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Welcome to the mutation-signature-explorer-docker wiki!

This wiki contains information about running iMuSE locally.

A good place to start is on the Concepts page.

When running iMuSE locally, you will be able to customize:

• signatures, via the iMuSE Signatures Metadata File
• mutation data, via the iMuSE Mutation Data Metadata File
• pathways (as lists of genes assigned to those pathways), via the iMuSE Pathways Metadata File

The above metadata files tell iMuSE where to look in the obj directory for files. The wiki pages starting with "File Format:" in the sidebar to the right specify the file formats to which the above metadata files point.

Any files that are specified in the metadata files but that are not found by iMuSE are assumed to be hosted in the UMIACS object store, and will be downloaded when the iMuSE server docker container starts by automatically running this script. So any custom data files that are specified in the metadata files must already exist in the local obj directory when the container starts or else the script will erroneously attempt to download it from UMIACS and fail.