purl.obolibrary.org/obo/CHEBI_17755	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0051599
+http://purl.obolibrary.org/obo/CHEBI_28694	http://purl.obolibrary.org/obo/UBERON_0002298	http://purl.obolibrary.org/obo/UPHENO_0051604
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diff --git a/src/curation/upheno-fillers/mp/abnormalMassDensityOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/mp/abnormalMassDensityOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..58c4ae12
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormalMassDensityOfAnatomicalEntity.tsv
@@ -0,0 +1,3 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0084653
+http://purl.obolibrary.org/obo/UBERON_0001474	http://purl.obolibrary.org/obo/UPHENO_0084654
diff --git a/src/curation/upheno-fillers/mp/abnormalMobilityOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/mp/abnormalMobilityOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..0d80fa2f
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormalMobilityOfAnatomicalEntity.tsv
@@ -0,0 +1,3 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0076943
+http://purl.obolibrary.org/obo/UBERON_0000982	http://purl.obolibrary.org/obo/UPHENO_0076944
diff --git a/src/curation/upheno-fillers/mp/abnormalMorphologyOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/mp/abnormalMorphologyOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..2dc210ae
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormalMorphologyOfAnatomicalEntity.tsv
@@ -0,0 +1,388 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/CL_0000680	http://purl.obolibrary.org/obo/UPHENO_0085519
+http://purl.obolibrary.org/obo/CL_0000681	http://purl.obolibrary.org/obo/UPHENO_0085520
+http://purl.obolibrary.org/obo/CL_0000561	http://purl.obolibrary.org/obo/UPHENO_0085521
+http://purl.obolibrary.org/obo/CL_0000440	http://purl.obolibrary.org/obo/UPHENO_0085522
+http://purl.obolibrary.org/obo/CL_0000442	http://purl.obolibrary.org/obo/UPHENO_0085523
+http://purl.obolibrary.org/obo/CL_0000322	http://purl.obolibrary.org/obo/UPHENO_0085524
+http://purl.obolibrary.org/obo/CL_0000202	http://purl.obolibrary.org/obo/UPHENO_0085525
+http://purl.obolibrary.org/obo/GO_0005815	http://purl.obolibrary.org/obo/UPHENO_0085526
+http://purl.obolibrary.org/obo/GO_0005813	http://purl.obolibrary.org/obo/UPHENO_0085527
+http://purl.obolibrary.org/obo/CL_0000446	http://purl.obolibrary.org/obo/UPHENO_0085528
+http://purl.obolibrary.org/obo/CL_0000567	http://purl.obolibrary.org/obo/UPHENO_0085529
+http://purl.obolibrary.org/obo/CL_0000205	http://purl.obolibrary.org/obo/UPHENO_0085530
+http://purl.obolibrary.org/obo/CL_0000326	http://purl.obolibrary.org/obo/UPHENO_0085531
+http://purl.obolibrary.org/obo/CL_0000206	http://purl.obolibrary.org/obo/UPHENO_0085532
+http://purl.obolibrary.org/obo/CL_0000448	http://purl.obolibrary.org/obo/UPHENO_0085533
+http://purl.obolibrary.org/obo/CL_0000449	http://purl.obolibrary.org/obo/UPHENO_0085534
+http://purl.obolibrary.org/obo/CL_0000207	http://purl.obolibrary.org/obo/UPHENO_0085535
+http://purl.obolibrary.org/obo/CL_0000451	http://purl.obolibrary.org/obo/UPHENO_0085536
+http://purl.obolibrary.org/obo/GO_0033391	http://purl.obolibrary.org/obo/UPHENO_0085537
+http://purl.obolibrary.org/obo/GO_0033270	http://purl.obolibrary.org/obo/UPHENO_0085538
+http://purl.obolibrary.org/obo/CL_0000573	http://purl.obolibrary.org/obo/UPHENO_0085539
+http://purl.obolibrary.org/obo/CL_0000695	http://purl.obolibrary.org/obo/UPHENO_0085540
+http://purl.obolibrary.org/obo/CL_0000453	http://purl.obolibrary.org/obo/UPHENO_0085541
+http://purl.obolibrary.org/obo/CL_0000696	http://purl.obolibrary.org/obo/UPHENO_0085542
+http://purl.obolibrary.org/obo/CL_0000333	http://purl.obolibrary.org/obo/UPHENO_0085543
+http://purl.obolibrary.org/obo/GO_0031091	http://purl.obolibrary.org/obo/UPHENO_0085544
+http://purl.obolibrary.org/obo/CL_0000576	http://purl.obolibrary.org/obo/UPHENO_0085545
+http://purl.obolibrary.org/obo/CL_0002633	http://purl.obolibrary.org/obo/UPHENO_0085546
+http://purl.obolibrary.org/obo/GO_0097208	http://purl.obolibrary.org/obo/UPHENO_0085547
+http://purl.obolibrary.org/obo/CL_0000216	http://purl.obolibrary.org/obo/UPHENO_0085548
+http://purl.obolibrary.org/obo/CL_0002638	http://purl.obolibrary.org/obo/UPHENO_0085549
+http://purl.obolibrary.org/obo/CL_0000218	http://purl.obolibrary.org/obo/UPHENO_0085550
+http://purl.obolibrary.org/obo/GO_0015629	http://purl.obolibrary.org/obo/UPHENO_0085551
+http://purl.obolibrary.org/obo/CL_0000782	http://purl.obolibrary.org/obo/UPHENO_0085552
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+http://purl.obolibrary.org/obo/GO_0035686	http://purl.obolibrary.org/obo/UPHENO_0085554
+http://purl.obolibrary.org/obo/CL_0000541	http://purl.obolibrary.org/obo/UPHENO_0085555
+http://purl.obolibrary.org/obo/CL_0000783	http://purl.obolibrary.org/obo/UPHENO_0085556
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+http://purl.obolibrary.org/obo/CL_0000784	http://purl.obolibrary.org/obo/UPHENO_0085558
+http://purl.obolibrary.org/obo/CL_0000785	http://purl.obolibrary.org/obo/UPHENO_0085559
+http://purl.obolibrary.org/obo/CL_0000786	http://purl.obolibrary.org/obo/UPHENO_0085560
+http://purl.obolibrary.org/obo/GO_0033269	http://purl.obolibrary.org/obo/UPHENO_0085561
+http://purl.obolibrary.org/obo/GO_0033268	http://purl.obolibrary.org/obo/UPHENO_0085562
+http://purl.obolibrary.org/obo/CL_0000545	http://purl.obolibrary.org/obo/UPHENO_0085563
+http://purl.obolibrary.org/obo/CL_0000787	http://purl.obolibrary.org/obo/UPHENO_0085564
+http://purl.obolibrary.org/obo/CL_0000546	http://purl.obolibrary.org/obo/UPHENO_0085565
+http://purl.obolibrary.org/obo/CL_0000788	http://purl.obolibrary.org/obo/UPHENO_0085566
+http://purl.obolibrary.org/obo/CL_0000789	http://purl.obolibrary.org/obo/UPHENO_0085567
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+http://purl.obolibrary.org/obo/GO_0032280	http://purl.obolibrary.org/obo/UPHENO_0085573
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+http://purl.obolibrary.org/obo/GO_0005929	http://purl.obolibrary.org/obo/UPHENO_0077865
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+http://purl.obolibrary.org/obo/GO_0098846	http://purl.obolibrary.org/obo/UPHENO_0085590
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+http://purl.obolibrary.org/obo/GO_0005739	http://purl.obolibrary.org/obo/UPHENO_0085592
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+http://purl.obolibrary.org/obo/GO_0005743	http://purl.obolibrary.org/obo/UPHENO_0085605
+http://purl.obolibrary.org/obo/CL_0000138	http://purl.obolibrary.org/obo/UPHENO_0085606
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+http://purl.obolibrary.org/obo/CL_0000581	http://purl.obolibrary.org/obo/UPHENO_0085609
+http://purl.obolibrary.org/obo/CL_0000583	http://purl.obolibrary.org/obo/UPHENO_0085610
+http://purl.obolibrary.org/obo/GO_0016605	http://purl.obolibrary.org/obo/UPHENO_0085611
+http://purl.obolibrary.org/obo/CL_0000584	http://purl.obolibrary.org/obo/UPHENO_0085612
+http://purl.obolibrary.org/obo/CL_0000100	http://purl.obolibrary.org/obo/UPHENO_0085613
+http://purl.obolibrary.org/obo/GO_0015630	http://purl.obolibrary.org/obo/UPHENO_0085614
+http://purl.obolibrary.org/obo/CL_0000101	http://purl.obolibrary.org/obo/UPHENO_0085615
+http://purl.obolibrary.org/obo/CL_0000586	http://purl.obolibrary.org/obo/UPHENO_0085616
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+http://purl.obolibrary.org/obo/GO_0042827	http://purl.obolibrary.org/obo/UPHENO_0085618
+http://purl.obolibrary.org/obo/GO_0097730	http://purl.obolibrary.org/obo/UPHENO_0085619
+http://purl.obolibrary.org/obo/CL_0000589	http://purl.obolibrary.org/obo/UPHENO_0085620
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+http://purl.obolibrary.org/obo/CL_0000109	http://purl.obolibrary.org/obo/UPHENO_0085624
+http://purl.obolibrary.org/obo/GO_0000262	http://purl.obolibrary.org/obo/UPHENO_0085625
+http://purl.obolibrary.org/obo/GO_0016607	http://purl.obolibrary.org/obo/UPHENO_0085626
+http://purl.obolibrary.org/obo/CL_0000110	http://purl.obolibrary.org/obo/UPHENO_0085627
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+http://purl.obolibrary.org/obo/CL_0000476	http://purl.obolibrary.org/obo/UPHENO_0085632
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+http://purl.obolibrary.org/obo/CL_0000236	http://purl.obolibrary.org/obo/UPHENO_0085634
+http://purl.obolibrary.org/obo/GO_0005604	http://purl.obolibrary.org/obo/UPHENO_0085635
+http://purl.obolibrary.org/obo/GO_0005840	http://purl.obolibrary.org/obo/UPHENO_0085636
+http://purl.obolibrary.org/obo/CL_0002418	http://purl.obolibrary.org/obo/UPHENO_0085637
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+http://purl.obolibrary.org/obo/CL_0000165	http://purl.obolibrary.org/obo/UPHENO_0085640
+http://purl.obolibrary.org/obo/CL_0000287	http://purl.obolibrary.org/obo/UPHENO_0085641
+http://purl.obolibrary.org/obo/CL_0002343	http://purl.obolibrary.org/obo/UPHENO_0085642
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+http://purl.obolibrary.org/obo/CL_0000047	http://purl.obolibrary.org/obo/UPHENO_0085644
+http://purl.obolibrary.org/obo/CL_0000048	http://purl.obolibrary.org/obo/UPHENO_0085645
+http://purl.obolibrary.org/obo/CL_0000169	http://purl.obolibrary.org/obo/UPHENO_0085646
+http://purl.obolibrary.org/obo/CL_0000049	http://purl.obolibrary.org/obo/UPHENO_0085647
+http://purl.obolibrary.org/obo/CL_0000162	http://purl.obolibrary.org/obo/UPHENO_0085648
+http://purl.obolibrary.org/obo/GO_0005777	http://purl.obolibrary.org/obo/UPHENO_0085649
+http://purl.obolibrary.org/obo/GO_0005652	http://purl.obolibrary.org/obo/UPHENO_0085650
+http://purl.obolibrary.org/obo/GO_0005773	http://purl.obolibrary.org/obo/UPHENO_0085651
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/CL_1000488	http://purl.obolibrary.org/obo/UPHENO_0085652
+http://purl.obolibrary.org/obo/CL_0002353	http://purl.obolibrary.org/obo/UPHENO_0085653
+http://purl.obolibrary.org/obo/CL_0000295	http://purl.obolibrary.org/obo/UPHENO_0085654
+http://purl.obolibrary.org/obo/CL_0002355	http://purl.obolibrary.org/obo/UPHENO_0085655
+http://purl.obolibrary.org/obo/CL_0002354	http://purl.obolibrary.org/obo/UPHENO_0085656
+http://purl.obolibrary.org/obo/CL_0000178	http://purl.obolibrary.org/obo/UPHENO_0085657
+http://purl.obolibrary.org/obo/CL_0002357	http://purl.obolibrary.org/obo/UPHENO_0085658
+http://purl.obolibrary.org/obo/CL_1001451	http://purl.obolibrary.org/obo/UPHENO_0085659
+http://purl.obolibrary.org/obo/CL_0000059	http://purl.obolibrary.org/obo/UPHENO_0085660
+http://purl.obolibrary.org/obo/CL_0000050	http://purl.obolibrary.org/obo/UPHENO_0085661
+http://purl.obolibrary.org/obo/CL_0000171	http://purl.obolibrary.org/obo/UPHENO_0085662
+http://purl.obolibrary.org/obo/CL_0000051	http://purl.obolibrary.org/obo/UPHENO_0085663
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+http://purl.obolibrary.org/obo/GO_0005783	http://purl.obolibrary.org/obo/UPHENO_0085665
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+http://purl.obolibrary.org/obo/GO_0001520	http://purl.obolibrary.org/obo/UPHENO_0085893
+http://purl.obolibrary.org/obo/CL_0000633	http://purl.obolibrary.org/obo/UPHENO_0085894
+http://purl.obolibrary.org/obo/CL_0000634	http://purl.obolibrary.org/obo/UPHENO_0085895
+http://purl.obolibrary.org/obo/CL_0000635	http://purl.obolibrary.org/obo/UPHENO_0085896
+http://purl.obolibrary.org/obo/CL_0000636	http://purl.obolibrary.org/obo/UPHENO_0085897
+http://purl.obolibrary.org/obo/CL_0000517	http://purl.obolibrary.org/obo/UPHENO_0085898
diff --git a/src/curation/upheno-fillers/mp/abnormalMorphologyOfAnatomicalEntityInLocation.tsv b/src/curation/upheno-fillers/mp/abnormalMorphologyOfAnatomicalEntityInLocation.tsv
new file mode 100644
index 00000000..126f9594
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormalMorphologyOfAnatomicalEntityInLocation.tsv
@@ -0,0 +1,15 @@
+anatomical_entity	location	defined_class
+http://purl.obolibrary.org/obo/CL_0002204	http://purl.obolibrary.org/obo/UBERON_0004807	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/CL_0002368	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0060091	http://purl.obolibrary.org/obo/CL_0000609	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0002204	http://purl.obolibrary.org/obo/UBERON_0004808	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0007589	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/CL_0000065	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0004807	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0031514	http://purl.obolibrary.org/obo/CL_0002368	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0004808	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/CL_0000609	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0031514	http://purl.obolibrary.org/obo/CL_0000065	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0031514	http://purl.obolibrary.org/obo/UBERON_0007589	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0015813	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000160	http://purl.obolibrary.org/obo/UBERON_0015813	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/mp/abnormalMorphologyOfCellularComponent.tsv b/src/curation/upheno-fillers/mp/abnormalMorphologyOfCellularComponent.tsv
new file mode 100644
index 00000000..9e10bf43
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormalMorphologyOfCellularComponent.tsv
@@ -0,0 +1,89 @@
+cellular_component	defined_class
+http://purl.obolibrary.org/obo/GO_0043197	http://purl.obolibrary.org/obo/UPHENO_0067636
+http://purl.obolibrary.org/obo/GO_0000262	http://purl.obolibrary.org/obo/UPHENO_0067637
+http://purl.obolibrary.org/obo/GO_0042383	http://purl.obolibrary.org/obo/UPHENO_0067638
+http://purl.obolibrary.org/obo/GO_0016529	http://purl.obolibrary.org/obo/UPHENO_0067639
+http://purl.obolibrary.org/obo/GO_0016607	http://purl.obolibrary.org/obo/UPHENO_0067640
+http://purl.obolibrary.org/obo/GO_0008021	http://purl.obolibrary.org/obo/UPHENO_0067641
+http://purl.obolibrary.org/obo/GO_0005794	http://purl.obolibrary.org/obo/UPHENO_0067642
+http://purl.obolibrary.org/obo/GO_0005795	http://purl.obolibrary.org/obo/UPHENO_0067643
+http://purl.obolibrary.org/obo/GO_0014704	http://purl.obolibrary.org/obo/UPHENO_0067644
+http://purl.obolibrary.org/obo/GO_0005634	http://purl.obolibrary.org/obo/UPHENO_0067645
+http://purl.obolibrary.org/obo/GO_0001750	http://purl.obolibrary.org/obo/UPHENO_0067646
+http://purl.obolibrary.org/obo/GO_0060091	http://purl.obolibrary.org/obo/UPHENO_0067647
+http://purl.obolibrary.org/obo/GO_0005759	http://purl.obolibrary.org/obo/UPHENO_0067648
+http://purl.obolibrary.org/obo/GO_0097730	http://purl.obolibrary.org/obo/UPHENO_0067649
+http://purl.obolibrary.org/obo/GO_0043195	http://purl.obolibrary.org/obo/UPHENO_0067650
+http://purl.obolibrary.org/obo/GO_0000781	http://purl.obolibrary.org/obo/UPHENO_0067651
+http://purl.obolibrary.org/obo/GO_0043194	http://purl.obolibrary.org/obo/UPHENO_0067652
+http://purl.obolibrary.org/obo/GO_0036053	http://purl.obolibrary.org/obo/UPHENO_0067653
+http://purl.obolibrary.org/obo/GO_0042827	http://purl.obolibrary.org/obo/UPHENO_0067654
+http://purl.obolibrary.org/obo/GO_0015030	http://purl.obolibrary.org/obo/UPHENO_0067655
+http://purl.obolibrary.org/obo/GO_0030673	http://purl.obolibrary.org/obo/UPHENO_0067656
+http://purl.obolibrary.org/obo/GO_0033269	http://purl.obolibrary.org/obo/UPHENO_0067657
+http://purl.obolibrary.org/obo/GO_0033268	http://purl.obolibrary.org/obo/UPHENO_0067658
+http://purl.obolibrary.org/obo/GO_0061827	http://purl.obolibrary.org/obo/UPHENO_0084414
+http://purl.obolibrary.org/obo/GO_0015630	http://purl.obolibrary.org/obo/UPHENO_0067659
+http://purl.obolibrary.org/obo/GO_0014069	http://purl.obolibrary.org/obo/UPHENO_0067660
+http://purl.obolibrary.org/obo/GO_0016605	http://purl.obolibrary.org/obo/UPHENO_0067661
+http://purl.obolibrary.org/obo/GO_0035686	http://purl.obolibrary.org/obo/UPHENO_0067662
+http://purl.obolibrary.org/obo/GO_0042470	http://purl.obolibrary.org/obo/UPHENO_0067663
+http://purl.obolibrary.org/obo/GO_0043005	http://purl.obolibrary.org/obo/UPHENO_0067664
+http://purl.obolibrary.org/obo/GO_0097381	http://purl.obolibrary.org/obo/UPHENO_0067665
+http://purl.obolibrary.org/obo/GO_0030424	http://purl.obolibrary.org/obo/UPHENO_0067666
+http://purl.obolibrary.org/obo/GO_0002177	http://purl.obolibrary.org/obo/UPHENO_0067667
+http://purl.obolibrary.org/obo/GO_0005886	http://purl.obolibrary.org/obo/UPHENO_0067668
+http://purl.obolibrary.org/obo/GO_0030425	http://purl.obolibrary.org/obo/UPHENO_0067669
+http://purl.obolibrary.org/obo/GO_0031514	http://purl.obolibrary.org/obo/UPHENO_0067670
+http://purl.obolibrary.org/obo/GO_0005840	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0005764	http://purl.obolibrary.org/obo/UPHENO_0067671
+http://purl.obolibrary.org/obo/GO_0001520	http://purl.obolibrary.org/obo/UPHENO_0084415
+http://purl.obolibrary.org/obo/GO_0005604	http://purl.obolibrary.org/obo/UPHENO_0067672
+http://purl.obolibrary.org/obo/GO_0097226	http://purl.obolibrary.org/obo/UPHENO_0067674
+http://purl.obolibrary.org/obo/GO_0031594	http://purl.obolibrary.org/obo/UPHENO_0067675
+http://purl.obolibrary.org/obo/GO_0097225	http://purl.obolibrary.org/obo/UPHENO_0067676
+http://purl.obolibrary.org/obo/GO_0097228	http://purl.obolibrary.org/obo/UPHENO_0067677
+http://purl.obolibrary.org/obo/GO_0097227	http://purl.obolibrary.org/obo/UPHENO_0067678
+http://purl.obolibrary.org/obo/GO_0031674	http://purl.obolibrary.org/obo/UPHENO_0067679
+http://purl.obolibrary.org/obo/GO_0097229	http://purl.obolibrary.org/obo/UPHENO_0067680
+http://purl.obolibrary.org/obo/GO_0031672	http://purl.obolibrary.org/obo/UPHENO_0067681
+http://purl.obolibrary.org/obo/GO_0031430	http://purl.obolibrary.org/obo/UPHENO_0067682
+http://purl.obolibrary.org/obo/GO_0005929	http://purl.obolibrary.org/obo/UPHENO_0067683
+http://purl.obolibrary.org/obo/GO_0031673	http://purl.obolibrary.org/obo/UPHENO_0067684
+http://purl.obolibrary.org/obo/GO_0043209	http://purl.obolibrary.org/obo/UPHENO_0067685
+http://purl.obolibrary.org/obo/GO_0030061	http://purl.obolibrary.org/obo/UPHENO_0067686
+http://purl.obolibrary.org/obo/GO_0036126	http://purl.obolibrary.org/obo/UPHENO_0067687
+http://purl.obolibrary.org/obo/GO_0032280	http://purl.obolibrary.org/obo/UPHENO_0067688
+http://purl.obolibrary.org/obo/GO_0060076	http://purl.obolibrary.org/obo/UPHENO_0067689
+http://purl.obolibrary.org/obo/GO_0060077	http://purl.obolibrary.org/obo/UPHENO_0067690
+http://purl.obolibrary.org/obo/GO_0005575	http://purl.obolibrary.org/obo/UPHENO_0067691
+http://purl.obolibrary.org/obo/GO_0005652	http://purl.obolibrary.org/obo/UPHENO_0067692
+http://purl.obolibrary.org/obo/GO_0005773	http://purl.obolibrary.org/obo/UPHENO_0067693
+http://purl.obolibrary.org/obo/GO_0005694	http://purl.obolibrary.org/obo/UPHENO_0067694
+http://purl.obolibrary.org/obo/GO_0044224	http://purl.obolibrary.org/obo/UPHENO_0067695
+http://purl.obolibrary.org/obo/GO_0030017	http://purl.obolibrary.org/obo/UPHENO_0067696
+http://purl.obolibrary.org/obo/GO_0030018	http://purl.obolibrary.org/obo/UPHENO_0067697
+http://purl.obolibrary.org/obo/GO_0032437	http://purl.obolibrary.org/obo/UPHENO_0067698
+http://purl.obolibrary.org/obo/GO_0005777	http://purl.obolibrary.org/obo/UPHENO_0067699
+http://purl.obolibrary.org/obo/GO_0097470	http://purl.obolibrary.org/obo/UPHENO_0067700
+http://purl.obolibrary.org/obo/GO_0005730	http://purl.obolibrary.org/obo/UPHENO_0067701
+http://purl.obolibrary.org/obo/GO_0031985	http://purl.obolibrary.org/obo/UPHENO_0067702
+http://purl.obolibrary.org/obo/GO_0005813	http://purl.obolibrary.org/obo/UPHENO_0067703
+http://purl.obolibrary.org/obo/GO_0001533	http://purl.obolibrary.org/obo/UPHENO_0067704
+http://purl.obolibrary.org/obo/GO_0005856	http://purl.obolibrary.org/obo/UPHENO_0067705
+http://purl.obolibrary.org/obo/GO_0005815	http://purl.obolibrary.org/obo/UPHENO_0067706
+http://purl.obolibrary.org/obo/GO_0005739	http://purl.obolibrary.org/obo/UPHENO_0067707
+http://purl.obolibrary.org/obo/GO_0032279	http://purl.obolibrary.org/obo/UPHENO_0067708
+http://purl.obolibrary.org/obo/GO_0098846	http://purl.obolibrary.org/obo/UPHENO_0067709
+http://purl.obolibrary.org/obo/GO_0032391	http://purl.obolibrary.org/obo/UPHENO_0067710
+http://purl.obolibrary.org/obo/GO_0015629	http://purl.obolibrary.org/obo/UPHENO_0067711
+http://purl.obolibrary.org/obo/GO_0005783	http://purl.obolibrary.org/obo/UPHENO_0067712
+http://purl.obolibrary.org/obo/GO_0045202	http://purl.obolibrary.org/obo/UPHENO_0067713
+http://purl.obolibrary.org/obo/GO_0005743	http://purl.obolibrary.org/obo/UPHENO_0067714
+http://purl.obolibrary.org/obo/GO_0001669	http://purl.obolibrary.org/obo/UPHENO_0067716
+http://purl.obolibrary.org/obo/GO_0097208	http://purl.obolibrary.org/obo/UPHENO_0067717
+http://purl.obolibrary.org/obo/GO_0031012	http://purl.obolibrary.org/obo/UPHENO_0067718
+http://purl.obolibrary.org/obo/GO_0031091	http://purl.obolibrary.org/obo/UPHENO_0067719
+http://purl.obolibrary.org/obo/GO_0043229	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0033391	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0033270	http://purl.obolibrary.org/obo/UPHENO_0067720
diff --git a/src/curation/upheno-fillers/mp/abnormalMorphologyOfPartOfAnatomicalEntity-modified.tsv b/src/curation/upheno-fillers/mp/abnormalMorphologyOfPartOfAnatomicalEntity-modified.tsv
new file mode 100644
index 00000000..f1401765
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormalMorphologyOfPartOfAnatomicalEntity-modified.tsv
@@ -0,0 +1,388 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/CL_0000680	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000681	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000561	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000440	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000442	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000322	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000202	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0005815	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0005813	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000446	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000567	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000205	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000326	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000206	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000448	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000449	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000207	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000451	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0033391	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0033270	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000573	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000695	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000453	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000696	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000333	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0031091	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000576	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0002633	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0097208	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000216	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0002638	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000218	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0015629	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000782	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000540	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0035686	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000541	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000783	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000542	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000784	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000785	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000786	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0033269	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0033268	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000545	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000787	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000546	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000788	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000789	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000547	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000669	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000670	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000792	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000793	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0032280	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000794	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000795	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000553	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000796	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000312	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000797	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0005929	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000798	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000556	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000557	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000679	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000437	http://purl.obolibrary.org/obo/UPHENO_0084757
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diff --git a/src/curation/upheno-fillers/mp/abnormalMorphologyOfPartOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/mp/abnormalMorphologyOfPartOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..7c8293e3
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormalMorphologyOfPartOfAnatomicalEntity.tsv
@@ -0,0 +1,1821 @@
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diff --git a/src/curation/upheno-fillers/mp/abnormalNumberOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/mp/abnormalNumberOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..ccebebb3
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormalNumberOfAnatomicalEntity.tsv
@@ -0,0 +1,125 @@
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+http://purl.obolibrary.org/obo/GO_0008021	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0002496	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0002495	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000232	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000233	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000510	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000235	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000236	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0002092	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0000035	http://purl.obolibrary.org/obo/UPHENO_0011577
+http://purl.obolibrary.org/obo/UBERON_0000036	http://purl.obolibrary.org/obo/UPHENO_0084728
+http://purl.obolibrary.org/obo/CL_0002490	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0000037	http://purl.obolibrary.org/obo/UPHENO_0011579
+http://purl.obolibrary.org/obo/UBERON_0002336	http://purl.obolibrary.org/obo/UPHENO_0011580
+http://purl.obolibrary.org/obo/UBERON_0002451	http://purl.obolibrary.org/obo/UPHENO_0011581
+http://purl.obolibrary.org/obo/CL_0000916	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0000029	http://purl.obolibrary.org/obo/UPHENO_0011583
+http://purl.obolibrary.org/obo/UBERON_0001911	http://purl.obolibrary.org/obo/UPHENO_0011584
+http://purl.obolibrary.org/obo/UBERON_0002208	http://purl.obolibrary.org/obo/UPHENO_0011585
+http://purl.obolibrary.org/obo/CL_0002418	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000911	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000912	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/mp/abnormalNumberOfAnatomicalEntityInLocation.tsv b/src/curation/upheno-fillers/mp/abnormalNumberOfAnatomicalEntityInLocation.tsv
new file mode 100644
index 00000000..89712aaa
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormalNumberOfAnatomicalEntityInLocation.tsv
@@ -0,0 +1,9 @@
+anatomical_entity	location	defined_class
+http://purl.obolibrary.org/obo/GO_0005811	http://purl.obolibrary.org/obo/UBERON_0001348	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001232	http://purl.obolibrary.org/obo/UBERON_0002113	http://purl.obolibrary.org/obo/UPHENO_0006907
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0001348	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0002113	http://purl.obolibrary.org/obo/UPHENO_0006911
+http://purl.obolibrary.org/obo/CL_0000763	http://purl.obolibrary.org/obo/UBERON_0002371	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0015813	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000160	http://purl.obolibrary.org/obo/UBERON_0015813	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0002371	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/mp/abnormalNumberOfCellularComponent.tsv b/src/curation/upheno-fillers/mp/abnormalNumberOfCellularComponent.tsv
new file mode 100644
index 00000000..12f1e008
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormalNumberOfCellularComponent.tsv
@@ -0,0 +1,12 @@
+cellular_component	defined_class
+http://purl.obolibrary.org/obo/GO_0043197	http://purl.obolibrary.org/obo/UPHENO_0083891
+http://purl.obolibrary.org/obo/GO_0042827	http://purl.obolibrary.org/obo/UPHENO_0046180
+http://purl.obolibrary.org/obo/GO_0008021	http://purl.obolibrary.org/obo/UPHENO_0077337
+http://purl.obolibrary.org/obo/GO_0005575	http://purl.obolibrary.org/obo/UPHENO_0046183
+http://purl.obolibrary.org/obo/GO_0002185	http://purl.obolibrary.org/obo/UPHENO_0046184
+http://purl.obolibrary.org/obo/GO_0005694	http://purl.obolibrary.org/obo/UPHENO_0077386
+http://purl.obolibrary.org/obo/GO_0005634	http://purl.obolibrary.org/obo/UPHENO_0046185
+http://purl.obolibrary.org/obo/GO_0031091	http://purl.obolibrary.org/obo/UPHENO_0046186
+http://purl.obolibrary.org/obo/GO_0042613	http://purl.obolibrary.org/obo/UPHENO_0046187
+http://purl.obolibrary.org/obo/GO_0001750	http://purl.obolibrary.org/obo/UPHENO_0046188
+http://purl.obolibrary.org/obo/GO_0042612	http://purl.obolibrary.org/obo/UPHENO_0046189
diff --git a/src/curation/upheno-fillers/mp/abnormalPositionOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/mp/abnormalPositionOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..92aa9c86
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormalPositionOfAnatomicalEntity.tsv
@@ -0,0 +1,42 @@
+entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0004277	http://purl.obolibrary.org/obo/UPHENO_0018381
+http://purl.obolibrary.org/obo/UBERON_0000056	http://purl.obolibrary.org/obo/UPHENO_0018382
+http://purl.obolibrary.org/obo/UBERON_0005487	http://purl.obolibrary.org/obo/UPHENO_0018383
+http://purl.obolibrary.org/obo/UBERON_0001264	http://purl.obolibrary.org/obo/UPHENO_0018384
+http://purl.obolibrary.org/obo/UBERON_0001043	http://purl.obolibrary.org/obo/UPHENO_0018385
+http://purl.obolibrary.org/obo/UBERON_0002259	http://purl.obolibrary.org/obo/UPHENO_0018387
+http://purl.obolibrary.org/obo/UBERON_0000992	http://purl.obolibrary.org/obo/UPHENO_0018388
+http://purl.obolibrary.org/obo/UBERON_0002114	http://purl.obolibrary.org/obo/UPHENO_0018389
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0018390
+http://purl.obolibrary.org/obo/UBERON_0002370	http://purl.obolibrary.org/obo/UPHENO_0018391
+http://purl.obolibrary.org/obo/UBERON_0013765	http://purl.obolibrary.org/obo/UPHENO_0018392
+http://purl.obolibrary.org/obo/UBERON_0000965	http://purl.obolibrary.org/obo/UPHENO_0018393
+http://purl.obolibrary.org/obo/UBERON_0001514	http://purl.obolibrary.org/obo/UPHENO_0018394
+http://purl.obolibrary.org/obo/UBERON_0001535	http://purl.obolibrary.org/obo/UPHENO_0018396
+http://purl.obolibrary.org/obo/UBERON_0000948	http://purl.obolibrary.org/obo/UPHENO_0018397
+http://purl.obolibrary.org/obo/UBERON_0000945	http://purl.obolibrary.org/obo/UPHENO_0018398
+http://purl.obolibrary.org/obo/UBERON_0001759	http://purl.obolibrary.org/obo/UPHENO_0018399
+http://purl.obolibrary.org/obo/UBERON_0000044	http://purl.obolibrary.org/obo/UPHENO_0018400
+http://purl.obolibrary.org/obo/UBERON_0002223	http://purl.obolibrary.org/obo/UPHENO_0018401
+http://purl.obolibrary.org/obo/UBERON_0001650	http://purl.obolibrary.org/obo/UPHENO_0018402
+http://purl.obolibrary.org/obo/UBERON_0002101	http://purl.obolibrary.org/obo/UPHENO_0018403
+http://purl.obolibrary.org/obo/UBERON_0001771	http://purl.obolibrary.org/obo/UPHENO_0018404
+http://purl.obolibrary.org/obo/UBERON_0006345	http://purl.obolibrary.org/obo/UPHENO_0018405
+http://purl.obolibrary.org/obo/UBERON_0001594	http://purl.obolibrary.org/obo/UPHENO_0018406
+http://purl.obolibrary.org/obo/UBERON_0001473	http://purl.obolibrary.org/obo/UPHENO_0018407
+http://purl.obolibrary.org/obo/UBERON_0003499	http://purl.obolibrary.org/obo/UPHENO_0018408
+http://purl.obolibrary.org/obo/UBERON_0001153	http://purl.obolibrary.org/obo/UPHENO_0082551
+http://purl.obolibrary.org/obo/UBERON_0002066	http://purl.obolibrary.org/obo/UPHENO_0018409
+http://purl.obolibrary.org/obo/UBERON_0001138	http://purl.obolibrary.org/obo/UPHENO_0018410
+http://purl.obolibrary.org/obo/UBERON_0001532	http://purl.obolibrary.org/obo/UPHENO_0018411
+http://purl.obolibrary.org/obo/UBERON_0002083	http://purl.obolibrary.org/obo/UPHENO_0018412
+http://purl.obolibrary.org/obo/UBERON_0003074	http://purl.obolibrary.org/obo/UPHENO_0018413
+http://purl.obolibrary.org/obo/UBERON_0001691	http://purl.obolibrary.org/obo/UPHENO_0018414
+http://purl.obolibrary.org/obo/UBERON_0003890	http://purl.obolibrary.org/obo/UPHENO_0018415
+http://purl.obolibrary.org/obo/UBERON_0001072	http://purl.obolibrary.org/obo/UPHENO_0018416
+http://purl.obolibrary.org/obo/UBERON_0000160	http://purl.obolibrary.org/obo/UPHENO_0018417
+http://purl.obolibrary.org/obo/UBERON_0000019	http://purl.obolibrary.org/obo/UPHENO_0018418
+http://purl.obolibrary.org/obo/UBERON_0001647	http://purl.obolibrary.org/obo/UPHENO_0018419
+http://purl.obolibrary.org/obo/UBERON_0001723	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001887	http://purl.obolibrary.org/obo/UPHENO_0018420
+http://purl.obolibrary.org/obo/UBERON_0002415	http://purl.obolibrary.org/obo/UPHENO_0018421
diff --git a/src/curation/upheno-fillers/mp/abnormalRateOfBiologicalProcess.tsv b/src/curation/upheno-fillers/mp/abnormalRateOfBiologicalProcess.tsv
new file mode 100644
index 00000000..fe758b82
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormalRateOfBiologicalProcess.tsv
@@ -0,0 +1,5 @@
+biological_process	defined_class
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UPHENO_0080377
+http://purl.obolibrary.org/obo/GO_0003094	http://purl.obolibrary.org/obo/UPHENO_0080378
+http://purl.obolibrary.org/obo/GO_0097205	http://purl.obolibrary.org/obo/UPHENO_0080379
+http://purl.obolibrary.org/obo/GO_0008015	http://purl.obolibrary.org/obo/UPHENO_0080380
diff --git a/src/curation/upheno-fillers/mp/abnormalRateOfBiologicalProcessInLocation.tsv b/src/curation/upheno-fillers/mp/abnormalRateOfBiologicalProcessInLocation.tsv
new file mode 100644
index 00000000..ddb82774
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormalRateOfBiologicalProcessInLocation.tsv
@@ -0,0 +1,9 @@
+biological_process	location	defined_class
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0001621	http://purl.obolibrary.org/obo/UPHENO_0084416
+http://purl.obolibrary.org/obo/GO_0008015	http://purl.obolibrary.org/obo/UBERON_0001869	http://purl.obolibrary.org/obo/UPHENO_0080219
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0000955	http://purl.obolibrary.org/obo/UPHENO_0080220
+http://purl.obolibrary.org/obo/GO_0008015	http://purl.obolibrary.org/obo/UBERON_0002113	http://purl.obolibrary.org/obo/UPHENO_0080222
+http://purl.obolibrary.org/obo/GO_0008015	http://purl.obolibrary.org/obo/UBERON_0001621	http://purl.obolibrary.org/obo/UPHENO_0084417
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0001869	http://purl.obolibrary.org/obo/UPHENO_0080223
+http://purl.obolibrary.org/obo/GO_0008015	http://purl.obolibrary.org/obo/UBERON_0000955	http://purl.obolibrary.org/obo/UPHENO_0080224
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0002113	http://purl.obolibrary.org/obo/UPHENO_0080226
diff --git a/src/curation/upheno-fillers/mp/abnormalShapeOfAnatomicalEntityByShapeType.tsv b/src/curation/upheno-fillers/mp/abnormalShapeOfAnatomicalEntityByShapeType.tsv
new file mode 100644
index 00000000..bf9bb275
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormalShapeOfAnatomicalEntityByShapeType.tsv
@@ -0,0 +1,258 @@
+entity	shape	defined_class
+http://purl.obolibrary.org/obo/UBERON_0008200	http://purl.obolibrary.org/obo/PATO_0000407	http://purl.obolibrary.org/obo/UPHENO_0041025
+http://purl.obolibrary.org/obo/UBERON_0000941	http://purl.obolibrary.org/obo/PATO_0001857	http://purl.obolibrary.org/obo/UPHENO_0041026
+http://purl.obolibrary.org/obo/UBERON_0010166	http://purl.obolibrary.org/obo/PATO_0001410	http://purl.obolibrary.org/obo/UPHENO_0041027
+http://purl.obolibrary.org/obo/UBERON_0000979	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0041028
+http://purl.obolibrary.org/obo/UBERON_0000948	http://purl.obolibrary.org/obo/PATO_0000403	http://purl.obolibrary.org/obo/UPHENO_0041029
+http://purl.obolibrary.org/obo/UBERON_0008340	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0041030
+http://purl.obolibrary.org/obo/UBERON_0002134	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0041031
+http://purl.obolibrary.org/obo/UBERON_0004085	http://purl.obolibrary.org/obo/PATO_0000407	http://purl.obolibrary.org/obo/UPHENO_0041032
+http://purl.obolibrary.org/obo/UBERON_0000995	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0041033
+http://purl.obolibrary.org/obo/UBERON_0012128	http://purl.obolibrary.org/obo/PATO_0000403	http://purl.obolibrary.org/obo/UPHENO_0041034
+http://purl.obolibrary.org/obo/UBERON_0002470	http://purl.obolibrary.org/obo/PATO_0001883	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0005396	http://purl.obolibrary.org/obo/PATO_0001798	http://purl.obolibrary.org/obo/UPHENO_0081390
+http://purl.obolibrary.org/obo/UBERON_0001041	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0041035
+http://purl.obolibrary.org/obo/UBERON_0001288	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0041036
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0001848	http://purl.obolibrary.org/obo/UPHENO_0041037
+http://purl.obolibrary.org/obo/UBERON_0000975	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0041038
+http://purl.obolibrary.org/obo/UBERON_0000976	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0041039
+http://purl.obolibrary.org/obo/UBERON_0002412	http://purl.obolibrary.org/obo/PATO_0001786	http://purl.obolibrary.org/obo/UPHENO_0041040
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0002254	http://purl.obolibrary.org/obo/UPHENO_0041041
+http://purl.obolibrary.org/obo/UBERON_0002137	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0041042
+http://purl.obolibrary.org/obo/UBERON_0001049	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0041043
+http://purl.obolibrary.org/obo/UBERON_0011933	http://purl.obolibrary.org/obo/PATO_0001798	http://purl.obolibrary.org/obo/UPHENO_0041044
+http://purl.obolibrary.org/obo/UBERON_0000033	http://purl.obolibrary.org/obo/PATO_0000411	http://purl.obolibrary.org/obo/UPHENO_0041045
+http://purl.obolibrary.org/obo/UBERON_0000033	http://purl.obolibrary.org/obo/PATO_0000407	http://purl.obolibrary.org/obo/UPHENO_0041046
+http://purl.obolibrary.org/obo/UBERON_0001049	http://purl.obolibrary.org/obo/PATO_0000967	http://purl.obolibrary.org/obo/UPHENO_0041047
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0001950	http://purl.obolibrary.org/obo/UPHENO_0041048
+http://purl.obolibrary.org/obo/UBERON_0001424	http://purl.obolibrary.org/obo/PATO_0001592	http://purl.obolibrary.org/obo/UPHENO_0041049
+http://purl.obolibrary.org/obo/UBERON_0005356	http://purl.obolibrary.org/obo/PATO_0001784	http://purl.obolibrary.org/obo/UPHENO_0041050
+http://purl.obolibrary.org/obo/UBERON_0001153	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0041051
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0001154	http://purl.obolibrary.org/obo/UPHENO_0041052
+http://purl.obolibrary.org/obo/UBERON_0000964	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0041053
+http://purl.obolibrary.org/obo/UBERON_0007812	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0041054
+http://purl.obolibrary.org/obo/UBERON_0002228	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0041055
+http://purl.obolibrary.org/obo/UBERON_0001037	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0041056
+http://purl.obolibrary.org/obo/UBERON_0002488	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0041058
+http://purl.obolibrary.org/obo/UBERON_0000981	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0041059
+http://purl.obolibrary.org/obo/UBERON_0001423	http://purl.obolibrary.org/obo/PATO_0001592	http://purl.obolibrary.org/obo/UPHENO_0041060
+http://purl.obolibrary.org/obo/UBERON_0001037	http://purl.obolibrary.org/obo/PATO_0000967	http://purl.obolibrary.org/obo/UPHENO_0041061
+http://purl.obolibrary.org/obo/UBERON_0004085	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0041062
+http://purl.obolibrary.org/obo/UBERON_0010511	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0041063
+http://purl.obolibrary.org/obo/UBERON_0001860	http://purl.obolibrary.org/obo/PATO_0000936	http://purl.obolibrary.org/obo/UPHENO_0041064
+http://purl.obolibrary.org/obo/UBERON_0010512	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0041065
+http://purl.obolibrary.org/obo/UBERON_0010513	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0041066
+http://purl.obolibrary.org/obo/UBERON_0007812	http://purl.obolibrary.org/obo/PATO_0000967	http://purl.obolibrary.org/obo/UPHENO_0041067
+http://purl.obolibrary.org/obo/UBERON_0001092	http://purl.obolibrary.org/obo/PATO_0001784	http://purl.obolibrary.org/obo/UPHENO_0041068
+http://purl.obolibrary.org/obo/UBERON_0001093	http://purl.obolibrary.org/obo/PATO_0001784	http://purl.obolibrary.org/obo/UPHENO_0041069
+http://purl.obolibrary.org/obo/UBERON_0001130	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0041070
+http://purl.obolibrary.org/obo/UBERON_0001264	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0041071
+http://purl.obolibrary.org/obo/UBERON_0005620	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0041072
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+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0001865	http://purl.obolibrary.org/obo/UPHENO_0042700
+http://purl.obolibrary.org/obo/UBERON_0001300	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0041190
+http://purl.obolibrary.org/obo/UBERON_0002113	http://purl.obolibrary.org/obo/PATO_0001786	http://purl.obolibrary.org/obo/UPHENO_0041191
+http://purl.obolibrary.org/obo/UBERON_0006618	http://purl.obolibrary.org/obo/PATO_0000403	http://purl.obolibrary.org/obo/UPHENO_0041192
+http://purl.obolibrary.org/obo/UBERON_0001723	http://purl.obolibrary.org/obo/PATO_0000403	http://purl.obolibrary.org/obo/UPHENO_0041193
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0002170	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002544	http://purl.obolibrary.org/obo/PATO_0000936	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0002171	http://purl.obolibrary.org/obo/UPHENO_0042425
+http://purl.obolibrary.org/obo/UBERON_0002328	http://purl.obolibrary.org/obo/PATO_0001786	http://purl.obolibrary.org/obo/UPHENO_0041194
+http://purl.obolibrary.org/obo/UBERON_0001049	http://purl.obolibrary.org/obo/PATO_0001798	http://purl.obolibrary.org/obo/UPHENO_0041195
+http://purl.obolibrary.org/obo/UBERON_0001759	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0041196
+http://purl.obolibrary.org/obo/UBERON_0010510	http://purl.obolibrary.org/obo/PATO_0001592	http://purl.obolibrary.org/obo/UPHENO_0041197
+http://purl.obolibrary.org/obo/UBERON_0000947	http://purl.obolibrary.org/obo/PATO_0001786	http://purl.obolibrary.org/obo/UPHENO_0041198
+http://purl.obolibrary.org/obo/UBERON_0000996	http://purl.obolibrary.org/obo/PATO_0000403	http://purl.obolibrary.org/obo/UPHENO_0041199
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0000405	http://purl.obolibrary.org/obo/UPHENO_0041200
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0002021	http://purl.obolibrary.org/obo/UPHENO_0041201
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0001857	http://purl.obolibrary.org/obo/UPHENO_0041202
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0000407	http://purl.obolibrary.org/obo/UPHENO_0041203
+http://purl.obolibrary.org/obo/GO_0061827	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0000402	http://purl.obolibrary.org/obo/UPHENO_0041204
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0000403	http://purl.obolibrary.org/obo/UPHENO_0041205
+http://purl.obolibrary.org/obo/UBERON_0001637	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0081397
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0000404	http://purl.obolibrary.org/obo/UPHENO_0041206
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0002281	http://purl.obolibrary.org/obo/UPHENO_0041207
+http://purl.obolibrary.org/obo/UBERON_0001508	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0041208
+http://purl.obolibrary.org/obo/UBERON_0007812	http://purl.obolibrary.org/obo/PATO_0001798	http://purl.obolibrary.org/obo/UPHENO_0041209
+http://purl.obolibrary.org/obo/UBERON_0001037	http://purl.obolibrary.org/obo/PATO_0001799	http://purl.obolibrary.org/obo/UPHENO_0041210
+http://purl.obolibrary.org/obo/UBERON_0001264	http://purl.obolibrary.org/obo/PATO_0002539	http://purl.obolibrary.org/obo/UPHENO_0041211
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0001883	http://purl.obolibrary.org/obo/UPHENO_0041212
+http://purl.obolibrary.org/obo/UBERON_0001640	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0041213
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0001649	http://purl.obolibrary.org/obo/UPHENO_0041214
+http://purl.obolibrary.org/obo/GO_0036126	http://purl.obolibrary.org/obo/PATO_0000404	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000232	http://purl.obolibrary.org/obo/PATO_0001499	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0000995	http://purl.obolibrary.org/obo/PATO_0000403	http://purl.obolibrary.org/obo/UPHENO_0041215
+http://purl.obolibrary.org/obo/UBERON_0001737	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0041216
+http://purl.obolibrary.org/obo/UBERON_0002146	http://purl.obolibrary.org/obo/PATO_0002281	http://purl.obolibrary.org/obo/UPHENO_0041217
+http://purl.obolibrary.org/obo/UBERON_0001759	http://purl.obolibrary.org/obo/PATO_0002254	http://purl.obolibrary.org/obo/UPHENO_0041218
+http://purl.obolibrary.org/obo/UBERON_0001834	http://purl.obolibrary.org/obo/PATO_0002171	http://purl.obolibrary.org/obo/UPHENO_0084757
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+http://purl.obolibrary.org/obo/UBERON_0002205	http://purl.obolibrary.org/obo/PATO_0001786	http://purl.obolibrary.org/obo/UPHENO_0041220
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0002169	http://purl.obolibrary.org/obo/UPHENO_0041414
+http://purl.obolibrary.org/obo/UBERON_0001834	http://purl.obolibrary.org/obo/PATO_0002170	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0001875	http://purl.obolibrary.org/obo/UPHENO_0041221
+http://purl.obolibrary.org/obo/UBERON_0000947	http://purl.obolibrary.org/obo/PATO_0001798	http://purl.obolibrary.org/obo/UPHENO_0081398
+http://purl.obolibrary.org/obo/UBERON_0002488	http://purl.obolibrary.org/obo/PATO_0001857	http://purl.obolibrary.org/obo/UPHENO_0041222
+http://purl.obolibrary.org/obo/UBERON_0007812	http://purl.obolibrary.org/obo/PATO_0000405	http://purl.obolibrary.org/obo/UPHENO_0041223
+http://purl.obolibrary.org/obo/UBERON_0002415	http://purl.obolibrary.org/obo/PATO_0001784	http://purl.obolibrary.org/obo/UPHENO_0041224
+http://purl.obolibrary.org/obo/UBERON_0003128	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0041225
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0041226
+http://purl.obolibrary.org/obo/UBERON_0001860	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0041227
+http://purl.obolibrary.org/obo/UBERON_0001834	http://purl.obolibrary.org/obo/PATO_0002169	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001723	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0041228
+http://purl.obolibrary.org/obo/UBERON_0001844	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0041229
+http://purl.obolibrary.org/obo/UBERON_0008340	http://purl.obolibrary.org/obo/PATO_0000407	http://purl.obolibrary.org/obo/UPHENO_0041230
+http://purl.obolibrary.org/obo/UBERON_0006618	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0041231
+http://purl.obolibrary.org/obo/UBERON_0001153	http://purl.obolibrary.org/obo/PATO_0000404	http://purl.obolibrary.org/obo/UPHENO_0041232
+http://purl.obolibrary.org/obo/UBERON_0000996	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0041233
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0000617	http://purl.obolibrary.org/obo/UPHENO_0041234
+http://purl.obolibrary.org/obo/UBERON_0001620	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0081399
+http://purl.obolibrary.org/obo/UBERON_0001640	http://purl.obolibrary.org/obo/PATO_0002254	http://purl.obolibrary.org/obo/UPHENO_0041235
+http://purl.obolibrary.org/obo/UBERON_0001621	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0081400
+http://purl.obolibrary.org/obo/UBERON_0001982	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0041236
+http://purl.obolibrary.org/obo/UBERON_0001716	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0041237
+http://purl.obolibrary.org/obo/UBERON_0001446	http://purl.obolibrary.org/obo/PATO_0001592	http://purl.obolibrary.org/obo/UPHENO_0041238
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0001499	http://purl.obolibrary.org/obo/UPHENO_0042509
+http://purl.obolibrary.org/obo/UBERON_0002137	http://purl.obolibrary.org/obo/PATO_0002281	http://purl.obolibrary.org/obo/UPHENO_0041240
+http://purl.obolibrary.org/obo/GO_0036126	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0000981	http://purl.obolibrary.org/obo/PATO_0001883	http://purl.obolibrary.org/obo/UPHENO_0041241
+http://purl.obolibrary.org/obo/UBERON_0001456	http://purl.obolibrary.org/obo/PATO_0001786	http://purl.obolibrary.org/obo/UPHENO_0041242
+http://purl.obolibrary.org/obo/UBERON_0008200	http://purl.obolibrary.org/obo/PATO_0000411	http://purl.obolibrary.org/obo/UPHENO_0041243
+http://purl.obolibrary.org/obo/GO_0061827	http://purl.obolibrary.org/obo/PATO_0001865	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002146	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0041244
+http://purl.obolibrary.org/obo/UBERON_0002134	http://purl.obolibrary.org/obo/PATO_0002281	http://purl.obolibrary.org/obo/UPHENO_0041245
+http://purl.obolibrary.org/obo/UBERON_0002113	http://purl.obolibrary.org/obo/PATO_0000403	http://purl.obolibrary.org/obo/UPHENO_0041246
+http://purl.obolibrary.org/obo/UBERON_0001834	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0041247
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0000967	http://purl.obolibrary.org/obo/UPHENO_0041248
+http://purl.obolibrary.org/obo/UBERON_0000056	http://purl.obolibrary.org/obo/PATO_0000403	http://purl.obolibrary.org/obo/UPHENO_0041249
+http://purl.obolibrary.org/obo/UBERON_0006333	http://purl.obolibrary.org/obo/PATO_0000944	http://purl.obolibrary.org/obo/UPHENO_0041250
+http://purl.obolibrary.org/obo/UBERON_0001693	http://purl.obolibrary.org/obo/PATO_0001786	http://purl.obolibrary.org/obo/UPHENO_0041251
diff --git a/src/curation/upheno-fillers/mp/abnormalShapeOfPhysicalEntity.tsv b/src/curation/upheno-fillers/mp/abnormalShapeOfPhysicalEntity.tsv
new file mode 100644
index 00000000..23aecf80
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormalShapeOfPhysicalEntity.tsv
@@ -0,0 +1,19 @@
+entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0000033	http://purl.obolibrary.org/obo/UPHENO_0005980
+http://purl.obolibrary.org/obo/UBERON_0000165	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0005739	http://purl.obolibrary.org/obo/UPHENO_0005993
+http://purl.obolibrary.org/obo/UBERON_0001771	http://purl.obolibrary.org/obo/UPHENO_0005981
+http://purl.obolibrary.org/obo/UBERON_0008200	http://purl.obolibrary.org/obo/UPHENO_0005982
+http://purl.obolibrary.org/obo/BFO_0000002	http://purl.obolibrary.org/obo/UPHENO_0080300
+http://purl.obolibrary.org/obo/UBERON_0001456	http://purl.obolibrary.org/obo/UPHENO_0005983
+http://purl.obolibrary.org/obo/UBERON_0001697	http://purl.obolibrary.org/obo/UPHENO_0005984
+http://purl.obolibrary.org/obo/UBERON_0002412	http://purl.obolibrary.org/obo/UPHENO_0084420
+http://purl.obolibrary.org/obo/UBERON_0002082	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002081	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000233	http://purl.obolibrary.org/obo/UPHENO_0005985
+http://purl.obolibrary.org/obo/UBERON_0001691	http://purl.obolibrary.org/obo/UPHENO_0005986
+http://purl.obolibrary.org/obo/CL_0000232	http://purl.obolibrary.org/obo/UPHENO_0005987
+http://purl.obolibrary.org/obo/UBERON_0003252	http://purl.obolibrary.org/obo/UPHENO_0005988
+http://purl.obolibrary.org/obo/UBERON_0002329	http://purl.obolibrary.org/obo/UPHENO_0005990
+http://purl.obolibrary.org/obo/UBERON_0001833	http://purl.obolibrary.org/obo/UPHENO_0005991
+http://purl.obolibrary.org/obo/UBERON_0000948	http://purl.obolibrary.org/obo/UPHENO_0005992
diff --git a/src/curation/upheno-fillers/mp/abnormalSizeOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/mp/abnormalSizeOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..3ad24dff
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormalSizeOfAnatomicalEntity.tsv
@@ -0,0 +1,86 @@
+entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0000033	http://purl.obolibrary.org/obo/UPHENO_0075148
+http://purl.obolibrary.org/obo/UBERON_0000473	http://purl.obolibrary.org/obo/UPHENO_0075149
+http://purl.obolibrary.org/obo/GO_0097226	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002336	http://purl.obolibrary.org/obo/UPHENO_0075150
+http://purl.obolibrary.org/obo/UBERON_0000995	http://purl.obolibrary.org/obo/UPHENO_0075151
+http://purl.obolibrary.org/obo/UBERON_0000992	http://purl.obolibrary.org/obo/UPHENO_0075152
+http://purl.obolibrary.org/obo/UBERON_0002411	http://purl.obolibrary.org/obo/UPHENO_0075153
+http://purl.obolibrary.org/obo/UBERON_0002054	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002098	http://purl.obolibrary.org/obo/UPHENO_0075154
+http://purl.obolibrary.org/obo/CL_0000232	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002370	http://purl.obolibrary.org/obo/UPHENO_0075155
+http://purl.obolibrary.org/obo/GO_0042470	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0000988	http://purl.obolibrary.org/obo/UPHENO_0075156
+http://purl.obolibrary.org/obo/UBERON_0002329	http://purl.obolibrary.org/obo/UPHENO_0075157
+http://purl.obolibrary.org/obo/UBERON_0002208	http://purl.obolibrary.org/obo/UPHENO_0075158
+http://purl.obolibrary.org/obo/UBERON_0000468	http://purl.obolibrary.org/obo/UPHENO_0075159
+http://purl.obolibrary.org/obo/UBERON_0000029	http://purl.obolibrary.org/obo/UPHENO_0075161
+http://purl.obolibrary.org/obo/UBERON_0000948	http://purl.obolibrary.org/obo/UPHENO_0075162
+http://purl.obolibrary.org/obo/UBERON_0001211	http://purl.obolibrary.org/obo/UPHENO_0075163
+http://purl.obolibrary.org/obo/UBERON_0002421	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0000165	http://purl.obolibrary.org/obo/UPHENO_0075216
+http://purl.obolibrary.org/obo/UBERON_0001134	http://purl.obolibrary.org/obo/UPHENO_0075164
+http://purl.obolibrary.org/obo/UBERON_0008200	http://purl.obolibrary.org/obo/UPHENO_0075165
+http://purl.obolibrary.org/obo/UBERON_0001891	http://purl.obolibrary.org/obo/UPHENO_0075166
+http://purl.obolibrary.org/obo/UBERON_0001890	http://purl.obolibrary.org/obo/UPHENO_0075167
+http://purl.obolibrary.org/obo/UBERON_0000323	http://purl.obolibrary.org/obo/UPHENO_0075168
+http://purl.obolibrary.org/obo/UBERON_0002106	http://purl.obolibrary.org/obo/UPHENO_0075169
+http://purl.obolibrary.org/obo/UBERON_0001897	http://purl.obolibrary.org/obo/UPHENO_0075170
+http://purl.obolibrary.org/obo/UBERON_0001456	http://purl.obolibrary.org/obo/UPHENO_0075171
+http://purl.obolibrary.org/obo/UBERON_0002028	http://purl.obolibrary.org/obo/UPHENO_0075172
+http://purl.obolibrary.org/obo/UBERON_0001697	http://purl.obolibrary.org/obo/UPHENO_0075173
+http://purl.obolibrary.org/obo/UBERON_0000002	http://purl.obolibrary.org/obo/UPHENO_0075174
+http://purl.obolibrary.org/obo/UBERON_0004086	http://purl.obolibrary.org/obo/UPHENO_0075175
+http://purl.obolibrary.org/obo/CL_0000188	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0001750	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0000998	http://purl.obolibrary.org/obo/UPHENO_0075176
+http://purl.obolibrary.org/obo/UBERON_0004714	http://purl.obolibrary.org/obo/UPHENO_0075177
+http://purl.obolibrary.org/obo/UBERON_0000955	http://purl.obolibrary.org/obo/UPHENO_0075178
+http://purl.obolibrary.org/obo/UBERON_0001844	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0003946	http://purl.obolibrary.org/obo/UPHENO_0075179
+http://purl.obolibrary.org/obo/UBERON_0000996	http://purl.obolibrary.org/obo/UPHENO_0075180
+http://purl.obolibrary.org/obo/UBERON_0001249	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0000959	http://purl.obolibrary.org/obo/UPHENO_0075181
+http://purl.obolibrary.org/obo/UBERON_0002113	http://purl.obolibrary.org/obo/UPHENO_0075182
+http://purl.obolibrary.org/obo/UBERON_0001783	http://purl.obolibrary.org/obo/UPHENO_0075183
+http://purl.obolibrary.org/obo/UBERON_0001343	http://purl.obolibrary.org/obo/UPHENO_0075184
+http://purl.obolibrary.org/obo/UBERON_0001264	http://purl.obolibrary.org/obo/UPHENO_0075185
+http://purl.obolibrary.org/obo/UBERON_0022421	http://purl.obolibrary.org/obo/UPHENO_0075186
+http://purl.obolibrary.org/obo/UBERON_0002110	http://purl.obolibrary.org/obo/UPHENO_0075187
+http://purl.obolibrary.org/obo/UBERON_0009024	http://purl.obolibrary.org/obo/UPHENO_0075188
+http://purl.obolibrary.org/obo/UBERON_0003128	http://purl.obolibrary.org/obo/UPHENO_0075189
+http://purl.obolibrary.org/obo/UBERON_0001301	http://purl.obolibrary.org/obo/UPHENO_0075190
+http://purl.obolibrary.org/obo/UBERON_0002038	http://purl.obolibrary.org/obo/UPHENO_0075191
+http://purl.obolibrary.org/obo/UBERON_0002191	http://purl.obolibrary.org/obo/UPHENO_0075192
+http://purl.obolibrary.org/obo/UBERON_0002153	http://purl.obolibrary.org/obo/UPHENO_0075193
+http://purl.obolibrary.org/obo/UBERON_0000052	http://purl.obolibrary.org/obo/UPHENO_0075194
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0075195
+http://purl.obolibrary.org/obo/UBERON_0002470	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002151	http://purl.obolibrary.org/obo/UPHENO_0075196
+http://purl.obolibrary.org/obo/UBERON_0001819	http://purl.obolibrary.org/obo/UPHENO_0075198
+http://purl.obolibrary.org/obo/UBERON_0016634	http://purl.obolibrary.org/obo/UPHENO_0075199
+http://purl.obolibrary.org/obo/UBERON_0000922	http://purl.obolibrary.org/obo/UPHENO_0075200
+http://purl.obolibrary.org/obo/UBERON_0005619	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0000006	http://purl.obolibrary.org/obo/UPHENO_0075201
+http://purl.obolibrary.org/obo/UBERON_0000964	http://purl.obolibrary.org/obo/UPHENO_0075222
+http://purl.obolibrary.org/obo/UBERON_0002107	http://purl.obolibrary.org/obo/UPHENO_0075202
+http://purl.obolibrary.org/obo/UBERON_0000007	http://purl.obolibrary.org/obo/UPHENO_0075203
+http://purl.obolibrary.org/obo/UBERON_0001935	http://purl.obolibrary.org/obo/UPHENO_0075204
+http://purl.obolibrary.org/obo/UBERON_0001950	http://purl.obolibrary.org/obo/UPHENO_0075205
+http://purl.obolibrary.org/obo/UBERON_0002048	http://purl.obolibrary.org/obo/UPHENO_0075206
+http://purl.obolibrary.org/obo/UBERON_0002367	http://purl.obolibrary.org/obo/UPHENO_0075207
+http://purl.obolibrary.org/obo/UBERON_0002082	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002081	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002080	http://purl.obolibrary.org/obo/UPHENO_0075208
+http://purl.obolibrary.org/obo/UBERON_0006086	http://purl.obolibrary.org/obo/UPHENO_0075209
+http://purl.obolibrary.org/obo/CL_0000121	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0004021	http://purl.obolibrary.org/obo/UPHENO_0075210
+http://purl.obolibrary.org/obo/UBERON_0004187	http://purl.obolibrary.org/obo/UPHENO_0075211
+http://purl.obolibrary.org/obo/UBERON_0002084	http://purl.obolibrary.org/obo/UPHENO_0075212
+http://purl.obolibrary.org/obo/CL_0000448	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000449	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000127	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0000019	http://purl.obolibrary.org/obo/UPHENO_0075213
+http://purl.obolibrary.org/obo/UBERON_0003889	http://purl.obolibrary.org/obo/UPHENO_0075214
+http://purl.obolibrary.org/obo/UBERON_0001987	http://purl.obolibrary.org/obo/UPHENO_0075215
diff --git a/src/curation/upheno-fillers/mp/abnormalSizeOfCellularComponent.tsv b/src/curation/upheno-fillers/mp/abnormalSizeOfCellularComponent.tsv
new file mode 100644
index 00000000..f797c069
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormalSizeOfCellularComponent.tsv
@@ -0,0 +1,5 @@
+entity	defined_class
+http://purl.obolibrary.org/obo/GO_0097226	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0042470	http://purl.obolibrary.org/obo/UPHENO_0080625
+http://purl.obolibrary.org/obo/GO_0005575	http://purl.obolibrary.org/obo/UPHENO_0080626
+http://purl.obolibrary.org/obo/GO_0001750	http://purl.obolibrary.org/obo/UPHENO_0080627
diff --git a/src/curation/upheno-fillers/mp/abnormalSpatialPatternOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/mp/abnormalSpatialPatternOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..62259dae
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormalSpatialPatternOfAnatomicalEntity.tsv
@@ -0,0 +1,9 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0080369
+http://purl.obolibrary.org/obo/UBERON_0002073	http://purl.obolibrary.org/obo/UPHENO_0080370
+http://purl.obolibrary.org/obo/CL_0000188	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000059	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001911	http://purl.obolibrary.org/obo/UPHENO_0080371
+http://purl.obolibrary.org/obo/UBERON_0001982	http://purl.obolibrary.org/obo/UPHENO_0080372
+http://purl.obolibrary.org/obo/UBERON_0003501	http://purl.obolibrary.org/obo/UPHENO_0080373
+http://purl.obolibrary.org/obo/UBERON_0001013	http://purl.obolibrary.org/obo/UPHENO_0080374
diff --git a/src/curation/upheno-fillers/mp/abnormalThicknessOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/mp/abnormalThicknessOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..98c6abfe
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormalThicknessOfAnatomicalEntity.tsv
@@ -0,0 +1,17 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002483	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0036126	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002094	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0005777	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0004367	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001242	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0008883	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001791	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001772	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0004784	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001789	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0000964	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001439	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0036286	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0036285	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/mp/abnormalWeightOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/mp/abnormalWeightOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..44aab9cf
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormalWeightOfAnatomicalEntity.tsv
@@ -0,0 +1,45 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0002084	http://purl.obolibrary.org/obo/UPHENO_0010800
+http://purl.obolibrary.org/obo/CL_0000000	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0010412	http://purl.obolibrary.org/obo/UPHENO_0080344
+http://purl.obolibrary.org/obo/UBERON_0002483	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002081	http://purl.obolibrary.org/obo/UPHENO_0010803
+http://purl.obolibrary.org/obo/UBERON_0002080	http://purl.obolibrary.org/obo/UPHENO_0010805
+http://purl.obolibrary.org/obo/CL_0000169	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002048	http://purl.obolibrary.org/obo/UPHENO_0010757
+http://purl.obolibrary.org/obo/UBERON_0001630	http://purl.obolibrary.org/obo/UPHENO_0010756
+http://purl.obolibrary.org/obo/UBERON_0002367	http://purl.obolibrary.org/obo/UPHENO_0010809
+http://purl.obolibrary.org/obo/UBERON_0001377	http://purl.obolibrary.org/obo/UPHENO_0010843
+http://purl.obolibrary.org/obo/UBERON_0002106	http://purl.obolibrary.org/obo/UPHENO_0010844
+http://purl.obolibrary.org/obo/UBERON_0002369	http://purl.obolibrary.org/obo/UPHENO_0010810
+http://purl.obolibrary.org/obo/UBERON_0001153	http://purl.obolibrary.org/obo/UPHENO_0080345
+http://purl.obolibrary.org/obo/UBERON_0001134	http://purl.obolibrary.org/obo/UPHENO_0010845
+http://purl.obolibrary.org/obo/UBERON_0001255	http://purl.obolibrary.org/obo/UPHENO_0010846
+http://purl.obolibrary.org/obo/UBERON_0001987	http://purl.obolibrary.org/obo/UPHENO_0010762
+http://purl.obolibrary.org/obo/UBERON_0000996	http://purl.obolibrary.org/obo/UPHENO_0010779
+http://purl.obolibrary.org/obo/UBERON_0001348	http://purl.obolibrary.org/obo/UPHENO_0080346
+http://purl.obolibrary.org/obo/UBERON_0003889	http://purl.obolibrary.org/obo/UPHENO_0080347
+http://purl.obolibrary.org/obo/UBERON_0000998	http://purl.obolibrary.org/obo/UPHENO_0010780
+http://purl.obolibrary.org/obo/UBERON_0000955	http://purl.obolibrary.org/obo/UPHENO_0010849
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0010763
+http://purl.obolibrary.org/obo/UBERON_0002370	http://purl.obolibrary.org/obo/UPHENO_0010783
+http://purl.obolibrary.org/obo/UBERON_0001301	http://purl.obolibrary.org/obo/UPHENO_0010819
+http://purl.obolibrary.org/obo/UBERON_0000992	http://purl.obolibrary.org/obo/UPHENO_0010787
+http://purl.obolibrary.org/obo/UBERON_0001389	http://purl.obolibrary.org/obo/UPHENO_0010820
+http://purl.obolibrary.org/obo/UBERON_0001388	http://purl.obolibrary.org/obo/UPHENO_0010822
+http://purl.obolibrary.org/obo/UBERON_0001347	http://purl.obolibrary.org/obo/UPHENO_0080348
+http://purl.obolibrary.org/obo/UBERON_0000995	http://purl.obolibrary.org/obo/UPHENO_0010789
+http://purl.obolibrary.org/obo/UBERON_0002078	http://purl.obolibrary.org/obo/UPHENO_0010823
+http://purl.obolibrary.org/obo/UBERON_0001264	http://purl.obolibrary.org/obo/UPHENO_0080349
+http://purl.obolibrary.org/obo/UBERON_0001385	http://purl.obolibrary.org/obo/UPHENO_0010824
+http://purl.obolibrary.org/obo/CL_0000171	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002113	http://purl.obolibrary.org/obo/UPHENO_0010826
+http://purl.obolibrary.org/obo/UBERON_0000473	http://purl.obolibrary.org/obo/UPHENO_0010792
+http://purl.obolibrary.org/obo/UBERON_0001386	http://purl.obolibrary.org/obo/UPHENO_0010827
+http://purl.obolibrary.org/obo/UBERON_0002079	http://purl.obolibrary.org/obo/UPHENO_0010829
+http://purl.obolibrary.org/obo/UBERON_0000947	http://purl.obolibrary.org/obo/UPHENO_0010857
+http://purl.obolibrary.org/obo/UBERON_0000948	http://purl.obolibrary.org/obo/UPHENO_0010859
+http://purl.obolibrary.org/obo/UBERON_0000468	http://purl.obolibrary.org/obo/UPHENO_0010795
+http://purl.obolibrary.org/obo/UBERON_0002107	http://purl.obolibrary.org/obo/UPHENO_0010830
+http://purl.obolibrary.org/obo/UBERON_0000007	http://purl.obolibrary.org/obo/UPHENO_0010767
+http://purl.obolibrary.org/obo/UBERON_0001439	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/mp/abnormallyArchedAnatomicalEntity.tsv b/src/curation/upheno-fillers/mp/abnormallyArchedAnatomicalEntity.tsv
new file mode 100644
index 00000000..5b0c0e57
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormallyArchedAnatomicalEntity.tsv
@@ -0,0 +1,3 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001716	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/mp/abnormallyArrestedBiologicalProcess.tsv b/src/curation/upheno-fillers/mp/abnormallyArrestedBiologicalProcess.tsv
new file mode 100644
index 00000000..3a061a33
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormallyArrestedBiologicalProcess.tsv
@@ -0,0 +1,12 @@
+biological_process	defined_class
+http://purl.obolibrary.org/obo/NBO_0000401	http://purl.obolibrary.org/obo/UPHENO_0080551
+http://purl.obolibrary.org/obo/GO_0007140	http://purl.obolibrary.org/obo/UPHENO_0018630
+http://purl.obolibrary.org/obo/GO_0007283	http://purl.obolibrary.org/obo/UPHENO_0018631
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UPHENO_0018635
+http://purl.obolibrary.org/obo/GO_0007286	http://purl.obolibrary.org/obo/UPHENO_0018614
+http://purl.obolibrary.org/obo/GO_0001503	http://purl.obolibrary.org/obo/UPHENO_0019045
+http://purl.obolibrary.org/obo/GO_0001957	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/NBO_0000013	http://purl.obolibrary.org/obo/UPHENO_0084427
+http://purl.obolibrary.org/obo/GO_0001958	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0042476	http://purl.obolibrary.org/obo/UPHENO_0018615
+http://purl.obolibrary.org/obo/GO_0060073	http://purl.obolibrary.org/obo/UPHENO_0084428
diff --git a/src/curation/upheno-fillers/mp/abnormallyArrestedBiologicalProcessInLocation.tsv b/src/curation/upheno-fillers/mp/abnormallyArrestedBiologicalProcessInLocation.tsv
new file mode 100644
index 00000000..8ef445bf
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormallyArrestedBiologicalProcessInLocation.tsv
@@ -0,0 +1,3 @@
+biological_process	location	defined_class
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0000975	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0001958	http://purl.obolibrary.org/obo/UBERON_0000975	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/mp/abnormallyAsymmetricalAnatomicalEntity.tsv b/src/curation/upheno-fillers/mp/abnormallyAsymmetricalAnatomicalEntity.tsv
new file mode 100644
index 00000000..4a2de18e
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormallyAsymmetricalAnatomicalEntity.tsv
@@ -0,0 +1,9 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0084729
+http://purl.obolibrary.org/obo/UBERON_0006333	http://purl.obolibrary.org/obo/UPHENO_0084730
+http://purl.obolibrary.org/obo/UBERON_0001998	http://purl.obolibrary.org/obo/UPHENO_0084731
+http://purl.obolibrary.org/obo/UBERON_0002292	http://purl.obolibrary.org/obo/UPHENO_0084732
+http://purl.obolibrary.org/obo/UBERON_0001697	http://purl.obolibrary.org/obo/UPHENO_0084733
+http://purl.obolibrary.org/obo/UBERON_0001456	http://purl.obolibrary.org/obo/UPHENO_0084734
+http://purl.obolibrary.org/obo/UBERON_0002001	http://purl.obolibrary.org/obo/UPHENO_0084735
+http://purl.obolibrary.org/obo/UBERON_0000033	http://purl.obolibrary.org/obo/UPHENO_0084736
diff --git a/src/curation/upheno-fillers/mp/abnormallyBentAnatomicalEntity.tsv b/src/curation/upheno-fillers/mp/abnormallyBentAnatomicalEntity.tsv
new file mode 100644
index 00000000..74c1b3ce
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormallyBentAnatomicalEntity.tsv
@@ -0,0 +1,4 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0074399
+http://purl.obolibrary.org/obo/UBERON_0003606	http://purl.obolibrary.org/obo/UPHENO_0074413
+http://purl.obolibrary.org/obo/UBERON_0002544	http://purl.obolibrary.org/obo/UPHENO_0074406
diff --git a/src/curation/upheno-fillers/mp/abnormallyClosedAnatomicalEntity.tsv b/src/curation/upheno-fillers/mp/abnormallyClosedAnatomicalEntity.tsv
new file mode 100644
index 00000000..7f16adfd
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormallyClosedAnatomicalEntity.tsv
@@ -0,0 +1,3 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0074228
+http://purl.obolibrary.org/obo/UBERON_0000019	http://purl.obolibrary.org/obo/UPHENO_0074244
diff --git a/src/curation/upheno-fillers/mp/abnormallyCurledAnatomicalEntity.tsv b/src/curation/upheno-fillers/mp/abnormallyCurledAnatomicalEntity.tsv
new file mode 100644
index 00000000..846b44f6
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormallyCurledAnatomicalEntity.tsv
@@ -0,0 +1,4 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0011933	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0007812	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/mp/abnormallyCurvedAnatomicalEntityByOrientation.tsv b/src/curation/upheno-fillers/mp/abnormallyCurvedAnatomicalEntityByOrientation.tsv
new file mode 100644
index 00000000..b82c1976
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormallyCurvedAnatomicalEntityByOrientation.tsv
@@ -0,0 +1,42 @@
+anatomical_entity	orientation	defined_class
+http://purl.obolibrary.org/obo/UBERON_0000979	http://purl.obolibrary.org/obo/PATO_0001592	http://purl.obolibrary.org/obo/UPHENO_0031090
+http://purl.obolibrary.org/obo/UBERON_0000976	http://purl.obolibrary.org/obo/PATO_0001592	http://purl.obolibrary.org/obo/UPHENO_0031093
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0000406	http://purl.obolibrary.org/obo/UPHENO_0031193
+http://purl.obolibrary.org/obo/UBERON_0001446	http://purl.obolibrary.org/obo/PATO_0001592	http://purl.obolibrary.org/obo/UPHENO_0031195
+http://purl.obolibrary.org/obo/UBERON_0001424	http://purl.obolibrary.org/obo/PATO_0001592	http://purl.obolibrary.org/obo/UPHENO_0031149
+http://purl.obolibrary.org/obo/UBERON_0001423	http://purl.obolibrary.org/obo/PATO_0001592	http://purl.obolibrary.org/obo/UPHENO_0031151
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0002031	http://purl.obolibrary.org/obo/UPHENO_0031152
+http://purl.obolibrary.org/obo/UBERON_0006333	http://purl.obolibrary.org/obo/PATO_0002031	http://purl.obolibrary.org/obo/UPHENO_0031103
+http://purl.obolibrary.org/obo/UBERON_0001446	http://purl.obolibrary.org/obo/PATO_0000406	http://purl.obolibrary.org/obo/UPHENO_0031154
+http://purl.obolibrary.org/obo/UBERON_0000976	http://purl.obolibrary.org/obo/PATO_0000406	http://purl.obolibrary.org/obo/UPHENO_0031238
+http://purl.obolibrary.org/obo/UBERON_0001424	http://purl.obolibrary.org/obo/PATO_0000406	http://purl.obolibrary.org/obo/UPHENO_0031105
+http://purl.obolibrary.org/obo/UBERON_0000964	http://purl.obolibrary.org/obo/PATO_0001848	http://purl.obolibrary.org/obo/UPHENO_0031199
+http://purl.obolibrary.org/obo/UBERON_0000979	http://purl.obolibrary.org/obo/PATO_0000406	http://purl.obolibrary.org/obo/UPHENO_0031245
+http://purl.obolibrary.org/obo/UBERON_0002544	http://purl.obolibrary.org/obo/PATO_0001649	http://purl.obolibrary.org/obo/UPHENO_0031162
+http://purl.obolibrary.org/obo/UBERON_0003128	http://purl.obolibrary.org/obo/PATO_0000406	http://purl.obolibrary.org/obo/UPHENO_0031205
+http://purl.obolibrary.org/obo/UBERON_0006333	http://purl.obolibrary.org/obo/PATO_0000406	http://purl.obolibrary.org/obo/UPHENO_0031165
+http://purl.obolibrary.org/obo/UBERON_0001423	http://purl.obolibrary.org/obo/PATO_0000406	http://purl.obolibrary.org/obo/UPHENO_0031115
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0001848	http://purl.obolibrary.org/obo/UPHENO_0031170
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0001649	http://purl.obolibrary.org/obo/UPHENO_0031253
+http://purl.obolibrary.org/obo/UBERON_0000981	http://purl.obolibrary.org/obo/PATO_0001592	http://purl.obolibrary.org/obo/UPHENO_0031177
+http://purl.obolibrary.org/obo/UBERON_0010513	http://purl.obolibrary.org/obo/PATO_0000406	http://purl.obolibrary.org/obo/UPHENO_0031208
+http://purl.obolibrary.org/obo/UBERON_0002228	http://purl.obolibrary.org/obo/PATO_0001785	http://purl.obolibrary.org/obo/UPHENO_0031209
+http://purl.obolibrary.org/obo/UBERON_0010512	http://purl.obolibrary.org/obo/PATO_0000406	http://purl.obolibrary.org/obo/UPHENO_0031210
+http://purl.obolibrary.org/obo/UBERON_0010511	http://purl.obolibrary.org/obo/PATO_0000406	http://purl.obolibrary.org/obo/UPHENO_0031211
+http://purl.obolibrary.org/obo/UBERON_0001037	http://purl.obolibrary.org/obo/PATO_0001592	http://purl.obolibrary.org/obo/UPHENO_0031181
+http://purl.obolibrary.org/obo/UBERON_0010510	http://purl.obolibrary.org/obo/PATO_0000406	http://purl.obolibrary.org/obo/UPHENO_0031263
+http://purl.obolibrary.org/obo/UBERON_0010513	http://purl.obolibrary.org/obo/PATO_0001592	http://purl.obolibrary.org/obo/UPHENO_0031265
+http://purl.obolibrary.org/obo/UBERON_0000964	http://purl.obolibrary.org/obo/PATO_0000406	http://purl.obolibrary.org/obo/UPHENO_0031129
+http://purl.obolibrary.org/obo/UBERON_0002228	http://purl.obolibrary.org/obo/PATO_0000406	http://purl.obolibrary.org/obo/UPHENO_0031130
+http://purl.obolibrary.org/obo/UBERON_0003128	http://purl.obolibrary.org/obo/PATO_0001789	http://purl.obolibrary.org/obo/UPHENO_0031132
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0001592	http://purl.obolibrary.org/obo/UPHENO_0031268
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0001593	http://purl.obolibrary.org/obo/UPHENO_0031269
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0001785	http://purl.obolibrary.org/obo/UPHENO_0031135
+http://purl.obolibrary.org/obo/UBERON_0000981	http://purl.obolibrary.org/obo/PATO_0000406	http://purl.obolibrary.org/obo/UPHENO_0031137
+http://purl.obolibrary.org/obo/UBERON_0002544	http://purl.obolibrary.org/obo/PATO_0000406	http://purl.obolibrary.org/obo/UPHENO_0031188
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0001789	http://purl.obolibrary.org/obo/UPHENO_0031139
+http://purl.obolibrary.org/obo/UBERON_0010510	http://purl.obolibrary.org/obo/PATO_0001592	http://purl.obolibrary.org/obo/UPHENO_0031140
+http://purl.obolibrary.org/obo/UBERON_0001037	http://purl.obolibrary.org/obo/PATO_0000406	http://purl.obolibrary.org/obo/UPHENO_0031138
+http://purl.obolibrary.org/obo/UBERON_0010513	http://purl.obolibrary.org/obo/PATO_0001593	http://purl.obolibrary.org/obo/UPHENO_0031272
+http://purl.obolibrary.org/obo/UBERON_0010512	http://purl.obolibrary.org/obo/PATO_0001592	http://purl.obolibrary.org/obo/UPHENO_0031273
+http://purl.obolibrary.org/obo/UBERON_0010511	http://purl.obolibrary.org/obo/PATO_0001592	http://purl.obolibrary.org/obo/UPHENO_0031275
diff --git a/src/curation/upheno-fillers/mp/abnormallyDecreasedCoilingOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/mp/abnormallyDecreasedCoilingOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..0ed976f6
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormallyDecreasedCoilingOfAnatomicalEntity.tsv
@@ -0,0 +1,3 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0079498
+http://purl.obolibrary.org/obo/UBERON_0001844	http://purl.obolibrary.org/obo/UPHENO_0079499
diff --git a/src/curation/upheno-fillers/mp/abnormallyDecreasedFunctionalityOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/mp/abnormallyDecreasedFunctionalityOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..c8ff74e5
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormallyDecreasedFunctionalityOfAnatomicalEntity.tsv
@@ -0,0 +1,9 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0066927
+http://purl.obolibrary.org/obo/UBERON_0001602	http://purl.obolibrary.org/obo/UPHENO_0066920
+http://purl.obolibrary.org/obo/UBERON_0001987	http://purl.obolibrary.org/obo/UPHENO_0066922
+http://purl.obolibrary.org/obo/UBERON_0002107	http://purl.obolibrary.org/obo/UPHENO_0066935
+http://purl.obolibrary.org/obo/UBERON_0001603	http://purl.obolibrary.org/obo/UPHENO_0066924
+http://purl.obolibrary.org/obo/UBERON_0001367	http://purl.obolibrary.org/obo/UPHENO_0066929
+http://purl.obolibrary.org/obo/UBERON_0000120	http://purl.obolibrary.org/obo/UPHENO_0084421
+http://purl.obolibrary.org/obo/UBERON_0002046	http://purl.obolibrary.org/obo/UPHENO_0066918
diff --git a/src/curation/upheno-fillers/mp/abnormallyDecreasedHeightOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/mp/abnormallyDecreasedHeightOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..95d919e7
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormallyDecreasedHeightOfAnatomicalEntity.tsv
@@ -0,0 +1,9 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0080351
+http://purl.obolibrary.org/obo/UBERON_0000468	http://purl.obolibrary.org/obo/UPHENO_0080352
+http://purl.obolibrary.org/obo/UBERON_0001833	http://purl.obolibrary.org/obo/UPHENO_0080353
+http://purl.obolibrary.org/obo/UBERON_0003128	http://purl.obolibrary.org/obo/UPHENO_0080354
+http://purl.obolibrary.org/obo/UBERON_0001213	http://purl.obolibrary.org/obo/UPHENO_0080355
+http://purl.obolibrary.org/obo/UBERON_0008200	http://purl.obolibrary.org/obo/UPHENO_0080356
+http://purl.obolibrary.org/obo/UBERON_0006722	http://purl.obolibrary.org/obo/UPHENO_0080357
+http://purl.obolibrary.org/obo/UBERON_0000056	http://purl.obolibrary.org/obo/UPHENO_0080358
diff --git a/src/curation/upheno-fillers/mp/abnormallyDecreasedLengthOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/mp/abnormallyDecreasedLengthOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..ba798e51
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormallyDecreasedLengthOfAnatomicalEntity.tsv
@@ -0,0 +1,86 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0004660	http://purl.obolibrary.org/obo/UPHENO_0046550
+http://purl.obolibrary.org/obo/UBERON_0003450	http://purl.obolibrary.org/obo/UPHENO_0046551
+http://purl.obolibrary.org/obo/UBERON_0003451	http://purl.obolibrary.org/obo/UPHENO_0046553
+http://purl.obolibrary.org/obo/UBERON_0001273	http://purl.obolibrary.org/obo/UPHENO_0046555
+http://purl.obolibrary.org/obo/UBERON_0001075	http://purl.obolibrary.org/obo/UPHENO_0046500
+http://purl.obolibrary.org/obo/UBERON_0007812	http://purl.obolibrary.org/obo/UPHENO_0046558
+http://purl.obolibrary.org/obo/UBERON_0000981	http://purl.obolibrary.org/obo/UPHENO_0046560
+http://purl.obolibrary.org/obo/UBERON_0001037	http://purl.obolibrary.org/obo/UPHENO_0046559
+http://purl.obolibrary.org/obo/UBERON_0002247	http://purl.obolibrary.org/obo/UPHENO_0046561
+http://purl.obolibrary.org/obo/UBERON_0008340	http://purl.obolibrary.org/obo/UPHENO_0046562
+http://purl.obolibrary.org/obo/UBERON_0001155	http://purl.obolibrary.org/obo/UPHENO_0046566
+http://purl.obolibrary.org/obo/UBERON_0002244	http://purl.obolibrary.org/obo/UPHENO_0046567
+http://purl.obolibrary.org/obo/UBERON_0001705	http://purl.obolibrary.org/obo/UPHENO_0046568
+http://purl.obolibrary.org/obo/UBERON_0000979	http://purl.obolibrary.org/obo/UPHENO_0046569
+http://purl.obolibrary.org/obo/UBERON_0001706	http://purl.obolibrary.org/obo/UPHENO_0046570
+http://purl.obolibrary.org/obo/UBERON_0001228	http://purl.obolibrary.org/obo/UPHENO_0046393
+http://purl.obolibrary.org/obo/UBERON_0000974	http://purl.obolibrary.org/obo/UPHENO_0046571
+http://purl.obolibrary.org/obo/UBERON_0000975	http://purl.obolibrary.org/obo/UPHENO_0046572
+http://purl.obolibrary.org/obo/UBERON_0002517	http://purl.obolibrary.org/obo/UPHENO_0046452
+http://purl.obolibrary.org/obo/UBERON_0000976	http://purl.obolibrary.org/obo/UPHENO_0046573
+http://purl.obolibrary.org/obo/UBERON_0003889	http://purl.obolibrary.org/obo/UPHENO_0046395
+http://purl.obolibrary.org/obo/UBERON_0001702	http://purl.obolibrary.org/obo/UPHENO_0046574
+http://purl.obolibrary.org/obo/CL_0000601	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0010222	http://purl.obolibrary.org/obo/UPHENO_0046504
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0046505
+http://purl.obolibrary.org/obo/UBERON_0002470	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0011933	http://purl.obolibrary.org/obo/UPHENO_0046398
+http://purl.obolibrary.org/obo/UBERON_0003128	http://purl.obolibrary.org/obo/UPHENO_0046508
+http://purl.obolibrary.org/obo/UBERON_0002356	http://purl.obolibrary.org/obo/UPHENO_0046575
+http://purl.obolibrary.org/obo/UBERON_0000059	http://purl.obolibrary.org/obo/UPHENO_0046577
+http://purl.obolibrary.org/obo/UBERON_0000378	http://purl.obolibrary.org/obo/UPHENO_0046401
+http://purl.obolibrary.org/obo/UBERON_0003126	http://purl.obolibrary.org/obo/UPHENO_0046509
+http://purl.obolibrary.org/obo/UBERON_0001424	http://purl.obolibrary.org/obo/UPHENO_0046461
+http://purl.obolibrary.org/obo/UBERON_0001423	http://purl.obolibrary.org/obo/UPHENO_0046462
+http://purl.obolibrary.org/obo/UBERON_0002397	http://purl.obolibrary.org/obo/UPHENO_0046510
+http://purl.obolibrary.org/obo/UBERON_0003960	http://purl.obolibrary.org/obo/UPHENO_0046463
+http://purl.obolibrary.org/obo/UBERON_0000210	http://purl.obolibrary.org/obo/UPHENO_0046464
+http://purl.obolibrary.org/obo/UBERON_0000209	http://purl.obolibrary.org/obo/UPHENO_0046466
+http://purl.obolibrary.org/obo/UBERON_0002108	http://purl.obolibrary.org/obo/UPHENO_0046581
+http://purl.obolibrary.org/obo/UBERON_0002228	http://purl.obolibrary.org/obo/UPHENO_0046582
+http://purl.obolibrary.org/obo/UBERON_0001733	http://purl.obolibrary.org/obo/UPHENO_0046513
+http://purl.obolibrary.org/obo/UBERON_0000160	http://purl.obolibrary.org/obo/UPHENO_0046585
+http://purl.obolibrary.org/obo/UBERON_0001691	http://purl.obolibrary.org/obo/UPHENO_0046631
+http://purl.obolibrary.org/obo/UBERON_0001130	http://purl.obolibrary.org/obo/UPHENO_0046589
+http://purl.obolibrary.org/obo/UBERON_0010512	http://purl.obolibrary.org/obo/UPHENO_0046590
+http://purl.obolibrary.org/obo/UBERON_0002544	http://purl.obolibrary.org/obo/UPHENO_0046411
+http://purl.obolibrary.org/obo/UBERON_0002500	http://purl.obolibrary.org/obo/UPHENO_0046476
+http://purl.obolibrary.org/obo/UBERON_0002103	http://purl.obolibrary.org/obo/UPHENO_0046825
+http://purl.obolibrary.org/obo/UBERON_0001456	http://purl.obolibrary.org/obo/UPHENO_0046413
+http://purl.obolibrary.org/obo/UBERON_0007119	http://purl.obolibrary.org/obo/UPHENO_0046595
+http://purl.obolibrary.org/obo/GO_0001917	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0003677	http://purl.obolibrary.org/obo/UPHENO_0046597
+http://purl.obolibrary.org/obo/UBERON_0001098	http://purl.obolibrary.org/obo/UPHENO_0046477
+http://purl.obolibrary.org/obo/UBERON_0002102	http://purl.obolibrary.org/obo/UPHENO_0046826
+http://purl.obolibrary.org/obo/UBERON_0001695	http://purl.obolibrary.org/obo/UPHENO_0046414
+http://purl.obolibrary.org/obo/UBERON_0002101	http://purl.obolibrary.org/obo/UPHENO_0046600
+http://purl.obolibrary.org/obo/GO_0000781	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001844	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001448	http://purl.obolibrary.org/obo/UPHENO_0046418
+http://purl.obolibrary.org/obo/UBERON_0001689	http://purl.obolibrary.org/obo/UPHENO_0046419
+http://purl.obolibrary.org/obo/GO_0001750	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0013678	http://purl.obolibrary.org/obo/UPHENO_0046423
+http://purl.obolibrary.org/obo/GO_0043197	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0006333	http://purl.obolibrary.org/obo/UPHENO_0046425
+http://purl.obolibrary.org/obo/UBERON_0003462	http://purl.obolibrary.org/obo/UPHENO_0046529
+http://purl.obolibrary.org/obo/UBERON_0002295	http://purl.obolibrary.org/obo/UPHENO_0046488
+http://purl.obolibrary.org/obo/GO_0036126	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002533	http://purl.obolibrary.org/obo/UPHENO_0046429
+http://purl.obolibrary.org/obo/UBERON_0003107	http://purl.obolibrary.org/obo/UPHENO_0046533
+http://purl.obolibrary.org/obo/UBERON_0001446	http://purl.obolibrary.org/obo/UPHENO_0046430
+http://purl.obolibrary.org/obo/UBERON_0002414	http://purl.obolibrary.org/obo/UPHENO_0079220
+http://purl.obolibrary.org/obo/UBERON_0008199	http://purl.obolibrary.org/obo/UPHENO_0046432
+http://purl.obolibrary.org/obo/UBERON_0005402	http://purl.obolibrary.org/obo/UPHENO_0046536
+http://purl.obolibrary.org/obo/UBERON_0002331	http://purl.obolibrary.org/obo/UPHENO_0046604
+http://purl.obolibrary.org/obo/UBERON_0002495	http://purl.obolibrary.org/obo/UPHENO_0046538
+http://purl.obolibrary.org/obo/UBERON_0002374	http://purl.obolibrary.org/obo/UPHENO_0046539
+http://purl.obolibrary.org/obo/UBERON_0001681	http://purl.obolibrary.org/obo/UPHENO_0046435
+http://purl.obolibrary.org/obo/UBERON_0003221	http://purl.obolibrary.org/obo/UPHENO_0046541
+http://purl.obolibrary.org/obo/UBERON_0001684	http://purl.obolibrary.org/obo/UPHENO_0046436
+http://purl.obolibrary.org/obo/UBERON_0001683	http://purl.obolibrary.org/obo/UPHENO_0046437
+http://purl.obolibrary.org/obo/UBERON_0001716	http://purl.obolibrary.org/obo/UPHENO_0046544
+http://purl.obolibrary.org/obo/UBERON_0001838	http://purl.obolibrary.org/obo/UPHENO_0046546
+http://purl.obolibrary.org/obo/UBERON_0000468	http://purl.obolibrary.org/obo/UPHENO_0046440
+http://purl.obolibrary.org/obo/UBERON_0006849	http://purl.obolibrary.org/obo/UPHENO_0046547
+http://purl.obolibrary.org/obo/UBERON_0008828	http://purl.obolibrary.org/obo/UPHENO_0046496
diff --git a/src/curation/upheno-fillers/mp/abnormallyDecreasedLevelOfChemicalEntity.tsv b/src/curation/upheno-fillers/mp/abnormallyDecreasedLevelOfChemicalEntity.tsv
new file mode 100644
index 00000000..1c36ad1a
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormallyDecreasedLevelOfChemicalEntity.tsv
@@ -0,0 +1,73 @@
+chemical_entity	defined_class
+http://purl.obolibrary.org/obo/CHEBI_26125	http://purl.obolibrary.org/obo/UPHENO_0066724
+http://purl.obolibrary.org/obo/CHEBI_24741	http://purl.obolibrary.org/obo/UPHENO_0066725
+http://purl.obolibrary.org/obo/CHEBI_16919	http://purl.obolibrary.org/obo/UPHENO_0066726
+http://purl.obolibrary.org/obo/CHEBI_28300	http://purl.obolibrary.org/obo/UPHENO_0066727
+http://purl.obolibrary.org/obo/PR_000007785	http://purl.obolibrary.org/obo/UPHENO_0066728
+http://purl.obolibrary.org/obo/CHEBI_15428	http://purl.obolibrary.org/obo/UPHENO_0066729
+http://purl.obolibrary.org/obo/CHEBI_18132	http://purl.obolibrary.org/obo/UPHENO_0084471
+http://purl.obolibrary.org/obo/CHEBI_16393	http://purl.obolibrary.org/obo/UPHENO_0066730
+http://purl.obolibrary.org/obo/CHEBI_26607	http://purl.obolibrary.org/obo/UPHENO_0066731
+http://purl.obolibrary.org/obo/CHEBI_8337	http://purl.obolibrary.org/obo/UPHENO_0066732
+http://purl.obolibrary.org/obo/CHEBI_30660	http://purl.obolibrary.org/obo/UPHENO_0066733
+http://purl.obolibrary.org/obo/CHEBI_18059	http://purl.obolibrary.org/obo/UPHENO_0066793
+http://purl.obolibrary.org/obo/CHEBI_18257	http://purl.obolibrary.org/obo/UPHENO_0066734
+http://purl.obolibrary.org/obo/CHEBI_17761	http://purl.obolibrary.org/obo/UPHENO_0066735
+http://purl.obolibrary.org/obo/CHEBI_30860	http://purl.obolibrary.org/obo/UPHENO_0066736
+http://purl.obolibrary.org/obo/CHEBI_16113	http://purl.obolibrary.org/obo/UPHENO_0066737
+http://purl.obolibrary.org/obo/CHEBI_18258	http://purl.obolibrary.org/obo/UPHENO_0066738
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+http://purl.obolibrary.org/obo/PR_000013246	http://purl.obolibrary.org/obo/UPHENO_0066768
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+http://purl.obolibrary.org/obo/CHEBI_81567	http://purl.obolibrary.org/obo/UPHENO_0066772
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+http://purl.obolibrary.org/obo/PR_000003777	http://purl.obolibrary.org/obo/UPHENO_0066777
+http://purl.obolibrary.org/obo/CHEBI_2700	http://purl.obolibrary.org/obo/UPHENO_0084474
+http://purl.obolibrary.org/obo/CHEBI_17855	http://purl.obolibrary.org/obo/UPHENO_0066778
+http://purl.obolibrary.org/obo/CHEBI_36477	http://purl.obolibrary.org/obo/UPHENO_0066779
+http://purl.obolibrary.org/obo/CHEBI_16526	http://purl.obolibrary.org/obo/UPHENO_0066780
+http://purl.obolibrary.org/obo/CHEBI_36313	http://purl.obolibrary.org/obo/UPHENO_0084475
+http://purl.obolibrary.org/obo/CHEBI_29073	http://purl.obolibrary.org/obo/UPHENO_0081712
+http://purl.obolibrary.org/obo/CHEBI_15354	http://purl.obolibrary.org/obo/UPHENO_0084476
+http://purl.obolibrary.org/obo/PR_000016480	http://purl.obolibrary.org/obo/UPHENO_0083855
+http://purl.obolibrary.org/obo/CHEBI_15355	http://purl.obolibrary.org/obo/UPHENO_0083856
diff --git a/src/curation/upheno-fillers/mp/abnormallyDecreasedLevelOfChemicalEntityInLocation.tsv b/src/curation/upheno-fillers/mp/abnormallyDecreasedLevelOfChemicalEntityInLocation.tsv
new file mode 100644
index 00000000..8516ed80
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormallyDecreasedLevelOfChemicalEntityInLocation.tsv
@@ -0,0 +1,192 @@
+chemical_entity	location	defined_class
+http://purl.obolibrary.org/obo/CHEBI_25017	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0034145
+http://purl.obolibrary.org/obo/CHEBI_18248	http://purl.obolibrary.org/obo/UBERON_0000160	http://purl.obolibrary.org/obo/UPHENO_0034146
+http://purl.obolibrary.org/obo/CHEBI_16919	http://purl.obolibrary.org/obo/UBERON_0001088	http://purl.obolibrary.org/obo/UPHENO_0034148
+http://purl.obolibrary.org/obo/CHEBI_24431	http://purl.obolibrary.org/obo/UBERON_0002048	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CHEBI_24431	http://purl.obolibrary.org/obo/UBERON_0001988	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CHEBI_30052	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0034150
+http://purl.obolibrary.org/obo/CHEBI_17026	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0034151
+http://purl.obolibrary.org/obo/PR_000000134	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0034152
+http://purl.obolibrary.org/obo/CHEBI_15422	http://purl.obolibrary.org/obo/CL_0000233	http://purl.obolibrary.org/obo/UPHENO_0076002
+http://purl.obolibrary.org/obo/CHEBI_17996	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0034156
+http://purl.obolibrary.org/obo/CHEBI_17754	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0034157
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+http://purl.obolibrary.org/obo/CHEBI_28694	http://purl.obolibrary.org/obo/UBERON_0002298	http://purl.obolibrary.org/obo/UPHENO_0034164
+http://purl.obolibrary.org/obo/CHEBI_27584	http://purl.obolibrary.org/obo/UBERON_0001088	http://purl.obolibrary.org/obo/UPHENO_0034168
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+http://purl.obolibrary.org/obo/PR_000000017	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0034174
+http://purl.obolibrary.org/obo/CHEBI_35143	http://purl.obolibrary.org/obo/CL_0000595	http://purl.obolibrary.org/obo/UPHENO_0076003
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+http://purl.obolibrary.org/obo/CHEBI_36477	http://purl.obolibrary.org/obo/UBERON_0000955	http://purl.obolibrary.org/obo/UPHENO_0034176
+http://purl.obolibrary.org/obo/CHEBI_17544	http://purl.obolibrary.org/obo/UBERON_0001088	http://purl.obolibrary.org/obo/UPHENO_0034177
+http://purl.obolibrary.org/obo/PR_000008056	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0034178
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+http://purl.obolibrary.org/obo/CHEBI_18085	http://purl.obolibrary.org/obo/UBERON_0001088	http://purl.obolibrary.org/obo/UPHENO_0034184
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+http://purl.obolibrary.org/obo/CHEBI_25107	http://purl.obolibrary.org/obo/UBERON_0001088	http://purl.obolibrary.org/obo/UPHENO_0034281
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+http://purl.obolibrary.org/obo/CHEBI_16336	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0084757
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+http://purl.obolibrary.org/obo/CHEBI_26986	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0034293
+http://purl.obolibrary.org/obo/CHEBI_16330	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0034297
+http://purl.obolibrary.org/obo/CHEBI_28694	http://purl.obolibrary.org/obo/UBERON_0000955	http://purl.obolibrary.org/obo/UPHENO_0034298
+http://purl.obolibrary.org/obo/CHEBI_27363	http://purl.obolibrary.org/obo/UBERON_0000955	http://purl.obolibrary.org/obo/UPHENO_0034299
+http://purl.obolibrary.org/obo/CHEBI_16113	http://purl.obolibrary.org/obo/UBERON_0000955	http://purl.obolibrary.org/obo/UPHENO_0034303
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diff --git a/src/curation/upheno-fillers/mp/abnormallyDecreasedLevelOfChemicalEntityWithRoleInLocation.tsv b/src/curation/upheno-fillers/mp/abnormallyDecreasedLevelOfChemicalEntityWithRoleInLocation.tsv
new file mode 100644
index 00000000..c2947d87
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormallyDecreasedLevelOfChemicalEntityWithRoleInLocation.tsv
@@ -0,0 +1,3 @@
+location	role	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001088	http://purl.obolibrary.org/obo/CHEBI_24621	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001088	http://purl.obolibrary.org/obo/CHEBI_50906	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/mp/abnormallyDecreasedMassDensityOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/mp/abnormallyDecreasedMassDensityOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..4fd5960a
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormallyDecreasedMassDensityOfAnatomicalEntity.tsv
@@ -0,0 +1,3 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0082834
+http://purl.obolibrary.org/obo/UBERON_0001474	http://purl.obolibrary.org/obo/UPHENO_0082835
diff --git a/src/curation/upheno-fillers/mp/abnormallyDecreasedMassOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/mp/abnormallyDecreasedMassOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..e689b90d
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormallyDecreasedMassOfAnatomicalEntity.tsv
@@ -0,0 +1,59 @@
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+http://purl.obolibrary.org/obo/UBERON_0002084	http://purl.obolibrary.org/obo/UPHENO_0082744
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diff --git a/src/curation/upheno-fillers/mp/abnormallyDecreasedMobilityOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/mp/abnormallyDecreasedMobilityOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..c770cffd
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormallyDecreasedMobilityOfAnatomicalEntity.tsv
@@ -0,0 +1,3 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0076671
+http://purl.obolibrary.org/obo/UBERON_0000982	http://purl.obolibrary.org/obo/UPHENO_0076672
diff --git a/src/curation/upheno-fillers/mp/abnormallyDecreasedNumberOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/mp/abnormallyDecreasedNumberOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..961ec3a6
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormallyDecreasedNumberOfAnatomicalEntity.tsv
@@ -0,0 +1,221 @@
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+http://purl.obolibrary.org/obo/CL_0000037	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000038	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002374	http://purl.obolibrary.org/obo/UPHENO_0063775
+http://purl.obolibrary.org/obo/UBERON_0001285	http://purl.obolibrary.org/obo/UPHENO_0063776
+http://purl.obolibrary.org/obo/UBERON_0001959	http://purl.obolibrary.org/obo/UPHENO_0063784
+http://purl.obolibrary.org/obo/CL_0000958	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000959	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0005196	http://purl.obolibrary.org/obo/UPHENO_0063791
+http://purl.obolibrary.org/obo/CL_0000763	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001037	http://purl.obolibrary.org/obo/UPHENO_0063792
+http://purl.obolibrary.org/obo/UBERON_0002485	http://purl.obolibrary.org/obo/UPHENO_0063797
+http://purl.obolibrary.org/obo/CL_0002140	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000084	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001821	http://purl.obolibrary.org/obo/UPHENO_0063806
+http://purl.obolibrary.org/obo/UBERON_0001702	http://purl.obolibrary.org/obo/UPHENO_0063808
+http://purl.obolibrary.org/obo/CL_0000765	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000767	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000097	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000771	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000650	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000893	http://purl.obolibrary.org/obo/UPHENO_0084757
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+http://purl.obolibrary.org/obo/CL_0000775	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000092	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000094	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002113	http://purl.obolibrary.org/obo/UPHENO_0063822
+http://purl.obolibrary.org/obo/UBERON_0002228	http://purl.obolibrary.org/obo/UPHENO_0063827
+http://purl.obolibrary.org/obo/CL_0000897	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0010513	http://purl.obolibrary.org/obo/UPHENO_0063833
+http://purl.obolibrary.org/obo/CL_0000188	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001250	http://purl.obolibrary.org/obo/UPHENO_0063841
+http://purl.obolibrary.org/obo/CL_0002489	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000740	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0002488	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002347	http://purl.obolibrary.org/obo/UPHENO_0063850
+http://purl.obolibrary.org/obo/CL_0002481	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000061	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000182	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000062	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001013	http://purl.obolibrary.org/obo/UPHENO_0063854
+http://purl.obolibrary.org/obo/UBERON_0004883	http://purl.obolibrary.org/obo/UPHENO_0063858
+http://purl.obolibrary.org/obo/UBERON_0001249	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0001750	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000623	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000624	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000503	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000625	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000988	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000746	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0043197	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0002375	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0002495	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0008799	http://purl.obolibrary.org/obo/UPHENO_0063871
+http://purl.obolibrary.org/obo/CL_0002499	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000510	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0002139	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0000035	http://purl.obolibrary.org/obo/UPHENO_0063877
+http://purl.obolibrary.org/obo/UBERON_0000036	http://purl.obolibrary.org/obo/UPHENO_0084437
+http://purl.obolibrary.org/obo/UBERON_0000037	http://purl.obolibrary.org/obo/UPHENO_0063879
+http://purl.obolibrary.org/obo/UBERON_0002336	http://purl.obolibrary.org/obo/UPHENO_0063880
+http://purl.obolibrary.org/obo/UBERON_0002451	http://purl.obolibrary.org/obo/UPHENO_0063882
+http://purl.obolibrary.org/obo/CL_0002370	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0000029	http://purl.obolibrary.org/obo/UPHENO_0063885
+http://purl.obolibrary.org/obo/UBERON_0001911	http://purl.obolibrary.org/obo/UPHENO_0063886
+http://purl.obolibrary.org/obo/UBERON_0002208	http://purl.obolibrary.org/obo/UPHENO_0063887
diff --git a/src/curation/upheno-fillers/mp/abnormallyDecreasedNumberOfAnatomicalEntityInLocation.tsv b/src/curation/upheno-fillers/mp/abnormallyDecreasedNumberOfAnatomicalEntityInLocation.tsv
new file mode 100644
index 00000000..7ee0dee9
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormallyDecreasedNumberOfAnatomicalEntityInLocation.tsv
@@ -0,0 +1,48 @@
+anatomical_entity	location	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/CL_0002368	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0001348	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0001474	http://purl.obolibrary.org/obo/UPHENO_0034969
+http://purl.obolibrary.org/obo/UBERON_0003606	http://purl.obolibrary.org/obo/UBERON_0002101	http://purl.obolibrary.org/obo/UPHENO_0034973
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0002240	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0015813	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000232	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002544	http://purl.obolibrary.org/obo/UBERON_0002102	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002544	http://purl.obolibrary.org/obo/UBERON_0002101	http://purl.obolibrary.org/obo/UPHENO_0035033
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/CL_0000295	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0002113	http://purl.obolibrary.org/obo/UPHENO_0035042
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/CL_0000601	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0032420	http://purl.obolibrary.org/obo/CL_0000609	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/CL_0000609	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0032420	http://purl.obolibrary.org/obo/CL_0000601	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/CL_0002064	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002544	http://purl.obolibrary.org/obo/UBERON_0002103	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0002106	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000598	http://purl.obolibrary.org/obo/UBERON_0000956	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0032420	http://purl.obolibrary.org/obo/CL_0000202	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0005811	http://purl.obolibrary.org/obo/UBERON_0001348	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/CL_0000202	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001232	http://purl.obolibrary.org/obo/UBERON_0002113	http://purl.obolibrary.org/obo/UPHENO_0034992
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0002103	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0031514	http://purl.obolibrary.org/obo/CL_0002368	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0002102	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0002101	http://purl.obolibrary.org/obo/UPHENO_0035060
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0000956	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001013	http://purl.obolibrary.org/obo/UBERON_0000916	http://purl.obolibrary.org/obo/UPHENO_0034994
+http://purl.obolibrary.org/obo/CL_0000100	http://purl.obolibrary.org/obo/UBERON_0002240	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000160	http://purl.obolibrary.org/obo/UBERON_0015813	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000000	http://purl.obolibrary.org/obo/UBERON_0002106	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0004089	http://purl.obolibrary.org/obo/UPHENO_0035067
+http://purl.obolibrary.org/obo/UBERON_0000440	http://purl.obolibrary.org/obo/UBERON_0001474	http://purl.obolibrary.org/obo/UPHENO_0035000
+http://purl.obolibrary.org/obo/GO_0042588	http://purl.obolibrary.org/obo/CL_0002064	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0030141	http://purl.obolibrary.org/obo/CL_0000295	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000598	http://purl.obolibrary.org/obo/UBERON_0001954	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0001954	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/CL_0000589	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001982	http://purl.obolibrary.org/obo/UBERON_0000074	http://purl.obolibrary.org/obo/UPHENO_0035011
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0000916	http://purl.obolibrary.org/obo/UPHENO_0035013
+http://purl.obolibrary.org/obo/CL_0000763	http://purl.obolibrary.org/obo/UBERON_0002371	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0032420	http://purl.obolibrary.org/obo/CL_0000589	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0000074	http://purl.obolibrary.org/obo/UPHENO_0035016
+http://purl.obolibrary.org/obo/UBERON_0011933	http://purl.obolibrary.org/obo/UBERON_0004089	http://purl.obolibrary.org/obo/UPHENO_0035083
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0002371	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/mp/abnormallyDecreasedNumberOfCellularComponent.tsv b/src/curation/upheno-fillers/mp/abnormallyDecreasedNumberOfCellularComponent.tsv
new file mode 100644
index 00000000..4409dfb9
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormallyDecreasedNumberOfCellularComponent.tsv
@@ -0,0 +1,11 @@
+cellular_component	defined_class
+http://purl.obolibrary.org/obo/GO_0043197	http://purl.obolibrary.org/obo/UPHENO_0084205
+http://purl.obolibrary.org/obo/GO_0042827	http://purl.obolibrary.org/obo/UPHENO_0046249
+http://purl.obolibrary.org/obo/GO_0005739	http://purl.obolibrary.org/obo/UPHENO_0046250
+http://purl.obolibrary.org/obo/GO_0097208	http://purl.obolibrary.org/obo/UPHENO_0046251
+http://purl.obolibrary.org/obo/GO_0005575	http://purl.obolibrary.org/obo/UPHENO_0046252
+http://purl.obolibrary.org/obo/GO_0002185	http://purl.obolibrary.org/obo/UPHENO_0046253
+http://purl.obolibrary.org/obo/GO_0031091	http://purl.obolibrary.org/obo/UPHENO_0046254
+http://purl.obolibrary.org/obo/GO_0042613	http://purl.obolibrary.org/obo/UPHENO_0046255
+http://purl.obolibrary.org/obo/GO_0001750	http://purl.obolibrary.org/obo/UPHENO_0046256
+http://purl.obolibrary.org/obo/GO_0042612	http://purl.obolibrary.org/obo/UPHENO_0046257
diff --git a/src/curation/upheno-fillers/mp/abnormallyDecreasedPigmentationOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/mp/abnormallyDecreasedPigmentationOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..710af1c1
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormallyDecreasedPigmentationOfAnatomicalEntity.tsv
@@ -0,0 +1,3 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0018526
+http://purl.obolibrary.org/obo/UBERON_0015484	http://purl.obolibrary.org/obo/UPHENO_0018536
diff --git a/src/curation/upheno-fillers/mp/abnormallyDecreasedPositionOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/mp/abnormallyDecreasedPositionOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..f92caf74
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormallyDecreasedPositionOfAnatomicalEntity.tsv
@@ -0,0 +1,3 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0081783
+http://purl.obolibrary.org/obo/UBERON_0001691	http://purl.obolibrary.org/obo/UPHENO_0081784
diff --git a/src/curation/upheno-fillers/mp/abnormallyDecreasedQualityOfBiologicalProcess.tsv b/src/curation/upheno-fillers/mp/abnormallyDecreasedQualityOfBiologicalProcess.tsv
new file mode 100644
index 00000000..42cd3883
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormallyDecreasedQualityOfBiologicalProcess.tsv
@@ -0,0 +1,14 @@
+biological_process	defined_class
+http://purl.obolibrary.org/obo/NBO_0001987	http://purl.obolibrary.org/obo/UPHENO_0082002
+http://purl.obolibrary.org/obo/GO_0001553	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0030317	http://purl.obolibrary.org/obo/UPHENO_0052749
+http://purl.obolibrary.org/obo/GO_0097421	http://purl.obolibrary.org/obo/UPHENO_0083981
+http://purl.obolibrary.org/obo/GO_0044321	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0007056	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0009566	http://purl.obolibrary.org/obo/UPHENO_0082001
+http://purl.obolibrary.org/obo/GO_0043403	http://purl.obolibrary.org/obo/UPHENO_0082006
+http://purl.obolibrary.org/obo/GO_0040038	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UPHENO_0052178
+http://purl.obolibrary.org/obo/GO_0042628	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0061026	http://purl.obolibrary.org/obo/UPHENO_0052450
+http://purl.obolibrary.org/obo/GO_0099129	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/mp/abnormallyDecreasedQualityOfBiologicalProcessInLocation.tsv b/src/curation/upheno-fillers/mp/abnormallyDecreasedQualityOfBiologicalProcessInLocation.tsv
new file mode 100644
index 00000000..e8b62373
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormallyDecreasedQualityOfBiologicalProcessInLocation.tsv
@@ -0,0 +1,13 @@
+biological_process	location	defined_class
+http://purl.obolibrary.org/obo/GO_0042246	http://purl.obolibrary.org/obo/UBERON_0000160	http://purl.obolibrary.org/obo/UPHENO_0083691
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0000160	http://purl.obolibrary.org/obo/UPHENO_0083694
+http://purl.obolibrary.org/obo/GO_0001503	http://purl.obolibrary.org/obo/UBERON_0006428	http://purl.obolibrary.org/obo/UPHENO_0084469
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0001017	http://purl.obolibrary.org/obo/UPHENO_0083689
+http://purl.obolibrary.org/obo/GO_0042246	http://purl.obolibrary.org/obo/UBERON_0001264	http://purl.obolibrary.org/obo/UPHENO_0083690
+http://purl.obolibrary.org/obo/GO_0042246	http://purl.obolibrary.org/obo/UBERON_0001017	http://purl.obolibrary.org/obo/UPHENO_0083692
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+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0001264	http://purl.obolibrary.org/obo/UPHENO_0083696
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0000010	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/mp/abnormallyDecreasedRateOfBehavior.tsv b/src/curation/upheno-fillers/mp/abnormallyDecreasedRateOfBehavior.tsv
new file mode 100644
index 00000000..f8d6dfaf
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormallyDecreasedRateOfBehavior.tsv
@@ -0,0 +1,40 @@
+behavior_process	defined_class
+http://purl.obolibrary.org/obo/NBO_0000015	http://purl.obolibrary.org/obo/UPHENO_0074358
+http://purl.obolibrary.org/obo/NBO_0000037	http://purl.obolibrary.org/obo/UPHENO_0074359
+http://purl.obolibrary.org/obo/NBO_0000313	http://purl.obolibrary.org/obo/UPHENO_0074360
+http://purl.obolibrary.org/obo/NBO_0000412	http://purl.obolibrary.org/obo/UPHENO_0074362
+http://purl.obolibrary.org/obo/NBO_0000159	http://purl.obolibrary.org/obo/UPHENO_0074363
+http://purl.obolibrary.org/obo/NBO_0000578	http://purl.obolibrary.org/obo/UPHENO_0074365
+http://purl.obolibrary.org/obo/NBO_0000336	http://purl.obolibrary.org/obo/UPHENO_0074364
+http://purl.obolibrary.org/obo/NBO_0000338	http://purl.obolibrary.org/obo/UPHENO_0084424
+http://purl.obolibrary.org/obo/NBO_0000339	http://purl.obolibrary.org/obo/UPHENO_0074367
+http://purl.obolibrary.org/obo/NBO_0000218	http://purl.obolibrary.org/obo/UPHENO_0074368
+http://purl.obolibrary.org/obo/NBO_0000318	http://purl.obolibrary.org/obo/UPHENO_0074369
+http://purl.obolibrary.org/obo/NBO_0001728	http://purl.obolibrary.org/obo/UPHENO_0074370
+http://purl.obolibrary.org/obo/NBO_0002362	http://purl.obolibrary.org/obo/UPHENO_0074371
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+http://purl.obolibrary.org/obo/NBO_0000381	http://purl.obolibrary.org/obo/UPHENO_0080062
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+http://purl.obolibrary.org/obo/NBO_0000223	http://purl.obolibrary.org/obo/UPHENO_0074376
+http://purl.obolibrary.org/obo/NBO_0000103	http://purl.obolibrary.org/obo/UPHENO_0074377
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+http://purl.obolibrary.org/obo/NBO_0000545	http://purl.obolibrary.org/obo/UPHENO_0074380
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+http://purl.obolibrary.org/obo/NBO_0000107	http://purl.obolibrary.org/obo/UPHENO_0074382
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+http://purl.obolibrary.org/obo/NBO_0000449	http://purl.obolibrary.org/obo/UPHENO_0084425
+http://purl.obolibrary.org/obo/NBO_0002234	http://purl.obolibrary.org/obo/UPHENO_0074384
+http://purl.obolibrary.org/obo/NBO_0000091	http://purl.obolibrary.org/obo/UPHENO_0074385
+http://purl.obolibrary.org/obo/NBO_0000092	http://purl.obolibrary.org/obo/UPHENO_0074386
+http://purl.obolibrary.org/obo/NBO_0000391	http://purl.obolibrary.org/obo/UPHENO_0074387
+http://purl.obolibrary.org/obo/NBO_0000371	http://purl.obolibrary.org/obo/UPHENO_0074388
+http://purl.obolibrary.org/obo/NBO_0000097	http://purl.obolibrary.org/obo/UPHENO_0074389
+http://purl.obolibrary.org/obo/NBO_0000131	http://purl.obolibrary.org/obo/UPHENO_0074390
+http://purl.obolibrary.org/obo/NBO_0000110	http://purl.obolibrary.org/obo/UPHENO_0074391
+http://purl.obolibrary.org/obo/NBO_0000013	http://purl.obolibrary.org/obo/UPHENO_0084426
+http://purl.obolibrary.org/obo/NBO_0000332	http://purl.obolibrary.org/obo/UPHENO_0074393
+http://purl.obolibrary.org/obo/NBO_0000211	http://purl.obolibrary.org/obo/UPHENO_0080550
+http://purl.obolibrary.org/obo/NBO_0001763	http://purl.obolibrary.org/obo/UPHENO_0074395
diff --git a/src/curation/upheno-fillers/mp/abnormallyDecreasedRateOfBiologicalProcess.tsv b/src/curation/upheno-fillers/mp/abnormallyDecreasedRateOfBiologicalProcess.tsv
new file mode 100644
index 00000000..ad8bb9ca
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormallyDecreasedRateOfBiologicalProcess.tsv
@@ -0,0 +1,62 @@
+biological_process	defined_class
+http://purl.obolibrary.org/obo/NBO_0000448	http://purl.obolibrary.org/obo/UPHENO_0005411
+http://purl.obolibrary.org/obo/NBO_0000449	http://purl.obolibrary.org/obo/UPHENO_0084418
+http://purl.obolibrary.org/obo/GO_0007341	http://purl.obolibrary.org/obo/UPHENO_0076897
+http://purl.obolibrary.org/obo/NBO_0002234	http://purl.obolibrary.org/obo/UPHENO_0080250
+http://purl.obolibrary.org/obo/NBO_0000091	http://purl.obolibrary.org/obo/UPHENO_0080251
+http://purl.obolibrary.org/obo/NBO_0000092	http://purl.obolibrary.org/obo/UPHENO_0080252
+http://purl.obolibrary.org/obo/GO_0035036	http://purl.obolibrary.org/obo/UPHENO_0076898
+http://purl.obolibrary.org/obo/NBO_0000097	http://purl.obolibrary.org/obo/UPHENO_0080253
+http://purl.obolibrary.org/obo/NBO_0000131	http://purl.obolibrary.org/obo/UPHENO_0080254
+http://purl.obolibrary.org/obo/NBO_0000371	http://purl.obolibrary.org/obo/UPHENO_0005499
+http://purl.obolibrary.org/obo/GO_0030421	http://purl.obolibrary.org/obo/UPHENO_0005579
+http://purl.obolibrary.org/obo/NBO_0000013	http://purl.obolibrary.org/obo/UPHENO_0005500
+http://purl.obolibrary.org/obo/NBO_0000332	http://purl.obolibrary.org/obo/UPHENO_0080255
+http://purl.obolibrary.org/obo/NBO_0000211	http://purl.obolibrary.org/obo/UPHENO_0080256
+http://purl.obolibrary.org/obo/GO_0007339	http://purl.obolibrary.org/obo/UPHENO_0076899
+http://purl.obolibrary.org/obo/NBO_0000037	http://purl.obolibrary.org/obo/UPHENO_0080257
+http://purl.obolibrary.org/obo/GO_0070091	http://purl.obolibrary.org/obo/UPHENO_0005581
+http://purl.obolibrary.org/obo/NBO_0000159	http://purl.obolibrary.org/obo/UPHENO_0005548
+http://purl.obolibrary.org/obo/GO_0001951	http://purl.obolibrary.org/obo/UPHENO_0005503
+http://purl.obolibrary.org/obo/NBO_0000318	http://purl.obolibrary.org/obo/UPHENO_0080258
+http://purl.obolibrary.org/obo/GO_0042060	http://purl.obolibrary.org/obo/UPHENO_0005582
+http://purl.obolibrary.org/obo/GO_0045453	http://purl.obolibrary.org/obo/UPHENO_0005584
+http://purl.obolibrary.org/obo/GO_0003094	http://purl.obolibrary.org/obo/UPHENO_0005549
+http://purl.obolibrary.org/obo/NBO_0001728	http://purl.obolibrary.org/obo/UPHENO_0080259
+http://purl.obolibrary.org/obo/GO_0046541	http://purl.obolibrary.org/obo/UPHENO_0005585
+http://purl.obolibrary.org/obo/NBO_0002065	http://purl.obolibrary.org/obo/UPHENO_0080260
+http://purl.obolibrary.org/obo/GO_0006094	http://purl.obolibrary.org/obo/UPHENO_0005430
+http://purl.obolibrary.org/obo/GO_0040007	http://purl.obolibrary.org/obo/UPHENO_0005431
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UPHENO_0005433
+http://purl.obolibrary.org/obo/NBO_0002021	http://purl.obolibrary.org/obo/UPHENO_0080261
+http://purl.obolibrary.org/obo/NBO_0000545	http://purl.obolibrary.org/obo/UPHENO_0080262
+http://purl.obolibrary.org/obo/NBO_0001679	http://purl.obolibrary.org/obo/UPHENO_0080263
+http://purl.obolibrary.org/obo/NBO_0000103	http://purl.obolibrary.org/obo/UPHENO_0080264
+http://purl.obolibrary.org/obo/GO_0001542	http://purl.obolibrary.org/obo/UPHENO_0084419
+http://purl.obolibrary.org/obo/NBO_0000224	http://purl.obolibrary.org/obo/UPHENO_0080265
+http://purl.obolibrary.org/obo/GO_0050798	http://purl.obolibrary.org/obo/UPHENO_0005557
+http://purl.obolibrary.org/obo/NBO_0000027	http://purl.obolibrary.org/obo/UPHENO_0080266
+http://purl.obolibrary.org/obo/GO_0001541	http://purl.obolibrary.org/obo/UPHENO_0005439
+http://purl.obolibrary.org/obo/NBO_0000107	http://purl.obolibrary.org/obo/UPHENO_0080267
+http://purl.obolibrary.org/obo/GO_0007605	http://purl.obolibrary.org/obo/UPHENO_0005518
+http://purl.obolibrary.org/obo/GO_0007566	http://purl.obolibrary.org/obo/UPHENO_0005605
+http://purl.obolibrary.org/obo/GO_0005980	http://purl.obolibrary.org/obo/UPHENO_0005560
+http://purl.obolibrary.org/obo/GO_0042730	http://purl.obolibrary.org/obo/UPHENO_0005607
+http://purl.obolibrary.org/obo/NBO_0000391	http://purl.obolibrary.org/obo/UPHENO_0080268
+http://purl.obolibrary.org/obo/NBO_0001763	http://purl.obolibrary.org/obo/UPHENO_0080269
+http://purl.obolibrary.org/obo/NBO_0000110	http://purl.obolibrary.org/obo/UPHENO_0080270
+http://purl.obolibrary.org/obo/NBO_0000578	http://purl.obolibrary.org/obo/UPHENO_0080271
+http://purl.obolibrary.org/obo/NBO_0000336	http://purl.obolibrary.org/obo/UPHENO_0080272
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+http://purl.obolibrary.org/obo/NBO_0000338	http://purl.obolibrary.org/obo/UPHENO_0005469
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+http://purl.obolibrary.org/obo/GO_0042640	http://purl.obolibrary.org/obo/UPHENO_0005473
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+http://purl.obolibrary.org/obo/NBO_0000381	http://purl.obolibrary.org/obo/UPHENO_0076900
+http://purl.obolibrary.org/obo/NBO_0000222	http://purl.obolibrary.org/obo/UPHENO_0080278
+http://purl.obolibrary.org/obo/NBO_0000223	http://purl.obolibrary.org/obo/UPHENO_0080279
+http://purl.obolibrary.org/obo/NBO_0000342	http://purl.obolibrary.org/obo/UPHENO_0080280
+http://purl.obolibrary.org/obo/GO_0030099	http://purl.obolibrary.org/obo/UPHENO_0005488
diff --git a/src/curation/upheno-fillers/mp/abnormallyDecreasedRateOfBiologicalProcessInLocation.tsv b/src/curation/upheno-fillers/mp/abnormallyDecreasedRateOfBiologicalProcessInLocation.tsv
new file mode 100644
index 00000000..b86a0d50
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormallyDecreasedRateOfBiologicalProcessInLocation.tsv
@@ -0,0 +1,35 @@
+biological_process	location	defined_class
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0015249	http://purl.obolibrary.org/obo/UPHENO_0077870
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0000955	http://purl.obolibrary.org/obo/UPHENO_0081628
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0000019	http://purl.obolibrary.org/obo/UPHENO_0077871
+http://purl.obolibrary.org/obo/GO_0008015	http://purl.obolibrary.org/obo/UBERON_0002113	http://purl.obolibrary.org/obo/UPHENO_0081629
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0002097	http://purl.obolibrary.org/obo/UPHENO_0077874
+http://purl.obolibrary.org/obo/GO_0043473	http://purl.obolibrary.org/obo/UBERON_0001513	http://purl.obolibrary.org/obo/UPHENO_0077875
+http://purl.obolibrary.org/obo/GO_0043473	http://purl.obolibrary.org/obo/UBERON_0000468	http://purl.obolibrary.org/obo/UPHENO_0077877
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0001820	http://purl.obolibrary.org/obo/UPHENO_0077878
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0001621	http://purl.obolibrary.org/obo/UPHENO_0081630
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0002115	http://purl.obolibrary.org/obo/UPHENO_0077879
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0002116	http://purl.obolibrary.org/obo/UPHENO_0077880
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+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0016475	http://purl.obolibrary.org/obo/UPHENO_0077883
+http://purl.obolibrary.org/obo/GO_0014827	http://purl.obolibrary.org/obo/UBERON_0000381	http://purl.obolibrary.org/obo/UPHENO_0077884
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0002113	http://purl.obolibrary.org/obo/UPHENO_0081631
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+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0001513	http://purl.obolibrary.org/obo/UPHENO_0077888
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0000468	http://purl.obolibrary.org/obo/UPHENO_0077889
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+http://purl.obolibrary.org/obo/GO_0046903	http://purl.obolibrary.org/obo/UBERON_0001820	http://purl.obolibrary.org/obo/UPHENO_0077897
+http://purl.obolibrary.org/obo/GO_0014827	http://purl.obolibrary.org/obo/UBERON_0002116	http://purl.obolibrary.org/obo/UPHENO_0077898
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+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0001869	http://purl.obolibrary.org/obo/UPHENO_0081635
diff --git a/src/curation/upheno-fillers/mp/abnormallyDecreasedRateOfMolecularFunction.tsv b/src/curation/upheno-fillers/mp/abnormallyDecreasedRateOfMolecularFunction.tsv
new file mode 100644
index 00000000..42d88678
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormallyDecreasedRateOfMolecularFunction.tsv
@@ -0,0 +1,31 @@
+molecular_function	defined_class
+http://purl.obolibrary.org/obo/GO_0003990	http://purl.obolibrary.org/obo/UPHENO_0066856
+http://purl.obolibrary.org/obo/GO_0003870	http://purl.obolibrary.org/obo/UPHENO_0066857
+http://purl.obolibrary.org/obo/GO_0004365	http://purl.obolibrary.org/obo/UPHENO_0066858
+http://purl.obolibrary.org/obo/GO_0004585	http://purl.obolibrary.org/obo/UPHENO_0066859
+http://purl.obolibrary.org/obo/GO_0004340	http://purl.obolibrary.org/obo/UPHENO_0066860
+http://purl.obolibrary.org/obo/GO_0004104	http://purl.obolibrary.org/obo/UPHENO_0066861
+http://purl.obolibrary.org/obo/GO_0004743	http://purl.obolibrary.org/obo/UPHENO_0066862
+http://purl.obolibrary.org/obo/GO_0004102	http://purl.obolibrary.org/obo/UPHENO_0066863
+http://purl.obolibrary.org/obo/GO_0004465	http://purl.obolibrary.org/obo/UPHENO_0066864
+http://purl.obolibrary.org/obo/GO_0003674	http://purl.obolibrary.org/obo/UPHENO_0066865
+http://purl.obolibrary.org/obo/GO_0004601	http://purl.obolibrary.org/obo/UPHENO_0066866
+http://purl.obolibrary.org/obo/GO_0004602	http://purl.obolibrary.org/obo/UPHENO_0066868
+http://purl.obolibrary.org/obo/GO_0004607	http://purl.obolibrary.org/obo/UPHENO_0066869
+http://purl.obolibrary.org/obo/GO_0004806	http://purl.obolibrary.org/obo/UPHENO_0066870
+http://purl.obolibrary.org/obo/GO_0016206	http://purl.obolibrary.org/obo/UPHENO_0066871
+http://purl.obolibrary.org/obo/GO_0004096	http://purl.obolibrary.org/obo/UPHENO_0066872
+http://purl.obolibrary.org/obo/GO_0008474	http://purl.obolibrary.org/obo/UPHENO_0066873
+http://purl.obolibrary.org/obo/GO_0008112	http://purl.obolibrary.org/obo/UPHENO_0066874
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diff --git a/src/curation/upheno-fillers/mp/abnormallyDecreasedSizeOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/mp/abnormallyDecreasedSizeOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..ae98e2cc
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormallyDecreasedSizeOfAnatomicalEntity.tsv
@@ -0,0 +1,337 @@
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diff --git a/src/curation/upheno-fillers/mp/abnormallyDecreasedSizeOfCellularComponent.tsv b/src/curation/upheno-fillers/mp/abnormallyDecreasedSizeOfCellularComponent.tsv
new file mode 100644
index 00000000..34ab7441
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormallyDecreasedSizeOfCellularComponent.tsv
@@ -0,0 +1,7 @@
+entity	defined_class
+http://purl.obolibrary.org/obo/GO_0005739	http://purl.obolibrary.org/obo/UPHENO_0082011
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+http://purl.obolibrary.org/obo/GO_0005575	http://purl.obolibrary.org/obo/UPHENO_0082013
diff --git a/src/curation/upheno-fillers/mp/abnormallyDecreasedStrengthOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/mp/abnormallyDecreasedStrengthOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..0cbdda44
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormallyDecreasedStrengthOfAnatomicalEntity.tsv
@@ -0,0 +1,8 @@
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+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0080555
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diff --git a/src/curation/upheno-fillers/mp/abnormallyDecreasedThicknessOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/mp/abnormallyDecreasedThicknessOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..a44b1be3
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormallyDecreasedThicknessOfAnatomicalEntity.tsv
@@ -0,0 +1,82 @@
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+http://purl.obolibrary.org/obo/UBERON_0016915	http://purl.obolibrary.org/obo/UPHENO_0080776
+http://purl.obolibrary.org/obo/UBERON_0001752	http://purl.obolibrary.org/obo/UPHENO_0080777
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+http://purl.obolibrary.org/obo/UBERON_0000086	http://purl.obolibrary.org/obo/UPHENO_0080820
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+http://purl.obolibrary.org/obo/UBERON_0000956	http://purl.obolibrary.org/obo/UPHENO_0080827
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+http://purl.obolibrary.org/obo/UBERON_0002974	http://purl.obolibrary.org/obo/UPHENO_0080832
+http://purl.obolibrary.org/obo/UBERON_0001643	http://purl.obolibrary.org/obo/UPHENO_0080833
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+http://purl.obolibrary.org/obo/UBERON_0001437	http://purl.obolibrary.org/obo/UPHENO_0080839
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+http://purl.obolibrary.org/obo/UBERON_0036286	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001835	http://purl.obolibrary.org/obo/UPHENO_0080853
+http://purl.obolibrary.org/obo/UBERON_0036285	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001834	http://purl.obolibrary.org/obo/UPHENO_0080841
+http://purl.obolibrary.org/obo/UBERON_0036288	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0008829	http://purl.obolibrary.org/obo/UPHENO_0080842
diff --git a/src/curation/upheno-fillers/mp/abnormallyDecreasedTonicityOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/mp/abnormallyDecreasedTonicityOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..2564cb2f
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormallyDecreasedTonicityOfAnatomicalEntity.tsv
@@ -0,0 +1,4 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0082555
+http://purl.obolibrary.org/obo/UBERON_0000014	http://purl.obolibrary.org/obo/UPHENO_0082556
+http://purl.obolibrary.org/obo/UBERON_0001630	http://purl.obolibrary.org/obo/UPHENO_0082557
diff --git a/src/curation/upheno-fillers/mp/abnormallyDecreasedVolumeOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/mp/abnormallyDecreasedVolumeOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..d76227fc
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormallyDecreasedVolumeOfAnatomicalEntity.tsv
@@ -0,0 +1,12 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0078429
+http://purl.obolibrary.org/obo/UBERON_0002483	http://purl.obolibrary.org/obo/UPHENO_0078430
+http://purl.obolibrary.org/obo/CL_0000232	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001954	http://purl.obolibrary.org/obo/UPHENO_0078431
+http://purl.obolibrary.org/obo/UBERON_0001439	http://purl.obolibrary.org/obo/UPHENO_0078432
+http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0078433
+http://purl.obolibrary.org/obo/UBERON_0006723	http://purl.obolibrary.org/obo/UPHENO_0078434
+http://purl.obolibrary.org/obo/UBERON_0001890	http://purl.obolibrary.org/obo/UPHENO_0078435
+http://purl.obolibrary.org/obo/UBERON_0002110	http://purl.obolibrary.org/obo/UPHENO_0078436
+http://purl.obolibrary.org/obo/UBERON_0008883	http://purl.obolibrary.org/obo/UPHENO_0078437
+http://purl.obolibrary.org/obo/UBERON_0001474	http://purl.obolibrary.org/obo/UPHENO_0078438
diff --git a/src/curation/upheno-fillers/mp/abnormallyDecreasedWeightOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/mp/abnormallyDecreasedWeightOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..cb91b685
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormallyDecreasedWeightOfAnatomicalEntity.tsv
@@ -0,0 +1,59 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0010414	http://purl.obolibrary.org/obo/UPHENO_0054302
+http://purl.obolibrary.org/obo/UBERON_0002084	http://purl.obolibrary.org/obo/UPHENO_0054305
+http://purl.obolibrary.org/obo/CL_0000000	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0010412	http://purl.obolibrary.org/obo/UPHENO_0054307
+http://purl.obolibrary.org/obo/UBERON_0002483	http://purl.obolibrary.org/obo/UPHENO_0082016
+http://purl.obolibrary.org/obo/UBERON_0010413	http://purl.obolibrary.org/obo/UPHENO_0054309
+http://purl.obolibrary.org/obo/UBERON_0002240	http://purl.obolibrary.org/obo/UPHENO_0078398
+http://purl.obolibrary.org/obo/UBERON_0002080	http://purl.obolibrary.org/obo/UPHENO_0054311
+http://purl.obolibrary.org/obo/CL_0000169	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0000981	http://purl.obolibrary.org/obo/UPHENO_0054314
+http://purl.obolibrary.org/obo/UBERON_0002048	http://purl.obolibrary.org/obo/UPHENO_0054250
+http://purl.obolibrary.org/obo/UBERON_0001630	http://purl.obolibrary.org/obo/UPHENO_0054249
+http://purl.obolibrary.org/obo/UBERON_0002367	http://purl.obolibrary.org/obo/UPHENO_0054316
+http://purl.obolibrary.org/obo/UBERON_0007615	http://purl.obolibrary.org/obo/UPHENO_0084001
+http://purl.obolibrary.org/obo/UBERON_0002369	http://purl.obolibrary.org/obo/UPHENO_0054317
+http://purl.obolibrary.org/obo/UBERON_0001153	http://purl.obolibrary.org/obo/UPHENO_0082017
+http://purl.obolibrary.org/obo/UBERON_0001474	http://purl.obolibrary.org/obo/UPHENO_0054254
+http://purl.obolibrary.org/obo/UBERON_0002046	http://purl.obolibrary.org/obo/UPHENO_0054257
+http://purl.obolibrary.org/obo/UBERON_0001987	http://purl.obolibrary.org/obo/UPHENO_0054258
+http://purl.obolibrary.org/obo/UBERON_0001348	http://purl.obolibrary.org/obo/UPHENO_0082018
+http://purl.obolibrary.org/obo/UBERON_0003889	http://purl.obolibrary.org/obo/UPHENO_0054259
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0054261
+http://purl.obolibrary.org/obo/UBERON_0001301	http://purl.obolibrary.org/obo/UPHENO_0054330
+http://purl.obolibrary.org/obo/UBERON_0001389	http://purl.obolibrary.org/obo/UPHENO_0054331
+http://purl.obolibrary.org/obo/UBERON_0001388	http://purl.obolibrary.org/obo/UPHENO_0054333
+http://purl.obolibrary.org/obo/UBERON_0001347	http://purl.obolibrary.org/obo/UPHENO_0082019
+http://purl.obolibrary.org/obo/UBERON_0002078	http://purl.obolibrary.org/obo/UPHENO_0054336
+http://purl.obolibrary.org/obo/UBERON_0001264	http://purl.obolibrary.org/obo/UPHENO_0054337
+http://purl.obolibrary.org/obo/CL_0000171	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002113	http://purl.obolibrary.org/obo/UPHENO_0054338
+http://purl.obolibrary.org/obo/UBERON_0001386	http://purl.obolibrary.org/obo/UPHENO_0054339
+http://purl.obolibrary.org/obo/UBERON_0002079	http://purl.obolibrary.org/obo/UPHENO_0054341
+http://purl.obolibrary.org/obo/UBERON_0003916	http://purl.obolibrary.org/obo/UPHENO_0054263
+http://purl.obolibrary.org/obo/UBERON_0002107	http://purl.obolibrary.org/obo/UPHENO_0054345
+http://purl.obolibrary.org/obo/UBERON_0000007	http://purl.obolibrary.org/obo/UPHENO_0054265
+http://purl.obolibrary.org/obo/UBERON_0008807	http://purl.obolibrary.org/obo/UPHENO_0084002
+http://purl.obolibrary.org/obo/UBERON_0008808	http://purl.obolibrary.org/obo/UPHENO_0084003
+http://purl.obolibrary.org/obo/UBERON_0010410	http://purl.obolibrary.org/obo/UPHENO_0054350
+http://purl.obolibrary.org/obo/UBERON_0010411	http://purl.obolibrary.org/obo/UPHENO_0054351
+http://purl.obolibrary.org/obo/UBERON_0001377	http://purl.obolibrary.org/obo/UPHENO_0054360
+http://purl.obolibrary.org/obo/UBERON_0000323	http://purl.obolibrary.org/obo/UPHENO_0054362
+http://purl.obolibrary.org/obo/UBERON_0002106	http://purl.obolibrary.org/obo/UPHENO_0054363
+http://purl.obolibrary.org/obo/UBERON_0001134	http://purl.obolibrary.org/obo/UPHENO_0054366
+http://purl.obolibrary.org/obo/UBERON_0001255	http://purl.obolibrary.org/obo/UPHENO_0054367
+http://purl.obolibrary.org/obo/UBERON_0001723	http://purl.obolibrary.org/obo/UPHENO_0054279
+http://purl.obolibrary.org/obo/UBERON_0000996	http://purl.obolibrary.org/obo/UPHENO_0054280
+http://purl.obolibrary.org/obo/UBERON_0003427	http://purl.obolibrary.org/obo/UPHENO_0054371
+http://purl.obolibrary.org/obo/UBERON_0000998	http://purl.obolibrary.org/obo/UPHENO_0054282
+http://purl.obolibrary.org/obo/UBERON_0000955	http://purl.obolibrary.org/obo/UPHENO_0054372
+http://purl.obolibrary.org/obo/UBERON_0003428	http://purl.obolibrary.org/obo/UPHENO_0054373
+http://purl.obolibrary.org/obo/UBERON_0002370	http://purl.obolibrary.org/obo/UPHENO_0054285
+http://purl.obolibrary.org/obo/UBERON_0000992	http://purl.obolibrary.org/obo/UPHENO_0054289
+http://purl.obolibrary.org/obo/UBERON_0000995	http://purl.obolibrary.org/obo/UPHENO_0054290
+http://purl.obolibrary.org/obo/UBERON_0000473	http://purl.obolibrary.org/obo/UPHENO_0054295
+http://purl.obolibrary.org/obo/UBERON_0000947	http://purl.obolibrary.org/obo/UPHENO_0082020
+http://purl.obolibrary.org/obo/UBERON_0000948	http://purl.obolibrary.org/obo/UPHENO_0054385
+http://purl.obolibrary.org/obo/UBERON_0000468	http://purl.obolibrary.org/obo/UPHENO_0054299
+http://purl.obolibrary.org/obo/UBERON_0001439	http://purl.obolibrary.org/obo/UPHENO_0082021
diff --git a/src/curation/upheno-fillers/mp/abnormallyDecreasedWetnessOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/mp/abnormallyDecreasedWetnessOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..04d72bd1
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormallyDecreasedWetnessOfAnatomicalEntity.tsv
@@ -0,0 +1,6 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0000996	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0000019	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001037	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0000165	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/mp/abnormallyDecreasedWidthOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/mp/abnormallyDecreasedWidthOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..2a5c2fef
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormallyDecreasedWidthOfAnatomicalEntity.tsv
@@ -0,0 +1,16 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0054567
+http://purl.obolibrary.org/obo/UBERON_0004066	http://purl.obolibrary.org/obo/UPHENO_0054551
+http://purl.obolibrary.org/obo/UBERON_0006333	http://purl.obolibrary.org/obo/UPHENO_0054596
+http://purl.obolibrary.org/obo/UBERON_0006772	http://purl.obolibrary.org/obo/UPHENO_0054597
+http://purl.obolibrary.org/obo/UBERON_0003128	http://purl.obolibrary.org/obo/UPHENO_0054570
+http://purl.obolibrary.org/obo/UBERON_0001456	http://purl.obolibrary.org/obo/UPHENO_0054588
+http://purl.obolibrary.org/obo/UBERON_0002397	http://purl.obolibrary.org/obo/UPHENO_0054572
+http://purl.obolibrary.org/obo/UBERON_0000165	http://purl.obolibrary.org/obo/UPHENO_0054647
+http://purl.obolibrary.org/obo/UBERON_0000033	http://purl.obolibrary.org/obo/UPHENO_0054609
+http://purl.obolibrary.org/obo/UBERON_0001716	http://purl.obolibrary.org/obo/UPHENO_0054610
+http://purl.obolibrary.org/obo/UBERON_0001837	http://purl.obolibrary.org/obo/UPHENO_0054611
+http://purl.obolibrary.org/obo/UBERON_0001706	http://purl.obolibrary.org/obo/UPHENO_0054562
+http://purl.obolibrary.org/obo/UBERON_0001844	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0003715	http://purl.obolibrary.org/obo/UPHENO_0054575
+http://purl.obolibrary.org/obo/UBERON_0001819	http://purl.obolibrary.org/obo/UPHENO_0054577
diff --git a/src/curation/upheno-fillers/mp/abnormallyDelayedBiologicalProcess.tsv b/src/curation/upheno-fillers/mp/abnormallyDelayedBiologicalProcess.tsv
new file mode 100644
index 00000000..30342fb9
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormallyDelayedBiologicalProcess.tsv
@@ -0,0 +1,25 @@
+biological_process	defined_class
+http://purl.obolibrary.org/obo/GO_0007567	http://purl.obolibrary.org/obo/UPHENO_0083037
+http://purl.obolibrary.org/obo/GO_0003006	http://purl.obolibrary.org/obo/UPHENO_0000511
+http://purl.obolibrary.org/obo/GO_0044691	http://purl.obolibrary.org/obo/UPHENO_0000512
+http://purl.obolibrary.org/obo/GO_0042060	http://purl.obolibrary.org/obo/UPHENO_0000534
+http://purl.obolibrary.org/obo/GO_0097421	http://purl.obolibrary.org/obo/UPHENO_0076948
+http://purl.obolibrary.org/obo/GO_0061053	http://purl.obolibrary.org/obo/UPHENO_0000515
+http://purl.obolibrary.org/obo/GO_0060186	http://purl.obolibrary.org/obo/UPHENO_0000517
+http://purl.obolibrary.org/obo/GO_0060197	http://purl.obolibrary.org/obo/UPHENO_0000536
+http://purl.obolibrary.org/obo/GO_0007566	http://purl.obolibrary.org/obo/UPHENO_0000519
+http://purl.obolibrary.org/obo/GO_0042640	http://purl.obolibrary.org/obo/UPHENO_0000537
+http://purl.obolibrary.org/obo/GO_0042696	http://purl.obolibrary.org/obo/UPHENO_0000522
+http://purl.obolibrary.org/obo/GO_0060710	http://purl.obolibrary.org/obo/UPHENO_0076946
+http://purl.obolibrary.org/obo/GO_0009566	http://purl.obolibrary.org/obo/UPHENO_0000523
+http://purl.obolibrary.org/obo/GO_0043403	http://purl.obolibrary.org/obo/UPHENO_0083038
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UPHENO_0000543
+http://purl.obolibrary.org/obo/GO_0061026	http://purl.obolibrary.org/obo/UPHENO_0083039
+http://purl.obolibrary.org/obo/GO_0060322	http://purl.obolibrary.org/obo/UPHENO_0000526
+http://purl.obolibrary.org/obo/GO_0001503	http://purl.obolibrary.org/obo/UPHENO_0000527
+http://purl.obolibrary.org/obo/GO_0001822	http://purl.obolibrary.org/obo/UPHENO_0000528
+http://purl.obolibrary.org/obo/GO_0001957	http://purl.obolibrary.org/obo/UPHENO_0000546
+http://purl.obolibrary.org/obo/GO_0035483	http://purl.obolibrary.org/obo/UPHENO_0000547
+http://purl.obolibrary.org/obo/GO_0001958	http://purl.obolibrary.org/obo/UPHENO_0000550
+http://purl.obolibrary.org/obo/GO_0048839	http://purl.obolibrary.org/obo/UPHENO_0000531
+http://purl.obolibrary.org/obo/GO_0060209	http://purl.obolibrary.org/obo/UPHENO_0000532
diff --git a/src/curation/upheno-fillers/mp/abnormallyDelayedBiologicalProcessInLocation.tsv b/src/curation/upheno-fillers/mp/abnormallyDelayedBiologicalProcessInLocation.tsv
new file mode 100644
index 00000000..d78c0ae3
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormallyDelayedBiologicalProcessInLocation.tsv
@@ -0,0 +1,11 @@
+biological_process	location	defined_class
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0001017	http://purl.obolibrary.org/obo/UPHENO_0084007
+http://purl.obolibrary.org/obo/GO_0042246	http://purl.obolibrary.org/obo/UBERON_0001264	http://purl.obolibrary.org/obo/UPHENO_0084008
+http://purl.obolibrary.org/obo/GO_0042246	http://purl.obolibrary.org/obo/UBERON_0000160	http://purl.obolibrary.org/obo/UPHENO_0084009
+http://purl.obolibrary.org/obo/GO_0042246	http://purl.obolibrary.org/obo/UBERON_0001017	http://purl.obolibrary.org/obo/UPHENO_0084010
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0001630	http://purl.obolibrary.org/obo/UPHENO_0084011
+http://purl.obolibrary.org/obo/GO_0042246	http://purl.obolibrary.org/obo/UBERON_0000010	http://purl.obolibrary.org/obo/UPHENO_0084013
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0000160	http://purl.obolibrary.org/obo/UPHENO_0084014
+http://purl.obolibrary.org/obo/GO_0042246	http://purl.obolibrary.org/obo/UBERON_0001630	http://purl.obolibrary.org/obo/UPHENO_0084015
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0001264	http://purl.obolibrary.org/obo/UPHENO_0084017
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0000010	http://purl.obolibrary.org/obo/UPHENO_0084018
diff --git a/src/curation/upheno-fillers/mp/abnormallyDetachedAnatomicalEntities.tsv b/src/curation/upheno-fillers/mp/abnormallyDetachedAnatomicalEntities.tsv
new file mode 100644
index 00000000..83f806bc
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormallyDetachedAnatomicalEntities.tsv
@@ -0,0 +1,16 @@
+anatomical_entity	anatomical_entity_detached_from	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0002276	http://purl.obolibrary.org/obo/UPHENO_0081657
+http://purl.obolibrary.org/obo/GO_0001669	http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0008266	http://purl.obolibrary.org/obo/UBERON_0001753	http://purl.obolibrary.org/obo/UPHENO_0081658
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/GO_0001673	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002165	http://purl.obolibrary.org/obo/UBERON_0002349	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002233	http://purl.obolibrary.org/obo/UBERON_0002276	http://purl.obolibrary.org/obo/UPHENO_0081661
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0001753	http://purl.obolibrary.org/obo/UPHENO_0081663
+http://purl.obolibrary.org/obo/UBERON_0002425	http://purl.obolibrary.org/obo/UBERON_0002349	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002165	http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0081667
+http://purl.obolibrary.org/obo/GO_0001669	http://purl.obolibrary.org/obo/GO_0001673	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002425	http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0008266	http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0081668
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0002349	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002233	http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0081669
diff --git a/src/curation/upheno-fillers/mp/abnormallyDilatedAnatomicalEntity.tsv b/src/curation/upheno-fillers/mp/abnormallyDilatedAnatomicalEntity.tsv
new file mode 100644
index 00000000..804a32f2
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormallyDilatedAnatomicalEntity.tsv
@@ -0,0 +1,76 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0002084	http://purl.obolibrary.org/obo/UPHENO_0084108
+http://purl.obolibrary.org/obo/UBERON_0002285	http://purl.obolibrary.org/obo/UPHENO_0084109
+http://purl.obolibrary.org/obo/UBERON_0002081	http://purl.obolibrary.org/obo/UPHENO_0084110
+http://purl.obolibrary.org/obo/UBERON_0002080	http://purl.obolibrary.org/obo/UPHENO_0084111
+http://purl.obolibrary.org/obo/UBERON_0002082	http://purl.obolibrary.org/obo/UPHENO_0084112
+http://purl.obolibrary.org/obo/UBERON_0002247	http://purl.obolibrary.org/obo/UPHENO_0084113
+http://purl.obolibrary.org/obo/UBERON_0001633	http://purl.obolibrary.org/obo/UPHENO_0084114
+http://purl.obolibrary.org/obo/UBERON_0001231	http://purl.obolibrary.org/obo/UPHENO_0084115
+http://purl.obolibrary.org/obo/UBERON_0001473	http://purl.obolibrary.org/obo/UPHENO_0084116
+http://purl.obolibrary.org/obo/UBERON_0001230	http://purl.obolibrary.org/obo/UPHENO_0084117
+http://purl.obolibrary.org/obo/UBERON_0002286	http://purl.obolibrary.org/obo/UPHENO_0084118
+http://purl.obolibrary.org/obo/UBERON_0005432	http://purl.obolibrary.org/obo/UPHENO_0084119
+http://purl.obolibrary.org/obo/UBERON_0001232	http://purl.obolibrary.org/obo/UPHENO_0084120
+http://purl.obolibrary.org/obo/GO_0005739	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001155	http://purl.obolibrary.org/obo/UPHENO_0084121
+http://purl.obolibrary.org/obo/UBERON_0001508	http://purl.obolibrary.org/obo/UPHENO_0084122
+http://purl.obolibrary.org/obo/UBERON_0003889	http://purl.obolibrary.org/obo/UPHENO_0084123
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0084124
+http://purl.obolibrary.org/obo/UBERON_0009744	http://purl.obolibrary.org/obo/UPHENO_0084125
+http://purl.obolibrary.org/obo/UBERON_0003120	http://purl.obolibrary.org/obo/UPHENO_0084126
+http://purl.obolibrary.org/obo/UBERON_0002073	http://purl.obolibrary.org/obo/UPHENO_0084127
+http://purl.obolibrary.org/obo/UBERON_0002394	http://purl.obolibrary.org/obo/UPHENO_0084128
+http://purl.obolibrary.org/obo/UBERON_0001983	http://purl.obolibrary.org/obo/UPHENO_0084129
+http://purl.obolibrary.org/obo/UBERON_0006517	http://purl.obolibrary.org/obo/UPHENO_0084130
+http://purl.obolibrary.org/obo/UBERON_0002115	http://purl.obolibrary.org/obo/UPHENO_0084131
+http://purl.obolibrary.org/obo/UBERON_0001224	http://purl.obolibrary.org/obo/UPHENO_0084132
+http://purl.obolibrary.org/obo/UBERON_0001982	http://purl.obolibrary.org/obo/UPHENO_0084133
+http://purl.obolibrary.org/obo/UBERON_0007329	http://purl.obolibrary.org/obo/UPHENO_0084134
+http://purl.obolibrary.org/obo/UBERON_0002078	http://purl.obolibrary.org/obo/UPHENO_0084135
+http://purl.obolibrary.org/obo/UBERON_0002110	http://purl.obolibrary.org/obo/UPHENO_0084136
+http://purl.obolibrary.org/obo/UBERON_0001263	http://purl.obolibrary.org/obo/UPHENO_0084137
+http://purl.obolibrary.org/obo/UBERON_0001860	http://purl.obolibrary.org/obo/UPHENO_0084138
+http://purl.obolibrary.org/obo/UBERON_0001343	http://purl.obolibrary.org/obo/UPHENO_0084139
+http://purl.obolibrary.org/obo/UBERON_0001981	http://purl.obolibrary.org/obo/UPHENO_0084140
+http://purl.obolibrary.org/obo/UBERON_0004212	http://purl.obolibrary.org/obo/UPHENO_0084141
+http://purl.obolibrary.org/obo/UBERON_0002079	http://purl.obolibrary.org/obo/UPHENO_0084142
+http://purl.obolibrary.org/obo/UBERON_0000056	http://purl.obolibrary.org/obo/UPHENO_0084143
+http://purl.obolibrary.org/obo/UBERON_0003959	http://purl.obolibrary.org/obo/UPHENO_0084144
+http://purl.obolibrary.org/obo/UBERON_0000325	http://purl.obolibrary.org/obo/UPHENO_0084145
+http://purl.obolibrary.org/obo/UBERON_0010172	http://purl.obolibrary.org/obo/UPHENO_0084146
+http://purl.obolibrary.org/obo/UBERON_0010173	http://purl.obolibrary.org/obo/UPHENO_0084147
+http://purl.obolibrary.org/obo/UBERON_0035610	http://purl.obolibrary.org/obo/UPHENO_0084148
+http://purl.obolibrary.org/obo/UBERON_0004363	http://purl.obolibrary.org/obo/UPHENO_0084149
+http://purl.obolibrary.org/obo/UBERON_0001292	http://purl.obolibrary.org/obo/UPHENO_0084150
+http://purl.obolibrary.org/obo/UBERON_0004086	http://purl.obolibrary.org/obo/UPHENO_0084151
+http://purl.obolibrary.org/obo/UBERON_0006946	http://purl.obolibrary.org/obo/UPHENO_0084152
+http://purl.obolibrary.org/obo/UBERON_0000002	http://purl.obolibrary.org/obo/UPHENO_0084153
+http://purl.obolibrary.org/obo/UBERON_0001212	http://purl.obolibrary.org/obo/UPHENO_0084154
+http://purl.obolibrary.org/obo/UBERON_0002422	http://purl.obolibrary.org/obo/UPHENO_0084155
+http://purl.obolibrary.org/obo/UBERON_0002187	http://purl.obolibrary.org/obo/UPHENO_0084156
+http://purl.obolibrary.org/obo/UBERON_0002223	http://purl.obolibrary.org/obo/UPHENO_0084157
+http://purl.obolibrary.org/obo/UBERON_0001496	http://purl.obolibrary.org/obo/UPHENO_0084158
+http://purl.obolibrary.org/obo/UBERON_0001771	http://purl.obolibrary.org/obo/UPHENO_0084159
+http://purl.obolibrary.org/obo/UBERON_0001844	http://purl.obolibrary.org/obo/UPHENO_0084160
+http://purl.obolibrary.org/obo/UBERON_0001843	http://purl.obolibrary.org/obo/UPHENO_0084161
+http://purl.obolibrary.org/obo/UBERON_0000117	http://purl.obolibrary.org/obo/UPHENO_0084162
+http://purl.obolibrary.org/obo/UBERON_0000998	http://purl.obolibrary.org/obo/UPHENO_0084163
+http://purl.obolibrary.org/obo/UBERON_0005968	http://purl.obolibrary.org/obo/UPHENO_0084164
+http://purl.obolibrary.org/obo/GO_0016529	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002173	http://purl.obolibrary.org/obo/UPHENO_0084706
+http://purl.obolibrary.org/obo/UBERON_0002295	http://purl.obolibrary.org/obo/UPHENO_0084166
+http://purl.obolibrary.org/obo/UBERON_0001842	http://purl.obolibrary.org/obo/UPHENO_0084167
+http://purl.obolibrary.org/obo/UBERON_0001841	http://purl.obolibrary.org/obo/UPHENO_0084168
+http://purl.obolibrary.org/obo/UBERON_0000995	http://purl.obolibrary.org/obo/UPHENO_0084169
+http://purl.obolibrary.org/obo/UBERON_0002012	http://purl.obolibrary.org/obo/UPHENO_0084170
+http://purl.obolibrary.org/obo/UBERON_0001043	http://purl.obolibrary.org/obo/UPHENO_0084171
+http://purl.obolibrary.org/obo/UBERON_0001285	http://purl.obolibrary.org/obo/UPHENO_0084172
+http://purl.obolibrary.org/obo/UBERON_0002333	http://purl.obolibrary.org/obo/UPHENO_0084173
+http://purl.obolibrary.org/obo/UBERON_0001287	http://purl.obolibrary.org/obo/UPHENO_0084174
+http://purl.obolibrary.org/obo/UBERON_0001639	http://purl.obolibrary.org/obo/UPHENO_0084175
+http://purl.obolibrary.org/obo/UBERON_0010190	http://purl.obolibrary.org/obo/UPHENO_0084176
+http://purl.obolibrary.org/obo/UBERON_0000947	http://purl.obolibrary.org/obo/UPHENO_0084177
+http://purl.obolibrary.org/obo/UBERON_0003937	http://purl.obolibrary.org/obo/UPHENO_0084178
+http://purl.obolibrary.org/obo/UBERON_0000948	http://purl.obolibrary.org/obo/UPHENO_0084179
+http://purl.obolibrary.org/obo/UBERON_0001514	http://purl.obolibrary.org/obo/UPHENO_0084180
diff --git a/src/curation/upheno-fillers/mp/abnormallyDuplicatedAnatomicalEntity.tsv b/src/curation/upheno-fillers/mp/abnormallyDuplicatedAnatomicalEntity.tsv
new file mode 100644
index 00000000..c7e3d882
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormallyDuplicatedAnatomicalEntity.tsv
@@ -0,0 +1,8 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0075340
+http://purl.obolibrary.org/obo/UBERON_0001072	http://purl.obolibrary.org/obo/UPHENO_0075326
+http://purl.obolibrary.org/obo/GO_0036126	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002083	http://purl.obolibrary.org/obo/UPHENO_0075332
+http://purl.obolibrary.org/obo/UBERON_0001224	http://purl.obolibrary.org/obo/UPHENO_0075342
+http://purl.obolibrary.org/obo/GO_0061827	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0000056	http://purl.obolibrary.org/obo/UPHENO_0075347
diff --git a/src/curation/upheno-fillers/mp/abnormallyEvertedAnatomicalEntity.tsv b/src/curation/upheno-fillers/mp/abnormallyEvertedAnatomicalEntity.tsv
new file mode 100644
index 00000000..223c4928
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormallyEvertedAnatomicalEntity.tsv
@@ -0,0 +1,5 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0080241
+http://purl.obolibrary.org/obo/UBERON_0004022	http://purl.obolibrary.org/obo/UPHENO_0080242
+http://purl.obolibrary.org/obo/UBERON_0001833	http://purl.obolibrary.org/obo/UPHENO_0080243
+http://purl.obolibrary.org/obo/UBERON_0001711	http://purl.obolibrary.org/obo/UPHENO_0080244
diff --git a/src/curation/upheno-fillers/mp/abnormallyFusedAnatomicalEntities.tsv b/src/curation/upheno-fillers/mp/abnormallyFusedAnatomicalEntities.tsv
new file mode 100644
index 00000000..11933cf9
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormallyFusedAnatomicalEntities.tsv
@@ -0,0 +1,150 @@
+anatomical_entity	anatomical_entity_fused_with	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001688	http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0078057
+http://purl.obolibrary.org/obo/UBERON_0002414	http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0078058
+http://purl.obolibrary.org/obo/UBERON_0001740	http://purl.obolibrary.org/obo/UBERON_0002375	http://purl.obolibrary.org/obo/UPHENO_0078059
+http://purl.obolibrary.org/obo/UBERON_0002375	http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0078060
+http://purl.obolibrary.org/obo/UBERON_0003861	http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0078061
+http://purl.obolibrary.org/obo/UBERON_0001075	http://purl.obolibrary.org/obo/UBERON_0001075	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0003221	http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0078062
+http://purl.obolibrary.org/obo/UBERON_0002374	http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0078063
+http://purl.obolibrary.org/obo/UBERON_0001753	http://purl.obolibrary.org/obo/UBERON_0004103	http://purl.obolibrary.org/obo/UPHENO_0078064
+http://purl.obolibrary.org/obo/UBERON_0003451	http://purl.obolibrary.org/obo/UBERON_0003451	http://purl.obolibrary.org/obo/UPHENO_0078065
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+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0001424	http://purl.obolibrary.org/obo/UPHENO_0078190
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0002113	http://purl.obolibrary.org/obo/UPHENO_0078192
+http://purl.obolibrary.org/obo/UBERON_0002374	http://purl.obolibrary.org/obo/UBERON_0002374	http://purl.obolibrary.org/obo/UPHENO_0078193
+http://purl.obolibrary.org/obo/UBERON_0001688	http://purl.obolibrary.org/obo/UBERON_0001689	http://purl.obolibrary.org/obo/UPHENO_0078194
+http://purl.obolibrary.org/obo/UBERON_0002412	http://purl.obolibrary.org/obo/UBERON_0002412	http://purl.obolibrary.org/obo/UPHENO_0078195
+http://purl.obolibrary.org/obo/UBERON_0011597	http://purl.obolibrary.org/obo/UBERON_0004768	http://purl.obolibrary.org/obo/UPHENO_0078196
+http://purl.obolibrary.org/obo/UBERON_0001092	http://purl.obolibrary.org/obo/UBERON_0001676	http://purl.obolibrary.org/obo/UPHENO_0078197
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0000057	http://purl.obolibrary.org/obo/UPHENO_0078198
+http://purl.obolibrary.org/obo/UBERON_0001093	http://purl.obolibrary.org/obo/UBERON_0001676	http://purl.obolibrary.org/obo/UPHENO_0083738
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0003604	http://purl.obolibrary.org/obo/UPHENO_0078199
diff --git a/src/curation/upheno-fillers/mp/abnormallyGlisteningAnatomicalEntity.tsv b/src/curation/upheno-fillers/mp/abnormallyGlisteningAnatomicalEntity.tsv
new file mode 100644
index 00000000..b78d6c87
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormallyGlisteningAnatomicalEntity.tsv
@@ -0,0 +1,4 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0000014	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0010166	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/mp/abnormallyGreasyAnatomicalEntity.tsv b/src/curation/upheno-fillers/mp/abnormallyGreasyAnatomicalEntity.tsv
new file mode 100644
index 00000000..6d44a410
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormallyGreasyAnatomicalEntity.tsv
@@ -0,0 +1,4 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001037	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0000014	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/mp/abnormallyIncompleteClosureOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/mp/abnormallyIncompleteClosureOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..b58caf4c
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormallyIncompleteClosureOfAnatomicalEntity.tsv
@@ -0,0 +1,15 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0002085	http://purl.obolibrary.org/obo/UPHENO_0033559
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0033572
+http://purl.obolibrary.org/obo/UBERON_0003682	http://purl.obolibrary.org/obo/UPHENO_0033574
+http://purl.obolibrary.org/obo/UBERON_0005440	http://purl.obolibrary.org/obo/UPHENO_0033603
+http://purl.obolibrary.org/obo/UBERON_0002083	http://purl.obolibrary.org/obo/UPHENO_0033563
+http://purl.obolibrary.org/obo/UBERON_0002094	http://purl.obolibrary.org/obo/UPHENO_0033604
+http://purl.obolibrary.org/obo/UBERON_0003216	http://purl.obolibrary.org/obo/UPHENO_0033564
+http://purl.obolibrary.org/obo/UBERON_0003128	http://purl.obolibrary.org/obo/UPHENO_0033576
+http://purl.obolibrary.org/obo/UBERON_0002068	http://purl.obolibrary.org/obo/UPHENO_0033597
+http://purl.obolibrary.org/obo/UBERON_0001733	http://purl.obolibrary.org/obo/UPHENO_0033582
+http://purl.obolibrary.org/obo/UBERON_0012074	http://purl.obolibrary.org/obo/UPHENO_0033583
+http://purl.obolibrary.org/obo/UBERON_0000019	http://purl.obolibrary.org/obo/UPHENO_0033569
+http://purl.obolibrary.org/obo/UBERON_0005071	http://purl.obolibrary.org/obo/UPHENO_0033570
+http://purl.obolibrary.org/obo/UBERON_0005070	http://purl.obolibrary.org/obo/UPHENO_0033571
diff --git a/src/curation/upheno-fillers/mp/abnormallyIncreasedCoilingOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/mp/abnormallyIncreasedCoilingOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..e9d4e279
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormallyIncreasedCoilingOfAnatomicalEntity.tsv
@@ -0,0 +1,3 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001844	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/mp/abnormallyIncreasedHeightOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/mp/abnormallyIncreasedHeightOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..7f312f1b
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormallyIncreasedHeightOfAnatomicalEntity.tsv
@@ -0,0 +1,6 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0063513
+http://purl.obolibrary.org/obo/UBERON_0001716	http://purl.obolibrary.org/obo/UPHENO_0063527
+http://purl.obolibrary.org/obo/UBERON_0000468	http://purl.obolibrary.org/obo/UPHENO_0063528
+http://purl.obolibrary.org/obo/UBERON_0003128	http://purl.obolibrary.org/obo/UPHENO_0063523
+http://purl.obolibrary.org/obo/UBERON_0008200	http://purl.obolibrary.org/obo/UPHENO_0063525
diff --git a/src/curation/upheno-fillers/mp/abnormallyIncreasedLengthOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/mp/abnormallyIncreasedLengthOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..3ecd445e
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormallyIncreasedLengthOfAnatomicalEntity.tsv
@@ -0,0 +1,51 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0003450	http://purl.obolibrary.org/obo/UPHENO_0072254
+http://purl.obolibrary.org/obo/UBERON_0003451	http://purl.obolibrary.org/obo/UPHENO_0072256
+http://purl.obolibrary.org/obo/UBERON_0001075	http://purl.obolibrary.org/obo/UPHENO_0072181
+http://purl.obolibrary.org/obo/UBERON_0007812	http://purl.obolibrary.org/obo/UPHENO_0072260
+http://purl.obolibrary.org/obo/UBERON_0000981	http://purl.obolibrary.org/obo/UPHENO_0072262
+http://purl.obolibrary.org/obo/UBERON_0001037	http://purl.obolibrary.org/obo/UPHENO_0072261
+http://purl.obolibrary.org/obo/UBERON_0001155	http://purl.obolibrary.org/obo/UPHENO_0072267
+http://purl.obolibrary.org/obo/UBERON_0001705	http://purl.obolibrary.org/obo/UPHENO_0072268
+http://purl.obolibrary.org/obo/UBERON_0000979	http://purl.obolibrary.org/obo/UPHENO_0072269
+http://purl.obolibrary.org/obo/UBERON_0001228	http://purl.obolibrary.org/obo/UPHENO_0072189
+http://purl.obolibrary.org/obo/UBERON_0000974	http://purl.obolibrary.org/obo/UPHENO_0072272
+http://purl.obolibrary.org/obo/UBERON_0000976	http://purl.obolibrary.org/obo/UPHENO_0072275
+http://purl.obolibrary.org/obo/UBERON_0001702	http://purl.obolibrary.org/obo/UPHENO_0072394
+http://purl.obolibrary.org/obo/UBERON_0010222	http://purl.obolibrary.org/obo/UPHENO_0072194
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+http://purl.obolibrary.org/obo/UBERON_0003128	http://purl.obolibrary.org/obo/UPHENO_0072199
+http://purl.obolibrary.org/obo/UBERON_0000059	http://purl.obolibrary.org/obo/UPHENO_0072283
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+http://purl.obolibrary.org/obo/UBERON_0001424	http://purl.obolibrary.org/obo/UPHENO_0072284
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+http://purl.obolibrary.org/obo/UBERON_0002397	http://purl.obolibrary.org/obo/UPHENO_0072202
+http://purl.obolibrary.org/obo/UBERON_0002108	http://purl.obolibrary.org/obo/UPHENO_0072289
+http://purl.obolibrary.org/obo/UBERON_0002228	http://purl.obolibrary.org/obo/UPHENO_0072290
+http://purl.obolibrary.org/obo/UBERON_0000160	http://purl.obolibrary.org/obo/UPHENO_0072295
+http://purl.obolibrary.org/obo/UBERON_0001691	http://purl.obolibrary.org/obo/UPHENO_0072352
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+http://purl.obolibrary.org/obo/UBERON_0002544	http://purl.obolibrary.org/obo/UPHENO_0072215
+http://purl.obolibrary.org/obo/UBERON_0002103	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001456	http://purl.obolibrary.org/obo/UPHENO_0072219
+http://purl.obolibrary.org/obo/GO_0001917	http://purl.obolibrary.org/obo/UPHENO_0084757
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+http://purl.obolibrary.org/obo/GO_0000781	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001448	http://purl.obolibrary.org/obo/UPHENO_0072223
+http://purl.obolibrary.org/obo/UBERON_0001844	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0001750	http://purl.obolibrary.org/obo/UPHENO_0084757
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+http://purl.obolibrary.org/obo/GO_0043197	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0006333	http://purl.obolibrary.org/obo/UPHENO_0072230
+http://purl.obolibrary.org/obo/GO_0036126	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001446	http://purl.obolibrary.org/obo/UPHENO_0072238
+http://purl.obolibrary.org/obo/UBERON_0002374	http://purl.obolibrary.org/obo/UPHENO_0072242
+http://purl.obolibrary.org/obo/UBERON_0002495	http://purl.obolibrary.org/obo/UPHENO_0072241
+http://purl.obolibrary.org/obo/UBERON_0001684	http://purl.obolibrary.org/obo/UPHENO_0072245
+http://purl.obolibrary.org/obo/UBERON_0001716	http://purl.obolibrary.org/obo/UPHENO_0072247
+http://purl.obolibrary.org/obo/GO_0002177	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0000468	http://purl.obolibrary.org/obo/UPHENO_0072251
+http://purl.obolibrary.org/obo/UBERON_0010231	http://purl.obolibrary.org/obo/UPHENO_0072326
diff --git a/src/curation/upheno-fillers/mp/abnormallyIncreasedLevelOfChemicalEntity.tsv b/src/curation/upheno-fillers/mp/abnormallyIncreasedLevelOfChemicalEntity.tsv
new file mode 100644
index 00000000..ad95a659
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormallyIncreasedLevelOfChemicalEntity.tsv
@@ -0,0 +1,74 @@
+chemical_entity	defined_class
+http://purl.obolibrary.org/obo/CHEBI_26125	http://purl.obolibrary.org/obo/UPHENO_0048691
+http://purl.obolibrary.org/obo/CHEBI_24741	http://purl.obolibrary.org/obo/UPHENO_0048692
+http://purl.obolibrary.org/obo/CHEBI_16919	http://purl.obolibrary.org/obo/UPHENO_0048693
+http://purl.obolibrary.org/obo/CHEBI_28300	http://purl.obolibrary.org/obo/UPHENO_0048694
+http://purl.obolibrary.org/obo/PR_000007785	http://purl.obolibrary.org/obo/UPHENO_0048695
+http://purl.obolibrary.org/obo/CHEBI_15428	http://purl.obolibrary.org/obo/UPHENO_0048696
+http://purl.obolibrary.org/obo/CHEBI_16958	http://purl.obolibrary.org/obo/UPHENO_0048697
+http://purl.obolibrary.org/obo/CHEBI_18132	http://purl.obolibrary.org/obo/UPHENO_0084749
+http://purl.obolibrary.org/obo/CHEBI_16393	http://purl.obolibrary.org/obo/UPHENO_0048698
+http://purl.obolibrary.org/obo/CHEBI_26607	http://purl.obolibrary.org/obo/UPHENO_0048699
+http://purl.obolibrary.org/obo/CHEBI_8337	http://purl.obolibrary.org/obo/UPHENO_0048700
+http://purl.obolibrary.org/obo/CHEBI_30660	http://purl.obolibrary.org/obo/UPHENO_0048701
+http://purl.obolibrary.org/obo/CHEBI_18059	http://purl.obolibrary.org/obo/UPHENO_0048763
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+http://purl.obolibrary.org/obo/CHEBI_25805	http://purl.obolibrary.org/obo/UPHENO_0048720
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+http://purl.obolibrary.org/obo/PR_000002107	http://purl.obolibrary.org/obo/UPHENO_0084403
+http://purl.obolibrary.org/obo/CHEBI_26986	http://purl.obolibrary.org/obo/UPHENO_0048722
+http://purl.obolibrary.org/obo/PR_000003809	http://purl.obolibrary.org/obo/UPHENO_0048751
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+http://purl.obolibrary.org/obo/CHEBI_28892	http://purl.obolibrary.org/obo/UPHENO_0084757
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+http://purl.obolibrary.org/obo/CHEBI_81568	http://purl.obolibrary.org/obo/UPHENO_0048742
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+http://purl.obolibrary.org/obo/PR_000016480	http://purl.obolibrary.org/obo/UPHENO_0084404
+http://purl.obolibrary.org/obo/CHEBI_15355	http://purl.obolibrary.org/obo/UPHENO_0048749
diff --git a/src/curation/upheno-fillers/mp/abnormallyIncreasedLevelOfChemicalEntityInLocation.tsv b/src/curation/upheno-fillers/mp/abnormallyIncreasedLevelOfChemicalEntityInLocation.tsv
new file mode 100644
index 00000000..b12a88ee
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormallyIncreasedLevelOfChemicalEntityInLocation.tsv
@@ -0,0 +1,238 @@
+chemical_entity	location	defined_class
+http://purl.obolibrary.org/obo/CHEBI_28087	http://purl.obolibrary.org/obo/UBERON_0002107	http://purl.obolibrary.org/obo/UPHENO_0067994
+http://purl.obolibrary.org/obo/CHEBI_28300	http://purl.obolibrary.org/obo/UBERON_0001088	http://purl.obolibrary.org/obo/UPHENO_0067995
+http://purl.obolibrary.org/obo/CHEBI_24431	http://purl.obolibrary.org/obo/UBERON_0002048	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CHEBI_30052	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0068001
+http://purl.obolibrary.org/obo/PR_000000134	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0068005
+http://purl.obolibrary.org/obo/CHEBI_33568	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0068008
+http://purl.obolibrary.org/obo/CHEBI_28694	http://purl.obolibrary.org/obo/UBERON_0002298	http://purl.obolibrary.org/obo/UPHENO_0068018
+http://purl.obolibrary.org/obo/CHEBI_26271	http://purl.obolibrary.org/obo/UBERON_0001088	http://purl.obolibrary.org/obo/UPHENO_0068019
+http://purl.obolibrary.org/obo/CHEBI_30860	http://purl.obolibrary.org/obo/UBERON_0001088	http://purl.obolibrary.org/obo/UPHENO_0068023
+http://purl.obolibrary.org/obo/CHEBI_27226	http://purl.obolibrary.org/obo/UBERON_0001088	http://purl.obolibrary.org/obo/UPHENO_0068024
+http://purl.obolibrary.org/obo/CHEBI_27584	http://purl.obolibrary.org/obo/UBERON_0001088	http://purl.obolibrary.org/obo/UPHENO_0068026
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+http://purl.obolibrary.org/obo/PR_000000017	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0068033
+http://purl.obolibrary.org/obo/CHEBI_75431	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0068034
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+http://purl.obolibrary.org/obo/PR_000001392	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0068273
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+http://purl.obolibrary.org/obo/CHEBI_16134	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0068277
+http://purl.obolibrary.org/obo/PR_000001387	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0068279
+http://purl.obolibrary.org/obo/CHEBI_22984	http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0068280
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diff --git a/src/curation/upheno-fillers/mp/abnormallyIncreasedLevelOfChemicalEntityWithRoleInLocation.tsv b/src/curation/upheno-fillers/mp/abnormallyIncreasedLevelOfChemicalEntityWithRoleInLocation.tsv
new file mode 100644
index 00000000..c2947d87
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormallyIncreasedLevelOfChemicalEntityWithRoleInLocation.tsv
@@ -0,0 +1,3 @@
+location	role	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001088	http://purl.obolibrary.org/obo/CHEBI_24621	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001088	http://purl.obolibrary.org/obo/CHEBI_50906	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/mp/abnormallyIncreasedMassDensityOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/mp/abnormallyIncreasedMassDensityOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..8489ac8b
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormallyIncreasedMassDensityOfAnatomicalEntity.tsv
@@ -0,0 +1,3 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0084449
+http://purl.obolibrary.org/obo/UBERON_0001474	http://purl.obolibrary.org/obo/UPHENO_0084450
diff --git a/src/curation/upheno-fillers/mp/abnormallyIncreasedNumberOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/mp/abnormallyIncreasedNumberOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..9982d1f8
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormallyIncreasedNumberOfAnatomicalEntity.tsv
@@ -0,0 +1,195 @@
+anatomical_entity	defined_class
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+http://purl.obolibrary.org/obo/CL_0002066	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000561	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000202	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0003655	http://purl.obolibrary.org/obo/UPHENO_0014231
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diff --git a/src/curation/upheno-fillers/mp/abnormallyIncreasedNumberOfAnatomicalEntityInLocation.tsv b/src/curation/upheno-fillers/mp/abnormallyIncreasedNumberOfAnatomicalEntityInLocation.tsv
new file mode 100644
index 00000000..f66b4354
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormallyIncreasedNumberOfAnatomicalEntityInLocation.tsv
@@ -0,0 +1,42 @@
+anatomical_entity	location	defined_class
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+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0001474	http://purl.obolibrary.org/obo/UPHENO_0055993
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+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0015813	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0003221	http://purl.obolibrary.org/obo/UBERON_0002544	http://purl.obolibrary.org/obo/UPHENO_0056007
+http://purl.obolibrary.org/obo/UBERON_0001702	http://purl.obolibrary.org/obo/UBERON_0001456	http://purl.obolibrary.org/obo/UPHENO_0056079
+http://purl.obolibrary.org/obo/CL_0000000	http://purl.obolibrary.org/obo/UBERON_0001992	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002544	http://purl.obolibrary.org/obo/UBERON_0002101	http://purl.obolibrary.org/obo/UPHENO_0056085
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0002113	http://purl.obolibrary.org/obo/UPHENO_0056091
+http://purl.obolibrary.org/obo/UBERON_0001771	http://purl.obolibrary.org/obo/UBERON_0001769	http://purl.obolibrary.org/obo/UPHENO_0056016
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0002106	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000598	http://purl.obolibrary.org/obo/UBERON_0000956	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0001456	http://purl.obolibrary.org/obo/UPHENO_0056024
+http://purl.obolibrary.org/obo/GO_0005811	http://purl.obolibrary.org/obo/UBERON_0001348	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0002544	http://purl.obolibrary.org/obo/UPHENO_0056029
+http://purl.obolibrary.org/obo/UBERON_0003221	http://purl.obolibrary.org/obo/UBERON_0006048	http://purl.obolibrary.org/obo/UPHENO_0056030
+http://purl.obolibrary.org/obo/UBERON_0001232	http://purl.obolibrary.org/obo/UBERON_0002113	http://purl.obolibrary.org/obo/UPHENO_0056031
+http://purl.obolibrary.org/obo/GO_0031514	http://purl.obolibrary.org/obo/CL_0002368	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0002101	http://purl.obolibrary.org/obo/UPHENO_0056112
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0000956	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001013	http://purl.obolibrary.org/obo/UBERON_0000916	http://purl.obolibrary.org/obo/UPHENO_0056035
+http://purl.obolibrary.org/obo/CL_0000160	http://purl.obolibrary.org/obo/UBERON_0015813	http://purl.obolibrary.org/obo/UPHENO_0084757
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+http://purl.obolibrary.org/obo/CL_0000598	http://purl.obolibrary.org/obo/UBERON_0001954	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001419	http://purl.obolibrary.org/obo/UBERON_0006012	http://purl.obolibrary.org/obo/UPHENO_0056049
+http://purl.obolibrary.org/obo/CL_0000000	http://purl.obolibrary.org/obo/UBERON_0008266	http://purl.obolibrary.org/obo/UPHENO_0084757
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+http://purl.obolibrary.org/obo/CL_0000023	http://purl.obolibrary.org/obo/UBERON_0001305	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0000916	http://purl.obolibrary.org/obo/UPHENO_0056059
+http://purl.obolibrary.org/obo/CL_0000763	http://purl.obolibrary.org/obo/UBERON_0002371	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0001769	http://purl.obolibrary.org/obo/UPHENO_0056140
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0006012	http://purl.obolibrary.org/obo/UPHENO_0056143
+http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UBERON_0001088	http://purl.obolibrary.org/obo/UPHENO_0056192
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diff --git a/src/curation/upheno-fillers/mp/abnormallyIncreasedNumberOfCellularComponent.tsv b/src/curation/upheno-fillers/mp/abnormallyIncreasedNumberOfCellularComponent.tsv
new file mode 100644
index 00000000..c45573c9
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormallyIncreasedNumberOfCellularComponent.tsv
@@ -0,0 +1,14 @@
+cellular_component	defined_class
+http://purl.obolibrary.org/obo/GO_0043197	http://purl.obolibrary.org/obo/UPHENO_0083031
+http://purl.obolibrary.org/obo/GO_0005575	http://purl.obolibrary.org/obo/UPHENO_0063672
+http://purl.obolibrary.org/obo/GO_0002185	http://purl.obolibrary.org/obo/UPHENO_0063673
+http://purl.obolibrary.org/obo/GO_0005634	http://purl.obolibrary.org/obo/UPHENO_0063674
+http://purl.obolibrary.org/obo/GO_0001750	http://purl.obolibrary.org/obo/UPHENO_0063677
+http://purl.obolibrary.org/obo/GO_0042827	http://purl.obolibrary.org/obo/UPHENO_0063669
+http://purl.obolibrary.org/obo/GO_0005739	http://purl.obolibrary.org/obo/UPHENO_0063670
+http://purl.obolibrary.org/obo/GO_0097208	http://purl.obolibrary.org/obo/UPHENO_0063671
+http://purl.obolibrary.org/obo/GO_0061827	http://purl.obolibrary.org/obo/UPHENO_0084422
+http://purl.obolibrary.org/obo/GO_0031091	http://purl.obolibrary.org/obo/UPHENO_0063675
+http://purl.obolibrary.org/obo/GO_0042613	http://purl.obolibrary.org/obo/UPHENO_0063676
+http://purl.obolibrary.org/obo/GO_0042612	http://purl.obolibrary.org/obo/UPHENO_0063678
+http://purl.obolibrary.org/obo/GO_0036126	http://purl.obolibrary.org/obo/UPHENO_0084423
diff --git a/src/curation/upheno-fillers/mp/abnormallyIncreasedPigmentationOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/mp/abnormallyIncreasedPigmentationOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..adeb56b5
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormallyIncreasedPigmentationOfAnatomicalEntity.tsv
@@ -0,0 +1,3 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0010666
+http://purl.obolibrary.org/obo/UBERON_0015484	http://purl.obolibrary.org/obo/UPHENO_0010676
diff --git a/src/curation/upheno-fillers/mp/abnormallyIncreasedQualityOfBiologicalProcess.tsv b/src/curation/upheno-fillers/mp/abnormallyIncreasedQualityOfBiologicalProcess.tsv
new file mode 100644
index 00000000..d8d1c456
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormallyIncreasedQualityOfBiologicalProcess.tsv
@@ -0,0 +1,11 @@
+biological_process	defined_class
+http://purl.obolibrary.org/obo/NBO_0001987	http://purl.obolibrary.org/obo/UPHENO_0080661
+http://purl.obolibrary.org/obo/GO_0043403	http://purl.obolibrary.org/obo/UPHENO_0083259
+http://purl.obolibrary.org/obo/GO_0040038	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0097421	http://purl.obolibrary.org/obo/UPHENO_0080720
+http://purl.obolibrary.org/obo/GO_0030317	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UPHENO_0080662
+http://purl.obolibrary.org/obo/GO_0061026	http://purl.obolibrary.org/obo/UPHENO_0080742
+http://purl.obolibrary.org/obo/GO_0042628	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0044321	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0007056	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/mp/abnormallyIncreasedQualityOfBiologicalProcessInLocation.tsv b/src/curation/upheno-fillers/mp/abnormallyIncreasedQualityOfBiologicalProcessInLocation.tsv
new file mode 100644
index 00000000..b5442e20
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormallyIncreasedQualityOfBiologicalProcessInLocation.tsv
@@ -0,0 +1,11 @@
+biological_process	location	defined_class
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0001017	http://purl.obolibrary.org/obo/UPHENO_0084209
+http://purl.obolibrary.org/obo/GO_0042246	http://purl.obolibrary.org/obo/UBERON_0001264	http://purl.obolibrary.org/obo/UPHENO_0084210
+http://purl.obolibrary.org/obo/GO_0042246	http://purl.obolibrary.org/obo/UBERON_0000160	http://purl.obolibrary.org/obo/UPHENO_0084211
+http://purl.obolibrary.org/obo/GO_0042246	http://purl.obolibrary.org/obo/UBERON_0001017	http://purl.obolibrary.org/obo/UPHENO_0084212
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0001630	http://purl.obolibrary.org/obo/UPHENO_0084213
+http://purl.obolibrary.org/obo/GO_0042246	http://purl.obolibrary.org/obo/UBERON_0000010	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0000160	http://purl.obolibrary.org/obo/UPHENO_0084214
+http://purl.obolibrary.org/obo/GO_0042246	http://purl.obolibrary.org/obo/UBERON_0001630	http://purl.obolibrary.org/obo/UPHENO_0084215
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0001264	http://purl.obolibrary.org/obo/UPHENO_0084216
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0000010	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/mp/abnormallyIncreasedRateOfBehavior.tsv b/src/curation/upheno-fillers/mp/abnormallyIncreasedRateOfBehavior.tsv
new file mode 100644
index 00000000..11cb0115
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormallyIncreasedRateOfBehavior.tsv
@@ -0,0 +1,37 @@
+behavior_process	defined_class
+http://purl.obolibrary.org/obo/NBO_0000015	http://purl.obolibrary.org/obo/UPHENO_0012046
+http://purl.obolibrary.org/obo/NBO_0000214	http://purl.obolibrary.org/obo/UPHENO_0012048
+http://purl.obolibrary.org/obo/NBO_0000313	http://purl.obolibrary.org/obo/UPHENO_0012047
+http://purl.obolibrary.org/obo/NBO_0000159	http://purl.obolibrary.org/obo/UPHENO_0012049
+http://purl.obolibrary.org/obo/NBO_0000336	http://purl.obolibrary.org/obo/UPHENO_0012052
+http://purl.obolibrary.org/obo/NBO_0000578	http://purl.obolibrary.org/obo/UPHENO_0012051
+http://purl.obolibrary.org/obo/NBO_0000338	http://purl.obolibrary.org/obo/UPHENO_0084755
+http://purl.obolibrary.org/obo/NBO_0000339	http://purl.obolibrary.org/obo/UPHENO_0012054
+http://purl.obolibrary.org/obo/NBO_0000218	http://purl.obolibrary.org/obo/UPHENO_0012055
+http://purl.obolibrary.org/obo/NBO_0001728	http://purl.obolibrary.org/obo/UPHENO_0012056
+http://purl.obolibrary.org/obo/NBO_0002362	http://purl.obolibrary.org/obo/UPHENO_0012057
+http://purl.obolibrary.org/obo/NBO_0002065	http://purl.obolibrary.org/obo/UPHENO_0012058
+http://purl.obolibrary.org/obo/NBO_0000381	http://purl.obolibrary.org/obo/UPHENO_0012059
+http://purl.obolibrary.org/obo/NBO_0002021	http://purl.obolibrary.org/obo/UPHENO_0012060
+http://purl.obolibrary.org/obo/NBO_0000222	http://purl.obolibrary.org/obo/UPHENO_0012062
+http://purl.obolibrary.org/obo/NBO_0000223	http://purl.obolibrary.org/obo/UPHENO_0012063
+http://purl.obolibrary.org/obo/NBO_0000224	http://purl.obolibrary.org/obo/UPHENO_0012064
+http://purl.obolibrary.org/obo/NBO_0000103	http://purl.obolibrary.org/obo/UPHENO_0012065
+http://purl.obolibrary.org/obo/NBO_0000104	http://purl.obolibrary.org/obo/UPHENO_0012066
+http://purl.obolibrary.org/obo/NBO_0000027	http://purl.obolibrary.org/obo/UPHENO_0012067
+http://purl.obolibrary.org/obo/NBO_0001679	http://purl.obolibrary.org/obo/UPHENO_0012068
+http://purl.obolibrary.org/obo/NBO_0000107	http://purl.obolibrary.org/obo/UPHENO_0012069
+http://purl.obolibrary.org/obo/NBO_0000448	http://purl.obolibrary.org/obo/UPHENO_0012070
+http://purl.obolibrary.org/obo/NBO_0000091	http://purl.obolibrary.org/obo/UPHENO_0012071
+http://purl.obolibrary.org/obo/NBO_0000092	http://purl.obolibrary.org/obo/UPHENO_0012072
+http://purl.obolibrary.org/obo/NBO_0000391	http://purl.obolibrary.org/obo/UPHENO_0012073
+http://purl.obolibrary.org/obo/NBO_0000097	http://purl.obolibrary.org/obo/UPHENO_0012074
+http://purl.obolibrary.org/obo/NBO_0000131	http://purl.obolibrary.org/obo/UPHENO_0012075
+http://purl.obolibrary.org/obo/NBO_0000110	http://purl.obolibrary.org/obo/UPHENO_0012076
+http://purl.obolibrary.org/obo/NBO_0000111	http://purl.obolibrary.org/obo/UPHENO_0012078
+http://purl.obolibrary.org/obo/NBO_0000112	http://purl.obolibrary.org/obo/UPHENO_0012079
+http://purl.obolibrary.org/obo/NBO_0000211	http://purl.obolibrary.org/obo/UPHENO_0082947
+http://purl.obolibrary.org/obo/NBO_0000057	http://purl.obolibrary.org/obo/UPHENO_0012080
+http://purl.obolibrary.org/obo/NBO_0000332	http://purl.obolibrary.org/obo/UPHENO_0012081
+http://purl.obolibrary.org/obo/NBO_0000013	http://purl.obolibrary.org/obo/UPHENO_0084756
+http://purl.obolibrary.org/obo/NBO_0001763	http://purl.obolibrary.org/obo/UPHENO_0012082
diff --git a/src/curation/upheno-fillers/mp/abnormallyIncreasedRateOfBiologicalProcess.tsv b/src/curation/upheno-fillers/mp/abnormallyIncreasedRateOfBiologicalProcess.tsv
new file mode 100644
index 00000000..7107f7dc
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormallyIncreasedRateOfBiologicalProcess.tsv
@@ -0,0 +1,55 @@
+biological_process	defined_class
+http://purl.obolibrary.org/obo/NBO_0000448	http://purl.obolibrary.org/obo/UPHENO_0054934
+http://purl.obolibrary.org/obo/GO_0046951	http://purl.obolibrary.org/obo/UPHENO_0055032
+http://purl.obolibrary.org/obo/GO_0042637	http://purl.obolibrary.org/obo/UPHENO_0055033
+http://purl.obolibrary.org/obo/NBO_0000091	http://purl.obolibrary.org/obo/UPHENO_0082796
+http://purl.obolibrary.org/obo/NBO_0000092	http://purl.obolibrary.org/obo/UPHENO_0082797
+http://purl.obolibrary.org/obo/NBO_0000097	http://purl.obolibrary.org/obo/UPHENO_0082798
+http://purl.obolibrary.org/obo/NBO_0000131	http://purl.obolibrary.org/obo/UPHENO_0082799
+http://purl.obolibrary.org/obo/NBO_0000211	http://purl.obolibrary.org/obo/UPHENO_0082800
+http://purl.obolibrary.org/obo/NBO_0000057	http://purl.obolibrary.org/obo/UPHENO_0082801
+http://purl.obolibrary.org/obo/NBO_0000332	http://purl.obolibrary.org/obo/UPHENO_0082802
+http://purl.obolibrary.org/obo/GO_0030421	http://purl.obolibrary.org/obo/UPHENO_0055037
+http://purl.obolibrary.org/obo/NBO_0000013	http://purl.obolibrary.org/obo/UPHENO_0055038
+http://purl.obolibrary.org/obo/GO_0001550	http://purl.obolibrary.org/obo/UPHENO_0055042
+http://purl.obolibrary.org/obo/NBO_0000159	http://purl.obolibrary.org/obo/UPHENO_0054952
+http://purl.obolibrary.org/obo/GO_0070091	http://purl.obolibrary.org/obo/UPHENO_0055043
+http://purl.obolibrary.org/obo/GO_0001951	http://purl.obolibrary.org/obo/UPHENO_0055044
+http://purl.obolibrary.org/obo/GO_0045453	http://purl.obolibrary.org/obo/UPHENO_0055046
+http://purl.obolibrary.org/obo/GO_0003094	http://purl.obolibrary.org/obo/UPHENO_0054956
+http://purl.obolibrary.org/obo/NBO_0001728	http://purl.obolibrary.org/obo/UPHENO_0082803
+http://purl.obolibrary.org/obo/GO_0043473	http://purl.obolibrary.org/obo/UPHENO_0054957
+http://purl.obolibrary.org/obo/GO_0043396	http://purl.obolibrary.org/obo/UPHENO_0055047
+http://purl.obolibrary.org/obo/GO_0046541	http://purl.obolibrary.org/obo/UPHENO_0055048
+http://purl.obolibrary.org/obo/NBO_0002065	http://purl.obolibrary.org/obo/UPHENO_0082804
+http://purl.obolibrary.org/obo/GO_0006094	http://purl.obolibrary.org/obo/UPHENO_0054966
+http://purl.obolibrary.org/obo/GO_0040007	http://purl.obolibrary.org/obo/UPHENO_0054968
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UPHENO_0054970
+http://purl.obolibrary.org/obo/NBO_0002021	http://purl.obolibrary.org/obo/UPHENO_0082805
+http://purl.obolibrary.org/obo/NBO_0001679	http://purl.obolibrary.org/obo/UPHENO_0082806
+http://purl.obolibrary.org/obo/NBO_0000224	http://purl.obolibrary.org/obo/UPHENO_0082807
+http://purl.obolibrary.org/obo/NBO_0000103	http://purl.obolibrary.org/obo/UPHENO_0082808
+http://purl.obolibrary.org/obo/GO_0001542	http://purl.obolibrary.org/obo/UPHENO_0084707
+http://purl.obolibrary.org/obo/NBO_0000104	http://purl.obolibrary.org/obo/UPHENO_0082809
+http://purl.obolibrary.org/obo/NBO_0000027	http://purl.obolibrary.org/obo/UPHENO_0082810
+http://purl.obolibrary.org/obo/NBO_0000107	http://purl.obolibrary.org/obo/UPHENO_0082811
+http://purl.obolibrary.org/obo/GO_0005980	http://purl.obolibrary.org/obo/UPHENO_0054980
+http://purl.obolibrary.org/obo/NBO_0000391	http://purl.obolibrary.org/obo/UPHENO_0082812
+http://purl.obolibrary.org/obo/NBO_0000112	http://purl.obolibrary.org/obo/UPHENO_0082813
+http://purl.obolibrary.org/obo/NBO_0001763	http://purl.obolibrary.org/obo/UPHENO_0082814
+http://purl.obolibrary.org/obo/NBO_0000110	http://purl.obolibrary.org/obo/UPHENO_0082815
+http://purl.obolibrary.org/obo/NBO_0000111	http://purl.obolibrary.org/obo/UPHENO_0082816
+http://purl.obolibrary.org/obo/NBO_0000336	http://purl.obolibrary.org/obo/UPHENO_0082817
+http://purl.obolibrary.org/obo/NBO_0000578	http://purl.obolibrary.org/obo/UPHENO_0082818
+http://purl.obolibrary.org/obo/NBO_0000015	http://purl.obolibrary.org/obo/UPHENO_0082819
+http://purl.obolibrary.org/obo/NBO_0000214	http://purl.obolibrary.org/obo/UPHENO_0082820
+http://purl.obolibrary.org/obo/GO_0070075	http://purl.obolibrary.org/obo/UPHENO_0055080
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+http://purl.obolibrary.org/obo/GO_0060073	http://purl.obolibrary.org/obo/UPHENO_0055007
+http://purl.obolibrary.org/obo/NBO_0002362	http://purl.obolibrary.org/obo/UPHENO_0082823
+http://purl.obolibrary.org/obo/GO_0030252	http://purl.obolibrary.org/obo/UPHENO_0055017
+http://purl.obolibrary.org/obo/NBO_0000381	http://purl.obolibrary.org/obo/UPHENO_0055087
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+http://purl.obolibrary.org/obo/NBO_0000223	http://purl.obolibrary.org/obo/UPHENO_0082825
diff --git a/src/curation/upheno-fillers/mp/abnormallyIncreasedRateOfBiologicalProcessInLocation.tsv b/src/curation/upheno-fillers/mp/abnormallyIncreasedRateOfBiologicalProcessInLocation.tsv
new file mode 100644
index 00000000..70dbf7dd
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormallyIncreasedRateOfBiologicalProcessInLocation.tsv
@@ -0,0 +1,27 @@
+biological_process	location	defined_class
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0015249	http://purl.obolibrary.org/obo/UPHENO_0074569
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0000955	http://purl.obolibrary.org/obo/UPHENO_0081733
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+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UBERON_0002097	http://purl.obolibrary.org/obo/UPHENO_0074575
+http://purl.obolibrary.org/obo/GO_0043473	http://purl.obolibrary.org/obo/UBERON_0001513	http://purl.obolibrary.org/obo/UPHENO_0074576
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diff --git a/src/curation/upheno-fillers/mp/abnormallyIncreasedRateOfMolecularFunction.tsv b/src/curation/upheno-fillers/mp/abnormallyIncreasedRateOfMolecularFunction.tsv
new file mode 100644
index 00000000..428a3783
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormallyIncreasedRateOfMolecularFunction.tsv
@@ -0,0 +1,31 @@
+molecular_function	defined_class
+http://purl.obolibrary.org/obo/GO_0003990	http://purl.obolibrary.org/obo/UPHENO_0048652
+http://purl.obolibrary.org/obo/GO_0003870	http://purl.obolibrary.org/obo/UPHENO_0048653
+http://purl.obolibrary.org/obo/GO_0004365	http://purl.obolibrary.org/obo/UPHENO_0048654
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+http://purl.obolibrary.org/obo/GO_0004340	http://purl.obolibrary.org/obo/UPHENO_0048656
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+http://purl.obolibrary.org/obo/GO_0004743	http://purl.obolibrary.org/obo/UPHENO_0048658
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+http://purl.obolibrary.org/obo/GO_0050174	http://purl.obolibrary.org/obo/UPHENO_0048679
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+http://purl.obolibrary.org/obo/GO_0070547	http://purl.obolibrary.org/obo/UPHENO_0048682
diff --git a/src/curation/upheno-fillers/mp/abnormallyIncreasedSizeOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/mp/abnormallyIncreasedSizeOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..f1b3d6c0
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormallyIncreasedSizeOfAnatomicalEntity.tsv
@@ -0,0 +1,258 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0004187	http://purl.obolibrary.org/obo/UPHENO_0000950
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diff --git a/src/curation/upheno-fillers/mp/abnormallyIncreasedSizeOfCellularComponent.tsv b/src/curation/upheno-fillers/mp/abnormallyIncreasedSizeOfCellularComponent.tsv
new file mode 100644
index 00000000..1cb42aa3
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormallyIncreasedSizeOfCellularComponent.tsv
@@ -0,0 +1,8 @@
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+http://purl.obolibrary.org/obo/GO_0005739	http://purl.obolibrary.org/obo/UPHENO_0080307
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diff --git a/src/curation/upheno-fillers/mp/abnormallyIncreasedThicknessOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/mp/abnormallyIncreasedThicknessOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..8f51aec6
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormallyIncreasedThicknessOfAnatomicalEntity.tsv
@@ -0,0 +1,69 @@
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+http://purl.obolibrary.org/obo/UBERON_0004893	http://purl.obolibrary.org/obo/UPHENO_0047911
+http://purl.obolibrary.org/obo/UBERON_0001777	http://purl.obolibrary.org/obo/UPHENO_0047915
+http://purl.obolibrary.org/obo/UBERON_0000964	http://purl.obolibrary.org/obo/UPHENO_0047914
+http://purl.obolibrary.org/obo/UBERON_0002349	http://purl.obolibrary.org/obo/UPHENO_0047916
+http://purl.obolibrary.org/obo/UBERON_0011742	http://purl.obolibrary.org/obo/UPHENO_0047922
+http://purl.obolibrary.org/obo/UBERON_0001691	http://purl.obolibrary.org/obo/UPHENO_0047832
+http://purl.obolibrary.org/obo/UBERON_0005372	http://purl.obolibrary.org/obo/UPHENO_0047835
+http://purl.obolibrary.org/obo/UBERON_0005371	http://purl.obolibrary.org/obo/UPHENO_0047836
+http://purl.obolibrary.org/obo/UBERON_0007151	http://purl.obolibrary.org/obo/UPHENO_0047837
+http://purl.obolibrary.org/obo/UBERON_0002027	http://purl.obolibrary.org/obo/UPHENO_0047838
+http://purl.obolibrary.org/obo/UBERON_0002500	http://purl.obolibrary.org/obo/UPHENO_0047931
+http://purl.obolibrary.org/obo/UBERON_0002026	http://purl.obolibrary.org/obo/UPHENO_0047841
+http://purl.obolibrary.org/obo/UBERON_0005777	http://purl.obolibrary.org/obo/UPHENO_0047842
+http://purl.obolibrary.org/obo/UBERON_0004367	http://purl.obolibrary.org/obo/UPHENO_0082497
+http://purl.obolibrary.org/obo/UBERON_0002067	http://purl.obolibrary.org/obo/UPHENO_0047937
+http://purl.obolibrary.org/obo/UBERON_0004125	http://purl.obolibrary.org/obo/UPHENO_0047938
+http://purl.obolibrary.org/obo/UBERON_0008883	http://purl.obolibrary.org/obo/UPHENO_0047844
+http://purl.obolibrary.org/obo/UBERON_0001772	http://purl.obolibrary.org/obo/UPHENO_0047940
+http://purl.obolibrary.org/obo/UBERON_0002025	http://purl.obolibrary.org/obo/UPHENO_0047845
+http://purl.obolibrary.org/obo/UBERON_0002069	http://purl.obolibrary.org/obo/UPHENO_0047941
+http://purl.obolibrary.org/obo/UBERON_0002146	http://purl.obolibrary.org/obo/UPHENO_0047846
+http://purl.obolibrary.org/obo/UBERON_0004883	http://purl.obolibrary.org/obo/UPHENO_0047943
+http://purl.obolibrary.org/obo/UBERON_0000956	http://purl.obolibrary.org/obo/UPHENO_0047944
+http://purl.obolibrary.org/obo/UBERON_0001847	http://purl.obolibrary.org/obo/UPHENO_0047848
+http://purl.obolibrary.org/obo/UBERON_0003946	http://purl.obolibrary.org/obo/UPHENO_0047946
+http://purl.obolibrary.org/obo/GO_0043209	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0005484	http://purl.obolibrary.org/obo/UPHENO_0047855
+http://purl.obolibrary.org/obo/GO_0036126	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002094	http://purl.obolibrary.org/obo/UPHENO_0047856
+http://purl.obolibrary.org/obo/UBERON_0002137	http://purl.obolibrary.org/obo/UPHENO_0047858
+http://purl.obolibrary.org/obo/UBERON_0001003	http://purl.obolibrary.org/obo/UPHENO_0047953
+http://purl.obolibrary.org/obo/UBERON_0001242	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0004356	http://purl.obolibrary.org/obo/UPHENO_0047958
+http://purl.obolibrary.org/obo/UBERON_0005368	http://purl.obolibrary.org/obo/UPHENO_0047868
+http://purl.obolibrary.org/obo/UBERON_0002135	http://purl.obolibrary.org/obo/UPHENO_0047871
+http://purl.obolibrary.org/obo/UBERON_0002134	http://purl.obolibrary.org/obo/UPHENO_0047872
+http://purl.obolibrary.org/obo/UBERON_0001833	http://purl.obolibrary.org/obo/UPHENO_0047873
+http://purl.obolibrary.org/obo/UBERON_0001437	http://purl.obolibrary.org/obo/UPHENO_0047874
+http://purl.obolibrary.org/obo/UBERON_0001711	http://purl.obolibrary.org/obo/UPHENO_0047875
+http://purl.obolibrary.org/obo/UBERON_0001439	http://purl.obolibrary.org/obo/UPHENO_0047876
+http://purl.obolibrary.org/obo/UBERON_0036286	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001835	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0036285	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001834	http://purl.obolibrary.org/obo/UPHENO_0047878
+http://purl.obolibrary.org/obo/UBERON_0036288	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/mp/abnormallyIncreasedThicknessOfAnatomicalEntityInLocation.tsv b/src/curation/upheno-fillers/mp/abnormallyIncreasedThicknessOfAnatomicalEntityInLocation.tsv
new file mode 100644
index 00000000..53f80c92
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormallyIncreasedThicknessOfAnatomicalEntityInLocation.tsv
@@ -0,0 +1,5 @@
+anatomical_entity	location	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001703	http://purl.obolibrary.org/obo/UBERON_0003128	http://purl.obolibrary.org/obo/UPHENO_0048341
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0000981	http://purl.obolibrary.org/obo/UPHENO_0048317
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0003128	http://purl.obolibrary.org/obo/UPHENO_0048331
+http://purl.obolibrary.org/obo/UBERON_0016422	http://purl.obolibrary.org/obo/UBERON_0000981	http://purl.obolibrary.org/obo/UPHENO_0048319
diff --git a/src/curation/upheno-fillers/mp/abnormallyIncreasedVolumeOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/mp/abnormallyIncreasedVolumeOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..60557ba9
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormallyIncreasedVolumeOfAnatomicalEntity.tsv
@@ -0,0 +1,14 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0084715
+http://purl.obolibrary.org/obo/UBERON_0002483	http://purl.obolibrary.org/obo/UPHENO_0084716
+http://purl.obolibrary.org/obo/CL_0000232	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000233	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0000178	http://purl.obolibrary.org/obo/UPHENO_0084719
+http://purl.obolibrary.org/obo/UBERON_0001950	http://purl.obolibrary.org/obo/UPHENO_0084720
+http://purl.obolibrary.org/obo/UBERON_0006524	http://purl.obolibrary.org/obo/UPHENO_0084721
+http://purl.obolibrary.org/obo/UBERON_0001890	http://purl.obolibrary.org/obo/UPHENO_0084722
+http://purl.obolibrary.org/obo/UBERON_0002110	http://purl.obolibrary.org/obo/UPHENO_0084723
+http://purl.obolibrary.org/obo/UBERON_0008883	http://purl.obolibrary.org/obo/UPHENO_0084724
+http://purl.obolibrary.org/obo/UBERON_0001474	http://purl.obolibrary.org/obo/UPHENO_0084725
+http://purl.obolibrary.org/obo/UBERON_0001954	http://purl.obolibrary.org/obo/UPHENO_0084717
+http://purl.obolibrary.org/obo/UBERON_0001439	http://purl.obolibrary.org/obo/UPHENO_0084718
diff --git a/src/curation/upheno-fillers/mp/abnormallyIncreasedWeightOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/mp/abnormallyIncreasedWeightOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..406bc90a
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormallyIncreasedWeightOfAnatomicalEntity.tsv
@@ -0,0 +1,58 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0010414	http://purl.obolibrary.org/obo/UPHENO_0008315
+http://purl.obolibrary.org/obo/UBERON_0002084	http://purl.obolibrary.org/obo/UPHENO_0008318
+http://purl.obolibrary.org/obo/CL_0000000	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0010412	http://purl.obolibrary.org/obo/UPHENO_0008320
+http://purl.obolibrary.org/obo/UBERON_0002483	http://purl.obolibrary.org/obo/UPHENO_0080294
+http://purl.obolibrary.org/obo/UBERON_0010413	http://purl.obolibrary.org/obo/UPHENO_0008322
+http://purl.obolibrary.org/obo/UBERON_0002080	http://purl.obolibrary.org/obo/UPHENO_0008324
+http://purl.obolibrary.org/obo/CL_0000169	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0000981	http://purl.obolibrary.org/obo/UPHENO_0008327
+http://purl.obolibrary.org/obo/UBERON_0002048	http://purl.obolibrary.org/obo/UPHENO_0008263
+http://purl.obolibrary.org/obo/UBERON_0001630	http://purl.obolibrary.org/obo/UPHENO_0008262
+http://purl.obolibrary.org/obo/UBERON_0002367	http://purl.obolibrary.org/obo/UPHENO_0008329
+http://purl.obolibrary.org/obo/UBERON_0007615	http://purl.obolibrary.org/obo/UPHENO_0082955
+http://purl.obolibrary.org/obo/UBERON_0002369	http://purl.obolibrary.org/obo/UPHENO_0008330
+http://purl.obolibrary.org/obo/UBERON_0001153	http://purl.obolibrary.org/obo/UPHENO_0080295
+http://purl.obolibrary.org/obo/UBERON_0001474	http://purl.obolibrary.org/obo/UPHENO_0008266
+http://purl.obolibrary.org/obo/UBERON_0002046	http://purl.obolibrary.org/obo/UPHENO_0008269
+http://purl.obolibrary.org/obo/UBERON_0001987	http://purl.obolibrary.org/obo/UPHENO_0008270
+http://purl.obolibrary.org/obo/UBERON_0001348	http://purl.obolibrary.org/obo/UPHENO_0080296
+http://purl.obolibrary.org/obo/UBERON_0003889	http://purl.obolibrary.org/obo/UPHENO_0008271
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0008273
+http://purl.obolibrary.org/obo/UBERON_0001301	http://purl.obolibrary.org/obo/UPHENO_0008343
+http://purl.obolibrary.org/obo/UBERON_0001389	http://purl.obolibrary.org/obo/UPHENO_0008344
+http://purl.obolibrary.org/obo/UBERON_0001388	http://purl.obolibrary.org/obo/UPHENO_0008346
+http://purl.obolibrary.org/obo/UBERON_0001347	http://purl.obolibrary.org/obo/UPHENO_0080297
+http://purl.obolibrary.org/obo/UBERON_0002078	http://purl.obolibrary.org/obo/UPHENO_0008349
+http://purl.obolibrary.org/obo/UBERON_0001264	http://purl.obolibrary.org/obo/UPHENO_0008350
+http://purl.obolibrary.org/obo/UBERON_0001385	http://purl.obolibrary.org/obo/UPHENO_0008351
+http://purl.obolibrary.org/obo/CL_0000171	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002113	http://purl.obolibrary.org/obo/UPHENO_0008352
+http://purl.obolibrary.org/obo/UBERON_0001386	http://purl.obolibrary.org/obo/UPHENO_0008353
+http://purl.obolibrary.org/obo/UBERON_0002079	http://purl.obolibrary.org/obo/UPHENO_0008355
+http://purl.obolibrary.org/obo/UBERON_0003916	http://purl.obolibrary.org/obo/UPHENO_0008275
+http://purl.obolibrary.org/obo/UBERON_0002107	http://purl.obolibrary.org/obo/UPHENO_0008359
+http://purl.obolibrary.org/obo/UBERON_0000007	http://purl.obolibrary.org/obo/UPHENO_0008277
+http://purl.obolibrary.org/obo/UBERON_0008807	http://purl.obolibrary.org/obo/UPHENO_0082956
+http://purl.obolibrary.org/obo/UBERON_0008808	http://purl.obolibrary.org/obo/UPHENO_0082957
+http://purl.obolibrary.org/obo/UBERON_0010410	http://purl.obolibrary.org/obo/UPHENO_0008364
+http://purl.obolibrary.org/obo/UBERON_0010411	http://purl.obolibrary.org/obo/UPHENO_0008365
+http://purl.obolibrary.org/obo/UBERON_0001377	http://purl.obolibrary.org/obo/UPHENO_0008374
+http://purl.obolibrary.org/obo/UBERON_0000323	http://purl.obolibrary.org/obo/UPHENO_0008376
+http://purl.obolibrary.org/obo/UBERON_0002106	http://purl.obolibrary.org/obo/UPHENO_0008377
+http://purl.obolibrary.org/obo/UBERON_0001134	http://purl.obolibrary.org/obo/UPHENO_0008380
+http://purl.obolibrary.org/obo/UBERON_0001255	http://purl.obolibrary.org/obo/UPHENO_0008381
+http://purl.obolibrary.org/obo/UBERON_0000996	http://purl.obolibrary.org/obo/UPHENO_0008292
+http://purl.obolibrary.org/obo/UBERON_0003427	http://purl.obolibrary.org/obo/UPHENO_0008385
+http://purl.obolibrary.org/obo/UBERON_0000998	http://purl.obolibrary.org/obo/UPHENO_0008294
+http://purl.obolibrary.org/obo/UBERON_0000955	http://purl.obolibrary.org/obo/UPHENO_0008386
+http://purl.obolibrary.org/obo/UBERON_0003428	http://purl.obolibrary.org/obo/UPHENO_0008387
+http://purl.obolibrary.org/obo/UBERON_0002370	http://purl.obolibrary.org/obo/UPHENO_0008297
+http://purl.obolibrary.org/obo/UBERON_0000992	http://purl.obolibrary.org/obo/UPHENO_0008301
+http://purl.obolibrary.org/obo/UBERON_0000995	http://purl.obolibrary.org/obo/UPHENO_0008303
+http://purl.obolibrary.org/obo/UBERON_0000473	http://purl.obolibrary.org/obo/UPHENO_0008308
+http://purl.obolibrary.org/obo/UBERON_0000947	http://purl.obolibrary.org/obo/UPHENO_0080298
+http://purl.obolibrary.org/obo/UBERON_0000948	http://purl.obolibrary.org/obo/UPHENO_0008399
+http://purl.obolibrary.org/obo/UBERON_0000468	http://purl.obolibrary.org/obo/UPHENO_0008312
+http://purl.obolibrary.org/obo/UBERON_0001439	http://purl.obolibrary.org/obo/UPHENO_0080299
diff --git a/src/curation/upheno-fillers/mp/abnormallyIncreasedWidthOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/mp/abnormallyIncreasedWidthOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..5f62ffa0
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormallyIncreasedWidthOfAnatomicalEntity.tsv
@@ -0,0 +1,27 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0004066	http://purl.obolibrary.org/obo/UPHENO_0006139
+http://purl.obolibrary.org/obo/UBERON_0001273	http://purl.obolibrary.org/obo/UPHENO_0006143
+http://purl.obolibrary.org/obo/UBERON_0002489	http://purl.obolibrary.org/obo/UPHENO_0006145
+http://purl.obolibrary.org/obo/UBERON_0008340	http://purl.obolibrary.org/obo/UPHENO_0006147
+http://purl.obolibrary.org/obo/UBERON_0004347	http://purl.obolibrary.org/obo/UPHENO_0006150
+http://purl.obolibrary.org/obo/UBERON_0001456	http://purl.obolibrary.org/obo/UPHENO_0006186
+http://purl.obolibrary.org/obo/UBERON_0007119	http://purl.obolibrary.org/obo/UPHENO_0006187
+http://purl.obolibrary.org/obo/UBERON_0001676	http://purl.obolibrary.org/obo/UPHENO_0006152
+http://purl.obolibrary.org/obo/UBERON_0000165	http://purl.obolibrary.org/obo/UPHENO_0006476
+http://purl.obolibrary.org/obo/UBERON_0001706	http://purl.obolibrary.org/obo/UPHENO_0006156
+http://purl.obolibrary.org/obo/UBERON_0001844	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0000975	http://purl.obolibrary.org/obo/UPHENO_0006158
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0006161
+http://purl.obolibrary.org/obo/UBERON_0006333	http://purl.obolibrary.org/obo/UPHENO_0006203
+http://purl.obolibrary.org/obo/UBERON_0002492	http://purl.obolibrary.org/obo/UPHENO_0006204
+http://purl.obolibrary.org/obo/UBERON_0006772	http://purl.obolibrary.org/obo/UPHENO_0006206
+http://purl.obolibrary.org/obo/UBERON_0002491	http://purl.obolibrary.org/obo/UPHENO_0006207
+http://purl.obolibrary.org/obo/UBERON_0002490	http://purl.obolibrary.org/obo/UPHENO_0006210
+http://purl.obolibrary.org/obo/UBERON_0003128	http://purl.obolibrary.org/obo/UPHENO_0006164
+http://purl.obolibrary.org/obo/UBERON_0003685	http://purl.obolibrary.org/obo/UPHENO_0006166
+http://purl.obolibrary.org/obo/UBERON_0001681	http://purl.obolibrary.org/obo/UPHENO_0006220
+http://purl.obolibrary.org/obo/UBERON_0000033	http://purl.obolibrary.org/obo/UPHENO_0006222
+http://purl.obolibrary.org/obo/UBERON_0001716	http://purl.obolibrary.org/obo/UPHENO_0006225
+http://purl.obolibrary.org/obo/UBERON_0000209	http://purl.obolibrary.org/obo/UPHENO_0006169
+http://purl.obolibrary.org/obo/UBERON_0002228	http://purl.obolibrary.org/obo/UPHENO_0006170
+http://purl.obolibrary.org/obo/UBERON_0004747	http://purl.obolibrary.org/obo/UPHENO_0006227
diff --git a/src/curation/upheno-fillers/mp/abnormallyOpaqueAnatomicalEntity.tsv b/src/curation/upheno-fillers/mp/abnormallyOpaqueAnatomicalEntity.tsv
new file mode 100644
index 00000000..736ceff8
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormallyOpaqueAnatomicalEntity.tsv
@@ -0,0 +1,4 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0000965	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001798	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/mp/abnormallyOpenAnatomicalEntity.tsv b/src/curation/upheno-fillers/mp/abnormallyOpenAnatomicalEntity.tsv
new file mode 100644
index 00000000..d02af597
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormallyOpenAnatomicalEntity.tsv
@@ -0,0 +1,7 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0075655
+http://purl.obolibrary.org/obo/UBERON_0002137	http://purl.obolibrary.org/obo/UPHENO_0075656
+http://purl.obolibrary.org/obo/UBERON_0000165	http://purl.obolibrary.org/obo/UPHENO_0075662
+http://purl.obolibrary.org/obo/UBERON_0002135	http://purl.obolibrary.org/obo/UPHENO_0075657
+http://purl.obolibrary.org/obo/UBERON_0002146	http://purl.obolibrary.org/obo/UPHENO_0075658
+http://purl.obolibrary.org/obo/UBERON_0002134	http://purl.obolibrary.org/obo/UPHENO_0075659
diff --git a/src/curation/upheno-fillers/mp/abnormallyPrematureBiologicalProcess.tsv b/src/curation/upheno-fillers/mp/abnormallyPrematureBiologicalProcess.tsv
new file mode 100644
index 00000000..51af7bcb
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormallyPrematureBiologicalProcess.tsv
@@ -0,0 +1,10 @@
+biological_process	defined_class
+http://purl.obolibrary.org/obo/GO_0007567	http://purl.obolibrary.org/obo/UPHENO_0049449
+http://purl.obolibrary.org/obo/GO_0003006	http://purl.obolibrary.org/obo/UPHENO_0049451
+http://purl.obolibrary.org/obo/GO_0044691	http://purl.obolibrary.org/obo/UPHENO_0049436
+http://purl.obolibrary.org/obo/GO_0001942	http://purl.obolibrary.org/obo/UPHENO_0049437
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UPHENO_0049440
+http://purl.obolibrary.org/obo/GO_0060185	http://purl.obolibrary.org/obo/UPHENO_0049438
+http://purl.obolibrary.org/obo/GO_0001503	http://purl.obolibrary.org/obo/UPHENO_0049441
+http://purl.obolibrary.org/obo/GO_0001957	http://purl.obolibrary.org/obo/UPHENO_0049443
+http://purl.obolibrary.org/obo/GO_0001958	http://purl.obolibrary.org/obo/UPHENO_0049445
diff --git a/src/curation/upheno-fillers/mp/abnormallyProminentAnatomicalEntity.tsv b/src/curation/upheno-fillers/mp/abnormallyProminentAnatomicalEntity.tsv
new file mode 100644
index 00000000..c402adb7
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormallyProminentAnatomicalEntity.tsv
@@ -0,0 +1,8 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0082900
+http://purl.obolibrary.org/obo/UBERON_0001847	http://purl.obolibrary.org/obo/UPHENO_0082901
+http://purl.obolibrary.org/obo/UBERON_0001691	http://purl.obolibrary.org/obo/UPHENO_0082902
+http://purl.obolibrary.org/obo/UBERON_0008340	http://purl.obolibrary.org/obo/UPHENO_0082903
+http://purl.obolibrary.org/obo/UBERON_0001567	http://purl.obolibrary.org/obo/UPHENO_0082904
+http://purl.obolibrary.org/obo/UBERON_0008200	http://purl.obolibrary.org/obo/UPHENO_0082905
+http://purl.obolibrary.org/obo/UBERON_0001684	http://purl.obolibrary.org/obo/UPHENO_0082906
diff --git a/src/curation/upheno-fillers/mp/abnormallyProtrudingAnatomicalEntity.tsv b/src/curation/upheno-fillers/mp/abnormallyProtrudingAnatomicalEntity.tsv
new file mode 100644
index 00000000..34b7cc60
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormallyProtrudingAnatomicalEntity.tsv
@@ -0,0 +1,9 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002108	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002137	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0000995	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001066	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002135	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002146	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002134	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/mp/abnormallyRotatedAnatomicalEntity.tsv b/src/curation/upheno-fillers/mp/abnormallyRotatedAnatomicalEntity.tsv
new file mode 100644
index 00000000..a53b9473
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abnormallyRotatedAnatomicalEntity.tsv
@@ -0,0 +1,5 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0002470	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0082022
+http://purl.obolibrary.org/obo/UBERON_0000160	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001691	http://purl.obolibrary.org/obo/UPHENO_0082023
diff --git a/src/curation/upheno-fillers/mp/abscessInLocation.tsv b/src/curation/upheno-fillers/mp/abscessInLocation.tsv
new file mode 100644
index 00000000..7761b469
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/abscessInLocation.tsv
@@ -0,0 +1 @@
+abscess	anatomical_entity	defined_class
diff --git a/src/curation/upheno-fillers/mp/atreticAnatomicalEntity.tsv b/src/curation/upheno-fillers/mp/atreticAnatomicalEntity.tsv
new file mode 100644
index 00000000..f4168dbf
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/atreticAnatomicalEntity.tsv
@@ -0,0 +1,23 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0063565
+http://purl.obolibrary.org/obo/UBERON_0010425	http://purl.obolibrary.org/obo/UPHENO_0063595
+http://purl.obolibrary.org/obo/UBERON_0002394	http://purl.obolibrary.org/obo/UPHENO_0063622
+http://purl.obolibrary.org/obo/UBERON_0002137	http://purl.obolibrary.org/obo/UPHENO_0063597
+http://purl.obolibrary.org/obo/UBERON_0002115	http://purl.obolibrary.org/obo/UPHENO_0063567
+http://purl.obolibrary.org/obo/UBERON_0000057	http://purl.obolibrary.org/obo/UPHENO_0063568
+http://purl.obolibrary.org/obo/UBERON_0000002	http://purl.obolibrary.org/obo/UPHENO_0063587
+http://purl.obolibrary.org/obo/UBERON_0002114	http://purl.obolibrary.org/obo/UPHENO_0063569
+http://purl.obolibrary.org/obo/UBERON_0000159	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002116	http://purl.obolibrary.org/obo/UPHENO_0063571
+http://purl.obolibrary.org/obo/UBERON_0000995	http://purl.obolibrary.org/obo/UPHENO_0063600
+http://purl.obolibrary.org/obo/UBERON_0001153	http://purl.obolibrary.org/obo/UPHENO_0063564
+http://purl.obolibrary.org/obo/UBERON_0001043	http://purl.obolibrary.org/obo/UPHENO_0063603
+http://purl.obolibrary.org/obo/UBERON_0009972	http://purl.obolibrary.org/obo/UPHENO_0063589
+http://purl.obolibrary.org/obo/UBERON_0001981	http://purl.obolibrary.org/obo/UPHENO_0063573
+http://purl.obolibrary.org/obo/UBERON_0002135	http://purl.obolibrary.org/obo/UPHENO_0063605
+http://purl.obolibrary.org/obo/UBERON_0002146	http://purl.obolibrary.org/obo/UPHENO_0063591
+http://purl.obolibrary.org/obo/UBERON_0001155	http://purl.obolibrary.org/obo/UPHENO_0063617
+http://purl.obolibrary.org/obo/UBERON_0000166	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002134	http://purl.obolibrary.org/obo/UPHENO_0063606
+http://purl.obolibrary.org/obo/UBERON_0005928	http://purl.obolibrary.org/obo/UPHENO_0063592
+http://purl.obolibrary.org/obo/UBERON_0000996	http://purl.obolibrary.org/obo/UPHENO_0063593
diff --git a/src/curation/upheno-fillers/mp/atrophiedAnatomicalEntity.tsv b/src/curation/upheno-fillers/mp/atrophiedAnatomicalEntity.tsv
new file mode 100644
index 00000000..5d850a55
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/atrophiedAnatomicalEntity.tsv
@@ -0,0 +1,55 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0004187	http://purl.obolibrary.org/obo/UPHENO_0013914
+http://purl.obolibrary.org/obo/UBERON_0001630	http://purl.obolibrary.org/obo/UPHENO_0013920
+http://purl.obolibrary.org/obo/UBERON_0001872	http://purl.obolibrary.org/obo/UPHENO_0082996
+http://purl.obolibrary.org/obo/UBERON_0002369	http://purl.obolibrary.org/obo/UPHENO_0014002
+http://purl.obolibrary.org/obo/UBERON_0004103	http://purl.obolibrary.org/obo/UPHENO_0013922
+http://purl.obolibrary.org/obo/UBERON_0001231	http://purl.obolibrary.org/obo/UPHENO_0013924
+http://purl.obolibrary.org/obo/UBERON_0001871	http://purl.obolibrary.org/obo/UPHENO_0082997
+http://purl.obolibrary.org/obo/UBERON_0002124	http://purl.obolibrary.org/obo/UPHENO_0014005
+http://purl.obolibrary.org/obo/UBERON_0001232	http://purl.obolibrary.org/obo/UPHENO_0013927
+http://purl.obolibrary.org/obo/CL_0002064	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002123	http://purl.obolibrary.org/obo/UPHENO_0014007
+http://purl.obolibrary.org/obo/UBERON_0000017	http://purl.obolibrary.org/obo/UPHENO_0013931
+http://purl.obolibrary.org/obo/UBERON_0001228	http://purl.obolibrary.org/obo/UPHENO_0013932
+http://purl.obolibrary.org/obo/UBERON_0001821	http://purl.obolibrary.org/obo/UPHENO_0014013
+http://purl.obolibrary.org/obo/UBERON_0003889	http://purl.obolibrary.org/obo/UPHENO_0013934
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0013936
+http://purl.obolibrary.org/obo/UBERON_0004053	http://purl.obolibrary.org/obo/UPHENO_0013940
+http://purl.obolibrary.org/obo/CL_0000178	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002037	http://purl.obolibrary.org/obo/UPHENO_0013942
+http://purl.obolibrary.org/obo/UBERON_0000014	http://purl.obolibrary.org/obo/UPHENO_0013943
+http://purl.obolibrary.org/obo/UBERON_0001225	http://purl.obolibrary.org/obo/UPHENO_0013944
+http://purl.obolibrary.org/obo/UBERON_0002435	http://purl.obolibrary.org/obo/UPHENO_0078055
+http://purl.obolibrary.org/obo/UBERON_0001264	http://purl.obolibrary.org/obo/UPHENO_0014017
+http://purl.obolibrary.org/obo/UBERON_0002113	http://purl.obolibrary.org/obo/UPHENO_0014019
+http://purl.obolibrary.org/obo/UBERON_0001782	http://purl.obolibrary.org/obo/UPHENO_0014021
+http://purl.obolibrary.org/obo/UBERON_0001817	http://purl.obolibrary.org/obo/UPHENO_0014022
+http://purl.obolibrary.org/obo/UBERON_0000325	http://purl.obolibrary.org/obo/UPHENO_0014023
+http://purl.obolibrary.org/obo/UBERON_0001818	http://purl.obolibrary.org/obo/UPHENO_0014029
+http://purl.obolibrary.org/obo/UBERON_0001295	http://purl.obolibrary.org/obo/UPHENO_0013954
+http://purl.obolibrary.org/obo/CL_0000188	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001213	http://purl.obolibrary.org/obo/UPHENO_0013958
+http://purl.obolibrary.org/obo/UBERON_0001776	http://purl.obolibrary.org/obo/UPHENO_0014038
+http://purl.obolibrary.org/obo/UBERON_0002106	http://purl.obolibrary.org/obo/UPHENO_0014039
+http://purl.obolibrary.org/obo/UBERON_0001577	http://purl.obolibrary.org/obo/UPHENO_0013961
+http://purl.obolibrary.org/obo/UBERON_0002028	http://purl.obolibrary.org/obo/UPHENO_0013962
+http://purl.obolibrary.org/obo/UBERON_0001891	http://purl.obolibrary.org/obo/UPHENO_0014040
+http://purl.obolibrary.org/obo/UBERON_0001890	http://purl.obolibrary.org/obo/UPHENO_0014042
+http://purl.obolibrary.org/obo/UBERON_0000362	http://purl.obolibrary.org/obo/UPHENO_0013966
+http://purl.obolibrary.org/obo/UBERON_0001134	http://purl.obolibrary.org/obo/UPHENO_0014043
+http://purl.obolibrary.org/obo/UBERON_0001133	http://purl.obolibrary.org/obo/UPHENO_0014044
+http://purl.obolibrary.org/obo/UBERON_0000996	http://purl.obolibrary.org/obo/UPHENO_0013970
+http://purl.obolibrary.org/obo/UBERON_0000997	http://purl.obolibrary.org/obo/UPHENO_0013971
+http://purl.obolibrary.org/obo/UBERON_0001769	http://purl.obolibrary.org/obo/UPHENO_0014052
+http://purl.obolibrary.org/obo/UBERON_0000998	http://purl.obolibrary.org/obo/UPHENO_0013972
+http://purl.obolibrary.org/obo/UBERON_0000955	http://purl.obolibrary.org/obo/UPHENO_0014053
+http://purl.obolibrary.org/obo/UBERON_0002370	http://purl.obolibrary.org/obo/UPHENO_0013976
+http://purl.obolibrary.org/obo/UBERON_0000074	http://purl.obolibrary.org/obo/UPHENO_0013978
+http://purl.obolibrary.org/obo/UBERON_0000992	http://purl.obolibrary.org/obo/UPHENO_0013980
+http://purl.obolibrary.org/obo/UBERON_0001003	http://purl.obolibrary.org/obo/UPHENO_0014058
+http://purl.obolibrary.org/obo/UBERON_0000995	http://purl.obolibrary.org/obo/UPHENO_0013982
+http://purl.obolibrary.org/obo/UBERON_0000473	http://purl.obolibrary.org/obo/UPHENO_0013986
+http://purl.obolibrary.org/obo/UBERON_0001833	http://purl.obolibrary.org/obo/UPHENO_0013991
+http://purl.obolibrary.org/obo/UBERON_0000941	http://purl.obolibrary.org/obo/UPHENO_0014062
+http://purl.obolibrary.org/obo/UBERON_0000029	http://purl.obolibrary.org/obo/UPHENO_0080350
diff --git a/src/curation/upheno-fillers/mp/bifurcatedAnatomicalEntity.tsv b/src/curation/upheno-fillers/mp/bifurcatedAnatomicalEntity.tsv
new file mode 100644
index 00000000..cb5834dc
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/bifurcatedAnatomicalEntity.tsv
@@ -0,0 +1,8 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0055805
+http://purl.obolibrary.org/obo/UBERON_0002415	http://purl.obolibrary.org/obo/UPHENO_0055799
+http://purl.obolibrary.org/obo/UBERON_0002228	http://purl.obolibrary.org/obo/UPHENO_0055813
+http://purl.obolibrary.org/obo/UBERON_0000975	http://purl.obolibrary.org/obo/UPHENO_0055800
+http://purl.obolibrary.org/obo/UBERON_0001093	http://purl.obolibrary.org/obo/UPHENO_0055789
+http://purl.obolibrary.org/obo/UBERON_0001092	http://purl.obolibrary.org/obo/UPHENO_0055790
+http://purl.obolibrary.org/obo/UBERON_0005356	http://purl.obolibrary.org/obo/UPHENO_0055796
diff --git a/src/curation/upheno-fillers/mp/blisteredAnatomicalEntity.tsv b/src/curation/upheno-fillers/mp/blisteredAnatomicalEntity.tsv
new file mode 100644
index 00000000..76a73c9e
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/blisteredAnatomicalEntity.tsv
@@ -0,0 +1,3 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0011967
+http://purl.obolibrary.org/obo/UBERON_0003729	http://purl.obolibrary.org/obo/UPHENO_0011969
diff --git a/src/curation/upheno-fillers/mp/brokenAnatomicalEntity.tsv b/src/curation/upheno-fillers/mp/brokenAnatomicalEntity.tsv
new file mode 100644
index 00000000..63d6248e
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/brokenAnatomicalEntity.tsv
@@ -0,0 +1,8 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0081401
+http://purl.obolibrary.org/obo/UBERON_0001804	http://purl.obolibrary.org/obo/UPHENO_0081402
+http://purl.obolibrary.org/obo/UBERON_0002228	http://purl.obolibrary.org/obo/UPHENO_0081403
+http://purl.obolibrary.org/obo/UBERON_0000019	http://purl.obolibrary.org/obo/UPHENO_0081404
+http://purl.obolibrary.org/obo/UBERON_0000981	http://purl.obolibrary.org/obo/UPHENO_0081405
+http://purl.obolibrary.org/obo/UBERON_0003107	http://purl.obolibrary.org/obo/UPHENO_0081406
+http://purl.obolibrary.org/obo/UBERON_0000995	http://purl.obolibrary.org/obo/UPHENO_0081407
diff --git a/src/curation/upheno-fillers/mp/calcifiedAnatomicalEntity.tsv b/src/curation/upheno-fillers/mp/calcifiedAnatomicalEntity.tsv
new file mode 100644
index 00000000..2d0cb1df
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/calcifiedAnatomicalEntity.tsv
@@ -0,0 +1,28 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0005991	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0005990	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0000982	http://purl.obolibrary.org/obo/UPHENO_0067758
+http://purl.obolibrary.org/obo/UBERON_0001630	http://purl.obolibrary.org/obo/UPHENO_0067759
+http://purl.obolibrary.org/obo/UBERON_0005996	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0005995	http://purl.obolibrary.org/obo/UPHENO_0084188
+http://purl.obolibrary.org/obo/UBERON_0000043	http://purl.obolibrary.org/obo/UPHENO_0067798
+http://purl.obolibrary.org/obo/UBERON_0002146	http://purl.obolibrary.org/obo/UPHENO_0067799
+http://purl.obolibrary.org/obo/UBERON_0001508	http://purl.obolibrary.org/obo/UPHENO_0067763
+http://purl.obolibrary.org/obo/UBERON_0000019	http://purl.obolibrary.org/obo/UPHENO_0067764
+http://purl.obolibrary.org/obo/UBERON_0000955	http://purl.obolibrary.org/obo/UPHENO_0067802
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0067765
+http://purl.obolibrary.org/obo/UBERON_0002137	http://purl.obolibrary.org/obo/UPHENO_0067809
+http://purl.obolibrary.org/obo/UBERON_0003701	http://purl.obolibrary.org/obo/UPHENO_0067811
+http://purl.obolibrary.org/obo/UBERON_0000014	http://purl.obolibrary.org/obo/UPHENO_0067773
+http://purl.obolibrary.org/obo/UBERON_0001066	http://purl.obolibrary.org/obo/UPHENO_0067775
+http://purl.obolibrary.org/obo/UBERON_0001264	http://purl.obolibrary.org/obo/UPHENO_0067776
+http://purl.obolibrary.org/obo/UBERON_0001187	http://purl.obolibrary.org/obo/UPHENO_0082495
+http://purl.obolibrary.org/obo/UBERON_0002135	http://purl.obolibrary.org/obo/UPHENO_0067818
+http://purl.obolibrary.org/obo/UBERON_0002113	http://purl.obolibrary.org/obo/UPHENO_0067779
+http://purl.obolibrary.org/obo/UBERON_0002299	http://purl.obolibrary.org/obo/UPHENO_0067819
+http://purl.obolibrary.org/obo/UBERON_0002134	http://purl.obolibrary.org/obo/UPHENO_0067820
+http://purl.obolibrary.org/obo/UBERON_0000947	http://purl.obolibrary.org/obo/UPHENO_0067822
+http://purl.obolibrary.org/obo/UBERON_0002349	http://purl.obolibrary.org/obo/UPHENO_0082496
+http://purl.obolibrary.org/obo/UBERON_0001637	http://purl.obolibrary.org/obo/UPHENO_0067824
+http://purl.obolibrary.org/obo/UBERON_0000966	http://purl.obolibrary.org/obo/UPHENO_0067783
+http://purl.obolibrary.org/obo/UBERON_0001515	http://purl.obolibrary.org/obo/UPHENO_0067825
diff --git a/src/curation/upheno-fillers/mp/collapsedAnatomicalEntity.tsv b/src/curation/upheno-fillers/mp/collapsedAnatomicalEntity.tsv
new file mode 100644
index 00000000..12224226
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/collapsedAnatomicalEntity.tsv
@@ -0,0 +1,4 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0004086	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002281	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/mp/cystInLocation.tsv b/src/curation/upheno-fillers/mp/cystInLocation.tsv
new file mode 100644
index 00000000..b2058bd0
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/cystInLocation.tsv
@@ -0,0 +1,39 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0002081	http://purl.obolibrary.org/obo/UPHENO_0081066
+http://purl.obolibrary.org/obo/UBERON_0002048	http://purl.obolibrary.org/obo/UPHENO_0083398
+http://purl.obolibrary.org/obo/UBERON_0002367	http://purl.obolibrary.org/obo/UPHENO_0081067
+http://purl.obolibrary.org/obo/UBERON_0002369	http://purl.obolibrary.org/obo/UPHENO_0083399
+http://purl.obolibrary.org/obo/UBERON_0002067	http://purl.obolibrary.org/obo/UPHENO_0083400
+http://purl.obolibrary.org/obo/UBERON_0000362	http://purl.obolibrary.org/obo/UPHENO_0083401
+http://purl.obolibrary.org/obo/UBERON_0002366	http://purl.obolibrary.org/obo/UPHENO_0083402
+http://purl.obolibrary.org/obo/UBERON_0000341	http://purl.obolibrary.org/obo/UPHENO_0083403
+http://purl.obolibrary.org/obo/UBERON_0001255	http://purl.obolibrary.org/obo/UPHENO_0081069
+http://purl.obolibrary.org/obo/UBERON_0002046	http://purl.obolibrary.org/obo/UPHENO_0083404
+http://purl.obolibrary.org/obo/UBERON_0001305	http://purl.obolibrary.org/obo/UPHENO_0083405
+http://purl.obolibrary.org/obo/UBERON_0000996	http://purl.obolibrary.org/obo/UPHENO_0083406
+http://purl.obolibrary.org/obo/UBERON_0000997	http://purl.obolibrary.org/obo/UPHENO_0083407
+http://purl.obolibrary.org/obo/UBERON_0003702	http://purl.obolibrary.org/obo/UPHENO_0083408
+http://purl.obolibrary.org/obo/UBERON_0001846	http://purl.obolibrary.org/obo/UPHENO_0083409
+http://purl.obolibrary.org/obo/UBERON_0005291	http://purl.obolibrary.org/obo/UPHENO_0083410
+http://purl.obolibrary.org/obo/UBERON_0011595	http://purl.obolibrary.org/obo/UPHENO_0083411
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0081065
+http://purl.obolibrary.org/obo/UBERON_0002370	http://purl.obolibrary.org/obo/UPHENO_0083412
+http://purl.obolibrary.org/obo/UBERON_0002394	http://purl.obolibrary.org/obo/UPHENO_0083413
+http://purl.obolibrary.org/obo/UBERON_0000074	http://purl.obolibrary.org/obo/UPHENO_0083414
+http://purl.obolibrary.org/obo/UBERON_0001301	http://purl.obolibrary.org/obo/UPHENO_0083415
+http://purl.obolibrary.org/obo/UBERON_0000992	http://purl.obolibrary.org/obo/UPHENO_0083416
+http://purl.obolibrary.org/obo/UBERON_0001003	http://purl.obolibrary.org/obo/UPHENO_0083417
+http://purl.obolibrary.org/obo/UBERON_0000014	http://purl.obolibrary.org/obo/UPHENO_0083418
+http://purl.obolibrary.org/obo/UBERON_0001225	http://purl.obolibrary.org/obo/UPHENO_0083419
+http://purl.obolibrary.org/obo/UBERON_0005942	http://purl.obolibrary.org/obo/UPHENO_0083420
+http://purl.obolibrary.org/obo/UBERON_0000995	http://purl.obolibrary.org/obo/UPHENO_0081068
+http://purl.obolibrary.org/obo/UBERON_0002397	http://purl.obolibrary.org/obo/UPHENO_0083421
+http://purl.obolibrary.org/obo/UBERON_0001264	http://purl.obolibrary.org/obo/UPHENO_0083422
+http://purl.obolibrary.org/obo/UBERON_0002113	http://purl.obolibrary.org/obo/UPHENO_0083423
+http://purl.obolibrary.org/obo/UBERON_0001684	http://purl.obolibrary.org/obo/UPHENO_0083424
+http://purl.obolibrary.org/obo/UBERON_0000945	http://purl.obolibrary.org/obo/UPHENO_0083425
+http://purl.obolibrary.org/obo/UBERON_0000468	http://purl.obolibrary.org/obo/UPHENO_0083426
+http://purl.obolibrary.org/obo/UBERON_0001833	http://purl.obolibrary.org/obo/UPHENO_0083427
+http://purl.obolibrary.org/obo/UBERON_0002107	http://purl.obolibrary.org/obo/UPHENO_0083428
+http://purl.obolibrary.org/obo/UBERON_0009917	http://purl.obolibrary.org/obo/UPHENO_0083429
+http://purl.obolibrary.org/obo/UBERON_0001818	http://purl.obolibrary.org/obo/UPHENO_0083430
diff --git a/src/curation/upheno-fillers/mp/delaminatedAnatomicalEntity.tsv b/src/curation/upheno-fillers/mp/delaminatedAnatomicalEntity.tsv
new file mode 100644
index 00000000..d751462c
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/delaminatedAnatomicalEntity.tsv
@@ -0,0 +1,6 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0000956	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002979	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002956	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001752	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/mp/dislocatedAnatomicalEntity.tsv b/src/curation/upheno-fillers/mp/dislocatedAnatomicalEntity.tsv
new file mode 100644
index 00000000..babc452e
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/dislocatedAnatomicalEntity.tsv
@@ -0,0 +1,9 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001491	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001490	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0000982	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002446	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0000220	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001486	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001012	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/mp/disorganizedAnatomicalEntity.tsv b/src/curation/upheno-fillers/mp/disorganizedAnatomicalEntity.tsv
new file mode 100644
index 00000000..a1524f6e
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/disorganizedAnatomicalEntity.tsv
@@ -0,0 +1,30 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0007798	http://purl.obolibrary.org/obo/UPHENO_0084688
+http://purl.obolibrary.org/obo/UBERON_0010415	http://purl.obolibrary.org/obo/UPHENO_0084689
+http://purl.obolibrary.org/obo/CL_0002561	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001790	http://purl.obolibrary.org/obo/UPHENO_0084690
+http://purl.obolibrary.org/obo/UBERON_0005297	http://purl.obolibrary.org/obo/UPHENO_0084691
+http://purl.obolibrary.org/obo/UBERON_0001897	http://purl.obolibrary.org/obo/UPHENO_0084693
+http://purl.obolibrary.org/obo/GO_0001917	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001792	http://purl.obolibrary.org/obo/UPHENO_0084695
+http://purl.obolibrary.org/obo/UBERON_0001791	http://purl.obolibrary.org/obo/UPHENO_0084696
+http://purl.obolibrary.org/obo/CL_0000182	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001772	http://purl.obolibrary.org/obo/UPHENO_0084697
+http://purl.obolibrary.org/obo/UBERON_0000044	http://purl.obolibrary.org/obo/UPHENO_0084698
+http://purl.obolibrary.org/obo/CL_0002560	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001199	http://purl.obolibrary.org/obo/UPHENO_0084699
+http://purl.obolibrary.org/obo/UBERON_0003946	http://purl.obolibrary.org/obo/UPHENO_0084701
+http://purl.obolibrary.org/obo/UBERON_0001789	http://purl.obolibrary.org/obo/UPHENO_0084702
+http://purl.obolibrary.org/obo/GO_0001750	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002516	http://purl.obolibrary.org/obo/UPHENO_0084704
+http://purl.obolibrary.org/obo/UBERON_0005291	http://purl.obolibrary.org/obo/UPHENO_0084705
+http://purl.obolibrary.org/obo/CL_0000746	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0084685
+http://purl.obolibrary.org/obo/UBERON_0005343	http://purl.obolibrary.org/obo/UPHENO_0084686
+http://purl.obolibrary.org/obo/UBERON_0002074	http://purl.obolibrary.org/obo/UPHENO_0084687
+http://purl.obolibrary.org/obo/GO_0030061	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0002495	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0010402	http://purl.obolibrary.org/obo/UPHENO_0084692
+http://purl.obolibrary.org/obo/UBERON_0000478	http://purl.obolibrary.org/obo/UPHENO_0084694
+http://purl.obolibrary.org/obo/UBERON_0000006	http://purl.obolibrary.org/obo/UPHENO_0084700
+http://purl.obolibrary.org/obo/UBERON_0002349	http://purl.obolibrary.org/obo/UPHENO_0084703
diff --git a/src/curation/upheno-fillers/mp/dysplasticAnatomicalEntity.tsv b/src/curation/upheno-fillers/mp/dysplasticAnatomicalEntity.tsv
new file mode 100644
index 00000000..25d42f33
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/dysplasticAnatomicalEntity.tsv
@@ -0,0 +1,9 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0047299
+http://purl.obolibrary.org/obo/UBERON_0000428	http://purl.obolibrary.org/obo/UPHENO_0047330
+http://purl.obolibrary.org/obo/UBERON_0003973	http://purl.obolibrary.org/obo/UPHENO_0047291
+http://purl.obolibrary.org/obo/UBERON_0003971	http://purl.obolibrary.org/obo/UPHENO_0047294
+http://purl.obolibrary.org/obo/UBERON_0004346	http://purl.obolibrary.org/obo/UPHENO_0047295
+http://purl.obolibrary.org/obo/UBERON_0003972	http://purl.obolibrary.org/obo/UPHENO_0047296
+http://purl.obolibrary.org/obo/UBERON_0002222	http://purl.obolibrary.org/obo/UPHENO_0047320
+http://purl.obolibrary.org/obo/UBERON_0003970	http://purl.obolibrary.org/obo/UPHENO_0047298
diff --git a/src/curation/upheno-fillers/mp/edematousAnatomicalEntity.tsv b/src/curation/upheno-fillers/mp/edematousAnatomicalEntity.tsv
new file mode 100644
index 00000000..a572f0cf
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/edematousAnatomicalEntity.tsv
@@ -0,0 +1,19 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0082498
+http://purl.obolibrary.org/obo/UBERON_0000160	http://purl.obolibrary.org/obo/UPHENO_0082499
+http://purl.obolibrary.org/obo/UBERON_0002240	http://purl.obolibrary.org/obo/UPHENO_0082500
+http://purl.obolibrary.org/obo/UBERON_0001074	http://purl.obolibrary.org/obo/UPHENO_0082501
+http://purl.obolibrary.org/obo/UBERON_0002072	http://purl.obolibrary.org/obo/UPHENO_0082502
+http://purl.obolibrary.org/obo/UBERON_0035619	http://purl.obolibrary.org/obo/UPHENO_0082503
+http://purl.obolibrary.org/obo/UBERON_0000982	http://purl.obolibrary.org/obo/UPHENO_0082505
+http://purl.obolibrary.org/obo/UBERON_0002048	http://purl.obolibrary.org/obo/UPHENO_0082506
+http://purl.obolibrary.org/obo/UBERON_0000014	http://purl.obolibrary.org/obo/UPHENO_0082507
+http://purl.obolibrary.org/obo/UBERON_0000026	http://purl.obolibrary.org/obo/UPHENO_0082508
+http://purl.obolibrary.org/obo/UBERON_0002299	http://purl.obolibrary.org/obo/UPHENO_0082509
+http://purl.obolibrary.org/obo/UBERON_0001811	http://purl.obolibrary.org/obo/UPHENO_0082510
+http://purl.obolibrary.org/obo/UBERON_0000941	http://purl.obolibrary.org/obo/UPHENO_0082511
+http://purl.obolibrary.org/obo/UBERON_0001711	http://purl.obolibrary.org/obo/UPHENO_0082512
+http://purl.obolibrary.org/obo/UBERON_0000955	http://purl.obolibrary.org/obo/UPHENO_0082513
+http://purl.obolibrary.org/obo/UBERON_0000922	http://purl.obolibrary.org/obo/UPHENO_0082514
+http://purl.obolibrary.org/obo/UBERON_0004090	http://purl.obolibrary.org/obo/UPHENO_0082515
+http://purl.obolibrary.org/obo/UBERON_0012477	http://purl.obolibrary.org/obo/UPHENO_0082516
diff --git a/src/curation/upheno-fillers/mp/exsertedAnatomicalEntity.tsv b/src/curation/upheno-fillers/mp/exsertedAnatomicalEntity.tsv
new file mode 100644
index 00000000..d50105d0
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/exsertedAnatomicalEntity.tsv
@@ -0,0 +1,9 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0000989	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001847	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001052	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001723	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001711	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0010230	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001255	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/mp/fibroticAnatomicalEntity.tsv b/src/curation/upheno-fillers/mp/fibroticAnatomicalEntity.tsv
new file mode 100644
index 00000000..d9d76948
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/fibroticAnatomicalEntity.tsv
@@ -0,0 +1,28 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0000160	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001295	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002048	http://purl.obolibrary.org/obo/UPHENO_0076299
+http://purl.obolibrary.org/obo/UBERON_0002106	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0005215	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001134	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001255	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0076294
+http://purl.obolibrary.org/obo/UBERON_0002371	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002370	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0011898	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0000074	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001301	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0000992	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0000014	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0000114	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0003126	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0000995	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001264	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001043	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002113	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0000473	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0000945	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0000948	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002107	http://purl.obolibrary.org/obo/UPHENO_0076297
+http://purl.obolibrary.org/obo/UBERON_0000966	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0014930	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/mp/foldedAnatomicalEntity.tsv b/src/curation/upheno-fillers/mp/foldedAnatomicalEntity.tsv
new file mode 100644
index 00000000..03e649a7
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/foldedAnatomicalEntity.tsv
@@ -0,0 +1,3 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002488	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/mp/herniatedAnatomicalEntity.tsv b/src/curation/upheno-fillers/mp/herniatedAnatomicalEntity.tsv
new file mode 100644
index 00000000..ff2a04d4
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/herniatedAnatomicalEntity.tsv
@@ -0,0 +1,8 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0000160	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002107	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0000998	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001103	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002331	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0003697	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/mp/hyperplasticAnatomicalEntity.tsv b/src/curation/upheno-fillers/mp/hyperplasticAnatomicalEntity.tsv
new file mode 100644
index 00000000..16cde1c4
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/hyperplasticAnatomicalEntity.tsv
@@ -0,0 +1,98 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0004187	http://purl.obolibrary.org/obo/UPHENO_0083508
+http://purl.obolibrary.org/obo/UBERON_0011947	http://purl.obolibrary.org/obo/UPHENO_0083509
+http://purl.obolibrary.org/obo/UBERON_0001235	http://purl.obolibrary.org/obo/UPHENO_0083510
+http://purl.obolibrary.org/obo/UBERON_0000388	http://purl.obolibrary.org/obo/UPHENO_0083511
+http://purl.obolibrary.org/obo/UBERON_0002048	http://purl.obolibrary.org/obo/UPHENO_0083513
+http://purl.obolibrary.org/obo/UBERON_0007615	http://purl.obolibrary.org/obo/UPHENO_0083516
+http://purl.obolibrary.org/obo/UBERON_0001236	http://purl.obolibrary.org/obo/UPHENO_0083518
+http://purl.obolibrary.org/obo/UBERON_0001473	http://purl.obolibrary.org/obo/UPHENO_0083519
+http://purl.obolibrary.org/obo/UBERON_0001199	http://purl.obolibrary.org/obo/UPHENO_0083523
+http://purl.obolibrary.org/obo/UBERON_0002046	http://purl.obolibrary.org/obo/UPHENO_0083525
+http://purl.obolibrary.org/obo/UBERON_0000017	http://purl.obolibrary.org/obo/UPHENO_0084410
+http://purl.obolibrary.org/obo/UBERON_0001744	http://purl.obolibrary.org/obo/UPHENO_0083527
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0083530
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diff --git a/src/curation/upheno-fillers/mp/hypertrophicAnatomicalEntity.tsv b/src/curation/upheno-fillers/mp/hypertrophicAnatomicalEntity.tsv
new file mode 100644
index 00000000..9106492c
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/hypertrophicAnatomicalEntity.tsv
@@ -0,0 +1,29 @@
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diff --git a/src/curation/upheno-fillers/mp/hypoplasticAnatomicalEntity.tsv b/src/curation/upheno-fillers/mp/hypoplasticAnatomicalEntity.tsv
new file mode 100644
index 00000000..9385867d
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/hypoplasticAnatomicalEntity.tsv
@@ -0,0 +1,204 @@
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+http://purl.obolibrary.org/obo/UBERON_0002028	http://purl.obolibrary.org/obo/UPHENO_0081125
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+http://purl.obolibrary.org/obo/UBERON_0001847	http://purl.obolibrary.org/obo/UPHENO_0081134
+http://purl.obolibrary.org/obo/UBERON_0001723	http://purl.obolibrary.org/obo/UPHENO_0081135
+http://purl.obolibrary.org/obo/UBERON_0000996	http://purl.obolibrary.org/obo/UPHENO_0081136
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+http://purl.obolibrary.org/obo/UBERON_0000998	http://purl.obolibrary.org/obo/UPHENO_0081140
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+http://purl.obolibrary.org/obo/UBERON_0002494	http://purl.obolibrary.org/obo/UPHENO_0081145
+http://purl.obolibrary.org/obo/UBERON_0001042	http://purl.obolibrary.org/obo/UPHENO_0081146
+http://purl.obolibrary.org/obo/UBERON_0002137	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0000992	http://purl.obolibrary.org/obo/UPHENO_0081148
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+http://purl.obolibrary.org/obo/UBERON_0003107	http://purl.obolibrary.org/obo/UPHENO_0081150
+http://purl.obolibrary.org/obo/UBERON_0000995	http://purl.obolibrary.org/obo/UPHENO_0081155
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+http://purl.obolibrary.org/obo/UBERON_0001043	http://purl.obolibrary.org/obo/UPHENO_0081159
+http://purl.obolibrary.org/obo/UBERON_0002374	http://purl.obolibrary.org/obo/UPHENO_0081160
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+http://purl.obolibrary.org/obo/UBERON_0001711	http://purl.obolibrary.org/obo/UPHENO_0081167
+http://purl.obolibrary.org/obo/UBERON_0006849	http://purl.obolibrary.org/obo/UPHENO_0081169
+http://purl.obolibrary.org/obo/UBERON_0004660	http://purl.obolibrary.org/obo/UPHENO_0081170
+http://purl.obolibrary.org/obo/UBERON_0005871	http://purl.obolibrary.org/obo/UPHENO_0081171
+http://purl.obolibrary.org/obo/UBERON_0002367	http://purl.obolibrary.org/obo/UPHENO_0081177
+http://purl.obolibrary.org/obo/UBERON_0002369	http://purl.obolibrary.org/obo/UPHENO_0081179
+http://purl.obolibrary.org/obo/UBERON_0005876	http://purl.obolibrary.org/obo/UPHENO_0081180
+http://purl.obolibrary.org/obo/UBERON_0001275	http://purl.obolibrary.org/obo/UPHENO_0081182
+http://purl.obolibrary.org/obo/UBERON_0006721	http://purl.obolibrary.org/obo/UPHENO_0081183
+http://purl.obolibrary.org/obo/UBERON_0001274	http://purl.obolibrary.org/obo/UPHENO_0081184
+http://purl.obolibrary.org/obo/UBERON_0002366	http://purl.obolibrary.org/obo/UPHENO_0081187
+http://purl.obolibrary.org/obo/UBERON_0001277	http://purl.obolibrary.org/obo/UPHENO_0084436
+http://purl.obolibrary.org/obo/UBERON_0002124	http://purl.obolibrary.org/obo/UPHENO_0081188
+http://purl.obolibrary.org/obo/UBERON_0002244	http://purl.obolibrary.org/obo/UPHENO_0081189
+http://purl.obolibrary.org/obo/UBERON_0002123	http://purl.obolibrary.org/obo/UPHENO_0081190
+http://purl.obolibrary.org/obo/UBERON_0001706	http://purl.obolibrary.org/obo/UPHENO_0081191
+http://purl.obolibrary.org/obo/UBERON_0001821	http://purl.obolibrary.org/obo/UPHENO_0081192
+http://purl.obolibrary.org/obo/UBERON_0000975	http://purl.obolibrary.org/obo/UPHENO_0081193
+http://purl.obolibrary.org/obo/UBERON_0001823	http://purl.obolibrary.org/obo/UPHENO_0081338
+http://purl.obolibrary.org/obo/UBERON_0002351	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0004657	http://purl.obolibrary.org/obo/UPHENO_0081199
+http://purl.obolibrary.org/obo/UBERON_0005868	http://purl.obolibrary.org/obo/UPHENO_0081200
+http://purl.obolibrary.org/obo/UBERON_0005867	http://purl.obolibrary.org/obo/UPHENO_0081202
+http://purl.obolibrary.org/obo/UBERON_0001264	http://purl.obolibrary.org/obo/UPHENO_0081205
+http://purl.obolibrary.org/obo/UBERON_0002352	http://purl.obolibrary.org/obo/UPHENO_0081208
+http://purl.obolibrary.org/obo/UBERON_0001263	http://purl.obolibrary.org/obo/UPHENO_0081209
+http://purl.obolibrary.org/obo/UBERON_0002113	http://purl.obolibrary.org/obo/UPHENO_0081210
+http://purl.obolibrary.org/obo/UBERON_0000056	http://purl.obolibrary.org/obo/UPHENO_0081213
+http://purl.obolibrary.org/obo/UBERON_0001817	http://purl.obolibrary.org/obo/UPHENO_0081215
+http://purl.obolibrary.org/obo/UBERON_0002229	http://purl.obolibrary.org/obo/UPHENO_0081217
+http://purl.obolibrary.org/obo/UBERON_0005619	http://purl.obolibrary.org/obo/UPHENO_0081218
+http://purl.obolibrary.org/obo/UBERON_0002107	http://purl.obolibrary.org/obo/UPHENO_0081219
+http://purl.obolibrary.org/obo/UBERON_0002349	http://purl.obolibrary.org/obo/UPHENO_0081220
+http://purl.obolibrary.org/obo/UBERON_0000966	http://purl.obolibrary.org/obo/UPHENO_0081222
+http://purl.obolibrary.org/obo/UBERON_0001818	http://purl.obolibrary.org/obo/UPHENO_0081223
+http://purl.obolibrary.org/obo/UBERON_0004089	http://purl.obolibrary.org/obo/UPHENO_0081227
+http://purl.obolibrary.org/obo/UBERON_0005294	http://purl.obolibrary.org/obo/UPHENO_0081229
+http://purl.obolibrary.org/obo/UBERON_0002106	http://purl.obolibrary.org/obo/UPHENO_0081233
+http://purl.obolibrary.org/obo/UBERON_0001132	http://purl.obolibrary.org/obo/UPHENO_0081238
+http://purl.obolibrary.org/obo/UBERON_0000044	http://purl.obolibrary.org/obo/UPHENO_0081241
+http://purl.obolibrary.org/obo/UBERON_0001134	http://purl.obolibrary.org/obo/UPHENO_0081242
+http://purl.obolibrary.org/obo/UBERON_0001255	http://purl.obolibrary.org/obo/UPHENO_0081244
+http://purl.obolibrary.org/obo/UBERON_0001496	http://purl.obolibrary.org/obo/UPHENO_0081245
+http://purl.obolibrary.org/obo/UBERON_0002218	http://purl.obolibrary.org/obo/UPHENO_0081248
+http://purl.obolibrary.org/obo/UBERON_0018242	http://purl.obolibrary.org/obo/UPHENO_0081249
+http://purl.obolibrary.org/obo/UBERON_0005969	http://purl.obolibrary.org/obo/UPHENO_0081250
+http://purl.obolibrary.org/obo/UBERON_0005967	http://purl.obolibrary.org/obo/UPHENO_0081253
+http://purl.obolibrary.org/obo/UBERON_0001000	http://purl.obolibrary.org/obo/UPHENO_0081256
+http://purl.obolibrary.org/obo/UBERON_0000395	http://purl.obolibrary.org/obo/UPHENO_0081257
+http://purl.obolibrary.org/obo/UBERON_0002333	http://purl.obolibrary.org/obo/UPHENO_0081258
+http://purl.obolibrary.org/obo/UBERON_0000945	http://purl.obolibrary.org/obo/UPHENO_0081259
+http://purl.obolibrary.org/obo/UBERON_0000947	http://purl.obolibrary.org/obo/UPHENO_0081261
+http://purl.obolibrary.org/obo/UBERON_0000948	http://purl.obolibrary.org/obo/UPHENO_0081262
+http://purl.obolibrary.org/obo/UBERON_0000941	http://purl.obolibrary.org/obo/UPHENO_0081264
+http://purl.obolibrary.org/obo/UBERON_0000029	http://purl.obolibrary.org/obo/UPHENO_0081265
+http://purl.obolibrary.org/obo/UBERON_0001911	http://purl.obolibrary.org/obo/UPHENO_0081266
diff --git a/src/curation/upheno-fillers/mp/malformedAnatomicalEntity.tsv b/src/curation/upheno-fillers/mp/malformedAnatomicalEntity.tsv
new file mode 100644
index 00000000..140d9011
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/malformedAnatomicalEntity.tsv
@@ -0,0 +1,3 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0071309
+http://purl.obolibrary.org/obo/UBERON_0000019	http://purl.obolibrary.org/obo/UPHENO_0071313
diff --git a/src/curation/upheno-fillers/mp/malformedAnatomicalEntityByType.tsv b/src/curation/upheno-fillers/mp/malformedAnatomicalEntityByType.tsv
new file mode 100644
index 00000000..cf7b23b0
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/malformedAnatomicalEntityByType.tsv
@@ -0,0 +1 @@
+anatomical_entity	malformed	defined_class
diff --git a/src/curation/upheno-fillers/mp/mislocalisedAnatomicalEntity.tsv b/src/curation/upheno-fillers/mp/mislocalisedAnatomicalEntity.tsv
new file mode 100644
index 00000000..3ac03913
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/mislocalisedAnatomicalEntity.tsv
@@ -0,0 +1,38 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/CL_0000121	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0000084	http://purl.obolibrary.org/obo/UPHENO_0053605
+http://purl.obolibrary.org/obo/CL_0000540	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000148	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002544	http://purl.obolibrary.org/obo/UPHENO_0053614
+http://purl.obolibrary.org/obo/UBERON_0002106	http://purl.obolibrary.org/obo/UPHENO_0053616
+http://purl.obolibrary.org/obo/UBERON_0001897	http://purl.obolibrary.org/obo/UPHENO_0053617
+http://purl.obolibrary.org/obo/UBERON_0002369	http://purl.obolibrary.org/obo/UPHENO_0053568
+http://purl.obolibrary.org/obo/UBERON_0004766	http://purl.obolibrary.org/obo/UPHENO_0053618
+http://purl.obolibrary.org/obo/UBERON_0001132	http://purl.obolibrary.org/obo/UPHENO_0053620
+http://purl.obolibrary.org/obo/CL_0001031	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001134	http://purl.obolibrary.org/obo/UPHENO_0053623
+http://purl.obolibrary.org/obo/UBERON_0001474	http://purl.obolibrary.org/obo/UPHENO_0053573
+http://purl.obolibrary.org/obo/CL_0002064	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002046	http://purl.obolibrary.org/obo/UPHENO_0053576
+http://purl.obolibrary.org/obo/UBERON_0002418	http://purl.obolibrary.org/obo/UPHENO_0053628
+http://purl.obolibrary.org/obo/UBERON_0002539	http://purl.obolibrary.org/obo/UPHENO_0053631
+http://purl.obolibrary.org/obo/CL_0000644	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000700	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0053580
+http://purl.obolibrary.org/obo/UBERON_0002030	http://purl.obolibrary.org/obo/UPHENO_0053581
+http://purl.obolibrary.org/obo/UBERON_0002370	http://purl.obolibrary.org/obo/UPHENO_0053635
+http://purl.obolibrary.org/obo/UBERON_0002196	http://purl.obolibrary.org/obo/UPHENO_0053583
+http://purl.obolibrary.org/obo/CL_0000695	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000178	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000510	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_1001571	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0000992	http://purl.obolibrary.org/obo/UPHENO_0053640
+http://purl.obolibrary.org/obo/UBERON_0001264	http://purl.obolibrary.org/obo/UPHENO_0053585
+http://purl.obolibrary.org/obo/UBERON_0002198	http://purl.obolibrary.org/obo/UPHENO_0053586
+http://purl.obolibrary.org/obo/UBERON_0002113	http://purl.obolibrary.org/obo/UPHENO_0053588
+http://purl.obolibrary.org/obo/UBERON_0000473	http://purl.obolibrary.org/obo/UPHENO_0053644
+http://purl.obolibrary.org/obo/UBERON_0000056	http://purl.obolibrary.org/obo/UPHENO_0053591
+http://purl.obolibrary.org/obo/GO_0002177	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0000007	http://purl.obolibrary.org/obo/UPHENO_0053592
+http://purl.obolibrary.org/obo/UBERON_0001911	http://purl.obolibrary.org/obo/UPHENO_0053648
+http://purl.obolibrary.org/obo/CL_0000216	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/mp/mislocalisedAnatomicalEntityInLocation.tsv b/src/curation/upheno-fillers/mp/mislocalisedAnatomicalEntityInLocation.tsv
new file mode 100644
index 00000000..0619c9c3
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/mislocalisedAnatomicalEntityInLocation.tsv
@@ -0,0 +1,3 @@
+anatomical_entity	location	defined_class
+http://purl.obolibrary.org/obo/CL_0000598	http://purl.obolibrary.org/obo/UBERON_0000956	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0000956	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/mp/necroticAnatomicalEntity.tsv b/src/curation/upheno-fillers/mp/necroticAnatomicalEntity.tsv
new file mode 100644
index 00000000..4834792b
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/necroticAnatomicalEntity.tsv
@@ -0,0 +1,28 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0002481	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0005253	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001691	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/CL_0000188	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002048	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001754	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0008266	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001231	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0003972	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001013	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001134	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001133	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001155	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001987	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002415	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0005291	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0081698
+http://purl.obolibrary.org/obo/UBERON_0001003	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0000115	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001264	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001285	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002113	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0000945	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001817	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002107	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0000029	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002349	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/mp/non-functionalAnatomicalEntity.tsv b/src/curation/upheno-fillers/mp/non-functionalAnatomicalEntity.tsv
new file mode 100644
index 00000000..2050afa0
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/non-functionalAnatomicalEntity.tsv
@@ -0,0 +1,6 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001711	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002107	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001004	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002113	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/mp/obstructedAnatomicalEntity.tsv b/src/curation/upheno-fillers/mp/obstructedAnatomicalEntity.tsv
new file mode 100644
index 00000000..a71e2a15
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/obstructedAnatomicalEntity.tsv
@@ -0,0 +1,16 @@
+anatomical_space	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001638	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001707	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0003959	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001508	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001637	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0000160	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002392	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001620	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0000057	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0003126	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0009972	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0009973	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001255	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0000056	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/mp/paralysedAnatomicalEntity.tsv b/src/curation/upheno-fillers/mp/paralysedAnatomicalEntity.tsv
new file mode 100644
index 00000000..34da10de
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/paralysedAnatomicalEntity.tsv
@@ -0,0 +1,9 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0081700
+http://purl.obolibrary.org/obo/UBERON_0001601	http://purl.obolibrary.org/obo/UPHENO_0081701
+http://purl.obolibrary.org/obo/UBERON_0000475	http://purl.obolibrary.org/obo/UPHENO_0081702
+http://purl.obolibrary.org/obo/UBERON_0001577	http://purl.obolibrary.org/obo/UPHENO_0081703
+http://purl.obolibrary.org/obo/UBERON_0003663	http://purl.obolibrary.org/obo/UPHENO_0081704
+http://purl.obolibrary.org/obo/UBERON_0003661	http://purl.obolibrary.org/obo/UPHENO_0081705
+http://purl.obolibrary.org/obo/UBERON_0003662	http://purl.obolibrary.org/obo/UPHENO_0081706
+http://purl.obolibrary.org/obo/UBERON_0006323	http://purl.obolibrary.org/obo/UPHENO_0081707
diff --git a/src/curation/upheno-fillers/mp/perforateAnatomicalEntity.tsv b/src/curation/upheno-fillers/mp/perforateAnatomicalEntity.tsv
new file mode 100644
index 00000000..e705cbab
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/perforateAnatomicalEntity.tsv
@@ -0,0 +1,10 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002085	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0000209	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0006430	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0000964	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0006849	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0006428	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001676	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002364	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/mp/prematureClosureOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/mp/prematureClosureOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..30858c71
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/prematureClosureOfAnatomicalEntity.tsv
@@ -0,0 +1,15 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0084631
+http://purl.obolibrary.org/obo/UBERON_0002492	http://purl.obolibrary.org/obo/UPHENO_0084632
+http://purl.obolibrary.org/obo/UBERON_0002491	http://purl.obolibrary.org/obo/UPHENO_0084633
+http://purl.obolibrary.org/obo/UBERON_0005440	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0002490	http://purl.obolibrary.org/obo/UPHENO_0084634
+http://purl.obolibrary.org/obo/UBERON_0002489	http://purl.obolibrary.org/obo/UPHENO_0084635
+http://purl.obolibrary.org/obo/UBERON_0009198	http://purl.obolibrary.org/obo/UPHENO_0084636
+http://purl.obolibrary.org/obo/UBERON_0003954	http://purl.obolibrary.org/obo/UPHENO_0084637
+http://purl.obolibrary.org/obo/UBERON_0009199	http://purl.obolibrary.org/obo/UPHENO_0084638
+http://purl.obolibrary.org/obo/UBERON_0005404	http://purl.obolibrary.org/obo/UPHENO_0084639
+http://purl.obolibrary.org/obo/UBERON_0003685	http://purl.obolibrary.org/obo/UPHENO_0084640
+http://purl.obolibrary.org/obo/UBERON_0002221	http://purl.obolibrary.org/obo/UPHENO_0084641
+http://purl.obolibrary.org/obo/UBERON_0011161	http://purl.obolibrary.org/obo/UPHENO_0084642
+http://purl.obolibrary.org/obo/UBERON_0001725	http://purl.obolibrary.org/obo/UPHENO_0084643
diff --git a/src/curation/upheno-fillers/mp/spatialDeviationOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/mp/spatialDeviationOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..6c5cbd90
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/spatialDeviationOfAnatomicalEntity.tsv
@@ -0,0 +1,3 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001706	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/mp/wrinkledAnatomicalEntity.tsv b/src/curation/upheno-fillers/mp/wrinkledAnatomicalEntity.tsv
new file mode 100644
index 00000000..483374f1
--- /dev/null
+++ b/src/curation/upheno-fillers/mp/wrinkledAnatomicalEntity.tsv
@@ -0,0 +1,5 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0000966	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0000014	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0008852	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/phipo/abnormalAbsenceOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/phipo/abnormalAbsenceOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..cc51e16d
--- /dev/null
+++ b/src/curation/upheno-fillers/phipo/abnormalAbsenceOfAnatomicalEntity.tsv
@@ -0,0 +1,3 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0008523
+http://purl.obolibrary.org/obo/GO_0005634	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/phipo/abnormalAbsenceOfBiologicalProcess.tsv b/src/curation/upheno-fillers/phipo/abnormalAbsenceOfBiologicalProcess.tsv
new file mode 100644
index 00000000..f8a189cd
--- /dev/null
+++ b/src/curation/upheno-fillers/phipo/abnormalAbsenceOfBiologicalProcess.tsv
@@ -0,0 +1,11 @@
+biological_process	defined_class
+http://purl.obolibrary.org/obo/GO_0085030	http://purl.obolibrary.org/obo/UPHENO_0080959
+http://purl.obolibrary.org/obo/GO_0000045	http://purl.obolibrary.org/obo/UPHENO_0080960
+http://purl.obolibrary.org/obo/GO_0044409	http://purl.obolibrary.org/obo/UPHENO_0080961
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UPHENO_0034024
+http://purl.obolibrary.org/obo/GO_0075053	http://purl.obolibrary.org/obo/UPHENO_0080962
+http://purl.obolibrary.org/obo/GO_0008104	http://purl.obolibrary.org/obo/UPHENO_0034055
+http://purl.obolibrary.org/obo/GO_0034504	http://purl.obolibrary.org/obo/UPHENO_0080963
+http://purl.obolibrary.org/obo/GO_0009306	http://purl.obolibrary.org/obo/UPHENO_0080964
+http://purl.obolibrary.org/obo/GO_0106259	http://purl.obolibrary.org/obo/UPHENO_0080965
+http://purl.obolibrary.org/obo/GO_0044114	http://purl.obolibrary.org/obo/UPHENO_0080966
diff --git a/src/curation/upheno-fillers/phipo/abnormalAbsenceOfBiologicalProcessInLocation.tsv b/src/curation/upheno-fillers/phipo/abnormalAbsenceOfBiologicalProcessInLocation.tsv
new file mode 100644
index 00000000..cf2eb4b4
--- /dev/null
+++ b/src/curation/upheno-fillers/phipo/abnormalAbsenceOfBiologicalProcessInLocation.tsv
@@ -0,0 +1,7 @@
+biological_process	location	defined_class
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/GO_0005776	http://purl.obolibrary.org/obo/UPHENO_0083948
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/GO_0005886	http://purl.obolibrary.org/obo/UPHENO_0081904
+http://purl.obolibrary.org/obo/GO_0009085	http://purl.obolibrary.org/obo/CL_0000000	http://purl.obolibrary.org/obo/UPHENO_0081906
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/CL_0000000	http://purl.obolibrary.org/obo/UPHENO_0081907
+http://purl.obolibrary.org/obo/GO_0008104	http://purl.obolibrary.org/obo/GO_0005776	http://purl.obolibrary.org/obo/UPHENO_0083949
+http://purl.obolibrary.org/obo/GO_0008104	http://purl.obolibrary.org/obo/GO_0005886	http://purl.obolibrary.org/obo/UPHENO_0081908
diff --git a/src/curation/upheno-fillers/phipo/abnormalAbsenceOfChemicalEntity.tsv b/src/curation/upheno-fillers/phipo/abnormalAbsenceOfChemicalEntity.tsv
new file mode 100644
index 00000000..17f5c817
--- /dev/null
+++ b/src/curation/upheno-fillers/phipo/abnormalAbsenceOfChemicalEntity.tsv
@@ -0,0 +1,4 @@
+chemical_entity	defined_class
+http://purl.obolibrary.org/obo/CHEBI_33697	http://purl.obolibrary.org/obo/UPHENO_0081911
+http://purl.obolibrary.org/obo/CHEBI_24431	http://purl.obolibrary.org/obo/UPHENO_0048687
+http://purl.obolibrary.org/obo/CHEBI_8653	http://purl.obolibrary.org/obo/UPHENO_0081912
diff --git a/src/curation/upheno-fillers/phipo/abnormalAbsenceOfChemicalEntityInLocation.tsv b/src/curation/upheno-fillers/phipo/abnormalAbsenceOfChemicalEntityInLocation.tsv
new file mode 100644
index 00000000..1f59b6f8
--- /dev/null
+++ b/src/curation/upheno-fillers/phipo/abnormalAbsenceOfChemicalEntityInLocation.tsv
@@ -0,0 +1,3 @@
+chemical_entity	location	defined_class
+http://purl.obolibrary.org/obo/CHEBI_24431	http://purl.obolibrary.org/obo/CL_0000000	http://purl.obolibrary.org/obo/UPHENO_0081772
+http://purl.obolibrary.org/obo/CHEBI_5385	http://purl.obolibrary.org/obo/CL_0000000	http://purl.obolibrary.org/obo/UPHENO_0081773
diff --git a/src/curation/upheno-fillers/phipo/abnormalAbsenceOfMolecularFunction.tsv b/src/curation/upheno-fillers/phipo/abnormalAbsenceOfMolecularFunction.tsv
new file mode 100644
index 00000000..4faa5228
--- /dev/null
+++ b/src/curation/upheno-fillers/phipo/abnormalAbsenceOfMolecularFunction.tsv
@@ -0,0 +1,8 @@
+molecular_function	defined_class
+http://purl.obolibrary.org/obo/GO_0003824	http://purl.obolibrary.org/obo/UPHENO_0081813
+http://purl.obolibrary.org/obo/GO_0030246	http://purl.obolibrary.org/obo/UPHENO_0081814
+http://purl.obolibrary.org/obo/GO_0003674	http://purl.obolibrary.org/obo/UPHENO_0081815
+http://purl.obolibrary.org/obo/GO_0003723	http://purl.obolibrary.org/obo/UPHENO_0081816
+http://purl.obolibrary.org/obo/GO_0008061	http://purl.obolibrary.org/obo/UPHENO_0081817
+http://purl.obolibrary.org/obo/GO_0003677	http://purl.obolibrary.org/obo/UPHENO_0081818
+http://purl.obolibrary.org/obo/GO_0004568	http://purl.obolibrary.org/obo/UPHENO_0081819
diff --git a/src/curation/upheno-fillers/phipo/abnormalAnatomicalEntity.tsv b/src/curation/upheno-fillers/phipo/abnormalAnatomicalEntity.tsv
new file mode 100644
index 00000000..3063613c
--- /dev/null
+++ b/src/curation/upheno-fillers/phipo/abnormalAnatomicalEntity.tsv
@@ -0,0 +1,4 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0002536
+http://purl.obolibrary.org/obo/GO_0005634	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0032179	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/phipo/abnormalBiologicalProcess.tsv b/src/curation/upheno-fillers/phipo/abnormalBiologicalProcess.tsv
new file mode 100644
index 00000000..7f87457e
--- /dev/null
+++ b/src/curation/upheno-fillers/phipo/abnormalBiologicalProcess.tsv
@@ -0,0 +1,33 @@
+biological_process	defined_class
+http://purl.obolibrary.org/obo/GO_0006810	http://purl.obolibrary.org/obo/UPHENO_0049724
+http://purl.obolibrary.org/obo/GO_0006897	http://purl.obolibrary.org/obo/UPHENO_0049592
+http://purl.obolibrary.org/obo/GO_0007127	http://purl.obolibrary.org/obo/UPHENO_0080620
+http://purl.obolibrary.org/obo/GO_0051169	http://purl.obolibrary.org/obo/UPHENO_0049948
+http://purl.obolibrary.org/obo/GO_0034504	http://purl.obolibrary.org/obo/UPHENO_0050434
+http://purl.obolibrary.org/obo/GO_0044237	http://purl.obolibrary.org/obo/UPHENO_0050113
+http://purl.obolibrary.org/obo/GO_0034301	http://purl.obolibrary.org/obo/UPHENO_0080621
+http://purl.obolibrary.org/obo/GO_0140013	http://purl.obolibrary.org/obo/UPHENO_0078724
+http://purl.obolibrary.org/obo/GO_0085030	http://purl.obolibrary.org/obo/UPHENO_0078725
+http://purl.obolibrary.org/obo/GO_0009403	http://purl.obolibrary.org/obo/UPHENO_0078723
+http://purl.obolibrary.org/obo/GO_0022607	http://purl.obolibrary.org/obo/UPHENO_0050001
+http://purl.obolibrary.org/obo/GO_0009987	http://purl.obolibrary.org/obo/UPHENO_0050121
+http://purl.obolibrary.org/obo/GO_0071555	http://purl.obolibrary.org/obo/UPHENO_0078727
+http://purl.obolibrary.org/obo/GO_0009626	http://purl.obolibrary.org/obo/UPHENO_0080622
+http://purl.obolibrary.org/obo/GO_0030436	http://purl.obolibrary.org/obo/UPHENO_0078720
+http://purl.obolibrary.org/obo/GO_0031503	http://purl.obolibrary.org/obo/UPHENO_0049649
+http://purl.obolibrary.org/obo/GO_0006403	http://purl.obolibrary.org/obo/UPHENO_0050218
+http://purl.obolibrary.org/obo/GO_0006468	http://purl.obolibrary.org/obo/UPHENO_0050125
+http://purl.obolibrary.org/obo/GO_0000003	http://purl.obolibrary.org/obo/UPHENO_0051030
+http://purl.obolibrary.org/obo/GO_0051179	http://purl.obolibrary.org/obo/UPHENO_0049927
+http://purl.obolibrary.org/obo/GO_0007034	http://purl.obolibrary.org/obo/UPHENO_0078721
+http://purl.obolibrary.org/obo/GO_1903046	http://purl.obolibrary.org/obo/UPHENO_0049929
+http://purl.obolibrary.org/obo/GO_0008104	http://purl.obolibrary.org/obo/UPHENO_0049934
+http://purl.obolibrary.org/obo/GO_0043476	http://purl.obolibrary.org/obo/UPHENO_0050473
+http://purl.obolibrary.org/obo/GO_0007135	http://purl.obolibrary.org/obo/UPHENO_0080623
+http://purl.obolibrary.org/obo/GO_0019954	http://purl.obolibrary.org/obo/UPHENO_0078722
+http://purl.obolibrary.org/obo/GO_0019953	http://purl.obolibrary.org/obo/UPHENO_0050911
+http://purl.obolibrary.org/obo/GO_0036211	http://purl.obolibrary.org/obo/UPHENO_0049744
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UPHENO_0049587
+http://purl.obolibrary.org/obo/GO_0034293	http://purl.obolibrary.org/obo/UPHENO_0080624
+http://purl.obolibrary.org/obo/GO_0016043	http://purl.obolibrary.org/obo/UPHENO_0050021
+http://purl.obolibrary.org/obo/GO_0015031	http://purl.obolibrary.org/obo/UPHENO_0050102
diff --git a/src/curation/upheno-fillers/phipo/abnormalBiologicalProcessInLocation.tsv b/src/curation/upheno-fillers/phipo/abnormalBiologicalProcessInLocation.tsv
new file mode 100644
index 00000000..df4a5435
--- /dev/null
+++ b/src/curation/upheno-fillers/phipo/abnormalBiologicalProcessInLocation.tsv
@@ -0,0 +1,3 @@
+biological_process	location	defined_class
+http://purl.obolibrary.org/obo/GO_0006033	http://purl.obolibrary.org/obo/CL_0000000	http://purl.obolibrary.org/obo/UPHENO_0081997
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/CL_0000000	http://purl.obolibrary.org/obo/UPHENO_0081999
diff --git a/src/curation/upheno-fillers/phipo/abnormalCellularComponent.tsv b/src/curation/upheno-fillers/phipo/abnormalCellularComponent.tsv
new file mode 100644
index 00000000..d8bb886d
--- /dev/null
+++ b/src/curation/upheno-fillers/phipo/abnormalCellularComponent.tsv
@@ -0,0 +1,4 @@
+cellular_component	defined_class
+http://purl.obolibrary.org/obo/GO_0005575	http://purl.obolibrary.org/obo/UPHENO_0006889
+http://purl.obolibrary.org/obo/GO_0032179	http://purl.obolibrary.org/obo/UPHENO_0082547
+http://purl.obolibrary.org/obo/GO_0005634	http://purl.obolibrary.org/obo/UPHENO_0082548
diff --git a/src/curation/upheno-fillers/phipo/abnormalLevelOfChemicalEntity.tsv b/src/curation/upheno-fillers/phipo/abnormalLevelOfChemicalEntity.tsv
new file mode 100644
index 00000000..89846cda
--- /dev/null
+++ b/src/curation/upheno-fillers/phipo/abnormalLevelOfChemicalEntity.tsv
@@ -0,0 +1,5 @@
+chemical_entity	defined_class
+http://purl.obolibrary.org/obo/CHEBI_36080	http://purl.obolibrary.org/obo/UPHENO_0046362
+http://purl.obolibrary.org/obo/CHEBI_33697	http://purl.obolibrary.org/obo/UPHENO_0081778
+http://purl.obolibrary.org/obo/CHEBI_24431	http://purl.obolibrary.org/obo/UPHENO_0046284
+http://purl.obolibrary.org/obo/CHEBI_17489	http://purl.obolibrary.org/obo/UPHENO_0081779
diff --git a/src/curation/upheno-fillers/phipo/abnormalLevelOfChemicalEntityInLocation.tsv b/src/curation/upheno-fillers/phipo/abnormalLevelOfChemicalEntityInLocation.tsv
new file mode 100644
index 00000000..2979551e
--- /dev/null
+++ b/src/curation/upheno-fillers/phipo/abnormalLevelOfChemicalEntityInLocation.tsv
@@ -0,0 +1,3 @@
+chemical_entity	location	defined_class
+http://purl.obolibrary.org/obo/CHEBI_24431	http://purl.obolibrary.org/obo/CL_0000000	http://purl.obolibrary.org/obo/UPHENO_0082870
+http://purl.obolibrary.org/obo/CHEBI_26523	http://purl.obolibrary.org/obo/CL_0000000	http://purl.obolibrary.org/obo/UPHENO_0082871
diff --git a/src/curation/upheno-fillers/phipo/abnormalMolecularFunction.tsv b/src/curation/upheno-fillers/phipo/abnormalMolecularFunction.tsv
new file mode 100644
index 00000000..b13b6574
--- /dev/null
+++ b/src/curation/upheno-fillers/phipo/abnormalMolecularFunction.tsv
@@ -0,0 +1,9 @@
+molecular_function	defined_class
+http://purl.obolibrary.org/obo/GO_0003824	http://purl.obolibrary.org/obo/UPHENO_0031742
+http://purl.obolibrary.org/obo/GO_0044877	http://purl.obolibrary.org/obo/UPHENO_0080364
+http://purl.obolibrary.org/obo/GO_0030246	http://purl.obolibrary.org/obo/UPHENO_0080365
+http://purl.obolibrary.org/obo/GO_0003674	http://purl.obolibrary.org/obo/UPHENO_0031743
+http://purl.obolibrary.org/obo/GO_0005215	http://purl.obolibrary.org/obo/UPHENO_0080366
+http://purl.obolibrary.org/obo/GO_0003723	http://purl.obolibrary.org/obo/UPHENO_0080367
+http://purl.obolibrary.org/obo/GO_0005515	http://purl.obolibrary.org/obo/UPHENO_0080029
+http://purl.obolibrary.org/obo/GO_0003677	http://purl.obolibrary.org/obo/UPHENO_0080368
diff --git a/src/curation/upheno-fillers/phipo/abnormalMorphologyOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/phipo/abnormalMorphologyOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..57b50c88
--- /dev/null
+++ b/src/curation/upheno-fillers/phipo/abnormalMorphologyOfAnatomicalEntity.tsv
@@ -0,0 +1,258 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
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+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/GO_0005811	http://purl.obolibrary.org/obo/UPHENO_0085933
diff --git a/src/curation/upheno-fillers/phipo/abnormalMorphologyOfCellularComponent.tsv b/src/curation/upheno-fillers/phipo/abnormalMorphologyOfCellularComponent.tsv
new file mode 100644
index 00000000..2f4b1896
--- /dev/null
+++ b/src/curation/upheno-fillers/phipo/abnormalMorphologyOfCellularComponent.tsv
@@ -0,0 +1,3 @@
+cellular_component	defined_class
+http://purl.obolibrary.org/obo/GO_0005575	http://purl.obolibrary.org/obo/UPHENO_0067691
+http://purl.obolibrary.org/obo/GO_0005811	http://purl.obolibrary.org/obo/UPHENO_0082043
diff --git a/src/curation/upheno-fillers/phipo/abnormalMorphologyOfPartOfAnatomicalEntity-modified.tsv b/src/curation/upheno-fillers/phipo/abnormalMorphologyOfPartOfAnatomicalEntity-modified.tsv
new file mode 100644
index 00000000..55ffbc1a
--- /dev/null
+++ b/src/curation/upheno-fillers/phipo/abnormalMorphologyOfPartOfAnatomicalEntity-modified.tsv
@@ -0,0 +1,3 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0005811	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/phipo/abnormalNumberOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/phipo/abnormalNumberOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..dedcc87f
--- /dev/null
+++ b/src/curation/upheno-fillers/phipo/abnormalNumberOfAnatomicalEntity.tsv
@@ -0,0 +1,3 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0011498
+http://purl.obolibrary.org/obo/GO_0005811	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/phipo/abnormalNumberOfCellularComponent.tsv b/src/curation/upheno-fillers/phipo/abnormalNumberOfCellularComponent.tsv
new file mode 100644
index 00000000..f42d6d46
--- /dev/null
+++ b/src/curation/upheno-fillers/phipo/abnormalNumberOfCellularComponent.tsv
@@ -0,0 +1,3 @@
+cellular_component	defined_class
+http://purl.obolibrary.org/obo/GO_0005575	http://purl.obolibrary.org/obo/UPHENO_0046183
+http://purl.obolibrary.org/obo/GO_0005811	http://purl.obolibrary.org/obo/UPHENO_0081812
diff --git a/src/curation/upheno-fillers/phipo/abnormallyDecreasedLengthOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/phipo/abnormallyDecreasedLengthOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..47d678a4
--- /dev/null
+++ b/src/curation/upheno-fillers/phipo/abnormallyDecreasedLengthOfAnatomicalEntity.tsv
@@ -0,0 +1,3 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0046505
+http://purl.obolibrary.org/obo/GO_0032179	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/phipo/abnormallyDecreasedLevelOfChemicalEntity.tsv b/src/curation/upheno-fillers/phipo/abnormallyDecreasedLevelOfChemicalEntity.tsv
new file mode 100644
index 00000000..ce34a11d
--- /dev/null
+++ b/src/curation/upheno-fillers/phipo/abnormallyDecreasedLevelOfChemicalEntity.tsv
@@ -0,0 +1,6 @@
+chemical_entity	defined_class
+http://purl.obolibrary.org/obo/CHEBI_36080	http://purl.obolibrary.org/obo/UPHENO_0081724
+http://purl.obolibrary.org/obo/CHEBI_33697	http://purl.obolibrary.org/obo/UPHENO_0081725
+http://purl.obolibrary.org/obo/CHEBI_24431	http://purl.obolibrary.org/obo/UPHENO_0066739
+http://purl.obolibrary.org/obo/CHEBI_8653	http://purl.obolibrary.org/obo/UPHENO_0081726
+http://purl.obolibrary.org/obo/CHEBI_17489	http://purl.obolibrary.org/obo/UPHENO_0081727
diff --git a/src/curation/upheno-fillers/phipo/abnormallyDecreasedLevelOfChemicalEntityInLocation.tsv b/src/curation/upheno-fillers/phipo/abnormallyDecreasedLevelOfChemicalEntityInLocation.tsv
new file mode 100644
index 00000000..010de07b
--- /dev/null
+++ b/src/curation/upheno-fillers/phipo/abnormallyDecreasedLevelOfChemicalEntityInLocation.tsv
@@ -0,0 +1,3 @@
+chemical_entity	location	defined_class
+http://purl.obolibrary.org/obo/CHEBI_24431	http://purl.obolibrary.org/obo/CL_0000000	http://purl.obolibrary.org/obo/UPHENO_0081898
+http://purl.obolibrary.org/obo/CHEBI_26523	http://purl.obolibrary.org/obo/CL_0000000	http://purl.obolibrary.org/obo/UPHENO_0081899
diff --git a/src/curation/upheno-fillers/phipo/abnormallyDecreasedNumberOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/phipo/abnormallyDecreasedNumberOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..4ccf7aae
--- /dev/null
+++ b/src/curation/upheno-fillers/phipo/abnormallyDecreasedNumberOfAnatomicalEntity.tsv
@@ -0,0 +1,4 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0063722
+http://purl.obolibrary.org/obo/GO_0005811	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0005776	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/phipo/abnormallyDecreasedNumberOfCellularComponent.tsv b/src/curation/upheno-fillers/phipo/abnormallyDecreasedNumberOfCellularComponent.tsv
new file mode 100644
index 00000000..9d937a5f
--- /dev/null
+++ b/src/curation/upheno-fillers/phipo/abnormallyDecreasedNumberOfCellularComponent.tsv
@@ -0,0 +1,4 @@
+cellular_component	defined_class
+http://purl.obolibrary.org/obo/GO_0005575	http://purl.obolibrary.org/obo/UPHENO_0046252
+http://purl.obolibrary.org/obo/GO_0005776	http://purl.obolibrary.org/obo/UPHENO_0082676
+http://purl.obolibrary.org/obo/GO_0005811	http://purl.obolibrary.org/obo/UPHENO_0082677
diff --git a/src/curation/upheno-fillers/phipo/abnormallyDecreasedQualityOfBiologicalProcess.tsv b/src/curation/upheno-fillers/phipo/abnormallyDecreasedQualityOfBiologicalProcess.tsv
new file mode 100644
index 00000000..57cf7fa9
--- /dev/null
+++ b/src/curation/upheno-fillers/phipo/abnormallyDecreasedQualityOfBiologicalProcess.tsv
@@ -0,0 +1,7 @@
+biological_process	defined_class
+http://purl.obolibrary.org/obo/GO_1903409	http://purl.obolibrary.org/obo/UPHENO_0082009
+http://purl.obolibrary.org/obo/GO_0006468	http://purl.obolibrary.org/obo/UPHENO_0052798
+http://purl.obolibrary.org/obo/GO_0008283	http://purl.obolibrary.org/obo/UPHENO_0052500
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UPHENO_0052178
+http://purl.obolibrary.org/obo/GO_0043482	http://purl.obolibrary.org/obo/UPHENO_0079497
+http://purl.obolibrary.org/obo/GO_0016042	http://purl.obolibrary.org/obo/UPHENO_0082010
diff --git a/src/curation/upheno-fillers/phipo/abnormallyDecreasedRateOfBiologicalProcess.tsv b/src/curation/upheno-fillers/phipo/abnormallyDecreasedRateOfBiologicalProcess.tsv
new file mode 100644
index 00000000..b7254537
--- /dev/null
+++ b/src/curation/upheno-fillers/phipo/abnormallyDecreasedRateOfBiologicalProcess.tsv
@@ -0,0 +1,6 @@
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diff --git a/src/curation/upheno-fillers/phipo/abnormallyDecreasedRateOfMolecularFunction.tsv b/src/curation/upheno-fillers/phipo/abnormallyDecreasedRateOfMolecularFunction.tsv
new file mode 100644
index 00000000..aa9220ae
--- /dev/null
+++ b/src/curation/upheno-fillers/phipo/abnormallyDecreasedRateOfMolecularFunction.tsv
@@ -0,0 +1,3 @@
+molecular_function	defined_class
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diff --git a/src/curation/upheno-fillers/phipo/abnormallyDecreasedResistanceOfWholeOrganismToChemicalEntity.tsv b/src/curation/upheno-fillers/phipo/abnormallyDecreasedResistanceOfWholeOrganismToChemicalEntity.tsv
new file mode 100644
index 00000000..272e7d92
--- /dev/null
+++ b/src/curation/upheno-fillers/phipo/abnormallyDecreasedResistanceOfWholeOrganismToChemicalEntity.tsv
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diff --git a/src/curation/upheno-fillers/phipo/abnormallyDecreasedResistanceOfWholeOrganismToEntity.tsv b/src/curation/upheno-fillers/phipo/abnormallyDecreasedResistanceOfWholeOrganismToEntity.tsv
new file mode 100644
index 00000000..a2c67f53
--- /dev/null
+++ b/src/curation/upheno-fillers/phipo/abnormallyDecreasedResistanceOfWholeOrganismToEntity.tsv
@@ -0,0 +1,199 @@
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+http://purl.obolibrary.org/obo/CHEBI_87185	http://purl.obolibrary.org/obo/UPHENO_0076283
+http://purl.obolibrary.org/obo/CHEBI_81758	http://purl.obolibrary.org/obo/UPHENO_0076284
diff --git a/src/curation/upheno-fillers/phipo/abnormallyDecreasedSizeOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/phipo/abnormallyDecreasedSizeOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..3cdbec4f
--- /dev/null
+++ b/src/curation/upheno-fillers/phipo/abnormallyDecreasedSizeOfAnatomicalEntity.tsv
@@ -0,0 +1,3 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0068971
+http://purl.obolibrary.org/obo/GO_0005811	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/phipo/abnormallyDecreasedSizeOfCellularComponent.tsv b/src/curation/upheno-fillers/phipo/abnormallyDecreasedSizeOfCellularComponent.tsv
new file mode 100644
index 00000000..b04e3d35
--- /dev/null
+++ b/src/curation/upheno-fillers/phipo/abnormallyDecreasedSizeOfCellularComponent.tsv
@@ -0,0 +1,3 @@
+entity	defined_class
+http://purl.obolibrary.org/obo/GO_0005575	http://purl.obolibrary.org/obo/UPHENO_0082013
+http://purl.obolibrary.org/obo/GO_0005811	http://purl.obolibrary.org/obo/UPHENO_0082015
diff --git a/src/curation/upheno-fillers/phipo/abnormallyDelayedBiologicalProcess.tsv b/src/curation/upheno-fillers/phipo/abnormallyDelayedBiologicalProcess.tsv
new file mode 100644
index 00000000..0f65b325
--- /dev/null
+++ b/src/curation/upheno-fillers/phipo/abnormallyDelayedBiologicalProcess.tsv
@@ -0,0 +1,8 @@
+biological_process	defined_class
+http://purl.obolibrary.org/obo/GO_0030436	http://purl.obolibrary.org/obo/UPHENO_0080544
+http://purl.obolibrary.org/obo/GO_0044409	http://purl.obolibrary.org/obo/UPHENO_0080545
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UPHENO_0000543
+http://purl.obolibrary.org/obo/GO_0034293	http://purl.obolibrary.org/obo/UPHENO_0080546
+http://purl.obolibrary.org/obo/GO_0075053	http://purl.obolibrary.org/obo/UPHENO_0080547
+http://purl.obolibrary.org/obo/GO_0106259	http://purl.obolibrary.org/obo/UPHENO_0080548
+http://purl.obolibrary.org/obo/GO_0044114	http://purl.obolibrary.org/obo/UPHENO_0080549
diff --git a/src/curation/upheno-fillers/phipo/abnormallyIncreasedLengthOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/phipo/abnormallyIncreasedLengthOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..96ffc05b
--- /dev/null
+++ b/src/curation/upheno-fillers/phipo/abnormallyIncreasedLengthOfAnatomicalEntity.tsv
@@ -0,0 +1,3 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0072195
+http://purl.obolibrary.org/obo/GO_0032179	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/phipo/abnormallyIncreasedLevelOfChemicalEntity.tsv b/src/curation/upheno-fillers/phipo/abnormallyIncreasedLevelOfChemicalEntity.tsv
new file mode 100644
index 00000000..d3ced185
--- /dev/null
+++ b/src/curation/upheno-fillers/phipo/abnormallyIncreasedLevelOfChemicalEntity.tsv
@@ -0,0 +1,6 @@
+chemical_entity	defined_class
+http://purl.obolibrary.org/obo/CHEBI_36080	http://purl.obolibrary.org/obo/UPHENO_0082943
+http://purl.obolibrary.org/obo/CHEBI_33697	http://purl.obolibrary.org/obo/UPHENO_0082944
+http://purl.obolibrary.org/obo/CHEBI_24431	http://purl.obolibrary.org/obo/UPHENO_0048707
+http://purl.obolibrary.org/obo/CHEBI_8653	http://purl.obolibrary.org/obo/UPHENO_0082945
+http://purl.obolibrary.org/obo/CHEBI_17489	http://purl.obolibrary.org/obo/UPHENO_0082946
diff --git a/src/curation/upheno-fillers/phipo/abnormallyIncreasedNumberOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/phipo/abnormallyIncreasedNumberOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..68643064
--- /dev/null
+++ b/src/curation/upheno-fillers/phipo/abnormallyIncreasedNumberOfAnatomicalEntity.tsv
@@ -0,0 +1,4 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/GO_0030428	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0014240
+http://purl.obolibrary.org/obo/GO_0005811	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/phipo/abnormallyIncreasedNumberOfCellularComponent.tsv b/src/curation/upheno-fillers/phipo/abnormallyIncreasedNumberOfCellularComponent.tsv
new file mode 100644
index 00000000..b32bc2bd
--- /dev/null
+++ b/src/curation/upheno-fillers/phipo/abnormallyIncreasedNumberOfCellularComponent.tsv
@@ -0,0 +1,4 @@
+cellular_component	defined_class
+http://purl.obolibrary.org/obo/GO_0005575	http://purl.obolibrary.org/obo/UPHENO_0063672
+http://purl.obolibrary.org/obo/GO_0030428	http://purl.obolibrary.org/obo/UPHENO_0080533
+http://purl.obolibrary.org/obo/GO_0005811	http://purl.obolibrary.org/obo/UPHENO_0080534
diff --git a/src/curation/upheno-fillers/phipo/abnormallyIncreasedQualityOfBiologicalProcess.tsv b/src/curation/upheno-fillers/phipo/abnormallyIncreasedQualityOfBiologicalProcess.tsv
new file mode 100644
index 00000000..e5434d38
--- /dev/null
+++ b/src/curation/upheno-fillers/phipo/abnormallyIncreasedQualityOfBiologicalProcess.tsv
@@ -0,0 +1,4 @@
+biological_process	defined_class
+http://purl.obolibrary.org/obo/GO_0008283	http://purl.obolibrary.org/obo/UPHENO_0080677
+http://purl.obolibrary.org/obo/GO_0044409	http://purl.obolibrary.org/obo/UPHENO_0080763
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UPHENO_0080662
diff --git a/src/curation/upheno-fillers/phipo/abnormallyIncreasedRateOfBiologicalProcess.tsv b/src/curation/upheno-fillers/phipo/abnormallyIncreasedRateOfBiologicalProcess.tsv
new file mode 100644
index 00000000..ee604f30
--- /dev/null
+++ b/src/curation/upheno-fillers/phipo/abnormallyIncreasedRateOfBiologicalProcess.tsv
@@ -0,0 +1,6 @@
+biological_process	defined_class
+http://purl.obolibrary.org/obo/GO_0008283	http://purl.obolibrary.org/obo/UPHENO_0055106
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UPHENO_0054970
+http://purl.obolibrary.org/obo/GO_0043482	http://purl.obolibrary.org/obo/UPHENO_0076689
+http://purl.obolibrary.org/obo/GO_0009847	http://purl.obolibrary.org/obo/UPHENO_0076691
+http://purl.obolibrary.org/obo/GO_0044114	http://purl.obolibrary.org/obo/UPHENO_0082833
diff --git a/src/curation/upheno-fillers/phipo/abnormallyIncreasedRateOfMolecularFunction.tsv b/src/curation/upheno-fillers/phipo/abnormallyIncreasedRateOfMolecularFunction.tsv
new file mode 100644
index 00000000..be028414
--- /dev/null
+++ b/src/curation/upheno-fillers/phipo/abnormallyIncreasedRateOfMolecularFunction.tsv
@@ -0,0 +1,5 @@
+molecular_function	defined_class
+http://purl.obolibrary.org/obo/GO_0003824	http://purl.obolibrary.org/obo/UPHENO_0048683
+http://purl.obolibrary.org/obo/GO_0003674	http://purl.obolibrary.org/obo/UPHENO_0048661
+http://purl.obolibrary.org/obo/GO_0003723	http://purl.obolibrary.org/obo/UPHENO_0080855
+http://purl.obolibrary.org/obo/GO_0004568	http://purl.obolibrary.org/obo/UPHENO_0080856
diff --git a/src/curation/upheno-fillers/phipo/abnormallyIncreasedResistanceOfWholeOrganismToChemicalEntity.tsv b/src/curation/upheno-fillers/phipo/abnormallyIncreasedResistanceOfWholeOrganismToChemicalEntity.tsv
new file mode 100644
index 00000000..104010b4
--- /dev/null
+++ b/src/curation/upheno-fillers/phipo/abnormallyIncreasedResistanceOfWholeOrganismToChemicalEntity.tsv
@@ -0,0 +1,191 @@
+chemical_entity	defined_class
+http://purl.obolibrary.org/obo/CHEBI_45081	http://purl.obolibrary.org/obo/UPHENO_0077009
+http://purl.obolibrary.org/obo/CHEBI_27656	http://purl.obolibrary.org/obo/UPHENO_0077010
+http://purl.obolibrary.org/obo/CHEBI_28864	http://purl.obolibrary.org/obo/UPHENO_0077011
+http://purl.obolibrary.org/obo/CHEBI_27412	http://purl.obolibrary.org/obo/UPHENO_0077012
+http://purl.obolibrary.org/obo/CHEBI_69136	http://purl.obolibrary.org/obo/UPHENO_0077013
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+http://purl.obolibrary.org/obo/CHEBI_7809	http://purl.obolibrary.org/obo/UPHENO_0077016
+http://purl.obolibrary.org/obo/CHEBI_7528	http://purl.obolibrary.org/obo/UPHENO_0077017
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+http://purl.obolibrary.org/obo/CHEBI_48080	http://purl.obolibrary.org/obo/UPHENO_0077019
+http://purl.obolibrary.org/obo/CHEBI_204928	http://purl.obolibrary.org/obo/UPHENO_0077020
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diff --git a/src/curation/upheno-fillers/phipo/abnormallyIncreasedResistanceOfWholeOrganismToEntity.tsv b/src/curation/upheno-fillers/phipo/abnormallyIncreasedResistanceOfWholeOrganismToEntity.tsv
new file mode 100644
index 00000000..801988ed
--- /dev/null
+++ b/src/curation/upheno-fillers/phipo/abnormallyIncreasedResistanceOfWholeOrganismToEntity.tsv
@@ -0,0 +1,192 @@
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+http://purl.obolibrary.org/obo/CHEBI_17698	http://purl.obolibrary.org/obo/UPHENO_0078936
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+http://purl.obolibrary.org/obo/CHEBI_149836	http://purl.obolibrary.org/obo/UPHENO_0078949
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+http://purl.obolibrary.org/obo/CHEBI_3749	http://purl.obolibrary.org/obo/UPHENO_0078970
+http://purl.obolibrary.org/obo/CHEBI_87185	http://purl.obolibrary.org/obo/UPHENO_0078971
+http://purl.obolibrary.org/obo/CHEBI_81758	http://purl.obolibrary.org/obo/UPHENO_0078972
+http://purl.obolibrary.org/obo/CHEBI_46633	http://purl.obolibrary.org/obo/UPHENO_0078973
+http://purl.obolibrary.org/obo/CHEBI_81913	http://purl.obolibrary.org/obo/UPHENO_0078974
+http://purl.obolibrary.org/obo/CHEBI_81917	http://purl.obolibrary.org/obo/UPHENO_0078975
diff --git a/src/curation/upheno-fillers/phipo/abnormallyIncreasedSizeOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/phipo/abnormallyIncreasedSizeOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..eb72f8ef
--- /dev/null
+++ b/src/curation/upheno-fillers/phipo/abnormallyIncreasedSizeOfAnatomicalEntity.tsv
@@ -0,0 +1,3 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0001072
+http://purl.obolibrary.org/obo/GO_0005811	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/phipo/abnormallyIncreasedSizeOfCellularComponent.tsv b/src/curation/upheno-fillers/phipo/abnormallyIncreasedSizeOfCellularComponent.tsv
new file mode 100644
index 00000000..1f7ea178
--- /dev/null
+++ b/src/curation/upheno-fillers/phipo/abnormallyIncreasedSizeOfCellularComponent.tsv
@@ -0,0 +1,3 @@
+entity	defined_class
+http://purl.obolibrary.org/obo/GO_0005575	http://purl.obolibrary.org/obo/UPHENO_0080309
+http://purl.obolibrary.org/obo/GO_0005811	http://purl.obolibrary.org/obo/UPHENO_0080312
diff --git a/src/curation/upheno-fillers/phipo/abnormallyPrematureBiologicalProcess.tsv b/src/curation/upheno-fillers/phipo/abnormallyPrematureBiologicalProcess.tsv
new file mode 100644
index 00000000..91068811
--- /dev/null
+++ b/src/curation/upheno-fillers/phipo/abnormallyPrematureBiologicalProcess.tsv
@@ -0,0 +1,6 @@
+biological_process	defined_class
+http://purl.obolibrary.org/obo/GO_0030436	http://purl.obolibrary.org/obo/UPHENO_0080422
+http://purl.obolibrary.org/obo/GO_0044409	http://purl.obolibrary.org/obo/UPHENO_0080423
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UPHENO_0049440
+http://purl.obolibrary.org/obo/GO_0034293	http://purl.obolibrary.org/obo/UPHENO_0080424
+http://purl.obolibrary.org/obo/GO_0106259	http://purl.obolibrary.org/obo/UPHENO_0080425
diff --git a/src/curation/upheno-fillers/planp/abnormalAbsenceOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/planp/abnormalAbsenceOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..8185662f
--- /dev/null
+++ b/src/curation/upheno-fillers/planp/abnormalAbsenceOfAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0008523
diff --git a/src/curation/upheno-fillers/planp/abnormalAbsenceOfAnatomicalEntityDueToDegeneration.tsv b/src/curation/upheno-fillers/planp/abnormalAbsenceOfAnatomicalEntityDueToDegeneration.tsv
new file mode 100644
index 00000000..9b835cb6
--- /dev/null
+++ b/src/curation/upheno-fillers/planp/abnormalAbsenceOfAnatomicalEntityDueToDegeneration.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0046054
diff --git a/src/curation/upheno-fillers/planp/abnormalAbsenceOfPigmentationOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/planp/abnormalAbsenceOfPigmentationOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..f9722607
--- /dev/null
+++ b/src/curation/upheno-fillers/planp/abnormalAbsenceOfPigmentationOfAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0008222
diff --git a/src/curation/upheno-fillers/planp/abnormalAnatomicalEntity.tsv b/src/curation/upheno-fillers/planp/abnormalAnatomicalEntity.tsv
new file mode 100644
index 00000000..ebe14380
--- /dev/null
+++ b/src/curation/upheno-fillers/planp/abnormalAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0002536
diff --git a/src/curation/upheno-fillers/planp/abnormalCellularComponent.tsv b/src/curation/upheno-fillers/planp/abnormalCellularComponent.tsv
new file mode 100644
index 00000000..ef36ea60
--- /dev/null
+++ b/src/curation/upheno-fillers/planp/abnormalCellularComponent.tsv
@@ -0,0 +1,2 @@
+cellular_component	defined_class
+http://purl.obolibrary.org/obo/GO_0005575	http://purl.obolibrary.org/obo/UPHENO_0006889
diff --git a/src/curation/upheno-fillers/planp/abnormalDistanceBetweenAnatomicalEntities.tsv b/src/curation/upheno-fillers/planp/abnormalDistanceBetweenAnatomicalEntities.tsv
new file mode 100644
index 00000000..23368408
--- /dev/null
+++ b/src/curation/upheno-fillers/planp/abnormalDistanceBetweenAnatomicalEntities.tsv
@@ -0,0 +1,2 @@
+anatomical_entity1	anatomical_entity2	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0012019
diff --git a/src/curation/upheno-fillers/planp/abnormalMobilityOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/planp/abnormalMobilityOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..c6805b06
--- /dev/null
+++ b/src/curation/upheno-fillers/planp/abnormalMobilityOfAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0076943
diff --git a/src/curation/upheno-fillers/planp/abnormalMorphologyOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/planp/abnormalMorphologyOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..00ede9ee
--- /dev/null
+++ b/src/curation/upheno-fillers/planp/abnormalMorphologyOfAnatomicalEntity.tsv
@@ -0,0 +1,17 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
diff --git a/src/curation/upheno-fillers/planp/abnormalMorphologyOfPartOfAnatomicalEntity-modified.tsv b/src/curation/upheno-fillers/planp/abnormalMorphologyOfPartOfAnatomicalEntity-modified.tsv
new file mode 100644
index 00000000..57c76cbb
--- /dev/null
+++ b/src/curation/upheno-fillers/planp/abnormalMorphologyOfPartOfAnatomicalEntity-modified.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/planp/abnormalNumberOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/planp/abnormalNumberOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..cd61b297
--- /dev/null
+++ b/src/curation/upheno-fillers/planp/abnormalNumberOfAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0011498
diff --git a/src/curation/upheno-fillers/planp/abnormalPigmentationOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/planp/abnormalPigmentationOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..9043ea08
--- /dev/null
+++ b/src/curation/upheno-fillers/planp/abnormalPigmentationOfAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0066794
diff --git a/src/curation/upheno-fillers/planp/abnormalShapeOfAnatomicalEntityByShapeType.tsv b/src/curation/upheno-fillers/planp/abnormalShapeOfAnatomicalEntityByShapeType.tsv
new file mode 100644
index 00000000..f9964f25
--- /dev/null
+++ b/src/curation/upheno-fillers/planp/abnormalShapeOfAnatomicalEntityByShapeType.tsv
@@ -0,0 +1,7 @@
+entity	shape	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0002239	http://purl.obolibrary.org/obo/UPHENO_0042009
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0041226
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0002063	http://purl.obolibrary.org/obo/UPHENO_0041789
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0002164	http://purl.obolibrary.org/obo/UPHENO_0042473
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0001799	http://purl.obolibrary.org/obo/UPHENO_0041174
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0002258	http://purl.obolibrary.org/obo/UPHENO_0041793
diff --git a/src/curation/upheno-fillers/planp/abnormalShapeOfPhysicalEntity.tsv b/src/curation/upheno-fillers/planp/abnormalShapeOfPhysicalEntity.tsv
new file mode 100644
index 00000000..32373cd2
--- /dev/null
+++ b/src/curation/upheno-fillers/planp/abnormalShapeOfPhysicalEntity.tsv
@@ -0,0 +1,2 @@
+entity	defined_class
+http://purl.obolibrary.org/obo/BFO_0000002	http://purl.obolibrary.org/obo/UPHENO_0080300
diff --git a/src/curation/upheno-fillers/planp/abnormalSizeOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/planp/abnormalSizeOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..c4170116
--- /dev/null
+++ b/src/curation/upheno-fillers/planp/abnormalSizeOfAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0075195
diff --git a/src/curation/upheno-fillers/planp/abnormallyCurvedAnatomicalEntityByOrientation.tsv b/src/curation/upheno-fillers/planp/abnormallyCurvedAnatomicalEntityByOrientation.tsv
new file mode 100644
index 00000000..7b097589
--- /dev/null
+++ b/src/curation/upheno-fillers/planp/abnormallyCurvedAnatomicalEntityByOrientation.tsv
@@ -0,0 +1,3 @@
+anatomical_entity	orientation	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0000406	http://purl.obolibrary.org/obo/UPHENO_0031193
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0002164	http://purl.obolibrary.org/obo/UPHENO_0031740
diff --git a/src/curation/upheno-fillers/planp/abnormallyDecreasedDistanceBetweenAnatomicalEntities.tsv b/src/curation/upheno-fillers/planp/abnormallyDecreasedDistanceBetweenAnatomicalEntities.tsv
new file mode 100644
index 00000000..e35085c1
--- /dev/null
+++ b/src/curation/upheno-fillers/planp/abnormallyDecreasedDistanceBetweenAnatomicalEntities.tsv
@@ -0,0 +1,2 @@
+anatomical_entity1	anatomical_entity2	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0010600
diff --git a/src/curation/upheno-fillers/planp/abnormallyDecreasedLengthOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/planp/abnormallyDecreasedLengthOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..c661e30a
--- /dev/null
+++ b/src/curation/upheno-fillers/planp/abnormallyDecreasedLengthOfAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0046505
diff --git a/src/curation/upheno-fillers/planp/abnormallyDecreasedMobilityOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/planp/abnormallyDecreasedMobilityOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..ca81007f
--- /dev/null
+++ b/src/curation/upheno-fillers/planp/abnormallyDecreasedMobilityOfAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0076671
diff --git a/src/curation/upheno-fillers/planp/abnormallyDecreasedNumberOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/planp/abnormallyDecreasedNumberOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..c057f89c
--- /dev/null
+++ b/src/curation/upheno-fillers/planp/abnormallyDecreasedNumberOfAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0063722
diff --git a/src/curation/upheno-fillers/planp/abnormallyDecreasedPigmentationOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/planp/abnormallyDecreasedPigmentationOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..546f08b6
--- /dev/null
+++ b/src/curation/upheno-fillers/planp/abnormallyDecreasedPigmentationOfAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0018526
diff --git a/src/curation/upheno-fillers/planp/abnormallyDecreasedSpeedOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/planp/abnormallyDecreasedSpeedOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..b22947ce
--- /dev/null
+++ b/src/curation/upheno-fillers/planp/abnormallyDecreasedSpeedOfAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0081910
diff --git a/src/curation/upheno-fillers/planp/abnormallyDecreasedWidthOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/planp/abnormallyDecreasedWidthOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..f99bd232
--- /dev/null
+++ b/src/curation/upheno-fillers/planp/abnormallyDecreasedWidthOfAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0054567
diff --git a/src/curation/upheno-fillers/planp/abnormallyImmobileAnatomicalEntity.tsv b/src/curation/upheno-fillers/planp/abnormallyImmobileAnatomicalEntity.tsv
new file mode 100644
index 00000000..b7e27978
--- /dev/null
+++ b/src/curation/upheno-fillers/planp/abnormallyImmobileAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0081417
diff --git a/src/curation/upheno-fillers/planp/abnormallyIncreasedDistanceBetweenAnatomicalEntities.tsv b/src/curation/upheno-fillers/planp/abnormallyIncreasedDistanceBetweenAnatomicalEntities.tsv
new file mode 100644
index 00000000..c3bfcd11
--- /dev/null
+++ b/src/curation/upheno-fillers/planp/abnormallyIncreasedDistanceBetweenAnatomicalEntities.tsv
@@ -0,0 +1,2 @@
+entity1	entity2	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0054477
diff --git a/src/curation/upheno-fillers/planp/abnormallyIncreasedLengthOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/planp/abnormallyIncreasedLengthOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..b9cad5a7
--- /dev/null
+++ b/src/curation/upheno-fillers/planp/abnormallyIncreasedLengthOfAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0072195
diff --git a/src/curation/upheno-fillers/planp/abnormallyIncreasedNumberOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/planp/abnormallyIncreasedNumberOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..c6cfd6eb
--- /dev/null
+++ b/src/curation/upheno-fillers/planp/abnormallyIncreasedNumberOfAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0014240
diff --git a/src/curation/upheno-fillers/planp/abnormallyIncreasedPigmentationOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/planp/abnormallyIncreasedPigmentationOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..3715f319
--- /dev/null
+++ b/src/curation/upheno-fillers/planp/abnormallyIncreasedPigmentationOfAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0010666
diff --git a/src/curation/upheno-fillers/planp/abnormallyIncreasedSpeedOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/planp/abnormallyIncreasedSpeedOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..91920129
--- /dev/null
+++ b/src/curation/upheno-fillers/planp/abnormallyIncreasedSpeedOfAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0080426
diff --git a/src/curation/upheno-fillers/planp/abnormallyIncreasedWidthOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/planp/abnormallyIncreasedWidthOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..a0f1a8f6
--- /dev/null
+++ b/src/curation/upheno-fillers/planp/abnormallyIncreasedWidthOfAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0006161
diff --git a/src/curation/upheno-fillers/planp/edematousAnatomicalEntity.tsv b/src/curation/upheno-fillers/planp/edematousAnatomicalEntity.tsv
new file mode 100644
index 00000000..b9751032
--- /dev/null
+++ b/src/curation/upheno-fillers/planp/edematousAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0082498
diff --git a/src/curation/upheno-fillers/planp/hypoplasticAnatomicalEntity.tsv b/src/curation/upheno-fillers/planp/hypoplasticAnatomicalEntity.tsv
new file mode 100644
index 00000000..e31fa94a
--- /dev/null
+++ b/src/curation/upheno-fillers/planp/hypoplasticAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0081091
diff --git a/src/curation/upheno-fillers/planp/lesionedAnatomicalEntity.tsv b/src/curation/upheno-fillers/planp/lesionedAnatomicalEntity.tsv
new file mode 100644
index 00000000..b8d459b6
--- /dev/null
+++ b/src/curation/upheno-fillers/planp/lesionedAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0082742
diff --git a/src/curation/upheno-fillers/wbphenotype/abnormalAbsenceOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/wbphenotype/abnormalAbsenceOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..a9f4d532
--- /dev/null
+++ b/src/curation/upheno-fillers/wbphenotype/abnormalAbsenceOfAnatomicalEntity.tsv
@@ -0,0 +1,5 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0008523
+http://purl.obolibrary.org/obo/CL_0000300	http://purl.obolibrary.org/obo/UPHENO_0078452
+http://purl.obolibrary.org/obo/GO_0005929	http://purl.obolibrary.org/obo/UPHENO_0078453
+http://purl.obolibrary.org/obo/GO_0005819	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/wbphenotype/abnormalAbsenceOfBiologicalProcess.tsv b/src/curation/upheno-fillers/wbphenotype/abnormalAbsenceOfBiologicalProcess.tsv
new file mode 100644
index 00000000..1984debe
--- /dev/null
+++ b/src/curation/upheno-fillers/wbphenotype/abnormalAbsenceOfBiologicalProcess.tsv
@@ -0,0 +1,14 @@
+biological_process	defined_class
+http://purl.obolibrary.org/obo/GO_0043050	http://purl.obolibrary.org/obo/UPHENO_0034085
+http://purl.obolibrary.org/obo/GO_0051301	http://purl.obolibrary.org/obo/UPHENO_0034038
+http://purl.obolibrary.org/obo/GO_0042073	http://purl.obolibrary.org/obo/UPHENO_0034040
+http://purl.obolibrary.org/obo/GO_0043054	http://purl.obolibrary.org/obo/UPHENO_0034087
+http://purl.obolibrary.org/obo/GO_0043057	http://purl.obolibrary.org/obo/UPHENO_0034089
+http://purl.obolibrary.org/obo/GO_0016477	http://purl.obolibrary.org/obo/UPHENO_0034078
+http://purl.obolibrary.org/obo/GO_0035882	http://purl.obolibrary.org/obo/UPHENO_0034061
+http://purl.obolibrary.org/obo/GO_0035188	http://purl.obolibrary.org/obo/UPHENO_0034094
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UPHENO_0034024
+http://purl.obolibrary.org/obo/GO_0030261	http://purl.obolibrary.org/obo/UPHENO_0034045
+http://purl.obolibrary.org/obo/GO_0022618	http://purl.obolibrary.org/obo/UPHENO_0034068
+http://purl.obolibrary.org/obo/GO_0006915	http://purl.obolibrary.org/obo/UPHENO_0034080
+http://purl.obolibrary.org/obo/GO_0030590	http://purl.obolibrary.org/obo/UPHENO_0034070
diff --git a/src/curation/upheno-fillers/wbphenotype/abnormalAnatomicalEntity-modified.tsv b/src/curation/upheno-fillers/wbphenotype/abnormalAnatomicalEntity-modified.tsv
new file mode 100644
index 00000000..57c76cbb
--- /dev/null
+++ b/src/curation/upheno-fillers/wbphenotype/abnormalAnatomicalEntity-modified.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/wbphenotype/abnormalAnatomicalEntity.tsv b/src/curation/upheno-fillers/wbphenotype/abnormalAnatomicalEntity.tsv
new file mode 100644
index 00000000..5771a1f9
--- /dev/null
+++ b/src/curation/upheno-fillers/wbphenotype/abnormalAnatomicalEntity.tsv
@@ -0,0 +1,3 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/GO_0005912	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0002536
diff --git a/src/curation/upheno-fillers/wbphenotype/abnormalAnatomicalEntityNotParts.tsv b/src/curation/upheno-fillers/wbphenotype/abnormalAnatomicalEntityNotParts.tsv
new file mode 100644
index 00000000..59e48c63
--- /dev/null
+++ b/src/curation/upheno-fillers/wbphenotype/abnormalAnatomicalEntityNotParts.tsv
@@ -0,0 +1,5 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0075696
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0075696
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0075696
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0075696
diff --git a/src/curation/upheno-fillers/wbphenotype/abnormalBiologicalProcess.tsv b/src/curation/upheno-fillers/wbphenotype/abnormalBiologicalProcess.tsv
new file mode 100644
index 00000000..a552a017
--- /dev/null
+++ b/src/curation/upheno-fillers/wbphenotype/abnormalBiologicalProcess.tsv
@@ -0,0 +1,205 @@
+biological_process	defined_class
+http://purl.obolibrary.org/obo/GO_0006897	http://purl.obolibrary.org/obo/UPHENO_0049592
+http://purl.obolibrary.org/obo/GO_0007622	http://purl.obolibrary.org/obo/UPHENO_0049591
+http://purl.obolibrary.org/obo/GO_0006412	http://purl.obolibrary.org/obo/UPHENO_0049594
+http://purl.obolibrary.org/obo/GO_0001764	http://purl.obolibrary.org/obo/UPHENO_0049852
+http://purl.obolibrary.org/obo/GO_0007620	http://purl.obolibrary.org/obo/UPHENO_0049597
+http://purl.obolibrary.org/obo/GO_0008283	http://purl.obolibrary.org/obo/UPHENO_0049858
+http://purl.obolibrary.org/obo/GO_0018991	http://purl.obolibrary.org/obo/UPHENO_0049603
+http://purl.obolibrary.org/obo/GO_0007613	http://purl.obolibrary.org/obo/UPHENO_0050579
+http://purl.obolibrary.org/obo/GO_0000423	http://purl.obolibrary.org/obo/UPHENO_0078650
+http://purl.obolibrary.org/obo/GO_0006887	http://purl.obolibrary.org/obo/UPHENO_0049604
+http://purl.obolibrary.org/obo/GO_0051932	http://purl.obolibrary.org/obo/UPHENO_0049606
+http://purl.obolibrary.org/obo/GO_0006401	http://purl.obolibrary.org/obo/UPHENO_0049611
+http://purl.obolibrary.org/obo/GO_0006406	http://purl.obolibrary.org/obo/UPHENO_0049616
+http://purl.obolibrary.org/obo/GO_0098542	http://purl.obolibrary.org/obo/UPHENO_0049863
+http://purl.obolibrary.org/obo/GO_0045132	http://purl.obolibrary.org/obo/UPHENO_0049621
+http://purl.obolibrary.org/obo/GO_0007296	http://purl.obolibrary.org/obo/UPHENO_0049865
+http://purl.obolibrary.org/obo/GO_0007059	http://purl.obolibrary.org/obo/UPHENO_0049866
+http://purl.obolibrary.org/obo/GO_0007610	http://purl.obolibrary.org/obo/UPHENO_0049622
+http://purl.obolibrary.org/obo/GO_0002164	http://purl.obolibrary.org/obo/UPHENO_0049624
+http://purl.obolibrary.org/obo/GO_0040004	http://purl.obolibrary.org/obo/UPHENO_0049869
+http://purl.obolibrary.org/obo/GO_0010467	http://purl.obolibrary.org/obo/UPHENO_0049870
+http://purl.obolibrary.org/obo/GO_0016203	http://purl.obolibrary.org/obo/UPHENO_0049625
+http://purl.obolibrary.org/obo/GO_0035882	http://purl.obolibrary.org/obo/UPHENO_0049872
+http://purl.obolibrary.org/obo/GO_0040007	http://purl.obolibrary.org/obo/UPHENO_0049874
+http://purl.obolibrary.org/obo/GO_0042428	http://purl.obolibrary.org/obo/UPHENO_0049876
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UPHENO_0049587
+http://purl.obolibrary.org/obo/GO_0099636	http://purl.obolibrary.org/obo/UPHENO_0080603
+http://purl.obolibrary.org/obo/GO_0001666	http://purl.obolibrary.org/obo/UPHENO_0049879
+http://purl.obolibrary.org/obo/GO_0046333	http://purl.obolibrary.org/obo/UPHENO_0049632
+http://purl.obolibrary.org/obo/GO_0048512	http://purl.obolibrary.org/obo/UPHENO_0049633
+http://purl.obolibrary.org/obo/GO_0043068	http://purl.obolibrary.org/obo/UPHENO_0049636
+http://purl.obolibrary.org/obo/GO_0006310	http://purl.obolibrary.org/obo/UPHENO_0049639
+http://purl.obolibrary.org/obo/GO_0009269	http://purl.obolibrary.org/obo/UPHENO_0049880
+http://purl.obolibrary.org/obo/GO_0016477	http://purl.obolibrary.org/obo/UPHENO_0049643
+http://purl.obolibrary.org/obo/GO_0009268	http://purl.obolibrary.org/obo/UPHENO_0049881
+http://purl.obolibrary.org/obo/GO_0016358	http://purl.obolibrary.org/obo/UPHENO_0049644
+http://purl.obolibrary.org/obo/GO_0042417	http://purl.obolibrary.org/obo/UPHENO_0049883
+http://purl.obolibrary.org/obo/GO_0009266	http://purl.obolibrary.org/obo/UPHENO_0049885
+http://purl.obolibrary.org/obo/GO_0031175	http://purl.obolibrary.org/obo/UPHENO_0049886
+http://purl.obolibrary.org/obo/GO_0032940	http://purl.obolibrary.org/obo/UPHENO_0049647
+http://purl.obolibrary.org/obo/GO_0007635	http://purl.obolibrary.org/obo/UPHENO_0049648
+http://purl.obolibrary.org/obo/GO_0030534	http://purl.obolibrary.org/obo/UPHENO_0049650
+http://purl.obolibrary.org/obo/GO_0050821	http://purl.obolibrary.org/obo/UPHENO_0049651
+http://purl.obolibrary.org/obo/GO_0043050	http://purl.obolibrary.org/obo/UPHENO_0049653
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+http://purl.obolibrary.org/obo/GO_0048066	http://purl.obolibrary.org/obo/UPHENO_0049891
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+http://purl.obolibrary.org/obo/GO_0007631	http://purl.obolibrary.org/obo/UPHENO_0049664
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+http://purl.obolibrary.org/obo/GO_0006970	http://purl.obolibrary.org/obo/UPHENO_0049681
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+http://purl.obolibrary.org/obo/GO_0007271	http://purl.obolibrary.org/obo/UPHENO_0049915
+http://purl.obolibrary.org/obo/GO_0046959	http://purl.obolibrary.org/obo/UPHENO_0049916
+http://purl.obolibrary.org/obo/GO_0030261	http://purl.obolibrary.org/obo/UPHENO_0049918
+http://purl.obolibrary.org/obo/GO_0031129	http://purl.obolibrary.org/obo/UPHENO_0049920
+http://purl.obolibrary.org/obo/GO_0007019	http://purl.obolibrary.org/obo/UPHENO_0049921
+http://purl.obolibrary.org/obo/GO_0040040	http://purl.obolibrary.org/obo/UPHENO_0049928
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+http://purl.obolibrary.org/obo/GO_1903047	http://purl.obolibrary.org/obo/UPHENO_0049930
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+http://purl.obolibrary.org/obo/GO_0030036	http://purl.obolibrary.org/obo/UPHENO_0049939
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+http://purl.obolibrary.org/obo/GO_0051293	http://purl.obolibrary.org/obo/UPHENO_0049944
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+http://purl.obolibrary.org/obo/GO_1901530	http://purl.obolibrary.org/obo/UPHENO_0049704
+http://purl.obolibrary.org/obo/GO_0007163	http://purl.obolibrary.org/obo/UPHENO_0049950
+http://purl.obolibrary.org/obo/GO_0030728	http://purl.obolibrary.org/obo/UPHENO_0049705
+http://purl.obolibrary.org/obo/GO_0007049	http://purl.obolibrary.org/obo/UPHENO_0049952
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+http://purl.obolibrary.org/obo/GO_0010212	http://purl.obolibrary.org/obo/UPHENO_0049956
+http://purl.obolibrary.org/obo/GO_0034644	http://purl.obolibrary.org/obo/UPHENO_0049957
+http://purl.obolibrary.org/obo/GO_0010332	http://purl.obolibrary.org/obo/UPHENO_0049958
+http://purl.obolibrary.org/obo/GO_0007051	http://purl.obolibrary.org/obo/UPHENO_0049959
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+http://purl.obolibrary.org/obo/GO_0035176	http://purl.obolibrary.org/obo/UPHENO_0049713
+http://purl.obolibrary.org/obo/GO_0033554	http://purl.obolibrary.org/obo/UPHENO_0049964
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+http://purl.obolibrary.org/obo/GO_0007155	http://purl.obolibrary.org/obo/UPHENO_0049969
+http://purl.obolibrary.org/obo/GO_0007276	http://purl.obolibrary.org/obo/UPHENO_0049970
+http://purl.obolibrary.org/obo/GO_0048666	http://purl.obolibrary.org/obo/UPHENO_0049719
+http://purl.obolibrary.org/obo/GO_0007274	http://purl.obolibrary.org/obo/UPHENO_0049971
+http://purl.obolibrary.org/obo/GO_1904356	http://purl.obolibrary.org/obo/UPHENO_0049972
+http://purl.obolibrary.org/obo/GO_0043652	http://purl.obolibrary.org/obo/UPHENO_0049973
+http://purl.obolibrary.org/obo/GO_0040024	http://purl.obolibrary.org/obo/UPHENO_0049974
+http://purl.obolibrary.org/obo/GO_0007399	http://purl.obolibrary.org/obo/UPHENO_0049975
+http://purl.obolibrary.org/obo/GO_0012501	http://purl.obolibrary.org/obo/UPHENO_0049978
+http://purl.obolibrary.org/obo/GO_0040025	http://purl.obolibrary.org/obo/UPHENO_0049980
+http://purl.obolibrary.org/obo/GO_0007040	http://purl.obolibrary.org/obo/UPHENO_0049983
+http://purl.obolibrary.org/obo/GO_0035188	http://purl.obolibrary.org/obo/UPHENO_0049721
+http://purl.obolibrary.org/obo/GO_0007283	http://purl.obolibrary.org/obo/UPHENO_0049985
+http://purl.obolibrary.org/obo/GO_0007281	http://purl.obolibrary.org/obo/UPHENO_0049986
+http://purl.obolibrary.org/obo/GO_0006629	http://purl.obolibrary.org/obo/UPHENO_0049723
+http://purl.obolibrary.org/obo/GO_0000768	http://purl.obolibrary.org/obo/UPHENO_0049988
+http://purl.obolibrary.org/obo/GO_0006259	http://purl.obolibrary.org/obo/UPHENO_0049990
+http://purl.obolibrary.org/obo/GO_0006935	http://purl.obolibrary.org/obo/UPHENO_0049727
+http://purl.obolibrary.org/obo/GO_0000398	http://purl.obolibrary.org/obo/UPHENO_0049728
+http://purl.obolibrary.org/obo/GO_0051301	http://purl.obolibrary.org/obo/UPHENO_0049729
+http://purl.obolibrary.org/obo/GO_0035915	http://purl.obolibrary.org/obo/UPHENO_0049993
+http://purl.obolibrary.org/obo/GO_1903537	http://purl.obolibrary.org/obo/UPHENO_0049730
+http://purl.obolibrary.org/obo/GO_0006260	http://purl.obolibrary.org/obo/UPHENO_0049997
+http://purl.obolibrary.org/obo/GO_0009408	http://purl.obolibrary.org/obo/UPHENO_0049999
+http://purl.obolibrary.org/obo/GO_0072347	http://purl.obolibrary.org/obo/UPHENO_0049737
+http://purl.obolibrary.org/obo/GO_0008306	http://purl.obolibrary.org/obo/UPHENO_0050002
+http://purl.obolibrary.org/obo/GO_0016050	http://purl.obolibrary.org/obo/UPHENO_0050006
+http://purl.obolibrary.org/obo/GO_0048488	http://purl.obolibrary.org/obo/UPHENO_0049741
+http://purl.obolibrary.org/obo/GO_0042023	http://purl.obolibrary.org/obo/UPHENO_0050009
+http://purl.obolibrary.org/obo/GO_0016049	http://purl.obolibrary.org/obo/UPHENO_0050012
+http://purl.obolibrary.org/obo/GO_0036211	http://purl.obolibrary.org/obo/UPHENO_0049744
+http://purl.obolibrary.org/obo/GO_0032094	http://purl.obolibrary.org/obo/UPHENO_0049747
+http://purl.obolibrary.org/obo/GO_0090664	http://purl.obolibrary.org/obo/UPHENO_0050020
+http://purl.obolibrary.org/obo/GO_0022618	http://purl.obolibrary.org/obo/UPHENO_0050023
+http://purl.obolibrary.org/obo/GO_0009636	http://purl.obolibrary.org/obo/UPHENO_0050024
+http://purl.obolibrary.org/obo/GO_0071028	http://purl.obolibrary.org/obo/UPHENO_0049751
+http://purl.obolibrary.org/obo/GO_0008219	http://purl.obolibrary.org/obo/UPHENO_0050027
+http://purl.obolibrary.org/obo/GO_0007369	http://purl.obolibrary.org/obo/UPHENO_0050028
+http://purl.obolibrary.org/obo/GO_0045087	http://purl.obolibrary.org/obo/UPHENO_0049755
+http://purl.obolibrary.org/obo/GO_0071470	http://purl.obolibrary.org/obo/UPHENO_0078651
+http://purl.obolibrary.org/obo/GO_0006396	http://purl.obolibrary.org/obo/UPHENO_0050030
+http://purl.obolibrary.org/obo/GO_0048599	http://purl.obolibrary.org/obo/UPHENO_0049761
+http://purl.obolibrary.org/obo/GO_0034606	http://purl.obolibrary.org/obo/UPHENO_0050032
+http://purl.obolibrary.org/obo/GO_0009791	http://purl.obolibrary.org/obo/UPHENO_0050033
+http://purl.obolibrary.org/obo/GO_0009790	http://purl.obolibrary.org/obo/UPHENO_0050034
+http://purl.obolibrary.org/obo/GO_0034608	http://purl.obolibrary.org/obo/UPHENO_0050035
+http://purl.obolibrary.org/obo/GO_0042133	http://purl.obolibrary.org/obo/UPHENO_0050036
+http://purl.obolibrary.org/obo/GO_0006950	http://purl.obolibrary.org/obo/UPHENO_0049588
+http://purl.obolibrary.org/obo/GO_0051081	http://purl.obolibrary.org/obo/UPHENO_0050039
+http://purl.obolibrary.org/obo/GO_0060465	http://purl.obolibrary.org/obo/UPHENO_0049768
+http://purl.obolibrary.org/obo/GO_0009306	http://purl.obolibrary.org/obo/UPHENO_0050043
+http://purl.obolibrary.org/obo/GO_0001708	http://purl.obolibrary.org/obo/UPHENO_0050044
+http://purl.obolibrary.org/obo/GO_0031573	http://purl.obolibrary.org/obo/UPHENO_0050046
+http://purl.obolibrary.org/obo/GO_0071479	http://purl.obolibrary.org/obo/UPHENO_0049774
+http://purl.obolibrary.org/obo/GO_0016079	http://purl.obolibrary.org/obo/UPHENO_0050047
+http://purl.obolibrary.org/obo/GO_0071480	http://purl.obolibrary.org/obo/UPHENO_0049776
+http://purl.obolibrary.org/obo/GO_0016070	http://purl.obolibrary.org/obo/UPHENO_0050048
+http://purl.obolibrary.org/obo/GO_0016192	http://purl.obolibrary.org/obo/UPHENO_0050050
+http://purl.obolibrary.org/obo/GO_0048468	http://purl.obolibrary.org/obo/UPHENO_0049780
+http://purl.obolibrary.org/obo/GO_0048589	http://purl.obolibrary.org/obo/UPHENO_0049781
+http://purl.obolibrary.org/obo/GO_0065004	http://purl.obolibrary.org/obo/UPHENO_0050052
+http://purl.obolibrary.org/obo/GO_1901562	http://purl.obolibrary.org/obo/UPHENO_0049782
+http://purl.obolibrary.org/obo/GO_0065003	http://purl.obolibrary.org/obo/UPHENO_0050053
+http://purl.obolibrary.org/obo/GO_0034976	http://purl.obolibrary.org/obo/UPHENO_0050055
+http://purl.obolibrary.org/obo/GO_0000280	http://purl.obolibrary.org/obo/UPHENO_0049784
+http://purl.obolibrary.org/obo/GO_0009411	http://purl.obolibrary.org/obo/UPHENO_0050059
+http://purl.obolibrary.org/obo/GO_0061564	http://purl.obolibrary.org/obo/UPHENO_0049786
+http://purl.obolibrary.org/obo/GO_0009416	http://purl.obolibrary.org/obo/UPHENO_0050066
+http://purl.obolibrary.org/obo/GO_0034059	http://purl.obolibrary.org/obo/UPHENO_0049788
+http://purl.obolibrary.org/obo/GO_0007549	http://purl.obolibrary.org/obo/UPHENO_0050071
+http://purl.obolibrary.org/obo/GO_0042073	http://purl.obolibrary.org/obo/UPHENO_0050072
+http://purl.obolibrary.org/obo/GO_0060280	http://purl.obolibrary.org/obo/UPHENO_0049792
+http://purl.obolibrary.org/obo/GO_0010037	http://purl.obolibrary.org/obo/UPHENO_0049797
+http://purl.obolibrary.org/obo/GO_0000910	http://purl.obolibrary.org/obo/UPHENO_0050076
+http://purl.obolibrary.org/obo/GO_0044819	http://purl.obolibrary.org/obo/UPHENO_0049806
+http://purl.obolibrary.org/obo/GO_0044818	http://purl.obolibrary.org/obo/UPHENO_0049807
+http://purl.obolibrary.org/obo/GO_0030421	http://purl.obolibrary.org/obo/UPHENO_0050078
+http://purl.obolibrary.org/obo/GO_0009605	http://purl.obolibrary.org/obo/UPHENO_0050079
+http://purl.obolibrary.org/obo/GO_0000226	http://purl.obolibrary.org/obo/UPHENO_0049808
+http://purl.obolibrary.org/obo/GO_0007416	http://purl.obolibrary.org/obo/UPHENO_0050082
+http://purl.obolibrary.org/obo/GO_0007413	http://purl.obolibrary.org/obo/UPHENO_0050083
+http://purl.obolibrary.org/obo/GO_0046785	http://purl.obolibrary.org/obo/UPHENO_0050088
+http://purl.obolibrary.org/obo/GO_0007097	http://purl.obolibrary.org/obo/UPHENO_0049810
+http://purl.obolibrary.org/obo/GO_0097091	http://purl.obolibrary.org/obo/UPHENO_0050090
+http://purl.obolibrary.org/obo/GO_0007411	http://purl.obolibrary.org/obo/UPHENO_0050092
+http://purl.obolibrary.org/obo/GO_0007530	http://purl.obolibrary.org/obo/UPHENO_0050096
+http://purl.obolibrary.org/obo/GO_0034599	http://purl.obolibrary.org/obo/UPHENO_0078652
+http://purl.obolibrary.org/obo/GO_0010269	http://purl.obolibrary.org/obo/UPHENO_0049811
+http://purl.obolibrary.org/obo/GO_0060179	http://purl.obolibrary.org/obo/UPHENO_0049815
+http://purl.obolibrary.org/obo/GO_0051452	http://purl.obolibrary.org/obo/UPHENO_0049817
+http://purl.obolibrary.org/obo/GO_0072710	http://purl.obolibrary.org/obo/UPHENO_0050105
+http://purl.obolibrary.org/obo/GO_0006479	http://purl.obolibrary.org/obo/UPHENO_0050107
+http://purl.obolibrary.org/obo/GO_0032502	http://purl.obolibrary.org/obo/UPHENO_0050108
+http://purl.obolibrary.org/obo/GO_0006914	http://purl.obolibrary.org/obo/UPHENO_0049824
+http://purl.obolibrary.org/obo/GO_1990840	http://purl.obolibrary.org/obo/UPHENO_0050110
+http://purl.obolibrary.org/obo/GO_0050919	http://purl.obolibrary.org/obo/UPHENO_0050111
+http://purl.obolibrary.org/obo/GO_0050918	http://purl.obolibrary.org/obo/UPHENO_0050112
+http://purl.obolibrary.org/obo/GO_0051321	http://purl.obolibrary.org/obo/UPHENO_0078653
+http://purl.obolibrary.org/obo/GO_0009629	http://purl.obolibrary.org/obo/UPHENO_0080604
+http://purl.obolibrary.org/obo/GO_0006915	http://purl.obolibrary.org/obo/UPHENO_0049831
+http://purl.obolibrary.org/obo/GO_0055001	http://purl.obolibrary.org/obo/UPHENO_0050120
+http://purl.obolibrary.org/obo/GO_0008406	http://purl.obolibrary.org/obo/UPHENO_0050123
+http://purl.obolibrary.org/obo/GO_0006468	http://purl.obolibrary.org/obo/UPHENO_0050125
+http://purl.obolibrary.org/obo/GO_0009058	http://purl.obolibrary.org/obo/UPHENO_0049835
+http://purl.obolibrary.org/obo/GO_0042048	http://purl.obolibrary.org/obo/UPHENO_0050130
+http://purl.obolibrary.org/obo/GO_0019538	http://purl.obolibrary.org/obo/UPHENO_0050131
+http://purl.obolibrary.org/obo/GO_0010288	http://purl.obolibrary.org/obo/UPHENO_0049838
+http://purl.obolibrary.org/obo/GO_0009611	http://purl.obolibrary.org/obo/UPHENO_0050133
+http://purl.obolibrary.org/obo/GO_0010042	http://purl.obolibrary.org/obo/UPHENO_0049840
+http://purl.obolibrary.org/obo/GO_0010165	http://purl.obolibrary.org/obo/UPHENO_0049842
+http://purl.obolibrary.org/obo/GO_0010044	http://purl.obolibrary.org/obo/UPHENO_0049843
+http://purl.obolibrary.org/obo/GO_0051310	http://purl.obolibrary.org/obo/UPHENO_0049845
diff --git a/src/curation/upheno-fillers/wbphenotype/abnormalBiologicalProcessInLocation.tsv b/src/curation/upheno-fillers/wbphenotype/abnormalBiologicalProcessInLocation.tsv
new file mode 100644
index 00000000..a302e4af
--- /dev/null
+++ b/src/curation/upheno-fillers/wbphenotype/abnormalBiologicalProcessInLocation.tsv
@@ -0,0 +1,5 @@
+biological_process	location	defined_class
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/GO_0005783	http://purl.obolibrary.org/obo/UPHENO_0059882
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/GO_0043226	http://purl.obolibrary.org/obo/UPHENO_0059928
+http://purl.obolibrary.org/obo/GO_0008152	http://purl.obolibrary.org/obo/GO_0043226	http://purl.obolibrary.org/obo/UPHENO_0059931
+http://purl.obolibrary.org/obo/GO_0008152	http://purl.obolibrary.org/obo/GO_0005783	http://purl.obolibrary.org/obo/UPHENO_0059908
diff --git a/src/curation/upheno-fillers/wbphenotype/abnormalCellProliferationInAnatomicalEntity.tsv b/src/curation/upheno-fillers/wbphenotype/abnormalCellProliferationInAnatomicalEntity.tsv
new file mode 100644
index 00000000..53687e69
--- /dev/null
+++ b/src/curation/upheno-fillers/wbphenotype/abnormalCellProliferationInAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0054392
diff --git a/src/curation/upheno-fillers/wbphenotype/abnormalCellularComponent.tsv b/src/curation/upheno-fillers/wbphenotype/abnormalCellularComponent.tsv
new file mode 100644
index 00000000..f52474d5
--- /dev/null
+++ b/src/curation/upheno-fillers/wbphenotype/abnormalCellularComponent.tsv
@@ -0,0 +1,4 @@
+cellular_component	defined_class
+http://purl.obolibrary.org/obo/GO_0005575	http://purl.obolibrary.org/obo/UPHENO_0006889
+http://purl.obolibrary.org/obo/GO_0005643	http://purl.obolibrary.org/obo/UPHENO_0082545
+http://purl.obolibrary.org/obo/GO_0005912	http://purl.obolibrary.org/obo/UPHENO_0082546
diff --git a/src/curation/upheno-fillers/wbphenotype/abnormalCoilingOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/wbphenotype/abnormalCoilingOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..d7fc165c
--- /dev/null
+++ b/src/curation/upheno-fillers/wbphenotype/abnormalCoilingOfAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0078441
diff --git a/src/curation/upheno-fillers/wbphenotype/abnormalDegenerationOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/wbphenotype/abnormalDegenerationOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..45d81bb0
--- /dev/null
+++ b/src/curation/upheno-fillers/wbphenotype/abnormalDegenerationOfAnatomicalEntity.tsv
@@ -0,0 +1,3 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0073937
+http://purl.obolibrary.org/obo/GO_0030424	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/wbphenotype/abnormalDegenerationOfCellularComponent.tsv b/src/curation/upheno-fillers/wbphenotype/abnormalDegenerationOfCellularComponent.tsv
new file mode 100644
index 00000000..9025391d
--- /dev/null
+++ b/src/curation/upheno-fillers/wbphenotype/abnormalDegenerationOfCellularComponent.tsv
@@ -0,0 +1,3 @@
+cellular_component	defined_class
+http://purl.obolibrary.org/obo/GO_0005575	http://purl.obolibrary.org/obo/UPHENO_0079505
+http://purl.obolibrary.org/obo/GO_0030424	http://purl.obolibrary.org/obo/UPHENO_0079524
diff --git a/src/curation/upheno-fillers/wbphenotype/abnormalDevelopmentOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/wbphenotype/abnormalDevelopmentOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..6c308ac7
--- /dev/null
+++ b/src/curation/upheno-fillers/wbphenotype/abnormalDevelopmentOfAnatomicalEntity.tsv
@@ -0,0 +1,6 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0081436
+http://purl.obolibrary.org/obo/UBERON_0002606	http://purl.obolibrary.org/obo/UPHENO_0081437
+http://purl.obolibrary.org/obo/GO_0036194	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0031012	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0044840	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/wbphenotype/abnormalLevelOfChemicalEntity.tsv b/src/curation/upheno-fillers/wbphenotype/abnormalLevelOfChemicalEntity.tsv
new file mode 100644
index 00000000..0fd37d77
--- /dev/null
+++ b/src/curation/upheno-fillers/wbphenotype/abnormalLevelOfChemicalEntity.tsv
@@ -0,0 +1,9 @@
+chemical_entity	defined_class
+http://purl.obolibrary.org/obo/CHEBI_30413	http://purl.obolibrary.org/obo/UPHENO_0077201
+http://purl.obolibrary.org/obo/CHEBI_15422	http://purl.obolibrary.org/obo/UPHENO_0077202
+http://purl.obolibrary.org/obo/CHEBI_16865	http://purl.obolibrary.org/obo/UPHENO_0046335
+http://purl.obolibrary.org/obo/CHEBI_24431	http://purl.obolibrary.org/obo/UPHENO_0046284
+http://purl.obolibrary.org/obo/CHEBI_16856	http://purl.obolibrary.org/obo/UPHENO_0046353
+http://purl.obolibrary.org/obo/CHEBI_28087	http://purl.obolibrary.org/obo/UPHENO_0046300
+http://purl.obolibrary.org/obo/CHEBI_18059	http://purl.obolibrary.org/obo/UPHENO_0046281
+http://purl.obolibrary.org/obo/CHEBI_15355	http://purl.obolibrary.org/obo/UPHENO_0046376
diff --git a/src/curation/upheno-fillers/wbphenotype/abnormalMolecularFunction.tsv b/src/curation/upheno-fillers/wbphenotype/abnormalMolecularFunction.tsv
new file mode 100644
index 00000000..d1a641e6
--- /dev/null
+++ b/src/curation/upheno-fillers/wbphenotype/abnormalMolecularFunction.tsv
@@ -0,0 +1,4 @@
+molecular_function	defined_class
+http://purl.obolibrary.org/obo/GO_0003824	http://purl.obolibrary.org/obo/UPHENO_0031742
+http://purl.obolibrary.org/obo/GO_0003674	http://purl.obolibrary.org/obo/UPHENO_0031743
+http://purl.obolibrary.org/obo/GO_0016757	http://purl.obolibrary.org/obo/UPHENO_0031744
diff --git a/src/curation/upheno-fillers/wbphenotype/abnormalMorphologyOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/wbphenotype/abnormalMorphologyOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..8d7a247d
--- /dev/null
+++ b/src/curation/upheno-fillers/wbphenotype/abnormalMorphologyOfAnatomicalEntity.tsv
@@ -0,0 +1,45 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/GO_0031982	http://purl.obolibrary.org/obo/UPHENO_0085904
+http://purl.obolibrary.org/obo/GO_0055037	http://purl.obolibrary.org/obo/UPHENO_0085905
+http://purl.obolibrary.org/obo/GO_0030054	http://purl.obolibrary.org/obo/UPHENO_0085906
+http://purl.obolibrary.org/obo/GO_0005739	http://purl.obolibrary.org/obo/UPHENO_0085592
+http://purl.obolibrary.org/obo/GO_0005739	http://purl.obolibrary.org/obo/UPHENO_0085592
+http://purl.obolibrary.org/obo/GO_0000781	http://purl.obolibrary.org/obo/UPHENO_0085870
+http://purl.obolibrary.org/obo/GO_0005911	http://purl.obolibrary.org/obo/UPHENO_0085907
+http://purl.obolibrary.org/obo/GO_0005930	http://purl.obolibrary.org/obo/UPHENO_0085908
+http://purl.obolibrary.org/obo/GO_0005634	http://purl.obolibrary.org/obo/UPHENO_0077863
+http://purl.obolibrary.org/obo/GO_0005634	http://purl.obolibrary.org/obo/UPHENO_0077863
+http://purl.obolibrary.org/obo/GO_0031965	http://purl.obolibrary.org/obo/UPHENO_0077864
+http://purl.obolibrary.org/obo/GO_0005777	http://purl.obolibrary.org/obo/UPHENO_0085649
+http://purl.obolibrary.org/obo/GO_0005730	http://purl.obolibrary.org/obo/UPHENO_0085594
+http://purl.obolibrary.org/obo/GO_0005794	http://purl.obolibrary.org/obo/UPHENO_0085716
+http://purl.obolibrary.org/obo/GO_0005770	http://purl.obolibrary.org/obo/UPHENO_0085909
+http://purl.obolibrary.org/obo/GO_0005694	http://purl.obolibrary.org/obo/UPHENO_0085690
+http://purl.obolibrary.org/obo/GO_0044840	http://purl.obolibrary.org/obo/UPHENO_0085910
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/GO_0060107	http://purl.obolibrary.org/obo/UPHENO_0085911
+http://purl.obolibrary.org/obo/GO_0060109	http://purl.obolibrary.org/obo/UPHENO_0085912
+http://purl.obolibrary.org/obo/GO_0005929	http://purl.obolibrary.org/obo/UPHENO_0077865
+http://purl.obolibrary.org/obo/GO_0005929	http://purl.obolibrary.org/obo/UPHENO_0077865
+http://purl.obolibrary.org/obo/GO_0031012	http://purl.obolibrary.org/obo/UPHENO_0085823
+http://purl.obolibrary.org/obo/GO_0000932	http://purl.obolibrary.org/obo/UPHENO_0085913
+http://purl.obolibrary.org/obo/GO_0005604	http://purl.obolibrary.org/obo/UPHENO_0085635
+http://purl.obolibrary.org/obo/GO_0005769	http://purl.obolibrary.org/obo/UPHENO_0085914
+http://purl.obolibrary.org/obo/GO_0005768	http://purl.obolibrary.org/obo/UPHENO_0085915
+http://purl.obolibrary.org/obo/GO_0030424	http://purl.obolibrary.org/obo/UPHENO_0077861
+http://purl.obolibrary.org/obo/GO_0030424	http://purl.obolibrary.org/obo/UPHENO_0077861
+http://purl.obolibrary.org/obo/GO_0005886	http://purl.obolibrary.org/obo/UPHENO_0077862
+http://purl.obolibrary.org/obo/GO_0005886	http://purl.obolibrary.org/obo/UPHENO_0077862
+http://purl.obolibrary.org/obo/GO_0030425	http://purl.obolibrary.org/obo/UPHENO_0085758
+http://purl.obolibrary.org/obo/GO_0070160	http://purl.obolibrary.org/obo/UPHENO_0085916
+http://purl.obolibrary.org/obo/GO_0005884	http://purl.obolibrary.org/obo/UPHENO_0085917
+http://purl.obolibrary.org/obo/GO_0005764	http://purl.obolibrary.org/obo/UPHENO_0085685
+http://purl.obolibrary.org/obo/GO_0005783	http://purl.obolibrary.org/obo/UPHENO_0085665
+http://purl.obolibrary.org/obo/GO_0043005	http://purl.obolibrary.org/obo/UPHENO_0077866
+http://purl.obolibrary.org/obo/GO_0043005	http://purl.obolibrary.org/obo/UPHENO_0077866
+http://purl.obolibrary.org/obo/GO_0045202	http://purl.obolibrary.org/obo/UPHENO_0077867
+http://purl.obolibrary.org/obo/GO_0045202	http://purl.obolibrary.org/obo/UPHENO_0077867
+http://purl.obolibrary.org/obo/GO_0043186	http://purl.obolibrary.org/obo/UPHENO_0085918
diff --git a/src/curation/upheno-fillers/wbphenotype/abnormalMorphologyOfAnatomicalEntityInLocation.tsv b/src/curation/upheno-fillers/wbphenotype/abnormalMorphologyOfAnatomicalEntityInLocation.tsv
new file mode 100644
index 00000000..b7121acc
--- /dev/null
+++ b/src/curation/upheno-fillers/wbphenotype/abnormalMorphologyOfAnatomicalEntityInLocation.tsv
@@ -0,0 +1 @@
+anatomical_entity	location	defined_class
diff --git a/src/curation/upheno-fillers/wbphenotype/abnormalMorphologyOfCellularComponent.tsv b/src/curation/upheno-fillers/wbphenotype/abnormalMorphologyOfCellularComponent.tsv
new file mode 100644
index 00000000..4dd99cb1
--- /dev/null
+++ b/src/curation/upheno-fillers/wbphenotype/abnormalMorphologyOfCellularComponent.tsv
@@ -0,0 +1,35 @@
+cellular_component	defined_class
+http://purl.obolibrary.org/obo/GO_0005794	http://purl.obolibrary.org/obo/UPHENO_0067642
+http://purl.obolibrary.org/obo/GO_0005575	http://purl.obolibrary.org/obo/UPHENO_0067691
+http://purl.obolibrary.org/obo/GO_0005770	http://purl.obolibrary.org/obo/UPHENO_0067736
+http://purl.obolibrary.org/obo/GO_0005694	http://purl.obolibrary.org/obo/UPHENO_0067694
+http://purl.obolibrary.org/obo/GO_0044840	http://purl.obolibrary.org/obo/UPHENO_0067737
+http://purl.obolibrary.org/obo/GO_0005930	http://purl.obolibrary.org/obo/UPHENO_0067738
+http://purl.obolibrary.org/obo/GO_0005634	http://purl.obolibrary.org/obo/UPHENO_0067645
+http://purl.obolibrary.org/obo/GO_0031965	http://purl.obolibrary.org/obo/UPHENO_0067739
+http://purl.obolibrary.org/obo/GO_0005777	http://purl.obolibrary.org/obo/UPHENO_0067699
+http://purl.obolibrary.org/obo/GO_0005730	http://purl.obolibrary.org/obo/UPHENO_0067701
+http://purl.obolibrary.org/obo/GO_0000781	http://purl.obolibrary.org/obo/UPHENO_0067651
+http://purl.obolibrary.org/obo/GO_0005911	http://purl.obolibrary.org/obo/UPHENO_0067740
+http://purl.obolibrary.org/obo/GO_0030054	http://purl.obolibrary.org/obo/UPHENO_0067741
+http://purl.obolibrary.org/obo/GO_0005739	http://purl.obolibrary.org/obo/UPHENO_0067707
+http://purl.obolibrary.org/obo/GO_0031982	http://purl.obolibrary.org/obo/UPHENO_0067742
+http://purl.obolibrary.org/obo/GO_0055037	http://purl.obolibrary.org/obo/UPHENO_0067743
+http://purl.obolibrary.org/obo/GO_0043186	http://purl.obolibrary.org/obo/UPHENO_0067744
+http://purl.obolibrary.org/obo/GO_0005783	http://purl.obolibrary.org/obo/UPHENO_0067712
+http://purl.obolibrary.org/obo/GO_0043005	http://purl.obolibrary.org/obo/UPHENO_0067664
+http://purl.obolibrary.org/obo/GO_0045202	http://purl.obolibrary.org/obo/UPHENO_0067713
+http://purl.obolibrary.org/obo/GO_0030424	http://purl.obolibrary.org/obo/UPHENO_0067666
+http://purl.obolibrary.org/obo/GO_0005886	http://purl.obolibrary.org/obo/UPHENO_0067668
+http://purl.obolibrary.org/obo/GO_0030425	http://purl.obolibrary.org/obo/UPHENO_0067669
+http://purl.obolibrary.org/obo/GO_0070160	http://purl.obolibrary.org/obo/UPHENO_0067745
+http://purl.obolibrary.org/obo/GO_0005884	http://purl.obolibrary.org/obo/UPHENO_0067746
+http://purl.obolibrary.org/obo/GO_0005764	http://purl.obolibrary.org/obo/UPHENO_0067671
+http://purl.obolibrary.org/obo/GO_0005604	http://purl.obolibrary.org/obo/UPHENO_0067672
+http://purl.obolibrary.org/obo/GO_0005769	http://purl.obolibrary.org/obo/UPHENO_0067747
+http://purl.obolibrary.org/obo/GO_0005768	http://purl.obolibrary.org/obo/UPHENO_0067748
+http://purl.obolibrary.org/obo/GO_0000932	http://purl.obolibrary.org/obo/UPHENO_0067749
+http://purl.obolibrary.org/obo/GO_0060109	http://purl.obolibrary.org/obo/UPHENO_0067750
+http://purl.obolibrary.org/obo/GO_0005929	http://purl.obolibrary.org/obo/UPHENO_0067683
+http://purl.obolibrary.org/obo/GO_0031012	http://purl.obolibrary.org/obo/UPHENO_0067718
+http://purl.obolibrary.org/obo/GO_0060107	http://purl.obolibrary.org/obo/UPHENO_0067751
diff --git a/src/curation/upheno-fillers/wbphenotype/abnormalMorphologyOfPartOfAnatomicalEntity-modified.tsv b/src/curation/upheno-fillers/wbphenotype/abnormalMorphologyOfPartOfAnatomicalEntity-modified.tsv
new file mode 100644
index 00000000..6c847ca9
--- /dev/null
+++ b/src/curation/upheno-fillers/wbphenotype/abnormalMorphologyOfPartOfAnatomicalEntity-modified.tsv
@@ -0,0 +1,35 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/GO_0031982	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0055037	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0030054	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0005739	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0000781	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0005911	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0005930	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0005634	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0031965	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0005777	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0005730	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0005794	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0005770	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0005694	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0044840	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0060107	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0060109	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0005929	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0031012	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0000932	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0005604	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0005769	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0005768	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0030424	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0005886	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0030425	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0070160	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0005884	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0005764	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0005783	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0043005	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0045202	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0043186	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/wbphenotype/abnormalMorphologyOfPartOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/wbphenotype/abnormalMorphologyOfPartOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..ca3ba71f
--- /dev/null
+++ b/src/curation/upheno-fillers/wbphenotype/abnormalMorphologyOfPartOfAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0076692
diff --git a/src/curation/upheno-fillers/wbphenotype/abnormalNumberOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/wbphenotype/abnormalNumberOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..095ed03d
--- /dev/null
+++ b/src/curation/upheno-fillers/wbphenotype/abnormalNumberOfAnatomicalEntity.tsv
@@ -0,0 +1,4 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0011498
+http://purl.obolibrary.org/obo/GO_0031982	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0008021	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/wbphenotype/abnormalNumberOfCellularComponent.tsv b/src/curation/upheno-fillers/wbphenotype/abnormalNumberOfCellularComponent.tsv
new file mode 100644
index 00000000..229515af
--- /dev/null
+++ b/src/curation/upheno-fillers/wbphenotype/abnormalNumberOfCellularComponent.tsv
@@ -0,0 +1,4 @@
+cellular_component	defined_class
+http://purl.obolibrary.org/obo/GO_0008021	http://purl.obolibrary.org/obo/UPHENO_0077337
+http://purl.obolibrary.org/obo/GO_0031982	http://purl.obolibrary.org/obo/UPHENO_0077417
+http://purl.obolibrary.org/obo/GO_0005575	http://purl.obolibrary.org/obo/UPHENO_0046183
diff --git a/src/curation/upheno-fillers/wbphenotype/abnormalPigmentationOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/wbphenotype/abnormalPigmentationOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..9043ea08
--- /dev/null
+++ b/src/curation/upheno-fillers/wbphenotype/abnormalPigmentationOfAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0066794
diff --git a/src/curation/upheno-fillers/wbphenotype/abnormalPositionOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/wbphenotype/abnormalPositionOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..482af129
--- /dev/null
+++ b/src/curation/upheno-fillers/wbphenotype/abnormalPositionOfAnatomicalEntity.tsv
@@ -0,0 +1,3 @@
+entity	defined_class
+http://purl.obolibrary.org/obo/GO_0005739	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0018390
diff --git a/src/curation/upheno-fillers/wbphenotype/abnormalPositionOfAnatomicalEntityInLocation.tsv b/src/curation/upheno-fillers/wbphenotype/abnormalPositionOfAnatomicalEntityInLocation.tsv
new file mode 100644
index 00000000..b7121acc
--- /dev/null
+++ b/src/curation/upheno-fillers/wbphenotype/abnormalPositionOfAnatomicalEntityInLocation.tsv
@@ -0,0 +1 @@
+anatomical_entity	location	defined_class
diff --git a/src/curation/upheno-fillers/wbphenotype/abnormalRateOfBiologicalProcess.tsv b/src/curation/upheno-fillers/wbphenotype/abnormalRateOfBiologicalProcess.tsv
new file mode 100644
index 00000000..18c99e1c
--- /dev/null
+++ b/src/curation/upheno-fillers/wbphenotype/abnormalRateOfBiologicalProcess.tsv
@@ -0,0 +1,4 @@
+biological_process	defined_class
+http://purl.obolibrary.org/obo/GO_0032502	http://purl.obolibrary.org/obo/UPHENO_0080382
+http://purl.obolibrary.org/obo/GO_0043050	http://purl.obolibrary.org/obo/UPHENO_0080383
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UPHENO_0080377
diff --git a/src/curation/upheno-fillers/wbphenotype/abnormalShapeOfAnatomicalEntityByShapeType.tsv b/src/curation/upheno-fillers/wbphenotype/abnormalShapeOfAnatomicalEntityByShapeType.tsv
new file mode 100644
index 00000000..f194832f
--- /dev/null
+++ b/src/curation/upheno-fillers/wbphenotype/abnormalShapeOfAnatomicalEntityByShapeType.tsv
@@ -0,0 +1,5 @@
+entity	shape	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0000411	http://purl.obolibrary.org/obo/UPHENO_0041181
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0041226
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0000617	http://purl.obolibrary.org/obo/UPHENO_0041234
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0000404	http://purl.obolibrary.org/obo/UPHENO_0041206
diff --git a/src/curation/upheno-fillers/wbphenotype/abnormalSpatialPatternOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/wbphenotype/abnormalSpatialPatternOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..f7eca072
--- /dev/null
+++ b/src/curation/upheno-fillers/wbphenotype/abnormalSpatialPatternOfAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0080369
diff --git a/src/curation/upheno-fillers/wbphenotype/abnormallyArrestedBiologicalProcess.tsv b/src/curation/upheno-fillers/wbphenotype/abnormallyArrestedBiologicalProcess.tsv
new file mode 100644
index 00000000..f793331a
--- /dev/null
+++ b/src/curation/upheno-fillers/wbphenotype/abnormallyArrestedBiologicalProcess.tsv
@@ -0,0 +1,6 @@
+biological_process	defined_class
+http://purl.obolibrary.org/obo/GO_0040025	http://purl.obolibrary.org/obo/UPHENO_0018649
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UPHENO_0018635
+http://purl.obolibrary.org/obo/GO_0006915	http://purl.obolibrary.org/obo/UPHENO_0018650
+http://purl.obolibrary.org/obo/GO_0009790	http://purl.obolibrary.org/obo/UPHENO_0018644
+http://purl.obolibrary.org/obo/GO_0007049	http://purl.obolibrary.org/obo/UPHENO_0018645
diff --git a/src/curation/upheno-fillers/wbphenotype/abnormallyBentAnatomicalEntity.tsv b/src/curation/upheno-fillers/wbphenotype/abnormallyBentAnatomicalEntity.tsv
new file mode 100644
index 00000000..39b4985e
--- /dev/null
+++ b/src/curation/upheno-fillers/wbphenotype/abnormallyBentAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0074399
diff --git a/src/curation/upheno-fillers/wbphenotype/abnormallyDecreasedFunctionalityOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/wbphenotype/abnormallyDecreasedFunctionalityOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..cdfac1d0
--- /dev/null
+++ b/src/curation/upheno-fillers/wbphenotype/abnormallyDecreasedFunctionalityOfAnatomicalEntity.tsv
@@ -0,0 +1,3 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0066927
+http://purl.obolibrary.org/obo/GO_0072687	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/wbphenotype/abnormallyDecreasedLengthOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/wbphenotype/abnormallyDecreasedLengthOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..052a780a
--- /dev/null
+++ b/src/curation/upheno-fillers/wbphenotype/abnormallyDecreasedLengthOfAnatomicalEntity.tsv
@@ -0,0 +1,5 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0046505
+http://purl.obolibrary.org/obo/GO_0030424	http://purl.obolibrary.org/obo/UPHENO_0079241
+http://purl.obolibrary.org/obo/GO_0005930	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0030425	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/wbphenotype/abnormallyDecreasedLevelOfChemicalEntity.tsv b/src/curation/upheno-fillers/wbphenotype/abnormallyDecreasedLevelOfChemicalEntity.tsv
new file mode 100644
index 00000000..500bf84c
--- /dev/null
+++ b/src/curation/upheno-fillers/wbphenotype/abnormallyDecreasedLevelOfChemicalEntity.tsv
@@ -0,0 +1,11 @@
+chemical_entity	defined_class
+http://purl.obolibrary.org/obo/CHEBI_30413	http://purl.obolibrary.org/obo/UPHENO_0080018
+http://purl.obolibrary.org/obo/CHEBI_33699	http://purl.obolibrary.org/obo/UPHENO_0066791
+http://purl.obolibrary.org/obo/CHEBI_26523	http://purl.obolibrary.org/obo/UPHENO_0080019
+http://purl.obolibrary.org/obo/CHEBI_15422	http://purl.obolibrary.org/obo/UPHENO_0066792
+http://purl.obolibrary.org/obo/CHEBI_24431	http://purl.obolibrary.org/obo/UPHENO_0066739
+http://purl.obolibrary.org/obo/CHEBI_27363	http://purl.obolibrary.org/obo/UPHENO_0080020
+http://purl.obolibrary.org/obo/CHEBI_16240	http://purl.obolibrary.org/obo/UPHENO_0080021
+http://purl.obolibrary.org/obo/CHEBI_18059	http://purl.obolibrary.org/obo/UPHENO_0066793
+http://purl.obolibrary.org/obo/CHEBI_18248	http://purl.obolibrary.org/obo/UPHENO_0081723
+http://purl.obolibrary.org/obo/CHEBI_26034	http://purl.obolibrary.org/obo/UPHENO_0080022
diff --git a/src/curation/upheno-fillers/wbphenotype/abnormallyDecreasedLevelOfChemicalEntityInLocation.tsv b/src/curation/upheno-fillers/wbphenotype/abnormallyDecreasedLevelOfChemicalEntityInLocation.tsv
new file mode 100644
index 00000000..b25d5c27
--- /dev/null
+++ b/src/curation/upheno-fillers/wbphenotype/abnormallyDecreasedLevelOfChemicalEntityInLocation.tsv
@@ -0,0 +1,3 @@
+chemical_entity	location	defined_class
+http://purl.obolibrary.org/obo/CHEBI_24431	http://purl.obolibrary.org/obo/GO_0005829	http://purl.obolibrary.org/obo/UPHENO_0083912
+http://purl.obolibrary.org/obo/CHEBI_29108	http://purl.obolibrary.org/obo/GO_0005829	http://purl.obolibrary.org/obo/UPHENO_0083913
diff --git a/src/curation/upheno-fillers/wbphenotype/abnormallyDecreasedNumberOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/wbphenotype/abnormallyDecreasedNumberOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..c057f89c
--- /dev/null
+++ b/src/curation/upheno-fillers/wbphenotype/abnormallyDecreasedNumberOfAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0063722
diff --git a/src/curation/upheno-fillers/wbphenotype/abnormallyDecreasedOccurrenceOfBiologicalProcess.tsv b/src/curation/upheno-fillers/wbphenotype/abnormallyDecreasedOccurrenceOfBiologicalProcess.tsv
new file mode 100644
index 00000000..719ad281
--- /dev/null
+++ b/src/curation/upheno-fillers/wbphenotype/abnormallyDecreasedOccurrenceOfBiologicalProcess.tsv
@@ -0,0 +1,6 @@
+biological_process	defined_class
+http://purl.obolibrary.org/obo/GO_0000423	http://purl.obolibrary.org/obo/UPHENO_0077427
+http://purl.obolibrary.org/obo/GO_0008219	http://purl.obolibrary.org/obo/UPHENO_0082838
+http://purl.obolibrary.org/obo/GO_0008283	http://purl.obolibrary.org/obo/UPHENO_0077428
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UPHENO_0077429
+http://purl.obolibrary.org/obo/GO_0006915	http://purl.obolibrary.org/obo/UPHENO_0077430
diff --git a/src/curation/upheno-fillers/wbphenotype/abnormallyDecreasedRateOfBiologicalProcess.tsv b/src/curation/upheno-fillers/wbphenotype/abnormallyDecreasedRateOfBiologicalProcess.tsv
new file mode 100644
index 00000000..4822367c
--- /dev/null
+++ b/src/curation/upheno-fillers/wbphenotype/abnormallyDecreasedRateOfBiologicalProcess.tsv
@@ -0,0 +1,12 @@
+biological_process	defined_class
+http://purl.obolibrary.org/obo/GO_0060756	http://purl.obolibrary.org/obo/UPHENO_0005674
+http://purl.obolibrary.org/obo/GO_0032502	http://purl.obolibrary.org/obo/UPHENO_0005597
+http://purl.obolibrary.org/obo/GO_0043050	http://purl.obolibrary.org/obo/UPHENO_0005672
+http://purl.obolibrary.org/obo/GO_0040007	http://purl.obolibrary.org/obo/UPHENO_0005431
+http://purl.obolibrary.org/obo/GO_0051301	http://purl.obolibrary.org/obo/UPHENO_0005655
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UPHENO_0005433
+http://purl.obolibrary.org/obo/GO_0042073	http://purl.obolibrary.org/obo/UPHENO_0005656
+http://purl.obolibrary.org/obo/GO_0048511	http://purl.obolibrary.org/obo/UPHENO_0005442
+http://purl.obolibrary.org/obo/GO_0018991	http://purl.obolibrary.org/obo/UPHENO_0005659
+http://purl.obolibrary.org/obo/GO_0009790	http://purl.obolibrary.org/obo/UPHENO_0005642
+http://purl.obolibrary.org/obo/GO_0040011	http://purl.obolibrary.org/obo/UPHENO_0005413
diff --git a/src/curation/upheno-fillers/wbphenotype/abnormallyDecreasedRateOfMolecularFunction.tsv b/src/curation/upheno-fillers/wbphenotype/abnormallyDecreasedRateOfMolecularFunction.tsv
new file mode 100644
index 00000000..0556233a
--- /dev/null
+++ b/src/curation/upheno-fillers/wbphenotype/abnormallyDecreasedRateOfMolecularFunction.tsv
@@ -0,0 +1,3 @@
+molecular_function	defined_class
+http://purl.obolibrary.org/obo/GO_0003824	http://purl.obolibrary.org/obo/UPHENO_0066897
+http://purl.obolibrary.org/obo/GO_0003674	http://purl.obolibrary.org/obo/UPHENO_0066865
diff --git a/src/curation/upheno-fillers/wbphenotype/abnormallyDecreasedResistanceOfWholeOrganismToChemicalEntity.tsv b/src/curation/upheno-fillers/wbphenotype/abnormallyDecreasedResistanceOfWholeOrganismToChemicalEntity.tsv
new file mode 100644
index 00000000..aaac1afc
--- /dev/null
+++ b/src/curation/upheno-fillers/wbphenotype/abnormallyDecreasedResistanceOfWholeOrganismToChemicalEntity.tsv
@@ -0,0 +1,45 @@
+chemical_entity	defined_class
+http://purl.obolibrary.org/obo/CHEBI_23359	http://purl.obolibrary.org/obo/UPHENO_0076309
+http://purl.obolibrary.org/obo/CHEBI_27638	http://purl.obolibrary.org/obo/UPHENO_0076310
+http://purl.obolibrary.org/obo/CHEBI_25016	http://purl.obolibrary.org/obo/UPHENO_0076311
+http://purl.obolibrary.org/obo/CHEBI_25255	http://purl.obolibrary.org/obo/UPHENO_0076312
+http://purl.obolibrary.org/obo/CHEBI_34905	http://purl.obolibrary.org/obo/UPHENO_0076313
+http://purl.obolibrary.org/obo/CHEBI_29699	http://purl.obolibrary.org/obo/UPHENO_0076314
+http://purl.obolibrary.org/obo/CHEBI_25195	http://purl.obolibrary.org/obo/UPHENO_0076315
+http://purl.obolibrary.org/obo/CHEBI_2814	http://purl.obolibrary.org/obo/UPHENO_0076316
+http://purl.obolibrary.org/obo/CHEBI_33216	http://purl.obolibrary.org/obo/UPHENO_0076317
+http://purl.obolibrary.org/obo/CHEBI_37415	http://purl.obolibrary.org/obo/UPHENO_0076318
+http://purl.obolibrary.org/obo/CHEBI_16236	http://purl.obolibrary.org/obo/UPHENO_0076319
+http://purl.obolibrary.org/obo/CHEBI_2555	http://purl.obolibrary.org/obo/UPHENO_0076320
+http://purl.obolibrary.org/obo/CHEBI_6432	http://purl.obolibrary.org/obo/UPHENO_0076321
+http://purl.obolibrary.org/obo/CHEBI_4792	http://purl.obolibrary.org/obo/UPHENO_0076322
+http://purl.obolibrary.org/obo/CHEBI_39214	http://purl.obolibrary.org/obo/UPHENO_0076323
+http://purl.obolibrary.org/obo/CHEBI_6015	http://purl.obolibrary.org/obo/UPHENO_0076324
+http://purl.obolibrary.org/obo/CHEBI_16136	http://purl.obolibrary.org/obo/UPHENO_0076325
+http://purl.obolibrary.org/obo/CHEBI_25107	http://purl.obolibrary.org/obo/UPHENO_0076326
+http://purl.obolibrary.org/obo/CHEBI_26710	http://purl.obolibrary.org/obo/UPHENO_0076327
+http://purl.obolibrary.org/obo/CHEBI_30512	http://purl.obolibrary.org/obo/UPHENO_0076328
+http://purl.obolibrary.org/obo/CHEBI_30513	http://purl.obolibrary.org/obo/UPHENO_0076329
+http://purl.obolibrary.org/obo/CHEBI_18291	http://purl.obolibrary.org/obo/UPHENO_0076330
+http://purl.obolibrary.org/obo/CHEBI_22633	http://purl.obolibrary.org/obo/UPHENO_0076331
+http://purl.obolibrary.org/obo/CHEBI_24431	http://purl.obolibrary.org/obo/UPHENO_0076332
+http://purl.obolibrary.org/obo/CHEBI_47499	http://purl.obolibrary.org/obo/UPHENO_0076333
+http://purl.obolibrary.org/obo/CHEBI_27363	http://purl.obolibrary.org/obo/UPHENO_0076334
+http://purl.obolibrary.org/obo/CHEBI_29222	http://purl.obolibrary.org/obo/UPHENO_0076335
+http://purl.obolibrary.org/obo/CHEBI_28694	http://purl.obolibrary.org/obo/UPHENO_0076336
+http://purl.obolibrary.org/obo/CHEBI_28790	http://purl.obolibrary.org/obo/UPHENO_0076337
+http://purl.obolibrary.org/obo/CHEBI_44423	http://purl.obolibrary.org/obo/UPHENO_0076338
+http://purl.obolibrary.org/obo/CHEBI_50826	http://purl.obolibrary.org/obo/UPHENO_0076339
+http://purl.obolibrary.org/obo/CHEBI_27563	http://purl.obolibrary.org/obo/UPHENO_0076340
+http://purl.obolibrary.org/obo/CHEBI_3638	http://purl.obolibrary.org/obo/UPHENO_0076341
+http://purl.obolibrary.org/obo/CHEBI_5615	http://purl.obolibrary.org/obo/UPHENO_0076342
+http://purl.obolibrary.org/obo/CHEBI_35702	http://purl.obolibrary.org/obo/UPHENO_0076343
+http://purl.obolibrary.org/obo/CHEBI_18723	http://purl.obolibrary.org/obo/UPHENO_0076344
+http://purl.obolibrary.org/obo/CHEBI_28260	http://purl.obolibrary.org/obo/UPHENO_0076345
+http://purl.obolibrary.org/obo/CHEBI_5118	http://purl.obolibrary.org/obo/UPHENO_0076346
+http://purl.obolibrary.org/obo/CHEBI_4781	http://purl.obolibrary.org/obo/UPHENO_0076347
+http://purl.obolibrary.org/obo/CHEBI_30297	http://purl.obolibrary.org/obo/UPHENO_0076348
+http://purl.obolibrary.org/obo/CHEBI_22977	http://purl.obolibrary.org/obo/UPHENO_0076349
+http://purl.obolibrary.org/obo/CHEBI_33083	http://purl.obolibrary.org/obo/UPHENO_0076350
+http://purl.obolibrary.org/obo/CHEBI_18248	http://purl.obolibrary.org/obo/UPHENO_0076351
+http://purl.obolibrary.org/obo/CHEBI_7035	http://purl.obolibrary.org/obo/UPHENO_0076352
diff --git a/src/curation/upheno-fillers/wbphenotype/abnormallyDecreasedResistanceOfWholeOrganismToEntity.tsv b/src/curation/upheno-fillers/wbphenotype/abnormallyDecreasedResistanceOfWholeOrganismToEntity.tsv
new file mode 100644
index 00000000..13657e37
--- /dev/null
+++ b/src/curation/upheno-fillers/wbphenotype/abnormallyDecreasedResistanceOfWholeOrganismToEntity.tsv
@@ -0,0 +1,55 @@
+entity	defined_class
+http://purl.obolibrary.org/obo/CHEBI_4781	http://purl.obolibrary.org/obo/UPHENO_0076040
+http://purl.obolibrary.org/obo/CHEBI_22977	http://purl.obolibrary.org/obo/UPHENO_0076041
+http://purl.obolibrary.org/obo/CHEBI_18248	http://purl.obolibrary.org/obo/UPHENO_0076042
+http://purl.obolibrary.org/obo/CHEBI_18723	http://purl.obolibrary.org/obo/UPHENO_0076043
+http://purl.obolibrary.org/obo/CHEBI_5118	http://purl.obolibrary.org/obo/UPHENO_0076044
+http://purl.obolibrary.org/obo/CHEBI_27780	http://purl.obolibrary.org/obo/UPHENO_0076045
+http://purl.obolibrary.org/obo/CHEBI_28790	http://purl.obolibrary.org/obo/UPHENO_0076046
+http://purl.obolibrary.org/obo/CHEBI_44423	http://purl.obolibrary.org/obo/UPHENO_0076047
+http://purl.obolibrary.org/obo/CHEBI_50826	http://purl.obolibrary.org/obo/UPHENO_0076048
+http://purl.obolibrary.org/obo/CHEBI_50949	http://purl.obolibrary.org/obo/UPHENO_0076049
+http://purl.obolibrary.org/obo/CHEBI_30512	http://purl.obolibrary.org/obo/UPHENO_0076050
+http://purl.obolibrary.org/obo/CHEBI_30513	http://purl.obolibrary.org/obo/UPHENO_0076051
+http://purl.obolibrary.org/obo/CHEBI_18291	http://purl.obolibrary.org/obo/UPHENO_0076052
+http://purl.obolibrary.org/obo/CHEBI_24431	http://purl.obolibrary.org/obo/UPHENO_0076053
+http://purl.obolibrary.org/obo/CHEBI_47499	http://purl.obolibrary.org/obo/UPHENO_0076054
+http://purl.obolibrary.org/obo/CHEBI_6432	http://purl.obolibrary.org/obo/UPHENO_0076055
+http://purl.obolibrary.org/obo/CHEBI_38462	http://purl.obolibrary.org/obo/UPHENO_0076056
+http://purl.obolibrary.org/obo/CHEBI_37415	http://purl.obolibrary.org/obo/UPHENO_0076057
+http://purl.obolibrary.org/obo/CHEBI_16236	http://purl.obolibrary.org/obo/UPHENO_0076058
+http://purl.obolibrary.org/obo/CHEBI_38867	http://purl.obolibrary.org/obo/UPHENO_0076059
+http://purl.obolibrary.org/obo/CHEBI_33216	http://purl.obolibrary.org/obo/UPHENO_0076060
+http://purl.obolibrary.org/obo/CHEBI_2555	http://purl.obolibrary.org/obo/UPHENO_0076061
+http://purl.obolibrary.org/obo/CHEBI_63510	http://purl.obolibrary.org/obo/UPHENO_0076062
+http://purl.obolibrary.org/obo/CHEBI_34905	http://purl.obolibrary.org/obo/UPHENO_0076063
+http://purl.obolibrary.org/obo/CHEBI_25195	http://purl.obolibrary.org/obo/UPHENO_0076064
+http://purl.obolibrary.org/obo/CHEBI_25435	http://purl.obolibrary.org/obo/UPHENO_0076065
+http://purl.obolibrary.org/obo/CHEBI_30297	http://purl.obolibrary.org/obo/UPHENO_0076066
+http://purl.obolibrary.org/obo/CHEBI_33083	http://purl.obolibrary.org/obo/UPHENO_0076067
+http://purl.obolibrary.org/obo/CHEBI_7035	http://purl.obolibrary.org/obo/UPHENO_0076068
+http://purl.obolibrary.org/obo/BFO_0000001	http://purl.obolibrary.org/obo/UPHENO_0081418
+http://purl.obolibrary.org/obo/CHEBI_35702	http://purl.obolibrary.org/obo/UPHENO_0076069
+http://purl.obolibrary.org/obo/CHEBI_5615	http://purl.obolibrary.org/obo/UPHENO_0076070
+http://purl.obolibrary.org/obo/CHEBI_28260	http://purl.obolibrary.org/obo/UPHENO_0076071
+http://purl.obolibrary.org/obo/CHEBI_29222	http://purl.obolibrary.org/obo/UPHENO_0076072
+http://purl.obolibrary.org/obo/CHEBI_28694	http://purl.obolibrary.org/obo/UPHENO_0076073
+http://purl.obolibrary.org/obo/CHEBI_27363	http://purl.obolibrary.org/obo/UPHENO_0076074
+http://purl.obolibrary.org/obo/CHEBI_27563	http://purl.obolibrary.org/obo/UPHENO_0076075
+http://purl.obolibrary.org/obo/CHEBI_3638	http://purl.obolibrary.org/obo/UPHENO_0076076
+http://purl.obolibrary.org/obo/CHEBI_25107	http://purl.obolibrary.org/obo/UPHENO_0076077
+http://purl.obolibrary.org/obo/CHEBI_26710	http://purl.obolibrary.org/obo/UPHENO_0076078
+http://purl.obolibrary.org/obo/CHEBI_22633	http://purl.obolibrary.org/obo/UPHENO_0076079
+http://purl.obolibrary.org/obo/CHEBI_23888	http://purl.obolibrary.org/obo/UPHENO_0076080
+http://purl.obolibrary.org/obo/CHEBI_4792	http://purl.obolibrary.org/obo/UPHENO_0076081
+http://purl.obolibrary.org/obo/CHEBI_39214	http://purl.obolibrary.org/obo/UPHENO_0076082
+http://purl.obolibrary.org/obo/CHEBI_6015	http://purl.obolibrary.org/obo/UPHENO_0076083
+http://purl.obolibrary.org/obo/CHEBI_16136	http://purl.obolibrary.org/obo/UPHENO_0076084
+http://purl.obolibrary.org/obo/CHEBI_38324	http://purl.obolibrary.org/obo/UPHENO_0076085
+http://purl.obolibrary.org/obo/CHEBI_25255	http://purl.obolibrary.org/obo/UPHENO_0076086
+http://purl.obolibrary.org/obo/CHEBI_29699	http://purl.obolibrary.org/obo/UPHENO_0076088
+http://purl.obolibrary.org/obo/CHEBI_2814	http://purl.obolibrary.org/obo/UPHENO_0076089
+http://purl.obolibrary.org/obo/CHEBI_38808	http://purl.obolibrary.org/obo/UPHENO_0076090
+http://purl.obolibrary.org/obo/CHEBI_23359	http://purl.obolibrary.org/obo/UPHENO_0076091
+http://purl.obolibrary.org/obo/CHEBI_27638	http://purl.obolibrary.org/obo/UPHENO_0076092
+http://purl.obolibrary.org/obo/CHEBI_25016	http://purl.obolibrary.org/obo/UPHENO_0076093
diff --git a/src/curation/upheno-fillers/wbphenotype/abnormallyDecreasedSizeOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/wbphenotype/abnormallyDecreasedSizeOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..2f39096b
--- /dev/null
+++ b/src/curation/upheno-fillers/wbphenotype/abnormallyDecreasedSizeOfAnatomicalEntity.tsv
@@ -0,0 +1,3 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0068971
+http://purl.obolibrary.org/obo/GO_0005634	http://purl.obolibrary.org/obo/UPHENO_0080058
diff --git a/src/curation/upheno-fillers/wbphenotype/abnormallyDecreasedSizeOfCellularComponent.tsv b/src/curation/upheno-fillers/wbphenotype/abnormallyDecreasedSizeOfCellularComponent.tsv
new file mode 100644
index 00000000..feb77b2a
--- /dev/null
+++ b/src/curation/upheno-fillers/wbphenotype/abnormallyDecreasedSizeOfCellularComponent.tsv
@@ -0,0 +1,3 @@
+entity	defined_class
+http://purl.obolibrary.org/obo/GO_0005575	http://purl.obolibrary.org/obo/UPHENO_0082013
+http://purl.obolibrary.org/obo/GO_0005634	http://purl.obolibrary.org/obo/UPHENO_0082014
diff --git a/src/curation/upheno-fillers/wbphenotype/abnormallyDelayedBiologicalProcess.tsv b/src/curation/upheno-fillers/wbphenotype/abnormallyDelayedBiologicalProcess.tsv
new file mode 100644
index 00000000..79e0e0fe
--- /dev/null
+++ b/src/curation/upheno-fillers/wbphenotype/abnormallyDelayedBiologicalProcess.tsv
@@ -0,0 +1,7 @@
+biological_process	defined_class
+http://purl.obolibrary.org/obo/GO_0032502	http://purl.obolibrary.org/obo/UPHENO_0000508
+http://purl.obolibrary.org/obo/GO_0035188	http://purl.obolibrary.org/obo/UPHENO_0000564
+http://purl.obolibrary.org/obo/GO_0007283	http://purl.obolibrary.org/obo/UPHENO_0000565
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UPHENO_0000543
+http://purl.obolibrary.org/obo/GO_0007049	http://purl.obolibrary.org/obo/UPHENO_0000827
+http://purl.obolibrary.org/obo/GO_0002164	http://purl.obolibrary.org/obo/UPHENO_0000563
diff --git a/src/curation/upheno-fillers/wbphenotype/abnormallyIncreasedLengthOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/wbphenotype/abnormallyIncreasedLengthOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..b9cad5a7
--- /dev/null
+++ b/src/curation/upheno-fillers/wbphenotype/abnormallyIncreasedLengthOfAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0072195
diff --git a/src/curation/upheno-fillers/wbphenotype/abnormallyIncreasedLevelOfChemicalEntity.tsv b/src/curation/upheno-fillers/wbphenotype/abnormallyIncreasedLevelOfChemicalEntity.tsv
new file mode 100644
index 00000000..20dd9e7c
--- /dev/null
+++ b/src/curation/upheno-fillers/wbphenotype/abnormallyIncreasedLevelOfChemicalEntity.tsv
@@ -0,0 +1,9 @@
+chemical_entity	defined_class
+http://purl.obolibrary.org/obo/CHEBI_30413	http://purl.obolibrary.org/obo/UPHENO_0075667
+http://purl.obolibrary.org/obo/CHEBI_26523	http://purl.obolibrary.org/obo/UPHENO_0075668
+http://purl.obolibrary.org/obo/CHEBI_33699	http://purl.obolibrary.org/obo/UPHENO_0048762
+http://purl.obolibrary.org/obo/CHEBI_15422	http://purl.obolibrary.org/obo/UPHENO_0075669
+http://purl.obolibrary.org/obo/CHEBI_24431	http://purl.obolibrary.org/obo/UPHENO_0048707
+http://purl.obolibrary.org/obo/CHEBI_27363	http://purl.obolibrary.org/obo/UPHENO_0075670
+http://purl.obolibrary.org/obo/CHEBI_16240	http://purl.obolibrary.org/obo/UPHENO_0075671
+http://purl.obolibrary.org/obo/CHEBI_18059	http://purl.obolibrary.org/obo/UPHENO_0048763
diff --git a/src/curation/upheno-fillers/wbphenotype/abnormallyIncreasedLevelOfChemicalEntityInLocation.tsv b/src/curation/upheno-fillers/wbphenotype/abnormallyIncreasedLevelOfChemicalEntityInLocation.tsv
new file mode 100644
index 00000000..b8eb5dd2
--- /dev/null
+++ b/src/curation/upheno-fillers/wbphenotype/abnormallyIncreasedLevelOfChemicalEntityInLocation.tsv
@@ -0,0 +1,3 @@
+chemical_entity	location	defined_class
+http://purl.obolibrary.org/obo/CHEBI_24431	http://purl.obolibrary.org/obo/GO_0005829	http://purl.obolibrary.org/obo/UPHENO_0083218
+http://purl.obolibrary.org/obo/CHEBI_29108	http://purl.obolibrary.org/obo/GO_0005829	http://purl.obolibrary.org/obo/UPHENO_0083219
diff --git a/src/curation/upheno-fillers/wbphenotype/abnormallyIncreasedNumberOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/wbphenotype/abnormallyIncreasedNumberOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..c6cfd6eb
--- /dev/null
+++ b/src/curation/upheno-fillers/wbphenotype/abnormallyIncreasedNumberOfAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0014240
diff --git a/src/curation/upheno-fillers/wbphenotype/abnormallyIncreasedOccurrenceOfBiologicalProcess.tsv b/src/curation/upheno-fillers/wbphenotype/abnormallyIncreasedOccurrenceOfBiologicalProcess.tsv
new file mode 100644
index 00000000..392eb5eb
--- /dev/null
+++ b/src/curation/upheno-fillers/wbphenotype/abnormallyIncreasedOccurrenceOfBiologicalProcess.tsv
@@ -0,0 +1,8 @@
+biological_process	defined_class
+http://purl.obolibrary.org/obo/GO_0008219	http://purl.obolibrary.org/obo/UPHENO_0079408
+http://purl.obolibrary.org/obo/GO_0051964	http://purl.obolibrary.org/obo/UPHENO_0081684
+http://purl.obolibrary.org/obo/GO_0008283	http://purl.obolibrary.org/obo/UPHENO_0079263
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UPHENO_0079251
+http://purl.obolibrary.org/obo/GO_0006915	http://purl.obolibrary.org/obo/UPHENO_0079471
+http://purl.obolibrary.org/obo/GO_0008610	http://purl.obolibrary.org/obo/UPHENO_0079292
+http://purl.obolibrary.org/obo/GO_0035825	http://purl.obolibrary.org/obo/UPHENO_0081685
diff --git a/src/curation/upheno-fillers/wbphenotype/abnormallyIncreasedRateOfBiologicalProcess.tsv b/src/curation/upheno-fillers/wbphenotype/abnormallyIncreasedRateOfBiologicalProcess.tsv
new file mode 100644
index 00000000..01abde75
--- /dev/null
+++ b/src/curation/upheno-fillers/wbphenotype/abnormallyIncreasedRateOfBiologicalProcess.tsv
@@ -0,0 +1,8 @@
+biological_process	defined_class
+http://purl.obolibrary.org/obo/GO_0060756	http://purl.obolibrary.org/obo/UPHENO_0055149
+http://purl.obolibrary.org/obo/GO_0043050	http://purl.obolibrary.org/obo/UPHENO_0055146
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UPHENO_0054970
+http://purl.obolibrary.org/obo/GO_0042073	http://purl.obolibrary.org/obo/UPHENO_0055103
+http://purl.obolibrary.org/obo/GO_0018991	http://purl.obolibrary.org/obo/UPHENO_0055108
+http://purl.obolibrary.org/obo/GO_0040011	http://purl.obolibrary.org/obo/UPHENO_0054937
+http://purl.obolibrary.org/obo/GO_0030421	http://purl.obolibrary.org/obo/UPHENO_0055037
diff --git a/src/curation/upheno-fillers/wbphenotype/abnormallyIncreasedRateOfMolecularFunction.tsv b/src/curation/upheno-fillers/wbphenotype/abnormallyIncreasedRateOfMolecularFunction.tsv
new file mode 100644
index 00000000..2447d020
--- /dev/null
+++ b/src/curation/upheno-fillers/wbphenotype/abnormallyIncreasedRateOfMolecularFunction.tsv
@@ -0,0 +1,3 @@
+molecular_function	defined_class
+http://purl.obolibrary.org/obo/GO_0003824	http://purl.obolibrary.org/obo/UPHENO_0048683
+http://purl.obolibrary.org/obo/GO_0003674	http://purl.obolibrary.org/obo/UPHENO_0048661
diff --git a/src/curation/upheno-fillers/wbphenotype/abnormallyIncreasedResistanceOfWholeOrganismToChemicalEntity.tsv b/src/curation/upheno-fillers/wbphenotype/abnormallyIncreasedResistanceOfWholeOrganismToChemicalEntity.tsv
new file mode 100644
index 00000000..29dd0228
--- /dev/null
+++ b/src/curation/upheno-fillers/wbphenotype/abnormallyIncreasedResistanceOfWholeOrganismToChemicalEntity.tsv
@@ -0,0 +1,39 @@
+chemical_entity	defined_class
+http://purl.obolibrary.org/obo/CHEBI_472805	http://purl.obolibrary.org/obo/UPHENO_0076971
+http://purl.obolibrary.org/obo/CHEBI_27732	http://purl.obolibrary.org/obo/UPHENO_0076972
+http://purl.obolibrary.org/obo/CHEBI_23359	http://purl.obolibrary.org/obo/UPHENO_0076973
+http://purl.obolibrary.org/obo/CHEBI_8081	http://purl.obolibrary.org/obo/UPHENO_0076974
+http://purl.obolibrary.org/obo/CHEBI_17051	http://purl.obolibrary.org/obo/UPHENO_0076975
+http://purl.obolibrary.org/obo/CHEBI_64203	http://purl.obolibrary.org/obo/UPHENO_0076976
+http://purl.obolibrary.org/obo/CHEBI_34905	http://purl.obolibrary.org/obo/UPHENO_0076977
+http://purl.obolibrary.org/obo/CHEBI_29699	http://purl.obolibrary.org/obo/UPHENO_0076978
+http://purl.obolibrary.org/obo/CHEBI_2814	http://purl.obolibrary.org/obo/UPHENO_0076979
+http://purl.obolibrary.org/obo/CHEBI_6835	http://purl.obolibrary.org/obo/UPHENO_0076980
+http://purl.obolibrary.org/obo/CHEBI_9727	http://purl.obolibrary.org/obo/UPHENO_0076981
+http://purl.obolibrary.org/obo/CHEBI_37415	http://purl.obolibrary.org/obo/UPHENO_0076982
+http://purl.obolibrary.org/obo/CHEBI_16236	http://purl.obolibrary.org/obo/UPHENO_0076983
+http://purl.obolibrary.org/obo/CHEBI_2555	http://purl.obolibrary.org/obo/UPHENO_0076984
+http://purl.obolibrary.org/obo/CHEBI_37532	http://purl.obolibrary.org/obo/UPHENO_0076985
+http://purl.obolibrary.org/obo/CHEBI_6432	http://purl.obolibrary.org/obo/UPHENO_0076986
+http://purl.obolibrary.org/obo/CHEBI_39214	http://purl.obolibrary.org/obo/UPHENO_0076987
+http://purl.obolibrary.org/obo/CHEBI_6015	http://purl.obolibrary.org/obo/UPHENO_0076988
+http://purl.obolibrary.org/obo/CHEBI_6078	http://purl.obolibrary.org/obo/UPHENO_0076989
+http://purl.obolibrary.org/obo/CHEBI_4290	http://purl.obolibrary.org/obo/UPHENO_0076990
+http://purl.obolibrary.org/obo/CHEBI_18291	http://purl.obolibrary.org/obo/UPHENO_0076991
+http://purl.obolibrary.org/obo/CHEBI_51137	http://purl.obolibrary.org/obo/UPHENO_0076992
+http://purl.obolibrary.org/obo/CHEBI_24431	http://purl.obolibrary.org/obo/UPHENO_0076993
+http://purl.obolibrary.org/obo/CHEBI_46345	http://purl.obolibrary.org/obo/UPHENO_0076994
+http://purl.obolibrary.org/obo/CHEBI_47499	http://purl.obolibrary.org/obo/UPHENO_0076995
+http://purl.obolibrary.org/obo/CHEBI_27363	http://purl.obolibrary.org/obo/UPHENO_0076996
+http://purl.obolibrary.org/obo/CHEBI_28694	http://purl.obolibrary.org/obo/UPHENO_0076997
+http://purl.obolibrary.org/obo/CHEBI_28790	http://purl.obolibrary.org/obo/UPHENO_0076998
+http://purl.obolibrary.org/obo/CHEBI_3638	http://purl.obolibrary.org/obo/UPHENO_0076999
+http://purl.obolibrary.org/obo/CHEBI_28112	http://purl.obolibrary.org/obo/UPHENO_0077000
+http://purl.obolibrary.org/obo/CHEBI_5615	http://purl.obolibrary.org/obo/UPHENO_0077001
+http://purl.obolibrary.org/obo/CHEBI_18723	http://purl.obolibrary.org/obo/UPHENO_0077002
+http://purl.obolibrary.org/obo/CHEBI_4887	http://purl.obolibrary.org/obo/UPHENO_0077003
+http://purl.obolibrary.org/obo/CHEBI_5118	http://purl.obolibrary.org/obo/UPHENO_0077004
+http://purl.obolibrary.org/obo/CHEBI_4046	http://purl.obolibrary.org/obo/UPHENO_0077005
+http://purl.obolibrary.org/obo/CHEBI_18243	http://purl.obolibrary.org/obo/UPHENO_0077006
+http://purl.obolibrary.org/obo/CHEBI_22977	http://purl.obolibrary.org/obo/UPHENO_0077007
+http://purl.obolibrary.org/obo/CHEBI_7035	http://purl.obolibrary.org/obo/UPHENO_0077008
diff --git a/src/curation/upheno-fillers/wbphenotype/abnormallyIncreasedResistanceOfWholeOrganismToEntity.tsv b/src/curation/upheno-fillers/wbphenotype/abnormallyIncreasedResistanceOfWholeOrganismToEntity.tsv
new file mode 100644
index 00000000..659b74e5
--- /dev/null
+++ b/src/curation/upheno-fillers/wbphenotype/abnormallyIncreasedResistanceOfWholeOrganismToEntity.tsv
@@ -0,0 +1,48 @@
+entity	defined_class
+http://purl.obolibrary.org/obo/CHEBI_4046	http://purl.obolibrary.org/obo/UPHENO_0078744
+http://purl.obolibrary.org/obo/CHEBI_18243	http://purl.obolibrary.org/obo/UPHENO_0078745
+http://purl.obolibrary.org/obo/CHEBI_22977	http://purl.obolibrary.org/obo/UPHENO_0078746
+http://purl.obolibrary.org/obo/CHEBI_7035	http://purl.obolibrary.org/obo/UPHENO_0078747
+http://purl.obolibrary.org/obo/BFO_0000001	http://purl.obolibrary.org/obo/UPHENO_0082030
+http://purl.obolibrary.org/obo/CHEBI_18723	http://purl.obolibrary.org/obo/UPHENO_0078748
+http://purl.obolibrary.org/obo/CHEBI_5615	http://purl.obolibrary.org/obo/UPHENO_0078749
+http://purl.obolibrary.org/obo/CHEBI_35623	http://purl.obolibrary.org/obo/UPHENO_0078750
+http://purl.obolibrary.org/obo/CHEBI_4887	http://purl.obolibrary.org/obo/UPHENO_0078751
+http://purl.obolibrary.org/obo/CHEBI_5118	http://purl.obolibrary.org/obo/UPHENO_0078752
+http://purl.obolibrary.org/obo/CHEBI_28694	http://purl.obolibrary.org/obo/UPHENO_0078753
+http://purl.obolibrary.org/obo/CHEBI_27363	http://purl.obolibrary.org/obo/UPHENO_0078754
+http://purl.obolibrary.org/obo/CHEBI_28790	http://purl.obolibrary.org/obo/UPHENO_0078755
+http://purl.obolibrary.org/obo/CHEBI_50949	http://purl.obolibrary.org/obo/UPHENO_0078756
+http://purl.obolibrary.org/obo/CHEBI_3638	http://purl.obolibrary.org/obo/UPHENO_0078757
+http://purl.obolibrary.org/obo/CHEBI_28112	http://purl.obolibrary.org/obo/UPHENO_0078758
+http://purl.obolibrary.org/obo/CHEBI_4290	http://purl.obolibrary.org/obo/UPHENO_0078759
+http://purl.obolibrary.org/obo/CHEBI_23888	http://purl.obolibrary.org/obo/UPHENO_0078760
+http://purl.obolibrary.org/obo/CHEBI_18291	http://purl.obolibrary.org/obo/UPHENO_0078761
+http://purl.obolibrary.org/obo/CHEBI_51137	http://purl.obolibrary.org/obo/UPHENO_0078762
+http://purl.obolibrary.org/obo/CHEBI_46345	http://purl.obolibrary.org/obo/UPHENO_0078763
+http://purl.obolibrary.org/obo/CHEBI_24431	http://purl.obolibrary.org/obo/UPHENO_0078764
+http://purl.obolibrary.org/obo/CHEBI_47499	http://purl.obolibrary.org/obo/UPHENO_0078765
+http://purl.obolibrary.org/obo/CHEBI_6432	http://purl.obolibrary.org/obo/UPHENO_0078766
+http://purl.obolibrary.org/obo/CHEBI_39214	http://purl.obolibrary.org/obo/UPHENO_0078767
+http://purl.obolibrary.org/obo/CHEBI_6015	http://purl.obolibrary.org/obo/UPHENO_0078768
+http://purl.obolibrary.org/obo/CHEBI_38462	http://purl.obolibrary.org/obo/UPHENO_0078769
+http://purl.obolibrary.org/obo/CHEBI_6078	http://purl.obolibrary.org/obo/UPHENO_0078770
+http://purl.obolibrary.org/obo/CHEBI_37415	http://purl.obolibrary.org/obo/UPHENO_0078771
+http://purl.obolibrary.org/obo/CHEBI_16236	http://purl.obolibrary.org/obo/UPHENO_0078772
+http://purl.obolibrary.org/obo/CHEBI_38867	http://purl.obolibrary.org/obo/UPHENO_0078773
+http://purl.obolibrary.org/obo/CHEBI_6835	http://purl.obolibrary.org/obo/UPHENO_0078774
+http://purl.obolibrary.org/obo/CHEBI_9727	http://purl.obolibrary.org/obo/UPHENO_0078775
+http://purl.obolibrary.org/obo/CHEBI_2555	http://purl.obolibrary.org/obo/UPHENO_0078776
+http://purl.obolibrary.org/obo/CHEBI_37532	http://purl.obolibrary.org/obo/UPHENO_0078777
+http://purl.obolibrary.org/obo/CHEBI_38324	http://purl.obolibrary.org/obo/UPHENO_0078778
+http://purl.obolibrary.org/obo/CHEBI_64203	http://purl.obolibrary.org/obo/UPHENO_0078779
+http://purl.obolibrary.org/obo/CHEBI_34905	http://purl.obolibrary.org/obo/UPHENO_0078780
+http://purl.obolibrary.org/obo/CHEBI_29699	http://purl.obolibrary.org/obo/UPHENO_0078782
+http://purl.obolibrary.org/obo/CHEBI_2814	http://purl.obolibrary.org/obo/UPHENO_0078783
+http://purl.obolibrary.org/obo/CHEBI_38808	http://purl.obolibrary.org/obo/UPHENO_0078784
+http://purl.obolibrary.org/obo/CHEBI_472805	http://purl.obolibrary.org/obo/UPHENO_0078785
+http://purl.obolibrary.org/obo/CHEBI_23359	http://purl.obolibrary.org/obo/UPHENO_0078786
+http://purl.obolibrary.org/obo/CHEBI_27732	http://purl.obolibrary.org/obo/UPHENO_0078787
+http://purl.obolibrary.org/obo/CHEBI_8081	http://purl.obolibrary.org/obo/UPHENO_0078788
+http://purl.obolibrary.org/obo/CHEBI_17051	http://purl.obolibrary.org/obo/UPHENO_0078789
+http://purl.obolibrary.org/obo/CHEBI_25435	http://purl.obolibrary.org/obo/UPHENO_0078790
diff --git a/src/curation/upheno-fillers/wbphenotype/abnormallyIncreasedSizeOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/wbphenotype/abnormallyIncreasedSizeOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..e3b88008
--- /dev/null
+++ b/src/curation/upheno-fillers/wbphenotype/abnormallyIncreasedSizeOfAnatomicalEntity.tsv
@@ -0,0 +1,3 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0001072
+http://purl.obolibrary.org/obo/GO_0005634	http://purl.obolibrary.org/obo/UPHENO_0076935
diff --git a/src/curation/upheno-fillers/wbphenotype/abnormallyIncreasedSizeOfCellularComponent.tsv b/src/curation/upheno-fillers/wbphenotype/abnormallyIncreasedSizeOfCellularComponent.tsv
new file mode 100644
index 00000000..f679bd8f
--- /dev/null
+++ b/src/curation/upheno-fillers/wbphenotype/abnormallyIncreasedSizeOfCellularComponent.tsv
@@ -0,0 +1,3 @@
+entity	defined_class
+http://purl.obolibrary.org/obo/GO_0005575	http://purl.obolibrary.org/obo/UPHENO_0080309
+http://purl.obolibrary.org/obo/GO_0005634	http://purl.obolibrary.org/obo/UPHENO_0080311
diff --git a/src/curation/upheno-fillers/wbphenotype/abnormallyRotatedAnatomicalEntity.tsv b/src/curation/upheno-fillers/wbphenotype/abnormallyRotatedAnatomicalEntity.tsv
new file mode 100644
index 00000000..c6c3940c
--- /dev/null
+++ b/src/curation/upheno-fillers/wbphenotype/abnormallyRotatedAnatomicalEntity.tsv
@@ -0,0 +1,3 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0082022
+http://purl.obolibrary.org/obo/GO_0005634	http://purl.obolibrary.org/obo/UPHENO_0082029
diff --git a/src/curation/upheno-fillers/wbphenotype/atreticAnatomicalEntity.tsv b/src/curation/upheno-fillers/wbphenotype/atreticAnatomicalEntity.tsv
new file mode 100644
index 00000000..61fa7b4a
--- /dev/null
+++ b/src/curation/upheno-fillers/wbphenotype/atreticAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0063565
diff --git a/src/curation/upheno-fillers/wbphenotype/blisteredAnatomicalEntity.tsv b/src/curation/upheno-fillers/wbphenotype/blisteredAnatomicalEntity.tsv
new file mode 100644
index 00000000..7e346631
--- /dev/null
+++ b/src/curation/upheno-fillers/wbphenotype/blisteredAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0011967
diff --git a/src/curation/upheno-fillers/wbphenotype/mislocalisedAnatomicalEntity.tsv b/src/curation/upheno-fillers/wbphenotype/mislocalisedAnatomicalEntity.tsv
new file mode 100644
index 00000000..3cd97ed3
--- /dev/null
+++ b/src/curation/upheno-fillers/wbphenotype/mislocalisedAnatomicalEntity.tsv
@@ -0,0 +1,5 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0053580
+http://purl.obolibrary.org/obo/GO_0030424	http://purl.obolibrary.org/obo/UPHENO_0077192
+http://purl.obolibrary.org/obo/GO_0043005	http://purl.obolibrary.org/obo/UPHENO_0077193
+http://purl.obolibrary.org/obo/GO_0032154	http://purl.obolibrary.org/obo/UPHENO_0077194
diff --git a/src/curation/upheno-fillers/xpo/abnormalAbsenceOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/xpo/abnormalAbsenceOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..8185662f
--- /dev/null
+++ b/src/curation/upheno-fillers/xpo/abnormalAbsenceOfAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0008523
diff --git a/src/curation/upheno-fillers/xpo/abnormalAbsenceOfAnatomicalEntityInLocation.tsv b/src/curation/upheno-fillers/xpo/abnormalAbsenceOfAnatomicalEntityInLocation.tsv
new file mode 100644
index 00000000..b7121acc
--- /dev/null
+++ b/src/curation/upheno-fillers/xpo/abnormalAbsenceOfAnatomicalEntityInLocation.tsv
@@ -0,0 +1 @@
+anatomical_entity	location	defined_class
diff --git a/src/curation/upheno-fillers/xpo/abnormalAbsenceOfBiologicalProcess.tsv b/src/curation/upheno-fillers/xpo/abnormalAbsenceOfBiologicalProcess.tsv
new file mode 100644
index 00000000..06c91cf1
--- /dev/null
+++ b/src/curation/upheno-fillers/xpo/abnormalAbsenceOfBiologicalProcess.tsv
@@ -0,0 +1,18 @@
+biological_process	defined_class
+http://purl.obolibrary.org/obo/GO_0007634	http://purl.obolibrary.org/obo/UPHENO_0078490
+http://purl.obolibrary.org/obo/GO_0007617	http://purl.obolibrary.org/obo/UPHENO_0078491
+http://purl.obolibrary.org/obo/GO_0048266	http://purl.obolibrary.org/obo/UPHENO_0078492
+http://purl.obolibrary.org/obo/GO_0007626	http://purl.obolibrary.org/obo/UPHENO_0078493
+http://purl.obolibrary.org/obo/GO_0007638	http://purl.obolibrary.org/obo/UPHENO_0078494
+http://purl.obolibrary.org/obo/GO_0008286	http://purl.obolibrary.org/obo/UPHENO_0078495
+http://purl.obolibrary.org/obo/GO_0007631	http://purl.obolibrary.org/obo/UPHENO_0034090
+http://purl.obolibrary.org/obo/GO_0007610	http://purl.obolibrary.org/obo/UPHENO_0034056
+http://purl.obolibrary.org/obo/GO_0007632	http://purl.obolibrary.org/obo/UPHENO_0078496
+http://purl.obolibrary.org/obo/GO_0007552	http://purl.obolibrary.org/obo/UPHENO_0080958
+http://purl.obolibrary.org/obo/GO_0042048	http://purl.obolibrary.org/obo/UPHENO_0078497
+http://purl.obolibrary.org/obo/GO_0071625	http://purl.obolibrary.org/obo/UPHENO_0078498
+http://purl.obolibrary.org/obo/GO_0036269	http://purl.obolibrary.org/obo/UPHENO_0078499
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UPHENO_0034024
+http://purl.obolibrary.org/obo/GO_0007619	http://purl.obolibrary.org/obo/UPHENO_0078500
+http://purl.obolibrary.org/obo/GO_0035187	http://purl.obolibrary.org/obo/UPHENO_0078501
+http://purl.obolibrary.org/obo/GO_0035176	http://purl.obolibrary.org/obo/UPHENO_0078502
diff --git a/src/curation/upheno-fillers/xpo/abnormalAbsenceOfBiologicalProcessInLocation.tsv b/src/curation/upheno-fillers/xpo/abnormalAbsenceOfBiologicalProcessInLocation.tsv
new file mode 100644
index 00000000..1ff90430
--- /dev/null
+++ b/src/curation/upheno-fillers/xpo/abnormalAbsenceOfBiologicalProcessInLocation.tsv
@@ -0,0 +1 @@
+biological_process	location	defined_class
diff --git a/src/curation/upheno-fillers/xpo/abnormalAgenesisOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/xpo/abnormalAgenesisOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..86daa471
--- /dev/null
+++ b/src/curation/upheno-fillers/xpo/abnormalAgenesisOfAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0080325
diff --git a/src/curation/upheno-fillers/xpo/abnormalAnatomicalEntity.tsv b/src/curation/upheno-fillers/xpo/abnormalAnatomicalEntity.tsv
new file mode 100644
index 00000000..ebe14380
--- /dev/null
+++ b/src/curation/upheno-fillers/xpo/abnormalAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0002536
diff --git a/src/curation/upheno-fillers/xpo/abnormalBiologicalProcess.tsv b/src/curation/upheno-fillers/xpo/abnormalBiologicalProcess.tsv
new file mode 100644
index 00000000..f541c10d
--- /dev/null
+++ b/src/curation/upheno-fillers/xpo/abnormalBiologicalProcess.tsv
@@ -0,0 +1,213 @@
+biological_process	defined_class
+http://purl.obolibrary.org/obo/GO_0006536	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0046110	http://purl.obolibrary.org/obo/UPHENO_0078582
+http://purl.obolibrary.org/obo/GO_0007626	http://purl.obolibrary.org/obo/UPHENO_0050571
+http://purl.obolibrary.org/obo/GO_0030509	http://purl.obolibrary.org/obo/UPHENO_0050213
+http://purl.obolibrary.org/obo/GO_0003383	http://purl.obolibrary.org/obo/UPHENO_0078656
+http://purl.obolibrary.org/obo/GO_0003384	http://purl.obolibrary.org/obo/UPHENO_0078657
+http://purl.obolibrary.org/obo/GO_0019725	http://purl.obolibrary.org/obo/UPHENO_0049601
+http://purl.obolibrary.org/obo/GO_0061611	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0043647	http://purl.obolibrary.org/obo/UPHENO_0083100
+http://purl.obolibrary.org/obo/GO_0043648	http://purl.obolibrary.org/obo/UPHENO_0078584
+http://purl.obolibrary.org/obo/GO_0006525	http://purl.obolibrary.org/obo/UPHENO_0078588
+http://purl.obolibrary.org/obo/GO_0003015	http://purl.obolibrary.org/obo/UPHENO_0051192
+http://purl.obolibrary.org/obo/GO_0032259	http://purl.obolibrary.org/obo/UPHENO_0049861
+http://purl.obolibrary.org/obo/GO_0006522	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0009119	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0007617	http://purl.obolibrary.org/obo/UPHENO_0049614
+http://purl.obolibrary.org/obo/GO_0006528	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0044281	http://purl.obolibrary.org/obo/UPHENO_0049618
+http://purl.obolibrary.org/obo/GO_0046102	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0046100	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0006884	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0007610	http://purl.obolibrary.org/obo/UPHENO_0049622
+http://purl.obolibrary.org/obo/GO_1900533	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0006089	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0046108	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0035089	http://purl.obolibrary.org/obo/UPHENO_0051199
+http://purl.obolibrary.org/obo/GO_0006094	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0008152	http://purl.obolibrary.org/obo/UPHENO_0049873
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UPHENO_0049587
+http://purl.obolibrary.org/obo/GO_0040009	http://purl.obolibrary.org/obo/UPHENO_0078665
+http://purl.obolibrary.org/obo/GO_0001756	http://purl.obolibrary.org/obo/UPHENO_0051395
+http://purl.obolibrary.org/obo/GO_0007619	http://purl.obolibrary.org/obo/UPHENO_0078667
+http://purl.obolibrary.org/obo/GO_0048878	http://purl.obolibrary.org/obo/UPHENO_0049628
+http://purl.obolibrary.org/obo/GO_0048873	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0048872	http://purl.obolibrary.org/obo/UPHENO_0050916
+http://purl.obolibrary.org/obo/GO_0008617	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0048871	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0006553	http://purl.obolibrary.org/obo/UPHENO_0078602
+http://purl.obolibrary.org/obo/GO_0006551	http://purl.obolibrary.org/obo/UPHENO_0051211
+http://purl.obolibrary.org/obo/GO_0016477	http://purl.obolibrary.org/obo/UPHENO_0049643
+http://purl.obolibrary.org/obo/GO_0019507	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0019748	http://purl.obolibrary.org/obo/UPHENO_0050245
+http://purl.obolibrary.org/obo/GO_0019627	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0009948	http://purl.obolibrary.org/obo/UPHENO_0050184
+http://purl.obolibrary.org/obo/GO_0019860	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0097009	http://purl.obolibrary.org/obo/UPHENO_0083081
+http://purl.obolibrary.org/obo/GO_0009946	http://purl.obolibrary.org/obo/UPHENO_0050192
+http://purl.obolibrary.org/obo/GO_1901605	http://purl.obolibrary.org/obo/UPHENO_0050249
+http://purl.obolibrary.org/obo/GO_0090162	http://purl.obolibrary.org/obo/UPHENO_0050250
+http://purl.obolibrary.org/obo/GO_0006547	http://purl.obolibrary.org/obo/UPHENO_0078607
+http://purl.obolibrary.org/obo/GO_0001894	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0006544	http://purl.obolibrary.org/obo/UPHENO_0078609
+http://purl.obolibrary.org/obo/GO_0007634	http://purl.obolibrary.org/obo/UPHENO_0050588
+http://purl.obolibrary.org/obo/GO_0006549	http://purl.obolibrary.org/obo/UPHENO_0078610
+http://purl.obolibrary.org/obo/GO_0001776	http://purl.obolibrary.org/obo/UPHENO_0051405
+http://purl.obolibrary.org/obo/GO_0007638	http://purl.obolibrary.org/obo/UPHENO_0050592
+http://purl.obolibrary.org/obo/GO_0008286	http://purl.obolibrary.org/obo/UPHENO_0078675
+http://purl.obolibrary.org/obo/GO_0060071	http://purl.obolibrary.org/obo/UPHENO_0051408
+http://purl.obolibrary.org/obo/GO_0007631	http://purl.obolibrary.org/obo/UPHENO_0049664
+http://purl.obolibrary.org/obo/GO_0060070	http://purl.obolibrary.org/obo/UPHENO_0051409
+http://purl.obolibrary.org/obo/GO_1900752	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0007632	http://purl.obolibrary.org/obo/UPHENO_0050596
+http://purl.obolibrary.org/obo/GO_0019857	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0046449	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0042403	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0019859	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0019858	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0001659	http://purl.obolibrary.org/obo/UPHENO_0078619
+http://purl.obolibrary.org/obo/GO_0090163	http://purl.obolibrary.org/obo/UPHENO_0078679
+http://purl.obolibrary.org/obo/GO_0006734	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0006973	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0001843	http://purl.obolibrary.org/obo/UPHENO_0051077
+http://purl.obolibrary.org/obo/GO_0042592	http://purl.obolibrary.org/obo/UPHENO_0049904
+http://purl.obolibrary.org/obo/GO_0046034	http://purl.obolibrary.org/obo/UPHENO_0050261
+http://purl.obolibrary.org/obo/GO_0003341	http://purl.obolibrary.org/obo/UPHENO_0050263
+http://purl.obolibrary.org/obo/GO_0009445	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0046716	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0008361	http://purl.obolibrary.org/obo/UPHENO_0078658
+http://purl.obolibrary.org/obo/GO_0051189	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0050891	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0006739	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0019369	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0009448	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0046384	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0007254	http://purl.obolibrary.org/obo/UPHENO_0078661
+http://purl.obolibrary.org/obo/GO_0006041	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0005990	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0009798	http://purl.obolibrary.org/obo/UPHENO_0050169
+http://purl.obolibrary.org/obo/GO_0006633	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0003127	http://purl.obolibrary.org/obo/UPHENO_0078668
+http://purl.obolibrary.org/obo/GO_1904126	http://purl.obolibrary.org/obo/UPHENO_0078669
+http://purl.obolibrary.org/obo/GO_0048677	http://purl.obolibrary.org/obo/UPHENO_0078670
+http://purl.obolibrary.org/obo/GO_0007284	http://purl.obolibrary.org/obo/UPHENO_0078671
+http://purl.obolibrary.org/obo/GO_0080144	http://purl.obolibrary.org/obo/UPHENO_0050957
+http://purl.obolibrary.org/obo/GO_0007164	http://purl.obolibrary.org/obo/UPHENO_0078672
+http://purl.obolibrary.org/obo/GO_0006631	http://purl.obolibrary.org/obo/UPHENO_0078646
+http://purl.obolibrary.org/obo/GO_0055082	http://purl.obolibrary.org/obo/UPHENO_0049711
+http://purl.obolibrary.org/obo/GO_0036269	http://purl.obolibrary.org/obo/UPHENO_0050289
+http://purl.obolibrary.org/obo/GO_0055088	http://purl.obolibrary.org/obo/UPHENO_0051254
+http://purl.obolibrary.org/obo/GO_0035176	http://purl.obolibrary.org/obo/UPHENO_0049713
+http://purl.obolibrary.org/obo/GO_0006749	http://purl.obolibrary.org/obo/UPHENO_0078709
+http://purl.obolibrary.org/obo/GO_0007155	http://purl.obolibrary.org/obo/UPHENO_0049969
+http://purl.obolibrary.org/obo/GO_0046486	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0042440	http://purl.obolibrary.org/obo/UPHENO_0050766
+http://purl.obolibrary.org/obo/GO_0043651	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0002262	http://purl.obolibrary.org/obo/UPHENO_0050968
+http://purl.obolibrary.org/obo/GO_0042445	http://purl.obolibrary.org/obo/UPHENO_0050767
+http://purl.obolibrary.org/obo/GO_0061523	http://purl.obolibrary.org/obo/UPHENO_0078676
+http://purl.obolibrary.org/obo/GO_0042446	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0042447	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0006071	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0001736	http://purl.obolibrary.org/obo/UPHENO_0078678
+http://purl.obolibrary.org/obo/GO_0006629	http://purl.obolibrary.org/obo/UPHENO_0049723
+http://purl.obolibrary.org/obo/GO_0006935	http://purl.obolibrary.org/obo/UPHENO_0049727
+http://purl.obolibrary.org/obo/GO_0051301	http://purl.obolibrary.org/obo/UPHENO_0049729
+http://purl.obolibrary.org/obo/GO_0043480	http://purl.obolibrary.org/obo/UPHENO_0078654
+http://purl.obolibrary.org/obo/GO_0006014	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0006013	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0042278	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0006012	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0060249	http://purl.obolibrary.org/obo/UPHENO_0050643
+http://purl.obolibrary.org/obo/GO_0009092	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0010992	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0003309	http://purl.obolibrary.org/obo/UPHENO_0050322
+http://purl.obolibrary.org/obo/GO_0006816	http://purl.obolibrary.org/obo/UPHENO_0050323
+http://purl.obolibrary.org/obo/GO_0016055	http://purl.obolibrary.org/obo/UPHENO_0051114
+http://purl.obolibrary.org/obo/GO_0070050	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0006006	http://purl.obolibrary.org/obo/UPHENO_0050472
+http://purl.obolibrary.org/obo/GO_0006127	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0000023	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0072350	http://purl.obolibrary.org/obo/UPHENO_0078590
+http://purl.obolibrary.org/obo/GO_0010509	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0006000	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0060250	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0008543	http://purl.obolibrary.org/obo/UPHENO_0050788
+http://purl.obolibrary.org/obo/GO_0090307	http://purl.obolibrary.org/obo/UPHENO_0051482
+http://purl.obolibrary.org/obo/GO_0090427	http://purl.obolibrary.org/obo/UPHENO_0078663
+http://purl.obolibrary.org/obo/GO_0036333	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0036335	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0036334	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0070178	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0006807	http://purl.obolibrary.org/obo/UPHENO_0049748
+http://purl.obolibrary.org/obo/GO_0033500	http://purl.obolibrary.org/obo/UPHENO_0050791
+http://purl.obolibrary.org/obo/GO_0019674	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0038092	http://purl.obolibrary.org/obo/UPHENO_0050483
+http://purl.obolibrary.org/obo/GO_0007369	http://purl.obolibrary.org/obo/UPHENO_0050028
+http://purl.obolibrary.org/obo/GO_0006835	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0048473	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_1902421	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0000050	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0036109	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0007368	http://purl.obolibrary.org/obo/UPHENO_0050489
+http://purl.obolibrary.org/obo/GO_0060468	http://purl.obolibrary.org/obo/UPHENO_0080605
+http://purl.obolibrary.org/obo/GO_0060586	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0001947	http://purl.obolibrary.org/obo/UPHENO_0050811
+http://purl.obolibrary.org/obo/GO_0006020	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0008203	http://purl.obolibrary.org/obo/UPHENO_0050500
+http://purl.obolibrary.org/obo/GO_0018924	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0030010	http://purl.obolibrary.org/obo/UPHENO_0050822
+http://purl.obolibrary.org/obo/GO_0019693	http://purl.obolibrary.org/obo/UPHENO_0050826
+http://purl.obolibrary.org/obo/GO_0007548	http://purl.obolibrary.org/obo/UPHENO_0051138
+http://purl.obolibrary.org/obo/GO_0032963	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0051225	http://purl.obolibrary.org/obo/UPHENO_0051009
+http://purl.obolibrary.org/obo/GO_0070085	http://purl.obolibrary.org/obo/UPHENO_0078623
+http://purl.obolibrary.org/obo/GO_1903332	http://purl.obolibrary.org/obo/UPHENO_0078655
+http://purl.obolibrary.org/obo/GO_0006570	http://purl.obolibrary.org/obo/UPHENO_0051525
+http://purl.obolibrary.org/obo/GO_0006573	http://purl.obolibrary.org/obo/UPHENO_0078626
+http://purl.obolibrary.org/obo/GO_0060047	http://purl.obolibrary.org/obo/UPHENO_0051311
+http://purl.obolibrary.org/obo/GO_0022007	http://purl.obolibrary.org/obo/UPHENO_0050367
+http://purl.obolibrary.org/obo/GO_0050801	http://purl.obolibrary.org/obo/UPHENO_0050080
+http://purl.obolibrary.org/obo/GO_0006568	http://purl.obolibrary.org/obo/UPHENO_0078632
+http://purl.obolibrary.org/obo/GO_0048846	http://purl.obolibrary.org/obo/UPHENO_0051532
+http://purl.obolibrary.org/obo/GO_0006566	http://purl.obolibrary.org/obo/UPHENO_0078634
+http://purl.obolibrary.org/obo/GO_0001676	http://purl.obolibrary.org/obo/UPHENO_0078635
+http://purl.obolibrary.org/obo/GO_0042060	http://purl.obolibrary.org/obo/UPHENO_0050846
+http://purl.obolibrary.org/obo/GO_0045454	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0006560	http://purl.obolibrary.org/obo/UPHENO_0078636
+http://purl.obolibrary.org/obo/GO_0015839	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0006563	http://purl.obolibrary.org/obo/UPHENO_0078639
+http://purl.obolibrary.org/obo/GO_0009950	http://purl.obolibrary.org/obo/UPHENO_0050167
+http://purl.obolibrary.org/obo/GO_0071625	http://purl.obolibrary.org/obo/UPHENO_0078662
+http://purl.obolibrary.org/obo/GO_0032053	http://purl.obolibrary.org/obo/UPHENO_0078666
+http://purl.obolibrary.org/obo/GO_0016486	http://purl.obolibrary.org/obo/UPHENO_0051168
+http://purl.obolibrary.org/obo/GO_0046094	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0003401	http://purl.obolibrary.org/obo/UPHENO_0051323
+http://purl.obolibrary.org/obo/GO_0032502	http://purl.obolibrary.org/obo/UPHENO_0050108
+http://purl.obolibrary.org/obo/GO_0006599	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0046098	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0009069	http://purl.obolibrary.org/obo/UPHENO_0078643
+http://purl.obolibrary.org/obo/GO_0006591	http://purl.obolibrary.org/obo/UPHENO_0078644
+http://purl.obolibrary.org/obo/GO_0044237	http://purl.obolibrary.org/obo/UPHENO_0050113
+http://purl.obolibrary.org/obo/GO_0060028	http://purl.obolibrary.org/obo/UPHENO_0051330
+http://purl.obolibrary.org/obo/GO_0070988	http://purl.obolibrary.org/obo/UPHENO_0050860
+http://purl.obolibrary.org/obo/GO_0044238	http://purl.obolibrary.org/obo/UPHENO_0050116
+http://purl.obolibrary.org/obo/GO_0060026	http://purl.obolibrary.org/obo/UPHENO_0051336
+http://purl.obolibrary.org/obo/GO_0070986	http://purl.obolibrary.org/obo/UPHENO_0050189
+http://purl.obolibrary.org/obo/GO_0046083	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0006468	http://purl.obolibrary.org/obo/UPHENO_0050125
+http://purl.obolibrary.org/obo/GO_0006105	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0048266	http://purl.obolibrary.org/obo/UPHENO_0078674
+http://purl.obolibrary.org/obo/GO_0043490	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0043491	http://purl.obolibrary.org/obo/UPHENO_0050554
+http://purl.obolibrary.org/obo/GO_0009058	http://purl.obolibrary.org/obo/UPHENO_0049835
+http://purl.obolibrary.org/obo/GO_0033609	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0009056	http://purl.obolibrary.org/obo/UPHENO_0049836
+http://purl.obolibrary.org/obo/GO_0006580	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0061484	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0060271	http://purl.obolibrary.org/obo/UPHENO_0050690
+http://purl.obolibrary.org/obo/GO_0007552	http://purl.obolibrary.org/obo/UPHENO_0080606
+http://purl.obolibrary.org/obo/GO_0042048	http://purl.obolibrary.org/obo/UPHENO_0050130
+http://purl.obolibrary.org/obo/GO_0006590	http://purl.obolibrary.org/obo/UPHENO_0078677
+http://purl.obolibrary.org/obo/GO_0019530	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/xpo/abnormalBiologicalProcessInLocation.tsv b/src/curation/upheno-fillers/xpo/abnormalBiologicalProcessInLocation.tsv
new file mode 100644
index 00000000..1ff90430
--- /dev/null
+++ b/src/curation/upheno-fillers/xpo/abnormalBiologicalProcessInLocation.tsv
@@ -0,0 +1 @@
+biological_process	location	defined_class
diff --git a/src/curation/upheno-fillers/xpo/abnormalCoilingOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/xpo/abnormalCoilingOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..d7fc165c
--- /dev/null
+++ b/src/curation/upheno-fillers/xpo/abnormalCoilingOfAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0078441
diff --git a/src/curation/upheno-fillers/xpo/abnormalDevelopmentOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/xpo/abnormalDevelopmentOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..def60a39
--- /dev/null
+++ b/src/curation/upheno-fillers/xpo/abnormalDevelopmentOfAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0081436
diff --git a/src/curation/upheno-fillers/xpo/abnormalMolecularFunction.tsv b/src/curation/upheno-fillers/xpo/abnormalMolecularFunction.tsv
new file mode 100644
index 00000000..4adc72f4
--- /dev/null
+++ b/src/curation/upheno-fillers/xpo/abnormalMolecularFunction.tsv
@@ -0,0 +1,19 @@
+molecular_function	defined_class
+http://purl.obolibrary.org/obo/GO_0016829	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0004197	http://purl.obolibrary.org/obo/UPHENO_0080025
+http://purl.obolibrary.org/obo/GO_0003674	http://purl.obolibrary.org/obo/UPHENO_0031743
+http://purl.obolibrary.org/obo/GO_0001055	http://purl.obolibrary.org/obo/UPHENO_0080026
+http://purl.obolibrary.org/obo/GO_0052598	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0004711	http://purl.obolibrary.org/obo/UPHENO_0080027
+http://purl.obolibrary.org/obo/GO_0004745	http://purl.obolibrary.org/obo/UPHENO_0080028
+http://purl.obolibrary.org/obo/GO_0004707	http://purl.obolibrary.org/obo/UPHENO_0080024
+http://purl.obolibrary.org/obo/GO_0003824	http://purl.obolibrary.org/obo/UPHENO_0031742
+http://purl.obolibrary.org/obo/GO_0032451	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0035173	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0016491	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0016740	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0009975	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0016787	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0016853	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0016874	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0061783	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/xpo/abnormalMorphologyOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/xpo/abnormalMorphologyOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..89cc10d7
--- /dev/null
+++ b/src/curation/upheno-fillers/xpo/abnormalMorphologyOfAnatomicalEntity.tsv
@@ -0,0 +1,9 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
diff --git a/src/curation/upheno-fillers/xpo/abnormalMorphologyOfAnatomicalEntityInLocation.tsv b/src/curation/upheno-fillers/xpo/abnormalMorphologyOfAnatomicalEntityInLocation.tsv
new file mode 100644
index 00000000..b7121acc
--- /dev/null
+++ b/src/curation/upheno-fillers/xpo/abnormalMorphologyOfAnatomicalEntityInLocation.tsv
@@ -0,0 +1 @@
+anatomical_entity	location	defined_class
diff --git a/src/curation/upheno-fillers/xpo/abnormalMorphologyOfPartOfAnatomicalEntity-modified.tsv b/src/curation/upheno-fillers/xpo/abnormalMorphologyOfPartOfAnatomicalEntity-modified.tsv
new file mode 100644
index 00000000..57c76cbb
--- /dev/null
+++ b/src/curation/upheno-fillers/xpo/abnormalMorphologyOfPartOfAnatomicalEntity-modified.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/xpo/abnormalNumberOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/xpo/abnormalNumberOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..cd61b297
--- /dev/null
+++ b/src/curation/upheno-fillers/xpo/abnormalNumberOfAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0011498
diff --git a/src/curation/upheno-fillers/xpo/abnormalShapeOfAnatomicalEntityByShapeType.tsv b/src/curation/upheno-fillers/xpo/abnormalShapeOfAnatomicalEntityByShapeType.tsv
new file mode 100644
index 00000000..6faff14f
--- /dev/null
+++ b/src/curation/upheno-fillers/xpo/abnormalShapeOfAnatomicalEntityByShapeType.tsv
@@ -0,0 +1,17 @@
+entity	shape	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0001796	http://purl.obolibrary.org/obo/UPHENO_0041170
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0001786	http://purl.obolibrary.org/obo/UPHENO_0041122
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0001784	http://purl.obolibrary.org/obo/UPHENO_0041123
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0041226
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0002285	http://purl.obolibrary.org/obo/UPHENO_0041762
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0002021	http://purl.obolibrary.org/obo/UPHENO_0041201
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0001879	http://purl.obolibrary.org/obo/UPHENO_0041629
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0001649	http://purl.obolibrary.org/obo/UPHENO_0041214
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0000617	http://purl.obolibrary.org/obo/UPHENO_0041234
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0002364	http://purl.obolibrary.org/obo/UPHENO_0041702
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0002034	http://purl.obolibrary.org/obo/UPHENO_0041373
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0001468	http://purl.obolibrary.org/obo/UPHENO_0041718
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0001875	http://purl.obolibrary.org/obo/UPHENO_0041221
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0001469	http://purl.obolibrary.org/obo/UPHENO_0041719
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0000404	http://purl.obolibrary.org/obo/UPHENO_0041206
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0001799	http://purl.obolibrary.org/obo/UPHENO_0041174
diff --git a/src/curation/upheno-fillers/xpo/abnormalShapeOfAnatomicalEntityByShapeTypeInLocation.tsv b/src/curation/upheno-fillers/xpo/abnormalShapeOfAnatomicalEntityByShapeTypeInLocation.tsv
new file mode 100644
index 00000000..62126e0c
--- /dev/null
+++ b/src/curation/upheno-fillers/xpo/abnormalShapeOfAnatomicalEntityByShapeTypeInLocation.tsv
@@ -0,0 +1 @@
+anatomical_entity	location	shape	defined_class
diff --git a/src/curation/upheno-fillers/xpo/abnormalWeightOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/xpo/abnormalWeightOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..e1eff1cc
--- /dev/null
+++ b/src/curation/upheno-fillers/xpo/abnormalWeightOfAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0010763
diff --git a/src/curation/upheno-fillers/xpo/abnormallyArrestedBiologicalProcess.tsv b/src/curation/upheno-fillers/xpo/abnormallyArrestedBiologicalProcess.tsv
new file mode 100644
index 00000000..20c653df
--- /dev/null
+++ b/src/curation/upheno-fillers/xpo/abnormallyArrestedBiologicalProcess.tsv
@@ -0,0 +1,5 @@
+biological_process	defined_class
+http://purl.obolibrary.org/obo/GO_0003401	http://purl.obolibrary.org/obo/UPHENO_0018651
+http://purl.obolibrary.org/obo/GO_0032502	http://purl.obolibrary.org/obo/UPHENO_0018610
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UPHENO_0018635
+http://purl.obolibrary.org/obo/GO_0007552	http://purl.obolibrary.org/obo/UPHENO_0080552
diff --git a/src/curation/upheno-fillers/xpo/abnormallyBentAnatomicalEntity.tsv b/src/curation/upheno-fillers/xpo/abnormallyBentAnatomicalEntity.tsv
new file mode 100644
index 00000000..39b4985e
--- /dev/null
+++ b/src/curation/upheno-fillers/xpo/abnormallyBentAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0074399
diff --git a/src/curation/upheno-fillers/xpo/abnormallyClosedAnatomicalEntity.tsv b/src/curation/upheno-fillers/xpo/abnormallyClosedAnatomicalEntity.tsv
new file mode 100644
index 00000000..dec31fb3
--- /dev/null
+++ b/src/curation/upheno-fillers/xpo/abnormallyClosedAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0074228
diff --git a/src/curation/upheno-fillers/xpo/abnormallyCurvedAnatomicalEntityByOrientation.tsv b/src/curation/upheno-fillers/xpo/abnormallyCurvedAnatomicalEntityByOrientation.tsv
new file mode 100644
index 00000000..1675636c
--- /dev/null
+++ b/src/curation/upheno-fillers/xpo/abnormallyCurvedAnatomicalEntityByOrientation.tsv
@@ -0,0 +1,5 @@
+anatomical_entity	orientation	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0001649	http://purl.obolibrary.org/obo/UPHENO_0031253
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0000406	http://purl.obolibrary.org/obo/UPHENO_0031193
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0001468	http://purl.obolibrary.org/obo/UPHENO_0031363
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0001469	http://purl.obolibrary.org/obo/UPHENO_0031365
diff --git a/src/curation/upheno-fillers/xpo/abnormallyDecreasedCoilingOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/xpo/abnormallyDecreasedCoilingOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..95729bd7
--- /dev/null
+++ b/src/curation/upheno-fillers/xpo/abnormallyDecreasedCoilingOfAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0079498
diff --git a/src/curation/upheno-fillers/xpo/abnormallyDecreasedHeightOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/xpo/abnormallyDecreasedHeightOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..4ec56f74
--- /dev/null
+++ b/src/curation/upheno-fillers/xpo/abnormallyDecreasedHeightOfAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0080351
diff --git a/src/curation/upheno-fillers/xpo/abnormallyDecreasedLengthOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/xpo/abnormallyDecreasedLengthOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..c661e30a
--- /dev/null
+++ b/src/curation/upheno-fillers/xpo/abnormallyDecreasedLengthOfAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0046505
diff --git a/src/curation/upheno-fillers/xpo/abnormallyDecreasedLengthOfAnatomicalEntityInLocation.tsv b/src/curation/upheno-fillers/xpo/abnormallyDecreasedLengthOfAnatomicalEntityInLocation.tsv
new file mode 100644
index 00000000..b7121acc
--- /dev/null
+++ b/src/curation/upheno-fillers/xpo/abnormallyDecreasedLengthOfAnatomicalEntityInLocation.tsv
@@ -0,0 +1 @@
+anatomical_entity	location	defined_class
diff --git a/src/curation/upheno-fillers/xpo/abnormallyDecreasedMassOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/xpo/abnormallyDecreasedMassOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..a9eec4ec
--- /dev/null
+++ b/src/curation/upheno-fillers/xpo/abnormallyDecreasedMassOfAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0082761
diff --git a/src/curation/upheno-fillers/xpo/abnormallyDecreasedMobilityOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/xpo/abnormallyDecreasedMobilityOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..ca81007f
--- /dev/null
+++ b/src/curation/upheno-fillers/xpo/abnormallyDecreasedMobilityOfAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0076671
diff --git a/src/curation/upheno-fillers/xpo/abnormallyDecreasedNumberOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/xpo/abnormallyDecreasedNumberOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..c057f89c
--- /dev/null
+++ b/src/curation/upheno-fillers/xpo/abnormallyDecreasedNumberOfAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0063722
diff --git a/src/curation/upheno-fillers/xpo/abnormallyDecreasedNumberOfAnatomicalEntityInLocation.tsv b/src/curation/upheno-fillers/xpo/abnormallyDecreasedNumberOfAnatomicalEntityInLocation.tsv
new file mode 100644
index 00000000..b7121acc
--- /dev/null
+++ b/src/curation/upheno-fillers/xpo/abnormallyDecreasedNumberOfAnatomicalEntityInLocation.tsv
@@ -0,0 +1 @@
+anatomical_entity	location	defined_class
diff --git a/src/curation/upheno-fillers/xpo/abnormallyDecreasedOccurrenceOfBiologicalProcess.tsv b/src/curation/upheno-fillers/xpo/abnormallyDecreasedOccurrenceOfBiologicalProcess.tsv
new file mode 100644
index 00000000..24f802df
--- /dev/null
+++ b/src/curation/upheno-fillers/xpo/abnormallyDecreasedOccurrenceOfBiologicalProcess.tsv
@@ -0,0 +1,5 @@
+biological_process	defined_class
+http://purl.obolibrary.org/obo/GO_0007626	http://purl.obolibrary.org/obo/UPHENO_0077431
+http://purl.obolibrary.org/obo/GO_0036269	http://purl.obolibrary.org/obo/UPHENO_0077432
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UPHENO_0077429
+http://purl.obolibrary.org/obo/GO_0007631	http://purl.obolibrary.org/obo/UPHENO_0077433
diff --git a/src/curation/upheno-fillers/xpo/abnormallyDecreasedOccurrenceOfBiologicalProcessInLocation.tsv b/src/curation/upheno-fillers/xpo/abnormallyDecreasedOccurrenceOfBiologicalProcessInLocation.tsv
new file mode 100644
index 00000000..1ff90430
--- /dev/null
+++ b/src/curation/upheno-fillers/xpo/abnormallyDecreasedOccurrenceOfBiologicalProcessInLocation.tsv
@@ -0,0 +1 @@
+biological_process	location	defined_class
diff --git a/src/curation/upheno-fillers/xpo/abnormallyDecreasedPigmentationOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/xpo/abnormallyDecreasedPigmentationOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..546f08b6
--- /dev/null
+++ b/src/curation/upheno-fillers/xpo/abnormallyDecreasedPigmentationOfAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0018526
diff --git a/src/curation/upheno-fillers/xpo/abnormallyDecreasedQualityOfBiologicalProcess.tsv b/src/curation/upheno-fillers/xpo/abnormallyDecreasedQualityOfBiologicalProcess.tsv
new file mode 100644
index 00000000..361b8682
--- /dev/null
+++ b/src/curation/upheno-fillers/xpo/abnormallyDecreasedQualityOfBiologicalProcess.tsv
@@ -0,0 +1,3 @@
+biological_process	defined_class
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UPHENO_0052178
+http://purl.obolibrary.org/obo/GO_0042692	http://purl.obolibrary.org/obo/UPHENO_0079485
diff --git a/src/curation/upheno-fillers/xpo/abnormallyDecreasedQualityOfBiologicalProcessInLocation.tsv b/src/curation/upheno-fillers/xpo/abnormallyDecreasedQualityOfBiologicalProcessInLocation.tsv
new file mode 100644
index 00000000..1ff90430
--- /dev/null
+++ b/src/curation/upheno-fillers/xpo/abnormallyDecreasedQualityOfBiologicalProcessInLocation.tsv
@@ -0,0 +1 @@
+biological_process	location	defined_class
diff --git a/src/curation/upheno-fillers/xpo/abnormallyDecreasedRateOfBiologicalProcess.tsv b/src/curation/upheno-fillers/xpo/abnormallyDecreasedRateOfBiologicalProcess.tsv
new file mode 100644
index 00000000..14c407c8
--- /dev/null
+++ b/src/curation/upheno-fillers/xpo/abnormallyDecreasedRateOfBiologicalProcess.tsv
@@ -0,0 +1,4 @@
+biological_process	defined_class
+http://purl.obolibrary.org/obo/GO_0071929	http://purl.obolibrary.org/obo/UPHENO_0076902
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UPHENO_0005433
+http://purl.obolibrary.org/obo/GO_0007552	http://purl.obolibrary.org/obo/UPHENO_0080288
diff --git a/src/curation/upheno-fillers/xpo/abnormallyDecreasedRateOfBiologicalProcessInLocation.tsv b/src/curation/upheno-fillers/xpo/abnormallyDecreasedRateOfBiologicalProcessInLocation.tsv
new file mode 100644
index 00000000..1ff90430
--- /dev/null
+++ b/src/curation/upheno-fillers/xpo/abnormallyDecreasedRateOfBiologicalProcessInLocation.tsv
@@ -0,0 +1 @@
+biological_process	location	defined_class
diff --git a/src/curation/upheno-fillers/xpo/abnormallyDecreasedRateOfMolecularFunction.tsv b/src/curation/upheno-fillers/xpo/abnormallyDecreasedRateOfMolecularFunction.tsv
new file mode 100644
index 00000000..4f887c78
--- /dev/null
+++ b/src/curation/upheno-fillers/xpo/abnormallyDecreasedRateOfMolecularFunction.tsv
@@ -0,0 +1,15 @@
+molecular_function	defined_class
+http://purl.obolibrary.org/obo/GO_0016829	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0004197	http://purl.obolibrary.org/obo/UPHENO_0077199
+http://purl.obolibrary.org/obo/GO_0003674	http://purl.obolibrary.org/obo/UPHENO_0066865
+http://purl.obolibrary.org/obo/GO_0004711	http://purl.obolibrary.org/obo/UPHENO_0077200
+http://purl.obolibrary.org/obo/GO_0004707	http://purl.obolibrary.org/obo/UPHENO_0077198
+http://purl.obolibrary.org/obo/GO_0003824	http://purl.obolibrary.org/obo/UPHENO_0066897
+http://purl.obolibrary.org/obo/GO_0032451	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0016491	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0016740	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0009975	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0016787	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0016853	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0016874	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0061783	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/xpo/abnormallyDecreasedSizeOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/xpo/abnormallyDecreasedSizeOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..f764e9f0
--- /dev/null
+++ b/src/curation/upheno-fillers/xpo/abnormallyDecreasedSizeOfAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0068971
diff --git a/src/curation/upheno-fillers/xpo/abnormallyDecreasedSizeOfAnatomicalEntityInLocation.tsv b/src/curation/upheno-fillers/xpo/abnormallyDecreasedSizeOfAnatomicalEntityInLocation.tsv
new file mode 100644
index 00000000..b7121acc
--- /dev/null
+++ b/src/curation/upheno-fillers/xpo/abnormallyDecreasedSizeOfAnatomicalEntityInLocation.tsv
@@ -0,0 +1 @@
+anatomical_entity	location	defined_class
diff --git a/src/curation/upheno-fillers/xpo/abnormallyDecreasedThicknessOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/xpo/abnormallyDecreasedThicknessOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..20af83a4
--- /dev/null
+++ b/src/curation/upheno-fillers/xpo/abnormallyDecreasedThicknessOfAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0080790
diff --git a/src/curation/upheno-fillers/xpo/abnormallyDecreasedVolumeOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/xpo/abnormallyDecreasedVolumeOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..5a65c101
--- /dev/null
+++ b/src/curation/upheno-fillers/xpo/abnormallyDecreasedVolumeOfAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0078429
diff --git a/src/curation/upheno-fillers/xpo/abnormallyDecreasedWeightOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/xpo/abnormallyDecreasedWeightOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..3234483e
--- /dev/null
+++ b/src/curation/upheno-fillers/xpo/abnormallyDecreasedWeightOfAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0054261
diff --git a/src/curation/upheno-fillers/xpo/abnormallyDecreasedWidthOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/xpo/abnormallyDecreasedWidthOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..f99bd232
--- /dev/null
+++ b/src/curation/upheno-fillers/xpo/abnormallyDecreasedWidthOfAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0054567
diff --git a/src/curation/upheno-fillers/xpo/abnormallyDecreasedWidthOfAnatomicalEntityInLocation.tsv b/src/curation/upheno-fillers/xpo/abnormallyDecreasedWidthOfAnatomicalEntityInLocation.tsv
new file mode 100644
index 00000000..b7121acc
--- /dev/null
+++ b/src/curation/upheno-fillers/xpo/abnormallyDecreasedWidthOfAnatomicalEntityInLocation.tsv
@@ -0,0 +1 @@
+anatomical_entity	location	defined_class
diff --git a/src/curation/upheno-fillers/xpo/abnormallyDelayedBiologicalProcess.tsv b/src/curation/upheno-fillers/xpo/abnormallyDelayedBiologicalProcess.tsv
new file mode 100644
index 00000000..bf81e50e
--- /dev/null
+++ b/src/curation/upheno-fillers/xpo/abnormallyDelayedBiologicalProcess.tsv
@@ -0,0 +1,4 @@
+biological_process	defined_class
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UPHENO_0000543
+http://purl.obolibrary.org/obo/GO_0009790	http://purl.obolibrary.org/obo/UPHENO_0000869
+http://purl.obolibrary.org/obo/GO_0007552	http://purl.obolibrary.org/obo/UPHENO_0080537
diff --git a/src/curation/upheno-fillers/xpo/abnormallyDilatedAnatomicalEntity.tsv b/src/curation/upheno-fillers/xpo/abnormallyDilatedAnatomicalEntity.tsv
new file mode 100644
index 00000000..6e1084c2
--- /dev/null
+++ b/src/curation/upheno-fillers/xpo/abnormallyDilatedAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0084124
diff --git a/src/curation/upheno-fillers/xpo/abnormallyDuplicatedAnatomicalEntity.tsv b/src/curation/upheno-fillers/xpo/abnormallyDuplicatedAnatomicalEntity.tsv
new file mode 100644
index 00000000..ce51d6c8
--- /dev/null
+++ b/src/curation/upheno-fillers/xpo/abnormallyDuplicatedAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0075340
diff --git a/src/curation/upheno-fillers/xpo/abnormallyDuplicatedAnatomicalEntityInLocation.tsv b/src/curation/upheno-fillers/xpo/abnormallyDuplicatedAnatomicalEntityInLocation.tsv
new file mode 100644
index 00000000..b7121acc
--- /dev/null
+++ b/src/curation/upheno-fillers/xpo/abnormallyDuplicatedAnatomicalEntityInLocation.tsv
@@ -0,0 +1 @@
+anatomical_entity	location	defined_class
diff --git a/src/curation/upheno-fillers/xpo/abnormallyFusedAnatomicalEntities.tsv b/src/curation/upheno-fillers/xpo/abnormallyFusedAnatomicalEntities.tsv
new file mode 100644
index 00000000..6363a024
--- /dev/null
+++ b/src/curation/upheno-fillers/xpo/abnormallyFusedAnatomicalEntities.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	anatomical_entity_fused_with	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0078125
diff --git a/src/curation/upheno-fillers/xpo/abnormallyFusedAnatomicalEntitiesInLocation.tsv b/src/curation/upheno-fillers/xpo/abnormallyFusedAnatomicalEntitiesInLocation.tsv
new file mode 100644
index 00000000..e0353c20
--- /dev/null
+++ b/src/curation/upheno-fillers/xpo/abnormallyFusedAnatomicalEntitiesInLocation.tsv
@@ -0,0 +1 @@
+anatomical_entity	anatomical_entity_fused_with	location	location_fused_with	defined_class
diff --git a/src/curation/upheno-fillers/xpo/abnormallyIncompleteClosureOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/xpo/abnormallyIncompleteClosureOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..dc495ee7
--- /dev/null
+++ b/src/curation/upheno-fillers/xpo/abnormallyIncompleteClosureOfAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0033572
diff --git a/src/curation/upheno-fillers/xpo/abnormallyIncreasedHeightOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/xpo/abnormallyIncreasedHeightOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..b4b43407
--- /dev/null
+++ b/src/curation/upheno-fillers/xpo/abnormallyIncreasedHeightOfAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0063513
diff --git a/src/curation/upheno-fillers/xpo/abnormallyIncreasedLengthOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/xpo/abnormallyIncreasedLengthOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..b9cad5a7
--- /dev/null
+++ b/src/curation/upheno-fillers/xpo/abnormallyIncreasedLengthOfAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0072195
diff --git a/src/curation/upheno-fillers/xpo/abnormallyIncreasedMobilityOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/xpo/abnormallyIncreasedMobilityOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..8d6a89d0
--- /dev/null
+++ b/src/curation/upheno-fillers/xpo/abnormallyIncreasedMobilityOfAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0077419
diff --git a/src/curation/upheno-fillers/xpo/abnormallyIncreasedNumberOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/xpo/abnormallyIncreasedNumberOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..c6cfd6eb
--- /dev/null
+++ b/src/curation/upheno-fillers/xpo/abnormallyIncreasedNumberOfAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0014240
diff --git a/src/curation/upheno-fillers/xpo/abnormallyIncreasedNumberOfAnatomicalEntityInLocation.tsv b/src/curation/upheno-fillers/xpo/abnormallyIncreasedNumberOfAnatomicalEntityInLocation.tsv
new file mode 100644
index 00000000..b7121acc
--- /dev/null
+++ b/src/curation/upheno-fillers/xpo/abnormallyIncreasedNumberOfAnatomicalEntityInLocation.tsv
@@ -0,0 +1 @@
+anatomical_entity	location	defined_class
diff --git a/src/curation/upheno-fillers/xpo/abnormallyIncreasedOccurrenceOfBiologicalProcess.tsv b/src/curation/upheno-fillers/xpo/abnormallyIncreasedOccurrenceOfBiologicalProcess.tsv
new file mode 100644
index 00000000..e4eafade
--- /dev/null
+++ b/src/curation/upheno-fillers/xpo/abnormallyIncreasedOccurrenceOfBiologicalProcess.tsv
@@ -0,0 +1,5 @@
+biological_process	defined_class
+http://purl.obolibrary.org/obo/GO_0007626	http://purl.obolibrary.org/obo/UPHENO_0079249
+http://purl.obolibrary.org/obo/GO_0036269	http://purl.obolibrary.org/obo/UPHENO_0079250
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UPHENO_0079251
+http://purl.obolibrary.org/obo/GO_0007631	http://purl.obolibrary.org/obo/UPHENO_0079252
diff --git a/src/curation/upheno-fillers/xpo/abnormallyIncreasedOccurrenceOfBiologicalProcessInLocation.tsv b/src/curation/upheno-fillers/xpo/abnormallyIncreasedOccurrenceOfBiologicalProcessInLocation.tsv
new file mode 100644
index 00000000..1ff90430
--- /dev/null
+++ b/src/curation/upheno-fillers/xpo/abnormallyIncreasedOccurrenceOfBiologicalProcessInLocation.tsv
@@ -0,0 +1 @@
+biological_process	location	defined_class
diff --git a/src/curation/upheno-fillers/xpo/abnormallyIncreasedPigmentationOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/xpo/abnormallyIncreasedPigmentationOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..3715f319
--- /dev/null
+++ b/src/curation/upheno-fillers/xpo/abnormallyIncreasedPigmentationOfAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0010666
diff --git a/src/curation/upheno-fillers/xpo/abnormallyIncreasedRateOfBiologicalProcess.tsv b/src/curation/upheno-fillers/xpo/abnormallyIncreasedRateOfBiologicalProcess.tsv
new file mode 100644
index 00000000..9245d15b
--- /dev/null
+++ b/src/curation/upheno-fillers/xpo/abnormallyIncreasedRateOfBiologicalProcess.tsv
@@ -0,0 +1,5 @@
+biological_process	defined_class
+http://purl.obolibrary.org/obo/GO_0008283	http://purl.obolibrary.org/obo/UPHENO_0055106
+http://purl.obolibrary.org/obo/GO_0071929	http://purl.obolibrary.org/obo/UPHENO_0076678
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UPHENO_0054970
+http://purl.obolibrary.org/obo/GO_0007552	http://purl.obolibrary.org/obo/UPHENO_0082828
diff --git a/src/curation/upheno-fillers/xpo/abnormallyIncreasedRateOfBiologicalProcessInLocation.tsv b/src/curation/upheno-fillers/xpo/abnormallyIncreasedRateOfBiologicalProcessInLocation.tsv
new file mode 100644
index 00000000..1ff90430
--- /dev/null
+++ b/src/curation/upheno-fillers/xpo/abnormallyIncreasedRateOfBiologicalProcessInLocation.tsv
@@ -0,0 +1 @@
+biological_process	location	defined_class
diff --git a/src/curation/upheno-fillers/xpo/abnormallyIncreasedRateOfMolecularFunction.tsv b/src/curation/upheno-fillers/xpo/abnormallyIncreasedRateOfMolecularFunction.tsv
new file mode 100644
index 00000000..7ede87df
--- /dev/null
+++ b/src/curation/upheno-fillers/xpo/abnormallyIncreasedRateOfMolecularFunction.tsv
@@ -0,0 +1,15 @@
+molecular_function	defined_class
+http://purl.obolibrary.org/obo/GO_0016829	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0004197	http://purl.obolibrary.org/obo/UPHENO_0048685
+http://purl.obolibrary.org/obo/GO_0003674	http://purl.obolibrary.org/obo/UPHENO_0048661
+http://purl.obolibrary.org/obo/GO_0004711	http://purl.obolibrary.org/obo/UPHENO_0080006
+http://purl.obolibrary.org/obo/GO_0004707	http://purl.obolibrary.org/obo/UPHENO_0080005
+http://purl.obolibrary.org/obo/GO_0003824	http://purl.obolibrary.org/obo/UPHENO_0048683
+http://purl.obolibrary.org/obo/GO_0032451	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0016491	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0016740	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0009975	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0016787	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0016853	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0016874	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0061783	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/xpo/abnormallyIncreasedSizeOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/xpo/abnormallyIncreasedSizeOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..14f0e520
--- /dev/null
+++ b/src/curation/upheno-fillers/xpo/abnormallyIncreasedSizeOfAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0001072
diff --git a/src/curation/upheno-fillers/xpo/abnormallyIncreasedSizeOfAnatomicalEntityInLocation.tsv b/src/curation/upheno-fillers/xpo/abnormallyIncreasedSizeOfAnatomicalEntityInLocation.tsv
new file mode 100644
index 00000000..b7121acc
--- /dev/null
+++ b/src/curation/upheno-fillers/xpo/abnormallyIncreasedSizeOfAnatomicalEntityInLocation.tsv
@@ -0,0 +1 @@
+anatomical_entity	location	defined_class
diff --git a/src/curation/upheno-fillers/xpo/abnormallyIncreasedThicknessOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/xpo/abnormallyIncreasedThicknessOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..0ca1e044
--- /dev/null
+++ b/src/curation/upheno-fillers/xpo/abnormallyIncreasedThicknessOfAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0047821
diff --git a/src/curation/upheno-fillers/xpo/abnormallyIncreasedThicknessOfAnatomicalEntityInLocation.tsv b/src/curation/upheno-fillers/xpo/abnormallyIncreasedThicknessOfAnatomicalEntityInLocation.tsv
new file mode 100644
index 00000000..b7121acc
--- /dev/null
+++ b/src/curation/upheno-fillers/xpo/abnormallyIncreasedThicknessOfAnatomicalEntityInLocation.tsv
@@ -0,0 +1 @@
+anatomical_entity	location	defined_class
diff --git a/src/curation/upheno-fillers/xpo/abnormallyIncreasedVolumeOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/xpo/abnormallyIncreasedVolumeOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..71147114
--- /dev/null
+++ b/src/curation/upheno-fillers/xpo/abnormallyIncreasedVolumeOfAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0084715
diff --git a/src/curation/upheno-fillers/xpo/abnormallyIncreasedWeightOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/xpo/abnormallyIncreasedWeightOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..f603c0cf
--- /dev/null
+++ b/src/curation/upheno-fillers/xpo/abnormallyIncreasedWeightOfAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0008273
diff --git a/src/curation/upheno-fillers/xpo/abnormallyIncreasedWidthOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/xpo/abnormallyIncreasedWidthOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..a0f1a8f6
--- /dev/null
+++ b/src/curation/upheno-fillers/xpo/abnormallyIncreasedWidthOfAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0006161
diff --git a/src/curation/upheno-fillers/xpo/abnormallyIncreasedWidthOfAnatomicalEntityInLocation.tsv b/src/curation/upheno-fillers/xpo/abnormallyIncreasedWidthOfAnatomicalEntityInLocation.tsv
new file mode 100644
index 00000000..b7121acc
--- /dev/null
+++ b/src/curation/upheno-fillers/xpo/abnormallyIncreasedWidthOfAnatomicalEntityInLocation.tsv
@@ -0,0 +1 @@
+anatomical_entity	location	defined_class
diff --git a/src/curation/upheno-fillers/xpo/abnormallyInvertedAnatomicalEntityInLocation.tsv b/src/curation/upheno-fillers/xpo/abnormallyInvertedAnatomicalEntityInLocation.tsv
new file mode 100644
index 00000000..b7121acc
--- /dev/null
+++ b/src/curation/upheno-fillers/xpo/abnormallyInvertedAnatomicalEntityInLocation.tsv
@@ -0,0 +1 @@
+anatomical_entity	location	defined_class
diff --git a/src/curation/upheno-fillers/xpo/abnormallyOpenAnatomicalEntity.tsv b/src/curation/upheno-fillers/xpo/abnormallyOpenAnatomicalEntity.tsv
new file mode 100644
index 00000000..c504ed48
--- /dev/null
+++ b/src/curation/upheno-fillers/xpo/abnormallyOpenAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0075655
diff --git a/src/curation/upheno-fillers/xpo/abnormallyPrematureBiologicalProcess.tsv b/src/curation/upheno-fillers/xpo/abnormallyPrematureBiologicalProcess.tsv
new file mode 100644
index 00000000..84501121
--- /dev/null
+++ b/src/curation/upheno-fillers/xpo/abnormallyPrematureBiologicalProcess.tsv
@@ -0,0 +1,3 @@
+biological_process	defined_class
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UPHENO_0049440
+http://purl.obolibrary.org/obo/GO_0007552	http://purl.obolibrary.org/obo/UPHENO_0080421
diff --git a/src/curation/upheno-fillers/xpo/abnormallyProtrudingAnatomicalEntity.tsv b/src/curation/upheno-fillers/xpo/abnormallyProtrudingAnatomicalEntity.tsv
new file mode 100644
index 00000000..57c76cbb
--- /dev/null
+++ b/src/curation/upheno-fillers/xpo/abnormallyProtrudingAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/xpo/abnormallySegmentedAnatomicalEntityInLocation.tsv b/src/curation/upheno-fillers/xpo/abnormallySegmentedAnatomicalEntityInLocation.tsv
new file mode 100644
index 00000000..b7121acc
--- /dev/null
+++ b/src/curation/upheno-fillers/xpo/abnormallySegmentedAnatomicalEntityInLocation.tsv
@@ -0,0 +1 @@
+anatomical_entity	location	defined_class
diff --git a/src/curation/upheno-fillers/xpo/bifurcatedAnatomicalEntity.tsv b/src/curation/upheno-fillers/xpo/bifurcatedAnatomicalEntity.tsv
new file mode 100644
index 00000000..3ebc6585
--- /dev/null
+++ b/src/curation/upheno-fillers/xpo/bifurcatedAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0055805
diff --git a/src/curation/upheno-fillers/xpo/bifurcatedAnatomicalEntityInLocation.tsv b/src/curation/upheno-fillers/xpo/bifurcatedAnatomicalEntityInLocation.tsv
new file mode 100644
index 00000000..b7121acc
--- /dev/null
+++ b/src/curation/upheno-fillers/xpo/bifurcatedAnatomicalEntityInLocation.tsv
@@ -0,0 +1 @@
+anatomical_entity	location	defined_class
diff --git a/src/curation/upheno-fillers/xpo/disorganizedAnatomicalEntity.tsv b/src/curation/upheno-fillers/xpo/disorganizedAnatomicalEntity.tsv
new file mode 100644
index 00000000..86f147d1
--- /dev/null
+++ b/src/curation/upheno-fillers/xpo/disorganizedAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0084685
diff --git a/src/curation/upheno-fillers/xpo/edematousAnatomicalEntity.tsv b/src/curation/upheno-fillers/xpo/edematousAnatomicalEntity.tsv
new file mode 100644
index 00000000..b9751032
--- /dev/null
+++ b/src/curation/upheno-fillers/xpo/edematousAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0082498
diff --git a/src/curation/upheno-fillers/xpo/malformedAnatomicalEntityByType.tsv b/src/curation/upheno-fillers/xpo/malformedAnatomicalEntityByType.tsv
new file mode 100644
index 00000000..a7110691
--- /dev/null
+++ b/src/curation/upheno-fillers/xpo/malformedAnatomicalEntityByType.tsv
@@ -0,0 +1,18 @@
+anatomical_entity	malformed	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0000646	http://purl.obolibrary.org/obo/UPHENO_0076957
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0030010	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0030005	http://purl.obolibrary.org/obo/UPHENO_0076958
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0030004	http://purl.obolibrary.org/obo/UPHENO_0076959
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0030001	http://purl.obolibrary.org/obo/UPHENO_0076960
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0030012	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0030000	http://purl.obolibrary.org/obo/UPHENO_0076961
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0030007	http://purl.obolibrary.org/obo/UPHENO_0076962
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0030006	http://purl.obolibrary.org/obo/UPHENO_0076963
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0000630	http://purl.obolibrary.org/obo/UPHENO_0076964
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0000620	http://purl.obolibrary.org/obo/UPHENO_0076965
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0030003	http://purl.obolibrary.org/obo/UPHENO_0076966
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0000636	http://purl.obolibrary.org/obo/UPHENO_0076967
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0030002	http://purl.obolibrary.org/obo/UPHENO_0076968
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0000615	http://purl.obolibrary.org/obo/UPHENO_0076969
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0030013	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0030009	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/xpo/metaplasticAnatomicalEntity.tsv b/src/curation/upheno-fillers/xpo/metaplasticAnatomicalEntity.tsv
new file mode 100644
index 00000000..c41e002a
--- /dev/null
+++ b/src/curation/upheno-fillers/xpo/metaplasticAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0080376
diff --git a/src/curation/upheno-fillers/xpo/mislocalisedAnatomicalEntity.tsv b/src/curation/upheno-fillers/xpo/mislocalisedAnatomicalEntity.tsv
new file mode 100644
index 00000000..32fe049b
--- /dev/null
+++ b/src/curation/upheno-fillers/xpo/mislocalisedAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0053580
diff --git a/src/curation/upheno-fillers/xpo/mislocalisedAnatomicalEntityInLocation.tsv b/src/curation/upheno-fillers/xpo/mislocalisedAnatomicalEntityInLocation.tsv
new file mode 100644
index 00000000..b7121acc
--- /dev/null
+++ b/src/curation/upheno-fillers/xpo/mislocalisedAnatomicalEntityInLocation.tsv
@@ -0,0 +1 @@
+anatomical_entity	location	defined_class
diff --git a/src/curation/upheno-fillers/xpo/necroticAnatomicalEntity.tsv b/src/curation/upheno-fillers/xpo/necroticAnatomicalEntity.tsv
new file mode 100644
index 00000000..0d65a24a
--- /dev/null
+++ b/src/curation/upheno-fillers/xpo/necroticAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0081698
diff --git a/src/curation/upheno-fillers/xpo/neoplasticAnatomicalEntity.tsv b/src/curation/upheno-fillers/xpo/neoplasticAnatomicalEntity.tsv
new file mode 100644
index 00000000..6cc392b9
--- /dev/null
+++ b/src/curation/upheno-fillers/xpo/neoplasticAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0081769
diff --git a/src/curation/upheno-fillers/xpo/paralysedAnatomicalEntity.tsv b/src/curation/upheno-fillers/xpo/paralysedAnatomicalEntity.tsv
new file mode 100644
index 00000000..c3012971
--- /dev/null
+++ b/src/curation/upheno-fillers/xpo/paralysedAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0081700
diff --git a/src/curation/upheno-fillers/zp/abnormalAbsenceOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/zp/abnormalAbsenceOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..8185662f
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormalAbsenceOfAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0008523
diff --git a/src/curation/upheno-fillers/zp/abnormalAbsenceOfAnatomicalEntityDueToDegeneration.tsv b/src/curation/upheno-fillers/zp/abnormalAbsenceOfAnatomicalEntityDueToDegeneration.tsv
new file mode 100644
index 00000000..9b835cb6
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormalAbsenceOfAnatomicalEntityDueToDegeneration.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0046054
diff --git a/src/curation/upheno-fillers/zp/abnormalAbsenceOfAnatomicalEntityInLocation.tsv b/src/curation/upheno-fillers/zp/abnormalAbsenceOfAnatomicalEntityInLocation.tsv
new file mode 100644
index 00000000..b7121acc
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormalAbsenceOfAnatomicalEntityInLocation.tsv
@@ -0,0 +1 @@
+anatomical_entity	location	defined_class
diff --git a/src/curation/upheno-fillers/zp/abnormalAbsenceOfBiologicalProcess.tsv b/src/curation/upheno-fillers/zp/abnormalAbsenceOfBiologicalProcess.tsv
new file mode 100644
index 00000000..7d70ba89
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormalAbsenceOfBiologicalProcess.tsv
@@ -0,0 +1,24 @@
+biological_process	defined_class
+http://purl.obolibrary.org/obo/GO_0007634	http://purl.obolibrary.org/obo/UPHENO_0078490
+http://purl.obolibrary.org/obo/GO_0007601	http://purl.obolibrary.org/obo/UPHENO_0078456
+http://purl.obolibrary.org/obo/GO_0046660	http://purl.obolibrary.org/obo/UPHENO_0078505
+http://purl.obolibrary.org/obo/GO_0051301	http://purl.obolibrary.org/obo/UPHENO_0034038
+http://purl.obolibrary.org/obo/GO_0030866	http://purl.obolibrary.org/obo/UPHENO_0078506
+http://purl.obolibrary.org/obo/GO_0086005	http://purl.obolibrary.org/obo/UPHENO_0078507
+http://purl.obolibrary.org/obo/GO_0007632	http://purl.obolibrary.org/obo/UPHENO_0078496
+http://purl.obolibrary.org/obo/GO_0008015	http://purl.obolibrary.org/obo/UPHENO_0078508
+http://purl.obolibrary.org/obo/GO_0050802	http://purl.obolibrary.org/obo/UPHENO_0078509
+http://purl.obolibrary.org/obo/GO_0008345	http://purl.obolibrary.org/obo/UPHENO_0078510
+http://purl.obolibrary.org/obo/GO_0060215	http://purl.obolibrary.org/obo/UPHENO_0078511
+http://purl.obolibrary.org/obo/GO_0060005	http://purl.obolibrary.org/obo/UPHENO_0078512
+http://purl.obolibrary.org/obo/GO_0061515	http://purl.obolibrary.org/obo/UPHENO_0078513
+http://purl.obolibrary.org/obo/GO_0008283	http://purl.obolibrary.org/obo/UPHENO_0078514
+http://purl.obolibrary.org/obo/GO_0042407	http://purl.obolibrary.org/obo/UPHENO_0078515
+http://purl.obolibrary.org/obo/GO_0036269	http://purl.obolibrary.org/obo/UPHENO_0078499
+http://purl.obolibrary.org/obo/GO_0009652	http://purl.obolibrary.org/obo/UPHENO_0078516
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UPHENO_0034024
+http://purl.obolibrary.org/obo/GO_0060047	http://purl.obolibrary.org/obo/UPHENO_0078517
+http://purl.obolibrary.org/obo/GO_0001966	http://purl.obolibrary.org/obo/UPHENO_0078518
+http://purl.obolibrary.org/obo/GO_0003319	http://purl.obolibrary.org/obo/UPHENO_0078519
+http://purl.obolibrary.org/obo/GO_0003309	http://purl.obolibrary.org/obo/UPHENO_0078520
+http://purl.obolibrary.org/obo/GO_0001947	http://purl.obolibrary.org/obo/UPHENO_0078467
diff --git a/src/curation/upheno-fillers/zp/abnormalAbsenceOfBiologicalProcessInLocation.tsv b/src/curation/upheno-fillers/zp/abnormalAbsenceOfBiologicalProcessInLocation.tsv
new file mode 100644
index 00000000..1ff90430
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormalAbsenceOfBiologicalProcessInLocation.tsv
@@ -0,0 +1 @@
+biological_process	location	defined_class
diff --git a/src/curation/upheno-fillers/zp/abnormalAbsenceOfChemicalEntityInLocation.tsv b/src/curation/upheno-fillers/zp/abnormalAbsenceOfChemicalEntityInLocation.tsv
new file mode 100644
index 00000000..1aad9b8a
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormalAbsenceOfChemicalEntityInLocation.tsv
@@ -0,0 +1 @@
+chemical_entity	location	defined_class
diff --git a/src/curation/upheno-fillers/zp/abnormalAbsenceOfPigmentationOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/zp/abnormalAbsenceOfPigmentationOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..f9722607
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormalAbsenceOfPigmentationOfAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0008222
diff --git a/src/curation/upheno-fillers/zp/abnormalAgenesisOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/zp/abnormalAgenesisOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..86daa471
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormalAgenesisOfAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0080325
diff --git a/src/curation/upheno-fillers/zp/abnormalAnatomicalEntity.tsv b/src/curation/upheno-fillers/zp/abnormalAnatomicalEntity.tsv
new file mode 100644
index 00000000..ebe14380
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormalAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0002536
diff --git a/src/curation/upheno-fillers/zp/abnormalBiologicalProcess.tsv b/src/curation/upheno-fillers/zp/abnormalBiologicalProcess.tsv
new file mode 100644
index 00000000..250785f7
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormalBiologicalProcess.tsv
@@ -0,0 +1,969 @@
+biological_process	defined_class
+http://purl.obolibrary.org/obo/GO_0032922	http://purl.obolibrary.org/obo/UPHENO_0050885
+http://purl.obolibrary.org/obo/GO_0050976	http://purl.obolibrary.org/obo/UPHENO_0050206
+http://purl.obolibrary.org/obo/GO_0003146	http://purl.obolibrary.org/obo/UPHENO_0050886
+http://purl.obolibrary.org/obo/GO_0006898	http://purl.obolibrary.org/obo/UPHENO_0050207
+http://purl.obolibrary.org/obo/GO_0007501	http://purl.obolibrary.org/obo/UPHENO_0050887
+http://purl.obolibrary.org/obo/GO_0003147	http://purl.obolibrary.org/obo/UPHENO_0050888
+http://purl.obolibrary.org/obo/GO_0050975	http://purl.obolibrary.org/obo/UPHENO_0050208
+http://purl.obolibrary.org/obo/GO_0050973	http://purl.obolibrary.org/obo/UPHENO_0050210
+http://purl.obolibrary.org/obo/GO_0007507	http://purl.obolibrary.org/obo/UPHENO_0050138
+http://purl.obolibrary.org/obo/GO_1990266	http://purl.obolibrary.org/obo/UPHENO_0050211
+http://purl.obolibrary.org/obo/GO_0030509	http://purl.obolibrary.org/obo/UPHENO_0050213
+http://purl.obolibrary.org/obo/GO_0003140	http://purl.obolibrary.org/obo/UPHENO_0050893
+http://purl.obolibrary.org/obo/GO_0003143	http://purl.obolibrary.org/obo/UPHENO_0050895
+http://purl.obolibrary.org/obo/GO_0019722	http://purl.obolibrary.org/obo/UPHENO_0050214
+http://purl.obolibrary.org/obo/GO_0014036	http://purl.obolibrary.org/obo/UPHENO_0050215
+http://purl.obolibrary.org/obo/GO_0014033	http://purl.obolibrary.org/obo/UPHENO_0050216
+http://purl.obolibrary.org/obo/GO_0007509	http://purl.obolibrary.org/obo/UPHENO_0050898
+http://purl.obolibrary.org/obo/GO_0071892	http://purl.obolibrary.org/obo/UPHENO_0078697
+http://purl.obolibrary.org/obo/GO_0014032	http://purl.obolibrary.org/obo/UPHENO_0050156
+http://purl.obolibrary.org/obo/GO_0006401	http://purl.obolibrary.org/obo/UPHENO_0049611
+http://purl.obolibrary.org/obo/GO_0030510	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0006885	http://purl.obolibrary.org/obo/UPHENO_0049613
+http://purl.obolibrary.org/obo/GO_0050962	http://purl.obolibrary.org/obo/UPHENO_0050219
+http://purl.obolibrary.org/obo/GO_0048884	http://purl.obolibrary.org/obo/UPHENO_0050902
+http://purl.obolibrary.org/obo/GO_0003138	http://purl.obolibrary.org/obo/UPHENO_0050903
+http://purl.obolibrary.org/obo/GO_0048883	http://purl.obolibrary.org/obo/UPHENO_0050904
+http://purl.obolibrary.org/obo/GO_0003139	http://purl.obolibrary.org/obo/UPHENO_0050905
+http://purl.obolibrary.org/obo/GO_0048885	http://purl.obolibrary.org/obo/UPHENO_0050907
+http://purl.obolibrary.org/obo/GO_0048882	http://purl.obolibrary.org/obo/UPHENO_0050908
+http://purl.obolibrary.org/obo/GO_0002040	http://purl.obolibrary.org/obo/UPHENO_0050221
+http://purl.obolibrary.org/obo/GO_0002042	http://purl.obolibrary.org/obo/UPHENO_0050223
+http://purl.obolibrary.org/obo/GO_0006883	http://purl.obolibrary.org/obo/UPHENO_0050225
+http://purl.obolibrary.org/obo/GO_0002286	http://purl.obolibrary.org/obo/UPHENO_0078698
+http://purl.obolibrary.org/obo/GO_0045137	http://purl.obolibrary.org/obo/UPHENO_0050226
+http://purl.obolibrary.org/obo/GO_0002043	http://purl.obolibrary.org/obo/UPHENO_0050229
+http://purl.obolibrary.org/obo/GO_0016203	http://purl.obolibrary.org/obo/UPHENO_0049625
+http://purl.obolibrary.org/obo/GO_0060536	http://purl.obolibrary.org/obo/UPHENO_0050910
+http://purl.obolibrary.org/obo/GO_0014028	http://purl.obolibrary.org/obo/UPHENO_0050230
+http://purl.obolibrary.org/obo/GO_0014029	http://purl.obolibrary.org/obo/UPHENO_0050231
+http://purl.obolibrary.org/obo/GO_0019953	http://purl.obolibrary.org/obo/UPHENO_0050911
+http://purl.obolibrary.org/obo/GO_0036058	http://purl.obolibrary.org/obo/UPHENO_0050912
+http://purl.obolibrary.org/obo/GO_0014025	http://purl.obolibrary.org/obo/UPHENO_0080611
+http://purl.obolibrary.org/obo/GO_0014021	http://purl.obolibrary.org/obo/UPHENO_0050232
+http://purl.obolibrary.org/obo/GO_0060538	http://purl.obolibrary.org/obo/UPHENO_0050914
+http://purl.obolibrary.org/obo/GO_0061626	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0050953	http://purl.obolibrary.org/obo/UPHENO_0050236
+http://purl.obolibrary.org/obo/GO_0007528	http://purl.obolibrary.org/obo/UPHENO_0050917
+http://purl.obolibrary.org/obo/GO_0003161	http://purl.obolibrary.org/obo/UPHENO_0050918
+http://purl.obolibrary.org/obo/GO_0048870	http://purl.obolibrary.org/obo/UPHENO_0049634
+http://purl.obolibrary.org/obo/GO_0002072	http://purl.obolibrary.org/obo/UPHENO_0083068
+http://purl.obolibrary.org/obo/GO_0008610	http://purl.obolibrary.org/obo/UPHENO_0050240
+http://purl.obolibrary.org/obo/GO_0002075	http://purl.obolibrary.org/obo/UPHENO_0050241
+http://purl.obolibrary.org/obo/GO_0050957	http://purl.obolibrary.org/obo/UPHENO_0050242
+http://purl.obolibrary.org/obo/GO_0016236	http://purl.obolibrary.org/obo/UPHENO_0050243
+http://purl.obolibrary.org/obo/GO_0016477	http://purl.obolibrary.org/obo/UPHENO_0049643
+http://purl.obolibrary.org/obo/GO_0070306	http://purl.obolibrary.org/obo/UPHENO_0050919
+http://purl.obolibrary.org/obo/GO_0070309	http://purl.obolibrary.org/obo/UPHENO_0050920
+http://purl.obolibrary.org/obo/GO_0009948	http://purl.obolibrary.org/obo/UPHENO_0050184
+http://purl.obolibrary.org/obo/GO_0022904	http://purl.obolibrary.org/obo/UPHENO_0050246
+http://purl.obolibrary.org/obo/GO_0071632	http://purl.obolibrary.org/obo/UPHENO_0050921
+http://purl.obolibrary.org/obo/GO_0030534	http://purl.obolibrary.org/obo/UPHENO_0049650
+http://purl.obolibrary.org/obo/GO_0003157	http://purl.obolibrary.org/obo/UPHENO_0050922
+http://purl.obolibrary.org/obo/GO_0007519	http://purl.obolibrary.org/obo/UPHENO_0050925
+http://purl.obolibrary.org/obo/GO_0030536	http://purl.obolibrary.org/obo/UPHENO_0050253
+http://purl.obolibrary.org/obo/GO_0007517	http://purl.obolibrary.org/obo/UPHENO_0050196
+http://purl.obolibrary.org/obo/GO_0002062	http://purl.obolibrary.org/obo/UPHENO_0050254
+http://purl.obolibrary.org/obo/GO_0014044	http://purl.obolibrary.org/obo/UPHENO_0083069
+http://purl.obolibrary.org/obo/GO_0070314	http://purl.obolibrary.org/obo/UPHENO_0050930
+http://purl.obolibrary.org/obo/GO_1900107	http://purl.obolibrary.org/obo/UPHENO_0050931
+http://purl.obolibrary.org/obo/GO_0060561	http://purl.obolibrary.org/obo/UPHENO_0050933
+http://purl.obolibrary.org/obo/GO_0048696	http://purl.obolibrary.org/obo/UPHENO_0050260
+http://purl.obolibrary.org/obo/GO_0046034	http://purl.obolibrary.org/obo/UPHENO_0050261
+http://purl.obolibrary.org/obo/GO_0030947	http://purl.obolibrary.org/obo/UPHENO_0050262
+http://purl.obolibrary.org/obo/GO_0003341	http://purl.obolibrary.org/obo/UPHENO_0050263
+http://purl.obolibrary.org/obo/GO_0060325	http://purl.obolibrary.org/obo/UPHENO_0050265
+http://purl.obolibrary.org/obo/GO_2000298	http://purl.obolibrary.org/obo/UPHENO_0050266
+http://purl.obolibrary.org/obo/GO_0036486	http://purl.obolibrary.org/obo/UPHENO_0050937
+http://purl.obolibrary.org/obo/GO_0060323	http://purl.obolibrary.org/obo/UPHENO_0050269
+http://purl.obolibrary.org/obo/GO_0060322	http://purl.obolibrary.org/obo/UPHENO_0050153
+http://purl.obolibrary.org/obo/GO_0070365	http://purl.obolibrary.org/obo/UPHENO_0050939
+http://purl.obolibrary.org/obo/GO_0036485	http://purl.obolibrary.org/obo/UPHENO_0050941
+http://purl.obolibrary.org/obo/GO_0070121	http://purl.obolibrary.org/obo/UPHENO_0050270
+http://purl.obolibrary.org/obo/GO_0036484	http://purl.obolibrary.org/obo/UPHENO_0050942
+http://purl.obolibrary.org/obo/GO_0098915	http://purl.obolibrary.org/obo/UPHENO_0083070
+http://purl.obolibrary.org/obo/GO_0071698	http://purl.obolibrary.org/obo/UPHENO_0050944
+http://purl.obolibrary.org/obo/GO_0002244	http://purl.obolibrary.org/obo/UPHENO_0050945
+http://purl.obolibrary.org/obo/GO_0098908	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0060575	http://purl.obolibrary.org/obo/UPHENO_0050950
+http://purl.obolibrary.org/obo/GO_0072554	http://purl.obolibrary.org/obo/UPHENO_0050951
+http://purl.obolibrary.org/obo/GO_0035162	http://purl.obolibrary.org/obo/UPHENO_0050952
+http://purl.obolibrary.org/obo/GO_0006874	http://purl.obolibrary.org/obo/UPHENO_0050278
+http://purl.obolibrary.org/obo/GO_0030968	http://purl.obolibrary.org/obo/UPHENO_0050279
+http://purl.obolibrary.org/obo/GO_0003128	http://purl.obolibrary.org/obo/UPHENO_0050955
+http://purl.obolibrary.org/obo/GO_0006638	http://purl.obolibrary.org/obo/UPHENO_0050956
+http://purl.obolibrary.org/obo/GO_0030728	http://purl.obolibrary.org/obo/UPHENO_0049705
+http://purl.obolibrary.org/obo/GO_0048675	http://purl.obolibrary.org/obo/UPHENO_0050283
+http://purl.obolibrary.org/obo/GO_0045165	http://purl.obolibrary.org/obo/UPHENO_0050282
+http://purl.obolibrary.org/obo/GO_0006631	http://purl.obolibrary.org/obo/UPHENO_0078646
+http://purl.obolibrary.org/obo/GO_0002275	http://purl.obolibrary.org/obo/UPHENO_0050959
+http://purl.obolibrary.org/obo/GO_0035178	http://purl.obolibrary.org/obo/UPHENO_0050962
+http://purl.obolibrary.org/obo/GO_0014016	http://purl.obolibrary.org/obo/UPHENO_0083071
+http://purl.obolibrary.org/obo/GO_0036269	http://purl.obolibrary.org/obo/UPHENO_0050289
+http://purl.obolibrary.org/obo/GO_0036268	http://purl.obolibrary.org/obo/UPHENO_0050290
+http://purl.obolibrary.org/obo/GO_0035176	http://purl.obolibrary.org/obo/UPHENO_0049713
+http://purl.obolibrary.org/obo/GO_0014010	http://purl.obolibrary.org/obo/UPHENO_0050291
+http://purl.obolibrary.org/obo/GO_0036022	http://purl.obolibrary.org/obo/UPHENO_0050964
+http://purl.obolibrary.org/obo/GO_0060307	http://purl.obolibrary.org/obo/UPHENO_0050292
+http://purl.obolibrary.org/obo/GO_0071679	http://purl.obolibrary.org/obo/UPHENO_0050965
+http://purl.obolibrary.org/obo/GO_0002026	http://purl.obolibrary.org/obo/UPHENO_0050294
+http://purl.obolibrary.org/obo/GO_0003357	http://purl.obolibrary.org/obo/UPHENO_0050295
+http://purl.obolibrary.org/obo/GO_0000089	http://purl.obolibrary.org/obo/UPHENO_0083072
+http://purl.obolibrary.org/obo/GO_0003358	http://purl.obolibrary.org/obo/UPHENO_0050296
+http://purl.obolibrary.org/obo/GO_0002027	http://purl.obolibrary.org/obo/UPHENO_0050298
+http://purl.obolibrary.org/obo/GO_0000088	http://purl.obolibrary.org/obo/UPHENO_0083073
+http://purl.obolibrary.org/obo/GO_0048666	http://purl.obolibrary.org/obo/UPHENO_0049719
+http://purl.obolibrary.org/obo/GO_0000084	http://purl.obolibrary.org/obo/UPHENO_0050967
+http://purl.obolibrary.org/obo/GO_0048669	http://purl.obolibrary.org/obo/UPHENO_0050301
+http://purl.obolibrary.org/obo/GO_0048668	http://purl.obolibrary.org/obo/UPHENO_0050304
+http://purl.obolibrary.org/obo/GO_0035188	http://purl.obolibrary.org/obo/UPHENO_0049721
+http://purl.obolibrary.org/obo/GO_0014005	http://purl.obolibrary.org/obo/UPHENO_0050306
+http://purl.obolibrary.org/obo/GO_0060312	http://purl.obolibrary.org/obo/UPHENO_0050308
+http://purl.obolibrary.org/obo/GO_0014003	http://purl.obolibrary.org/obo/UPHENO_0050309
+http://purl.obolibrary.org/obo/GO_0006629	http://purl.obolibrary.org/obo/UPHENO_0049723
+http://purl.obolibrary.org/obo/GO_0061648	http://purl.obolibrary.org/obo/UPHENO_0050310
+http://purl.obolibrary.org/obo/GO_0060319	http://purl.obolibrary.org/obo/UPHENO_0050311
+http://purl.obolibrary.org/obo/GO_0000278	http://purl.obolibrary.org/obo/UPHENO_0050313
+http://purl.obolibrary.org/obo/GO_0030902	http://purl.obolibrary.org/obo/UPHENO_0050314
+http://purl.obolibrary.org/obo/GO_0030901	http://purl.obolibrary.org/obo/UPHENO_0050315
+http://purl.obolibrary.org/obo/GO_0006814	http://purl.obolibrary.org/obo/UPHENO_0050316
+http://purl.obolibrary.org/obo/GO_0030900	http://purl.obolibrary.org/obo/UPHENO_0050317
+http://purl.obolibrary.org/obo/GO_0060363	http://purl.obolibrary.org/obo/UPHENO_0050320
+http://purl.obolibrary.org/obo/GO_0030903	http://purl.obolibrary.org/obo/UPHENO_0050144
+http://purl.obolibrary.org/obo/GO_0060127	http://purl.obolibrary.org/obo/UPHENO_0050976
+http://purl.obolibrary.org/obo/GO_0060126	http://purl.obolibrary.org/obo/UPHENO_0050977
+http://purl.obolibrary.org/obo/GO_0035118	http://purl.obolibrary.org/obo/UPHENO_0050978
+http://purl.obolibrary.org/obo/GO_0060129	http://purl.obolibrary.org/obo/UPHENO_0050979
+http://purl.obolibrary.org/obo/GO_0060128	http://purl.obolibrary.org/obo/UPHENO_0050980
+http://purl.obolibrary.org/obo/GO_0071257	http://purl.obolibrary.org/obo/UPHENO_0050982
+http://purl.obolibrary.org/obo/GO_0003309	http://purl.obolibrary.org/obo/UPHENO_0050322
+http://purl.obolibrary.org/obo/GO_0051899	http://purl.obolibrary.org/obo/UPHENO_0050325
+http://purl.obolibrary.org/obo/GO_0048485	http://purl.obolibrary.org/obo/UPHENO_0050984
+http://purl.obolibrary.org/obo/GO_0072592	http://purl.obolibrary.org/obo/UPHENO_0083074
+http://purl.obolibrary.org/obo/GO_0048484	http://purl.obolibrary.org/obo/UPHENO_0050986
+http://purl.obolibrary.org/obo/GO_0030910	http://purl.obolibrary.org/obo/UPHENO_0050329
+http://purl.obolibrary.org/obo/GO_0072593	http://purl.obolibrary.org/obo/UPHENO_0050987
+http://purl.obolibrary.org/obo/GO_0030917	http://purl.obolibrary.org/obo/UPHENO_0050330
+http://purl.obolibrary.org/obo/GO_0030916	http://purl.obolibrary.org/obo/UPHENO_0050331
+http://purl.obolibrary.org/obo/GO_1901222	http://purl.obolibrary.org/obo/UPHENO_0050332
+http://purl.obolibrary.org/obo/GO_0060132	http://purl.obolibrary.org/obo/UPHENO_0050988
+http://purl.obolibrary.org/obo/GO_0048246	http://purl.obolibrary.org/obo/UPHENO_0050333
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+http://purl.obolibrary.org/obo/GO_0032098	http://purl.obolibrary.org/obo/UPHENO_0050991
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+http://purl.obolibrary.org/obo/GO_1904969	http://purl.obolibrary.org/obo/UPHENO_0050993
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+http://purl.obolibrary.org/obo/GO_0039022	http://purl.obolibrary.org/obo/UPHENO_0051576
+http://purl.obolibrary.org/obo/GO_0055113	http://purl.obolibrary.org/obo/UPHENO_0051577
+http://purl.obolibrary.org/obo/GO_0021501	http://purl.obolibrary.org/obo/UPHENO_0050884
+http://purl.obolibrary.org/obo/GO_0039021	http://purl.obolibrary.org/obo/UPHENO_0051578
+http://purl.obolibrary.org/obo/GO_0039020	http://purl.obolibrary.org/obo/UPHENO_0051579
+http://purl.obolibrary.org/obo/GO_0071600	http://purl.obolibrary.org/obo/UPHENO_0051580
+http://purl.obolibrary.org/obo/GO_0009615	http://purl.obolibrary.org/obo/UPHENO_0051581
diff --git a/src/curation/upheno-fillers/zp/abnormalBiologicalProcessInLocation.tsv b/src/curation/upheno-fillers/zp/abnormalBiologicalProcessInLocation.tsv
new file mode 100644
index 00000000..1ff90430
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormalBiologicalProcessInLocation.tsv
@@ -0,0 +1 @@
+biological_process	location	defined_class
diff --git a/src/curation/upheno-fillers/zp/abnormalCellProliferationInAnatomicalEntity.tsv b/src/curation/upheno-fillers/zp/abnormalCellProliferationInAnatomicalEntity.tsv
new file mode 100644
index 00000000..53687e69
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormalCellProliferationInAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0054392
diff --git a/src/curation/upheno-fillers/zp/abnormalCellularComponent-modified.tsv b/src/curation/upheno-fillers/zp/abnormalCellularComponent-modified.tsv
new file mode 100644
index 00000000..ae66c72d
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormalCellularComponent-modified.tsv
@@ -0,0 +1 @@
+cellular_component	defined_class
diff --git a/src/curation/upheno-fillers/zp/abnormalCoilingOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/zp/abnormalCoilingOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..d7fc165c
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormalCoilingOfAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0078441
diff --git a/src/curation/upheno-fillers/zp/abnormalColorOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/zp/abnormalColorOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..8f1ff7b5
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormalColorOfAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0080210
diff --git a/src/curation/upheno-fillers/zp/abnormalColorOfAnatomicalEntityByColor.tsv b/src/curation/upheno-fillers/zp/abnormalColorOfAnatomicalEntityByColor.tsv
new file mode 100644
index 00000000..bca600b2
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormalColorOfAnatomicalEntityByColor.tsv
@@ -0,0 +1,16 @@
+color	entity	defined_class
+http://purl.obolibrary.org/obo/PATO_0001284	http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0083467
+http://purl.obolibrary.org/obo/PATO_0001251	http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0083468
+http://purl.obolibrary.org/obo/PATO_0000324	http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0083442
+http://purl.obolibrary.org/obo/PATO_0000336	http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0083469
+http://purl.obolibrary.org/obo/PATO_0000952	http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0083470
+http://purl.obolibrary.org/obo/PATO_0001287	http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0083471
+http://purl.obolibrary.org/obo/PATO_0001286	http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0083472
+http://purl.obolibrary.org/obo/PATO_0000320	http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0083462
+http://purl.obolibrary.org/obo/PATO_0001266	http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0083473
+http://purl.obolibrary.org/obo/PATO_0001944	http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0083474
+http://purl.obolibrary.org/obo/PATO_0000317	http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0083475
+http://purl.obolibrary.org/obo/PATO_0000014	http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0083450
+http://purl.obolibrary.org/obo/PATO_0000322	http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0083451
+http://purl.obolibrary.org/obo/PATO_0000323	http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0083452
+http://purl.obolibrary.org/obo/PATO_0000950	http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0083466
diff --git a/src/curation/upheno-fillers/zp/abnormalConstrictionOfAnatomicalEntity-modified.tsv b/src/curation/upheno-fillers/zp/abnormalConstrictionOfAnatomicalEntity-modified.tsv
new file mode 100644
index 00000000..57c76cbb
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormalConstrictionOfAnatomicalEntity-modified.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/zp/abnormalConstrictionOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/zp/abnormalConstrictionOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..e46ae58c
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormalConstrictionOfAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0081834
diff --git a/src/curation/upheno-fillers/zp/abnormalDegenerationOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/zp/abnormalDegenerationOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..44ce495b
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormalDegenerationOfAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0073937
diff --git a/src/curation/upheno-fillers/zp/abnormalDegenerationOfAnatomicalEntityInLocation.tsv b/src/curation/upheno-fillers/zp/abnormalDegenerationOfAnatomicalEntityInLocation.tsv
new file mode 100644
index 00000000..b7121acc
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormalDegenerationOfAnatomicalEntityInLocation.tsv
@@ -0,0 +1 @@
+anatomical_entity	location	defined_class
diff --git a/src/curation/upheno-fillers/zp/abnormalDegenerationOfCellularComponentInLocation.tsv b/src/curation/upheno-fillers/zp/abnormalDegenerationOfCellularComponentInLocation.tsv
new file mode 100644
index 00000000..4b82e9a0
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormalDegenerationOfCellularComponentInLocation.tsv
@@ -0,0 +1 @@
+cellular_component	location	defined_class
diff --git a/src/curation/upheno-fillers/zp/abnormalDistanceBetweenAnatomicalEntities.tsv b/src/curation/upheno-fillers/zp/abnormalDistanceBetweenAnatomicalEntities.tsv
new file mode 100644
index 00000000..23368408
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormalDistanceBetweenAnatomicalEntities.tsv
@@ -0,0 +1,2 @@
+anatomical_entity1	anatomical_entity2	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0012019
diff --git a/src/curation/upheno-fillers/zp/abnormalFunctionalityOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/zp/abnormalFunctionalityOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..32925088
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormalFunctionalityOfAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0002332
diff --git a/src/curation/upheno-fillers/zp/abnormalFunctionalityOfPartOfAnatomicalEntity-modified.tsv b/src/curation/upheno-fillers/zp/abnormalFunctionalityOfPartOfAnatomicalEntity-modified.tsv
new file mode 100644
index 00000000..57c76cbb
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormalFunctionalityOfPartOfAnatomicalEntity-modified.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/zp/abnormalHasFewerPartsOfTypeAnatomicalEntity.tsv b/src/curation/upheno-fillers/zp/abnormalHasFewerPartsOfTypeAnatomicalEntity.tsv
new file mode 100644
index 00000000..64b71c51
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormalHasFewerPartsOfTypeAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+part_anatomical_entity	whole_anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0011318
diff --git a/src/curation/upheno-fillers/zp/abnormalHasFewerPartsOfTypeAnatomicalEntityInLocation.tsv b/src/curation/upheno-fillers/zp/abnormalHasFewerPartsOfTypeAnatomicalEntityInLocation.tsv
new file mode 100644
index 00000000..686251ef
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormalHasFewerPartsOfTypeAnatomicalEntityInLocation.tsv
@@ -0,0 +1 @@
+location	part_anatomical_entity	whole_anatomical_entity	defined_class
diff --git a/src/curation/upheno-fillers/zp/abnormalHeightOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/zp/abnormalHeightOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..c4fa20e8
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormalHeightOfAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0081423
diff --git a/src/curation/upheno-fillers/zp/abnormalLengthOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/zp/abnormalLengthOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..57c76cbb
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormalLengthOfAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/zp/abnormalLevelOfChemicalEntityInLocation.tsv b/src/curation/upheno-fillers/zp/abnormalLevelOfChemicalEntityInLocation.tsv
new file mode 100644
index 00000000..1aad9b8a
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormalLevelOfChemicalEntityInLocation.tsv
@@ -0,0 +1 @@
+chemical_entity	location	defined_class
diff --git a/src/curation/upheno-fillers/zp/abnormalLevelOfChemicalEntityWithRoleInLocation.tsv b/src/curation/upheno-fillers/zp/abnormalLevelOfChemicalEntityWithRoleInLocation.tsv
new file mode 100644
index 00000000..44f878af
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormalLevelOfChemicalEntityWithRoleInLocation.tsv
@@ -0,0 +1 @@
+location	role	defined_class
diff --git a/src/curation/upheno-fillers/zp/abnormalMassDensityOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/zp/abnormalMassDensityOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..c7fa38e4
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormalMassDensityOfAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0084653
diff --git a/src/curation/upheno-fillers/zp/abnormalMobilityOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/zp/abnormalMobilityOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..c6805b06
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormalMobilityOfAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0076943
diff --git a/src/curation/upheno-fillers/zp/abnormalMolecularFunction.tsv b/src/curation/upheno-fillers/zp/abnormalMolecularFunction.tsv
new file mode 100644
index 00000000..50540bbf
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormalMolecularFunction.tsv
@@ -0,0 +1,22 @@
+molecular_function	defined_class
+http://purl.obolibrary.org/obo/GO_0005272	http://purl.obolibrary.org/obo/UPHENO_0031746
+http://purl.obolibrary.org/obo/GO_0008121	http://purl.obolibrary.org/obo/UPHENO_0082998
+http://purl.obolibrary.org/obo/GO_0004364	http://purl.obolibrary.org/obo/UPHENO_0082999
+http://purl.obolibrary.org/obo/GO_0004035	http://purl.obolibrary.org/obo/UPHENO_0031747
+http://purl.obolibrary.org/obo/GO_0008137	http://purl.obolibrary.org/obo/UPHENO_0083000
+http://purl.obolibrary.org/obo/GO_0009008	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0003720	http://purl.obolibrary.org/obo/UPHENO_0031748
+http://purl.obolibrary.org/obo/GO_0005249	http://purl.obolibrary.org/obo/UPHENO_0031750
+http://purl.obolibrary.org/obo/GO_0003674	http://purl.obolibrary.org/obo/UPHENO_0031743
+http://purl.obolibrary.org/obo/GO_0140938	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0017095	http://purl.obolibrary.org/obo/UPHENO_0031751
+http://purl.obolibrary.org/obo/GO_0001588	http://purl.obolibrary.org/obo/UPHENO_0083001
+http://purl.obolibrary.org/obo/GO_0004129	http://purl.obolibrary.org/obo/UPHENO_0031752
+http://purl.obolibrary.org/obo/GO_0055077	http://purl.obolibrary.org/obo/UPHENO_0031753
+http://purl.obolibrary.org/obo/GO_0016772	http://purl.obolibrary.org/obo/UPHENO_0031754
+http://purl.obolibrary.org/obo/GO_0004708	http://purl.obolibrary.org/obo/UPHENO_0031755
+http://purl.obolibrary.org/obo/GO_0140674	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0019799	http://purl.obolibrary.org/obo/UPHENO_0031756
+http://purl.obolibrary.org/obo/GO_0070738	http://purl.obolibrary.org/obo/UPHENO_0031757
+http://purl.obolibrary.org/obo/GO_0009881	http://purl.obolibrary.org/obo/UPHENO_0080363
+http://purl.obolibrary.org/obo/GO_0008086	http://purl.obolibrary.org/obo/UPHENO_0031758
diff --git a/src/curation/upheno-fillers/zp/abnormalMorphologyOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/zp/abnormalMorphologyOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..3e36ee19
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormalMorphologyOfAnatomicalEntity.tsv
@@ -0,0 +1,33 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0020584
diff --git a/src/curation/upheno-fillers/zp/abnormalMorphologyOfAnatomicalEntityInLocation.tsv b/src/curation/upheno-fillers/zp/abnormalMorphologyOfAnatomicalEntityInLocation.tsv
new file mode 100644
index 00000000..b7121acc
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormalMorphologyOfAnatomicalEntityInLocation.tsv
@@ -0,0 +1 @@
+anatomical_entity	location	defined_class
diff --git a/src/curation/upheno-fillers/zp/abnormalMorphologyOfPartOfAnatomicalEntity-modified.tsv b/src/curation/upheno-fillers/zp/abnormalMorphologyOfPartOfAnatomicalEntity-modified.tsv
new file mode 100644
index 00000000..57c76cbb
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormalMorphologyOfPartOfAnatomicalEntity-modified.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/zp/abnormalNumberOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/zp/abnormalNumberOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..cd61b297
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormalNumberOfAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0011498
diff --git a/src/curation/upheno-fillers/zp/abnormalNumberOfAnatomicalEntityInLocation.tsv b/src/curation/upheno-fillers/zp/abnormalNumberOfAnatomicalEntityInLocation.tsv
new file mode 100644
index 00000000..b7121acc
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormalNumberOfAnatomicalEntityInLocation.tsv
@@ -0,0 +1 @@
+anatomical_entity	location	defined_class
diff --git a/src/curation/upheno-fillers/zp/abnormalPigmentationOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/zp/abnormalPigmentationOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..9043ea08
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormalPigmentationOfAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0066794
diff --git a/src/curation/upheno-fillers/zp/abnormalPositionOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/zp/abnormalPositionOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..d6d3ad5c
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormalPositionOfAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0018390
diff --git a/src/curation/upheno-fillers/zp/abnormalPositionOfAnatomicalEntityInLocation.tsv b/src/curation/upheno-fillers/zp/abnormalPositionOfAnatomicalEntityInLocation.tsv
new file mode 100644
index 00000000..b7121acc
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormalPositionOfAnatomicalEntityInLocation.tsv
@@ -0,0 +1 @@
+anatomical_entity	location	defined_class
diff --git a/src/curation/upheno-fillers/zp/abnormalRateOfBiologicalProcess.tsv b/src/curation/upheno-fillers/zp/abnormalRateOfBiologicalProcess.tsv
new file mode 100644
index 00000000..92a3f701
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormalRateOfBiologicalProcess.tsv
@@ -0,0 +1,38 @@
+biological_process	defined_class
+http://purl.obolibrary.org/obo/GO_0032402	http://purl.obolibrary.org/obo/UPHENO_0080384
+http://purl.obolibrary.org/obo/GO_0003401	http://purl.obolibrary.org/obo/UPHENO_0080385
+http://purl.obolibrary.org/obo/GO_0007507	http://purl.obolibrary.org/obo/UPHENO_0080386
+http://purl.obolibrary.org/obo/GO_0006936	http://purl.obolibrary.org/obo/UPHENO_0080387
+http://purl.obolibrary.org/obo/GO_0051402	http://purl.obolibrary.org/obo/UPHENO_0080388
+http://purl.obolibrary.org/obo/GO_1990266	http://purl.obolibrary.org/obo/UPHENO_0080389
+http://purl.obolibrary.org/obo/GO_0051301	http://purl.obolibrary.org/obo/UPHENO_0080390
+http://purl.obolibrary.org/obo/GO_0042074	http://purl.obolibrary.org/obo/UPHENO_0080391
+http://purl.obolibrary.org/obo/GO_0008078	http://purl.obolibrary.org/obo/UPHENO_0080392
+http://purl.obolibrary.org/obo/GO_0009790	http://purl.obolibrary.org/obo/UPHENO_0080393
+http://purl.obolibrary.org/obo/GO_0007049	http://purl.obolibrary.org/obo/UPHENO_0080394
+http://purl.obolibrary.org/obo/GO_0008015	http://purl.obolibrary.org/obo/UPHENO_0080380
+http://purl.obolibrary.org/obo/GO_0061337	http://purl.obolibrary.org/obo/UPHENO_0080395
+http://purl.obolibrary.org/obo/GO_0008283	http://purl.obolibrary.org/obo/UPHENO_0080396
+http://purl.obolibrary.org/obo/GO_0036269	http://purl.obolibrary.org/obo/UPHENO_0080397
+http://purl.obolibrary.org/obo/GO_0060047	http://purl.obolibrary.org/obo/UPHENO_0080398
+http://purl.obolibrary.org/obo/GO_0036268	http://purl.obolibrary.org/obo/UPHENO_0080399
+http://purl.obolibrary.org/obo/GO_0001966	http://purl.obolibrary.org/obo/UPHENO_0080400
+http://purl.obolibrary.org/obo/GO_0033275	http://purl.obolibrary.org/obo/UPHENO_0080401
+http://purl.obolibrary.org/obo/GO_0006915	http://purl.obolibrary.org/obo/UPHENO_0080402
+http://purl.obolibrary.org/obo/GO_0031987	http://purl.obolibrary.org/obo/UPHENO_0080403
+http://purl.obolibrary.org/obo/GO_0048920	http://purl.obolibrary.org/obo/UPHENO_0080404
+http://purl.obolibrary.org/obo/GO_0051876	http://purl.obolibrary.org/obo/UPHENO_0080405
+http://purl.obolibrary.org/obo/GO_0070371	http://purl.obolibrary.org/obo/UPHENO_0080406
+http://purl.obolibrary.org/obo/GO_0031109	http://purl.obolibrary.org/obo/UPHENO_0080407
+http://purl.obolibrary.org/obo/GO_0072592	http://purl.obolibrary.org/obo/UPHENO_0080408
+http://purl.obolibrary.org/obo/GO_0048589	http://purl.obolibrary.org/obo/UPHENO_0080409
+http://purl.obolibrary.org/obo/GO_0006120	http://purl.obolibrary.org/obo/UPHENO_0080410
+http://purl.obolibrary.org/obo/GO_0043133	http://purl.obolibrary.org/obo/UPHENO_0080411
+http://purl.obolibrary.org/obo/GO_1903047	http://purl.obolibrary.org/obo/UPHENO_0080412
+http://purl.obolibrary.org/obo/GO_0007631	http://purl.obolibrary.org/obo/UPHENO_0080413
+http://purl.obolibrary.org/obo/GO_0007596	http://purl.obolibrary.org/obo/UPHENO_0080414
+http://purl.obolibrary.org/obo/GO_0006122	http://purl.obolibrary.org/obo/UPHENO_0080415
+http://purl.obolibrary.org/obo/GO_0046666	http://purl.obolibrary.org/obo/UPHENO_0080416
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UPHENO_0080377
+http://purl.obolibrary.org/obo/GO_0071965	http://purl.obolibrary.org/obo/UPHENO_0080417
+http://purl.obolibrary.org/obo/GO_0031101	http://purl.obolibrary.org/obo/UPHENO_0080418
diff --git a/src/curation/upheno-fillers/zp/abnormalRateOfBiologicalProcessInLocation.tsv b/src/curation/upheno-fillers/zp/abnormalRateOfBiologicalProcessInLocation.tsv
new file mode 100644
index 00000000..1ff90430
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormalRateOfBiologicalProcessInLocation.tsv
@@ -0,0 +1 @@
+biological_process	location	defined_class
diff --git a/src/curation/upheno-fillers/zp/abnormalRateOfContinuousBiologicalProcess.tsv b/src/curation/upheno-fillers/zp/abnormalRateOfContinuousBiologicalProcess.tsv
new file mode 100644
index 00000000..d9616c72
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormalRateOfContinuousBiologicalProcess.tsv
@@ -0,0 +1,3 @@
+biological_process	defined_class
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0060047	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/zp/abnormalShapeOfAnatomicalEntityByShapeType.tsv b/src/curation/upheno-fillers/zp/abnormalShapeOfAnatomicalEntityByShapeType.tsv
new file mode 100644
index 00000000..bd697ba4
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormalShapeOfAnatomicalEntityByShapeType.tsv
@@ -0,0 +1,119 @@
+entity	shape	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0002240	http://purl.obolibrary.org/obo/UPHENO_0041798
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0001200	http://purl.obolibrary.org/obo/UPHENO_0042675
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0001201	http://purl.obolibrary.org/obo/UPHENO_0041555
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0001848	http://purl.obolibrary.org/obo/UPHENO_0041037
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0002252	http://purl.obolibrary.org/obo/UPHENO_0041811
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0002254	http://purl.obolibrary.org/obo/UPHENO_0041041
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0002258	http://purl.obolibrary.org/obo/UPHENO_0041793
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0002031	http://purl.obolibrary.org/obo/UPHENO_0041167
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0005020	http://purl.obolibrary.org/obo/UPHENO_0042048
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0045013	http://purl.obolibrary.org/obo/UPHENO_0083435
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0002008	http://purl.obolibrary.org/obo/UPHENO_0041821
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0001950	http://purl.obolibrary.org/obo/UPHENO_0041048
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0001796	http://purl.obolibrary.org/obo/UPHENO_0041170
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0002007	http://purl.obolibrary.org/obo/UPHENO_0076939
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0001794	http://purl.obolibrary.org/obo/UPHENO_0042199
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0002009	http://purl.obolibrary.org/obo/UPHENO_0041823
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0001154	http://purl.obolibrary.org/obo/UPHENO_0041052
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0002484	http://purl.obolibrary.org/obo/UPHENO_0041832
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0002364	http://purl.obolibrary.org/obo/UPHENO_0041702
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0002400	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0001955	http://purl.obolibrary.org/obo/UPHENO_0041467
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0001798	http://purl.obolibrary.org/obo/UPHENO_0041173
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0002006	http://purl.obolibrary.org/obo/UPHENO_0041838
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0001799	http://purl.obolibrary.org/obo/UPHENO_0041174
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0001466	http://purl.obolibrary.org/obo/UPHENO_0042303
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0001500	http://purl.obolibrary.org/obo/UPHENO_0041571
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0001467	http://purl.obolibrary.org/obo/UPHENO_0042307
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0000410	http://purl.obolibrary.org/obo/UPHENO_0042209
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0000411	http://purl.obolibrary.org/obo/UPHENO_0041181
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0001982	http://purl.obolibrary.org/obo/UPHENO_0042210
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0002154	http://purl.obolibrary.org/obo/UPHENO_0041371
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0001989	http://purl.obolibrary.org/obo/UPHENO_0076940
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0000936	http://purl.obolibrary.org/obo/UPHENO_0041076
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0002034	http://purl.obolibrary.org/obo/UPHENO_0041373
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0000413	http://purl.obolibrary.org/obo/UPHENO_0041189
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0002432	http://purl.obolibrary.org/obo/UPHENO_0041853
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0001468	http://purl.obolibrary.org/obo/UPHENO_0041718
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0000414	http://purl.obolibrary.org/obo/UPHENO_0042212
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0001469	http://purl.obolibrary.org/obo/UPHENO_0041719
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0001865	http://purl.obolibrary.org/obo/UPHENO_0042700
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0002171	http://purl.obolibrary.org/obo/UPHENO_0042425
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0002053	http://purl.obolibrary.org/obo/UPHENO_0041726
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0001481	http://purl.obolibrary.org/obo/UPHENO_0041083
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0001970	http://purl.obolibrary.org/obo/UPHENO_0042220
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0002427	http://purl.obolibrary.org/obo/UPHENO_0041858
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0002143	http://purl.obolibrary.org/obo/UPHENO_0041390
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0000405	http://purl.obolibrary.org/obo/UPHENO_0041200
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0000406	http://purl.obolibrary.org/obo/UPHENO_0041591
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0000407	http://purl.obolibrary.org/obo/UPHENO_0041203
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0002266	http://purl.obolibrary.org/obo/UPHENO_0076941
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0001857	http://purl.obolibrary.org/obo/UPHENO_0041202
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0001979	http://purl.obolibrary.org/obo/UPHENO_0076942
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0000402	http://purl.obolibrary.org/obo/UPHENO_0041204
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0002267	http://purl.obolibrary.org/obo/UPHENO_0041972
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0001977	http://purl.obolibrary.org/obo/UPHENO_0042228
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0000403	http://purl.obolibrary.org/obo/UPHENO_0041205
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0000404	http://purl.obolibrary.org/obo/UPHENO_0041206
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0002281	http://purl.obolibrary.org/obo/UPHENO_0041207
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0001591	http://purl.obolibrary.org/obo/UPHENO_0041098
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0001643	http://purl.obolibrary.org/obo/UPHENO_0042716
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0001368	http://purl.obolibrary.org/obo/UPHENO_0041867
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0002219	http://purl.obolibrary.org/obo/UPHENO_0041868
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0001366	http://purl.obolibrary.org/obo/UPHENO_0041871
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0001883	http://purl.obolibrary.org/obo/UPHENO_0041212
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0001881	http://purl.obolibrary.org/obo/UPHENO_0042717
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0001925	http://purl.obolibrary.org/obo/UPHENO_0042107
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0001409	http://purl.obolibrary.org/obo/UPHENO_0042718
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0002299	http://purl.obolibrary.org/obo/UPHENO_0041981
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0002210	http://purl.obolibrary.org/obo/UPHENO_0041876
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0001649	http://purl.obolibrary.org/obo/UPHENO_0041214
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0001889	http://purl.obolibrary.org/obo/UPHENO_0042722
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0002215	http://purl.obolibrary.org/obo/UPHENO_0041879
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0001873	http://purl.obolibrary.org/obo/UPHENO_0041617
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0001872	http://purl.obolibrary.org/obo/UPHENO_0041620
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0001355	http://purl.obolibrary.org/obo/UPHENO_0041891
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0001594	http://purl.obolibrary.org/obo/UPHENO_0041110
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0001199	http://purl.obolibrary.org/obo/UPHENO_0041995
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0001870	http://purl.obolibrary.org/obo/UPHENO_0042735
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0001592	http://purl.obolibrary.org/obo/UPHENO_0041111
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0001593	http://purl.obolibrary.org/obo/UPHENO_0041113
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0002165	http://purl.obolibrary.org/obo/UPHENO_0041410
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0002286	http://purl.obolibrary.org/obo/UPHENO_0041998
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0000944	http://purl.obolibrary.org/obo/UPHENO_0041114
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0002285	http://purl.obolibrary.org/obo/UPHENO_0041762
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0002164	http://purl.obolibrary.org/obo/UPHENO_0042473
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0000946	http://purl.obolibrary.org/obo/UPHENO_0042627
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0001879	http://purl.obolibrary.org/obo/UPHENO_0041629
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0000947	http://purl.obolibrary.org/obo/UPHENO_0042628
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0002045	http://purl.obolibrary.org/obo/UPHENO_0083436
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0001910	http://purl.obolibrary.org/obo/UPHENO_0041116
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0002169	http://purl.obolibrary.org/obo/UPHENO_0041414
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0001878	http://purl.obolibrary.org/obo/UPHENO_0041630
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0002445	http://purl.obolibrary.org/obo/UPHENO_0041895
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0001359	http://purl.obolibrary.org/obo/UPHENO_0041894
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0002180	http://purl.obolibrary.org/obo/UPHENO_0042140
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0002063	http://purl.obolibrary.org/obo/UPHENO_0041789
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0015019	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0001785	http://purl.obolibrary.org/obo/UPHENO_0041121
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0002239	http://purl.obolibrary.org/obo/UPHENO_0042009
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0001786	http://purl.obolibrary.org/obo/UPHENO_0041122
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0002359	http://purl.obolibrary.org/obo/UPHENO_0041421
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0001784	http://purl.obolibrary.org/obo/UPHENO_0041123
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0000052	http://purl.obolibrary.org/obo/UPHENO_0041226
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0000617	http://purl.obolibrary.org/obo/UPHENO_0041234
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0002232	http://purl.obolibrary.org/obo/UPHENO_0042018
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0001789	http://purl.obolibrary.org/obo/UPHENO_0041127
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0002358	http://purl.obolibrary.org/obo/UPHENO_0042498
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0001787	http://purl.obolibrary.org/obo/UPHENO_0041909
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0001499	http://purl.obolibrary.org/obo/UPHENO_0042509
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0001410	http://purl.obolibrary.org/obo/UPHENO_0041141
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0001495	http://purl.obolibrary.org/obo/UPHENO_0041437
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0001891	http://purl.obolibrary.org/obo/UPHENO_0041342
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0040022	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0001419	http://purl.obolibrary.org/obo/UPHENO_0042361
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0000967	http://purl.obolibrary.org/obo/UPHENO_0041248
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0002065	http://purl.obolibrary.org/obo/UPHENO_0042663
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0001935	http://purl.obolibrary.org/obo/UPHENO_0041783
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0002224	http://purl.obolibrary.org/obo/UPHENO_0042033
diff --git a/src/curation/upheno-fillers/zp/abnormalShapeOfAnatomicalEntityByShapeTypeInLocation.tsv b/src/curation/upheno-fillers/zp/abnormalShapeOfAnatomicalEntityByShapeTypeInLocation.tsv
new file mode 100644
index 00000000..62126e0c
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormalShapeOfAnatomicalEntityByShapeTypeInLocation.tsv
@@ -0,0 +1 @@
+anatomical_entity	location	shape	defined_class
diff --git a/src/curation/upheno-fillers/zp/abnormalShapeOfPhysicalEntity.tsv b/src/curation/upheno-fillers/zp/abnormalShapeOfPhysicalEntity.tsv
new file mode 100644
index 00000000..32373cd2
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormalShapeOfPhysicalEntity.tsv
@@ -0,0 +1,2 @@
+entity	defined_class
+http://purl.obolibrary.org/obo/BFO_0000002	http://purl.obolibrary.org/obo/UPHENO_0080300
diff --git a/src/curation/upheno-fillers/zp/abnormalSizeOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/zp/abnormalSizeOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..c4170116
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormalSizeOfAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0075195
diff --git a/src/curation/upheno-fillers/zp/abnormalSpatialPatternOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/zp/abnormalSpatialPatternOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..f7eca072
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormalSpatialPatternOfAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0080369
diff --git a/src/curation/upheno-fillers/zp/abnormalThicknessOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/zp/abnormalThicknessOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..57c76cbb
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormalThicknessOfAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/zp/abnormallyApoptoticAnatomicalEntity.tsv b/src/curation/upheno-fillers/zp/abnormallyApoptoticAnatomicalEntity.tsv
new file mode 100644
index 00000000..1635b895
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormallyApoptoticAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0076955
diff --git a/src/curation/upheno-fillers/zp/abnormallyApoptoticAnatomicalEntityInLocation.tsv b/src/curation/upheno-fillers/zp/abnormallyApoptoticAnatomicalEntityInLocation.tsv
new file mode 100644
index 00000000..b7121acc
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormallyApoptoticAnatomicalEntityInLocation.tsv
@@ -0,0 +1 @@
+anatomical_entity	location	defined_class
diff --git a/src/curation/upheno-fillers/zp/abnormallyArchedAnatomicalEntity.tsv b/src/curation/upheno-fillers/zp/abnormallyArchedAnatomicalEntity.tsv
new file mode 100644
index 00000000..57c76cbb
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormallyArchedAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/zp/abnormallyArrestedBiologicalProcess.tsv b/src/curation/upheno-fillers/zp/abnormallyArrestedBiologicalProcess.tsv
new file mode 100644
index 00000000..27ade653
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormallyArrestedBiologicalProcess.tsv
@@ -0,0 +1,234 @@
+biological_process	defined_class
+http://purl.obolibrary.org/obo/GO_0033339	http://purl.obolibrary.org/obo/UPHENO_0018923
+http://purl.obolibrary.org/obo/GO_0050976	http://purl.obolibrary.org/obo/UPHENO_0018656
+http://purl.obolibrary.org/obo/GO_0003146	http://purl.obolibrary.org/obo/UPHENO_0018657
+http://purl.obolibrary.org/obo/GO_0006898	http://purl.obolibrary.org/obo/UPHENO_0018658
+http://purl.obolibrary.org/obo/GO_0006897	http://purl.obolibrary.org/obo/UPHENO_0018659
+http://purl.obolibrary.org/obo/GO_0050975	http://purl.obolibrary.org/obo/UPHENO_0018660
+http://purl.obolibrary.org/obo/GO_0001764	http://purl.obolibrary.org/obo/UPHENO_0018924
+http://purl.obolibrary.org/obo/GO_0007626	http://purl.obolibrary.org/obo/UPHENO_0018662
+http://purl.obolibrary.org/obo/GO_0042670	http://purl.obolibrary.org/obo/UPHENO_0018926
+http://purl.obolibrary.org/obo/GO_0003261	http://purl.obolibrary.org/obo/UPHENO_0018668
+http://purl.obolibrary.org/obo/GO_0040011	http://purl.obolibrary.org/obo/UPHENO_0018927
+http://purl.obolibrary.org/obo/GO_0003143	http://purl.obolibrary.org/obo/UPHENO_0018670
+http://purl.obolibrary.org/obo/GO_0040016	http://purl.obolibrary.org/obo/UPHENO_0018931
+http://purl.obolibrary.org/obo/GO_0014037	http://purl.obolibrary.org/obo/UPHENO_0018672
+http://purl.obolibrary.org/obo/GO_0042438	http://purl.obolibrary.org/obo/UPHENO_0018934
+http://purl.obolibrary.org/obo/GO_0030182	http://purl.obolibrary.org/obo/UPHENO_0018932
+http://purl.obolibrary.org/obo/GO_0001889	http://purl.obolibrary.org/obo/UPHENO_0018935
+http://purl.obolibrary.org/obo/GO_0001525	http://purl.obolibrary.org/obo/UPHENO_0018937
+http://purl.obolibrary.org/obo/GO_0030183	http://purl.obolibrary.org/obo/UPHENO_0018938
+http://purl.obolibrary.org/obo/GO_0071896	http://purl.obolibrary.org/obo/UPHENO_0018673
+http://purl.obolibrary.org/obo/GO_0031034	http://purl.obolibrary.org/obo/UPHENO_0018941
+http://purl.obolibrary.org/obo/GO_0048883	http://purl.obolibrary.org/obo/UPHENO_0018679
+http://purl.obolibrary.org/obo/GO_0002040	http://purl.obolibrary.org/obo/UPHENO_0018684
+http://purl.obolibrary.org/obo/GO_0002042	http://purl.obolibrary.org/obo/UPHENO_0018685
+http://purl.obolibrary.org/obo/GO_0014827	http://purl.obolibrary.org/obo/UPHENO_0018948
+http://purl.obolibrary.org/obo/GO_0002041	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0002164	http://purl.obolibrary.org/obo/UPHENO_0018690
+http://purl.obolibrary.org/obo/GO_0044843	http://purl.obolibrary.org/obo/UPHENO_0018951
+http://purl.obolibrary.org/obo/GO_0035881	http://purl.obolibrary.org/obo/UPHENO_0018954
+http://purl.obolibrary.org/obo/GO_0040007	http://purl.obolibrary.org/obo/UPHENO_0018652
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UPHENO_0018635
+http://purl.obolibrary.org/obo/GO_0001756	http://purl.obolibrary.org/obo/UPHENO_0018957
+http://purl.obolibrary.org/obo/GO_0001662	http://purl.obolibrary.org/obo/UPHENO_0018959
+http://purl.obolibrary.org/obo/GO_0001541	http://purl.obolibrary.org/obo/UPHENO_0018960
+http://purl.obolibrary.org/obo/GO_0048752	http://purl.obolibrary.org/obo/UPHENO_0018702
+http://purl.obolibrary.org/obo/GO_0007409	http://purl.obolibrary.org/obo/UPHENO_0018703
+http://purl.obolibrary.org/obo/GO_0007528	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0016477	http://purl.obolibrary.org/obo/UPHENO_0018711
+http://purl.obolibrary.org/obo/GO_0035775	http://purl.obolibrary.org/obo/UPHENO_0018965
+http://purl.obolibrary.org/obo/GO_0042538	http://purl.obolibrary.org/obo/UPHENO_0018966
+http://purl.obolibrary.org/obo/GO_0031290	http://purl.obolibrary.org/obo/UPHENO_0018967
+http://purl.obolibrary.org/obo/GO_0071632	http://purl.obolibrary.org/obo/UPHENO_0018715
+http://purl.obolibrary.org/obo/GO_0031987	http://purl.obolibrary.org/obo/UPHENO_0018716
+http://purl.obolibrary.org/obo/GO_0097352	http://purl.obolibrary.org/obo/UPHENO_0018969
+http://purl.obolibrary.org/obo/GO_0007634	http://purl.obolibrary.org/obo/UPHENO_0018718
+http://purl.obolibrary.org/obo/GO_0007519	http://purl.obolibrary.org/obo/UPHENO_0018720
+http://purl.obolibrary.org/obo/GO_0048066	http://purl.obolibrary.org/obo/UPHENO_0018973
+http://purl.obolibrary.org/obo/GO_0007638	http://purl.obolibrary.org/obo/UPHENO_0018723
+http://purl.obolibrary.org/obo/GO_0007517	http://purl.obolibrary.org/obo/UPHENO_0018724
+http://purl.obolibrary.org/obo/GO_0002062	http://purl.obolibrary.org/obo/UPHENO_0018725
+http://purl.obolibrary.org/obo/GO_0003272	http://purl.obolibrary.org/obo/UPHENO_0018726
+http://purl.obolibrary.org/obo/GO_0006783	http://purl.obolibrary.org/obo/UPHENO_0018728
+http://purl.obolibrary.org/obo/GO_0014044	http://purl.obolibrary.org/obo/UPHENO_0018730
+http://purl.obolibrary.org/obo/GO_0030097	http://purl.obolibrary.org/obo/UPHENO_0018978
+http://purl.obolibrary.org/obo/GO_0001539	http://purl.obolibrary.org/obo/UPHENO_0018980
+http://purl.obolibrary.org/obo/GO_0060879	http://purl.obolibrary.org/obo/UPHENO_0018732
+http://purl.obolibrary.org/obo/GO_0022402	http://purl.obolibrary.org/obo/UPHENO_0018609
+http://purl.obolibrary.org/obo/GO_0002138	http://purl.obolibrary.org/obo/UPHENO_0018735
+http://purl.obolibrary.org/obo/GO_0001843	http://purl.obolibrary.org/obo/UPHENO_0018984
+http://purl.obolibrary.org/obo/GO_0001964	http://purl.obolibrary.org/obo/UPHENO_0018985
+http://purl.obolibrary.org/obo/GO_0007141	http://purl.obolibrary.org/obo/UPHENO_0018987
+http://purl.obolibrary.org/obo/GO_0042110	http://purl.obolibrary.org/obo/UPHENO_0018988
+http://purl.obolibrary.org/obo/GO_0000070	http://purl.obolibrary.org/obo/UPHENO_0018740
+http://purl.obolibrary.org/obo/GO_0042113	http://purl.obolibrary.org/obo/UPHENO_0018992
+http://purl.obolibrary.org/obo/GO_0003341	http://purl.obolibrary.org/obo/UPHENO_0018741
+http://purl.obolibrary.org/obo/GO_0042476	http://purl.obolibrary.org/obo/UPHENO_0018615
+http://purl.obolibrary.org/obo/GO_0036486	http://purl.obolibrary.org/obo/UPHENO_0018747
+http://purl.obolibrary.org/obo/GO_0060322	http://purl.obolibrary.org/obo/UPHENO_0018749
+http://purl.obolibrary.org/obo/GO_0001845	http://purl.obolibrary.org/obo/UPHENO_0019000
+http://purl.obolibrary.org/obo/GO_0001966	http://purl.obolibrary.org/obo/UPHENO_0019001
+http://purl.obolibrary.org/obo/GO_0070121	http://purl.obolibrary.org/obo/UPHENO_0018750
+http://purl.obolibrary.org/obo/GO_0036484	http://purl.obolibrary.org/obo/UPHENO_0018752
+http://purl.obolibrary.org/obo/GO_0071340	http://purl.obolibrary.org/obo/UPHENO_0018753
+http://purl.obolibrary.org/obo/GO_0050882	http://purl.obolibrary.org/obo/UPHENO_0018755
+http://purl.obolibrary.org/obo/GO_0008584	http://purl.obolibrary.org/obo/UPHENO_0019009
+http://purl.obolibrary.org/obo/GO_0008585	http://purl.obolibrary.org/obo/UPHENO_0019010
+http://purl.obolibrary.org/obo/GO_0048565	http://purl.obolibrary.org/obo/UPHENO_0018756
+http://purl.obolibrary.org/obo/GO_0008104	http://purl.obolibrary.org/obo/UPHENO_0019013
+http://purl.obolibrary.org/obo/GO_0042221	http://purl.obolibrary.org/obo/UPHENO_0019014
+http://purl.obolibrary.org/obo/GO_0008347	http://purl.obolibrary.org/obo/UPHENO_0019015
+http://purl.obolibrary.org/obo/GO_0008345	http://purl.obolibrary.org/obo/UPHENO_0019016
+http://purl.obolibrary.org/obo/GO_0060215	http://purl.obolibrary.org/obo/UPHENO_0018759
+http://purl.obolibrary.org/obo/GO_0009798	http://purl.obolibrary.org/obo/UPHENO_0019019
+http://purl.obolibrary.org/obo/GO_0060216	http://purl.obolibrary.org/obo/UPHENO_0018760
+http://purl.obolibrary.org/obo/GO_0090504	http://purl.obolibrary.org/obo/UPHENO_0019022
+http://purl.obolibrary.org/obo/GO_0007140	http://purl.obolibrary.org/obo/UPHENO_0018630
+http://purl.obolibrary.org/obo/GO_0050881	http://purl.obolibrary.org/obo/UPHENO_0018762
+http://purl.obolibrary.org/obo/GO_0060219	http://purl.obolibrary.org/obo/UPHENO_0018765
+http://purl.obolibrary.org/obo/GO_0031017	http://purl.obolibrary.org/obo/UPHENO_0019030
+http://purl.obolibrary.org/obo/GO_0007601	http://purl.obolibrary.org/obo/UPHENO_0018770
+http://purl.obolibrary.org/obo/GO_0003007	http://purl.obolibrary.org/obo/UPHENO_0018771
+http://purl.obolibrary.org/obo/GO_0048798	http://purl.obolibrary.org/obo/UPHENO_0018773
+http://purl.obolibrary.org/obo/GO_0007605	http://purl.obolibrary.org/obo/UPHENO_0018774
+http://purl.obolibrary.org/obo/GO_0003009	http://purl.obolibrary.org/obo/UPHENO_0018775
+http://purl.obolibrary.org/obo/GO_0048797	http://purl.obolibrary.org/obo/UPHENO_0018776
+http://purl.obolibrary.org/obo/GO_0030728	http://purl.obolibrary.org/obo/UPHENO_0079217
+http://purl.obolibrary.org/obo/GO_0042330	http://purl.obolibrary.org/obo/UPHENO_0019032
+http://purl.obolibrary.org/obo/GO_0042331	http://purl.obolibrary.org/obo/UPHENO_0019035
+http://purl.obolibrary.org/obo/GO_0007049	http://purl.obolibrary.org/obo/UPHENO_0018645
+http://purl.obolibrary.org/obo/GO_0008015	http://purl.obolibrary.org/obo/UPHENO_0019038
+http://purl.obolibrary.org/obo/GO_0014812	http://purl.obolibrary.org/obo/UPHENO_0019039
+http://purl.obolibrary.org/obo/GO_0036268	http://purl.obolibrary.org/obo/UPHENO_0018781
+http://purl.obolibrary.org/obo/GO_0001503	http://purl.obolibrary.org/obo/UPHENO_0019045
+http://purl.obolibrary.org/obo/GO_0030282	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0033555	http://purl.obolibrary.org/obo/UPHENO_0019046
+http://purl.obolibrary.org/obo/GO_0035050	http://purl.obolibrary.org/obo/UPHENO_0018785
+http://purl.obolibrary.org/obo/GO_0048785	http://purl.obolibrary.org/obo/UPHENO_0018789
+http://purl.obolibrary.org/obo/GO_0001975	http://purl.obolibrary.org/obo/UPHENO_0019047
+http://purl.obolibrary.org/obo/GO_0007275	http://purl.obolibrary.org/obo/UPHENO_0018643
+http://purl.obolibrary.org/obo/GO_0000084	http://purl.obolibrary.org/obo/UPHENO_0018792
+http://purl.obolibrary.org/obo/GO_0007274	http://purl.obolibrary.org/obo/UPHENO_0019054
+http://purl.obolibrary.org/obo/GO_0003351	http://purl.obolibrary.org/obo/UPHENO_0018793
+http://purl.obolibrary.org/obo/GO_0000080	http://purl.obolibrary.org/obo/UPHENO_0018795
+http://purl.obolibrary.org/obo/GO_0035622	http://purl.obolibrary.org/obo/UPHENO_0019058
+http://purl.obolibrary.org/obo/GO_0035987	http://purl.obolibrary.org/obo/UPHENO_0019060
+http://purl.obolibrary.org/obo/GO_0035188	http://purl.obolibrary.org/obo/UPHENO_0018796
+http://purl.obolibrary.org/obo/GO_0014005	http://purl.obolibrary.org/obo/UPHENO_0018797
+http://purl.obolibrary.org/obo/GO_0007283	http://purl.obolibrary.org/obo/UPHENO_0018631
+http://purl.obolibrary.org/obo/GO_0007281	http://purl.obolibrary.org/obo/UPHENO_0018636
+http://purl.obolibrary.org/obo/GO_0014003	http://purl.obolibrary.org/obo/UPHENO_0018798
+http://purl.obolibrary.org/obo/GO_0032475	http://purl.obolibrary.org/obo/UPHENO_0080553
+http://purl.obolibrary.org/obo/GO_0060319	http://purl.obolibrary.org/obo/UPHENO_0018801
+http://purl.obolibrary.org/obo/GO_0048932	http://purl.obolibrary.org/obo/UPHENO_0019064
+http://purl.obolibrary.org/obo/GO_0000278	http://purl.obolibrary.org/obo/UPHENO_0018804
+http://purl.obolibrary.org/obo/GO_0006936	http://purl.obolibrary.org/obo/UPHENO_0018806
+http://purl.obolibrary.org/obo/GO_0051301	http://purl.obolibrary.org/obo/UPHENO_0018807
+http://purl.obolibrary.org/obo/GO_0006812	http://purl.obolibrary.org/obo/UPHENO_0018808
+http://purl.obolibrary.org/obo/GO_0043482	http://purl.obolibrary.org/obo/UPHENO_0019068
+http://purl.obolibrary.org/obo/GO_0035119	http://purl.obolibrary.org/obo/UPHENO_0018809
+http://purl.obolibrary.org/obo/GO_0046632	http://purl.obolibrary.org/obo/UPHENO_0019070
+http://purl.obolibrary.org/obo/GO_0010996	http://purl.obolibrary.org/obo/UPHENO_0019071
+http://purl.obolibrary.org/obo/GO_0035479	http://purl.obolibrary.org/obo/UPHENO_0018810
+http://purl.obolibrary.org/obo/GO_0061337	http://purl.obolibrary.org/obo/UPHENO_0018811
+http://purl.obolibrary.org/obo/GO_0035116	http://purl.obolibrary.org/obo/UPHENO_0018812
+http://purl.obolibrary.org/obo/GO_0043249	http://purl.obolibrary.org/obo/UPHENO_0019072
+http://purl.obolibrary.org/obo/GO_0035118	http://purl.obolibrary.org/obo/UPHENO_0018814
+http://purl.obolibrary.org/obo/GO_0043009	http://purl.obolibrary.org/obo/UPHENO_0019074
+http://purl.obolibrary.org/obo/GO_0003428	http://purl.obolibrary.org/obo/UPHENO_0018820
+http://purl.obolibrary.org/obo/GO_0021518	http://purl.obolibrary.org/obo/UPHENO_0019078
+http://purl.obolibrary.org/obo/GO_0021999	http://purl.obolibrary.org/obo/UPHENO_0019081
+http://purl.obolibrary.org/obo/GO_0033504	http://purl.obolibrary.org/obo/UPHENO_0019083
+http://purl.obolibrary.org/obo/GO_0030237	http://purl.obolibrary.org/obo/UPHENO_0019085
+http://purl.obolibrary.org/obo/GO_0048920	http://purl.obolibrary.org/obo/UPHENO_0019087
+http://purl.obolibrary.org/obo/GO_0021522	http://purl.obolibrary.org/obo/UPHENO_0019090
+http://purl.obolibrary.org/obo/GO_0030910	http://purl.obolibrary.org/obo/UPHENO_0018828
+http://purl.obolibrary.org/obo/GO_0070293	http://purl.obolibrary.org/obo/UPHENO_0018829
+http://purl.obolibrary.org/obo/GO_0030917	http://purl.obolibrary.org/obo/UPHENO_0018830
+http://purl.obolibrary.org/obo/GO_0045893	http://purl.obolibrary.org/obo/UPHENO_0019094
+http://purl.obolibrary.org/obo/GO_0043473	http://purl.obolibrary.org/obo/UPHENO_0019095
+http://purl.obolibrary.org/obo/GO_0060012	http://purl.obolibrary.org/obo/UPHENO_0018837
+http://purl.obolibrary.org/obo/GO_0071707	http://purl.obolibrary.org/obo/UPHENO_0019105
+http://purl.obolibrary.org/obo/GO_0034394	http://purl.obolibrary.org/obo/UPHENO_0018843
+http://purl.obolibrary.org/obo/GO_0048592	http://purl.obolibrary.org/obo/UPHENO_0018845
+http://purl.obolibrary.org/obo/GO_0007369	http://purl.obolibrary.org/obo/UPHENO_0019108
+http://purl.obolibrary.org/obo/GO_0007127	http://purl.obolibrary.org/obo/UPHENO_0019109
+http://purl.obolibrary.org/obo/GO_0042492	http://purl.obolibrary.org/obo/UPHENO_0019111
+http://purl.obolibrary.org/obo/GO_0071908	http://purl.obolibrary.org/obo/UPHENO_0019112
+http://purl.obolibrary.org/obo/GO_0009790	http://purl.obolibrary.org/obo/UPHENO_0018644
+http://purl.obolibrary.org/obo/GO_0048598	http://purl.obolibrary.org/obo/UPHENO_0018849
+http://purl.obolibrary.org/obo/GO_0043584	http://purl.obolibrary.org/obo/UPHENO_0019115
+http://purl.obolibrary.org/obo/GO_0048477	http://purl.obolibrary.org/obo/UPHENO_0018850
+http://purl.obolibrary.org/obo/GO_0007368	http://purl.obolibrary.org/obo/UPHENO_0019116
+http://purl.obolibrary.org/obo/GO_0060347	http://purl.obolibrary.org/obo/UPHENO_0018856
+http://purl.obolibrary.org/obo/GO_0035138	http://purl.obolibrary.org/obo/UPHENO_0018855
+http://purl.obolibrary.org/obo/GO_0035137	http://purl.obolibrary.org/obo/UPHENO_0018858
+http://purl.obolibrary.org/obo/GO_0035139	http://purl.obolibrary.org/obo/UPHENO_0018859
+http://purl.obolibrary.org/obo/GO_0007492	http://purl.obolibrary.org/obo/UPHENO_0080554
+http://purl.obolibrary.org/obo/GO_0001944	http://purl.obolibrary.org/obo/UPHENO_0019119
+http://purl.obolibrary.org/obo/GO_0001946	http://purl.obolibrary.org/obo/UPHENO_0019120
+http://purl.obolibrary.org/obo/GO_0036342	http://purl.obolibrary.org/obo/UPHENO_0018862
+http://purl.obolibrary.org/obo/GO_0001945	http://purl.obolibrary.org/obo/UPHENO_0019121
+http://purl.obolibrary.org/obo/GO_0001947	http://purl.obolibrary.org/obo/UPHENO_0019122
+http://purl.obolibrary.org/obo/GO_0071599	http://purl.obolibrary.org/obo/UPHENO_0018863
+http://purl.obolibrary.org/obo/GO_0048916	http://purl.obolibrary.org/obo/UPHENO_0019123
+http://purl.obolibrary.org/obo/GO_0051876	http://purl.obolibrary.org/obo/UPHENO_0018868
+http://purl.obolibrary.org/obo/GO_0003317	http://purl.obolibrary.org/obo/UPHENO_0018871
+http://purl.obolibrary.org/obo/GO_0048589	http://purl.obolibrary.org/obo/UPHENO_0018653
+http://purl.obolibrary.org/obo/GO_0010644	http://purl.obolibrary.org/obo/UPHENO_0019129
+http://purl.obolibrary.org/obo/GO_0009416	http://purl.obolibrary.org/obo/UPHENO_0019137
+http://purl.obolibrary.org/obo/GO_0031101	http://purl.obolibrary.org/obo/UPHENO_0019138
+http://purl.obolibrary.org/obo/GO_0060914	http://purl.obolibrary.org/obo/UPHENO_0019139
+http://purl.obolibrary.org/obo/GO_0000236	http://purl.obolibrary.org/obo/UPHENO_0018881
+http://purl.obolibrary.org/obo/GO_0048854	http://purl.obolibrary.org/obo/UPHENO_0019140
+http://purl.obolibrary.org/obo/GO_0000237	http://purl.obolibrary.org/obo/UPHENO_0018882
+http://purl.obolibrary.org/obo/GO_0001568	http://purl.obolibrary.org/obo/UPHENO_0018883
+http://purl.obolibrary.org/obo/GO_0019094	http://purl.obolibrary.org/obo/UPHENO_0018884
+http://purl.obolibrary.org/obo/GO_0034109	http://purl.obolibrary.org/obo/UPHENO_0018885
+http://purl.obolibrary.org/obo/GO_0060840	http://purl.obolibrary.org/obo/UPHENO_0019147
+http://purl.obolibrary.org/obo/GO_0060048	http://purl.obolibrary.org/obo/UPHENO_0018886
+http://purl.obolibrary.org/obo/GO_0060047	http://purl.obolibrary.org/obo/UPHENO_0018888
+http://purl.obolibrary.org/obo/GO_0009605	http://purl.obolibrary.org/obo/UPHENO_0019154
+http://purl.obolibrary.org/obo/GO_0000238	http://purl.obolibrary.org/obo/UPHENO_0018891
+http://purl.obolibrary.org/obo/GO_0003179	http://purl.obolibrary.org/obo/UPHENO_0019156
+http://purl.obolibrary.org/obo/GO_0002089	http://purl.obolibrary.org/obo/UPHENO_0019157
+http://purl.obolibrary.org/obo/GO_0048846	http://purl.obolibrary.org/obo/UPHENO_0019158
+http://purl.obolibrary.org/obo/GO_0001555	http://purl.obolibrary.org/obo/UPHENO_0018893
+http://purl.obolibrary.org/obo/GO_0048840	http://purl.obolibrary.org/obo/UPHENO_0019159
+http://purl.obolibrary.org/obo/GO_0046660	http://purl.obolibrary.org/obo/UPHENO_0079218
+http://purl.obolibrary.org/obo/GO_0030318	http://purl.obolibrary.org/obo/UPHENO_0019160
+http://purl.obolibrary.org/obo/GO_0042060	http://purl.obolibrary.org/obo/UPHENO_0019161
+http://purl.obolibrary.org/obo/GO_0001556	http://purl.obolibrary.org/obo/UPHENO_0018894
+http://purl.obolibrary.org/obo/GO_0003171	http://purl.obolibrary.org/obo/UPHENO_0019163
+http://purl.obolibrary.org/obo/GO_0061386	http://purl.obolibrary.org/obo/UPHENO_0018895
+http://purl.obolibrary.org/obo/GO_0043277	http://purl.obolibrary.org/obo/UPHENO_0019165
+http://purl.obolibrary.org/obo/GO_0002088	http://purl.obolibrary.org/obo/UPHENO_0019169
+http://purl.obolibrary.org/obo/GO_0097095	http://purl.obolibrary.org/obo/UPHENO_0019170
+http://purl.obolibrary.org/obo/GO_0042742	http://purl.obolibrary.org/obo/UPHENO_0018896
+http://purl.obolibrary.org/obo/GO_0030432	http://purl.obolibrary.org/obo/UPHENO_0083062
+http://purl.obolibrary.org/obo/GO_0055007	http://purl.obolibrary.org/obo/UPHENO_0019180
+http://purl.obolibrary.org/obo/GO_0003401	http://purl.obolibrary.org/obo/UPHENO_0018651
+http://purl.obolibrary.org/obo/GO_0032502	http://purl.obolibrary.org/obo/UPHENO_0018610
+http://purl.obolibrary.org/obo/GO_1990169	http://purl.obolibrary.org/obo/UPHENO_0083063
+http://purl.obolibrary.org/obo/GO_0046777	http://purl.obolibrary.org/obo/UPHENO_0019185
+http://purl.obolibrary.org/obo/GO_0045448	http://purl.obolibrary.org/obo/UPHENO_0019189
+http://purl.obolibrary.org/obo/GO_0051321	http://purl.obolibrary.org/obo/UPHENO_0018900
+http://purl.obolibrary.org/obo/GO_0097324	http://purl.obolibrary.org/obo/UPHENO_0018901
+http://purl.obolibrary.org/obo/GO_0033153	http://purl.obolibrary.org/obo/UPHENO_0018904
+http://purl.obolibrary.org/obo/GO_0055002	http://purl.obolibrary.org/obo/UPHENO_0019191
+http://purl.obolibrary.org/obo/GO_0030218	http://purl.obolibrary.org/obo/UPHENO_0019198
+http://purl.obolibrary.org/obo/GO_0030217	http://purl.obolibrary.org/obo/UPHENO_0019199
+http://purl.obolibrary.org/obo/GO_0050908	http://purl.obolibrary.org/obo/UPHENO_0019200
+http://purl.obolibrary.org/obo/GO_0043010	http://purl.obolibrary.org/obo/UPHENO_0019201
+http://purl.obolibrary.org/obo/GO_0003197	http://purl.obolibrary.org/obo/UPHENO_0019206
+http://purl.obolibrary.org/obo/GO_0010842	http://purl.obolibrary.org/obo/UPHENO_0019209
+http://purl.obolibrary.org/obo/GO_0001570	http://purl.obolibrary.org/obo/UPHENO_0018913
+http://purl.obolibrary.org/obo/GO_0060038	http://purl.obolibrary.org/obo/UPHENO_0018914
+http://purl.obolibrary.org/obo/GO_0043931	http://purl.obolibrary.org/obo/UPHENO_0018915
+http://purl.obolibrary.org/obo/GO_0060036	http://purl.obolibrary.org/obo/UPHENO_0018919
+http://purl.obolibrary.org/obo/GO_0048709	http://purl.obolibrary.org/obo/UPHENO_0019214
+http://purl.obolibrary.org/obo/GO_0021508	http://purl.obolibrary.org/obo/UPHENO_0019218
+http://purl.obolibrary.org/obo/GO_0072019	http://purl.obolibrary.org/obo/UPHENO_0018920
+http://purl.obolibrary.org/obo/GO_0055113	http://purl.obolibrary.org/obo/UPHENO_0019221
+http://purl.obolibrary.org/obo/GO_0072017	http://purl.obolibrary.org/obo/UPHENO_0018922
diff --git a/src/curation/upheno-fillers/zp/abnormallyArrestedBiologicalProcessInLocation.tsv b/src/curation/upheno-fillers/zp/abnormallyArrestedBiologicalProcessInLocation.tsv
new file mode 100644
index 00000000..1ff90430
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormallyArrestedBiologicalProcessInLocation.tsv
@@ -0,0 +1 @@
+biological_process	location	defined_class
diff --git a/src/curation/upheno-fillers/zp/abnormallyAsymmetricalAnatomicalEntity.tsv b/src/curation/upheno-fillers/zp/abnormallyAsymmetricalAnatomicalEntity.tsv
new file mode 100644
index 00000000..ba953080
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormallyAsymmetricalAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0084729
diff --git a/src/curation/upheno-fillers/zp/abnormallyBentAnatomicalEntity.tsv b/src/curation/upheno-fillers/zp/abnormallyBentAnatomicalEntity.tsv
new file mode 100644
index 00000000..39b4985e
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormallyBentAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0074399
diff --git a/src/curation/upheno-fillers/zp/abnormallyClosedAnatomicalEntity.tsv b/src/curation/upheno-fillers/zp/abnormallyClosedAnatomicalEntity.tsv
new file mode 100644
index 00000000..dec31fb3
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormallyClosedAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0074228
diff --git a/src/curation/upheno-fillers/zp/abnormallyCurledAnatomicalEntity.tsv b/src/curation/upheno-fillers/zp/abnormallyCurledAnatomicalEntity.tsv
new file mode 100644
index 00000000..57c76cbb
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormallyCurledAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/zp/abnormallyCurvedAnatomicalEntityByOrientation.tsv b/src/curation/upheno-fillers/zp/abnormallyCurvedAnatomicalEntityByOrientation.tsv
new file mode 100644
index 00000000..508022aa
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormallyCurvedAnatomicalEntityByOrientation.tsv
@@ -0,0 +1,16 @@
+anatomical_entity	orientation	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0001848	http://purl.obolibrary.org/obo/UPHENO_0031170
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0001649	http://purl.obolibrary.org/obo/UPHENO_0031253
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0000406	http://purl.obolibrary.org/obo/UPHENO_0031193
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0002031	http://purl.obolibrary.org/obo/UPHENO_0031152
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0001592	http://purl.obolibrary.org/obo/UPHENO_0031268
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0002164	http://purl.obolibrary.org/obo/UPHENO_0031740
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0001593	http://purl.obolibrary.org/obo/UPHENO_0031269
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0002154	http://purl.obolibrary.org/obo/UPHENO_0031294
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0045013	http://purl.obolibrary.org/obo/UPHENO_0084201
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0001785	http://purl.obolibrary.org/obo/UPHENO_0031135
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0001466	http://purl.obolibrary.org/obo/UPHENO_0031453
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0001467	http://purl.obolibrary.org/obo/UPHENO_0031454
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0001789	http://purl.obolibrary.org/obo/UPHENO_0031139
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0001468	http://purl.obolibrary.org/obo/UPHENO_0031363
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0001469	http://purl.obolibrary.org/obo/UPHENO_0031365
diff --git a/src/curation/upheno-fillers/zp/abnormallyDecreasedCoilingOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/zp/abnormallyDecreasedCoilingOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..95729bd7
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormallyDecreasedCoilingOfAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0079498
diff --git a/src/curation/upheno-fillers/zp/abnormallyDecreasedDistanceBetweenAnatomicalEntities.tsv b/src/curation/upheno-fillers/zp/abnormallyDecreasedDistanceBetweenAnatomicalEntities.tsv
new file mode 100644
index 00000000..e35085c1
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormallyDecreasedDistanceBetweenAnatomicalEntities.tsv
@@ -0,0 +1,2 @@
+anatomical_entity1	anatomical_entity2	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0010600
diff --git a/src/curation/upheno-fillers/zp/abnormallyDecreasedFunctionalityOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/zp/abnormallyDecreasedFunctionalityOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..0a7187f9
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormallyDecreasedFunctionalityOfAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0066927
diff --git a/src/curation/upheno-fillers/zp/abnormallyDecreasedFunctionalityOfAnatomicalEntityInLocation.tsv b/src/curation/upheno-fillers/zp/abnormallyDecreasedFunctionalityOfAnatomicalEntityInLocation.tsv
new file mode 100644
index 00000000..54c240cc
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormallyDecreasedFunctionalityOfAnatomicalEntityInLocation.tsv
@@ -0,0 +1,14 @@
+anatomical_entity	entity	defined_class
+http://purl.obolibrary.org/obo/GO_0030424	http://purl.obolibrary.org/obo/BFO_0000004	http://purl.obolibrary.org/obo/UPHENO_0024813
+http://purl.obolibrary.org/obo/GO_0005764	http://purl.obolibrary.org/obo/BFO_0000004	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0005743	http://purl.obolibrary.org/obo/BFO_0000004	http://purl.obolibrary.org/obo/UPHENO_0024874
+http://purl.obolibrary.org/obo/GO_0032421	http://purl.obolibrary.org/obo/BFO_0000004	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0032420	http://purl.obolibrary.org/obo/BFO_0000004	http://purl.obolibrary.org/obo/UPHENO_0024953
+http://purl.obolibrary.org/obo/GO_0005739	http://purl.obolibrary.org/obo/BFO_0000004	http://purl.obolibrary.org/obo/UPHENO_0024904
+http://purl.obolibrary.org/obo/GO_0072686	http://purl.obolibrary.org/obo/BFO_0000004	http://purl.obolibrary.org/obo/UPHENO_0024834
+http://purl.obolibrary.org/obo/GO_0036057	http://purl.obolibrary.org/obo/BFO_0000004	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0005921	http://purl.obolibrary.org/obo/BFO_0000004	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/BFO_0000004	http://purl.obolibrary.org/obo/UPHENO_0024906
+http://purl.obolibrary.org/obo/GO_0005929	http://purl.obolibrary.org/obo/BFO_0000004	http://purl.obolibrary.org/obo/UPHENO_0024857
+http://purl.obolibrary.org/obo/GO_0045335	http://purl.obolibrary.org/obo/BFO_0000004	http://purl.obolibrary.org/obo/UPHENO_0024860
+http://purl.obolibrary.org/obo/GO_0031514	http://purl.obolibrary.org/obo/BFO_0000004	http://purl.obolibrary.org/obo/UPHENO_0024844
diff --git a/src/curation/upheno-fillers/zp/abnormallyDecreasedHeightOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/zp/abnormallyDecreasedHeightOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..4ec56f74
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormallyDecreasedHeightOfAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0080351
diff --git a/src/curation/upheno-fillers/zp/abnormallyDecreasedLengthOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/zp/abnormallyDecreasedLengthOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..c661e30a
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormallyDecreasedLengthOfAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0046505
diff --git a/src/curation/upheno-fillers/zp/abnormallyDecreasedLengthOfAnatomicalEntityInLocation.tsv b/src/curation/upheno-fillers/zp/abnormallyDecreasedLengthOfAnatomicalEntityInLocation.tsv
new file mode 100644
index 00000000..b7121acc
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormallyDecreasedLengthOfAnatomicalEntityInLocation.tsv
@@ -0,0 +1 @@
+anatomical_entity	location	defined_class
diff --git a/src/curation/upheno-fillers/zp/abnormallyDecreasedLevelOfChemicalEntityInLocation.tsv b/src/curation/upheno-fillers/zp/abnormallyDecreasedLevelOfChemicalEntityInLocation.tsv
new file mode 100644
index 00000000..1aad9b8a
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormallyDecreasedLevelOfChemicalEntityInLocation.tsv
@@ -0,0 +1 @@
+chemical_entity	location	defined_class
diff --git a/src/curation/upheno-fillers/zp/abnormallyDecreasedLevelOfChemicalEntityWithRoleInLocation.tsv b/src/curation/upheno-fillers/zp/abnormallyDecreasedLevelOfChemicalEntityWithRoleInLocation.tsv
new file mode 100644
index 00000000..44f878af
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormallyDecreasedLevelOfChemicalEntityWithRoleInLocation.tsv
@@ -0,0 +1 @@
+location	role	defined_class
diff --git a/src/curation/upheno-fillers/zp/abnormallyDecreasedMassDensityOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/zp/abnormallyDecreasedMassDensityOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..0089055a
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormallyDecreasedMassDensityOfAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0082834
diff --git a/src/curation/upheno-fillers/zp/abnormallyDecreasedMassOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/zp/abnormallyDecreasedMassOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..a9eec4ec
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormallyDecreasedMassOfAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0082761
diff --git a/src/curation/upheno-fillers/zp/abnormallyDecreasedMobilityOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/zp/abnormallyDecreasedMobilityOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..ca81007f
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormallyDecreasedMobilityOfAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0076671
diff --git a/src/curation/upheno-fillers/zp/abnormallyDecreasedNumberOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/zp/abnormallyDecreasedNumberOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..c057f89c
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormallyDecreasedNumberOfAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0063722
diff --git a/src/curation/upheno-fillers/zp/abnormallyDecreasedNumberOfAnatomicalEntityInLocation.tsv b/src/curation/upheno-fillers/zp/abnormallyDecreasedNumberOfAnatomicalEntityInLocation.tsv
new file mode 100644
index 00000000..b7121acc
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormallyDecreasedNumberOfAnatomicalEntityInLocation.tsv
@@ -0,0 +1 @@
+anatomical_entity	location	defined_class
diff --git a/src/curation/upheno-fillers/zp/abnormallyDecreasedOccurrenceOfBiologicalProcess.tsv b/src/curation/upheno-fillers/zp/abnormallyDecreasedOccurrenceOfBiologicalProcess.tsv
new file mode 100644
index 00000000..fb10b7ba
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormallyDecreasedOccurrenceOfBiologicalProcess.tsv
@@ -0,0 +1,427 @@
+biological_process	defined_class
+http://purl.obolibrary.org/obo/GO_0003146	http://purl.obolibrary.org/obo/UPHENO_0077436
+http://purl.obolibrary.org/obo/GO_0051701	http://purl.obolibrary.org/obo/UPHENO_0084234
+http://purl.obolibrary.org/obo/GO_1990266	http://purl.obolibrary.org/obo/UPHENO_0077437
+http://purl.obolibrary.org/obo/GO_0007626	http://purl.obolibrary.org/obo/UPHENO_0077431
+http://purl.obolibrary.org/obo/GO_0030866	http://purl.obolibrary.org/obo/UPHENO_0077438
+http://purl.obolibrary.org/obo/GO_0030509	http://purl.obolibrary.org/obo/UPHENO_0077439
+http://purl.obolibrary.org/obo/GO_0003261	http://purl.obolibrary.org/obo/UPHENO_0077441
+http://purl.obolibrary.org/obo/GO_0003140	http://purl.obolibrary.org/obo/UPHENO_0077442
+http://purl.obolibrary.org/obo/GO_0003262	http://purl.obolibrary.org/obo/UPHENO_0077443
+http://purl.obolibrary.org/obo/GO_1902600	http://purl.obolibrary.org/obo/UPHENO_0084235
+http://purl.obolibrary.org/obo/GO_0003144	http://purl.obolibrary.org/obo/UPHENO_0077445
+http://purl.obolibrary.org/obo/GO_0035195	http://purl.obolibrary.org/obo/UPHENO_0077452
+http://purl.obolibrary.org/obo/GO_0018991	http://purl.obolibrary.org/obo/UPHENO_0084236
+http://purl.obolibrary.org/obo/GO_0014032	http://purl.obolibrary.org/obo/UPHENO_0077454
+http://purl.obolibrary.org/obo/GO_0070444	http://purl.obolibrary.org/obo/UPHENO_0077455
+http://purl.obolibrary.org/obo/GO_0007613	http://purl.obolibrary.org/obo/UPHENO_0077456
+http://purl.obolibrary.org/obo/GO_0003014	http://purl.obolibrary.org/obo/UPHENO_0077457
+http://purl.obolibrary.org/obo/GO_0007611	http://purl.obolibrary.org/obo/UPHENO_0077458
+http://purl.obolibrary.org/obo/GO_0007612	http://purl.obolibrary.org/obo/UPHENO_0077459
+http://purl.obolibrary.org/obo/GO_0050962	http://purl.obolibrary.org/obo/UPHENO_0077460
+http://purl.obolibrary.org/obo/GO_0003139	http://purl.obolibrary.org/obo/UPHENO_0077461
+http://purl.obolibrary.org/obo/GO_0002040	http://purl.obolibrary.org/obo/UPHENO_0077464
+http://purl.obolibrary.org/obo/GO_0002281	http://purl.obolibrary.org/obo/UPHENO_0084237
+http://purl.obolibrary.org/obo/GO_0007610	http://purl.obolibrary.org/obo/UPHENO_0077465
+http://purl.obolibrary.org/obo/GO_0002283	http://purl.obolibrary.org/obo/UPHENO_0084238
+http://purl.obolibrary.org/obo/GO_0003011	http://purl.obolibrary.org/obo/UPHENO_0077467
+http://purl.obolibrary.org/obo/GO_0045136	http://purl.obolibrary.org/obo/UPHENO_0084239
+http://purl.obolibrary.org/obo/GO_1900534	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0061502	http://purl.obolibrary.org/obo/UPHENO_0077468
+http://purl.obolibrary.org/obo/GO_0016203	http://purl.obolibrary.org/obo/UPHENO_0077469
+http://purl.obolibrary.org/obo/GO_0061744	http://purl.obolibrary.org/obo/UPHENO_0077470
+http://purl.obolibrary.org/obo/GO_0021923	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0071425	http://purl.obolibrary.org/obo/UPHENO_0077474
+http://purl.obolibrary.org/obo/GO_0051923	http://purl.obolibrary.org/obo/UPHENO_0077475
+http://purl.obolibrary.org/obo/GO_0007529	http://purl.obolibrary.org/obo/UPHENO_0077476
+http://purl.obolibrary.org/obo/GO_0007528	http://purl.obolibrary.org/obo/UPHENO_0077478
+http://purl.obolibrary.org/obo/GO_0003160	http://purl.obolibrary.org/obo/UPHENO_0077479
+http://purl.obolibrary.org/obo/GO_0002194	http://purl.obolibrary.org/obo/UPHENO_0077480
+http://purl.obolibrary.org/obo/GO_0007520	http://purl.obolibrary.org/obo/UPHENO_0077481
+http://purl.obolibrary.org/obo/GO_0070306	http://purl.obolibrary.org/obo/UPHENO_0077483
+http://purl.obolibrary.org/obo/GO_0035095	http://purl.obolibrary.org/obo/UPHENO_0077488
+http://purl.obolibrary.org/obo/GO_0071632	http://purl.obolibrary.org/obo/UPHENO_0077489
+http://purl.obolibrary.org/obo/GO_0007635	http://purl.obolibrary.org/obo/UPHENO_0077490
+http://purl.obolibrary.org/obo/GO_0031987	http://purl.obolibrary.org/obo/UPHENO_0077491
+http://purl.obolibrary.org/obo/GO_0007634	http://purl.obolibrary.org/obo/UPHENO_0077492
+http://purl.obolibrary.org/obo/GO_0007638	http://purl.obolibrary.org/obo/UPHENO_0077495
+http://purl.obolibrary.org/obo/GO_0045475	http://purl.obolibrary.org/obo/UPHENO_0077496
+http://purl.obolibrary.org/obo/GO_0002062	http://purl.obolibrary.org/obo/UPHENO_0077497
+http://purl.obolibrary.org/obo/GO_0003272	http://purl.obolibrary.org/obo/UPHENO_0077499
+http://purl.obolibrary.org/obo/GO_0007631	http://purl.obolibrary.org/obo/UPHENO_0077433
+http://purl.obolibrary.org/obo/GO_0007632	http://purl.obolibrary.org/obo/UPHENO_0077502
+http://purl.obolibrary.org/obo/GO_0021707	http://purl.obolibrary.org/obo/UPHENO_0084241
+http://purl.obolibrary.org/obo/GO_0021828	http://purl.obolibrary.org/obo/UPHENO_0077503
+http://purl.obolibrary.org/obo/GO_0070315	http://purl.obolibrary.org/obo/UPHENO_0077507
+http://purl.obolibrary.org/obo/GO_0021702	http://purl.obolibrary.org/obo/UPHENO_0084242
+http://purl.obolibrary.org/obo/GO_0015012	http://purl.obolibrary.org/obo/UPHENO_0077508
+http://purl.obolibrary.org/obo/GO_0003345	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0003342	http://purl.obolibrary.org/obo/UPHENO_0077514
+http://purl.obolibrary.org/obo/GO_0071333	http://purl.obolibrary.org/obo/UPHENO_0082840
+http://purl.obolibrary.org/obo/GO_0050650	http://purl.obolibrary.org/obo/UPHENO_0077518
+http://purl.obolibrary.org/obo/GO_0071696	http://purl.obolibrary.org/obo/UPHENO_0077519
+http://purl.obolibrary.org/obo/GO_0071698	http://purl.obolibrary.org/obo/UPHENO_0077522
+http://purl.obolibrary.org/obo/GO_0002244	http://purl.obolibrary.org/obo/UPHENO_0077523
+http://purl.obolibrary.org/obo/GO_0045292	http://purl.obolibrary.org/obo/UPHENO_0077524
+http://purl.obolibrary.org/obo/GO_0050768	http://purl.obolibrary.org/obo/UPHENO_0077525
+http://purl.obolibrary.org/obo/GO_0071340	http://purl.obolibrary.org/obo/UPHENO_0077527
+http://purl.obolibrary.org/obo/GO_0002247	http://purl.obolibrary.org/obo/UPHENO_0082841
+http://purl.obolibrary.org/obo/GO_0050883	http://purl.obolibrary.org/obo/UPHENO_0077528
+http://purl.obolibrary.org/obo/GO_0031929	http://purl.obolibrary.org/obo/UPHENO_0077529
+http://purl.obolibrary.org/obo/GO_0045299	http://purl.obolibrary.org/obo/UPHENO_0077532
+http://purl.obolibrary.org/obo/GO_0048565	http://purl.obolibrary.org/obo/UPHENO_0077533
+http://purl.obolibrary.org/obo/GO_0060215	http://purl.obolibrary.org/obo/UPHENO_0077538
+http://purl.obolibrary.org/obo/GO_0060214	http://purl.obolibrary.org/obo/UPHENO_0077539
+http://purl.obolibrary.org/obo/GO_0060216	http://purl.obolibrary.org/obo/UPHENO_0077540
+http://purl.obolibrary.org/obo/GO_0072554	http://purl.obolibrary.org/obo/UPHENO_0077543
+http://purl.obolibrary.org/obo/GO_0050881	http://purl.obolibrary.org/obo/UPHENO_0077544
+http://purl.obolibrary.org/obo/GO_0060219	http://purl.obolibrary.org/obo/UPHENO_0077550
+http://purl.obolibrary.org/obo/GO_0060218	http://purl.obolibrary.org/obo/UPHENO_0077552
+http://purl.obolibrary.org/obo/GO_0072678	http://purl.obolibrary.org/obo/UPHENO_0077554
+http://purl.obolibrary.org/obo/GO_0006635	http://purl.obolibrary.org/obo/UPHENO_0082842
+http://purl.obolibrary.org/obo/GO_0007601	http://purl.obolibrary.org/obo/UPHENO_0077557
+http://purl.obolibrary.org/obo/GO_0090090	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0048798	http://purl.obolibrary.org/obo/UPHENO_0077559
+http://purl.obolibrary.org/obo/GO_0007605	http://purl.obolibrary.org/obo/UPHENO_0077560
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+http://purl.obolibrary.org/obo/GO_0030728	http://purl.obolibrary.org/obo/UPHENO_0077563
+http://purl.obolibrary.org/obo/GO_0048675	http://purl.obolibrary.org/obo/UPHENO_0077566
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+http://purl.obolibrary.org/obo/GO_0000090	http://purl.obolibrary.org/obo/UPHENO_0077571
+http://purl.obolibrary.org/obo/GO_0050879	http://purl.obolibrary.org/obo/UPHENO_0082843
+http://purl.obolibrary.org/obo/GO_0038202	http://purl.obolibrary.org/obo/UPHENO_0077573
+http://purl.obolibrary.org/obo/GO_0019827	http://purl.obolibrary.org/obo/UPHENO_0077574
+http://purl.obolibrary.org/obo/GO_0036269	http://purl.obolibrary.org/obo/UPHENO_0077432
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+http://purl.obolibrary.org/obo/GO_0070586	http://purl.obolibrary.org/obo/UPHENO_0077576
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+http://purl.obolibrary.org/obo/GO_0070588	http://purl.obolibrary.org/obo/UPHENO_0084243
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+http://purl.obolibrary.org/obo/GO_0030851	http://purl.obolibrary.org/obo/UPHENO_0077582
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+http://purl.obolibrary.org/obo/GO_0048668	http://purl.obolibrary.org/obo/UPHENO_0077588
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+http://purl.obolibrary.org/obo/GO_0014005	http://purl.obolibrary.org/obo/UPHENO_0077594
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+http://purl.obolibrary.org/obo/GO_0036158	http://purl.obolibrary.org/obo/UPHENO_0077598
+http://purl.obolibrary.org/obo/GO_0070231	http://purl.obolibrary.org/obo/UPHENO_0077599
+http://purl.obolibrary.org/obo/GO_0060318	http://purl.obolibrary.org/obo/UPHENO_0077600
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+http://purl.obolibrary.org/obo/GO_0060319	http://purl.obolibrary.org/obo/UPHENO_0077603
+http://purl.obolibrary.org/obo/GO_0002574	http://purl.obolibrary.org/obo/UPHENO_0077605
+http://purl.obolibrary.org/obo/GO_0000278	http://purl.obolibrary.org/obo/UPHENO_0077606
+http://purl.obolibrary.org/obo/GO_0006936	http://purl.obolibrary.org/obo/UPHENO_0077608
+http://purl.obolibrary.org/obo/GO_0000398	http://purl.obolibrary.org/obo/UPHENO_0077609
+http://purl.obolibrary.org/obo/GO_0051301	http://purl.obolibrary.org/obo/UPHENO_0077434
+http://purl.obolibrary.org/obo/GO_0006812	http://purl.obolibrary.org/obo/UPHENO_0077610
+http://purl.obolibrary.org/obo/GO_0035479	http://purl.obolibrary.org/obo/UPHENO_0082844
+http://purl.obolibrary.org/obo/GO_0016973	http://purl.obolibrary.org/obo/UPHENO_0077616
+http://purl.obolibrary.org/obo/GO_0060005	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0098719	http://purl.obolibrary.org/obo/UPHENO_0077619
+http://purl.obolibrary.org/obo/GO_0060004	http://purl.obolibrary.org/obo/UPHENO_0077620
+http://purl.obolibrary.org/obo/GO_0036444	http://purl.obolibrary.org/obo/UPHENO_0082845
+http://purl.obolibrary.org/obo/GO_0003309	http://purl.obolibrary.org/obo/UPHENO_0077622
+http://purl.obolibrary.org/obo/GO_0033059	http://purl.obolibrary.org/obo/UPHENO_0077627
+http://purl.obolibrary.org/obo/GO_0002320	http://purl.obolibrary.org/obo/UPHENO_0077631
+http://purl.obolibrary.org/obo/GO_1903409	http://purl.obolibrary.org/obo/UPHENO_0077632
+http://purl.obolibrary.org/obo/GO_0048484	http://purl.obolibrary.org/obo/UPHENO_0077638
+http://purl.obolibrary.org/obo/GO_0048246	http://purl.obolibrary.org/obo/UPHENO_0077641
+http://purl.obolibrary.org/obo/GO_0060134	http://purl.obolibrary.org/obo/UPHENO_0077644
+http://purl.obolibrary.org/obo/GO_0072112	http://purl.obolibrary.org/obo/UPHENO_0077646
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diff --git a/src/curation/upheno-fillers/zp/abnormallyDecreasedOccurrenceOfBiologicalProcessInLocation.tsv b/src/curation/upheno-fillers/zp/abnormallyDecreasedOccurrenceOfBiologicalProcessInLocation.tsv
new file mode 100644
index 00000000..1ff90430
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormallyDecreasedOccurrenceOfBiologicalProcessInLocation.tsv
@@ -0,0 +1 @@
+biological_process	location	defined_class
diff --git a/src/curation/upheno-fillers/zp/abnormallyDecreasedPigmentationOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/zp/abnormallyDecreasedPigmentationOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..546f08b6
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormallyDecreasedPigmentationOfAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0018526
diff --git a/src/curation/upheno-fillers/zp/abnormallyDecreasedPositionOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/zp/abnormallyDecreasedPositionOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..9365f3fc
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormallyDecreasedPositionOfAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0081783
diff --git a/src/curation/upheno-fillers/zp/abnormallyDecreasedQualityOfBiologicalProcess.tsv b/src/curation/upheno-fillers/zp/abnormallyDecreasedQualityOfBiologicalProcess.tsv
new file mode 100644
index 00000000..b242d8e5
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormallyDecreasedQualityOfBiologicalProcess.tsv
@@ -0,0 +1,612 @@
+biological_process	defined_class
+http://purl.obolibrary.org/obo/GO_0048899	http://purl.obolibrary.org/obo/UPHENO_0052182
+http://purl.obolibrary.org/obo/GO_0003146	http://purl.obolibrary.org/obo/UPHENO_0052183
+http://purl.obolibrary.org/obo/GO_0006897	http://purl.obolibrary.org/obo/UPHENO_0052184
+http://purl.obolibrary.org/obo/GO_0050975	http://purl.obolibrary.org/obo/UPHENO_0052185
+http://purl.obolibrary.org/obo/GO_0006412	http://purl.obolibrary.org/obo/UPHENO_0052187
+http://purl.obolibrary.org/obo/GO_0050973	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0007507	http://purl.obolibrary.org/obo/UPHENO_0052188
+http://purl.obolibrary.org/obo/GO_0048894	http://purl.obolibrary.org/obo/UPHENO_0052189
+http://purl.obolibrary.org/obo/GO_0007508	http://purl.obolibrary.org/obo/UPHENO_0052190
+http://purl.obolibrary.org/obo/GO_1990266	http://purl.obolibrary.org/obo/UPHENO_0052191
+http://purl.obolibrary.org/obo/GO_0007626	http://purl.obolibrary.org/obo/UPHENO_0052823
+http://purl.obolibrary.org/obo/GO_0048896	http://purl.obolibrary.org/obo/UPHENO_0052193
+http://purl.obolibrary.org/obo/GO_0030509	http://purl.obolibrary.org/obo/UPHENO_0052196
+http://purl.obolibrary.org/obo/GO_0003260	http://purl.obolibrary.org/obo/UPHENO_0052826
+http://purl.obolibrary.org/obo/GO_0003261	http://purl.obolibrary.org/obo/UPHENO_0052827
+http://purl.obolibrary.org/obo/GO_0003140	http://purl.obolibrary.org/obo/UPHENO_0052198
+http://purl.obolibrary.org/obo/GO_0003262	http://purl.obolibrary.org/obo/UPHENO_0052829
+http://purl.obolibrary.org/obo/GO_0048538	http://purl.obolibrary.org/obo/UPHENO_0052830
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+http://purl.obolibrary.org/obo/GO_0019722	http://purl.obolibrary.org/obo/UPHENO_0052203
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+http://purl.obolibrary.org/obo/GO_0006888	http://purl.obolibrary.org/obo/UPHENO_0052208
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+http://purl.obolibrary.org/obo/GO_0050962	http://purl.obolibrary.org/obo/UPHENO_0052211
+http://purl.obolibrary.org/obo/GO_0045494	http://purl.obolibrary.org/obo/UPHENO_0052850
+http://purl.obolibrary.org/obo/GO_0030878	http://purl.obolibrary.org/obo/UPHENO_0052852
+http://purl.obolibrary.org/obo/GO_0048885	http://purl.obolibrary.org/obo/UPHENO_0052214
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diff --git a/src/curation/upheno-fillers/zp/abnormallyDecreasedQualityOfBiologicalProcessInLocation.tsv b/src/curation/upheno-fillers/zp/abnormallyDecreasedQualityOfBiologicalProcessInLocation.tsv
new file mode 100644
index 00000000..1ff90430
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormallyDecreasedQualityOfBiologicalProcessInLocation.tsv
@@ -0,0 +1 @@
+biological_process	location	defined_class
diff --git a/src/curation/upheno-fillers/zp/abnormallyDecreasedRateOfBiologicalProcess.tsv b/src/curation/upheno-fillers/zp/abnormallyDecreasedRateOfBiologicalProcess.tsv
new file mode 100644
index 00000000..944f4508
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormallyDecreasedRateOfBiologicalProcess.tsv
@@ -0,0 +1,116 @@
+biological_process	defined_class
+http://purl.obolibrary.org/obo/GO_0006777	http://purl.obolibrary.org/obo/UPHENO_0005676
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+http://purl.obolibrary.org/obo/GO_1990266	http://purl.obolibrary.org/obo/UPHENO_0084757
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+http://purl.obolibrary.org/obo/GO_0007586	http://purl.obolibrary.org/obo/UPHENO_0005857
+http://purl.obolibrary.org/obo/GO_0061337	http://purl.obolibrary.org/obo/UPHENO_0005858
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+http://purl.obolibrary.org/obo/GO_0043056	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0007632	http://purl.obolibrary.org/obo/UPHENO_0005734
+http://purl.obolibrary.org/obo/GO_0007596	http://purl.obolibrary.org/obo/UPHENO_0005907
+http://purl.obolibrary.org/obo/GO_0120054	http://purl.obolibrary.org/obo/UPHENO_0080292
+http://purl.obolibrary.org/obo/GO_0061323	http://purl.obolibrary.org/obo/UPHENO_0005911
+http://purl.obolibrary.org/obo/GO_0001539	http://purl.obolibrary.org/obo/UPHENO_0005483
+http://purl.obolibrary.org/obo/GO_0001935	http://purl.obolibrary.org/obo/UPHENO_0005913
+http://purl.obolibrary.org/obo/GO_0072574	http://purl.obolibrary.org/obo/UPHENO_0005914
+http://purl.obolibrary.org/obo/GO_0035264	http://purl.obolibrary.org/obo/UPHENO_0005915
+http://purl.obolibrary.org/obo/GO_0031101	http://purl.obolibrary.org/obo/UPHENO_0005918
+http://purl.obolibrary.org/obo/GO_0043161	http://purl.obolibrary.org/obo/UPHENO_0005920
+http://purl.obolibrary.org/obo/GO_0042074	http://purl.obolibrary.org/obo/UPHENO_0005921
+http://purl.obolibrary.org/obo/GO_0008078	http://purl.obolibrary.org/obo/UPHENO_0005922
+http://purl.obolibrary.org/obo/GO_0009566	http://purl.obolibrary.org/obo/UPHENO_0005496
+http://purl.obolibrary.org/obo/GO_0015840	http://purl.obolibrary.org/obo/UPHENO_0005926
+http://purl.obolibrary.org/obo/GO_1905517	http://purl.obolibrary.org/obo/UPHENO_0005927
+http://purl.obolibrary.org/obo/GO_0006183	http://purl.obolibrary.org/obo/UPHENO_0005763
+http://purl.obolibrary.org/obo/GO_0060048	http://purl.obolibrary.org/obo/UPHENO_0005930
+http://purl.obolibrary.org/obo/GO_0046959	http://purl.obolibrary.org/obo/UPHENO_0080293
+http://purl.obolibrary.org/obo/GO_0060047	http://purl.obolibrary.org/obo/UPHENO_0005931
+http://purl.obolibrary.org/obo/GO_0010272	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0001966	http://purl.obolibrary.org/obo/UPHENO_0005766
+http://purl.obolibrary.org/obo/GO_0022008	http://purl.obolibrary.org/obo/UPHENO_0005933
+http://purl.obolibrary.org/obo/GO_0097497	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0050883	http://purl.obolibrary.org/obo/UPHENO_0005774
+http://purl.obolibrary.org/obo/GO_0050882	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0008584	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0008343	http://purl.obolibrary.org/obo/UPHENO_0082949
+http://purl.obolibrary.org/obo/GO_0008585	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0046785	http://purl.obolibrary.org/obo/UPHENO_0005937
+http://purl.obolibrary.org/obo/GO_0048568	http://purl.obolibrary.org/obo/UPHENO_0005780
+http://purl.obolibrary.org/obo/GO_0008345	http://purl.obolibrary.org/obo/UPHENO_0005781
+http://purl.obolibrary.org/obo/GO_0042742	http://purl.obolibrary.org/obo/UPHENO_0076906
+http://purl.obolibrary.org/obo/GO_0060973	http://purl.obolibrary.org/obo/UPHENO_0005941
+http://purl.obolibrary.org/obo/GO_0090504	http://purl.obolibrary.org/obo/UPHENO_0005785
+http://purl.obolibrary.org/obo/GO_0006171	http://purl.obolibrary.org/obo/UPHENO_0005786
+http://purl.obolibrary.org/obo/GO_0061026	http://purl.obolibrary.org/obo/UPHENO_0076907
+http://purl.obolibrary.org/obo/GO_0050881	http://purl.obolibrary.org/obo/UPHENO_0005507
+http://purl.obolibrary.org/obo/GO_0001957	http://purl.obolibrary.org/obo/UPHENO_0005789
+http://purl.obolibrary.org/obo/GO_0035282	http://purl.obolibrary.org/obo/UPHENO_0005790
+http://purl.obolibrary.org/obo/GO_0006116	http://purl.obolibrary.org/obo/UPHENO_0005946
+http://purl.obolibrary.org/obo/GO_0003401	http://purl.obolibrary.org/obo/UPHENO_0005947
+http://purl.obolibrary.org/obo/GO_0032502	http://purl.obolibrary.org/obo/UPHENO_0005597
+http://purl.obolibrary.org/obo/GO_0099622	http://purl.obolibrary.org/obo/UPHENO_0005948
+http://purl.obolibrary.org/obo/GO_0030449	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0006119	http://purl.obolibrary.org/obo/UPHENO_0005949
+http://purl.obolibrary.org/obo/GO_0030728	http://purl.obolibrary.org/obo/UPHENO_0005519
+http://purl.obolibrary.org/obo/GO_0048794	http://purl.obolibrary.org/obo/UPHENO_0005803
+http://purl.obolibrary.org/obo/GO_0007049	http://purl.obolibrary.org/obo/UPHENO_0005667
+http://purl.obolibrary.org/obo/GO_0043542	http://purl.obolibrary.org/obo/UPHENO_0082950
+http://purl.obolibrary.org/obo/GO_0086009	http://purl.obolibrary.org/obo/UPHENO_0005809
+http://purl.obolibrary.org/obo/GO_0008015	http://purl.obolibrary.org/obo/UPHENO_0005811
+http://purl.obolibrary.org/obo/GO_0070509	http://purl.obolibrary.org/obo/UPHENO_0005957
+http://purl.obolibrary.org/obo/GO_0060026	http://purl.obolibrary.org/obo/UPHENO_0005958
+http://purl.obolibrary.org/obo/GO_0036268	http://purl.obolibrary.org/obo/UPHENO_0005818
+http://purl.obolibrary.org/obo/GO_0072488	http://purl.obolibrary.org/obo/UPHENO_0082951
+http://purl.obolibrary.org/obo/GO_0031099	http://purl.obolibrary.org/obo/UPHENO_0005609
+http://purl.obolibrary.org/obo/GO_0033275	http://purl.obolibrary.org/obo/UPHENO_0005961
+http://purl.obolibrary.org/obo/GO_0033278	http://purl.obolibrary.org/obo/UPHENO_0005962
+http://purl.obolibrary.org/obo/GO_0050900	http://purl.obolibrary.org/obo/UPHENO_0005963
+http://purl.obolibrary.org/obo/GO_0030851	http://purl.obolibrary.org/obo/UPHENO_0005826
+http://purl.obolibrary.org/obo/GO_0060031	http://purl.obolibrary.org/obo/UPHENO_0005968
+http://purl.obolibrary.org/obo/GO_0060030	http://purl.obolibrary.org/obo/UPHENO_0005969
+http://purl.obolibrary.org/obo/GO_0000082	http://purl.obolibrary.org/obo/UPHENO_0005829
+http://purl.obolibrary.org/obo/GO_0003351	http://purl.obolibrary.org/obo/UPHENO_0005831
+http://purl.obolibrary.org/obo/GO_0009060	http://purl.obolibrary.org/obo/UPHENO_0005971
+http://purl.obolibrary.org/obo/GO_0060038	http://purl.obolibrary.org/obo/UPHENO_0005973
+http://purl.obolibrary.org/obo/GO_0034653	http://purl.obolibrary.org/obo/UPHENO_0005836
+http://purl.obolibrary.org/obo/GO_0035188	http://purl.obolibrary.org/obo/UPHENO_0005839
+http://purl.obolibrary.org/obo/GO_0035187	http://purl.obolibrary.org/obo/UPHENO_0005840
+http://purl.obolibrary.org/obo/GO_0015693	http://purl.obolibrary.org/obo/UPHENO_0005843
+http://purl.obolibrary.org/obo/GO_0055113	http://purl.obolibrary.org/obo/UPHENO_0005978
+http://purl.obolibrary.org/obo/GO_0071965	http://purl.obolibrary.org/obo/UPHENO_0005979
+http://purl.obolibrary.org/obo/GO_0031145	http://purl.obolibrary.org/obo/UPHENO_0005844
diff --git a/src/curation/upheno-fillers/zp/abnormallyDecreasedRateOfBiologicalProcessInLocation.tsv b/src/curation/upheno-fillers/zp/abnormallyDecreasedRateOfBiologicalProcessInLocation.tsv
new file mode 100644
index 00000000..1ff90430
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormallyDecreasedRateOfBiologicalProcessInLocation.tsv
@@ -0,0 +1 @@
+biological_process	location	defined_class
diff --git a/src/curation/upheno-fillers/zp/abnormallyDecreasedRateOfContinuousBiologicalProcess.tsv b/src/curation/upheno-fillers/zp/abnormallyDecreasedRateOfContinuousBiologicalProcess.tsv
new file mode 100644
index 00000000..4773013c
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormallyDecreasedRateOfContinuousBiologicalProcess.tsv
@@ -0,0 +1,5 @@
+biological_process	defined_class
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0060047	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0050890	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0008015	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/zp/abnormallyDecreasedRateOfMolecularFunction.tsv b/src/curation/upheno-fillers/zp/abnormallyDecreasedRateOfMolecularFunction.tsv
new file mode 100644
index 00000000..3a9a7bef
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormallyDecreasedRateOfMolecularFunction.tsv
@@ -0,0 +1,5 @@
+molecular_function	defined_class
+http://purl.obolibrary.org/obo/GO_0004683	http://purl.obolibrary.org/obo/UPHENO_0066898
+http://purl.obolibrary.org/obo/GO_0004853	http://purl.obolibrary.org/obo/UPHENO_0066899
+http://purl.obolibrary.org/obo/GO_0003674	http://purl.obolibrary.org/obo/UPHENO_0066865
+http://purl.obolibrary.org/obo/GO_0005248	http://purl.obolibrary.org/obo/UPHENO_0066900
diff --git a/src/curation/upheno-fillers/zp/abnormallyDecreasedSizeOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/zp/abnormallyDecreasedSizeOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..f764e9f0
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormallyDecreasedSizeOfAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0068971
diff --git a/src/curation/upheno-fillers/zp/abnormallyDecreasedSizeOfAnatomicalEntityInLocation.tsv b/src/curation/upheno-fillers/zp/abnormallyDecreasedSizeOfAnatomicalEntityInLocation.tsv
new file mode 100644
index 00000000..b7121acc
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormallyDecreasedSizeOfAnatomicalEntityInLocation.tsv
@@ -0,0 +1 @@
+anatomical_entity	location	defined_class
diff --git a/src/curation/upheno-fillers/zp/abnormallyDecreasedSpeedOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/zp/abnormallyDecreasedSpeedOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..b22947ce
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormallyDecreasedSpeedOfAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0081910
diff --git a/src/curation/upheno-fillers/zp/abnormallyDecreasedStrengthOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/zp/abnormallyDecreasedStrengthOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..53314f60
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormallyDecreasedStrengthOfAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0080555
diff --git a/src/curation/upheno-fillers/zp/abnormallyDecreasedThicknessOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/zp/abnormallyDecreasedThicknessOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..20af83a4
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormallyDecreasedThicknessOfAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0080790
diff --git a/src/curation/upheno-fillers/zp/abnormallyDecreasedTonicityOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/zp/abnormallyDecreasedTonicityOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..ebb9b9f8
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormallyDecreasedTonicityOfAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0082555
diff --git a/src/curation/upheno-fillers/zp/abnormallyDecreasedVolumeOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/zp/abnormallyDecreasedVolumeOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..5a65c101
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormallyDecreasedVolumeOfAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0078429
diff --git a/src/curation/upheno-fillers/zp/abnormallyDecreasedWeightOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/zp/abnormallyDecreasedWeightOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..3234483e
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormallyDecreasedWeightOfAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0054261
diff --git a/src/curation/upheno-fillers/zp/abnormallyDecreasedWidthOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/zp/abnormallyDecreasedWidthOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..f99bd232
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormallyDecreasedWidthOfAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0054567
diff --git a/src/curation/upheno-fillers/zp/abnormallyDecreasedWidthOfAnatomicalEntityInLocation.tsv b/src/curation/upheno-fillers/zp/abnormallyDecreasedWidthOfAnatomicalEntityInLocation.tsv
new file mode 100644
index 00000000..b7121acc
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormallyDecreasedWidthOfAnatomicalEntityInLocation.tsv
@@ -0,0 +1 @@
+anatomical_entity	location	defined_class
diff --git a/src/curation/upheno-fillers/zp/abnormallyDelayedBiologicalProcess.tsv b/src/curation/upheno-fillers/zp/abnormallyDelayedBiologicalProcess.tsv
new file mode 100644
index 00000000..fe3c7a19
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormallyDelayedBiologicalProcess.tsv
@@ -0,0 +1,206 @@
+biological_process	defined_class
+http://purl.obolibrary.org/obo/GO_0033339	http://purl.obolibrary.org/obo/UPHENO_0000745
+http://purl.obolibrary.org/obo/GO_0007623	http://purl.obolibrary.org/obo/UPHENO_0000569
+http://purl.obolibrary.org/obo/GO_0007507	http://purl.obolibrary.org/obo/UPHENO_0000570
+http://purl.obolibrary.org/obo/GO_0051146	http://purl.obolibrary.org/obo/UPHENO_0000747
+http://purl.obolibrary.org/obo/GO_0061053	http://purl.obolibrary.org/obo/UPHENO_0000515
+http://purl.obolibrary.org/obo/GO_0003260	http://purl.obolibrary.org/obo/UPHENO_0000573
+http://purl.obolibrary.org/obo/GO_0042670	http://purl.obolibrary.org/obo/UPHENO_0000748
+http://purl.obolibrary.org/obo/GO_0003261	http://purl.obolibrary.org/obo/UPHENO_0000574
+http://purl.obolibrary.org/obo/GO_0042551	http://purl.obolibrary.org/obo/UPHENO_0000750
+http://purl.obolibrary.org/obo/GO_0048538	http://purl.obolibrary.org/obo/UPHENO_0000576
+http://purl.obolibrary.org/obo/GO_0040016	http://purl.obolibrary.org/obo/UPHENO_0000753
+http://purl.obolibrary.org/obo/GO_0042438	http://purl.obolibrary.org/obo/UPHENO_0000755
+http://purl.obolibrary.org/obo/GO_0030182	http://purl.obolibrary.org/obo/UPHENO_0000754
+http://purl.obolibrary.org/obo/GO_0001889	http://purl.obolibrary.org/obo/UPHENO_0000756
+http://purl.obolibrary.org/obo/GO_0001525	http://purl.obolibrary.org/obo/UPHENO_0000757
+http://purl.obolibrary.org/obo/GO_0001649	http://purl.obolibrary.org/obo/UPHENO_0000759
+http://purl.obolibrary.org/obo/GO_0018991	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0033336	http://purl.obolibrary.org/obo/UPHENO_0000760
+http://purl.obolibrary.org/obo/GO_0048883	http://purl.obolibrary.org/obo/UPHENO_0000584
+http://purl.obolibrary.org/obo/GO_0001755	http://purl.obolibrary.org/obo/UPHENO_0000763
+http://purl.obolibrary.org/obo/GO_0001754	http://purl.obolibrary.org/obo/UPHENO_0000764
+http://purl.obolibrary.org/obo/GO_0048885	http://purl.obolibrary.org/obo/UPHENO_0000585
+http://purl.obolibrary.org/obo/GO_0048644	http://purl.obolibrary.org/obo/UPHENO_0000587
+http://purl.obolibrary.org/obo/GO_0048882	http://purl.obolibrary.org/obo/UPHENO_0000588
+http://purl.obolibrary.org/obo/GO_0002040	http://purl.obolibrary.org/obo/UPHENO_0000589
+http://purl.obolibrary.org/obo/GO_0007296	http://purl.obolibrary.org/obo/UPHENO_0000765
+http://purl.obolibrary.org/obo/GO_0019953	http://purl.obolibrary.org/obo/UPHENO_0083040
+http://purl.obolibrary.org/obo/GO_0040007	http://purl.obolibrary.org/obo/UPHENO_0000541
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UPHENO_0000543
+http://purl.obolibrary.org/obo/GO_0071542	http://purl.obolibrary.org/obo/UPHENO_0000593
+http://purl.obolibrary.org/obo/GO_0001756	http://purl.obolibrary.org/obo/UPHENO_0000769
+http://purl.obolibrary.org/obo/GO_0014020	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0001541	http://purl.obolibrary.org/obo/UPHENO_0000770
+http://purl.obolibrary.org/obo/GO_0048752	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0007528	http://purl.obolibrary.org/obo/UPHENO_0000599
+http://purl.obolibrary.org/obo/GO_0050957	http://purl.obolibrary.org/obo/UPHENO_0000603
+http://purl.obolibrary.org/obo/GO_0048514	http://purl.obolibrary.org/obo/UPHENO_0000604
+http://purl.obolibrary.org/obo/GO_0016477	http://purl.obolibrary.org/obo/UPHENO_0000606
+http://purl.obolibrary.org/obo/GO_0035775	http://purl.obolibrary.org/obo/UPHENO_0000773
+http://purl.obolibrary.org/obo/GO_0031290	http://purl.obolibrary.org/obo/UPHENO_0000775
+http://purl.obolibrary.org/obo/GO_0071872	http://purl.obolibrary.org/obo/UPHENO_0000608
+http://purl.obolibrary.org/obo/GO_1990110	http://purl.obolibrary.org/obo/UPHENO_0083042
+http://purl.obolibrary.org/obo/GO_0001654	http://purl.obolibrary.org/obo/UPHENO_0000777
+http://purl.obolibrary.org/obo/GO_0007519	http://purl.obolibrary.org/obo/UPHENO_0000613
+http://purl.obolibrary.org/obo/GO_0048066	http://purl.obolibrary.org/obo/UPHENO_0000780
+http://purl.obolibrary.org/obo/GO_0045475	http://purl.obolibrary.org/obo/UPHENO_0000615
+http://purl.obolibrary.org/obo/GO_0002062	http://purl.obolibrary.org/obo/UPHENO_0000616
+http://purl.obolibrary.org/obo/GO_0048069	http://purl.obolibrary.org/obo/UPHENO_0000781
+http://purl.obolibrary.org/obo/GO_0060876	http://purl.obolibrary.org/obo/UPHENO_0000619
+http://purl.obolibrary.org/obo/GO_1903232	http://purl.obolibrary.org/obo/UPHENO_0000784
+http://purl.obolibrary.org/obo/GO_0060872	http://purl.obolibrary.org/obo/UPHENO_0000620
+http://purl.obolibrary.org/obo/GO_0030097	http://purl.obolibrary.org/obo/UPHENO_0000787
+http://purl.obolibrary.org/obo/GO_0060879	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0021554	http://purl.obolibrary.org/obo/UPHENO_0000792
+http://purl.obolibrary.org/obo/GO_0001843	http://purl.obolibrary.org/obo/UPHENO_0000794
+http://purl.obolibrary.org/obo/GO_0001964	http://purl.obolibrary.org/obo/UPHENO_0000795
+http://purl.obolibrary.org/obo/GO_0042471	http://purl.obolibrary.org/obo/UPHENO_0000797
+http://purl.obolibrary.org/obo/GO_0048699	http://purl.obolibrary.org/obo/UPHENO_0000624
+http://purl.obolibrary.org/obo/GO_0042472	http://purl.obolibrary.org/obo/UPHENO_0000799
+http://purl.obolibrary.org/obo/GO_0042476	http://purl.obolibrary.org/obo/UPHENO_0000802
+http://purl.obolibrary.org/obo/GO_0034505	http://purl.obolibrary.org/obo/UPHENO_0000803
+http://purl.obolibrary.org/obo/GO_0060322	http://purl.obolibrary.org/obo/UPHENO_0000526
+http://purl.obolibrary.org/obo/GO_0001966	http://purl.obolibrary.org/obo/UPHENO_0000806
+http://purl.obolibrary.org/obo/GO_0036484	http://purl.obolibrary.org/obo/UPHENO_0000630
+http://purl.obolibrary.org/obo/GO_0071698	http://purl.obolibrary.org/obo/UPHENO_0000631
+http://purl.obolibrary.org/obo/GO_0008584	http://purl.obolibrary.org/obo/UPHENO_0000810
+http://purl.obolibrary.org/obo/GO_0008585	http://purl.obolibrary.org/obo/UPHENO_0000811
+http://purl.obolibrary.org/obo/GO_0048565	http://purl.obolibrary.org/obo/UPHENO_0000635
+http://purl.obolibrary.org/obo/GO_0035845	http://purl.obolibrary.org/obo/UPHENO_0000815
+http://purl.obolibrary.org/obo/GO_0048568	http://purl.obolibrary.org/obo/UPHENO_0000637
+http://purl.obolibrary.org/obo/GO_0090504	http://purl.obolibrary.org/obo/UPHENO_0000816
+http://purl.obolibrary.org/obo/GO_0009792	http://purl.obolibrary.org/obo/UPHENO_0000817
+http://purl.obolibrary.org/obo/GO_0035162	http://purl.obolibrary.org/obo/UPHENO_0000641
+http://purl.obolibrary.org/obo/GO_0060219	http://purl.obolibrary.org/obo/UPHENO_0000642
+http://purl.obolibrary.org/obo/GO_0001958	http://purl.obolibrary.org/obo/UPHENO_0000550
+http://purl.obolibrary.org/obo/GO_0001837	http://purl.obolibrary.org/obo/UPHENO_0000819
+http://purl.obolibrary.org/obo/GO_0021575	http://purl.obolibrary.org/obo/UPHENO_0000821
+http://purl.obolibrary.org/obo/GO_0031017	http://purl.obolibrary.org/obo/UPHENO_0000822
+http://purl.obolibrary.org/obo/GO_0031016	http://purl.obolibrary.org/obo/UPHENO_0000823
+http://purl.obolibrary.org/obo/GO_0003006	http://purl.obolibrary.org/obo/UPHENO_0000511
+http://purl.obolibrary.org/obo/GO_0003007	http://purl.obolibrary.org/obo/UPHENO_0000649
+http://purl.obolibrary.org/obo/GO_0048798	http://purl.obolibrary.org/obo/UPHENO_0000650
+http://purl.obolibrary.org/obo/GO_0048797	http://purl.obolibrary.org/obo/UPHENO_0000651
+http://purl.obolibrary.org/obo/GO_0048794	http://purl.obolibrary.org/obo/UPHENO_0000652
+http://purl.obolibrary.org/obo/GO_0048675	http://purl.obolibrary.org/obo/UPHENO_0000653
+http://purl.obolibrary.org/obo/GO_0043542	http://purl.obolibrary.org/obo/UPHENO_0000826
+http://purl.obolibrary.org/obo/GO_0010458	http://purl.obolibrary.org/obo/UPHENO_0000828
+http://purl.obolibrary.org/obo/GO_0008015	http://purl.obolibrary.org/obo/UPHENO_0000829
+http://purl.obolibrary.org/obo/GO_0051726	http://purl.obolibrary.org/obo/UPHENO_0000654
+http://purl.obolibrary.org/obo/GO_0014812	http://purl.obolibrary.org/obo/UPHENO_0000830
+http://purl.obolibrary.org/obo/GO_0001503	http://purl.obolibrary.org/obo/UPHENO_0000527
+http://purl.obolibrary.org/obo/GO_0030282	http://purl.obolibrary.org/obo/UPHENO_0000832
+http://purl.obolibrary.org/obo/GO_0072520	http://purl.obolibrary.org/obo/UPHENO_0076950
+http://purl.obolibrary.org/obo/GO_0035050	http://purl.obolibrary.org/obo/UPHENO_0000659
+http://purl.obolibrary.org/obo/GO_0007275	http://purl.obolibrary.org/obo/UPHENO_0000560
+http://purl.obolibrary.org/obo/GO_0000086	http://purl.obolibrary.org/obo/UPHENO_0000661
+http://purl.obolibrary.org/obo/GO_0048666	http://purl.obolibrary.org/obo/UPHENO_0000662
+http://purl.obolibrary.org/obo/GO_0035188	http://purl.obolibrary.org/obo/UPHENO_0000564
+http://purl.obolibrary.org/obo/GO_0007283	http://purl.obolibrary.org/obo/UPHENO_0000565
+http://purl.obolibrary.org/obo/GO_0055109	http://purl.obolibrary.org/obo/UPHENO_0000839
+http://purl.obolibrary.org/obo/GO_0032402	http://purl.obolibrary.org/obo/UPHENO_0000840
+http://purl.obolibrary.org/obo/GO_0000278	http://purl.obolibrary.org/obo/UPHENO_0000668
+http://purl.obolibrary.org/obo/GO_0030902	http://purl.obolibrary.org/obo/UPHENO_0000669
+http://purl.obolibrary.org/obo/GO_0051301	http://purl.obolibrary.org/obo/UPHENO_0000671
+http://purl.obolibrary.org/obo/GO_1901233	http://purl.obolibrary.org/obo/UPHENO_0076947
+http://purl.obolibrary.org/obo/GO_0030903	http://purl.obolibrary.org/obo/UPHENO_0000672
+http://purl.obolibrary.org/obo/GO_0010996	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0035479	http://purl.obolibrary.org/obo/UPHENO_0000673
+http://purl.obolibrary.org/obo/GO_0043249	http://purl.obolibrary.org/obo/UPHENO_0000843
+http://purl.obolibrary.org/obo/GO_0060005	http://purl.obolibrary.org/obo/UPHENO_0000675
+http://purl.obolibrary.org/obo/GO_0043009	http://purl.obolibrary.org/obo/UPHENO_0000845
+http://purl.obolibrary.org/obo/GO_0061453	http://purl.obolibrary.org/obo/UPHENO_0000677
+http://purl.obolibrary.org/obo/GO_0035476	http://purl.obolibrary.org/obo/UPHENO_0000680
+http://purl.obolibrary.org/obo/GO_0009646	http://purl.obolibrary.org/obo/UPHENO_0083043
+http://purl.obolibrary.org/obo/GO_0048920	http://purl.obolibrary.org/obo/UPHENO_0000850
+http://purl.obolibrary.org/obo/GO_0021885	http://purl.obolibrary.org/obo/UPHENO_0000852
+http://purl.obolibrary.org/obo/GO_0006006	http://purl.obolibrary.org/obo/UPHENO_0080538
+http://purl.obolibrary.org/obo/GO_0030239	http://purl.obolibrary.org/obo/UPHENO_0000854
+http://purl.obolibrary.org/obo/GO_0043473	http://purl.obolibrary.org/obo/UPHENO_0000855
+http://purl.obolibrary.org/obo/GO_0043476	http://purl.obolibrary.org/obo/UPHENO_0000856
+http://purl.obolibrary.org/obo/GO_0060379	http://purl.obolibrary.org/obo/UPHENO_0000684
+http://purl.obolibrary.org/obo/GO_0021529	http://purl.obolibrary.org/obo/UPHENO_0000861
+http://purl.obolibrary.org/obo/GO_0007369	http://purl.obolibrary.org/obo/UPHENO_0000863
+http://purl.obolibrary.org/obo/GO_0003203	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0042491	http://purl.obolibrary.org/obo/UPHENO_0000867
+http://purl.obolibrary.org/obo/GO_0048599	http://purl.obolibrary.org/obo/UPHENO_0000690
+http://purl.obolibrary.org/obo/GO_0009790	http://purl.obolibrary.org/obo/UPHENO_0000869
+http://purl.obolibrary.org/obo/GO_0006950	http://purl.obolibrary.org/obo/UPHENO_0000518
+http://purl.obolibrary.org/obo/GO_0060348	http://purl.obolibrary.org/obo/UPHENO_0000697
+http://purl.obolibrary.org/obo/GO_0060221	http://purl.obolibrary.org/obo/UPHENO_0000698
+http://purl.obolibrary.org/obo/GO_0001702	http://purl.obolibrary.org/obo/UPHENO_0000870
+http://purl.obolibrary.org/obo/GO_1990402	http://purl.obolibrary.org/obo/UPHENO_0080539
+http://purl.obolibrary.org/obo/GO_0036342	http://purl.obolibrary.org/obo/UPHENO_0000700
+http://purl.obolibrary.org/obo/GO_0001945	http://purl.obolibrary.org/obo/UPHENO_0000871
+http://purl.obolibrary.org/obo/GO_0001947	http://purl.obolibrary.org/obo/UPHENO_0000872
+http://purl.obolibrary.org/obo/GO_0071599	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0051877	http://purl.obolibrary.org/obo/UPHENO_0000702
+http://purl.obolibrary.org/obo/GO_0003317	http://purl.obolibrary.org/obo/UPHENO_0000704
+http://purl.obolibrary.org/obo/GO_0060471	http://purl.obolibrary.org/obo/UPHENO_0000706
+http://purl.obolibrary.org/obo/GO_0060350	http://purl.obolibrary.org/obo/UPHENO_0000707
+http://purl.obolibrary.org/obo/GO_0048589	http://purl.obolibrary.org/obo/UPHENO_0000535
+http://purl.obolibrary.org/obo/GO_0007350	http://purl.obolibrary.org/obo/UPHENO_0080540
+http://purl.obolibrary.org/obo/GO_0060351	http://purl.obolibrary.org/obo/UPHENO_0000709
+http://purl.obolibrary.org/obo/GO_0007599	http://purl.obolibrary.org/obo/UPHENO_0000875
+http://purl.obolibrary.org/obo/GO_0007596	http://purl.obolibrary.org/obo/UPHENO_0000876
+http://purl.obolibrary.org/obo/GO_0035701	http://purl.obolibrary.org/obo/UPHENO_0000878
+http://purl.obolibrary.org/obo/GO_0003318	http://purl.obolibrary.org/obo/UPHENO_0000714
+http://purl.obolibrary.org/obo/GO_0009416	http://purl.obolibrary.org/obo/UPHENO_0083044
+http://purl.obolibrary.org/obo/GO_0031101	http://purl.obolibrary.org/obo/UPHENO_0000883
+http://purl.obolibrary.org/obo/GO_0060914	http://purl.obolibrary.org/obo/UPHENO_0000884
+http://purl.obolibrary.org/obo/GO_0001568	http://purl.obolibrary.org/obo/UPHENO_0000715
+http://purl.obolibrary.org/obo/GO_0097421	http://purl.obolibrary.org/obo/UPHENO_0076948
+http://purl.obolibrary.org/obo/GO_0042074	http://purl.obolibrary.org/obo/UPHENO_0000886
+http://purl.obolibrary.org/obo/GO_0008078	http://purl.obolibrary.org/obo/UPHENO_0000716
+http://purl.obolibrary.org/obo/GO_0060042	http://purl.obolibrary.org/obo/UPHENO_0000717
+http://purl.obolibrary.org/obo/GO_0060041	http://purl.obolibrary.org/obo/UPHENO_0000718
+http://purl.obolibrary.org/obo/GO_0050936	http://purl.obolibrary.org/obo/UPHENO_0000893
+http://purl.obolibrary.org/obo/GO_0007420	http://purl.obolibrary.org/obo/UPHENO_0000894
+http://purl.obolibrary.org/obo/GO_0060040	http://purl.obolibrary.org/obo/UPHENO_0000719
+http://purl.obolibrary.org/obo/GO_0003187	http://purl.obolibrary.org/obo/UPHENO_0080541
+http://purl.obolibrary.org/obo/GO_0003188	http://purl.obolibrary.org/obo/UPHENO_0076949
+http://purl.obolibrary.org/obo/GO_0043049	http://purl.obolibrary.org/obo/UPHENO_0000895
+http://purl.obolibrary.org/obo/GO_0060047	http://purl.obolibrary.org/obo/UPHENO_0000722
+http://purl.obolibrary.org/obo/GO_0031076	http://purl.obolibrary.org/obo/UPHENO_0000723
+http://purl.obolibrary.org/obo/GO_0048859	http://purl.obolibrary.org/obo/UPHENO_0000900
+http://purl.obolibrary.org/obo/GO_0022007	http://purl.obolibrary.org/obo/UPHENO_0080542
+http://purl.obolibrary.org/obo/GO_0048844	http://purl.obolibrary.org/obo/UPHENO_0000903
+http://purl.obolibrary.org/obo/GO_0002089	http://purl.obolibrary.org/obo/UPHENO_0000905
+http://purl.obolibrary.org/obo/GO_0051216	http://purl.obolibrary.org/obo/UPHENO_0000726
+http://purl.obolibrary.org/obo/GO_0030318	http://purl.obolibrary.org/obo/UPHENO_0000907
+http://purl.obolibrary.org/obo/GO_0030316	http://purl.obolibrary.org/obo/UPHENO_0000908
+http://purl.obolibrary.org/obo/GO_1902355	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0061386	http://purl.obolibrary.org/obo/UPHENO_0000727
+http://purl.obolibrary.org/obo/GO_0002088	http://purl.obolibrary.org/obo/UPHENO_0000912
+http://purl.obolibrary.org/obo/GO_0061381	http://purl.obolibrary.org/obo/UPHENO_0000728
+http://purl.obolibrary.org/obo/GO_0014866	http://purl.obolibrary.org/obo/UPHENO_0083045
+http://purl.obolibrary.org/obo/GO_0060975	http://purl.obolibrary.org/obo/UPHENO_0000919
+http://purl.obolibrary.org/obo/GO_0060059	http://purl.obolibrary.org/obo/UPHENO_0000729
+http://purl.obolibrary.org/obo/GO_0030431	http://purl.obolibrary.org/obo/UPHENO_0000924
+http://purl.obolibrary.org/obo/GO_0003401	http://purl.obolibrary.org/obo/UPHENO_0080543
+http://purl.obolibrary.org/obo/GO_0032502	http://purl.obolibrary.org/obo/UPHENO_0000508
+http://purl.obolibrary.org/obo/GO_0060028	http://purl.obolibrary.org/obo/UPHENO_0000730
+http://purl.obolibrary.org/obo/GO_0060027	http://purl.obolibrary.org/obo/UPHENO_0000731
+http://purl.obolibrary.org/obo/GO_0036306	http://purl.obolibrary.org/obo/UPHENO_0000732
+http://purl.obolibrary.org/obo/GO_0060026	http://purl.obolibrary.org/obo/UPHENO_0000733
+http://purl.obolibrary.org/obo/GO_0051320	http://purl.obolibrary.org/obo/UPHENO_0000735
+http://purl.obolibrary.org/obo/GO_0003407	http://purl.obolibrary.org/obo/UPHENO_0000736
+http://purl.obolibrary.org/obo/GO_0099625	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0006915	http://purl.obolibrary.org/obo/UPHENO_0000737
+http://purl.obolibrary.org/obo/GO_0008406	http://purl.obolibrary.org/obo/UPHENO_0000929
+http://purl.obolibrary.org/obo/GO_0048823	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0030218	http://purl.obolibrary.org/obo/UPHENO_0000932
+http://purl.obolibrary.org/obo/GO_0030217	http://purl.obolibrary.org/obo/UPHENO_0000934
+http://purl.obolibrary.org/obo/GO_0060030	http://purl.obolibrary.org/obo/UPHENO_0000738
+http://purl.obolibrary.org/obo/GO_0048703	http://purl.obolibrary.org/obo/UPHENO_0000938
+http://purl.obolibrary.org/obo/GO_0010842	http://purl.obolibrary.org/obo/UPHENO_0000939
+http://purl.obolibrary.org/obo/GO_0043931	http://purl.obolibrary.org/obo/UPHENO_0000740
+http://purl.obolibrary.org/obo/GO_0072378	http://purl.obolibrary.org/obo/UPHENO_0000741
+http://purl.obolibrary.org/obo/GO_0055110	http://purl.obolibrary.org/obo/UPHENO_0000943
+http://purl.obolibrary.org/obo/GO_0021505	http://purl.obolibrary.org/obo/UPHENO_0000945
+http://purl.obolibrary.org/obo/GO_0009617	http://purl.obolibrary.org/obo/UPHENO_0000946
+http://purl.obolibrary.org/obo/GO_0021986	http://purl.obolibrary.org/obo/UPHENO_0000947
+http://purl.obolibrary.org/obo/GO_0039022	http://purl.obolibrary.org/obo/UPHENO_0000948
+http://purl.obolibrary.org/obo/GO_0055113	http://purl.obolibrary.org/obo/UPHENO_0000949
+http://purl.obolibrary.org/obo/GO_0006909	http://purl.obolibrary.org/obo/UPHENO_0000744
diff --git a/src/curation/upheno-fillers/zp/abnormallyDelayedBiologicalProcessInLocation.tsv b/src/curation/upheno-fillers/zp/abnormallyDelayedBiologicalProcessInLocation.tsv
new file mode 100644
index 00000000..1ff90430
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormallyDelayedBiologicalProcessInLocation.tsv
@@ -0,0 +1 @@
+biological_process	location	defined_class
diff --git a/src/curation/upheno-fillers/zp/abnormallyDetachedAnatomicalEntities.tsv b/src/curation/upheno-fillers/zp/abnormallyDetachedAnatomicalEntities.tsv
new file mode 100644
index 00000000..2868225a
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormallyDetachedAnatomicalEntities.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	anatomical_entity_detached_from	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0081667
diff --git a/src/curation/upheno-fillers/zp/abnormallyDilatedAnatomicalEntity.tsv b/src/curation/upheno-fillers/zp/abnormallyDilatedAnatomicalEntity.tsv
new file mode 100644
index 00000000..6e1084c2
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormallyDilatedAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0084124
diff --git a/src/curation/upheno-fillers/zp/abnormallyDuplicatedAnatomicalEntity.tsv b/src/curation/upheno-fillers/zp/abnormallyDuplicatedAnatomicalEntity.tsv
new file mode 100644
index 00000000..ce51d6c8
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormallyDuplicatedAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0075340
diff --git a/src/curation/upheno-fillers/zp/abnormallyDuplicatedAnatomicalEntityInLocation.tsv b/src/curation/upheno-fillers/zp/abnormallyDuplicatedAnatomicalEntityInLocation.tsv
new file mode 100644
index 00000000..b7121acc
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormallyDuplicatedAnatomicalEntityInLocation.tsv
@@ -0,0 +1 @@
+anatomical_entity	location	defined_class
diff --git a/src/curation/upheno-fillers/zp/abnormallyEvertedAnatomicalEntity.tsv b/src/curation/upheno-fillers/zp/abnormallyEvertedAnatomicalEntity.tsv
new file mode 100644
index 00000000..29bfb9de
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormallyEvertedAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0080241
diff --git a/src/curation/upheno-fillers/zp/abnormallyFusedAnatomicalEntities.tsv b/src/curation/upheno-fillers/zp/abnormallyFusedAnatomicalEntities.tsv
new file mode 100644
index 00000000..6363a024
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormallyFusedAnatomicalEntities.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	anatomical_entity_fused_with	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0078125
diff --git a/src/curation/upheno-fillers/zp/abnormallyFusedAnatomicalEntitiesInLocation.tsv b/src/curation/upheno-fillers/zp/abnormallyFusedAnatomicalEntitiesInLocation.tsv
new file mode 100644
index 00000000..e0353c20
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormallyFusedAnatomicalEntitiesInLocation.tsv
@@ -0,0 +1 @@
+anatomical_entity	anatomical_entity_fused_with	location	location_fused_with	defined_class
diff --git a/src/curation/upheno-fillers/zp/abnormallyGreasyAnatomicalEntity.tsv b/src/curation/upheno-fillers/zp/abnormallyGreasyAnatomicalEntity.tsv
new file mode 100644
index 00000000..57c76cbb
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormallyGreasyAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/zp/abnormallyImmobileAnatomicalEntity.tsv b/src/curation/upheno-fillers/zp/abnormallyImmobileAnatomicalEntity.tsv
new file mode 100644
index 00000000..b7e27978
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormallyImmobileAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0081417
diff --git a/src/curation/upheno-fillers/zp/abnormallyIncompleteClosureOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/zp/abnormallyIncompleteClosureOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..dc495ee7
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormallyIncompleteClosureOfAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0033572
diff --git a/src/curation/upheno-fillers/zp/abnormallyIncreasedDistanceBetweenAnatomicalEntities.tsv b/src/curation/upheno-fillers/zp/abnormallyIncreasedDistanceBetweenAnatomicalEntities.tsv
new file mode 100644
index 00000000..c3bfcd11
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormallyIncreasedDistanceBetweenAnatomicalEntities.tsv
@@ -0,0 +1,2 @@
+entity1	entity2	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0054477
diff --git a/src/curation/upheno-fillers/zp/abnormallyIncreasedFunctionalityOfAnatomicalEntityInLocation.tsv b/src/curation/upheno-fillers/zp/abnormallyIncreasedFunctionalityOfAnatomicalEntityInLocation.tsv
new file mode 100644
index 00000000..b7121acc
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormallyIncreasedFunctionalityOfAnatomicalEntityInLocation.tsv
@@ -0,0 +1 @@
+anatomical_entity	location	defined_class
diff --git a/src/curation/upheno-fillers/zp/abnormallyIncreasedHeightOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/zp/abnormallyIncreasedHeightOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..b4b43407
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormallyIncreasedHeightOfAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0063513
diff --git a/src/curation/upheno-fillers/zp/abnormallyIncreasedHeightOfAnatomicalEntityInLocation.tsv b/src/curation/upheno-fillers/zp/abnormallyIncreasedHeightOfAnatomicalEntityInLocation.tsv
new file mode 100644
index 00000000..b7121acc
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormallyIncreasedHeightOfAnatomicalEntityInLocation.tsv
@@ -0,0 +1 @@
+anatomical_entity	location	defined_class
diff --git a/src/curation/upheno-fillers/zp/abnormallyIncreasedLengthOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/zp/abnormallyIncreasedLengthOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..b9cad5a7
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormallyIncreasedLengthOfAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0072195
diff --git a/src/curation/upheno-fillers/zp/abnormallyIncreasedLengthOfAnatomicalEntityInLocation.tsv b/src/curation/upheno-fillers/zp/abnormallyIncreasedLengthOfAnatomicalEntityInLocation.tsv
new file mode 100644
index 00000000..b7121acc
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormallyIncreasedLengthOfAnatomicalEntityInLocation.tsv
@@ -0,0 +1 @@
+anatomical_entity	location	defined_class
diff --git a/src/curation/upheno-fillers/zp/abnormallyIncreasedLevelOfChemicalEntityInLocation.tsv b/src/curation/upheno-fillers/zp/abnormallyIncreasedLevelOfChemicalEntityInLocation.tsv
new file mode 100644
index 00000000..1aad9b8a
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormallyIncreasedLevelOfChemicalEntityInLocation.tsv
@@ -0,0 +1 @@
+chemical_entity	location	defined_class
diff --git a/src/curation/upheno-fillers/zp/abnormallyIncreasedLevelOfChemicalEntityWithRoleInLocation.tsv b/src/curation/upheno-fillers/zp/abnormallyIncreasedLevelOfChemicalEntityWithRoleInLocation.tsv
new file mode 100644
index 00000000..44f878af
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormallyIncreasedLevelOfChemicalEntityWithRoleInLocation.tsv
@@ -0,0 +1 @@
+location	role	defined_class
diff --git a/src/curation/upheno-fillers/zp/abnormallyIncreasedMassDensityOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/zp/abnormallyIncreasedMassDensityOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..9b76205d
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormallyIncreasedMassDensityOfAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0084449
diff --git a/src/curation/upheno-fillers/zp/abnormallyIncreasedMobilityOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/zp/abnormallyIncreasedMobilityOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..8d6a89d0
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormallyIncreasedMobilityOfAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0077419
diff --git a/src/curation/upheno-fillers/zp/abnormallyIncreasedNumberOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/zp/abnormallyIncreasedNumberOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..c6cfd6eb
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormallyIncreasedNumberOfAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0014240
diff --git a/src/curation/upheno-fillers/zp/abnormallyIncreasedNumberOfAnatomicalEntityInLocation.tsv b/src/curation/upheno-fillers/zp/abnormallyIncreasedNumberOfAnatomicalEntityInLocation.tsv
new file mode 100644
index 00000000..b7121acc
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormallyIncreasedNumberOfAnatomicalEntityInLocation.tsv
@@ -0,0 +1 @@
+anatomical_entity	location	defined_class
diff --git a/src/curation/upheno-fillers/zp/abnormallyIncreasedOccurrenceOfBiologicalProcess.tsv b/src/curation/upheno-fillers/zp/abnormallyIncreasedOccurrenceOfBiologicalProcess.tsv
new file mode 100644
index 00000000..059c85af
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormallyIncreasedOccurrenceOfBiologicalProcess.tsv
@@ -0,0 +1,296 @@
+biological_process	defined_class
+http://purl.obolibrary.org/obo/GO_0006897	http://purl.obolibrary.org/obo/UPHENO_0079254
+http://purl.obolibrary.org/obo/GO_0032007	http://purl.obolibrary.org/obo/UPHENO_0079255
+http://purl.obolibrary.org/obo/GO_0006412	http://purl.obolibrary.org/obo/UPHENO_0079256
+http://purl.obolibrary.org/obo/GO_0046351	http://purl.obolibrary.org/obo/UPHENO_0079257
+http://purl.obolibrary.org/obo/GO_1990266	http://purl.obolibrary.org/obo/UPHENO_0079258
+http://purl.obolibrary.org/obo/GO_0007626	http://purl.obolibrary.org/obo/UPHENO_0079249
+http://purl.obolibrary.org/obo/GO_0040011	http://purl.obolibrary.org/obo/UPHENO_0079259
+http://purl.obolibrary.org/obo/GO_0042552	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0042310	http://purl.obolibrary.org/obo/UPHENO_0079260
+http://purl.obolibrary.org/obo/GO_0042311	http://purl.obolibrary.org/obo/UPHENO_0079261
+http://purl.obolibrary.org/obo/GO_1990708	http://purl.obolibrary.org/obo/UPHENO_0079262
+http://purl.obolibrary.org/obo/GO_0019722	http://purl.obolibrary.org/obo/UPHENO_0083739
+http://purl.obolibrary.org/obo/GO_0008283	http://purl.obolibrary.org/obo/UPHENO_0079263
+http://purl.obolibrary.org/obo/GO_0030182	http://purl.obolibrary.org/obo/UPHENO_0079264
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diff --git a/src/curation/upheno-fillers/zp/abnormallyIncreasedOccurrenceOfBiologicalProcessInLocation.tsv b/src/curation/upheno-fillers/zp/abnormallyIncreasedOccurrenceOfBiologicalProcessInLocation.tsv
new file mode 100644
index 00000000..1ff90430
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormallyIncreasedOccurrenceOfBiologicalProcessInLocation.tsv
@@ -0,0 +1 @@
+biological_process	location	defined_class
diff --git a/src/curation/upheno-fillers/zp/abnormallyIncreasedPigmentationOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/zp/abnormallyIncreasedPigmentationOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..3715f319
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormallyIncreasedPigmentationOfAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0010666
diff --git a/src/curation/upheno-fillers/zp/abnormallyIncreasedQualityOfBiologicalProcess.tsv b/src/curation/upheno-fillers/zp/abnormallyIncreasedQualityOfBiologicalProcess.tsv
new file mode 100644
index 00000000..d4df4e8a
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormallyIncreasedQualityOfBiologicalProcess.tsv
@@ -0,0 +1,156 @@
+biological_process	defined_class
+http://purl.obolibrary.org/obo/GO_0003266	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0032526	http://purl.obolibrary.org/obo/UPHENO_0080663
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+http://purl.obolibrary.org/obo/GO_0001885	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0006814	http://purl.obolibrary.org/obo/UPHENO_0080665
+http://purl.obolibrary.org/obo/GO_0007626	http://purl.obolibrary.org/obo/UPHENO_0080666
+http://purl.obolibrary.org/obo/GO_0048010	http://purl.obolibrary.org/obo/UPHENO_0080667
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diff --git a/src/curation/upheno-fillers/zp/abnormallyIncreasedQualityOfBiologicalProcessInLocation.tsv b/src/curation/upheno-fillers/zp/abnormallyIncreasedQualityOfBiologicalProcessInLocation.tsv
new file mode 100644
index 00000000..1ff90430
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormallyIncreasedQualityOfBiologicalProcessInLocation.tsv
@@ -0,0 +1 @@
+biological_process	location	defined_class
diff --git a/src/curation/upheno-fillers/zp/abnormallyIncreasedRateOfBiologicalProcess.tsv b/src/curation/upheno-fillers/zp/abnormallyIncreasedRateOfBiologicalProcess.tsv
new file mode 100644
index 00000000..72ce23db
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormallyIncreasedRateOfBiologicalProcess.tsv
@@ -0,0 +1,67 @@
+biological_process	defined_class
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+http://purl.obolibrary.org/obo/GO_0043133	http://purl.obolibrary.org/obo/UPHENO_0055299
+http://purl.obolibrary.org/obo/GO_0007631	http://purl.obolibrary.org/obo/UPHENO_0055147
+http://purl.obolibrary.org/obo/GO_0009060	http://purl.obolibrary.org/obo/UPHENO_0055302
+http://purl.obolibrary.org/obo/GO_0009061	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0060038	http://purl.obolibrary.org/obo/UPHENO_0055303
+http://purl.obolibrary.org/obo/GO_0001539	http://purl.obolibrary.org/obo/UPHENO_0055188
+http://purl.obolibrary.org/obo/GO_0031101	http://purl.obolibrary.org/obo/UPHENO_0055268
diff --git a/src/curation/upheno-fillers/zp/abnormallyIncreasedRateOfBiologicalProcessInLocation.tsv b/src/curation/upheno-fillers/zp/abnormallyIncreasedRateOfBiologicalProcessInLocation.tsv
new file mode 100644
index 00000000..1ff90430
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormallyIncreasedRateOfBiologicalProcessInLocation.tsv
@@ -0,0 +1 @@
+biological_process	location	defined_class
diff --git a/src/curation/upheno-fillers/zp/abnormallyIncreasedRateOfContinuousBiologicalProcess.tsv b/src/curation/upheno-fillers/zp/abnormallyIncreasedRateOfContinuousBiologicalProcess.tsv
new file mode 100644
index 00000000..d9616c72
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormallyIncreasedRateOfContinuousBiologicalProcess.tsv
@@ -0,0 +1,3 @@
+biological_process	defined_class
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0060047	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/zp/abnormallyIncreasedRateOfMolecularFunction.tsv b/src/curation/upheno-fillers/zp/abnormallyIncreasedRateOfMolecularFunction.tsv
new file mode 100644
index 00000000..022a6e84
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormallyIncreasedRateOfMolecularFunction.tsv
@@ -0,0 +1,4 @@
+molecular_function	defined_class
+http://purl.obolibrary.org/obo/GO_0004708	http://purl.obolibrary.org/obo/UPHENO_0048684
+http://purl.obolibrary.org/obo/GO_0004197	http://purl.obolibrary.org/obo/UPHENO_0048685
+http://purl.obolibrary.org/obo/GO_0003674	http://purl.obolibrary.org/obo/UPHENO_0048661
diff --git a/src/curation/upheno-fillers/zp/abnormallyIncreasedSizeOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/zp/abnormallyIncreasedSizeOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..14f0e520
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormallyIncreasedSizeOfAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0001072
diff --git a/src/curation/upheno-fillers/zp/abnormallyIncreasedSizeOfAnatomicalEntityInLocation.tsv b/src/curation/upheno-fillers/zp/abnormallyIncreasedSizeOfAnatomicalEntityInLocation.tsv
new file mode 100644
index 00000000..b7121acc
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormallyIncreasedSizeOfAnatomicalEntityInLocation.tsv
@@ -0,0 +1 @@
+anatomical_entity	location	defined_class
diff --git a/src/curation/upheno-fillers/zp/abnormallyIncreasedSpeedOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/zp/abnormallyIncreasedSpeedOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..91920129
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormallyIncreasedSpeedOfAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0080426
diff --git a/src/curation/upheno-fillers/zp/abnormallyIncreasedThicknessOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/zp/abnormallyIncreasedThicknessOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..0ca1e044
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormallyIncreasedThicknessOfAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0047821
diff --git a/src/curation/upheno-fillers/zp/abnormallyIncreasedThicknessOfAnatomicalEntityInLocation.tsv b/src/curation/upheno-fillers/zp/abnormallyIncreasedThicknessOfAnatomicalEntityInLocation.tsv
new file mode 100644
index 00000000..b7121acc
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormallyIncreasedThicknessOfAnatomicalEntityInLocation.tsv
@@ -0,0 +1 @@
+anatomical_entity	location	defined_class
diff --git a/src/curation/upheno-fillers/zp/abnormallyIncreasedVolumeOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/zp/abnormallyIncreasedVolumeOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..71147114
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormallyIncreasedVolumeOfAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0084715
diff --git a/src/curation/upheno-fillers/zp/abnormallyIncreasedWeightOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/zp/abnormallyIncreasedWeightOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..f603c0cf
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormallyIncreasedWeightOfAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0008273
diff --git a/src/curation/upheno-fillers/zp/abnormallyIncreasedWidthOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/zp/abnormallyIncreasedWidthOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..a0f1a8f6
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormallyIncreasedWidthOfAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0006161
diff --git a/src/curation/upheno-fillers/zp/abnormallyIncreasedWidthOfAnatomicalEntityInLocation.tsv b/src/curation/upheno-fillers/zp/abnormallyIncreasedWidthOfAnatomicalEntityInLocation.tsv
new file mode 100644
index 00000000..b7121acc
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormallyIncreasedWidthOfAnatomicalEntityInLocation.tsv
@@ -0,0 +1 @@
+anatomical_entity	location	defined_class
diff --git a/src/curation/upheno-fillers/zp/abnormallyInvertedAnatomicalEntityInLocation.tsv b/src/curation/upheno-fillers/zp/abnormallyInvertedAnatomicalEntityInLocation.tsv
new file mode 100644
index 00000000..b7121acc
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormallyInvertedAnatomicalEntityInLocation.tsv
@@ -0,0 +1 @@
+anatomical_entity	location	defined_class
diff --git a/src/curation/upheno-fillers/zp/abnormallyOpaqueAnatomicalEntity.tsv b/src/curation/upheno-fillers/zp/abnormallyOpaqueAnatomicalEntity.tsv
new file mode 100644
index 00000000..57c76cbb
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormallyOpaqueAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/zp/abnormallyOpenAnatomicalEntity.tsv b/src/curation/upheno-fillers/zp/abnormallyOpenAnatomicalEntity.tsv
new file mode 100644
index 00000000..c504ed48
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormallyOpenAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0075655
diff --git a/src/curation/upheno-fillers/zp/abnormallyPatchyPigmentationOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/zp/abnormallyPatchyPigmentationOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..57c76cbb
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormallyPatchyPigmentationOfAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/zp/abnormallyPrematureBiologicalProcess.tsv b/src/curation/upheno-fillers/zp/abnormallyPrematureBiologicalProcess.tsv
new file mode 100644
index 00000000..f3658b20
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormallyPrematureBiologicalProcess.tsv
@@ -0,0 +1,31 @@
+biological_process	defined_class
+http://purl.obolibrary.org/obo/GO_0038092	http://purl.obolibrary.org/obo/UPHENO_0049500
+http://purl.obolibrary.org/obo/GO_0006413	http://purl.obolibrary.org/obo/UPHENO_0049472
+http://purl.obolibrary.org/obo/GO_0001541	http://purl.obolibrary.org/obo/UPHENO_0049501
+http://purl.obolibrary.org/obo/GO_0003006	http://purl.obolibrary.org/obo/UPHENO_0049451
+http://purl.obolibrary.org/obo/GO_0048232	http://purl.obolibrary.org/obo/UPHENO_0049502
+http://purl.obolibrary.org/obo/GO_0001964	http://purl.obolibrary.org/obo/UPHENO_0084757
+http://purl.obolibrary.org/obo/GO_0006396	http://purl.obolibrary.org/obo/UPHENO_0049504
+http://purl.obolibrary.org/obo/GO_0008354	http://purl.obolibrary.org/obo/UPHENO_0049525
+http://purl.obolibrary.org/obo/GO_0061053	http://purl.obolibrary.org/obo/UPHENO_0049474
+http://purl.obolibrary.org/obo/GO_0009790	http://purl.obolibrary.org/obo/UPHENO_0049506
+http://purl.obolibrary.org/obo/GO_0042552	http://purl.obolibrary.org/obo/UPHENO_0049476
+http://purl.obolibrary.org/obo/GO_0050936	http://purl.obolibrary.org/obo/UPHENO_0049528
+http://purl.obolibrary.org/obo/GO_0030182	http://purl.obolibrary.org/obo/UPHENO_0049479
+http://purl.obolibrary.org/obo/GO_0035476	http://purl.obolibrary.org/obo/UPHENO_0049481
+http://purl.obolibrary.org/obo/GO_0001503	http://purl.obolibrary.org/obo/UPHENO_0049441
+http://purl.obolibrary.org/obo/GO_0003309	http://purl.obolibrary.org/obo/UPHENO_0049483
+http://purl.obolibrary.org/obo/GO_0048922	http://purl.obolibrary.org/obo/UPHENO_0049485
+http://purl.obolibrary.org/obo/GO_0003415	http://purl.obolibrary.org/obo/UPHENO_0049486
+http://purl.obolibrary.org/obo/GO_0048885	http://purl.obolibrary.org/obo/UPHENO_0049487
+http://purl.obolibrary.org/obo/GO_0030316	http://purl.obolibrary.org/obo/UPHENO_0049533
+http://purl.obolibrary.org/obo/GO_0043010	http://purl.obolibrary.org/obo/UPHENO_0049556
+http://purl.obolibrary.org/obo/GO_0002040	http://purl.obolibrary.org/obo/UPHENO_0049489
+http://purl.obolibrary.org/obo/GO_0048669	http://purl.obolibrary.org/obo/UPHENO_0049558
+http://purl.obolibrary.org/obo/GO_0002063	http://purl.obolibrary.org/obo/UPHENO_0049517
+http://purl.obolibrary.org/obo/GO_0060612	http://purl.obolibrary.org/obo/UPHENO_0049537
+http://purl.obolibrary.org/obo/GO_0035188	http://purl.obolibrary.org/obo/UPHENO_0049563
+http://purl.obolibrary.org/obo/GO_0008150	http://purl.obolibrary.org/obo/UPHENO_0049440
+http://purl.obolibrary.org/obo/GO_0055010	http://purl.obolibrary.org/obo/UPHENO_0049540
+http://purl.obolibrary.org/obo/GO_1990636	http://purl.obolibrary.org/obo/UPHENO_0083017
+http://purl.obolibrary.org/obo/GO_0001958	http://purl.obolibrary.org/obo/UPHENO_0049445
diff --git a/src/curation/upheno-fillers/zp/abnormallyPrematureBiologicalProcessInLocation.tsv b/src/curation/upheno-fillers/zp/abnormallyPrematureBiologicalProcessInLocation.tsv
new file mode 100644
index 00000000..1ff90430
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormallyPrematureBiologicalProcessInLocation.tsv
@@ -0,0 +1 @@
+biological_process	location	defined_class
diff --git a/src/curation/upheno-fillers/zp/abnormallyProminentAnatomicalEntity.tsv b/src/curation/upheno-fillers/zp/abnormallyProminentAnatomicalEntity.tsv
new file mode 100644
index 00000000..2a1ae2f4
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormallyProminentAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0082900
diff --git a/src/curation/upheno-fillers/zp/abnormallyProtrudingAnatomicalEntity.tsv b/src/curation/upheno-fillers/zp/abnormallyProtrudingAnatomicalEntity.tsv
new file mode 100644
index 00000000..57c76cbb
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormallyProtrudingAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/zp/abnormallyProtrudingAnatomicalEntityInLocation.tsv b/src/curation/upheno-fillers/zp/abnormallyProtrudingAnatomicalEntityInLocation.tsv
new file mode 100644
index 00000000..b7121acc
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormallyProtrudingAnatomicalEntityInLocation.tsv
@@ -0,0 +1 @@
+anatomical_entity	location	defined_class
diff --git a/src/curation/upheno-fillers/zp/abnormallyPunctateAnatomicalEntity.tsv b/src/curation/upheno-fillers/zp/abnormallyPunctateAnatomicalEntity.tsv
new file mode 100644
index 00000000..525cc3dd
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormallyPunctateAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0084708
diff --git a/src/curation/upheno-fillers/zp/abnormallyPunctateAnatomicalEntityInLocation.tsv b/src/curation/upheno-fillers/zp/abnormallyPunctateAnatomicalEntityInLocation.tsv
new file mode 100644
index 00000000..b7121acc
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormallyPunctateAnatomicalEntityInLocation.tsv
@@ -0,0 +1 @@
+anatomical_entity	location	defined_class
diff --git a/src/curation/upheno-fillers/zp/abnormallyRotatedAnatomicalEntity.tsv b/src/curation/upheno-fillers/zp/abnormallyRotatedAnatomicalEntity.tsv
new file mode 100644
index 00000000..9ecc5e2d
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormallyRotatedAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0082022
diff --git a/src/curation/upheno-fillers/zp/abnormallySegmentedAnatomicalEntityInLocation.tsv b/src/curation/upheno-fillers/zp/abnormallySegmentedAnatomicalEntityInLocation.tsv
new file mode 100644
index 00000000..b7121acc
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/abnormallySegmentedAnatomicalEntityInLocation.tsv
@@ -0,0 +1 @@
+anatomical_entity	location	defined_class
diff --git a/src/curation/upheno-fillers/zp/aplasticAnatomicalEntity.tsv b/src/curation/upheno-fillers/zp/aplasticAnatomicalEntity.tsv
new file mode 100644
index 00000000..03cb1b52
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/aplasticAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0081451
diff --git a/src/curation/upheno-fillers/zp/aplasticHypoplasticAnatomicalEntity.tsv b/src/curation/upheno-fillers/zp/aplasticHypoplasticAnatomicalEntity.tsv
new file mode 100644
index 00000000..bbfea9cd
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/aplasticHypoplasticAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0080079
diff --git a/src/curation/upheno-fillers/zp/atreticAnatomicalEntity.tsv b/src/curation/upheno-fillers/zp/atreticAnatomicalEntity.tsv
new file mode 100644
index 00000000..61fa7b4a
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/atreticAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0063565
diff --git a/src/curation/upheno-fillers/zp/atrophiedAnatomicalEntity.tsv b/src/curation/upheno-fillers/zp/atrophiedAnatomicalEntity.tsv
new file mode 100644
index 00000000..fc7fbf01
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/atrophiedAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0013936
diff --git a/src/curation/upheno-fillers/zp/bifurcatedAnatomicalEntity.tsv b/src/curation/upheno-fillers/zp/bifurcatedAnatomicalEntity.tsv
new file mode 100644
index 00000000..3ebc6585
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/bifurcatedAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0055805
diff --git a/src/curation/upheno-fillers/zp/bifurcatedAnatomicalEntityInLocation.tsv b/src/curation/upheno-fillers/zp/bifurcatedAnatomicalEntityInLocation.tsv
new file mode 100644
index 00000000..b7121acc
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/bifurcatedAnatomicalEntityInLocation.tsv
@@ -0,0 +1 @@
+anatomical_entity	location	defined_class
diff --git a/src/curation/upheno-fillers/zp/blisteredAnatomicalEntity.tsv b/src/curation/upheno-fillers/zp/blisteredAnatomicalEntity.tsv
new file mode 100644
index 00000000..7e346631
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/blisteredAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0011967
diff --git a/src/curation/upheno-fillers/zp/blisteredAnatomicalEntityInLocation.tsv b/src/curation/upheno-fillers/zp/blisteredAnatomicalEntityInLocation.tsv
new file mode 100644
index 00000000..b7121acc
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/blisteredAnatomicalEntityInLocation.tsv
@@ -0,0 +1 @@
+anatomical_entity	location	defined_class
diff --git a/src/curation/upheno-fillers/zp/brokenAnatomicalEntity.tsv b/src/curation/upheno-fillers/zp/brokenAnatomicalEntity.tsv
new file mode 100644
index 00000000..596162c0
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/brokenAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0081401
diff --git a/src/curation/upheno-fillers/zp/calcifiedAnatomicalEntity.tsv b/src/curation/upheno-fillers/zp/calcifiedAnatomicalEntity.tsv
new file mode 100644
index 00000000..09c9a97e
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/calcifiedAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0067765
diff --git a/src/curation/upheno-fillers/zp/collapsedAnatomicalEntity.tsv b/src/curation/upheno-fillers/zp/collapsedAnatomicalEntity.tsv
new file mode 100644
index 00000000..57c76cbb
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/collapsedAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/zp/cystInLocation-modified.tsv b/src/curation/upheno-fillers/zp/cystInLocation-modified.tsv
new file mode 100644
index 00000000..57c76cbb
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/cystInLocation-modified.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/zp/cystInLocation.tsv b/src/curation/upheno-fillers/zp/cystInLocation.tsv
new file mode 100644
index 00000000..b38e4b3a
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/cystInLocation.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0081065
diff --git a/src/curation/upheno-fillers/zp/damagedAnatomicalEntityInLocation.tsv b/src/curation/upheno-fillers/zp/damagedAnatomicalEntityInLocation.tsv
new file mode 100644
index 00000000..b7121acc
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/damagedAnatomicalEntityInLocation.tsv
@@ -0,0 +1 @@
+anatomical_entity	location	defined_class
diff --git a/src/curation/upheno-fillers/zp/delaminatedAnatomicalEntity.tsv b/src/curation/upheno-fillers/zp/delaminatedAnatomicalEntity.tsv
new file mode 100644
index 00000000..57c76cbb
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/delaminatedAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/zp/dislocatedAnatomicalEntity.tsv b/src/curation/upheno-fillers/zp/dislocatedAnatomicalEntity.tsv
new file mode 100644
index 00000000..57c76cbb
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/dislocatedAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/zp/disorganizedAnatomicalEntity.tsv b/src/curation/upheno-fillers/zp/disorganizedAnatomicalEntity.tsv
new file mode 100644
index 00000000..86f147d1
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/disorganizedAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0084685
diff --git a/src/curation/upheno-fillers/zp/dysplasticAnatomicalEntity.tsv b/src/curation/upheno-fillers/zp/dysplasticAnatomicalEntity.tsv
new file mode 100644
index 00000000..156df18d
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/dysplasticAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0047299
diff --git a/src/curation/upheno-fillers/zp/edematousAnatomicalEntity.tsv b/src/curation/upheno-fillers/zp/edematousAnatomicalEntity.tsv
new file mode 100644
index 00000000..b9751032
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/edematousAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0082498
diff --git a/src/curation/upheno-fillers/zp/exsertedAnatomicalEntity.tsv b/src/curation/upheno-fillers/zp/exsertedAnatomicalEntity.tsv
new file mode 100644
index 00000000..57c76cbb
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/exsertedAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/zp/fibroticAnatomicalEntity.tsv b/src/curation/upheno-fillers/zp/fibroticAnatomicalEntity.tsv
new file mode 100644
index 00000000..e461b3a3
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/fibroticAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0076294
diff --git a/src/curation/upheno-fillers/zp/foldedAnatomicalEntity.tsv b/src/curation/upheno-fillers/zp/foldedAnatomicalEntity.tsv
new file mode 100644
index 00000000..57c76cbb
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/foldedAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/zp/fracturedAnatomicalEntity.tsv b/src/curation/upheno-fillers/zp/fracturedAnatomicalEntity.tsv
new file mode 100644
index 00000000..910caa65
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/fracturedAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0080438
diff --git a/src/curation/upheno-fillers/zp/fracturedAnatomicalEntityByFractureType.tsv b/src/curation/upheno-fillers/zp/fracturedAnatomicalEntityByFractureType.tsv
new file mode 100644
index 00000000..71597e54
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/fracturedAnatomicalEntityByFractureType.tsv
@@ -0,0 +1,3 @@
+anatomical_entity	fractured	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0040034	http://purl.obolibrary.org/obo/UPHENO_0081625
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0040040	http://purl.obolibrary.org/obo/UPHENO_0081627
diff --git a/src/curation/upheno-fillers/zp/herniatedAnatomicalEntity.tsv b/src/curation/upheno-fillers/zp/herniatedAnatomicalEntity.tsv
new file mode 100644
index 00000000..57c76cbb
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/herniatedAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/zp/hyperplasticAnatomicalEntity.tsv b/src/curation/upheno-fillers/zp/hyperplasticAnatomicalEntity.tsv
new file mode 100644
index 00000000..0e2c837a
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/hyperplasticAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0083530
diff --git a/src/curation/upheno-fillers/zp/hypertrophicAnatomicalEntity.tsv b/src/curation/upheno-fillers/zp/hypertrophicAnatomicalEntity.tsv
new file mode 100644
index 00000000..0f0a3168
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/hypertrophicAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0010000	http://purl.obolibrary.org/obo/UPHENO_0084489
diff --git a/src/curation/upheno-fillers/zp/hypoplasticAnatomicalEntity.tsv b/src/curation/upheno-fillers/zp/hypoplasticAnatomicalEntity.tsv
new file mode 100644
index 00000000..e31fa94a
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/hypoplasticAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0081091
diff --git a/src/curation/upheno-fillers/zp/hypoplasticAnatomicalEntityInLocation.tsv b/src/curation/upheno-fillers/zp/hypoplasticAnatomicalEntityInLocation.tsv
new file mode 100644
index 00000000..b7121acc
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/hypoplasticAnatomicalEntityInLocation.tsv
@@ -0,0 +1 @@
+anatomical_entity	location	defined_class
diff --git a/src/curation/upheno-fillers/zp/lesionedAnatomicalEntity.tsv b/src/curation/upheno-fillers/zp/lesionedAnatomicalEntity.tsv
new file mode 100644
index 00000000..b8d459b6
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/lesionedAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0082742
diff --git a/src/curation/upheno-fillers/zp/lysedAnatomicalEntity.tsv b/src/curation/upheno-fillers/zp/lysedAnatomicalEntity.tsv
new file mode 100644
index 00000000..57c76cbb
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/lysedAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/zp/malformedAnatomicalEntity.tsv b/src/curation/upheno-fillers/zp/malformedAnatomicalEntity.tsv
new file mode 100644
index 00000000..35753f91
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/malformedAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0071309
diff --git a/src/curation/upheno-fillers/zp/malformedAnatomicalEntityByType.tsv b/src/curation/upheno-fillers/zp/malformedAnatomicalEntityByType.tsv
new file mode 100644
index 00000000..284a2317
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/malformedAnatomicalEntityByType.tsv
@@ -0,0 +1,10 @@
+anatomical_entity	malformed	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0000646	http://purl.obolibrary.org/obo/UPHENO_0076957
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0030001	http://purl.obolibrary.org/obo/UPHENO_0076960
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0001465	http://purl.obolibrary.org/obo/UPHENO_0076970
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0030007	http://purl.obolibrary.org/obo/UPHENO_0076962
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0000630	http://purl.obolibrary.org/obo/UPHENO_0076964
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0000620	http://purl.obolibrary.org/obo/UPHENO_0076965
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0000636	http://purl.obolibrary.org/obo/UPHENO_0076967
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0030003	http://purl.obolibrary.org/obo/UPHENO_0076966
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/PATO_0000615	http://purl.obolibrary.org/obo/UPHENO_0076969
diff --git a/src/curation/upheno-fillers/zp/malformedAnatomicalEntityInLocation.tsv b/src/curation/upheno-fillers/zp/malformedAnatomicalEntityInLocation.tsv
new file mode 100644
index 00000000..b7121acc
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/malformedAnatomicalEntityInLocation.tsv
@@ -0,0 +1 @@
+anatomical_entity	location	defined_class
diff --git a/src/curation/upheno-fillers/zp/metaplasticAnatomicalEntity.tsv b/src/curation/upheno-fillers/zp/metaplasticAnatomicalEntity.tsv
new file mode 100644
index 00000000..c41e002a
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/metaplasticAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0080376
diff --git a/src/curation/upheno-fillers/zp/mislocalisedAnatomicalEntity.tsv b/src/curation/upheno-fillers/zp/mislocalisedAnatomicalEntity.tsv
new file mode 100644
index 00000000..32fe049b
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/mislocalisedAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0053580
diff --git a/src/curation/upheno-fillers/zp/mislocalisedAnatomicalEntityInLocation.tsv b/src/curation/upheno-fillers/zp/mislocalisedAnatomicalEntityInLocation.tsv
new file mode 100644
index 00000000..b7121acc
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/mislocalisedAnatomicalEntityInLocation.tsv
@@ -0,0 +1 @@
+anatomical_entity	location	defined_class
diff --git a/src/curation/upheno-fillers/zp/necroticAnatomicalEntity.tsv b/src/curation/upheno-fillers/zp/necroticAnatomicalEntity.tsv
new file mode 100644
index 00000000..0d65a24a
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/necroticAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0081698
diff --git a/src/curation/upheno-fillers/zp/neoplasticAnatomicalEntity.tsv b/src/curation/upheno-fillers/zp/neoplasticAnatomicalEntity.tsv
new file mode 100644
index 00000000..6cc392b9
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/neoplasticAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0081769
diff --git a/src/curation/upheno-fillers/zp/non-functionalAnatomicalEntity.tsv b/src/curation/upheno-fillers/zp/non-functionalAnatomicalEntity.tsv
new file mode 100644
index 00000000..57c76cbb
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/non-functionalAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/zp/obstructedAnatomicalEntity.tsv b/src/curation/upheno-fillers/zp/obstructedAnatomicalEntity.tsv
new file mode 100644
index 00000000..0d844bf9
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/obstructedAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_space	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/zp/paralysedAnatomicalEntity.tsv b/src/curation/upheno-fillers/zp/paralysedAnatomicalEntity.tsv
new file mode 100644
index 00000000..c3012971
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/paralysedAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0081700
diff --git a/src/curation/upheno-fillers/zp/perforateAnatomicalEntity.tsv b/src/curation/upheno-fillers/zp/perforateAnatomicalEntity.tsv
new file mode 100644
index 00000000..57c76cbb
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/perforateAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/zp/spatialDeviationOfAnatomicalEntity.tsv b/src/curation/upheno-fillers/zp/spatialDeviationOfAnatomicalEntity.tsv
new file mode 100644
index 00000000..57c76cbb
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/spatialDeviationOfAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0084757
diff --git a/src/curation/upheno-fillers/zp/wrinkledAnatomicalEntity.tsv b/src/curation/upheno-fillers/zp/wrinkledAnatomicalEntity.tsv
new file mode 100644
index 00000000..57c76cbb
--- /dev/null
+++ b/src/curation/upheno-fillers/zp/wrinkledAnatomicalEntity.tsv
@@ -0,0 +1,2 @@
+anatomical_entity	defined_class
+http://purl.obolibrary.org/obo/UBERON_0001062	http://purl.obolibrary.org/obo/UPHENO_0084757