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+ + + + + + + blood vessel layer + + + + + + + + + respiratory system epithelium + + + + + + + + + gastrointestinal system epithelium + + + + + + + + + + vasculature of retina + + + + + + + + + splanchnic layer of lateral plate mesoderm + + + + + + + + + + + urogenital sinus epithelium + + + + + + + + + articulation + + + + + + + + + + ectodermal part of digestive tract + + + + + + + + + + epithelium of gonad + + + + + + + + + subdivision of digestive tract + + + + + + + + + organ component layer + + + + + + + + + immune organ + + + + + + + + + neural groove + + + + + + + + + + + + + neural fold + + + + + + + + + neural rod + + + + + + + + + + ectodermal placode + + + + + + + + + muscle structure + + + + + + + + + reproductive structure + + + + + + + + + epithelial fold + + + + + + + + + multi cell part structure + + + + + + + + + trunk region element + + + + + + + + + + thoracic cavity element + + + + + + + + + thoracic segment organ + + + + + + + + + + head mesenchyme + + + + + + + + + + trunk mesenchyme + + + + + + + + + + ventricular system of central nervous system + + + + + + + + + + ventricular system of brain + + + + + + + + + tela choroidea + + + + + + + + + + + tela choroidea of telencephalic ventricle + + + + + + + + + embryonic tissue + + + + + + + + + extraembryonic tissue + + + + + + + + + ventricle of nervous system + + + + + + + + + photoreceptor array + + + + + + + + + transparent eye structure + + + + + + + + + alimentary part of gastrointestinal system + + + + + + + + + developing anatomical structure + + + + + + + + + + lens vesicle + + + + + + + + + + primitive heart tube + + + + + + + + + gonad primordium + + + + + + + + + trunk somite + + + + + + + + + + vascular plexus + + + + + + + + + anterior chamber epithelium + + + + + + + + + lens vesicle epithelium + + + + + + + + + bone foramen + + + + + + + + + acellular membrane + + + + + + + + + basement membrane of epithelium + + + + + + + + + + developing mesenchymal condensation + + + + + + + + + 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+ + + + + + + shell + + + + + + + + + vasculature of organ + + + + + + + + + + head mesenchyme from mesoderm + + + + + + + + + + mandibular process mesenchyme + + + + + + + + + vascular cord + + + + + + + + + + cardiogenic splanchnic mesoderm + + + + + + + + + cleaving embryo + + + + + + + + + presumptive gut + + + + + + + + + mandibular neural crest + + + + + + + + + primary circulatory organ + + + + + + + + + meconium + + + + + + + + + neural keel + + + + + + + + + + mesenchyme derived from head neural crest + + + + + + + + + 1st arch mandibular component + + + + + + + + + + nuclear complex of neuraxis + + + + + + + + + presumptive segmental plate + + + + + + + + + presumptive neural plate + + + + + + + + + presumptive paraxial mesoderm + + + + + + + + + + outer epithelium + + + + + + + + + + + enveloping layer of ectoderm + + + + + + + + + epithelial tube open at both ends + + + + + + + + + epithelial vesicle + + + + + + + + + dense mesenchyme tissue + + + + + + + + + migrating mesenchyme population + + + + + + + + + pigment epithelium of eye + + + + + + + + + anatomical junction + + + + + + + + + + anlage + + + + + + + + + + bone of reproductive organ + + + + + + + + + transudate + + + + + + + + + + secretion of serous gland + + + + + + + + + vascular system + + + + + + + + + craniocervical region + + + + + + + + + appendage girdle region + + + + + + + + + girdle bone/zone + + + + + + + + + + pectoral girdle bone + + + + + + + + + pectoral girdle skeleton + + + + + + + + + bone of craniocervical region + + + + + + + + + joint of girdle + + + + + + + + + craniocervical region musculature + + + + + + + + + pharyngeal arch system + + + + + + + + + embryonic head + + + + + + + + + + neural tube derived brain + + + + + + + + + + vasculature of brain + + + + + + + + + entire embryonic mesenchyme + + + + + + + + + pharyngeal region of foregut + + + + + + + + + axilla + + + + + + + + + ectoderm of buccopharyngeal membrane + + + + + + + + + endoderm of buccopharyngeal membrane + + + + + + + + + + + pharyngeal arch mesenchymal region + + + + + + + + + mesenchyme of hindgut + + + + + + + + + + anal membrane endodermal component + + + + + + + + + subdivision of trunk + + + + + + + + + 1st arch mandibular mesenchyme + + + + + + + + + forebrain neural plate + + + + + + + + + trunk paraxial mesoderm + + + + + + + + + + telencephalic nucleus + + + + + + + + + early telencephalic vesicle + + + + + + + + + + cardiac mesenchyme + + + + + + + + + + + embryonic cloacal epithelium + + + + + + + + + + anterior lateral plate mesoderm + + + + + + + + + facial mesenchyme + + + + + + + + + + optic neural crest + + + + + + + + + multicellular anatomical structure + + + + + + + + + 1st arch mesenchyme + + + + + + + + + + + entire pharyngeal arch associated mesenchyme + + + + + + + + + open anatomical space + + + + + + + + + cuboidal epithelium + + + + + + + + + future dermis + + + + + + + + + protuberance + + + + + + + + + + thalamic complex + + + + + + 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ecto-epithelium + + + + + + + + + + ciliary processes + + + + + + + + + + appendage girdle complex + + + + + + + + + pectoral complex + + + + + + + + + girdle skeleton + + + + + + + + + bone of appendage girdle complex + + + + + + + + + bone of pectoral complex + + + + + + + + + subdivision of skeleton + + + + + + + + + + synovial joint of pectoral girdle + + + + + + + + + nonsynovial joint + + + + + + + + + + axial skeletal system + + + + + + + + + postcranial axial skeletal system + + + + + + + + + + facial skeleton + + + + + + + + + primary subdivision of skull + + + + + + + + + + central nervous system cell part cluster + + + + + + + + + organ system subdivision + + + + + + + + + + intra-ocular muscle + + + + + + + + + appendicular skeletal system + + + + + + + + + + embryonic skin basal layer + + + + + + + + + + gray matter of telencephalon + + + + + + + + + + cranial blood vasculature + + + + + + + + + + cranial lymph vasculature + + + + + + + + + cell condensation + + + + + + + + + + + jaw region + + + + + + + + + + + oral epithelium from ectoderm + + + + + + + + + subdivision of organism along main body axis + + + + + + + + + embryonic cardiovascular system + + + + + + + + + nerve of head region + + + + + + + + + non-neurogenic ectodermal placode + + + + + + + + + irregular connective tissue + + + + + + + + + + dense irregular connective tissue + + + + + + + + + + dense connective tissue + + + + + + + + + loose connective tissue + + + + + + + + + collection of collagen fibrils + + + + + + + + + bone collagen fibril + + + + + + + + + + + anterior uvea + + + + + + + + + ingested food + + + + + + + + + head or neck skin + + + + + + + + + columnar epithelium + + + + + + + + + + meso-epithelium + + + + + + + + + embryonic facial prominence + + + + + + + + + + bone of jaw + + + + + + + + + internal anal region + + + + + + + + + cloacal vent + + + + + + + + + extraembryonic cavity + + + + + + + + + skeleton of pectoral complex + + + + + + + + + cloacal mucosa + + + + + + + + + + cloacal epithelium + + + + + + + + + future brain vesicle + + + + + + + + + subdivision of tube + + + + + + + + + foramen of skull + + + + + + + + + anatomical conduit space + + + + + + + + + main body axis + + + + + + + + + body proper + + + + + + + + + + integumentary projection + + + + + + + + + integumentary system layer + + + + + + + + + digestive system element + + + + + + + + + future telencephalon + + + + + + + + + + mesenchyme derived from neural crest + + + + + + + + + thoracic skeleton + + + + + + + + + + anal membrane ectodermal component + + + + + + + + + prosomere + + + + + + + + + + cloacal muscle + + + + + + + + + musculature of pectoral complex + + + + + + + + + primordial vasculature + + + + + + + + + non-connected functional system + + + + + + + + + lateral structure + + + + + + + + + circulatory organ + + + + + + + + + respiratory system basement membrane + + + + + + + + + heart plus pericardium + + + + + + + + + axilla skin + + + + + + + + + smooth muscle layer in fatty layer of subcutaneous tissue + + + + + + + + + + eye epithelium + + + + + + + + + foregut epithelium + + + + + + + + + future central nervous system + + + + + + + + + future nervous system + + + + + + + + + entire extraembryonic component + + + + + + + + + transitional anatomical structure + + + + + + + + + developing mesenchymal structure + + + + + + + + + + heart vasculature + + + + + + + + + + reproductive system mucosa + + + + + + + + + skin epithelium + + + + + + + + + + + + chorioretinal region + + + + + + + + + gray matter of forebrain + + + + + + + + + gray matter of diencephalon + + + + + + + + + sensory organ epithelium + + + + + + + + + morphological feature + + + + + + + + + prechordal mesoderm + + + + + + + + + multi organ part structure + + + + + + + + + disconnected anatomical group + + + + + + + + + anatomical collection + + + + + + + + + + external soft tissue zone + + + + + + + + + zone of organ + + + + + + + + + jaw mesenchyme + + + + + + + + + jaw epithelium + + + + + + + + + + future mouth + + + + + + + + + + + wall of blood vessel + + + + + + + + + honey + + + + + + + + + regurgitated substance + + + + + + + + + + + + cardiopharyngeal field + + + + + + + + + anatomical surface region + + + + + + + + + secretion of serous membrane + + + + + + + + + orifice of skull + + + + + + + + + vasculature of central nervous system plus retina + + + + + + + + + vasculature of central nervous system + + + + + + + + + + wall of lateral ventricle + + + + + + + + + + + wall of ventricular system of brain + + + + + + + + + + wall of eyeball + + + + + + + + + + wall of heart + + + + + + + + + skin of face + + + + + + + + + digestive tract junction + + + + + + + + + external integument structure + + + + + + + + + head external integument structure + + + + + + + + + body external integument structure + + + + + + + + + vasculature of respiratory integument + + + + + + + + + skeletal element projection + + + + + + + + + intestinal junction + + + + + + + + + excretory system + + + + + + + + + skin of clavicle region + + + + + + + + + phenotype + + + + + + + + + CBL-mediated ubiquitination of CIN85 + + + Ubiquitination of cell cycle proteins targeted by the APC/C:Cdh1complex + + + enabling an MF enables its parts + + + PRKN polyubiquitinates RIPK3 + + + TRAF2,6 ubiquitinates NLRC5 + + + SCF-beta-TRCP ubiquitinates p-7S-p100:RELB in active NIK:p-176,S180-IKKA dimer:p-7S-p100:SCF-beta-TRCP + + + RNF41 ubiquitinates activated ERBB3 + + + enabling an MF enables its parts + + + DDX58 is K63 polyubiquitinated + + + BTRC:CUL1:SKP1 (SCF-beta-TrCP1) ubiquitinylates PER proteins + + + DTX4 ubiquitinates p-S172-TBK1 within NLRP4:DTX4:STING:TBK1:IRF3 + + + DTX4 ubiquitinates p-S172-TBK1 within NLRP4:DTX4:dsDNA:ZBP1:TBK1 + + + Beta-TrCP ubiquitinates NFKB p50:p65:phospho IKBA complex + + + Ubiquitination of DLL/JAG ligands upon binding to NOTCH1 HD+PEST domain mutants + + + Pellino ubiquitinates IRAK1 + + + Autoubiquitination of phospho-COP1(Ser-387 ) + + + Multiubiquitination of APC/C-associated Cdh1 + + + VHL:EloB,C:NEDD8-CUL2:RBX1 complex ubiquitinylates HIF-alpha + + + NHLRC1 mediated ubiquitination of EPM2A (laforin) and PPP1RC3 (PTG) associated with glycogen-GYG2 + + + Ubiquitination of PAK-2p34 + + + ERBB4 ubiquitination by WWP1/ITCH + + + Ubiquitin-dependent degradation of the Smad complex terminates BMP2 signalling + + + ISGylation of E2 conjugating enzymes + + + Myristoylation of tBID by NMT1 + + + RIP2 induces K63-linked ubiquitination of NEMO + + + RNF125 mediated ubiquitination of DDX58, IFIH1 and MAVS + + + CBL neddylates TGFBR2 + + + Ubiquitination of p130 (RBL2) by SCF (Skp2) + + + Ubiquitination of NICD1 by FBWX7 + + + SPATA2:CYLD-bound LUBAC ubiquitinates RIPK1 at K627 within the TNFR1 signaling complex + + + SCF betaTrCP ubiquitinates NFKB p105 within p-S927, S932-NFkB p105:TPL2:ABIN2 + + + CUL5 mediates ubiquitination of ERBB2 + + + effector input is compound function input + + + Ubiquitination of phosphorylated Cdc25A + + + BIRC2/3 (cIAP1/2) is autoubiquitinated + + + CHIP (STUB1) mediates ubiquitination of ERBB2 + + + CBL binds and ubiquitinates phosphorylated Sprouty + + + 'causally upstream of' and 'overlaps' should be disjoint properties (a SWRL rule is required because these are non-simple properties). + + + MIB2 ubiquitinates CYLD at K338, K530 + + + SIAH1, SIAH2 ubiquitinate SNCAIP + + + SCF(beta-TrCP) ubiquitinates p-GLI2 + + + Nuclear VBC complex ubiquitinylates HIF-alpha + + + ARRB mediates NOTCH1 ubiquitination + + + ISGylation of host protein filamin B + + + if effector directly negatively regulates X, its parent MF directly negatively regulates X + + + TRAF6 ubiquitinqtes IRF7 within the activated TLR7/8 or 9 complex + + + beta-TRCP ubiquitinates IkB-alpha in p-S32,33-IkB-alpha:NF-kB complex + + + Activated TRAF6 synthesizes unanchored polyubiquitin chains upon ALPK1:ADP-heptose stimulation + + + Parkin promotes the ubiquitination of mitochondrial substrates + + + RAF1:SGK:TSC22D3:WPP ubiquitinates SCNN channels + + + Ubiquitination of Cyclin A by APC/C:Cdc20 complex + + + Ubiquitination of SKI/SKIL by RNF111/SMURF2 + + + 'causally downstream of' and 'overlaps' should be disjoint properties (a SWRL rule is required because these are non-simple properties). + + + Ubiquitination of stimulated EGFR (CBL) + + + Ubiquitination of Cyclin B by phospho-APC/C:Cdc20 complex + + + if effector directly negatively regulates X, its parent MF directly negatively regulates X + + + The geminin component of geminin:Cdt1 complexes is ubiquitinated, releasing Cdt1 + + + Polyubiquitination of substrate + + + MIB2 ubiquitinates CFLAR + + + SIAH1:UBE2L6:Ubiquitin ubiquitinates SNCA + + + SCF(beta-TrCP) ubiquitinates p-GLI1 + + + cIAP1,2 ubiquitinates NIK in cIAP1,2:TRAF2::TRAF3:NIK + + + Ubiquitination of NOTCH1 by ITCH in the absence of ligand + + + CBL escapes CDC42-mediated inhibition by down-regulating the adaptor molecule Beta-Pix + + + involved in BP + + + Hh processing variants are ubiquitinated + + + Ubiquitination of DLL/JAG ligands upon binding to NOTCH1 PEST domain mutants + + + Activated TRAF6 synthesizes unanchored polyubiquitin chains upon TLR stimulation + + + Auto-ubiquitination of TRAF3 + + + Ubiquitination of CD4 by Vpu:CD4:beta-TrCP:SKP1 complex + + + Ubiquitination of Emi1 by SCF-beta-TrCP + + + ITCH polyubiquitinates MLKL at K50 + + + BRCA1:BARD1 heterodimer autoubiquitinates + + + Ubiquitin-dependent degradation of the SMAD complex terminates TGF-beta signaling + + + RNF41 ubiquitinates ERBB3 + + + Activated TRAF6 synthesizes unanchored polyubiquitin chains upon TLR3 stimulation + + + DDX41 ubiquitination by TRIM21 + + + TRAF6 polyubiquitinates NRIF + + + Cytosolic VBC complex ubiquitinylates hydroxyprolyl-HIF-alpha + + + involved in BP + + + effector input is compound function input + + + K63-linked ubiquitination of RIP1 bound to the activated TLR complex + + + Defective NHLRC1 does not ubiquitinate EPM2A (laforin) and PPP1R3C (PTG) (type 2B disease) + + + SMURF2 monoubiquitinates SMAD3 + + + Activation of ISG15 by UBA7 E1 ligase + + + Auto-ubiquitination of TRAF3 within activated TLR3 complex + + + Cdh1:APC/C ubiquitinates EHMT1 and EHMT2 + + + Ubiquitination of DLL/JAG ligands upon binding to NOTCH2 + + + STING ubiquitination by TRIM32 or TRIM56 + + + Activated TRAF6 synthesizes unanchored polyubiquitin chains + + + Myristoylation of Nef + + + Ubiquitination of NEMO by TRAF6 + + + ISGylation of host proteins + + + ISGylation of viral protein NS1 + + + infer input from direct reg + + + TNFAIP3 (A20) ubiquitinates RIPK1 with K48-linked Ub chains + + + Ubiquitination of DLL/JAG ligands upon binding to NOTCH1 + + + ITCH ubiquitinates DTX + + + E1 mediated ubiquitin activation + + + FN3K phosphorylates ketosamines + + + TRIM33 monoubiquitinates SMAD4 + + + Input of effector is input of its parent MF + + + STUB1 ubiquitinates RIPK1 at K571, K604, K627 + + + RCHY1 monoubiquitinates POLH + + + K63polyUb-TRAF6 ubiquitinates TAK1 + + + SKP1:FBXL5:CUL1:NEDD8 ubiquitinylates IREB2 + + + NEDD4 ubiquitinates ERBB4jmAcyt1s80 dimer + + + inferring direct neg reg edge from input to regulatory subfunction + + + Ubiquitination of phospho-p27/p21 + + + CBL ubiquitinates Sprouty + + + inferring direct reg edge from input to regulatory subfunction + + + Transfer of Ub from E2 to substrate and release of E2 + + + K63polyUb-cIAP1,2 ubiquitinates TRAF3 + + + MIB2 ubiquitinates RIPK1 at K377, K604, K634 + + + RAD18:UBE2B or RBX1:CUL4:DDB1:DTL monoubiquitinates PCNA + + + Ubiquitination of IKBKG by TRAF6 + + + STUB1 ubiquitinates RIPK3 at K55, K363 + + + SYVN1 ubiquitinates Hh C-terminal fragments + + + Ubiquitination of DLL/JAG ligands upon binding to NOTCH1 HD domain mutants + + + Multi-ubiquitination of APOBEC3G + + + Self-ubiquitination of RNF41 + + + TRAF6 is K63 poly-ubiquitinated + + + STUB1 (CHIP) ubiquitinates SMAD3 + + + inferring direct reg edge from input to regulatory subfunction + + + SMURF2 ubiquitinates SMAD2 + + + Input of effector is input of its parent MF + + + Auto ubiquitination of TRAF6 bound to ALPK1:ADP-heptose:TIFA oligomer + + + RNF111 ubiquitinates SMAD7 + + + K63-linked ubiquitination of RIP1 bound to the activated TLR complex + + + Auto ubiquitination of oligo-TRAF6 bound to p-IRAK2 + + + 'causally downstream of' and 'overlaps' should be disjoint properties (a SWRL rule is required because these are non-simple properties). + + + BIRC(cIAP1/2) ubiquitinates RIPK1 + + + Auto-ubiquitination of TRAF6 + + + Ubiquitination of Securin by phospho-APC/C:Cdc20 complex + + + inferring direct positive reg edge from input to regulatory subfunction + + + Ubiquitination of DLL/JAG ligands upon binding to NOTCH3 + + + NHLRC1 mediated ubiquitination of EPM2A and PPP1RC3 associated with glycogen-GYG1 + + + SMURFs/NEDD4L ubiquitinate phosphorylated TGFBR1 and SMAD7 + + + ISGylation of IRF3 + + + FN3KRP phosphorylates PsiAm, RibAm + + + Ubiquitination of Cyclin D1 + + + inferring direct neg reg edge from input to regulatory subfunction + + + SCF-beta-TrCp1/2 ubiquitinates phosphorylated BORA + + + Auto-ubiquitination of TRAF6 + + + ISGylation of protein phosphatase 1 beta (PP2CB) + + + PARK2 K63-Ubiquitinates SNCAIP + + + LUBAC ubiquitinates RIPK1 at K627 + + + inferring direct positive reg edge from input to regulatory subfunction + + + Multiubiquitination of Nek2A + + + SCF(beta-TrCP) ubiquitinates p-GLI3 + + + Ubiquitination of stimulated EGFR (CBL:GRB2) + + + TRAF6 oligomer autoubiquitinates + + + Auto ubiquitination of oligo-TRAF6 bound to p-IRAK2 at endosome membrane + + + 'causally upstream of' and 'overlaps' should be disjoint properties (a SWRL rule is required because these are non-simple properties). + + + + + + + + part of + part of + part_of + + + has part + has part + has_part + + + realized in + + + realizes + + + preceded by + preceded_by + + + precedes + precedes + + + occurs in + occurs in + + + contains process + + + partially_surrounded_by + + + Western Australian Mulga Shrublands Ecoregion + + + Australasia Ecoregion + + + Tirari-Sturt Stony Desert Ecoregion + + + Simpson Desert Region + + + Pilbara Shrublands Ecoregion + + + Carnarvon Xeric Shrublands Ecoregion + + + Central Ranges Xeric Shrub Ecoregion + + + Gibson Desert Ecoregion + + + The Great Sandy-Tanami Desert Ecoregion + + + Great Victoria Desert Ecoregion + + + Nullarbor Plains Xeric Shrubland Ecoregion + + + Afrotropical Ecoregion + + + Succulent Karoo Ecoregion + + + Yemen and Saudi Arabia Ecoregion + + + Yemen, Saudi Arabia, and Oman Ecoregion + + + Somali Montane Xeric Woodland Ecoregion + + + Socotran Archipelago Ecoregion + + + Red Sea Coastal Desert Ecoregion + + + Namibian Savanna Woodland Ecoregion + + + Namib Desert Ecoregion + + + Nama Karoo Ecoregion + + + Masai Xeric Grasslands and Shrublands Ecoregion + + + Madagascar Succulent Woodlands Ecoregion + + + Madagascar Spiny Thickets Ecoregion + + + Kaokoveld Desert Ecoregion + + + Kalahari Xeric Savanna Ecoregion + + + Ile Europa and Bassas da India Ecoregion + + + Hobyo Grassland and Shrubland Ecoregion + + + Oman and United Arab Emirates Ecoregion + + + Ethiopian Xeric Grasslands and Shrublands Ecoregion + + + Eritrean Coastal Desert Ecoregion + + + East Saharan Montane Xeric Woodland Ecoregion + + + Oman, Yemen, and Saudi Arabia Ecoregion + + + Aldabra Island Xeric Scrub Ecoregion + + + Indo-Malay Ecoregion + + + Thar Desert + + + Northwestern Thorn Scrub Forests + + + Arctic front + + + Antarctic front + + + Solar radiation + + + derives from part of + + + has increased levels of + + + results in transformation into + + + results in expansion of + + + results in proliferation of + + + generates + + + example to be eventually removed + + + data about an ontology part + + + failed exploratory term + + + editor preferred term + editor preferred term~editor preferred label + + + example of usage + example of usage + + + in branch + + + has curation status + has curation status + + + definition + definition + + + editor note + editor note + + + term editor + term editor + + + alternative label + alternative term + + + definition source + definition source + + + metadata complete + + + organizational term + + + ready for release + + + metadata incomplete + + + uncurated + + + pending final vetting + + + obsolete_core + + + obsolescence reason specification + + + placeholder removed + + + terms merged + + + term imported + + + term split + + + has obsolescence reason + + + curator note + curator note + + + term tracker item + + + ontology term requester + + + denotator type + + + universal + + + is denotator type + + + imported from + imported from + + + defined class + + + named class expression + + + to be replaced with external ontology term + + + expand expression to + expand expression to + + + expand assertion to + expand assertion to + + + first order logic expression + + + antisymmetric property + + + requires discussion + + + OBO foundry unique label + + + has ID digit count + + + has ID range allocated to + + + has ID policy for + + + has ID prefix + + + elucidation + + + has associated axiom(nl) + + + has associated axiom(fol) + + + is allocated id range + + + has ontology root term + + + may be identical to + + + scheduled for obsoletion on or after + + + has axiom label + + + term replaced by + term replaced by + + + ontology module + + + base ontology module + + + editors ontology module + + + main release ontology module + + + bridge ontology module + + + import ontology module + + + subset ontology module + + + curation subset ontology module + + + analysis subset ontology module + + + single layer subset ontology module + + + exclusion subset ontology module + + + external import ontology module + + + species subset ontology module + + + reasoned ontology module + + + generated ontology module + + + template generated ontology module + + + taxonomic bridge ontology module + + + ontology module subsetted by expressivity + + + obo basic subset ontology module + + + ontology module subsetted by OWL profile + + + EL++ ontology module + + + out of scope + + + logical characteristic of object property + + + defined by construct + + + abbreviation + + + ambiguous synonym + + + dubious synonym + + + layperson synonym + + + plural form + + + UK spelling synonym + + + misspelling + + + misnomer + + + previous name + + + legal name + + + derives_by_manipulation_from + + + isolated from germplasm + + + characteristic of + + + has characteristic + has characteristic + + + participates in + participates_in + + + has participant + has participant + has_participant + + + is concretized as + + + concretizes + + + function of + + + quality of + + + role of + + + has function + + + has quality + + + has role + + + has disposition + + + disposition of + + + derives from + + + derives into + + + location of + + + is allergic trigger for + + + is autoimmune trigger for + + + has allergic trigger + + + has autoimmune trigger + + + located in + located_in + + + temporal interpretation + + + axiom holds for all times + + + relation has no temporal argument + + + 2D boundary of + + + aligned with + + + has 2D boundary + + + electrically_synapsed_to + + + tracheates + + + innervated_by + + + has synaptic terminal of + + + bounding layer of + + + coincident with + + + cell expresses + + + regulates in another organism + + + regulates transport of + + + occurrent part of + + + has regulatory component activity + + + has negative regulatory component activity + + + has positive regulatory component activity + + + has necessary component activity + + + has component activity + + + has component process + + + has ligand + + + transports + + + occurs across + + + directly regulated by + + + directly negatively regulated by + + + directly positively regulated by + + + has effector activity + + + in register with + + + has increased age-specific mortality rate + + + before or simultaneous with + + + simultaneous with + + + before + + + during which ends + + + encompasses + + + ends after + + + immediately preceded by + + + during which starts + + + starts before + + + immediately precedes + + + starts during + + + happens during + + + ends during + + + has soma location + + + fasciculates with + + + axon synapses in + + + synapsed by + + + has plasma membrane part + + + synapsed_via_type_Ib_bouton_to + + + synapsed_via_type_Is_bouton_to + + + synapsed_via_type_II_bouton_to + + + synapsed_by_via_type_II_bouton + + + synapsed_by_via_type_Ib_bouton + + + has postsynaptic terminal in + + + releases neurotransmitter + + + synapsed_by_via_type_Is_bouton + + + has presynaptic terminal in + + + synapsed_via_type_III_bouton_to + + + synapsed_by_via_type_III_bouton + + + synapsed to + + + dendrite synapsed in + + + has synaptic terminal in + + + overlaps + + + has fasciculating neuron projection + + + innervates + + + continuous with + + + partially overlaps + + + derived by descent from + + + has derived by descendant + + + shares ancestor with + + + serially homologous to + + + only in taxon + only_in_taxon + + + never in taxon + + + in taxon + + + spatially disjoint from + + + connected to + + + mutually spatially disjoint with + + + taxonomic class assertion + + + ambiguous for taxon + + + dubious for taxon + + + present in taxon + + + connects + connects + + + attached to part of + + + supplies + + + drains + + + has component + + + has phenotype + + + phenotype of + + + develops from + develops_from + + + develops into + + + gene product of + + + has gene product + + + expressed in + + + directly develops from + + + parasitoid of + + + has parasitoid + + + directly develops into + + + regulates + regulates (processual) + + + negatively regulates + + + positively regulates + + + has prototype + + + capable of + + + capable of part of + + + surrounded by + surrounded by + + + adjacent to + adjacent_to + + + surrounds + + + temporally related to + + + starts + + + starts with + + + develops from part of + + + develops in + + + obligate parasite of + + + facultative parasite of + + + ends + + + ends with + + + has start location + + + has end location + + + has input + + + has output + + + stem parasite of + + + root parasite of + + + hemiparasite of + + + has component participant + + + has exposure receptor + + + has exposure stressor + + + has exposure route + + + has exposure transport path + + + related via exposure to + + + over-expressed in + + + under-expressed in + + + has active ingredient + + + active ingredient in + + + connecting branch of + + + has connecting branch + + + has developmental contribution from + + + developmentally contributes to + + + developmentally induced by + + + developmentally induces + + + developmentally preceded by + developmentally_preceded_by + + + defined by inverse + + + has biological role + + + has application role + + + has chemical role + + + acts upstream of + + + acts upstream of or within + + + developmentally replaces + + + developmentally succeeded by + + + part of developmental precursor of + + + ubiquitously expressed in + + + expresses + + + ubiquitously expresses + + + results in developmental progression of + + + results in development of + + + results in formation of + results in formation of anatomical entity + + + results in morphogenesis of + + + results in maturation of + + + results in disappearance of + + + results in developmental regression of + + + is treated by substance + + + has habitat + has habitat + + + causally upstream of, positive effect + + + causally upstream of, negative effect + + + has exposure stimulus + + + evolutionary variant of + + + transports or maintains localization of + + + characteristic of part of + + + results in acquisition of features of + + + evolutionarily related to + + + ecologically related to + + + confers advantage in + + + mereotopologically related to + + + developmentally related to + + + colocalizes with + + + contributes to + + + enables + + + functionally related to + + + part of structure that is capable of + + + genomically related to + + + involved in + + + regulates levels of + + + enabled by + enabled by + + + regulated by + + + negatively regulated by + + + positively regulated by + + + related via localization to + + + has target start location + + + has target end location + + + imports + + + results in transport along + + + results in transport across + + + results in growth of + + + results in transport to from or in + + + exports + + + results in commitment to + + + results in determination of + + + member of + + + has member + + + input of + + + output of + + + formed as result of + + + results in structural organization of + + + results in specification of + + + results in developmental induction of + + + has dendrite location + + + attached to + + + has muscle origin + + + has muscle insertion + + + derived from ancestral fusion of + + + in branching relationship with + + + tributary of + + + distributary of + + + anabranch of + + + spatially coextensive with + + + branching part of + + + main stem of + + + proper distributary of + + + proper tributary of + + + has developmental potential involving + + + has potential to developmentally contribute to + + + has potential to developmentally induce + + + has potential to develop into + + + has potential to directly develop into + + + has direct input + + + causally downstream of + + + immediately causally downstream of + + + indirectly positively regulates + + + indirectly negatively regulates + + + causally related to + + + causally upstream of + + + immediately causally upstream of + + + provides input for + + + transitively provides input for + + + logical macro assertion + + + causally upstream of or within + + + annotation property cardinality + + + logical macro assertion on a class + + + logical macro assertion on a property + + + logical macro assertion on an object property + + + logical macro assertion on an annotation property + + + differs in + + + differs in attribute of + + + differs in attribute + + + causally downstream of or within + + + involved in regulation of + + + involved in positive regulation of + + + involved in negative regulation of + + + involved in or involved in regulation of + + + is active in + + + contributes to morphology of + + + interacts with + + + genetically interacts with + + + molecularly interacts with + + + biotically interacts with + + + trophically interacts with + + + preys on + + + symbiotically interacts with + + + commensually interacts with + + + mutualistically interacts with + + + interacts with via parasite-host interaction + + + parasite of + + + parasitized by + + + participates in a abiotic-biotic interaction with + + + phosphorylates + + + directly regulates activity of + + + directly negatively regulates activity of + + + directly positively regulates activity of + + + transmitted by + + + has symptom + + + host of + + + has host + + + pollinates + + + pollinated by + + + acquires nutrients from + + + preyed upon by + + + is vector for + + + has vector + + + partner in + + + subject participant in + + + target participant in + + + helper property (not for use in curation) + + + is symbiosis + + + is commensalism + + + is mutualism + + + is parasitism + + + provides nutrients for + + + eats + + + is eaten by + + + is evidence for + + + composed primarily of + + + dispositional interpretation + + + has no connections with + + + child nucleus of + + + child nucleus of in hermaphrodite + + + child nucleus of in male + + + has part that occurs in + + + ubiquitinates + + + is kinase activity + + + is ubiquitination + + + inherited annotation property + + + curator guidance link + + + receives input from + + + sends output to + + + relation between physical entity and a process or stage + + + existence starts during + + + existence starts with + + + existence overlaps + + + existence starts and ends during + + + existence ends during + + + existence ends with + + + transformation of + + + immediate transformation of + + + existence starts during or after + + + existence ends during or before + + + causal agent in process + + + causal relation between processes + + + depends on + + + towards + + + always present in taxon + + + has intermediate + + + causal relation between entities + + + determined by + + + determines + + + determined by part of + + + transcribed from + + + transcribed to + + + ribosomal translation of + + + ribosomally translates to + + + sequentially related to + + + sequentially adjacent to + + + has start sequence + + + is start sequence of + + + has end sequence + + + is end sequence of + + + is consecutive sequence of + + + is sequentially aligned with + + + bounds sequence of + + + is bound by sequence of + + + has subsequence + + + is subsequence of + + + overlaps sequence of + + + does not overlap sequence of + + + is upstream of sequence of + + + is downstream of sequence of + + + is immediately downstream of sequence of + + + is immediately upstream of sequence of + + + temporal logical macro assertion on a class + + + measurement property has unit + + + has start time value + + + has end time value + + + start, days post fertilization + + + end, days post fertilization + + + start, years post birth + + + end, years post birth + + + start, months post birth + + + end, months post birth + + + month of gestation + + + has developmental stage marker + + + start, days post coitum + + + end, days post coitum + + + start, weeks post birth + + + end, weeks post birth + + + has skeleton + + + results in ending of + + + hyperparasite of + + + hyperparasitized by + + + allelopath of + + + pathogen of + + + has pathogen + + + has evidence + + + causally influenced by + + + is asymmetric relational form of process class + + + is symmetric relational form of process class + + + is relational form of process class + + + interaction relation helper property + + + molecular interaction relation helper property + + + results in movement of + + + causally influences + + + biomechanically related to + + + has muscle antagonist + + + has branching part + + + conduit for + + + lumen of + + + luminal space of + + + has modifier + + + participates in a biotic-biotic interaction with + + + is direct form of + + + skeleton of + + + directly regulates + + + is indirect form of + + + logical macro assertion on an axiom + + + is a defining property chain axiom + + + is a defining property chain axiom where second argument is reflexive + + + existence starts at end of + + + has part structure that is capable of + + + results in closure of + + + results in breakdown of + + + results in synthesis of + + + results in assembly of + + + results in catabolism of + + + results in disassembly of + + + results in remodeling of + + + results in organization of + + + existence ends at start of + + + is relational form of a class + + + causal relation between material entity and a process + + + capable of regulating + + + capable of negatively regulating + + + capable of positively regulating + + + capable of inhibiting or preventing pathological process + + + capable of upregulating or causing pathological process + + + logical macro assertion involving identity + + + in approximate one to one relationship with + + + is approximately equivalent to + + + is opposite of + + + is indistinguishable from + + + is substance that treats + + + is marker for + + + process has causal agent + + + correlated with + + + evidential logical macro assertion on an axiom + + + axiom has evidence + + + axiom contradicted by evidence + + + is evidence with support from + + + has model + + + related via evidence or inference to + + + is representative IRI for equivalence set + + + visits + + + visited by + + + visits flowers of + + + has flowers visited by + + + lays eggs in + + + has eggs laid in by + + + kills + + + is killed by + + + directly positively regulates + + + directly negatively regulates + + + ectoparasite of + + + has ectoparasite + + + endoparasite of + + + has endoparasite + + + mesoparasite of + + + has mesoparasite + + + intercellular endoparasite of + + + has intercellular endoparasite + + + intracellular endoparasite of + + + has intracellular endoparasite + + + co-roosts with + + + reservoir host of + + + has reservoir host + + + produces + + + produced by + + + represses expression of + + + increases expression of + + + has role in modeling + + + causes or contributes to condition + + + causes condition + + + contributes to condition + + + contributes to severity of condition + + + contributes to frequency of condition + + + ameliorates condition + + + correlated with condition + + + exacerbates condition + + + condition ameliorated by + + + condition exacerbated by + + + condition has genetic basis in + + + has material basis in gain of function germline mutation in + + + has material basis in loss of function germline mutation in + + + has material basis in germline mutation in + + + has material basis in somatic mutation in + + + has major susceptibility factor + + + has partial material basis in germline mutation in + + + has primary input or output + + + has primary output + + + has primary input + + + is genetic basis for condition + + + is causal gain of function germline mutation of in + + + is causal loss of function germline mutation of in + + + is causal germline mutation in + + + is causal somatic mutation in + + + is causal susceptibility factor for + + + is causal germline mutation partially giving rise to + + + realizable has basis in + + + is basis for realizable + + + disease has basis in + + + disease has basis in dysfunction of + + + disease has basis in disruption of + + + disease has basis in feature + + + causal relationship with disease as subject + + + disease causes disruption of + + + disease causes dysfunction of + + + disease has location + + + disease has inflammation site + + + realized in response to stimulus + + + disease has feature + + + disease arises from alteration in structure + + + enables subfunction + + + acts upstream of or within, positive effect + + + acts upstream of or within, negative effect + + + acts upstream of, positive effect + + + acts upstream of, negative effect + + + nominally disjoint with + + + causally upstream of or within, negative effect + + + causally upstream of or within, positive effect + + + is directional form of + + + is positive form of + + + is negative form of + + + has driver + + + has disease driver + + + epiphyte of + + + has epiphyte + + + kleptoparasite of + + + kleptoparasitized by + + + creates habitat for + + + ecologically co-occurs with + + + lays eggs on + + + has eggs laid on by + + + has roost + + + has substance added + + + has substance removed + + + immersed in + + + has consumer + + + has primary substance added + + + realized in response to + + + generically depends on + + + is carrier of + + + regulates activity of + + + regulates quantity of + + + indirectly regulates activity of + + + decreases by repression quantity of + + + increases by expression quantity of + + + directly positively regulates quantity of + + + directly negatively regulates quantity of + + + indirectly positively regulates activity of + + + destabilizes quantity of + + + stabilizes quantity of + + + indirectly negatively regulates activity of + + + directly regulates quantity of + + + indirectly regulates quantity of + + + indirectly negatively regulates quantity of + + + indirectly positively regulates quantity of + + + has small molecule regulator + + + has small molecule activator + + + has small molecule inhibitor + + + acts on population of + + + is small molecule regulator of + + + is small molecule activator of + + + is small molecule inhibitor of + + + results in adhesion of + + + results in fusion of + + + constitutively upstream of + + + removes input for + + + indirectly causally upstream of + + + indirectly regulates + + + positively regulates in another organism + + + negatively regulates in another organism + + + has synaptic IO in region + + + receives synaptic input in region + + + sends synaptic output to region + + + has synaptic IO throughout + + + receives synaptic input throughout + + + sends synaptic output throughout + + + has sensory dendrite in + + + receives synaptic input from neuron + + + sends synaptic output to cell + + + disease has infectious agent + + + has exemplar data + + + exemplar data of + + + subcluster of + + + has characterizing marker set + + + different in magnitude relative to + + + increased in magnitude relative to + + + decreased in magnitude relative to + + + similar in magnitude relative to + + + has relative magnitude + + + has cross section + + + reciprocal of + + + has high plasma membrane amount + + + has low plasma membrane amount + + + has phenotype or disease + + + has disease + + + has exposure medium + + + device utilizes material + + + positively correlated with + + + negatively correlated with + + + contains measured amount + + + is myristoyltransferase activity + + + myristoylates + + + myristoylated by + + + is agonist of + + + is inverse agonist of + + + is antagonist of + + + chemical relationship + + + is direct conjugate base of + + + is direct conjugate acid of + + + is deprotonated form of + + + is protonated form of + + + is matched small molecular pair with + + + is tautomer of + + + is substitutent group from + + + has functional parent + + + is enantiomer of + + + has parent hydride + + + regulates characteristic + + + positively regulates characteristic + + + negatively regulates characteristic + + + confers susceptibility to condition + + + vessel supplies blood to + + + vessel drains blood from + + + directly supplies and drains + + + disease relationship + + + results in changes to anatomical or cellular structure + + + is homeomorphic for + + + in similarity relationship with + + + in homology relationship with + + + in homoplasy relationship with + + + in homocracy relationship with + + + in convergence relationship with + + + in parallelism relationship with + + + in structural homology relationship with + + + in historical homology relationship with + + + in biological homology relationship with + + + in reversal relationship with + + + in syntenic homology relationship with + + + in paralogy relationship with + + + in syntenic paralogy relationship with + + + in syntenic orthology relationship with + + + in partial homology relationship with + + + in protein structural homology relationship with + + + in non functional homology relationship with + + + in orthology relationship with + + + in xenology relationship with + + + in 1 to 1 homology relationship with + + + in 1 to 1 orthology relationship with + + + in ohnology relationship with + + + in in-paralogy relationship with + + + in out-paralogy relationship with + + + in pro-orthology relationship with + + + in semi-orthology relationship with + + + in serial homology relationship with + + + in heterochronous homology relationship with + + + in paedomorphorsis relationship with + + + in peramorphosis relationship with + + + in progenesis relationship with + + + in neoteny relationship with + + + in mimicry relationship with + + + in 1 to many orthology relationship with + + + in many to many homology relationship with + + + in 1 to many homology relationship with + + + in apomorphy relationship with + + + in plesiomorphy relationship with + + + in deep homology relationship with + + + in hemiplasy relationship with + + + in gametology relationship with + + + in chromosomal homology relationship with + + + in many to many orthology relationship with + + + in within-species paralogy relationship with + + + in between-species paralogy relationship with + + + in postdisplacement relationship with + + + in hypermorphosis relationship with + + + in synology relationship with + + + in isoorthology relationship with + + + in tandem paralogy relationship with + + + in latent homology relationship with + + + in syngeny relationship with + + + in apparent orthology relationship with + + + in pseudoparalogy relationship with + + + in equivalogy relationship with + + + in interology relationship with + + + in functional equivalence relationship with + + + in iterative homology relationship with + + + in paraxenology relationship with + + + in plerology relationship with + + + in homotopy relationship with + + + in homeosis relationship with + + + in homoeology relationship with + + + in paramorphism relationship with + + + in regulogy relationship with + + + valid_for_go_annotation_extension + + + valid_for_go_gp2term + + + valid_for_go_ontology + + + valid_for_gocam + + + disconnected_from + + + German synonym (exact) + + + Japanese synonym (exact) + + + Spanish synonym (exact) + + + eco subset + + + subset_property + + + synonym_type_property + + + consider + + + has_alternative_id + + + has broad synonym + has_broad_synonym + + + database_cross_reference + + + has exact synonym + has_exact_synonym + + + has narrow synonym + has_narrow_synonym + + + has_obo_format_version + + + has_obo_namespace + + + has related synonym + has_related_synonym + + + has_scope + + + has_synonym_type + + + in_subset + + + shorthand + + + treat-xrefs-as-genus-differentia + + + treat-xrefs-as-is_a + + + Aleix Puig-Barbé + + + Austin Meier + + + Shawn Zheng Kai Tan + + + Lynn Schriml + + + Anne Thessen + + + Jie Zheng + + + Pier Luigi Buttigieg + + + Christian J Stoeckert + + + Christopher J. Mungall + + + David Osumi-Sutherland + + + Lauren E. Chan + + + Marie-Angélique Laporte + + + James P. Balhoff + + + Lindsay G Cowell + + + Pascale Gaudet + + + S. Clint Dowland + + + Anna Maria Masci + + + Jorrit Poelen + + + Charles Tapley Hoyt + + + Earth + + + Suni + + + Sol + + + World Ocean + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + diff --git a/src/ontology/nmdco-classes-struct-diff.txt b/src/ontology/nmdco-classes-struct-diff.txt new file mode 100644 index 0000000..eee0a6a --- /dev/null +++ b/src/ontology/nmdco-classes-struct-diff.txt @@ -0,0 +1,551 @@ +robot diff --left nmdco-classes.owl --right nmdco-classes-no-rg.owl | grep -v AnnotationAssertion > nmdco-classes-struct-diff.txt + +452 axioms in left ontology (Elk 0.4.3) but not in right ontology (Elk 0.5.0): + +- Annotation(owl:versionInfo "2024-02-16") +- OntologyID(OntologyIRI() VersionIRI()) + +295 SubClassOf axioms lost +- SubClassOf( owl:Thing) +- SubClassOf( ) # role sco quality +- SubClassOf( owl:Thing) +- SubClassOf( owl:Thing) +- SubClassOf( owl:Thing) +- SubClassOf( owl:Thing) +- SubClassOf( ) # role sco realizable entity +- SubClassOf( owl:Thing) + + +- SubClassOf( ) # farm sco ABP +- SubClassOf( ) # glacier sco mass of solid material +- SubClassOf( ) # ice shelf sco anatomical structure +- SubClassOf( ) # metalimnion sco fluid astronomical body part +- SubClassOf( ) # metalimnion sco compound astronomical body part +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) # anchored ice calf sco anatomical structure +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) # hail sco object aggregate +- SubClassOf( ) # depth of water ice sco depth +- SubClassOf( ) # stream water sco fluid astronomical body part +- SubClassOf( ) # lake water sco fluid astronomical body part + +- SubClassOf( owl:Thing) +- SubClassOf( owl:Thing) +- SubClassOf( ) # population of organisms sco organism + +Lost 183 sco +- SubClassOf( ) # cultured somatic plant embryo +- SubClassOf( ) # cultured somatic plant embryo sco anatomical entity +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) + +- SubClassOf( owl:Thing) + +LOST 41 SCO +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) +- SubClassOf( ) + +- SubClassOf( owl:Thing) + +382 axioms in right ontology (Elk 0.5.0) but not in left ontology (Elk 0.4.3): + ++ Annotation(owl:versionInfo "2024-03-01") ++ OntologyID(OntologyIRI() VersionIRI()) + +2 added classes ++ Declaration(Class()) ++ Declaration(Class()) + +166 added DisjointClasses axioms ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) ++ DisjointClasses( ) + ++ DisjointUnion( ) + +56 added SubClassOf axioms: ++ SubClassOf( ) ++ SubClassOf( ) ++ SubClassOf( ) ++ SubClassOf( ) ++ SubClassOf( ) ++ SubClassOf( ) ++ SubClassOf( ObjectComplementOf()) ++ SubClassOf( ) ++ SubClassOf( ) ++ SubClassOf( ) ++ SubClassOf( ) ++ SubClassOf( ) ++ SubClassOf( ) ++ SubClassOf( ) ++ SubClassOf( ) ++ SubClassOf( ObjectComplementOf()) ++ SubClassOf( ) ++ SubClassOf( ) ++ SubClassOf( ) ++ SubClassOf( ) ++ SubClassOf( ) ++ SubClassOf( ) ++ SubClassOf( ) ++ SubClassOf( ) ++ SubClassOf( ) ++ SubClassOf( ) ++ SubClassOf( ) ++ SubClassOf( ) ++ SubClassOf( ) ++ SubClassOf( ) ++ SubClassOf( ) ++ SubClassOf( ) ++ SubClassOf( ) ++ SubClassOf( ) ++ SubClassOf( ) ++ SubClassOf( ) ++ SubClassOf( ) ++ SubClassOf( ) ++ SubClassOf( ) ++ SubClassOf( ) ++ SubClassOf( ) ++ SubClassOf( ) ++ SubClassOf( ) ++ SubClassOf( ) ++ SubClassOf( ) ++ SubClassOf( ) ++ SubClassOf( ) ++ SubClassOf( ) ++ SubClassOf( ) ++ SubClassOf( ) ++ SubClassOf( ) ++ SubClassOf( ) ++ SubClassOf( ) ++ SubClassOf( ) ++ SubClassOf( ) ++ SubClassOf( ) diff --git a/src/ontology/nmdco-classes.owl b/src/ontology/nmdco-classes.owl index 76c0556..6d6270a 100644 --- a/src/ontology/nmdco-classes.owl +++ b/src/ontology/nmdco-classes.owl @@ -7,8 +7,8 @@ xmlns:xsd="http://www.w3.org/2001/XMLSchema#" xmlns:rdfs="http://www.w3.org/2000/01/rdf-schema#"> - - 2024-03-01 + + 2024-02-16 @@ -27,6 +27,7 @@ + entity @@ -36,7 +37,6 @@ - continuant @@ -55,8 +55,6 @@ - - independent continuant @@ -66,8 +64,6 @@ - - spatial region @@ -77,9 +73,6 @@ - - - temporal region @@ -107,7 +100,6 @@ - disposition @@ -117,7 +109,6 @@ - realizable realizable entity @@ -137,7 +128,6 @@ - characteristic specifically dependent continuant @@ -149,7 +139,7 @@ - + role @@ -232,7 +222,6 @@ - material entity material entity @@ -261,7 +250,6 @@ - one-dimensional continuant fiat boundary @@ -278,25 +266,33 @@ - + + + - + + + - + + + - + + + @@ -1736,7 +1732,6 @@ - biological role @@ -3672,7 +3667,6 @@ - application @@ -7725,7 +7719,7 @@ - + role @@ -7774,7 +7768,6 @@ - chemical role @@ -9139,6 +9132,7 @@ + measurement datum @@ -9414,7 +9408,6 @@ - dead cave @@ -9587,11 +9580,6 @@ - - - - - hot spring @@ -9839,6 +9827,7 @@ + farm @@ -9992,7 +9981,6 @@ - caldera @@ -10175,7 +10163,6 @@ - plantation @@ -10311,6 +10298,7 @@ + glacier @@ -10900,7 +10888,6 @@ - meromictic lake @@ -10964,7 +10951,6 @@ - marine neritic zone @@ -11993,7 +11979,6 @@ - crevasse @@ -12168,7 +12153,6 @@ - particle of sand @@ -12527,6 +12511,7 @@ + ice shelf @@ -12939,8 +12924,6 @@ - - biome @@ -14074,11 +14057,6 @@ - - - - - talik @@ -14305,7 +14283,6 @@ - rock @@ -14925,7 +14902,8 @@ - + + metalimnion @@ -15083,6 +15061,7 @@ + sea water @@ -15155,7 +15134,7 @@ - + ditch water @@ -15619,7 +15598,7 @@ - + pond water @@ -16145,7 +16124,6 @@ - clay @@ -17655,7 +17633,6 @@ - silt @@ -17784,7 +17761,6 @@ - neritic pelagic zone biome @@ -18110,7 +18086,7 @@ - + oceanic front @@ -18129,6 +18105,7 @@ + marine oligotrophic desert @@ -18447,6 +18424,7 @@ + marine cold-water sphere @@ -19869,8 +19847,9 @@ - + + nutricline within a water body @@ -19961,7 +19940,6 @@ - mudstone @@ -20074,7 +20052,6 @@ - amictic lake @@ -20093,8 +20070,6 @@ - - dimictic lake @@ -20104,7 +20079,6 @@ - polymictic lake @@ -20236,7 +20210,7 @@ - + estuarine water @@ -20420,6 +20394,7 @@ + sea water environment @@ -20437,6 +20412,7 @@ + atmospheric boundary layer @@ -20546,6 +20522,7 @@ + understory @@ -20555,6 +20532,7 @@ + shrub layer @@ -20564,6 +20542,7 @@ + herb and fern layer @@ -20574,6 +20553,8 @@ + + litter layer @@ -23204,6 +23185,7 @@ + plant litter @@ -23548,7 +23530,6 @@ - waste role @@ -24218,7 +24199,6 @@ - habitat @@ -24368,6 +24348,7 @@ + cloud @@ -24404,7 +24385,6 @@ - formal settlement @@ -24423,7 +24403,6 @@ - legal settlement @@ -25580,6 +25559,7 @@ + area of woody wetland @@ -25817,6 +25797,7 @@ + glacial ice ablation process @@ -26172,6 +26153,7 @@ + terrestrial planet @@ -26643,6 +26625,7 @@ + hydrometeor @@ -26752,11 +26735,6 @@ - - - - - natural lake @@ -27184,6 +27162,7 @@ + meteoroid @@ -28021,7 +28000,6 @@ - cirrus cloud @@ -28446,7 +28424,6 @@ - ranch @@ -28916,7 +28893,7 @@ - + saline shrimp pond water @@ -29256,6 +29233,7 @@ + convective storm @@ -29340,7 +29318,6 @@ - environmental role @@ -29396,7 +29373,6 @@ - liquid surface layer @@ -29632,6 +29608,7 @@ + anchor ice @@ -30158,7 +30135,7 @@ - + accumulation of matter on aerosolised particles @@ -30279,7 +30256,6 @@ - cirrocumulus cloud @@ -30290,7 +30266,6 @@ - cirrostratus cloud @@ -30300,7 +30275,6 @@ - altocumulus cloud @@ -30329,7 +30303,6 @@ - stratocumulus cloud @@ -30340,7 +30313,6 @@ - stratus cloud @@ -30351,7 +30323,6 @@ - cumulus cloud @@ -30480,6 +30451,7 @@ + water-based cloud @@ -30524,6 +30496,7 @@ + terrestrial mining @@ -30982,7 +30955,7 @@ - + surface of an astronomical body @@ -31063,6 +31036,7 @@ + satellite imaging @@ -31073,7 +31047,6 @@ - satellite imaging of a planet @@ -31092,6 +31065,7 @@ + dioxygen dissolved in marine water @@ -31214,6 +31188,7 @@ + anchored ice calf @@ -31346,6 +31321,7 @@ + fast ice @@ -31788,6 +31764,7 @@ + sea surface layer @@ -31926,6 +31903,7 @@ + snow and ice accumulation process @@ -31936,6 +31914,7 @@ + mass of ice and snow @@ -32027,6 +32006,7 @@ + agricultural pollution @@ -32097,24 +32077,6 @@ - - - - - glaciation - - - - - - - - - interglacial - - - - @@ -32392,6 +32354,7 @@ + fluid surface layer @@ -32419,7 +32382,8 @@ - + + marine cline @@ -32428,6 +32392,7 @@ + fluid interface layer @@ -32455,7 +32420,6 @@ - gaseous front @@ -32485,8 +32449,6 @@ - - gaseous surface layer @@ -34701,6 +34663,7 @@ + blood material @@ -34784,6 +34747,7 @@ + cerebrospinal fluid material @@ -34794,6 +34758,7 @@ + chyle material @@ -34822,6 +34787,7 @@ + pleural effusion material @@ -34877,6 +34843,7 @@ + synovial fluid material @@ -34896,6 +34863,7 @@ + lymph material @@ -35467,7 +35435,6 @@ - research nuclear reactor @@ -35918,6 +35885,7 @@ + environmental monitoring @@ -37207,6 +37175,7 @@ + hail @@ -37260,6 +37229,7 @@ + depth of water ice @@ -41149,7 +41119,7 @@ - + stream water @@ -41251,7 +41221,7 @@ - + lake water @@ -41662,7 +41632,6 @@ - litter role @@ -48451,7 +48420,6 @@ - gene product or complex activity molecular_function @@ -48948,6 +48916,7 @@ + curation status specification @@ -50857,6 +50826,7 @@ + root node @@ -51368,7 +51338,6 @@ - branched @@ -51560,7 +51529,6 @@ - closed @@ -51806,7 +51774,6 @@ - permeable @@ -51825,7 +51792,6 @@ - porous @@ -51990,7 +51956,6 @@ - elastic @@ -52035,7 +52000,6 @@ - linear @@ -52091,7 +52055,6 @@ - process quality @@ -52411,7 +52374,6 @@ - aerobic @@ -52607,7 +52569,6 @@ - distributed @@ -53223,7 +53184,6 @@ - wet @@ -53364,7 +53324,6 @@ - hydrophobicity @@ -53758,7 +53717,6 @@ - laminar @@ -53778,7 +53736,6 @@ - edible @@ -54655,6 +54612,7 @@ + population of organisms @@ -54812,8 +54770,10 @@ + + cultured somatic plant embryo @@ -54822,7 +54782,9 @@ + + apical hook @@ -54958,7 +54920,9 @@ + + tetrad of microspores @@ -54977,11 +54941,6 @@ - - - - - vascular system @@ -55210,10 +55169,6 @@ - - - - root initial cell @@ -55366,7 +55321,9 @@ + + plant sperm cell @@ -55384,8 +55341,9 @@ + - + socket cell @@ -55547,7 +55505,9 @@ + + root hair cell @@ -55565,7 +55525,9 @@ + + trichoblast @@ -55574,7 +55536,9 @@ + + non-hair root epidermal cell @@ -55601,7 +55565,9 @@ + + trichome @@ -55620,7 +55586,6 @@ - subsidiary cell @@ -55639,7 +55604,6 @@ - tracheary element @@ -55648,8 +55612,9 @@ + - + guard cell @@ -55659,9 +55624,6 @@ - - - cambial initial cell @@ -55688,8 +55650,9 @@ + - + shoot epidermal pavement cell @@ -55699,8 +55662,6 @@ - - plant epidermal initial cell @@ -55709,7 +55670,9 @@ + + guard mother cell @@ -56393,7 +56356,9 @@ + + embryo basal cell @@ -56519,7 +56484,9 @@ + + root nodule @@ -56744,7 +56711,9 @@ + + bark @@ -56816,7 +56785,9 @@ + + axial secondary xylem parenchyma cell @@ -56825,7 +56796,9 @@ + + ray secondary xylem parenchyma cell @@ -56897,7 +56870,9 @@ + + fruit placenta @@ -56906,7 +56881,9 @@ + + infructescence fruit pedicel @@ -56960,8 +56937,10 @@ + + shoot axis tuber @@ -57468,7 +57447,9 @@ + + root primordium @@ -57504,7 +57485,9 @@ + + primary thickening meristem @@ -57632,7 +57615,6 @@ - xylem @@ -57660,7 +57642,6 @@ - phloem @@ -57804,7 +57785,9 @@ + + epidermis plant epidermis @@ -57851,7 +57834,9 @@ + + primary xylem @@ -57860,7 +57845,9 @@ + + caryopsis hull @@ -57869,7 +57856,9 @@ + + phyllome @@ -57950,7 +57939,9 @@ + + primary parietal cell @@ -58412,7 +58403,9 @@ + + primary phloem @@ -58493,7 +58486,9 @@ + + primary sporogenous cell @@ -58574,7 +58569,9 @@ + + sporocyte @@ -58745,7 +58742,9 @@ + + tassel spikelet @@ -58918,7 +58917,9 @@ + + seed raphe @@ -58927,7 +58928,9 @@ + + seed funicle @@ -58936,7 +58939,9 @@ + + seed chalaza @@ -58945,7 +58950,9 @@ + + seed micropyle @@ -58954,7 +58961,9 @@ + + seed obturator @@ -59000,6 +59009,7 @@ + infructescence @@ -59010,7 +59020,9 @@ + + axillary shoot system @@ -61122,7 +61134,9 @@ + + trichome cell @@ -61232,7 +61246,9 @@ + + fruit @@ -61242,11 +61258,6 @@ - - - - - plant cell @@ -61255,7 +61266,9 @@ + + root @@ -61265,7 +61278,6 @@ - shoot system @@ -61275,10 +61287,6 @@ - - - - portion of plant tissue @@ -61305,7 +61313,9 @@ + + seed @@ -61600,7 +61610,9 @@ + + flower @@ -61618,6 +61630,7 @@ + inflorescence @@ -61692,7 +61705,6 @@ - perianth @@ -61719,7 +61731,9 @@ + + androecium @@ -61728,7 +61742,9 @@ + + gynoecium @@ -61764,7 +61780,9 @@ + + anther @@ -61936,7 +61954,9 @@ + + aril @@ -61954,7 +61974,9 @@ + + long lateral tassel branch @@ -61963,7 +61985,9 @@ + + short tassel branch @@ -62018,8 +62042,10 @@ + + inflorescence apical meristem @@ -62120,7 +62146,9 @@ + + plant ovule @@ -62247,7 +62275,9 @@ + + obturator @@ -62510,7 +62540,6 @@ - coma @@ -62663,7 +62692,9 @@ + + suspensor @@ -62771,7 +62802,9 @@ + + columella root cap cell @@ -63198,7 +63231,6 @@ - leptoid @@ -63432,7 +63464,9 @@ + + portion of ground tissue @@ -63569,7 +63603,9 @@ + + embryo sac @@ -63959,7 +63995,9 @@ + + archegonium egg cell @@ -63996,7 +64034,9 @@ + + archegonium @@ -64014,7 +64054,9 @@ + + phyllome primordium @@ -64087,7 +64129,6 @@ - free tepal @@ -64625,7 +64666,9 @@ + + pollen tube cell @@ -64920,7 +64963,9 @@ + + tetrad of megaspores @@ -65029,6 +65074,7 @@ + second order inflorescence @@ -65039,6 +65085,7 @@ + second order infructescence @@ -65049,7 +65096,9 @@ + + infructescence axis @@ -65229,7 +65278,9 @@ + + plant ovary septum @@ -65283,7 +65334,9 @@ + + fruit septum @@ -65301,7 +65354,9 @@ + + fruit locule @@ -65391,7 +65446,9 @@ + + pollen @@ -65400,6 +65457,7 @@ + archegonium megagametophyte @@ -65419,8 +65477,10 @@ + + embryo apical cell @@ -65448,7 +65508,9 @@ + + seedling coleoptile @@ -65467,7 +65529,9 @@ + + seedling coleorhiza @@ -65486,7 +65550,9 @@ + + seedling hypocotyl @@ -65505,7 +65571,9 @@ + + seedling epicotyl @@ -65524,7 +65592,9 @@ + + seedling mesocotyl @@ -65553,7 +65623,6 @@ - fruit operculum @@ -65572,7 +65641,9 @@ + + seedling hypocotyl-root junction @@ -66541,7 +66612,9 @@ + + primary vascular tissue @@ -66550,7 +66623,9 @@ + + secondary vascular tissue @@ -67464,7 +67539,9 @@ + + archegonium central cell @@ -67600,7 +67677,9 @@ + + ventral canal cell @@ -67690,7 +67769,9 @@ + + adventitious shoot axis @@ -68332,7 +68413,9 @@ + + fruit pedicel abscission zone @@ -68350,7 +68433,9 @@ + + vegetative shoot system @@ -68368,6 +68453,7 @@ + shoot axis tegument layer @@ -68504,7 +68590,9 @@ + + endodermis cell @@ -68675,8 +68763,10 @@ + + non-vascular leaf meristematic apical cell @@ -68721,7 +68811,9 @@ + + gametophore @@ -68797,7 +68889,9 @@ + + gametophore bud @@ -68842,6 +68936,7 @@ + gametophyte perianth @@ -68870,6 +68965,7 @@ + archegoniophore @@ -68898,7 +68994,9 @@ + + spore capsule calyptra @@ -69007,7 +69105,6 @@ - sporangium wall endothecium @@ -69151,7 +69248,9 @@ + + archegonium neck canal cell @@ -69205,7 +69304,9 @@ + + epidermal rhizoid @@ -69250,6 +69351,7 @@ + archegonium head @@ -69278,7 +69380,9 @@ + + protonemal rhizoid @@ -69800,6 +69904,7 @@ + sequentially ordered entity @@ -69844,7 +69949,6 @@ - zone of skin @@ -69855,7 +69959,6 @@ - @@ -69951,7 +70054,6 @@ - organ @@ -70026,7 +70128,6 @@ - neuron projection bundle @@ -70036,7 +70137,6 @@ - neural nucleus @@ -70091,6 +70191,7 @@ + primitive urogenital sinus @@ -70100,6 +70201,7 @@ + mouth @@ -70172,6 +70274,8 @@ + + blood @@ -70190,6 +70294,7 @@ + blastula @@ -70275,7 +70380,6 @@ - material anatomical entity @@ -70322,7 +70426,6 @@ - acellular anatomical structure @@ -70535,7 +70638,6 @@ - @@ -70588,7 +70690,6 @@ - skeletal joint @@ -70599,17 +70700,6 @@ - - - - - - - - - - - reproductive system @@ -70618,6 +70708,7 @@ + gonad @@ -70638,16 +70729,6 @@ - - - - - - - - - - respiratory system @@ -70657,15 +70738,6 @@ - - - - - - - - - digestive system @@ -70684,14 +70756,6 @@ - - - - - - - - circulatory system @@ -70701,7 +70765,6 @@ - adipose tissue @@ -70720,14 +70783,8 @@ + - - - - - - - nervous system @@ -70773,6 +70830,7 @@ + hindgut @@ -70936,7 +70994,6 @@ - pectoral girdle region @@ -70964,13 +71021,6 @@ - - - - - - - skeletal system @@ -71000,7 +71050,6 @@ - lymphatic vessel @@ -71010,8 +71059,6 @@ - - bone element @@ -71020,6 +71067,7 @@ + digestive tract @@ -71090,7 +71138,6 @@ - @@ -71112,7 +71159,6 @@ - ciliary body @@ -71124,7 +71170,6 @@ - optic choroid @@ -71184,7 +71229,6 @@ - anterior segment of eyeball @@ -71312,7 +71356,6 @@ - blood vessel @@ -71396,6 +71439,7 @@ + postcranial axial skeleton @@ -71414,7 +71458,6 @@ - skin of body @@ -71500,6 +71543,7 @@ + vasculature of eye @@ -71512,11 +71556,6 @@ - - - - - musculoskeletal system @@ -71526,7 +71565,6 @@ - synovial joint @@ -71583,6 +71621,7 @@ + somite @@ -71625,7 +71664,6 @@ - muscle tissue @@ -71636,10 +71674,6 @@ - - - - hematopoietic system @@ -71648,6 +71682,7 @@ + lymph @@ -71658,9 +71693,6 @@ - - - immune system @@ -71671,8 +71703,6 @@ - - integumental system @@ -71711,7 +71741,6 @@ - bone tissue @@ -71806,6 +71835,8 @@ + + presomitic mesoderm @@ -71815,6 +71846,7 @@ + blood island @@ -71824,6 +71856,7 @@ + prechordal plate @@ -71833,6 +71866,7 @@ + intermediate mesoderm @@ -71842,6 +71876,7 @@ + axial mesoderm @@ -71897,6 +71932,7 @@ + @@ -71908,6 +71944,7 @@ + anterior neural tube @@ -71929,6 +71966,7 @@ + heart primordium @@ -71938,6 +71976,7 @@ + sclerotome @@ -72089,6 +72128,7 @@ + mesenchyme of lower jaw @@ -72269,6 +72309,7 @@ + head connective tissue @@ -72307,7 +72348,6 @@ - neural tissue @@ -72429,6 +72469,7 @@ + dermatome @@ -72475,6 +72516,7 @@ + endoderm-derived structure @@ -72484,6 +72526,7 @@ + mesoderm-derived structure @@ -72493,6 +72536,7 @@ + ectoderm-derived structure @@ -72522,6 +72566,7 @@ + cardiogenic plate @@ -72677,7 +72722,6 @@ - skeleton @@ -72686,6 +72730,7 @@ + dermomyotome @@ -72735,7 +72780,6 @@ - entire sense organ system @@ -72865,6 +72909,7 @@ + gastrula @@ -73393,6 +73438,7 @@ + mandibular prominence @@ -73412,6 +73458,7 @@ + axial skeleton plus cranial skeleton @@ -73761,7 +73808,6 @@ - nuclear complex of neuraxis @@ -73771,6 +73817,7 @@ + presumptive segmental plate @@ -73893,6 +73940,7 @@ + transudate @@ -74153,6 +74201,7 @@ + early telencephalic vesicle @@ -74259,6 +74308,7 @@ + future dermis @@ -74337,6 +74387,7 @@ + immature eye @@ -74365,6 +74416,7 @@ + germ layer / neural crest @@ -74560,6 +74612,7 @@ + postcranial axial skeletal system @@ -74753,7 +74806,6 @@ - dense connective tissue @@ -74789,7 +74841,6 @@ - anterior uvea @@ -75150,6 +75201,7 @@ + future central nervous system @@ -75224,7 +75276,6 @@ - @@ -75355,7 +75406,6 @@ - wall of blood vessel @@ -75580,468 +75630,470 @@ - + + + - CBL-mediated ubiquitination of CIN85 + SIAH1, SIAH2 ubiquitinate SNCAIP - Ubiquitination of cell cycle proteins targeted by the APC/C:Cdh1complex + SCF(beta-TrCP) ubiquitinates p-GLI2 - enabling an MF enables its parts + Ubiquitination of phosphorylated Cdc25A - PRKN polyubiquitinates RIPK3 + BIRC2/3 (cIAP1/2) is autoubiquitinated - TRAF2,6 ubiquitinates NLRC5 + ISGylation of host protein filamin B - SCF-beta-TRCP ubiquitinates p-7S-p100:RELB in active NIK:p-176,S180-IKKA dimer:p-7S-p100:SCF-beta-TRCP + effector input is compound function input - RNF41 ubiquitinates activated ERBB3 + inferring direct positive reg edge from input to regulatory subfunction - enabling an MF enables its parts + MIB2 ubiquitinates CYLD at K338, K530 - DDX58 is K63 polyubiquitinated + CHIP (STUB1) mediates ubiquitination of ERBB2 - BTRC:CUL1:SKP1 (SCF-beta-TrCP1) ubiquitinylates PER proteins + CBL binds and ubiquitinates phosphorylated Sprouty - DTX4 ubiquitinates p-S172-TBK1 within NLRP4:DTX4:STING:TBK1:IRF3 + Ubiquitination of Cyclin B by phospho-APC/C:Cdc20 complex - DTX4 ubiquitinates p-S172-TBK1 within NLRP4:DTX4:dsDNA:ZBP1:TBK1 + inferring direct positive reg edge from input to regulatory subfunction - Beta-TrCP ubiquitinates NFKB p50:p65:phospho IKBA complex + 'causally upstream of' and 'overlaps' should be disjoint properties (a SWRL rule is required because these are non-simple properties). - Ubiquitination of DLL/JAG ligands upon binding to NOTCH1 HD+PEST domain mutants + Input of effector is input of its parent MF - Pellino ubiquitinates IRAK1 + Ubiquitination of stimulated EGFR (CBL) - Autoubiquitination of phospho-COP1(Ser-387 ) + Defective NHLRC1 does not ubiquitinate EPM2A (laforin) and PPP1R3C (PTG) (type 2B disease) - Multiubiquitination of APC/C-associated Cdh1 + SMURF2 monoubiquitinates SMAD3 - VHL:EloB,C:NEDD8-CUL2:RBX1 complex ubiquitinylates HIF-alpha + Activated TRAF6 synthesizes unanchored polyubiquitin chains upon TLR3 stimulation - NHLRC1 mediated ubiquitination of EPM2A (laforin) and PPP1RC3 (PTG) associated with glycogen-GYG2 + K63-linked ubiquitination of RIP1 bound to the activated TLR complex - Ubiquitination of PAK-2p34 + DDX41 ubiquitination by TRIM21 - ERBB4 ubiquitination by WWP1/ITCH + TRAF6 polyubiquitinates NRIF - Ubiquitin-dependent degradation of the Smad complex terminates BMP2 signalling + Ubiquitin-dependent degradation of the SMAD complex terminates TGF-beta signaling - ISGylation of E2 conjugating enzymes + RNF41 ubiquitinates ERBB3 - Myristoylation of tBID by NMT1 + Activated TRAF6 synthesizes unanchored polyubiquitin chains upon TLR stimulation - RIP2 induces K63-linked ubiquitination of NEMO + Auto-ubiquitination of TRAF3 - RNF125 mediated ubiquitination of DDX58, IFIH1 and MAVS + Polyubiquitination of substrate - CBL neddylates TGFBR2 + MIB2 ubiquitinates CFLAR - Ubiquitination of p130 (RBL2) by SCF (Skp2) + Ubiquitination of NOTCH1 by ITCH in the absence of ligand - Ubiquitination of NICD1 by FBWX7 + CBL escapes CDC42-mediated inhibition by down-regulating the adaptor molecule Beta-Pix - SPATA2:CYLD-bound LUBAC ubiquitinates RIPK1 at K627 within the TNFR1 signaling complex + SIAH1:UBE2L6:Ubiquitin ubiquitinates SNCA - SCF betaTrCP ubiquitinates NFKB p105 within p-S927, S932-NFkB p105:TPL2:ABIN2 + Cytosolic VBC complex ubiquitinylates hydroxyprolyl-HIF-alpha - CUL5 mediates ubiquitination of ERBB2 + 'causally upstream of' and 'overlaps' should be disjoint properties (a SWRL rule is required because these are non-simple properties). - effector input is compound function input + cIAP1,2 ubiquitinates NIK in cIAP1,2:TRAF2::TRAF3:NIK - Ubiquitination of phosphorylated Cdc25A + Activation of ISG15 by UBA7 E1 ligase - BIRC2/3 (cIAP1/2) is autoubiquitinated + The geminin component of geminin:Cdt1 complexes is ubiquitinated, releasing Cdt1 - CHIP (STUB1) mediates ubiquitination of ERBB2 + Ubiquitination of DLL/JAG ligands upon binding to NOTCH1 HD+PEST domain mutants - CBL binds and ubiquitinates phosphorylated Sprouty + Pellino ubiquitinates IRAK1 - 'causally upstream of' and 'overlaps' should be disjoint properties (a SWRL rule is required because these are non-simple properties). + TRAF2,6 ubiquitinates NLRC5 - MIB2 ubiquitinates CYLD at K338, K530 + SCF-beta-TRCP ubiquitinates p-7S-p100:RELB in active NIK:p-176,S180-IKKA dimer:p-7S-p100:SCF-beta-TRCP - SIAH1, SIAH2 ubiquitinate SNCAIP + 'causally downstream of' and 'overlaps' should be disjoint properties (a SWRL rule is required because these are non-simple properties). - SCF(beta-TrCP) ubiquitinates p-GLI2 + SCF(beta-TrCP) ubiquitinates p-GLI1 - Nuclear VBC complex ubiquitinylates HIF-alpha + Ubiquitination of cell cycle proteins targeted by the APC/C:Cdh1complex - ARRB mediates NOTCH1 ubiquitination + PRKN polyubiquitinates RIPK3 - ISGylation of host protein filamin B + CBL-mediated ubiquitination of CIN85 if effector directly negatively regulates X, its parent MF directly negatively regulates X - TRAF6 ubiquitinqtes IRF7 within the activated TLR7/8 or 9 complex + ARRB mediates NOTCH1 ubiquitination - beta-TRCP ubiquitinates IkB-alpha in p-S32,33-IkB-alpha:NF-kB complex + Beta-TrCP ubiquitinates NFKB p50:p65:phospho IKBA complex - Activated TRAF6 synthesizes unanchored polyubiquitin chains upon ALPK1:ADP-heptose stimulation + Nuclear VBC complex ubiquitinylates HIF-alpha - Parkin promotes the ubiquitination of mitochondrial substrates + Multiubiquitination of APC/C-associated Cdh1 - RAF1:SGK:TSC22D3:WPP ubiquitinates SCNN channels + RNF41 ubiquitinates activated ERBB3 - Ubiquitination of Cyclin A by APC/C:Cdc20 complex + Autoubiquitination of phospho-COP1(Ser-387 ) - Ubiquitination of SKI/SKIL by RNF111/SMURF2 + DTX4 ubiquitinates p-S172-TBK1 within NLRP4:DTX4:STING:TBK1:IRF3 - 'causally downstream of' and 'overlaps' should be disjoint properties (a SWRL rule is required because these are non-simple properties). + DTX4 ubiquitinates p-S172-TBK1 within NLRP4:DTX4:dsDNA:ZBP1:TBK1 - Ubiquitination of stimulated EGFR (CBL) + DDX58 is K63 polyubiquitinated - Ubiquitination of Cyclin B by phospho-APC/C:Cdc20 complex + BTRC:CUL1:SKP1 (SCF-beta-TrCP1) ubiquitinylates PER proteins - if effector directly negatively regulates X, its parent MF directly negatively regulates X + Ubiquitination of p130 (RBL2) by SCF (Skp2) - The geminin component of geminin:Cdt1 complexes is ubiquitinated, releasing Cdt1 + Ubiquitination of SKI/SKIL by RNF111/SMURF2 - Polyubiquitination of substrate + 'causally downstream of' and 'overlaps' should be disjoint properties (a SWRL rule is required because these are non-simple properties). - MIB2 ubiquitinates CFLAR + Ubiquitination of Cyclin A by APC/C:Cdc20 complex - SIAH1:UBE2L6:Ubiquitin ubiquitinates SNCA + RAF1:SGK:TSC22D3:WPP ubiquitinates SCNN channels - SCF(beta-TrCP) ubiquitinates p-GLI1 + Parkin promotes the ubiquitination of mitochondrial substrates - cIAP1,2 ubiquitinates NIK in cIAP1,2:TRAF2::TRAF3:NIK + Activated TRAF6 synthesizes unanchored polyubiquitin chains upon ALPK1:ADP-heptose stimulation - Ubiquitination of NOTCH1 by ITCH in the absence of ligand + beta-TRCP ubiquitinates IkB-alpha in p-S32,33-IkB-alpha:NF-kB complex - CBL escapes CDC42-mediated inhibition by down-regulating the adaptor molecule Beta-Pix + TRAF6 ubiquitinqtes IRF7 within the activated TLR7/8 or 9 complex - involved in BP + ISGylation of E2 conjugating enzymes - Hh processing variants are ubiquitinated + Myristoylation of tBID by NMT1 - Ubiquitination of DLL/JAG ligands upon binding to NOTCH1 PEST domain mutants + ERBB4 ubiquitination by WWP1/ITCH - Activated TRAF6 synthesizes unanchored polyubiquitin chains upon TLR stimulation + Ubiquitin-dependent degradation of the Smad complex terminates BMP2 signalling - Auto-ubiquitination of TRAF3 + NHLRC1 mediated ubiquitination of EPM2A (laforin) and PPP1RC3 (PTG) associated with glycogen-GYG2 - Ubiquitination of CD4 by Vpu:CD4:beta-TrCP:SKP1 complex + Ubiquitination of PAK-2p34 - Ubiquitination of Emi1 by SCF-beta-TrCP + CBL neddylates TGFBR2 - ITCH polyubiquitinates MLKL at K50 + VHL:EloB,C:NEDD8-CUL2:RBX1 complex ubiquitinylates HIF-alpha - BRCA1:BARD1 heterodimer autoubiquitinates + inferring direct neg reg edge from input to regulatory subfunction - Ubiquitin-dependent degradation of the SMAD complex terminates TGF-beta signaling + RNF125 mediated ubiquitination of DDX58, IFIH1 and MAVS - RNF41 ubiquitinates ERBB3 + Ubiquitination of Securin by phospho-APC/C:Cdc20 complex - Activated TRAF6 synthesizes unanchored polyubiquitin chains upon TLR3 stimulation + RNF111 ubiquitinates SMAD7 - DDX41 ubiquitination by TRIM21 + BIRC(cIAP1/2) ubiquitinates RIPK1 - TRAF6 polyubiquitinates NRIF + Auto-ubiquitination of TRAF6 - Cytosolic VBC complex ubiquitinylates hydroxyprolyl-HIF-alpha + TRAF6 oligomer autoubiquitinates - involved in BP + Auto ubiquitination of TRAF6 bound to ALPK1:ADP-heptose:TIFA oligomer - effector input is compound function input + inferring direct reg edge from input to regulatory subfunction - K63-linked ubiquitination of RIP1 bound to the activated TLR complex + Auto ubiquitination of oligo-TRAF6 bound to p-IRAK2 at endosome membrane - Defective NHLRC1 does not ubiquitinate EPM2A (laforin) and PPP1R3C (PTG) (type 2B disease) + Ubiquitination of stimulated EGFR (CBL:GRB2) - SMURF2 monoubiquitinates SMAD3 + Multiubiquitination of Nek2A - Activation of ISG15 by UBA7 E1 ligase + SCF(beta-TrCP) ubiquitinates p-GLI3 - Auto-ubiquitination of TRAF3 within activated TLR3 complex + PARK2 K63-Ubiquitinates SNCAIP - Cdh1:APC/C ubiquitinates EHMT1 and EHMT2 + LUBAC ubiquitinates RIPK1 at K627 - Ubiquitination of DLL/JAG ligands upon binding to NOTCH2 + inferring direct reg edge from input to regulatory subfunction - STING ubiquitination by TRIM32 or TRIM56 + SPATA2:CYLD-bound LUBAC ubiquitinates RIPK1 at K627 within the TNFR1 signaling complex - Activated TRAF6 synthesizes unanchored polyubiquitin chains + CUL5 mediates ubiquitination of ERBB2 - Myristoylation of Nef + Ubiquitination of NICD1 by FBWX7 - Ubiquitination of NEMO by TRAF6 + RIP2 induces K63-linked ubiquitination of NEMO - ISGylation of host proteins + SCF betaTrCP ubiquitinates NFKB p105 within p-S927, S932-NFkB p105:TPL2:ABIN2 - ISGylation of viral protein NS1 + inferring direct neg reg edge from input to regulatory subfunction - infer input from direct reg + MIB2 ubiquitinates RIPK1 at K377, K604, K634 - TNFAIP3 (A20) ubiquitinates RIPK1 with K48-linked Ub chains + RAD18:UBE2B or RBX1:CUL4:DDB1:DTL monoubiquitinates PCNA - Ubiquitination of DLL/JAG ligands upon binding to NOTCH1 + Transfer of Ub from E2 to substrate and release of E2 - ITCH ubiquitinates DTX + K63polyUb-cIAP1,2 ubiquitinates TRAF3 - E1 mediated ubiquitin activation + NEDD4 ubiquitinates ERBB4jmAcyt1s80 dimer - FN3K phosphorylates ketosamines + Ubiquitination of phospho-p27/p21 - TRIM33 monoubiquitinates SMAD4 + Ubiquitination of Cyclin D1 - Input of effector is input of its parent MF + SKP1:FBXL5:CUL1:NEDD8 ubiquitinylates IREB2 - STUB1 ubiquitinates RIPK1 at K571, K604, K627 + ISGylation of IRF3 - RCHY1 monoubiquitinates POLH + FN3KRP phosphorylates PsiAm, RibAm - K63polyUb-TRAF6 ubiquitinates TAK1 + CBL ubiquitinates Sprouty - SKP1:FBXL5:CUL1:NEDD8 ubiquitinylates IREB2 + Input of effector is input of its parent MF - NEDD4 ubiquitinates ERBB4jmAcyt1s80 dimer + Auto-ubiquitination of TRAF6 - inferring direct neg reg edge from input to regulatory subfunction + ISGylation of protein phosphatase 1 beta (PP2CB) - Ubiquitination of phospho-p27/p21 + SMURFs/NEDD4L ubiquitinate phosphorylated TGFBR1 and SMAD7 - CBL ubiquitinates Sprouty + SCF-beta-TrCp1/2 ubiquitinates phosphorylated BORA - inferring direct reg edge from input to regulatory subfunction + NHLRC1 mediated ubiquitination of EPM2A and PPP1RC3 associated with glycogen-GYG1 - Transfer of Ub from E2 to substrate and release of E2 + infer input from direct reg - K63polyUb-cIAP1,2 ubiquitinates TRAF3 + Auto ubiquitination of oligo-TRAF6 bound to p-IRAK2 - MIB2 ubiquitinates RIPK1 at K377, K604, K634 + Ubiquitination of DLL/JAG ligands upon binding to NOTCH3 - RAD18:UBE2B or RBX1:CUL4:DDB1:DTL monoubiquitinates PCNA + K63-linked ubiquitination of RIP1 bound to the activated TLR complex - Ubiquitination of IKBKG by TRAF6 + if effector directly negatively regulates X, its parent MF directly negatively regulates X - STUB1 ubiquitinates RIPK3 at K55, K363 + Ubiquitination of NEMO by TRAF6 - SYVN1 ubiquitinates Hh C-terminal fragments + Ubiquitination of DLL/JAG ligands upon binding to NOTCH2 - Ubiquitination of DLL/JAG ligands upon binding to NOTCH1 HD domain mutants + STING ubiquitination by TRIM32 or TRIM56 - Multi-ubiquitination of APOBEC3G + involved in BP - Self-ubiquitination of RNF41 + Cdh1:APC/C ubiquitinates EHMT1 and EHMT2 - TRAF6 is K63 poly-ubiquitinated + Myristoylation of Nef - STUB1 (CHIP) ubiquitinates SMAD3 + Auto-ubiquitination of TRAF3 within activated TLR3 complex - inferring direct reg edge from input to regulatory subfunction + ISGylation of viral protein NS1 - SMURF2 ubiquitinates SMAD2 + FN3K phosphorylates ketosamines - Input of effector is input of its parent MF + ISGylation of host proteins - Auto ubiquitination of TRAF6 bound to ALPK1:ADP-heptose:TIFA oligomer + SMURF2 ubiquitinates SMAD2 - RNF111 ubiquitinates SMAD7 + STUB1 (CHIP) ubiquitinates SMAD3 - K63-linked ubiquitination of RIP1 bound to the activated TLR complex + effector input is compound function input - Auto ubiquitination of oligo-TRAF6 bound to p-IRAK2 + Ubiquitination of DLL/JAG ligands upon binding to NOTCH1 HD domain mutants - 'causally downstream of' and 'overlaps' should be disjoint properties (a SWRL rule is required because these are non-simple properties). + TRAF6 is K63 poly-ubiquitinated - BIRC(cIAP1/2) ubiquitinates RIPK1 + STUB1 ubiquitinates RIPK3 at K55, K363 - Auto-ubiquitination of TRAF6 + SYVN1 ubiquitinates Hh C-terminal fragments - Ubiquitination of Securin by phospho-APC/C:Cdc20 complex + Multi-ubiquitination of APOBEC3G - inferring direct positive reg edge from input to regulatory subfunction + Ubiquitination of IKBKG by TRAF6 - Ubiquitination of DLL/JAG ligands upon binding to NOTCH3 + Self-ubiquitination of RNF41 - NHLRC1 mediated ubiquitination of EPM2A and PPP1RC3 associated with glycogen-GYG1 + Activated TRAF6 synthesizes unanchored polyubiquitin chains - SMURFs/NEDD4L ubiquitinate phosphorylated TGFBR1 and SMAD7 + enabling an MF enables its parts - ISGylation of IRF3 + Ubiquitination of DLL/JAG ligands upon binding to NOTCH1 PEST domain mutants - FN3KRP phosphorylates PsiAm, RibAm + BRCA1:BARD1 heterodimer autoubiquitinates - Ubiquitination of Cyclin D1 + Hh processing variants are ubiquitinated - inferring direct neg reg edge from input to regulatory subfunction + Ubiquitination of Emi1 by SCF-beta-TrCP - SCF-beta-TrCp1/2 ubiquitinates phosphorylated BORA + ITCH polyubiquitinates MLKL at K50 - Auto-ubiquitination of TRAF6 + STUB1 ubiquitinates RIPK1 at K571, K604, K627 - ISGylation of protein phosphatase 1 beta (PP2CB) + ITCH ubiquitinates DTX - PARK2 K63-Ubiquitinates SNCAIP + E1 mediated ubiquitin activation - LUBAC ubiquitinates RIPK1 at K627 + involved in BP - inferring direct positive reg edge from input to regulatory subfunction + Ubiquitination of DLL/JAG ligands upon binding to NOTCH1 - Multiubiquitination of Nek2A + TRIM33 monoubiquitinates SMAD4 - SCF(beta-TrCP) ubiquitinates p-GLI3 + TNFAIP3 (A20) ubiquitinates RIPK1 with K48-linked Ub chains - Ubiquitination of stimulated EGFR (CBL:GRB2) + K63polyUb-TRAF6 ubiquitinates TAK1 - TRAF6 oligomer autoubiquitinates + Ubiquitination of CD4 by Vpu:CD4:beta-TrCP:SKP1 complex - Auto ubiquitination of oligo-TRAF6 bound to p-IRAK2 at endosome membrane + RCHY1 monoubiquitinates POLH - 'causally upstream of' and 'overlaps' should be disjoint properties (a SWRL rule is required because these are non-simple properties). + enabling an MF enables its parts @@ -76199,6 +76251,12 @@ Northwestern Thorn Scrub Forests + + glaciation + + + interglacial + Arctic front @@ -78775,42 +78833,6 @@ World Ocean - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -