diff --git a/runtime/bindings/python/tests/test_onnx/test_backend.py b/runtime/bindings/python/tests/test_onnx/test_backend.py
index 6fd59dd924c564..e20d0cc099aaad 100644
--- a/runtime/bindings/python/tests/test_onnx/test_backend.py
+++ b/runtime/bindings/python/tests/test_onnx/test_backend.py
@@ -333,6 +333,7 @@ def expect_fail(test_case_path, xfail):  # type: (str) -> None
     ),
     (
         xfail_issue_38722,
+        "OnnxBackendNodeModelTest.test_matmulinteger_cpu",
         "OnnxBackendNodeModelTest.test_qlinearmatmul_2D_cpu",
         "OnnxBackendNodeModelTest.test_qlinearmatmul_3D_cpu",
     ),