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Merge read pairs #93

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atduggan opened this issue Aug 17, 2020 · 0 comments
Open

Merge read pairs #93

atduggan opened this issue Aug 17, 2020 · 0 comments

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@atduggan
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Would it be possible to include a step that merges overlapping R1/R2 pairs such that all reads considered for variant calling and coverage estimates are independent? A test on data from the artic primer scheme indicated that almost 100% of reads could be merged and even with the longer resende primer scheme >50% of reads could be merged by Flash.

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