From 9c72c8558757aa0922458262a16dcf2b65c3e600 Mon Sep 17 00:00:00 2001 From: Du Jinhong <413075930@qq.com> Date: Tue, 26 Sep 2023 19:07:01 -0400 Subject: [PATCH] Update README.md --- README.md | 12 ++++++------ 1 file changed, 6 insertions(+), 6 deletions(-) diff --git a/README.md b/README.md index b1071aa..d29b8c4 100644 --- a/README.md +++ b/README.md @@ -5,7 +5,7 @@ # Joint Trajectory Inference for Single-cell Genomics Using Deep Learning with a Mixture Prior -This is a Python package, VITAE, to perform trajectory inference for single-cell RNA sequencing (scRNA-seq). VITAE is a probabilistic method combining a latent hierarchical mixture model with variational autoencoders to infer trajectories from posterior approximations. VITAE is computationally scalable and can adjust for confounding covariates to learn a shared trajectory from multiple datasets. VITAE also provides uncertainty quantification of the inferred trajectory and cell positions, and can find differentially expressed genes along the trajectory. For more information, please check out our [manuscript on bioRXiv](https://www.biorxiv.org/content/10.1101/2020.12.26.424452v3). +This is a Python package, VITAE, to perform trajectory inference for single-cell RNA sequencing (scRNA-seq). VITAE is a probabilistic method combining a latent hierarchical mixture model with variational autoencoders to infer trajectories from posterior approximations. VITAE is computationally scalable and can adjust for confounding covariates to learn a shared trajectory from multiple datasets. VITAE also provides uncertainty quantification of the inferred trajectory and cell positions and can find differentially expressed genes along the trajectory. For more information, please check out our [manuscript on bioRXiv](https://www.biorxiv.org/content/10.1101/2020.12.26.424452v3). ## Tutorials @@ -17,25 +17,25 @@ notebook | system | details | reference [*tutorial\_dentate*](https://github.com/jaydu1/VITAE/blob/master/tutorials/tutorial_dentate.ipynb) | neurons | 3585 cells and 2182 genes, 10x Genomics | [Hochgerner *et al.* (2018)](https://doi.org/10.1038/s41593-017-0056-2) [*tutorial\_mouse\_brain*](https://github.com/jaydu1/VITAE/blob/master/tutorials/tutorial_mouse_brain.ipynb) | neurons | 16651 cells and 14707 genes | [Yuzwa *et al.* (2017)](https://doi.org/10.1016/j.celrep.2017.12.017),
[Ruan *et al.* (2021)](https://doi.org/10.1073/pnas.2018866118) -In case github rendering stops working, [NbViewer](https://nbviewer.jupyter.org/) is an alternative online tool to render Jupyter Notebooks. +In case GitHub rendering stops working, [NbViewer](https://nbviewer.jupyter.org/) is an alternative online tool to render Jupyter Notebooks. [Datasets](https://github.com/jaydu1/VITAE/tree/master/data) and [Documents](https://jaydu1.github.io/VITAE/) are availble. ## Dependency -Our Python package is available on PyPI and the user can install the CPU version with the following command. To enable GPU for Tensorflow, one should install CUDA dependencies and `tensorflow-gpu` package. We also recommend to use `conda`, `miniconda` or `virtualenv` to manage Python environment and install the package in a new environment. +Our Python package is available on PyPI and the user can install the CPU version with the following command: ``` >> pip install pyvitae ``` - -After installing all required packages, one can open the Jupyter Notebook via terminal: +To enable GPU for TensorFlow, one should install CUDA dependencies and the `tensorflow-gpu` package. We also recommend using `conda`, `miniconda`, or `virtualenv` to manage the Python environment and install the package in a new environment. +After installing all required packages, one can open the Jupyter Notebook via the terminal: ``` >>> jupyter notebook ``` -The required tensorflow versions are: +The required TensorFlow versions are: Package|Version ---|---