diff --git a/packages/neuron-ui/src/components/NetworkEditor/index.tsx b/packages/neuron-ui/src/components/NetworkEditor/index.tsx
index 62d22e76e3..4105007a81 100644
--- a/packages/neuron-ui/src/components/NetworkEditor/index.tsx
+++ b/packages/neuron-ui/src/components/NetworkEditor/index.tsx
@@ -105,7 +105,7 @@ const NetworkEditor = () => {
             onChange={onChange}
             label={t('settings.network.edit-network.rpc-url')}
             error={editor.urlError}
-            placeholder="http://localhost:8114"
+            placeholder="http://127.0.0.1:8114"
             required
             autoFocus
           />
diff --git a/packages/neuron-ui/src/stories/NetworkSetting.stories.tsx b/packages/neuron-ui/src/stories/NetworkSetting.stories.tsx
index 75f24be4db..9dcafdbf23 100644
--- a/packages/neuron-ui/src/stories/NetworkSetting.stories.tsx
+++ b/packages/neuron-ui/src/stories/NetworkSetting.stories.tsx
@@ -10,7 +10,7 @@ const states: { [title: string]: State.Network[] } = {
     {
       id: 'Mainnet',
       name: 'Mainnet',
-      remote: 'http://localhost:8114',
+      remote: 'http://127.0.0.1:8114',
       chain: 'ckb',
       type: 0,
       genesisHash: '0x92b197aa1fba0f63633922c61c92375c9c074a93e85963554f5499fe1450d0e5',
@@ -18,7 +18,7 @@ const states: { [title: string]: State.Network[] } = {
     {
       id: 'Testnet',
       name: 'Testnet',
-      remote: 'http://localhost:8114',
+      remote: 'http://127.0.0.1:8114',
       chain: 'ckb_testnet',
       type: 1,
       genesisHash: '0x10639e0895502b5688a6be8cf69460d76541bfa4821629d86d62ba0aae3f9606',
@@ -26,7 +26,7 @@ const states: { [title: string]: State.Network[] } = {
     {
       id: 'Local',
       name: 'Local',
-      remote: 'http://localhost:8114',
+      remote: 'http://127.0.0.1:8114',
       chain: 'ckb_devnet',
       type: 1,
       genesisHash: '0x10639e0895502b5688a6be8cf69460d76541bfa4821629d86d62ba0aae3f9606',
diff --git a/packages/neuron-ui/src/stories/NetworkStatus.stories.tsx b/packages/neuron-ui/src/stories/NetworkStatus.stories.tsx
index 78655db6e2..40c32cf5bb 100644
--- a/packages/neuron-ui/src/stories/NetworkStatus.stories.tsx
+++ b/packages/neuron-ui/src/stories/NetworkStatus.stories.tsx
@@ -6,7 +6,7 @@ import NetworkStatus, { NetworkStatusProps } from 'components/NetworkStatus'
 const defaultProps: Omit<NetworkStatusProps, 'syncPercents' | 'syncBlockNumbers'> = {
   network: {
     name: 'network',
-    remote: 'http://localhost:3000',
+    remote: 'http://127.0.0.1:3000',
     type: 0,
     id: 'd',
     chain: 'ckb',
@@ -68,7 +68,7 @@ stories.add('With knobs', () => {
   const props = {
     network: {
       name: text('Network name', 'network name'),
-      remote: text('Remote', 'http://localhost:3000'),
+      remote: text('Remote', 'http://127.0.0.1:3000'),
       type: select('Type', [0, 1], 0) as any,
       id: text('id', 'd'),
       chain: select('Chain', ['ckb', 'ckb_testnet', 'ckb_dev'], 'ckb'),
diff --git a/packages/neuron-ui/src/tests/is/isMainnet/fixtures.ts b/packages/neuron-ui/src/tests/is/isMainnet/fixtures.ts
index d9fbc65adf..56dc338194 100644
--- a/packages/neuron-ui/src/tests/is/isMainnet/fixtures.ts
+++ b/packages/neuron-ui/src/tests/is/isMainnet/fixtures.ts
@@ -22,7 +22,7 @@ const fixtures = {
           chain: 'ckb',
           type: 0 as 0 | 1,
           name: 'Mainnet',
-          remote: 'http://localhost:8114',
+          remote: 'http://127.0.0.1:8114',
           genesisHash: '0x10639e0895502b5688a6be8cf69460d76541bfa4821629d86d62ba0aae3f9606',
         },
       ],
@@ -38,7 +38,7 @@ const fixtures = {
           chain: 'ckb_testnet',
           type: 0 as 0 | 1,
           name: 'Mainnet',
-          remote: 'http://localhost:8114',
+          remote: 'http://127.0.0.1:8114',
           genesisHash: '0x10639e0895502b5688a6be8cf69460d76541bfa4821629d86d62ba0aae3f9606',
         },
       ],
@@ -54,7 +54,7 @@ const fixtures = {
           chain: 'ckb',
           type: 0 as 0 | 1,
           name: 'Mainnet',
-          remote: 'http://localhost:8114',
+          remote: 'http://127.0.0.1:8114',
           genesisHash: '0x10639e0895502b5688a6be8cf69460d76541bfa4821629d86d62ba0aae3f9606',
         },
       ],
diff --git a/packages/neuron-wallet/src/services/networks.ts b/packages/neuron-wallet/src/services/networks.ts
index e185118094..5b9320679a 100644
--- a/packages/neuron-wallet/src/services/networks.ts
+++ b/packages/neuron-wallet/src/services/networks.ts
@@ -7,7 +7,7 @@ import { Validate, Required } from 'utils/validators'
 import { UsedName, NetworkNotFound, InvalidFormat } from 'exceptions'
 import { MAINNET_GENESIS_HASH, EMPTY_GENESIS_HASH, NetworkType, Network, TESTNET_GENESIS_HASH } from 'models/network'
 import CommonUtils from 'utils/common'
-import { BUNDLED_LIGHT_CKB_URL, LIGHT_CLIENT_TESTNET } from 'utils/const'
+import { BUNDLED_CKB_URL, BUNDLED_LIGHT_CKB_URL, LIGHT_CLIENT_TESTNET } from 'utils/const'
 import { generateRPC } from 'utils/ckb-rpc'
 
 const presetNetworks: { selected: string; networks: Network[] } = {
@@ -16,7 +16,7 @@ const presetNetworks: { selected: string; networks: Network[] } = {
     {
       id: 'mainnet',
       name: 'Default',
-      remote: 'http://localhost:8114',
+      remote: BUNDLED_CKB_URL,
       genesisHash: MAINNET_GENESIS_HASH,
       type: NetworkType.Default,
       chain: 'ckb'
@@ -66,6 +66,12 @@ export default class NetworksService extends Store {
 
   public getAll = () => {
     const networks = this.readSync<Network[]>(NetworksKey.List) || presetNetworks.networks
+    networks.forEach(network => {
+      // Currently, the RPC interface of the CKB node is bound to IPv4 by default.
+      // Starting from node17, its DNS resolution is no longer `ipv4first`.
+      // Therefore, to ensure normal connection to the ckb node, manual resolution needs to be done here.
+      network.remote = applyLocalhostIPv4Resolve(network.remote)
+    })
     const defaultNetwork = networks[0]
     const isOldDefaultName = ['Default', 'Mainnet'].includes(networks[0].name)
     defaultNetwork.name = isOldDefaultName ? 'default node' : defaultNetwork.name
@@ -195,3 +201,17 @@ export default class NetworksService extends Store {
     return network
   }
 }
+
+function applyLocalhostIPv4Resolve(url: string): string {
+  let urlObj
+  try {
+    urlObj = new URL(url)
+  } catch (err) {
+    return url
+  }
+
+  if (urlObj.hostname !== 'localhost') return url
+
+  urlObj.hostname = '127.0.0.1'
+  return urlObj.href
+}
diff --git a/packages/neuron-wallet/src/utils/const.ts b/packages/neuron-wallet/src/utils/const.ts
index 97401fb976..c4b6244f92 100644
--- a/packages/neuron-wallet/src/utils/const.ts
+++ b/packages/neuron-wallet/src/utils/const.ts
@@ -1,6 +1,6 @@
 export const MIN_PASSWORD_LENGTH = 8
 export const MAX_PASSWORD_LENGTH = 50
-export const BUNDLED_CKB_URL = 'http://localhost:8114'
+export const BUNDLED_CKB_URL = 'http://127.0.0.1:8114'
 export const BUNDLED_LIGHT_CKB_URL = 'http://127.0.0.1:9000'
 export const LIGHT_CLIENT_TESTNET = 'light_client_testnet'
 export const SETTINGS_WINDOW_TITLE = process.platform === 'darwin' ? 'settings.title.mac' : 'settings.title.normal'
diff --git a/packages/neuron-wallet/tests/controllers/export-debug.test.ts b/packages/neuron-wallet/tests/controllers/export-debug.test.ts
index 585a347659..e6676be488 100644
--- a/packages/neuron-wallet/tests/controllers/export-debug.test.ts
+++ b/packages/neuron-wallet/tests/controllers/export-debug.test.ts
@@ -55,7 +55,7 @@ jest.mock('../../src/services/networks', () => {
       return {
         getCurrent() {
           return {
-            remote: 'http://localhost:8114'
+            remote: 'http://127.0.0.1:8114'
           }
         }
       }
diff --git a/packages/neuron-wallet/tests/services/networks.test.ts b/packages/neuron-wallet/tests/services/networks.test.ts
index c0783f7d6e..204694e208 100644
--- a/packages/neuron-wallet/tests/services/networks.test.ts
+++ b/packages/neuron-wallet/tests/services/networks.test.ts
@@ -11,7 +11,7 @@ const ERROR_MESSAGE = {
 describe(`Unit tests of networks service`, () => {
   const newNetwork: Network = {
     name: `new network`,
-    remote: `http://localhost:8114`,
+    remote: `http://127.0.0.1:8114`,
     type: 0,
     genesisHash: '0x',
     id: '',
@@ -20,7 +20,7 @@ describe(`Unit tests of networks service`, () => {
 
   const newNetworkWithDefaultTypeOf1 = {
     name: `new network with the default type of 1`,
-    remote: `http://localhost:8114`,
+    remote: `http://127.0.0.1:8114`,
     id: '',
   }
 
@@ -82,12 +82,21 @@ describe(`Unit tests of networks service`, () => {
 
     it(`update the network' address`, async () => {
       const network = await service.create(newNetworkWithDefaultTypeOf1.name, newNetworkWithDefaultTypeOf1.remote)
-      const address = `http://localhost:8115`
+      const address = `http://127.0.0.1:8115`
       await service.update(network.id, { remote: address })
       const updated = service.get(network.id)
       expect(updated && updated.remote).toBe(address)
     })
 
+    it(`use ipv4 to resolve the localhost in network' remote`, async () => {
+      const network = await service.create(newNetworkWithDefaultTypeOf1.name, 'http://localhost:8114/')
+      const created = service.get(network.id)
+      expect(created && created.remote).toBe('http://127.0.0.1:8114/')
+      await service.update(network.id, { remote: 'http://localhost:8114/' })
+      const updated = service.get(network.id)
+      expect(updated && updated.remote).toBe('http://127.0.0.1:8114/')
+    })
+
     it(`set the network to be the current one`, async () => {
       const network = await service.create(newNetworkWithDefaultTypeOf1.name, newNetworkWithDefaultTypeOf1.remote)
       await service.activate(network.id)
@@ -151,11 +160,11 @@ describe(`Unit tests of networks service`, () => {
 
   describe(`validation on network existence`, () => {
     beforeEach(async () => {
-      await service.create('Default', 'http://localhost:8114')
+      await service.create('Default', 'http://127.0.0.1:8114')
     });
 
     it(`create network with existing name of Default`, () => {
-      expect(service.create('Default', 'http://localhost:8114')).rejects.toThrowError(t(ERROR_MESSAGE.NAME_USED))
+      expect(service.create('Default', 'http://127.0.0.1:8114')).rejects.toThrowError(t(ERROR_MESSAGE.NAME_USED))
     })
 
     it(`update network which is not existing`, () => {
diff --git a/packages/neuron-wallet/tests/services/node.test.ts b/packages/neuron-wallet/tests/services/node.test.ts
index 4c80e11d9d..5adf57f0e4 100644
--- a/packages/neuron-wallet/tests/services/node.test.ts
+++ b/packages/neuron-wallet/tests/services/node.test.ts
@@ -329,7 +329,7 @@ describe('NodeService', () => {
       expect(stubbedTipNumberSubjectCallback).toHaveBeenCalledWith('0')
     })
     describe('targets to bundled node', () => {
-      const bundledNodeUrl = 'http://localhost:8114'
+      const bundledNodeUrl = 'http://127.0.0.1:8114'
       beforeEach(async () => {
         stubbedCKBSetNode.mockImplementation(() => {
           nodeService.ckb.node.url = bundledNodeUrl