diff --git a/.eslintrc.js b/.eslintrc.js
index be332590ba7260..a8ab92feb0338b 100644
--- a/.eslintrc.js
+++ b/.eslintrc.js
@@ -362,5 +362,6 @@ module.exports = {
     btoa: 'readable',
     atob: 'readable',
     performance: 'readable',
+    structuredClone: 'readable',
   },
 };
diff --git a/lib/.eslintrc.yaml b/lib/.eslintrc.yaml
index 49013e1f8ee8b5..9f209505db9c33 100644
--- a/lib/.eslintrc.yaml
+++ b/lib/.eslintrc.yaml
@@ -81,6 +81,8 @@ rules:
       message: "Use `const { performance } = require('perf_hooks');` instead of the global."
     - name: queueMicrotask
       message: "Use `const { queueMicrotask } = require('internal/process/task_queues');` instead of the global."
+    - name: structuredClone
+      message: "Use `const { structuredClone } = require('internal/structured_clone');` instead of the global."
   # Custom rules in tools/eslint-rules
   node-core/lowercase-name-for-primitive: error
   node-core/non-ascii-character: error
diff --git a/lib/internal/bootstrap/node.js b/lib/internal/bootstrap/node.js
index ab63dd0604ea41..ae4eac502803e7 100644
--- a/lib/internal/bootstrap/node.js
+++ b/lib/internal/bootstrap/node.js
@@ -254,6 +254,11 @@ if (!config.noBrowserGlobals) {
   // Non-standard extensions:
   defineOperation(globalThis, 'clearImmediate', timers.clearImmediate);
   defineOperation(globalThis, 'setImmediate', timers.setImmediate);
+
+  const {
+    structuredClone,
+  } = require('internal/structured_clone');
+  defineOperation(globalThis, 'structuredClone', structuredClone);
 }
 
 // Set the per-Environment callback that will be called
diff --git a/lib/internal/structured_clone.js b/lib/internal/structured_clone.js
new file mode 100644
index 00000000000000..1d5d0ed511c9cc
--- /dev/null
+++ b/lib/internal/structured_clone.js
@@ -0,0 +1,21 @@
+'use strict';
+
+const {
+  MessageChannel,
+  receiveMessageOnPort,
+} = require('internal/worker/io');
+
+let channel;
+function structuredClone(value, transfer) {
+  // TODO: Improve this with a more efficient solution that avoids
+  // instantiating a MessageChannel
+  channel ??= new MessageChannel();
+  channel.port1.unref();
+  channel.port2.unref();
+  channel.port1.postMessage(value, transfer);
+  return receiveMessageOnPort(channel.port2).message;
+}
+
+module.exports = {
+  structuredClone
+};
diff --git a/test/common/index.js b/test/common/index.js
index 2ac4538cbea804..18d6444419152d 100644
--- a/test/common/index.js
+++ b/test/common/index.js
@@ -293,6 +293,13 @@ if (global.PerformanceMeasure) {
   knownGlobals.push(global.PerformanceMeasure);
 }
 
+// TODO(@ethan-arrowood): Similar to previous checks, this can be temporary
+// until v16.x is EOL. Once all supported versions have structuredClone we
+// can add this to the list above instead.
+if (global.structuredClone) {
+  knownGlobals.push(global.structuredClone);
+}
+
 function allowGlobals(...allowlist) {
   knownGlobals = knownGlobals.concat(allowlist);
 }
diff --git a/test/fixtures/wpt/README.md b/test/fixtures/wpt/README.md
index 7c795981d793a6..8cd6c98684ebd9 100644
--- a/test/fixtures/wpt/README.md
+++ b/test/fixtures/wpt/README.md
@@ -18,6 +18,7 @@ Last update:
 - hr-time: https://github.com/web-platform-tests/wpt/tree/9910784394/hr-time
 - html/webappapis/atob: https://github.com/web-platform-tests/wpt/tree/f267e1dca6/html/webappapis/atob
 - html/webappapis/microtask-queuing: https://github.com/web-platform-tests/wpt/tree/2c5c3c4c27/html/webappapis/microtask-queuing
+- html/webappapis/structured-clone: https://github.com/web-platform-tests/wpt/tree/47d3fb280c/html/webappapis/structured-clone
 - html/webappapis/timers: https://github.com/web-platform-tests/wpt/tree/5873f2d8f1/html/webappapis/timers
 - interfaces: https://github.com/web-platform-tests/wpt/tree/fc086c82d5/interfaces
 - performance-timeline: https://github.com/web-platform-tests/wpt/tree/17ebc3aea0/performance-timeline
diff --git a/test/fixtures/wpt/html/webappapis/structured-clone/structured-clone-battery-of-tests-harness.js b/test/fixtures/wpt/html/webappapis/structured-clone/structured-clone-battery-of-tests-harness.js
new file mode 100644
index 00000000000000..660477dca4c621
--- /dev/null
+++ b/test/fixtures/wpt/html/webappapis/structured-clone/structured-clone-battery-of-tests-harness.js
@@ -0,0 +1,44 @@
+/**
+ * Runs a collection of tests that determine if an API implements structured clone
+ * correctly.
+ *
+ * The `runner` parameter has the following properties:
+ * - `setup()`: An optional function run once before testing starts
+ * - `teardown()`: An option function run once after all tests are done
+ * - `preTest()`: An optional, async function run before a test
+ * - `postTest()`: An optional, async function run after a test is done
+ * - `structuredClone(obj, transferList)`: Required function that somehow
+ *                                         structurally clones an object.
+ * - `hasDocument`: When true, disables tests that require a document. True by default.
+ */
+
+function runStructuredCloneBatteryOfTests(runner) {
+  const defaultRunner = {
+    setup() {},
+    preTest() {},
+    postTest() {},
+    teardown() {},
+    hasDocument: true
+  };
+  runner = Object.assign({}, defaultRunner, runner);
+
+  let setupPromise = runner.setup();
+  const allTests = structuredCloneBatteryOfTests.map(test => {
+
+    if (!runner.hasDocument && test.requiresDocument) {
+      return;
+    }
+
+    return new Promise(resolve => {
+      promise_test(async _ => {
+        test = await test;
+        await setupPromise;
+        await runner.preTest(test);
+        await test.f(runner)
+        await runner.postTest(test);
+        resolve();
+      }, test.description);
+    }).catch(_ => {});
+  });
+  Promise.all(allTests).then(_ => runner.teardown());
+}
diff --git a/test/fixtures/wpt/html/webappapis/structured-clone/structured-clone-battery-of-tests-with-transferables.js b/test/fixtures/wpt/html/webappapis/structured-clone/structured-clone-battery-of-tests-with-transferables.js
new file mode 100644
index 00000000000000..744f1168196001
--- /dev/null
+++ b/test/fixtures/wpt/html/webappapis/structured-clone/structured-clone-battery-of-tests-with-transferables.js
@@ -0,0 +1,22 @@
+structuredCloneBatteryOfTests.push({
+  description: 'ArrayBuffer',
+  async f(runner) {
+    const buffer = new Uint8Array([1]).buffer;
+    const copy = await runner.structuredClone(buffer, [buffer]);
+    assert_equals(buffer.byteLength, 0);
+    assert_equals(copy.byteLength, 1);
+  }
+});
+
+structuredCloneBatteryOfTests.push({
+  description: 'MessagePort',
+  async f(runner) {
+    const {port1, port2} = new MessageChannel();
+    const copy = await runner.structuredClone(port2, [port2]);
+    const msg = new Promise(resolve => port1.onmessage = resolve);
+    copy.postMessage('ohai');
+    assert_equals((await msg).data, 'ohai');
+  }
+});
+
+// TODO: ImageBitmap
diff --git a/test/fixtures/wpt/html/webappapis/structured-clone/structured-clone-battery-of-tests.js b/test/fixtures/wpt/html/webappapis/structured-clone/structured-clone-battery-of-tests.js
new file mode 100644
index 00000000000000..0c96ded2088357
--- /dev/null
+++ b/test/fixtures/wpt/html/webappapis/structured-clone/structured-clone-battery-of-tests.js
@@ -0,0 +1,618 @@
+/* This file is mostly a remix of @zcorpan’s web worker test suite */
+
+structuredCloneBatteryOfTests = [];
+
+function check(description, input, callback, requiresDocument = false) {
+  testObjMock = {
+    done() {},
+    step_func(f) {return _ => f()},
+  };
+
+  structuredCloneBatteryOfTests.push({
+    description,
+    async f(runner) {
+      let newInput = input;
+      if (typeof input === 'function') {
+        newInput = input();
+      }
+      const copy = await runner.structuredClone(newInput);
+      await callback(copy, newInput, testObjMock);
+    },
+    requiresDocument
+  });
+}
+
+function compare_primitive(actual, input, test_obj) {
+  assert_equals(actual, input);
+  if (test_obj)
+    test_obj.done();
+}
+function compare_Array(callback, callback_is_async) {
+  return function(actual, input, test_obj) {
+    if (typeof actual === 'string')
+      assert_unreached(actual);
+    assert_true(actual instanceof Array, 'instanceof Array');
+    assert_not_equals(actual, input);
+    assert_equals(actual.length, input.length, 'length');
+    callback(actual, input);
+    if (test_obj && !callback_is_async)
+      test_obj.done();
+  }
+}
+
+function compare_Object(callback, callback_is_async) {
+  return function(actual, input, test_obj) {
+    if (typeof actual === 'string')
+      assert_unreached(actual);
+    assert_true(actual instanceof Object, 'instanceof Object');
+    assert_false(actual instanceof Array, 'instanceof Array');
+    assert_not_equals(actual, input);
+    callback(actual, input);
+    if (test_obj && !callback_is_async)
+      test_obj.done();
+  }
+}
+
+function enumerate_props(compare_func, test_obj) {
+  return function(actual, input) {
+    for (const x in input) {
+      compare_func(actual[x], input[x], test_obj);
+    }
+  };
+}
+
+check('primitive undefined', undefined, compare_primitive);
+check('primitive null', null, compare_primitive);
+check('primitive true', true, compare_primitive);
+check('primitive false', false, compare_primitive);
+check('primitive string, empty string', '', compare_primitive);
+check('primitive string, lone high surrogate', '\uD800', compare_primitive);
+check('primitive string, lone low surrogate', '\uDC00', compare_primitive);
+check('primitive string, NUL', '\u0000', compare_primitive);
+check('primitive string, astral character', '\uDBFF\uDFFD', compare_primitive);
+check('primitive number, 0.2', 0.2, compare_primitive);
+check('primitive number, 0', 0, compare_primitive);
+check('primitive number, -0', -0, compare_primitive);
+check('primitive number, NaN', NaN, compare_primitive);
+check('primitive number, Infinity', Infinity, compare_primitive);
+check('primitive number, -Infinity', -Infinity, compare_primitive);
+check('primitive number, 9007199254740992', 9007199254740992, compare_primitive);
+check('primitive number, -9007199254740992', -9007199254740992, compare_primitive);
+check('primitive number, 9007199254740994', 9007199254740994, compare_primitive);
+check('primitive number, -9007199254740994', -9007199254740994, compare_primitive);
+check('primitive BigInt, 0n', 0n, compare_primitive);
+check('primitive BigInt, -0n', -0n, compare_primitive);
+check('primitive BigInt, -9007199254740994000n', -9007199254740994000n, compare_primitive);
+check('primitive BigInt, -9007199254740994000900719925474099400090071992547409940009007199254740994000n', -9007199254740994000900719925474099400090071992547409940009007199254740994000n, compare_primitive);
+
+check('Array primitives', [undefined,
+                           null,
+                           true,
+                           false,
+                           '',
+                           '\uD800',
+                           '\uDC00',
+                           '\u0000',
+                           '\uDBFF\uDFFD',
+                           0.2,
+                           0,
+                           -0,
+                           NaN,
+                           Infinity,
+                           -Infinity,
+                           9007199254740992,
+                           -9007199254740992,
+                           9007199254740994,
+                           -9007199254740994,
+                           -12n,
+                           -0n,
+                           0n], compare_Array(enumerate_props(compare_primitive)));
+check('Object primitives', {'undefined':undefined,
+                           'null':null,
+                           'true':true,
+                           'false':false,
+                           'empty':'',
+                           'high surrogate':'\uD800',
+                           'low surrogate':'\uDC00',
+                           'nul':'\u0000',
+                           'astral':'\uDBFF\uDFFD',
+                           '0.2':0.2,
+                           '0':0,
+                           '-0':-0,
+                           'NaN':NaN,
+                           'Infinity':Infinity,
+                           '-Infinity':-Infinity,
+                           '9007199254740992':9007199254740992,
+                           '-9007199254740992':-9007199254740992,
+                           '9007199254740994':9007199254740994,
+                           '-9007199254740994':-9007199254740994}, compare_Object(enumerate_props(compare_primitive)));
+
+function compare_Boolean(actual, input, test_obj) {
+  if (typeof actual === 'string')
+    assert_unreached(actual);
+  assert_true(actual instanceof Boolean, 'instanceof Boolean');
+  assert_equals(String(actual), String(input), 'converted to primitive');
+  assert_not_equals(actual, input);
+  if (test_obj)
+    test_obj.done();
+}
+check('Boolean true', new Boolean(true), compare_Boolean);
+check('Boolean false', new Boolean(false), compare_Boolean);
+check('Array Boolean objects', [new Boolean(true), new Boolean(false)], compare_Array(enumerate_props(compare_Boolean)));
+check('Object Boolean objects', {'true':new Boolean(true), 'false':new Boolean(false)}, compare_Object(enumerate_props(compare_Boolean)));
+
+function compare_obj(what) {
+  const Type = self[what];
+  return function(actual, input, test_obj) {
+    if (typeof actual === 'string')
+      assert_unreached(actual);
+    assert_true(actual instanceof Type, 'instanceof '+what);
+    assert_equals(Type(actual), Type(input), 'converted to primitive');
+    assert_not_equals(actual, input);
+    if (test_obj)
+      test_obj.done();
+  };
+}
+check('String empty string', new String(''), compare_obj('String'));
+check('String lone high surrogate', new String('\uD800'), compare_obj('String'));
+check('String lone low surrogate', new String('\uDC00'), compare_obj('String'));
+check('String NUL', new String('\u0000'), compare_obj('String'));
+check('String astral character', new String('\uDBFF\uDFFD'), compare_obj('String'));
+check('Array String objects', [new String(''),
+                               new String('\uD800'),
+                               new String('\uDC00'),
+                               new String('\u0000'),
+                               new String('\uDBFF\uDFFD')], compare_Array(enumerate_props(compare_obj('String'))));
+check('Object String objects', {'empty':new String(''),
+                               'high surrogate':new String('\uD800'),
+                               'low surrogate':new String('\uDC00'),
+                               'nul':new String('\u0000'),
+                               'astral':new String('\uDBFF\uDFFD')}, compare_Object(enumerate_props(compare_obj('String'))));
+
+check('Number 0.2', new Number(0.2), compare_obj('Number'));
+check('Number 0', new Number(0), compare_obj('Number'));
+check('Number -0', new Number(-0), compare_obj('Number'));
+check('Number NaN', new Number(NaN), compare_obj('Number'));
+check('Number Infinity', new Number(Infinity), compare_obj('Number'));
+check('Number -Infinity', new Number(-Infinity), compare_obj('Number'));
+check('Number 9007199254740992', new Number(9007199254740992), compare_obj('Number'));
+check('Number -9007199254740992', new Number(-9007199254740992), compare_obj('Number'));
+check('Number 9007199254740994', new Number(9007199254740994), compare_obj('Number'));
+check('Number -9007199254740994', new Number(-9007199254740994), compare_obj('Number'));
+// BigInt does not have a non-throwing constructor
+check('BigInt -9007199254740994n', Object(-9007199254740994n), compare_obj('BigInt'));
+
+check('Array Number objects', [new Number(0.2),
+                               new Number(0),
+                               new Number(-0),
+                               new Number(NaN),
+                               new Number(Infinity),
+                               new Number(-Infinity),
+                               new Number(9007199254740992),
+                               new Number(-9007199254740992),
+                               new Number(9007199254740994),
+                               new Number(-9007199254740994)], compare_Array(enumerate_props(compare_obj('Number'))));
+check('Object Number objects', {'0.2':new Number(0.2),
+                               '0':new Number(0),
+                               '-0':new Number(-0),
+                               'NaN':new Number(NaN),
+                               'Infinity':new Number(Infinity),
+                               '-Infinity':new Number(-Infinity),
+                               '9007199254740992':new Number(9007199254740992),
+                               '-9007199254740992':new Number(-9007199254740992),
+                               '9007199254740994':new Number(9007199254740994),
+                               '-9007199254740994':new Number(-9007199254740994)}, compare_Object(enumerate_props(compare_obj('Number'))));
+
+function compare_Date(actual, input, test_obj) {
+  if (typeof actual === 'string')
+    assert_unreached(actual);
+  assert_true(actual instanceof Date, 'instanceof Date');
+  assert_equals(Number(actual), Number(input), 'converted to primitive');
+  assert_not_equals(actual, input);
+  if (test_obj)
+    test_obj.done();
+}
+check('Date 0', new Date(0), compare_Date);
+check('Date -0', new Date(-0), compare_Date);
+check('Date -8.64e15', new Date(-8.64e15), compare_Date);
+check('Date 8.64e15', new Date(8.64e15), compare_Date);
+check('Array Date objects', [new Date(0),
+                             new Date(-0),
+                             new Date(-8.64e15),
+                             new Date(8.64e15)], compare_Array(enumerate_props(compare_Date)));
+check('Object Date objects', {'0':new Date(0),
+                              '-0':new Date(-0),
+                              '-8.64e15':new Date(-8.64e15),
+                              '8.64e15':new Date(8.64e15)}, compare_Object(enumerate_props(compare_Date)));
+
+function compare_RegExp(expected_source) {
+  // XXX ES6 spec doesn't define exact serialization for `source` (it allows several ways to escape)
+  return function(actual, input, test_obj) {
+    if (typeof actual === 'string')
+      assert_unreached(actual);
+    assert_true(actual instanceof RegExp, 'instanceof RegExp');
+    assert_equals(actual.global, input.global, 'global');
+    assert_equals(actual.ignoreCase, input.ignoreCase, 'ignoreCase');
+    assert_equals(actual.multiline, input.multiline, 'multiline');
+    assert_equals(actual.source, expected_source, 'source');
+    assert_equals(actual.sticky, input.sticky, 'sticky');
+    assert_equals(actual.unicode, input.unicode, 'unicode');
+    assert_equals(actual.lastIndex, 0, 'lastIndex');
+    assert_not_equals(actual, input);
+    if (test_obj)
+      test_obj.done();
+  }
+}
+function func_RegExp_flags_lastIndex() {
+  const r = /foo/gim;
+  r.lastIndex = 2;
+  return r;
+}
+function func_RegExp_sticky() {
+  return new RegExp('foo', 'y');
+}
+function func_RegExp_unicode() {
+  return new RegExp('foo', 'u');
+}
+check('RegExp flags and lastIndex', func_RegExp_flags_lastIndex, compare_RegExp('foo'));
+check('RegExp sticky flag', func_RegExp_sticky, compare_RegExp('foo'));
+check('RegExp unicode flag', func_RegExp_unicode, compare_RegExp('foo'));
+check('RegExp empty', new RegExp(''), compare_RegExp('(?:)'));
+check('RegExp slash', new RegExp('/'), compare_RegExp('\\/'));
+check('RegExp new line', new RegExp('\n'), compare_RegExp('\\n'));
+check('Array RegExp object, RegExp flags and lastIndex', [func_RegExp_flags_lastIndex()], compare_Array(enumerate_props(compare_RegExp('foo'))));
+check('Array RegExp object, RegExp sticky flag', function() { return [func_RegExp_sticky()]; }, compare_Array(enumerate_props(compare_RegExp('foo'))));
+check('Array RegExp object, RegExp unicode flag', function() { return [func_RegExp_unicode()]; }, compare_Array(enumerate_props(compare_RegExp('foo'))));
+check('Array RegExp object, RegExp empty', [new RegExp('')], compare_Array(enumerate_props(compare_RegExp('(?:)'))));
+check('Array RegExp object, RegExp slash', [new RegExp('/')], compare_Array(enumerate_props(compare_RegExp('\\/'))));
+check('Array RegExp object, RegExp new line', [new RegExp('\n')], compare_Array(enumerate_props(compare_RegExp('\\n'))));
+check('Object RegExp object, RegExp flags and lastIndex', {'x':func_RegExp_flags_lastIndex()}, compare_Object(enumerate_props(compare_RegExp('foo'))));
+check('Object RegExp object, RegExp sticky flag', function() { return {'x':func_RegExp_sticky()}; }, compare_Object(enumerate_props(compare_RegExp('foo'))));
+check('Object RegExp object, RegExp unicode flag', function() { return {'x':func_RegExp_unicode()}; }, compare_Object(enumerate_props(compare_RegExp('foo'))));
+check('Object RegExp object, RegExp empty', {'x':new RegExp('')}, compare_Object(enumerate_props(compare_RegExp('(?:)'))));
+check('Object RegExp object, RegExp slash', {'x':new RegExp('/')}, compare_Object(enumerate_props(compare_RegExp('\\/'))));
+check('Object RegExp object, RegExp new line', {'x':new RegExp('\n')}, compare_Object(enumerate_props(compare_RegExp('\\n'))));
+
+async function compare_Blob(actual, input, test_obj, expect_File) {
+  if (typeof actual === 'string')
+    assert_unreached(actual);
+  assert_true(actual instanceof Blob, 'instanceof Blob');
+  if (!expect_File)
+    assert_false(actual instanceof File, 'instanceof File');
+  assert_equals(actual.size, input.size, 'size');
+  assert_equals(actual.type, input.type, 'type');
+  assert_not_equals(actual, input);
+  const ab1 = await new Response(actual).arrayBuffer();
+  const ab2 = await new Response(input).arrayBuffer();
+  assert_equals(ab1.byteLength, ab2.byteLength, 'byteLength');
+  const ta1 = new Uint8Array(ab1);
+  const ta2 = new Uint8Array(ab2);
+  for(let i = 0; i < ta1.size; i++) {
+    assert_equals(ta1[i], ta2[i]);
+  }
+}
+function func_Blob_basic() {
+  return new Blob(['foo'], {type:'text/x-bar'});
+}
+check('Blob basic', func_Blob_basic, compare_Blob);
+
+function b(str) {
+  return parseInt(str, 2);
+}
+function encode_cesu8(codeunits) {
+  // http://www.unicode.org/reports/tr26/ section 2.2
+  // only the 3-byte form is supported
+  const rv = [];
+  codeunits.forEach(function(codeunit) {
+    rv.push(b('11100000') + ((codeunit & b('1111000000000000')) >> 12));
+    rv.push(b('10000000') + ((codeunit & b('0000111111000000')) >> 6));
+    rv.push(b('10000000') +  (codeunit & b('0000000000111111')));
+  });
+  return rv;
+}
+function func_Blob_bytes(arr) {
+  return function() {
+    const buffer = new ArrayBuffer(arr.length);
+    const view = new DataView(buffer);
+    for (let i = 0; i < arr.length; ++i) {
+      view.setUint8(i, arr[i]);
+    }
+    return new Blob([view]);
+  };
+}
+check('Blob unpaired high surrogate (invalid utf-8)', func_Blob_bytes(encode_cesu8([0xD800])), compare_Blob);
+check('Blob unpaired low surrogate (invalid utf-8)', func_Blob_bytes(encode_cesu8([0xDC00])), compare_Blob);
+check('Blob paired surrogates (invalid utf-8)', func_Blob_bytes(encode_cesu8([0xD800, 0xDC00])), compare_Blob);
+
+function func_Blob_empty() {
+  return new Blob(['']);
+}
+check('Blob empty', func_Blob_empty , compare_Blob);
+function func_Blob_NUL() {
+  return new Blob(['\u0000']);
+}
+check('Blob NUL', func_Blob_NUL, compare_Blob);
+
+check('Array Blob object, Blob basic', [func_Blob_basic()], compare_Array(enumerate_props(compare_Blob), true));
+check('Array Blob object, Blob unpaired high surrogate (invalid utf-8)', [func_Blob_bytes([0xD800])()], compare_Array(enumerate_props(compare_Blob), true));
+check('Array Blob object, Blob unpaired low surrogate (invalid utf-8)', [func_Blob_bytes([0xDC00])()], compare_Array(enumerate_props(compare_Blob), true));
+check('Array Blob object, Blob paired surrogates (invalid utf-8)', [func_Blob_bytes([0xD800, 0xDC00])()], compare_Array(enumerate_props(compare_Blob), true));
+check('Array Blob object, Blob empty', [func_Blob_empty()], compare_Array(enumerate_props(compare_Blob), true));
+check('Array Blob object, Blob NUL', [func_Blob_NUL()], compare_Array(enumerate_props(compare_Blob), true));
+check('Array Blob object, two Blobs', [func_Blob_basic(), func_Blob_empty()], compare_Array(enumerate_props(compare_Blob), true));
+
+check('Object Blob object, Blob basic', {'x':func_Blob_basic()}, compare_Object(enumerate_props(compare_Blob), true));
+check('Object Blob object, Blob unpaired high surrogate (invalid utf-8)', {'x':func_Blob_bytes([0xD800])()}, compare_Object(enumerate_props(compare_Blob), true));
+check('Object Blob object, Blob unpaired low surrogate (invalid utf-8)', {'x':func_Blob_bytes([0xDC00])()}, compare_Object(enumerate_props(compare_Blob), true));
+check('Object Blob object, Blob paired surrogates (invalid utf-8)', {'x':func_Blob_bytes([0xD800, 0xDC00])()  }, compare_Object(enumerate_props(compare_Blob), true));
+check('Object Blob object, Blob empty', {'x':func_Blob_empty()}, compare_Object(enumerate_props(compare_Blob), true));
+check('Object Blob object, Blob NUL', {'x':func_Blob_NUL()}, compare_Object(enumerate_props(compare_Blob), true));
+
+function compare_File(actual, input, test_obj) {
+  assert_true(actual instanceof File, 'instanceof File');
+  assert_equals(actual.name, input.name, 'name');
+  assert_equals(actual.lastModified, input.lastModified, 'lastModified');
+  compare_Blob(actual, input, test_obj, true);
+}
+function func_File_basic() {
+  return new File(['foo'], 'bar', {type:'text/x-bar', lastModified:42});
+}
+check('File basic', func_File_basic, compare_File);
+
+function compare_FileList(actual, input, test_obj) {
+  if (typeof actual === 'string')
+    assert_unreached(actual);
+  assert_true(actual instanceof FileList, 'instanceof FileList');
+  assert_equals(actual.length, input.length, 'length');
+  assert_not_equals(actual, input);
+  // XXX when there's a way to populate or construct a FileList,
+  // check the items in the FileList
+  if (test_obj)
+    test_obj.done();
+}
+function func_FileList_empty() {
+  const input = document.createElement('input');
+  input.type = 'file';
+  return input.files;
+}
+check('FileList empty', func_FileList_empty, compare_FileList, true);
+check('Array FileList object, FileList empty', () => ([func_FileList_empty()]), compare_Array(enumerate_props(compare_FileList)), true);
+check('Object FileList object, FileList empty', () => ({'x':func_FileList_empty()}), compare_Object(enumerate_props(compare_FileList)), true);
+
+function compare_ArrayBufferView(view) {
+  const Type = self[view];
+  return function(actual, input, test_obj) {
+    if (typeof actual === 'string')
+      assert_unreached(actual);
+    assert_true(actual instanceof Type, 'instanceof '+view);
+    assert_equals(actual.length, input.length, 'length');
+    assert_not_equals(actual.buffer, input.buffer, 'buffer');
+    for (let i = 0; i < actual.length; ++i) {
+      assert_equals(actual[i], input[i], 'actual['+i+']');
+    }
+    if (test_obj)
+      test_obj.done();
+  };
+}
+function compare_ImageData(actual, input, test_obj) {
+  if (typeof actual === 'string')
+    assert_unreached(actual);
+  assert_equals(actual.width, input.width, 'width');
+  assert_equals(actual.height, input.height, 'height');
+  assert_not_equals(actual.data, input.data, 'data');
+  compare_ArrayBufferView('Uint8ClampedArray')(actual.data, input.data, null);
+  if (test_obj)
+    test_obj.done();
+}
+function func_ImageData_1x1_transparent_black() {
+  const canvas = document.createElement('canvas');
+  const ctx = canvas.getContext('2d');
+  return ctx.createImageData(1, 1);
+}
+check('ImageData 1x1 transparent black', func_ImageData_1x1_transparent_black, compare_ImageData, true);
+function func_ImageData_1x1_non_transparent_non_black() {
+  const canvas = document.createElement('canvas');
+  const ctx = canvas.getContext('2d');
+  const imagedata = ctx.createImageData(1, 1);
+  imagedata.data[0] = 100;
+  imagedata.data[1] = 101;
+  imagedata.data[2] = 102;
+  imagedata.data[3] = 103;
+  return imagedata;
+}
+check('ImageData 1x1 non-transparent non-black', func_ImageData_1x1_non_transparent_non_black, compare_ImageData, true);
+check('Array ImageData object, ImageData 1x1 transparent black', () => ([func_ImageData_1x1_transparent_black()]), compare_Array(enumerate_props(compare_ImageData)), true);
+check('Array ImageData object, ImageData 1x1 non-transparent non-black', () => ([func_ImageData_1x1_non_transparent_non_black()]), compare_Array(enumerate_props(compare_ImageData)), true);
+check('Object ImageData object, ImageData 1x1 transparent black', () => ({'x':func_ImageData_1x1_transparent_black()}), compare_Object(enumerate_props(compare_ImageData)), true);
+check('Object ImageData object, ImageData 1x1 non-transparent non-black', () => ({'x':func_ImageData_1x1_non_transparent_non_black()}), compare_Object(enumerate_props(compare_ImageData)), true);
+
+
+check('Array sparse', new Array(10), compare_Array(enumerate_props(compare_primitive)));
+check('Array with non-index property', function() {
+  const rv = [];
+  rv.foo = 'bar';
+  return rv;
+}, compare_Array(enumerate_props(compare_primitive)));
+check('Object with index property and length', {'0':'foo', 'length':1}, compare_Object(enumerate_props(compare_primitive)));
+function check_circular_property(prop) {
+  return function(actual) {
+    assert_equals(actual[prop], actual);
+  };
+}
+check('Array with circular reference', function() {
+  const rv = [];
+  rv[0] = rv;
+  return rv;
+}, compare_Array(check_circular_property('0')));
+check('Object with circular reference', function() {
+  const rv = {};
+  rv['x'] = rv;
+  return rv;
+}, compare_Object(check_circular_property('x')));
+function check_identical_property_values(prop1, prop2) {
+  return function(actual) {
+    assert_equals(actual[prop1], actual[prop2]);
+  };
+}
+check('Array with identical property values', function() {
+  const obj = {}
+  return [obj, obj];
+}, compare_Array(check_identical_property_values('0', '1')));
+check('Object with identical property values', function() {
+  const obj = {}
+  return {'x':obj, 'y':obj};
+}, compare_Object(check_identical_property_values('x', 'y')));
+
+function check_absent_property(prop) {
+  return function(actual) {
+    assert_false(prop in actual);
+  };
+}
+check('Object with property on prototype', function() {
+  const Foo = function() {};
+  Foo.prototype = {'foo':'bar'};
+  return new Foo();
+}, compare_Object(check_absent_property('foo')));
+
+check('Object with non-enumerable property', function() {
+  const rv = {};
+  Object.defineProperty(rv, 'foo', {value:'bar', enumerable:false, writable:true, configurable:true});
+  return rv;
+}, compare_Object(check_absent_property('foo')));
+
+function check_writable_property(prop) {
+  return function(actual, input) {
+    assert_equals(actual[prop], input[prop]);
+    actual[prop] += ' baz';
+    assert_equals(actual[prop], input[prop] + ' baz');
+  };
+}
+check('Object with non-writable property', function() {
+  const rv = {};
+  Object.defineProperty(rv, 'foo', {value:'bar', enumerable:true, writable:false, configurable:true});
+  return rv;
+}, compare_Object(check_writable_property('foo')));
+
+function check_configurable_property(prop) {
+  return function(actual, input) {
+    assert_equals(actual[prop], input[prop]);
+    delete actual[prop];
+    assert_false('prop' in actual);
+  };
+}
+check('Object with non-configurable property', function() {
+  const rv = {};
+  Object.defineProperty(rv, 'foo', {value:'bar', enumerable:true, writable:true, configurable:false});
+  return rv;
+}, compare_Object(check_configurable_property('foo')));
+
+/* The tests below are inspired by @zcorpan’s work but got some
+more substantial changed due to their previous async setup */
+
+function get_canvas_1x1_transparent_black() {
+  const canvas = document.createElement('canvas');
+  canvas.width = 1;
+  canvas.height = 1;
+  return canvas;
+}
+
+function get_canvas_1x1_non_transparent_non_black() {
+  const canvas = document.createElement('canvas');
+  canvas.width = 1;
+  canvas.height = 1;
+  const ctx = canvas.getContext('2d');
+  const imagedata = ctx.getImageData(0, 0, 1, 1);
+  imagedata.data[0] = 100;
+  imagedata.data[1] = 101;
+  imagedata.data[2] = 102;
+  imagedata.data[3] = 103;
+  return canvas;
+}
+
+function compare_ImageBitmap(actual, input) {
+  if (typeof actual === 'string')
+    assert_unreached(actual);
+  assert_true(actual instanceof ImageBitmap, 'instanceof ImageBitmap');
+  assert_not_equals(actual, input);
+  // XXX paint the ImageBitmap on a canvas and check the data
+}
+
+structuredCloneBatteryOfTests.push({
+  description: 'ImageBitmap 1x1 transparent black',
+  async f(runner) {
+    const canvas = get_canvas_1x1_transparent_black();
+    const bm = await createImageBitmap(canvas);
+    const copy = await runner.structuredClone(bm);
+    compare_ImageBitmap(bm, copy);
+  },
+  requiresDocument: true
+});
+
+structuredCloneBatteryOfTests.push({
+  description: 'ImageBitmap 1x1 non-transparent non-black',
+  async f(runner) {
+    const canvas = get_canvas_1x1_non_transparent_non_black();
+    const bm = await createImageBitmap(canvas);
+    const copy = await runner.structuredClone(bm);
+    compare_ImageBitmap(bm, copy);
+  },
+  requiresDocument: true
+});
+
+structuredCloneBatteryOfTests.push({
+  description: 'Array ImageBitmap object, ImageBitmap 1x1 transparent black',
+  async f(runner) {
+    const canvas = get_canvas_1x1_transparent_black();
+    const bm = [await createImageBitmap(canvas)];
+    const copy = await runner.structuredClone(bm);
+    compare_Array(enumerate_props(compare_ImageBitmap))(bm, copy);
+  },
+  requiresDocument: true
+});
+
+structuredCloneBatteryOfTests.push({
+  description: 'Array ImageBitmap object, ImageBitmap 1x1 transparent non-black',
+  async f(runner) {
+    const canvas = get_canvas_1x1_non_transparent_non_black();
+    const bm = [await createImageBitmap(canvas)];
+    const copy = await runner.structuredClone(bm);
+    compare_Array(enumerate_props(compare_ImageBitmap))(bm, copy);
+  },
+  requiresDocument: true
+});
+
+structuredCloneBatteryOfTests.push({
+  description: 'Object ImageBitmap object, ImageBitmap 1x1 transparent black',
+  async f(runner) {
+    const canvas = get_canvas_1x1_transparent_black();
+    const bm = {x: await createImageBitmap(canvas)};
+    const copy = await runner.structuredClone(bm);
+    compare_Object(enumerate_props(compare_ImageBitmap))(bm, copy);
+  },
+  requiresDocument: true
+});
+
+structuredCloneBatteryOfTests.push({
+  description: 'Object ImageBitmap object, ImageBitmap 1x1 transparent non-black',
+  async f(runner) {
+    const canvas = get_canvas_1x1_non_transparent_non_black();
+    const bm = {x: await createImageBitmap(canvas)};
+    const copy = await runner.structuredClone(bm);
+    compare_Object(enumerate_props(compare_ImageBitmap))(bm, copy);
+  },
+  requiresDocument: true
+});
+
+check('ObjectPrototype must lose its exotic-ness when cloned',
+  () => Object.prototype,
+  (copy, original) => {
+    assert_not_equals(copy, original);
+    assert_true(copy instanceof Object);
+
+    const newProto = { some: 'proto' };
+    // Must not throw:
+    Object.setPrototypeOf(copy, newProto);
+
+    assert_equals(Object.getPrototypeOf(copy), newProto);
+  }
+);
diff --git a/test/fixtures/wpt/html/webappapis/structured-clone/structured-clone.any.js b/test/fixtures/wpt/html/webappapis/structured-clone/structured-clone.any.js
new file mode 100644
index 00000000000000..34f96f33fdf881
--- /dev/null
+++ b/test/fixtures/wpt/html/webappapis/structured-clone/structured-clone.any.js
@@ -0,0 +1,9 @@
+// META: title=structuredClone() tests
+// META: script=/html/webappapis/structured-clone/structured-clone-battery-of-tests.js
+// META: script=/html/webappapis/structured-clone/structured-clone-battery-of-tests-with-transferables.js
+// META: script=/html/webappapis/structured-clone/structured-clone-battery-of-tests-harness.js
+
+runStructuredCloneBatteryOfTests({
+  structuredClone: (obj, transfer) => self.structuredClone(obj, { transfer }),
+  hasDocument: typeof document !== "undefined",
+});
diff --git a/test/fixtures/wpt/versions.json b/test/fixtures/wpt/versions.json
index 2eda2919ea9908..4ad5f68a33998b 100644
--- a/test/fixtures/wpt/versions.json
+++ b/test/fixtures/wpt/versions.json
@@ -31,6 +31,10 @@
     "commit": "2c5c3c4c27d27a419c1fdba3e9879c2d22037074",
     "path": "html/webappapis/microtask-queuing"
   },
+  "html/webappapis/structured-clone": {
+    "commit": "47d3fb280c9c632e684dee3b78ae1f4c5d5ba640",
+    "path": "html/webappapis/structured-clone"
+  },
   "html/webappapis/timers": {
     "commit": "5873f2d8f1f7bbb9c64689e52d04498614632906",
     "path": "html/webappapis/timers"
@@ -63,4 +67,4 @@
     "commit": "cdd0f03df41b222aed098fbbb11c6a3cc500a86b",
     "path": "WebCryptoAPI"
   }
-}
\ No newline at end of file
+}
diff --git a/test/parallel/test-bootstrap-modules.js b/test/parallel/test-bootstrap-modules.js
index 37cdbca3300368..79614cfa1107db 100644
--- a/test/parallel/test-bootstrap-modules.js
+++ b/test/parallel/test-bootstrap-modules.js
@@ -114,6 +114,7 @@ const expectedModules = new Set([
   'NativeModule internal/streams/transform',
   'NativeModule internal/streams/utils',
   'NativeModule internal/streams/writable',
+  'NativeModule internal/structured_clone',
   'NativeModule internal/timers',
   'NativeModule internal/url',
   'NativeModule internal/util',
diff --git a/test/parallel/test-global.js b/test/parallel/test-global.js
index dbd3b06d290d31..60df2c1d73f463 100644
--- a/test/parallel/test-global.js
+++ b/test/parallel/test-global.js
@@ -51,6 +51,7 @@ builtinModules.forEach((moduleName) => {
     'setImmediate',
     'setInterval',
     'setTimeout',
+    'structuredClone',
   ];
   assert.deepStrictEqual(new Set(Object.keys(global)), new Set(expected));
 }
diff --git a/test/parallel/test-structuredClone-global.js b/test/parallel/test-structuredClone-global.js
new file mode 100644
index 00000000000000..ae6120c04e0005
--- /dev/null
+++ b/test/parallel/test-structuredClone-global.js
@@ -0,0 +1,19 @@
+// Flags: --expose-internals
+'use strict';
+/* eslint-disable no-global-assign */
+
+require('../common');
+
+const {
+  structuredClone: _structuredClone
+} = require('internal/structured_clone');
+const {
+  strictEqual
+} = require('assert');
+
+strictEqual(globalThis.structuredClone, _structuredClone);
+structuredClone = undefined;
+strictEqual(globalThis.structuredClone, undefined);
+
+// Restore the value for the known globals check.
+structuredClone = _structuredClone;
diff --git a/test/wpt/status/html/webappapis/structured-clone.json b/test/wpt/status/html/webappapis/structured-clone.json
new file mode 100644
index 00000000000000..d2a7539641ffb5
--- /dev/null
+++ b/test/wpt/status/html/webappapis/structured-clone.json
@@ -0,0 +1,5 @@
+{
+  "structured-clone.any.js": {
+    "skip": "Missing File API"
+  }
+}
diff --git a/test/wpt/test-structured-clone.js b/test/wpt/test-structured-clone.js
new file mode 100644
index 00000000000000..98ef87184a6ce2
--- /dev/null
+++ b/test/wpt/test-structured-clone.js
@@ -0,0 +1,13 @@
+'use strict';
+
+require('../common');
+const { WPTRunner } = require('../common/wpt');
+
+const runner = new WPTRunner('html/webappapis/structured-clone');
+
+runner.setInitScript(`
+  const { Blob } = require('buffer');
+  global.Blob = Blob;
+`);
+
+runner.runJsTests();