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Eliminate BBMap from pipeline #128

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willbradshaw opened this issue Dec 17, 2024 · 0 comments
Open

Eliminate BBMap from pipeline #128

willbradshaw opened this issue Dec 17, 2024 · 0 comments
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enhancement New feature or request priority_2 time&cost Changes to improve the pipeline's runtime and computational cost

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@willbradshaw
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Especially in recent runs, using BBMap to identify viral false-positives arising from contamination seems to significantly increase the runtime and computational cost of the pipeline. We should be able to replace it, either with another aligner or by modifying the configuration of Bowtie2 (which is used for the same purpose but seems to detect a different set of false positives). However, this will require careful QC to check that we're not introducing new false positives into the final pipeline output.

@willbradshaw willbradshaw added enhancement New feature or request priority_2 labels Dec 17, 2024
@willbradshaw willbradshaw added the time&cost Changes to improve the pipeline's runtime and computational cost label Dec 17, 2024
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Labels
enhancement New feature or request priority_2 time&cost Changes to improve the pipeline's runtime and computational cost
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