diff --git a/.github/workflows/test.yaml b/.github/workflows/test.yaml
index acc7db31..fbe76a9b 100644
--- a/.github/workflows/test.yaml
+++ b/.github/workflows/test.yaml
@@ -65,11 +65,11 @@ jobs:
     - name: Install package and run software tests (Python 3.6)
       if: matrix.python-version == '3.6'
       run: |
-        pip install '.[graphql,develop,test]'
+        pip install '.[cli,graphql,develop,test]'
         poe test
 
     - name: Install and completely validate package (Python >=3.6)
       if: matrix.python-version != '3.6'
       run: |
-        uv pip install '.[graphql,develop,test]' --system
+        uv pip install '.[cli,graphql,develop,test]' --system
         poe check
diff --git a/README.md b/README.md
index 9df88d5f..b2a08d2f 100644
--- a/README.md
+++ b/README.md
@@ -42,7 +42,11 @@ for more details on features available in Responder.
 
 Install the most recent stable release:
 
-    pip install --upgrade responder
+    pip install --upgrade 'responder'
+
+Install package including CLI interface and GraphQL extension:
+
+    pip install --upgrade 'responder[cli,graphql]'
 
 Or, install directly from the repository:
 
diff --git a/responder/cli.py b/responder/cli.py
new file mode 100644
index 00000000..d9e5e5e1
--- /dev/null
+++ b/responder/cli.py
@@ -0,0 +1,46 @@
+"""Responder.
+
+Usage:
+  responder
+  responder run [--build] <module>
+  responder build
+  responder --version
+
+Options:
+  -h --help     Show this screen.
+  -v --version  Show version.
+
+"""
+
+import subprocess
+
+import docopt
+
+from .__version__ import __version__
+
+
+def cli():
+    """
+    CLI interface handler of the Responder package.
+    """
+    args = docopt.docopt(__doc__, argv=None, version=__version__, options_first=False)
+
+    module = args["<module>"]
+    build = args["build"] or args["--build"]
+    run = args["run"]
+
+    if build:
+        # S603, S607 are suppressed as we're using fixed arguments, not user input
+        subprocess.check_call(["npm", "run", "build"])  # noqa: S603, S607
+
+    if run:
+        split_module = module.split(":")
+
+        if len(split_module) > 1:
+            module = split_module[0]
+            prop = split_module[1]
+        else:
+            prop = "api"
+
+        app = __import__(module)
+        getattr(app, prop).run()
diff --git a/setup.py b/setup.py
index cd4c4526..95afaf77 100644
--- a/setup.py
+++ b/setup.py
@@ -112,10 +112,12 @@ def run(self):
     url="https://github.com/kennethreitz/responder",
     packages=find_packages(exclude=["tests"]),
     package_data={},
+    entry_points={"console_scripts": ["responder=responder.cli:cli"]},
     python_requires=">=3.6",
     setup_requires=[],
     install_requires=required,
     extras_require={
+        "cli": ["docopt-ng"],
         "develop": [
             "poethepoet",
             "pyproject-fmt; python_version>='3.7'",
diff --git a/tests/test_cli.py b/tests/test_cli.py
new file mode 100644
index 00000000..5975105a
--- /dev/null
+++ b/tests/test_cli.py
@@ -0,0 +1,18 @@
+import subprocess
+
+import pytest
+
+from responder.__version__ import __version__
+
+pytest.importorskip("docopt", reason="docopt-ng package not installed")
+
+
+def test_cli_version(capfd):
+    # S603, S607 are suppressed as we're using fixed arguments, not user input
+    try:
+        subprocess.check_call(["responder", "--version"])  # noqa: S603, S607
+    except subprocess.CalledProcessError as ex:
+        pytest.fail(f"CLI command failed with exit code {ex.returncode}")
+
+    stdout = capfd.readouterr().out.strip()
+    assert stdout == __version__