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allow users to design a vector and match any backbone in the databases. insert specific, backbone agnostic
The text was updated successfully, but these errors were encountered:
jjti
changed the title
Allow for reverse/feature engineering without a specified backbone
reverse/feature engineering without a specified backbone
Feb 19, 2019
jjti
changed the title
reverse/feature engineering without a specified backbone
sequence/feature design without a specified backbone
Feb 19, 2019
Could do this by putting in a mock backbone (random 3kbp sequence). It will be synthesized. then check the first and last fragment of each assembly (before filling) and see whether either is part of a vector in their database/match. If they are, use that backbone (extend that first/last frag), remove the random sequence, and fill
note: this probably won't always lead to the best solutions
allow users to design a vector and match any backbone in the databases. insert specific, backbone agnostic
The text was updated successfully, but these errors were encountered: