diff --git a/extensions/resteasy-reactive/rest-jackson/deployment/src/main/java/io/quarkus/resteasy/reactive/jackson/deployment/processor/JacksonDeserializerFactory.java b/extensions/resteasy-reactive/rest-jackson/deployment/src/main/java/io/quarkus/resteasy/reactive/jackson/deployment/processor/JacksonDeserializerFactory.java
index 73d843f80d00a..fa1fdb002bf0a 100644
--- a/extensions/resteasy-reactive/rest-jackson/deployment/src/main/java/io/quarkus/resteasy/reactive/jackson/deployment/processor/JacksonDeserializerFactory.java
+++ b/extensions/resteasy-reactive/rest-jackson/deployment/src/main/java/io/quarkus/resteasy/reactive/jackson/deployment/processor/JacksonDeserializerFactory.java
@@ -156,6 +156,9 @@
  *             Map.Entry entry = (Map.iterator) var3.next();
  *             String field = (String) entry.getKey();
  *             JsonNode jsonNode = (JsonNode) entry.getValue();
+ *             if (jsonNode.isNull()) {
+ *                 continue;
+ *             }
  *             switch (field) {
  *                 case "content":
  *                     dataItem.setContent(context.readTreeAsValue(jsonNode, this.valueTypes[0]));
@@ -240,10 +243,13 @@ private boolean deserializeObject(ClassInfo classInfo, ResultHandle objHandle, C
                 .invokeInterfaceMethod(ofMethod(Map.Entry.class, "getKey", Object.class), mapEntry);
         ResultHandle fieldValue = loopCreator.checkCast(loopCreator
                 .invokeInterfaceMethod(ofMethod(Map.Entry.class, "getValue", Object.class), mapEntry), JsonNode.class);
-        Switch.StringSwitch strSwitch = loopCreator.stringSwitch(fieldName);
+
+        loopCreator.ifTrue(loopCreator.invokeVirtualMethod(ofMethod(JsonNode.class, "isNull", boolean.class), fieldValue))
+                .trueBranch().continueScope(loopCreator);
 
         Set<String> deserializedFields = new HashSet<>();
         ResultHandle deserializationContext = deserialize.getMethodParam(1);
+        Switch.StringSwitch strSwitch = loopCreator.stringSwitch(fieldName);
         return deserializeFields(classCreator, classInfo, deserializationContext, objHandle, fieldValue, deserializedFields,
                 strSwitch, parseTypeParameters(classInfo, classCreator));
     }
diff --git a/extensions/resteasy-reactive/rest-jackson/deployment/src/test/java/io/quarkus/resteasy/reactive/jackson/deployment/test/SimpleJsonTest.java b/extensions/resteasy-reactive/rest-jackson/deployment/src/test/java/io/quarkus/resteasy/reactive/jackson/deployment/test/SimpleJsonTest.java
index 8aa2a009e8418..1c59ae89d210c 100644
--- a/extensions/resteasy-reactive/rest-jackson/deployment/src/test/java/io/quarkus/resteasy/reactive/jackson/deployment/test/SimpleJsonTest.java
+++ b/extensions/resteasy-reactive/rest-jackson/deployment/src/test/java/io/quarkus/resteasy/reactive/jackson/deployment/test/SimpleJsonTest.java
@@ -675,6 +675,24 @@ public void testEcho() {
                 .body("veterinarian.title", Matchers.nullValue());
     }
 
+    @Test
+    public void testEchoWithNullString() {
+        RestAssured
+                .with()
+                .body("{\"publicName\":null,\"veterinarian\":{\"name\":\"Dolittle\"},\"age\":5,\"vaccinated\":true}")
+                .contentType("application/json; charset=utf-8")
+                .post("/simple/dog-echo")
+                .then()
+                .statusCode(200)
+                .contentType("application/json")
+                .body("publicName", Matchers.nullValue())
+                .body("privateName", Matchers.nullValue())
+                .body("age", Matchers.is(5))
+                .body("vaccinated", Matchers.is(true))
+                .body("veterinarian.name", Matchers.is("Dolittle"))
+                .body("veterinarian.title", Matchers.nullValue());
+    }
+
     @Test
     public void testEchoWithMissingPrimitive() {
         RestAssured