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social-infection

This repository supports Facultative symbiont virulence determines horizontal transmission rate without host strain specificity in Dictyostelium discoideum social amoebas

It contains two directories:

experiment, which contains

  • bonniea_transmission_2023.R - R code used to run statistical analyses using the data files and generate figures
  • host_fitness.clean.20220711.txt - Data from host fitness experiment with columns in the following order
    • host identity
    • symbiont identity
    • MOI (multiplicity of infection) of host-symbiont pairing
    • date of experiment
    • estimated total number of host spores produced by sample
    • percent of host spored infected by symbiont in sample
    • percent of spores produced by sample relative to mean of uninfected controls
    • type of host-symbiont pairing
  • symbiont_transmission.clean.20220711.txt - Data from symbiont transmission experiment with columns in the following order
    • host identity
    • symbiont identity
    • MOI of host-symbiont pairing
    • date of experiment
    • percent of host spores infected by symbiont in sample
    • percent of infected spores that were previously uninfected
    • type of host-symbiont pairing

genomics, which contains

  • GFF files for the three P. bonniea genomes - Predicted intact gene for each symbiont genome
  • assembly_to_set_operations.txt - Description and command-line code for how the GFF files were generated including long read assembly, short read polishing, gene annotation, pseudogene prediction, and set operations
  • virulence_candidates.faa - Protein sequences for the candidate virulence factors identified in the study