From 00a8cee28dd861e91832501015f35f7fd4c753f3 Mon Sep 17 00:00:00 2001 From: Christina Conrad <114612268+cconrad8@users.noreply.github.com> Date: Tue, 17 Dec 2024 10:30:32 -0500 Subject: [PATCH 1/5] Update CellLineModel.yaml --- modules/Sample/CellLineModel.yaml | 6 ++++++ 1 file changed, 6 insertions(+) diff --git a/modules/Sample/CellLineModel.yaml b/modules/Sample/CellLineModel.yaml index b8ebf637..a21c3f5f 100644 --- a/modules/Sample/CellLineModel.yaml +++ b/modules/Sample/CellLineModel.yaml @@ -345,3 +345,9 @@ enums: HS05: description: 'NF2 schwannoma model' source: Sage Bionetworks + primary cultured fibroblast cell: + description: A primary cultured cell that is derived from fibroblast cell in vivo. + source: http://purl.obolibrary.org/obo/CLO_0037301 + + + From 204864a4c48877f788537eda437bdde934396a93 Mon Sep 17 00:00:00 2001 From: Christina Conrad <114612268+cconrad8@users.noreply.github.com> Date: Tue, 17 Dec 2024 10:36:17 -0500 Subject: [PATCH 2/5] Update MouseModel.yaml --- modules/Sample/MouseModel.yaml | 6 ++++++ 1 file changed, 6 insertions(+) diff --git a/modules/Sample/MouseModel.yaml b/modules/Sample/MouseModel.yaml index 3fcada4e..db71453b 100644 --- a/modules/Sample/MouseModel.yaml +++ b/modules/Sample/MouseModel.yaml @@ -1,6 +1,12 @@ enums: MouseModel: permissible_values: + Prss56Cre/+;Tom/+;Nf1fl/fl: + description: The Prss56Cre/+;Tom/+;Nf1fl/fl mouse model is genetically engineered to express Cre recombinase under the Prss56 promoter, enabling tissue-specific deletion of the Nf1 gene, alongside a visual reporter, Tomato fluorescent protein, for tracing Cre activity. + meaning: + Prss56Cre/+;Tom/+: + description: The Prss56Cre/+;Tom/+ mouse model is genetically engineered to express Cre recombinase under the Prss56 promoter, enabling tissue-specific gene modification, alongside a Tomato fluorescent protein reporter to visualize Cre activity. + meaning: B6;129S2-Trp53tm1Tyj Nf1tm1Tyj/J: description: '' meaning: https://www.jax.org/strain/008191 From effcc5f0488809de8909fd3441e6b915f266e0a1 Mon Sep 17 00:00:00 2001 From: Christina Conrad <114612268+cconrad8@users.noreply.github.com> Date: Tue, 17 Dec 2024 10:38:13 -0500 Subject: [PATCH 3/5] Update CellLineModel.yaml --- modules/Sample/CellLineModel.yaml | 2 +- 1 file changed, 1 insertion(+), 1 deletion(-) diff --git a/modules/Sample/CellLineModel.yaml b/modules/Sample/CellLineModel.yaml index a21c3f5f..87909a22 100644 --- a/modules/Sample/CellLineModel.yaml +++ b/modules/Sample/CellLineModel.yaml @@ -347,7 +347,7 @@ enums: source: Sage Bionetworks primary cultured fibroblast cell: description: A primary cultured cell that is derived from fibroblast cell in vivo. - source: http://purl.obolibrary.org/obo/CLO_0037301 + meaning: http://purl.obolibrary.org/obo/CLO_0037301 From 189d0d07d0b3f212628b9830a681c3bf87583886 Mon Sep 17 00:00:00 2001 From: Christina Conrad <114612268+cconrad8@users.noreply.github.com> Date: Tue, 17 Dec 2024 10:38:30 -0500 Subject: [PATCH 4/5] Update MouseModel.yaml --- modules/Sample/MouseModel.yaml | 2 -- 1 file changed, 2 deletions(-) diff --git a/modules/Sample/MouseModel.yaml b/modules/Sample/MouseModel.yaml index db71453b..d12d7f47 100644 --- a/modules/Sample/MouseModel.yaml +++ b/modules/Sample/MouseModel.yaml @@ -3,10 +3,8 @@ enums: permissible_values: Prss56Cre/+;Tom/+;Nf1fl/fl: description: The Prss56Cre/+;Tom/+;Nf1fl/fl mouse model is genetically engineered to express Cre recombinase under the Prss56 promoter, enabling tissue-specific deletion of the Nf1 gene, alongside a visual reporter, Tomato fluorescent protein, for tracing Cre activity. - meaning: Prss56Cre/+;Tom/+: description: The Prss56Cre/+;Tom/+ mouse model is genetically engineered to express Cre recombinase under the Prss56 promoter, enabling tissue-specific gene modification, alongside a Tomato fluorescent protein reporter to visualize Cre activity. - meaning: B6;129S2-Trp53tm1Tyj Nf1tm1Tyj/J: description: '' meaning: https://www.jax.org/strain/008191 From 023e503fc08b11eca83f0aaa217160f290a4f059 Mon Sep 17 00:00:00 2001 From: "nf-osi[bot]" Date: Tue, 17 Dec 2024 15:40:32 +0000 Subject: [PATCH 5/5] Rebuild NF.jsonld, json --- NF.jsonld | 60 +++++++++++++++++++++++++++++++++++++++++++++++++++++++ 1 file changed, 60 insertions(+) diff --git a/NF.jsonld b/NF.jsonld index 802c569b..03f3eaa1 100644 --- a/NF.jsonld +++ b/NF.jsonld @@ -21609,6 +21609,15 @@ { "@id": "bts:HS05" }, + { + "@id": "bts:Primaryculturedfibroblastcell" + }, + { + "@id": "bts:Prss56Cre/+;Tom/+;Nf1fl/fl" + }, + { + "@id": "bts:Prss56Cre/+;Tom/+" + }, { "@id": "bts:B6;129S2-Trp53tm1TyjNf1tm1Tyj/J" }, @@ -23982,6 +23991,57 @@ "sms:required": "sms:false", "sms:validationRules": [] }, + { + "@id": "bts:Primaryculturedfibroblastcell", + "@type": "rdfs:Class", + "rdfs:comment": "TBD", + "rdfs:label": "Primaryculturedfibroblastcell", + "rdfs:subClassOf": [ + { + "@id": "bts:ModelSystemName" + } + ], + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + }, + "sms:displayName": "primary cultured fibroblast cell", + "sms:required": "sms:false", + "sms:validationRules": [] + }, + { + "@id": "bts:Prss56Cre/+;Tom/+;Nf1fl/fl", + "@type": "rdfs:Class", + "rdfs:comment": "TBD", + "rdfs:label": "Prss56Cre/+;Tom/+;Nf1fl/fl", + "rdfs:subClassOf": [ + { + "@id": "bts:ModelSystemName" + } + ], + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + }, + "sms:displayName": "Prss56Cre/+;Tom/+;Nf1fl/fl", + "sms:required": "sms:false", + "sms:validationRules": [] + }, + { + "@id": "bts:Prss56Cre/+;Tom/+", + "@type": "rdfs:Class", + "rdfs:comment": "TBD", + "rdfs:label": "Prss56Cre/+;Tom/+", + "rdfs:subClassOf": [ + { + "@id": "bts:ModelSystemName" + } + ], + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + }, + "sms:displayName": "Prss56Cre/+;Tom/+", + "sms:required": "sms:false", + "sms:validationRules": [] + }, { "@id": "bts:B6;129S2-Trp53tm1TyjNf1tm1Tyj/J", "@type": "rdfs:Class",