Function slingshot no possibility to create graph

[Capiques]

Hello,

I have an issue when I want to use slingshot, my data is composed of 4261 cells et 31254 genes. Matrix of 31254x4261; I have two conditions, I want after using slingshot use condiments.

but I have an error when I run my command :

sce_pdt <- slingshot( sce_pdt, reducedDim = "UMAP", clusterLabels = sce_pdt$short_name)
Error in graph.adjacency.dense(adjmatrix, mode = mode, weighted = weighted, :
At vendor/cigraph/src/constructors/adjacency.c:538 : Adjacency matrix should be symmetric to produce an undirected graph. Invalid value

When I run without giving another cluster label it's working, so I don't know. Does slingshot need a minimum of cell per cluster?

Thanks!!!

Best

[kstreet13]

I think you're probably correct that it is an issue with small clusters. Other users have had similar issues and they seemed to be resolved by removing/merging any clusters consisting of a single cell. Let me know if that doesn't work!