diff --git a/contrib/depends/hosts/darwin.mk b/contrib/depends/hosts/darwin.mk
index 58ff5dc32c..cea4f74305 100644
--- a/contrib/depends/hosts/darwin.mk
+++ b/contrib/depends/hosts/darwin.mk
@@ -2,14 +2,26 @@ OSX_MIN_VERSION=10.13
 OSX_SDK_VERSION=11.0
 XCODE_VERSION=12.2
 XCODE_BUILD_ID=12B45b
-LD64_VERSION=609
+LD64_VERSION=711
 
 OSX_SDK=$(host_prefix)/native/SDK
 
-darwin_native_toolchain=darwin_sdk native_cctools
+darwin_native_toolchain=darwin_sdk
 
-clang_prog=$(shell $(SHELL) $(.SHELLFLAGS) "command -v clang")
-clangxx_prog=$(shell $(SHELL) $(.SHELLFLAGS) "command -v clang++")
+
+clang_prog=clang
+clangxx_prog=clang++
+llvm_config_prog=llvm-config
+
+llvm_lib_dir=$(shell $(llvm_config_prog) --libdir)
+
+darwin_AR=llvm-ar
+darwin_DSYMUTIL=dsymutil
+darwin_NM=llvm-nm
+darwin_OBJDUMP=llvm-objdump
+darwin_RANLIB=llvm-ranlib
+darwin_STRIP=llvm-strip
+darwin_LIBTOOL=llvm-libtool-darwin
 
 # Flag explanations:
 #
@@ -37,23 +49,23 @@ clangxx_prog=$(shell $(SHELL) $(.SHELLFLAGS) "command -v clang++")
 darwin_CC=env -u C_INCLUDE_PATH -u CPLUS_INCLUDE_PATH \
               -u OBJC_INCLUDE_PATH -u OBJCPLUS_INCLUDE_PATH -u CPATH \
               -u LIBRARY_PATH \
-            $(clang_prog) --target=$(host) -mmacosx-version-min=$(OSX_MIN_VERSION) \
-              -B$(build_prefix)/bin -mlinker-version=$(LD64_VERSION) \
-              -isysroot$(OSX_SDK) \
+            $(clang_prog) --target=$(host) \
+              -B$(build_prefix)/bin \
               -isysroot$(OSX_SDK) -nostdlibinc \
               -iwithsysroot/usr/include -iframeworkwithsysroot/System/Library/Frameworks
 
 darwin_CXX=env -u C_INCLUDE_PATH -u CPLUS_INCLUDE_PATH \
                -u OBJC_INCLUDE_PATH -u OBJCPLUS_INCLUDE_PATH -u CPATH \
                -u LIBRARY_PATH \
-             $(clangxx_prog) --target=$(host) -mmacosx-version-min=$(OSX_MIN_VERSION) \
-               -B$(build_prefix)/bin -mlinker-version=$(LD64_VERSION) \
+             $(clangxx_prog) --target=$(host) \
+               -B$(build_prefix)/bin \
                -isysroot$(OSX_SDK) -nostdlibinc \
                -iwithsysroot/usr/include/c++/v1 \
                -iwithsysroot/usr/include -iframeworkwithsysroot/System/Library/Frameworks
 
-darwin_CFLAGS=-pipe
-darwin_CXXFLAGS=$(darwin_CFLAGS)
+darwin_CFLAGS=-pipe -mmacosx-version-min=$(OSX_MIN_VERSION) -mlinker-version=$(LD64_VERSION)
+darwin_CXXFLAGS=-pipe -mmacosx-version-min=$(OSX_MIN_VERSION) -mlinker-version=$(LD64_VERSION)
+darwin_LDFLAGS=-Wl,-platform_version,macos,$(OSX_MIN_VERSION),$(OSX_SDK_VERSION) -Wl,-no_adhoc_codesign -fuse-ld=lld
 darwin_ARFLAGS=cr
 
 darwin_release_CFLAGS=-O2
diff --git a/contrib/depends/packages/libusb.mk b/contrib/depends/packages/libusb.mk
index 53c91134c8..a4b24f8263 100644
--- a/contrib/depends/packages/libusb.mk
+++ b/contrib/depends/packages/libusb.mk
@@ -3,8 +3,10 @@ $(package)_version=1.0.27
 $(package)_download_path=https://github.com/libusb/libusb/releases/download/v$($(package)_version)
 $(package)_file_name=$(package)-$($(package)_version).tar.bz2
 $(package)_sha256_hash=ffaa41d741a8a3bee244ac8e54a72ea05bf2879663c098c82fc5757853441575
+$(package)_patches=fix-c11-check.patch
 
 define $(package)_preprocess_cmds
+  patch -p1 < $($(package)_patch_dir)/fix-c11-check.patch && \
   cp -f $(BASEDIR)/config.guess $(BASEDIR)/config.sub . && \
   autoreconf -i
 endef
diff --git a/contrib/depends/packages/native_cctools.mk b/contrib/depends/packages/native_cctools.mk
deleted file mode 100644
index a019b1649e..0000000000
--- a/contrib/depends/packages/native_cctools.mk
+++ /dev/null
@@ -1,37 +0,0 @@
-package=native_cctools
-$(package)_version=04663295d0425abfac90a42440a7ec02d7155fea
-$(package)_download_path=https://github.com/tpoechtrager/cctools-port/archive
-$(package)_download_file=$($(package)_version).tar.gz
-$(package)_file_name=$(package)-$($(package)_version).tar.gz
-$(package)_sha256_hash=70a7189418c2086d20c299c5d59250cf5940782c778892ccc899c66516ed240e
-$(package)_build_subdir=cctools
-$(package)_patches=no-build-date.patch
-$(package)_dependencies=native_libtapi
-
-define $(package)_set_vars
-$(package)_config_opts=--target=$(host) --disable-lto-support --with-libtapi=$(host_prefix)
-$(package)_ldflags+=-Wl,-rpath=\\$$$$$$$$\$$$$$$$$ORIGIN/../lib
-$(package)_cc=$(clang_prog)
-$(package)_cxx=$(clangxx_prog)
-endef
-
-define $(package)_preprocess_cmds
-  cp -f $(BASEDIR)/config.guess $(BASEDIR)/config.sub cctools
-endef
-
-define $(package)_preprocess_cmds
-  patch -p1 < $($(package)_patch_dir)/no-build-date.patch
-endef
-
-define $(package)_config_cmds
-  $($(package)_autoconf)
-endef
-
-define $(package)_build_cmds
-  $(MAKE)
-endef
-
-define $(package)_stage_cmds
-  $(MAKE) DESTDIR=$($(package)_staging_dir) install && \
-  cp $($(package)_extract_dir)/cctools/misc/install_name_tool $($(package)_staging_prefix_dir)/bin/
-endef
diff --git a/contrib/depends/packages/native_libtapi.mk b/contrib/depends/packages/native_libtapi.mk
deleted file mode 100644
index 36234a001c..0000000000
--- a/contrib/depends/packages/native_libtapi.mk
+++ /dev/null
@@ -1,19 +0,0 @@
-package=native_libtapi
-$(package)_version=664b8414f89612f2dfd35a9b679c345aa5389026
-$(package)_download_path=https://github.com/tpoechtrager/apple-libtapi/archive
-$(package)_download_file=$($(package)_version).tar.gz
-$(package)_file_name=$(package)-$($(package)_version).tar.gz
-$(package)_sha256_hash=62e419c12d1c9fad67cc1cd523132bc00db050998337c734c15bc8d73cc02b61
-$(package)_patches=no_embed_git_rev.patch
-
-define $(package)_preprocess_cmds
-  patch -p1 -i $($(package)_patch_dir)/no_embed_git_rev.patch
-endef
-
-define $(package)_build_cmds
-  CC=$(clang_prog) CXX=$(clangxx_prog) INSTALLPREFIX=$($(package)_staging_prefix_dir) ./build.sh
-endef
-
-define $(package)_stage_cmds
-  ./install.sh
-endef
diff --git a/contrib/depends/packages/packages.mk b/contrib/depends/packages/packages.mk
index cb4e8e228a..68935608b9 100644
--- a/contrib/depends/packages/packages.mk
+++ b/contrib/depends/packages/packages.mk
@@ -24,5 +24,5 @@ mingw32_packages = $(hardware_packages)
 mingw32_native_packages = $(hardware_native_packages)
 
 ifneq ($(build_os),darwin)
-darwin_native_packages += darwin_sdk native_cctools native_libtapi
+darwin_native_packages += darwin_sdk
 endif
diff --git a/contrib/depends/packages/zeromq.mk b/contrib/depends/packages/zeromq.mk
index 669d06d839..106b5678ec 100644
--- a/contrib/depends/packages/zeromq.mk
+++ b/contrib/depends/packages/zeromq.mk
@@ -8,7 +8,6 @@ define $(package)_set_vars
   $(package)_config_opts=--without-documentation --disable-shared --without-libsodium --disable-curve
   $(package)_config_opts_linux=--with-pic
   $(package)_config_opts_freebsd=--with-pic
-  $(package)_cxxflags=-std=c++11
 endef
 
 define $(package)_config_cmds
diff --git a/contrib/depends/patches/libusb/fix-c11-check.patch b/contrib/depends/patches/libusb/fix-c11-check.patch
new file mode 100644
index 0000000000..93b005763e
--- /dev/null
+++ b/contrib/depends/patches/libusb/fix-c11-check.patch
@@ -0,0 +1,22 @@
+diff --git a/configure.ac b/configure.ac
+index 6dc7c698..eebe10a1 100644
+--- a/configure.ac
++++ b/configure.ac
+@@ -46,7 +46,7 @@ dnl note that we don't just check if the compiler accepts '-std=x11'
+ dnl but also that it supports the _Thread_local keyword because some compilers
+ dnl (e.g. gcc 4.8) accept the command line option but do not implement TLS
+ saved_CFLAGS="${CFLAGS}"
+-CFLAGS="-std=gnu11"
++CFLAGS="${saved_CFLAGS} -std=gnu11"
+ AC_MSG_CHECKING([if $CC supports -std=gnu11])
+ AC_COMPILE_IFELSE([AC_LANG_PROGRAM([_Thread_local int x;], [x = 42;])],
+ 	[AC_MSG_RESULT([yes])
+@@ -55,7 +55,7 @@ AC_COMPILE_IFELSE([AC_LANG_PROGRAM([_Thread_local int x;], [x = 42;])],
+ 	 c_dialect=])
+ if test "x$c_dialect" != xgnu; then
+ 	dnl fallback check for -std=c11 compiler support (required)
+-	CFLAGS="-std=c11"
++	CFLAGS="${saved_CFLAGS} -std=c11"
+ 	AC_MSG_CHECKING([if $CC supports -std=c11])
+ 	AC_COMPILE_IFELSE([AC_LANG_PROGRAM([_Thread_local int x;], [x = 42;])],
+ 		[AC_MSG_RESULT([yes])],
diff --git a/contrib/depends/patches/native_cctools/no-build-date.patch b/contrib/depends/patches/native_cctools/no-build-date.patch
deleted file mode 100644
index 8b7d1e1f76..0000000000
--- a/contrib/depends/patches/native_cctools/no-build-date.patch
+++ /dev/null
@@ -1,12 +0,0 @@
-diff --git a/cctools/ld64/src/ld/Options.cpp b/cctools/ld64/src/ld/Options.cpp
-index 3bb8324..033760d 100644
---- a/cctools/ld64/src/ld/Options.cpp
-+++ b/cctools/ld64/src/ld/Options.cpp
-@@ -4279,7 +4279,6 @@ void Options::buildSearchPaths(int argc, const char* argv[])
- 			fVerbose = true;
- 			extern const char ldVersionString[];
- 			fprintf(stderr, "%s", ldVersionString);
--			fprintf(stderr, "BUILD "  __TIME__ " "  __DATE__"\n");
- 			fprintf(stderr, "configured to support archs: %s\n", ALL_SUPPORTED_ARCHS);
- 			 // if only -v specified, exit cleanly
- 			 if ( argc == 2 ) {
diff --git a/contrib/depends/patches/native_libtapi/no_embed_git_rev.patch b/contrib/depends/patches/native_libtapi/no_embed_git_rev.patch
deleted file mode 100644
index b898ccb43f..0000000000
--- a/contrib/depends/patches/native_libtapi/no_embed_git_rev.patch
+++ /dev/null
@@ -1,31 +0,0 @@
-diff --git a/src/llvm/CMakeLists.txt b/src/llvm/CMakeLists.txt
-index ab92717c8..4ad621ea3 100644
---- a/src/llvm/CMakeLists.txt
-+++ b/src/llvm/CMakeLists.txt
-@@ -752,9 +752,10 @@ set(LLVM_SRPM_USER_BINARY_SPECFILE ${CMAKE_CURRENT_SOURCE_DIR}/llvm.spec.in
- set(LLVM_SRPM_BINARY_SPECFILE ${CMAKE_CURRENT_BINARY_DIR}/llvm.spec)
- set(LLVM_SRPM_DIR "${CMAKE_CURRENT_BINARY_DIR}/srpm")
- 
--# SVN_REVISION and GIT_COMMIT get set by the call to add_version_info_from_vcs.
--# DUMMY_VAR contains a version string which we don't care about.
--add_version_info_from_vcs(DUMMY_VAR)
-+# A call to add_version_info_from_vcs() was removed, leaving SVN_REVISION
-+# and GIT_COMMIT unset. Accordingly, LLVM_RPM_SPEC_REVISION is left empty.
-+# This variable appears to be unused. Since it may be used in a future
-+# update of native_libtapi this change serves as a precautionairy measure.
- if ( SVN_REVISION )
-   set(LLVM_RPM_SPEC_REVISION "r${SVN_REVISION}")
- elseif ( GIT_COMMIT )
-diff --git a/src/llvm/cmake/modules/GenerateVersionFromCVS.cmake b/src/llvm/cmake/modules/GenerateVersionFromCVS.cmake
-index 6b1c71983..e16326ed6 100644
---- a/src/llvm/cmake/modules/GenerateVersionFromCVS.cmake
-+++ b/src/llvm/cmake/modules/GenerateVersionFromCVS.cmake
-@@ -24,7 +24,7 @@ include(VersionFromVCS)
- set(ENV{TERM} "dumb")
- 
- function(append_info name path)
--  add_version_info_from_vcs(REVISION ${path})
-+  set(REVISION "git-0000000")
-   string(STRIP "${REVISION}" REVISION)
-   file(APPEND "${HEADER_FILE}.txt"
-     "#define ${name} \"${REVISION}\"\n")
diff --git a/contrib/depends/toolchain.cmake.in b/contrib/depends/toolchain.cmake.in
index f5a7264e3e..da3922ebe2 100644
--- a/contrib/depends/toolchain.cmake.in
+++ b/contrib/depends/toolchain.cmake.in
@@ -80,12 +80,16 @@ if(CMAKE_SYSTEM_NAME STREQUAL "Darwin")
   SET(_CMAKE_TOOLCHAIN_PREFIX @prefix@/native/bin/${CONF_TRIPLE}-)
   SET(CMAKE_C_COMPILER @CC@)
   SET(CMAKE_C_COMPILER_TARGET ${CLANG_TARGET})
-  SET(CMAKE_C_FLAGS_INIT -B${_CMAKE_TOOLCHAIN_PREFIX})
+  SET(CMAKE_C_FLAGS "@CFLAGS@")
   SET(CMAKE_CXX_COMPILER @CXX@ -stdlib=libc++)
   SET(CMAKE_CXX_COMPILER_TARGET ${CLANG_TARGET})
-  SET(CMAKE_CXX_FLAGS_INIT -B${_CMAKE_TOOLCHAIN_PREFIX})
+  SET(CMAKE_CXX_FLAGS "@CXXFLAGS@")
+  set(CMAKE_EXE_LINKER_FLAGS "@LDFLAGS@")
+  set(CMAKE_MODULE_LINKER_FLAGS "@LDFLAGS@")
+  set(CMAKE_SHARED_LINKER_FLAGS "@LDFLAGS@")
+  set(CMAKE_INSTALL_NAME_TOOL llvm-install-name-tool)
   SET(CMAKE_ASM_COMPILER clang)
-  SET(CMAKE_ASM-ATT_COMPILER as)
+  SET(CMAKE_ASM-ATT_COMPILER llvm-as)
   SET(CMAKE_ASM_COMPILER_TARGET ${CLANG_TARGET})
   SET(CMAKE_ASM-ATT_COMPILER_TARGET ${CLANG_TARGET})
   SET(APPLE True)
@@ -95,8 +99,6 @@ if(CMAKE_SYSTEM_NAME STREQUAL "Darwin")
   SET(CMAKE_OSX_SYSROOT "@prefix@/native/SDK/")
   SET(CMAKE_OSX_DEPLOYMENT_TARGET "10.13")
   SET(CMAKE_CXX_STANDARD 17)
-  SET(LLVM_ENABLE_PIC OFF)
-  SET(LLVM_ENABLE_PIE OFF)
 elseif(CMAKE_SYSTEM_NAME STREQUAL "Android")
   SET(ANDROID TRUE)
   if(ARCHITECTURE STREQUAL "arm")
diff --git a/contrib/guix/libexec/build.sh b/contrib/guix/libexec/build.sh
index 63b88bcee0..cb08e6e54b 100644
--- a/contrib/guix/libexec/build.sh
+++ b/contrib/guix/libexec/build.sh
@@ -164,20 +164,7 @@ for p in "${PATHS[@]}"; do
 done
 
 # Disable Guix ld auto-rpath behavior
-case "$HOST" in
-    *darwin*)
-        # The auto-rpath behavior is necessary for darwin builds as some native
-        # tools built by depends refer to and depend on Guix-built native
-        # libraries
-        #
-        # After the native packages in depends are built, the ld wrapper should
-        # no longer affect our build, as clang would instead reach for
-        # x86_64-apple-darwin-ld from cctools
-        ;;
-    *android*)
-        ;;
-    *) export GUIX_LD_WRAPPER_DISABLE_RPATH=yes ;;
-esac
+export GUIX_LD_WRAPPER_DISABLE_RPATH=yes
 
 # Make /usr/bin if it doesn't exist
 [ -e /usr/bin ] || mkdir -p /usr/bin
@@ -220,16 +207,6 @@ export GLIBC_DYNAMIC_LINKER=${glibc_dynamic_linker}
 # Environment variables for determinism
 export TAR_OPTIONS="--owner=0 --group=0 --numeric-owner --mtime='@${SOURCE_DATE_EPOCH}' --sort=name"
 export TZ="UTC"
-case "$HOST" in
-    *darwin*)
-        # cctools AR, unlike GNU binutils AR, does not have a deterministic mode
-        # or a configure flag to enable determinism by default, it only
-        # understands if this env-var is set or not. See:
-        #
-        # https://github.com/tpoechtrager/cctools-port/blob/55562e4073dea0fbfd0b20e0bf69ffe6390c7f97/cctools/ar/archive.c#L334
-        export ZERO_AR_DATE=yes
-        ;;
-esac
 
 ####################
 # Depends Building #
diff --git a/contrib/guix/manifest.scm b/contrib/guix/manifest.scm
index 247531d4ca..a76a7c9cde 100644
--- a/contrib/guix/manifest.scm
+++ b/contrib/guix/manifest.scm
@@ -308,6 +308,7 @@ chain for " target " development."))
           ((string-contains target "darwin")
            (list
              gcc-toolchain-10
-             clang-toolchain-11
-             binutils))
+             clang-toolchain-17
+             lld-17
+             (make-lld-wrapper lld-17 #:lld-as-ld? #t)))
           (else '())))))