diff --git a/nrf_802154/driver/src/nrf_802154_peripherals_nrf52.h b/nrf_802154/driver/src/nrf_802154_peripherals_nrf52.h
index 3295722ed1..562b88bbdc 100644
--- a/nrf_802154/driver/src/nrf_802154_peripherals_nrf52.h
+++ b/nrf_802154/driver/src/nrf_802154_peripherals_nrf52.h
@@ -43,7 +43,6 @@
 #include <nrfx.h>
 #include "nrf_802154_config.h"
 #include "nrf_802154_debug.h"
-#include "hal/nrf_ppi.h"
 #include "nrf_802154_sl_periphs.h"
 
 #ifdef __cplusplus
@@ -113,7 +112,7 @@ extern "C" {
  *
  */
 #ifndef NRF_802154_PPI_RADIO_RAMP_UP_TRIGG
-#define NRF_802154_PPI_RADIO_RAMP_UP_TRIGG NRF_PPI_CHANNEL6
+#define NRF_802154_PPI_RADIO_RAMP_UP_TRIGG 6U
 #endif
 
 /**
@@ -126,7 +125,7 @@ extern "C" {
  *
  */
 #ifndef NRF_802154_PPI_RADIO_DISABLED_TO_EGU
-#define NRF_802154_PPI_RADIO_DISABLED_TO_EGU NRF_PPI_CHANNEL6
+#define NRF_802154_PPI_RADIO_DISABLED_TO_EGU 6U
 #endif
 
 /**
@@ -138,7 +137,7 @@ extern "C" {
  *
  */
 #ifndef NRF_802154_PPI_EGU_TO_RADIO_RAMP_UP
-#define NRF_802154_PPI_EGU_TO_RADIO_RAMP_UP NRF_PPI_CHANNEL7
+#define NRF_802154_PPI_EGU_TO_RADIO_RAMP_UP 7U
 #endif
 
 /**
@@ -150,7 +149,7 @@ extern "C" {
  *
  */
 #ifndef NRF_802154_PPI_EGU_TO_TIMER_START
-#define NRF_802154_PPI_EGU_TO_TIMER_START NRF_PPI_CHANNEL8
+#define NRF_802154_PPI_EGU_TO_TIMER_START 8U
 #endif
 
 /**
@@ -164,7 +163,7 @@ extern "C" {
  *
  */
 #ifndef NRF_802154_PPI_RADIO_CRCERROR_TO_TIMER_CLEAR
-#define NRF_802154_PPI_RADIO_CRCERROR_TO_TIMER_CLEAR NRF_PPI_CHANNEL9
+#define NRF_802154_PPI_RADIO_CRCERROR_TO_TIMER_CLEAR 9U
 #endif
 
 /**
@@ -178,7 +177,7 @@ extern "C" {
  *
  */
 #ifndef NRF_802154_PPI_RADIO_CCAIDLE_TO_FEM_GPIOTE
-#define NRF_802154_PPI_RADIO_CCAIDLE_TO_FEM_GPIOTE NRF_PPI_CHANNEL9
+#define NRF_802154_PPI_RADIO_CCAIDLE_TO_FEM_GPIOTE 9U
 #endif
 
 /**
@@ -192,7 +191,7 @@ extern "C" {
  *
  */
 #ifndef NRF_802154_PPI_TIMER_COMPARE_TO_RADIO_TXEN
-#define NRF_802154_PPI_TIMER_COMPARE_TO_RADIO_TXEN NRF_PPI_CHANNEL9
+#define NRF_802154_PPI_TIMER_COMPARE_TO_RADIO_TXEN 9U
 #endif
 
 /**
@@ -205,7 +204,7 @@ extern "C" {
  *
  */
 #ifndef NRF_802154_PPI_RADIO_CCABUSY_TO_RADIO_CCASTART
-#define NRF_802154_PPI_RADIO_CCABUSY_TO_RADIO_CCASTART NRF_PPI_CHANNEL10
+#define NRF_802154_PPI_RADIO_CCABUSY_TO_RADIO_CCASTART 10U
 #endif
 
 /**
@@ -216,7 +215,7 @@ extern "C" {
  *
  */
 #ifndef NRF_802154_PPI_RADIO_SYNC_TO_EGU_SYNC
-#define NRF_802154_PPI_RADIO_SYNC_TO_EGU_SYNC NRF_PPI_CHANNEL11
+#define NRF_802154_PPI_RADIO_SYNC_TO_EGU_SYNC 11U
 #endif
 
 #define NRF_802154_DISABLE_BCC_MATCHING_PPI_CHANNELS_USED_MASK \
@@ -231,7 +230,7 @@ extern "C" {
  *
  */
 #ifndef NRF_802154_PPI_CORE_GROUP
-#define NRF_802154_PPI_CORE_GROUP NRF_PPI_CHANNEL_GROUP0
+#define NRF_802154_PPI_CORE_GROUP 0U
 #endif
 
 /**
@@ -241,7 +240,7 @@ extern "C" {
  *
  */
 #ifndef NRF_802154_PPI_ABORT_GROUP
-#define NRF_802154_PPI_ABORT_GROUP NRF_PPI_CHANNEL_GROUP1
+#define NRF_802154_PPI_ABORT_GROUP 1U
 #endif
 
 /**
diff --git a/nrf_802154/sl/sl/include/nrf_802154_sl_periphs.h b/nrf_802154/sl/sl/include/nrf_802154_sl_periphs.h
index 956c70b45b..c1d1557ce7 100644
--- a/nrf_802154/sl/sl/include/nrf_802154_sl_periphs.h
+++ b/nrf_802154/sl/sl/include/nrf_802154_sl_periphs.h
@@ -140,7 +140,7 @@
 #if defined(DPPI_PRESENT)
 #define NRF_802154_PPI_RTC_COMPARE_TO_TIMER_CAPTURE 13U
 #else
-#define NRF_802154_PPI_RTC_COMPARE_TO_TIMER_CAPTURE NRF_PPI_CHANNEL13
+#define NRF_802154_PPI_RTC_COMPARE_TO_TIMER_CAPTURE 13U
 #endif
 #endif
 
@@ -157,7 +157,7 @@
 #if defined(DPPI_PRESENT)
 #define NRF_802154_PPI_TIMESTAMP_EVENT_TO_TIMER_CAPTURE 11U
 #else
-#define NRF_802154_PPI_TIMESTAMP_EVENT_TO_TIMER_CAPTURE NRF_PPI_CHANNEL14
+#define NRF_802154_PPI_TIMESTAMP_EVENT_TO_TIMER_CAPTURE 14U
 #endif
 #endif
 
@@ -181,9 +181,9 @@
  */
 #ifndef NRF_802154_PPI_TIMESTAMP_GROUP
 #if defined(DPPI_PRESENT)
-#define NRF_802154_PPI_TIMESTAMP_GROUP NRF_DPPI_CHANNEL_GROUP1
+#define NRF_802154_PPI_TIMESTAMP_GROUP 1U
 #else
-#define NRF_802154_PPI_TIMESTAMP_GROUP NRF_PPI_CHANNEL_GROUP2
+#define NRF_802154_PPI_TIMESTAMP_GROUP 2U
 #endif
 #endif
 
diff --git a/nrf_802154/sl/sl/lib/nrf54h20_cpurad/hard-float/libnrf-802154-sl.a b/nrf_802154/sl/sl/lib/nrf54h20_cpurad/hard-float/libnrf-802154-sl.a
index 5f8433559b..82295b5929 100644
Binary files a/nrf_802154/sl/sl/lib/nrf54h20_cpurad/hard-float/libnrf-802154-sl.a and b/nrf_802154/sl/sl/lib/nrf54h20_cpurad/hard-float/libnrf-802154-sl.a differ
diff --git a/nrf_802154/sl/sl/lib/nrf54h20_cpurad/soft-float/libnrf-802154-sl.a b/nrf_802154/sl/sl/lib/nrf54h20_cpurad/soft-float/libnrf-802154-sl.a
index 5f8433559b..82295b5929 100644
Binary files a/nrf_802154/sl/sl/lib/nrf54h20_cpurad/soft-float/libnrf-802154-sl.a and b/nrf_802154/sl/sl/lib/nrf54h20_cpurad/soft-float/libnrf-802154-sl.a differ
diff --git a/nrf_802154/sl/sl/lib/nrf54h20_cpurad/softfp-float/libnrf-802154-sl.a b/nrf_802154/sl/sl/lib/nrf54h20_cpurad/softfp-float/libnrf-802154-sl.a
index 5f8433559b..82295b5929 100644
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diff --git a/nrf_802154/sl/sl/lib/nrf54l15_cpuapp/hard-float/libnrf-802154-sl.a b/nrf_802154/sl/sl/lib/nrf54l15_cpuapp/hard-float/libnrf-802154-sl.a
index 71c6a2c226..ecb88f00b2 100644
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diff --git a/nrf_802154/sl/sl/lib/nrf54l15_cpuapp/soft-float/libnrf-802154-sl.a b/nrf_802154/sl/sl/lib/nrf54l15_cpuapp/soft-float/libnrf-802154-sl.a
index 274ac87209..b1f6cef140 100644
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diff --git a/nrf_802154/sl/sl/lib/nrf54l15_cpuapp/softfp-float/libnrf-802154-sl.a b/nrf_802154/sl/sl/lib/nrf54l15_cpuapp/softfp-float/libnrf-802154-sl.a
index 6f7e7eb1ae..e15154b684 100644
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diff --git a/nrf_802154/sl/sl/lib/nrf54l15_cpuapp_ns/hard-float/libnrf-802154-sl.a b/nrf_802154/sl/sl/lib/nrf54l15_cpuapp_ns/hard-float/libnrf-802154-sl.a
index bce0793edb..ff7e76268b 100644
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index b7aaf81f0b..8b1e7610d7 100644
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index 0204979319..44bc33e328 100644
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diff --git a/nrf_802154/sl/sl/lib/nrf54l20_cpuapp/hard-float/libnrf-802154-sl.a b/nrf_802154/sl/sl/lib/nrf54l20_cpuapp/hard-float/libnrf-802154-sl.a
index 71c6a2c226..ecb88f00b2 100644
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diff --git a/nrf_802154/sl/sl/lib/nrf54l20_cpuapp/soft-float/libnrf-802154-sl.a b/nrf_802154/sl/sl/lib/nrf54l20_cpuapp/soft-float/libnrf-802154-sl.a
index 274ac87209..b1f6cef140 100644
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diff --git a/nrf_802154/sl/sl/lib/nrf54l20_cpuapp/softfp-float/libnrf-802154-sl.a b/nrf_802154/sl/sl/lib/nrf54l20_cpuapp/softfp-float/libnrf-802154-sl.a
index 6f7e7eb1ae..e15154b684 100644
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diff --git a/nrf_802154/sl/sl/lib/nrf54l20_cpuapp_ns/hard-float/libnrf-802154-sl.a b/nrf_802154/sl/sl/lib/nrf54l20_cpuapp_ns/hard-float/libnrf-802154-sl.a
index bce0793edb..ff7e76268b 100644
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diff --git a/nrf_802154/sl/sl/lib/nrf54l20_cpuapp_ns/soft-float/libnrf-802154-sl.a b/nrf_802154/sl/sl/lib/nrf54l20_cpuapp_ns/soft-float/libnrf-802154-sl.a
index b7aaf81f0b..8b1e7610d7 100644
Binary files a/nrf_802154/sl/sl/lib/nrf54l20_cpuapp_ns/soft-float/libnrf-802154-sl.a and b/nrf_802154/sl/sl/lib/nrf54l20_cpuapp_ns/soft-float/libnrf-802154-sl.a differ
diff --git a/nrf_802154/sl/sl/lib/nrf54l20_cpuapp_ns/softfp-float/libnrf-802154-sl.a b/nrf_802154/sl/sl/lib/nrf54l20_cpuapp_ns/softfp-float/libnrf-802154-sl.a
index 0204979319..44bc33e328 100644
Binary files a/nrf_802154/sl/sl/lib/nrf54l20_cpuapp_ns/softfp-float/libnrf-802154-sl.a and b/nrf_802154/sl/sl/lib/nrf54l20_cpuapp_ns/softfp-float/libnrf-802154-sl.a differ
diff --git a/nrf_802154/zephyr/Kconfig.nrfxlib b/nrf_802154/zephyr/Kconfig.nrfxlib
index 613d04bb55..ccb50b7b70 100644
--- a/nrf_802154/zephyr/Kconfig.nrfxlib
+++ b/nrf_802154/zephyr/Kconfig.nrfxlib
@@ -33,7 +33,10 @@ config NRF_802154_SL
 	select SENSOR if NRF_802154_TEMPERATURE_UPDATE
 	select TEMP_NRF5_MPSL if NRF_802154_TEMPERATURE_UPDATE
 	select NRFX_PPI if SOC_COMPATIBLE_NRF52X
-	select NRFX_DPPI if SOC_COMPATIBLE_NRF53X || SOC_SERIES_NRF53X
+	select NRFX_DPPI0 if SOC_COMPATIBLE_NRF53X || SOC_SERIES_NRF53X
+	select NRFX_DPPI20 if SOC_SERIES_NRF54LX
+	select NRFX_PPIB11 if SOC_SERIES_NRF54LX
+	select NRFX_PPIB21 if SOC_SERIES_NRF54LX
 	depends on !NRF_802154_SOURCE_HAL_NORDIC
 	help
 		Use of Nordic Semiconductor proprietary implementation of nRF 802.15.4 Service Layer.