diff --git a/.github/CODEOWNERS b/.github/CODEOWNERS
index 51fba3f61278c..4647c2ede6ae0 100644
--- a/.github/CODEOWNERS
+++ b/.github/CODEOWNERS
@@ -607,6 +607,7 @@
 /test/new-e2e/tests/language-detection        @DataDog/processes
 /test/new-e2e/tests/ndm                       @DataDog/ndm-core
 /test/new-e2e/tests/ndm/netflow               @DataDog/ndm-integrations
+/test/new-e2e/tests/netpath                   @DataDog/Networks @DataDog/network-device-monitoring
 /test/new-e2e/tests/npm                       @DataDog/Networks
 /test/new-e2e/tests/npm/ec2_1host_wkit_test.go @DataDog/Networks @DataDog/windows-kernel-integrations
 /test/new-e2e/tests/orchestrator              @DataDog/container-app
diff --git a/.gitlab-ci.yml b/.gitlab-ci.yml
index abfece6aac73b..67afb78dc55d8 100644
--- a/.gitlab-ci.yml
+++ b/.gitlab-ci.yml
@@ -981,6 +981,16 @@ workflow:
       compare_to: main # TODO: use a variable, when this is supported https://gitlab.com/gitlab-org/gitlab/-/issues/369916
     when: on_success
 
+.on_netpath_or_e2e_changes:
+  - !reference [.on_e2e_main_release_or_rc]
+  - changes:
+      paths:
+        - pkg/collector/corechecks/networkpath/**/*
+        - test/new-e2e/tests/netpath/**/*
+        - test/new-e2e/go.mod
+      compare_to: main # TODO: use a variable, when this is supported https://gitlab.com/gitlab-org/gitlab/-/issues/369916
+    when: on_success
+
 .on_otel_or_e2e_changes:
   - !reference [.on_e2e_main_release_or_rc]
   - changes:
diff --git a/.gitlab/e2e/e2e.yml b/.gitlab/e2e/e2e.yml
index 6064179b1069b..c62f11a8165e2 100644
--- a/.gitlab/e2e/e2e.yml
+++ b/.gitlab/e2e/e2e.yml
@@ -511,6 +511,15 @@ new-e2e-ha-agent:
     TARGETS: ./tests/ha-agent
     TEAM: ndm-core
 
+new-e2e-netpath:
+  extends: .new_e2e_template_needs_deb_x64
+  rules:
+    - !reference [.on_netpath_or_e2e_changes]
+    - !reference [.manual]
+  variables:
+    TARGETS: ./tests/netpath
+    TEAM: network-performance-monitoring
+
 new-e2e-windows-systemprobe:
   extends: .new_e2e_template
   rules:
diff --git a/test/new-e2e/tests/netpath/network_path_integration_test.go b/test/new-e2e/tests/netpath/network_path_integration_test.go
new file mode 100644
index 0000000000000..d93729d413f7a
--- /dev/null
+++ b/test/new-e2e/tests/netpath/network_path_integration_test.go
@@ -0,0 +1,88 @@
+// Unless explicitly stated otherwise all files in this repository are licensed
+// under the Apache License Version 2.0.
+// This product includes software developed at Datadog (https://www.datadoghq.com/).
+// Copyright 2016-present Datadog, Inc.
+
+// Package netpath contains e2e tests for Network Path Integration feature
+package netpath
+
+import (
+	_ "embed"
+	"fmt"
+	"testing"
+	"time"
+
+	"github.com/DataDog/datadog-agent/test/fakeintake/aggregator"
+	fakeintakeclient "github.com/DataDog/datadog-agent/test/fakeintake/client"
+	"github.com/DataDog/test-infra-definitions/components/datadog/agentparams"
+	"github.com/stretchr/testify/assert"
+	"github.com/stretchr/testify/require"
+
+	"github.com/DataDog/datadog-agent/test/new-e2e/pkg/e2e"
+	"github.com/DataDog/datadog-agent/test/new-e2e/pkg/environments"
+	awshost "github.com/DataDog/datadog-agent/test/new-e2e/pkg/environments/aws/host"
+)
+
+type networkPathIntegrationTestSuite struct {
+	e2e.BaseSuite[environments.Host]
+}
+
+// TestNetworkPathIntegrationSuite runs the Network Path Integration e2e suite
+func TestNetworkPathIntegrationSuite(t *testing.T) {
+	// language=yaml
+	sysProbeConfig := `
+traceroute:
+  enabled: true
+`
+
+	// language=yaml
+	networkPathIntegration := `
+instances:
+- hostname: api.datadoghq.eu
+  protocol: TCP
+  port: 443
+- hostname: 8.8.8.8
+  protocol: UDP
+`
+
+	e2e.Run(t, &networkPathIntegrationTestSuite{}, e2e.WithProvisioner(awshost.Provisioner(
+		awshost.WithAgentOptions(
+			agentparams.WithSystemProbeConfig(sysProbeConfig),
+			agentparams.WithIntegration("network_path.d", networkPathIntegration),
+		)),
+	))
+}
+
+func (s *networkPathIntegrationTestSuite) TestNetworkPathIntegrationMetrics() {
+	fakeClient := s.Env().FakeIntake.Client()
+
+	s.EventuallyWithT(func(c *assert.CollectT) {
+		s.T().Log("try assert datadog.network_path.path.monitored metric")
+		metrics, err := fakeClient.FilterMetrics("datadog.network_path.path.monitored")
+		require.NoError(c, err)
+		assert.NotEmpty(c, metrics)
+		for _, metric := range metrics {
+			s.T().Logf("    datadog.network_path.path.monitored metric tags: %+v", metric.Tags)
+		}
+
+		destinationsTagsToAssert := [][]string{
+			{"destination_hostname:api.datadoghq.eu", "protocol:TCP", "destination_port:443"},
+			{"destination_hostname:8.8.8.8", "protocol:UDP"},
+		}
+		for _, tags := range destinationsTagsToAssert {
+			// assert destination is monitored
+			metrics, err = fakeClient.FilterMetrics("datadog.network_path.path.monitored", fakeintakeclient.WithTags[*aggregator.MetricSeries](tags))
+			assert.NoError(c, err)
+			assert.NotEmpty(c, metrics, fmt.Sprintf("metric with tags `%v` not found", tags))
+
+			// assert hops
+			metrics, err = fakeClient.FilterMetrics("datadog.network_path.path.hops",
+				fakeintakeclient.WithTags[*aggregator.MetricSeries](tags),
+				fakeintakeclient.WithMetricValueHigherThan(0),
+			)
+			assert.NoError(c, err)
+			assert.NotEmpty(c, metrics, fmt.Sprintf("metric with tags `%v` not found", tags))
+
+		}
+	}, 5*time.Minute, 3*time.Second)
+}