diff --git a/CMakeLists.txt b/CMakeLists.txt
index 56ffea8d75..fc2b679214 100644
--- a/CMakeLists.txt
+++ b/CMakeLists.txt
@@ -153,6 +153,10 @@ else()
                         MbedTLS::mbedcrypto MbedTLS::mbedx509)
 endif()
 
+target_compile_definitions(LIB_LIEF PRIVATE
+  -DMBEDTLS_CONFIG_FILE="${CMAKE_CURRENT_SOURCE_DIR}/config/mbedtls/config.h"
+)
+
 if(WIN32 AND BUILD_SHARED_LIBS)
   target_link_libraries(LIB_LIEF PRIVATE ws2_32)
 endif()
diff --git a/config/mbedtls/config.h b/config/mbedtls/config.h
new file mode 100644
index 0000000000..1007c99aee
--- /dev/null
+++ b/config/mbedtls/config.h
@@ -0,0 +1,5 @@
+#include "mbedtls/mbedtls_config.h"
+
+#if defined (MBEDTLS_ARCH_IS_X86)
+#undef MBEDTLS_AESNI_C
+#endif