diff --git a/pkg/transparentproxy/config/config.go b/pkg/transparentproxy/config/config.go
index ee3c0867c640..2ce67bfe9f0d 100644
--- a/pkg/transparentproxy/config/config.go
+++ b/pkg/transparentproxy/config/config.go
@@ -69,11 +69,14 @@ type TrafficFlow struct {
 }
 
 type DNS struct {
-	Enabled            bool
-	CaptureAll         bool
-	Port               uint16
-	ConntrackZoneSplit bool
-	ResolvConfigPath   string
+	Enabled             bool
+	CaptureAll          bool
+	Port                uint16
+	// The iptables chain where the upstream DNS requests should be directed to.
+	// It is only applied for IP V4. Use with care. (default "RETURN")
+	UpstreamTargetChain string
+	ConntrackZoneSplit  bool
+	ResolvConfigPath    string
 }
 
 type VNet struct {
@@ -153,6 +156,13 @@ func (c Config) ShouldRedirectDNS() bool {
 	return c.Redirect.DNS.Enabled
 }
 
+// ShouldFallbackDNSToUpstreamChain is just a convenience function which can be used in
+// iptables conditional command generations instead of inlining anonymous functions
+// i.e. AppendIf(ShouldFallbackDNSToUpstreamChain, Match(...), Jump(Drop()))
+func (c Config) ShouldFallbackDNSToUpstreamChain() bool {
+	return c.Redirect.DNS.UpstreamTargetChain != ""
+}
+
 // ShouldCaptureAllDNS is just a convenience function which can be used in
 // iptables conditional command generations instead of inlining anonymous functions
 // i.e. AppendIf(ShouldCaptureAllDNS, Match(...), Jump(Drop()))
@@ -309,6 +319,10 @@ func MergeConfigWithDefaults(cfg Config) Config {
 		result.Redirect.DNS.ResolvConfigPath = cfg.Redirect.DNS.ResolvConfigPath
 	}
 
+	if cfg.Redirect.DNS.UpstreamTargetChain != "" {
+		result.Redirect.DNS.UpstreamTargetChain = cfg.Redirect.DNS.UpstreamTargetChain
+	}
+
 	if cfg.Redirect.DNS.Port != 0 {
 		result.Redirect.DNS.Port = cfg.Redirect.DNS.Port
 	}
diff --git a/pkg/transparentproxy/iptables/builder/builder_nat.go b/pkg/transparentproxy/iptables/builder/builder_nat.go
index 0aa75323bdbe..7c85430661bf 100644
--- a/pkg/transparentproxy/iptables/builder/builder_nat.go
+++ b/pkg/transparentproxy/iptables/builder/builder_nat.go
@@ -225,13 +225,19 @@ func addOutputRules(cfg config.Config, dnsServers []string, nat *table.NatTable)
 	}
 
 	if cfg.ShouldRedirectDNS() {
+		jumpTarget := Return()
+		if cfg.ShouldFallbackDNSToUpstreamChain() {
+			jumpTarget = ToUserDefinedChain(cfg.Redirect.DNS.UpstreamTargetChain)
+		}
+
 		nat.Output().Insert(
 			rulePosition,
 			Protocol(Udp(DestinationPort(DNSPort))),
 			Match(Owner(Uid(uid))),
-			Jump(Return()),
+			Jump(jumpTarget),
 		)
 		rulePosition++
+
 		if cfg.ShouldCaptureAllDNS() {
 			nat.Output().Insert(
 				rulePosition,
diff --git a/pkg/transparentproxy/transparentproxy_experimental.go b/pkg/transparentproxy/transparentproxy_experimental.go
index 344fce1a7efb..7af7e8b98ba9 100644
--- a/pkg/transparentproxy/transparentproxy_experimental.go
+++ b/pkg/transparentproxy/transparentproxy_experimental.go
@@ -161,10 +161,11 @@ func (tp *ExperimentalTransparentProxy) Setup(tpConfig *config.TransparentProxyC
 				ExcludePortsForUIDs: excludePortsForUIDs,
 			},
 			DNS: config.DNS{
-				Enabled:            tpConfig.RedirectDNS,
-				CaptureAll:         tpConfig.RedirectAllDNSTraffic,
-				Port:               agentDNSListenerPort,
-				ConntrackZoneSplit: !tpConfig.SkipDNSConntrackZoneSplit,
+				Enabled:             tpConfig.RedirectDNS,
+				CaptureAll:          tpConfig.RedirectAllDNSTraffic,
+				Port:                agentDNSListenerPort,
+				UpstreamTargetChain: tpConfig.DNSUpstreamTargetChain,
+				ConntrackZoneSplit:  !tpConfig.SkipDNSConntrackZoneSplit,
 			},
 			VNet: config.VNet{
 				Networks: tpConfig.VnetNetworks,
diff --git a/test/framework/universal_app.go b/test/framework/universal_app.go
index 427a90a846e9..aea0aff62cd5 100644
--- a/test/framework/universal_app.go
+++ b/test/framework/universal_app.go
@@ -490,6 +490,7 @@ func (s *UniversalApp) setupTransparent(cpIp string, builtindns bool, experiment
 	if builtindns {
 		args = append(args,
 			"--redirect-dns",
+			"--redirect-dns-upstream-target-chain", "DOCKER_OUTPUT",
 		)
 	}