diff --git a/.github/workflows/codeql-analysis.yml b/.github/workflows/codeql-analysis.yml
new file mode 100644
index 0000000000..8f34c0a4fa
--- /dev/null
+++ b/.github/workflows/codeql-analysis.yml
@@ -0,0 +1,54 @@
+name: "CodeQL"
+
+on:
+  push:
+    branches: [ main ]
+  pull_request:
+    branches: [ main ]
+  schedule:
+    - cron: '0 0 * * 0'
+
+jobs:
+  analyze:
+    name: Analyze
+    runs-on: ubuntu-latest
+
+    strategy:
+      fail-fast: false
+      matrix:
+        language: [ 'csharp', 'javascript' ]
+
+    steps:
+    - name: Checkout repository
+      uses: actions/checkout@v2
+
+    - name: Setup dotnet (for SQL generation)
+      uses: actions/setup-dotnet@v1
+      if: ${{ matrix.language == 'csharp' }}
+      with:
+        dotnet-version: '3.1.401'
+
+    - name: Setup dotnet (based on Global config)
+      uses: actions/setup-dotnet@v1
+      if: ${{ matrix.language == 'csharp' }}
+
+    # Initializes the CodeQL tools for scanning.
+    - name: Initialize CodeQL
+      uses: github/codeql-action/init@v1
+      with:
+        languages: ${{ matrix.language }}
+        # If you wish to specify custom queries, you can do so here or in a config file.
+        # By default, queries listed here will override any specified in a config file.
+        # Prefix the list here with "+" to use these queries and those in the config file.
+        # queries: ./path/to/local/query, your-org/your-repo/queries@main
+
+    # Build C# solutions manually
+    - name: dotnet build
+      run: |
+        dotnet build Microsoft.Health.Dicom.sln -c Release -p:ContinuousIntegrationBuild=true
+        dotnet build converter/dicom-cast/Microsoft.Health.DicomCast.sln -c Release -p:ContinuousIntegrationBuild=true
+        dotnet build tools/scale-testing/ScaleTesting.sln -c Release -p:ContinuousIntegrationBuild=true
+      if: ${{ matrix.language == 'csharp' }}
+
+    - name: Perform CodeQL Analysis
+      uses: github/codeql-action/analyze@v1