diff --git a/.github/workflows/nano_howto_guides_tests.yml b/.github/workflows/nano_howto_guides_tests.yml
new file mode 100644
index 000000000000..4e023241c176
--- /dev/null
+++ b/.github/workflows/nano_howto_guides_tests.yml
@@ -0,0 +1,50 @@
+name: Nano Unit Tests for How-To Guides Notebooks
+
+on:
+  # Triggers the workflow on push or pull request events but only for the main branch
+  push:
+    branches: [ main ]
+  pull_request:
+    branches: [ main ]
+    paths:
+      #- 'python/nano/**'
+      - '.github/workflows/nano_howto_guides_tests.yml'
+
+# A workflow run is made up of one or more jobs that can run sequentially or in parallel
+jobs:
+  nano-howto-guides-inference-test:
+    # The type of runner that the job will run on
+    runs-on: ${{ matrix.os }}
+    strategy:
+      fail-fast: false
+      matrix:
+        os: ["ubuntu-20.04"]
+        python-version: ["3.7"]
+
+    # Steps represent a sequence of tasks that will be executed as part of the job
+    steps:
+      # Checks-out your repository under $GITHUB_WORKSPACE, so your job can access it
+      - uses: actions/checkout@v2
+      - name: Set up Python ${{ matrix.python-version }}
+        uses: actions/setup-python@v2
+        with:
+          python-version: ${{ matrix.python-version }}
+      - name: Install dependencies
+        run: |
+          python -m pip install --upgrade pip
+          python -m pip install --upgrade setuptools==58.0.4
+          python -m pip install --upgrade wheel
+      
+      - name: Run unit tests for Inference PyTorch how-to guides
+        shell: bash
+        run: |
+            $CONDA/bin/conda create -n howto-guides-inference-pytorch -y python==3.7.10 setuptools=58.0.4
+            source $CONDA/bin/activate howto-guides-inference-pytorch
+            $CONDA/bin/conda info
+            bash python/nano/dev/build_and_install.sh linux default false pytorch
+            source bigdl-nano-init
+            bash python/nano/tutorial/notebook/inference/pytorch/run-nano-howto-guides-inference-pytorch-tests.sh
+            source $CONDA/bin/deactivate
+            $CONDA/bin/conda remove -n howto-guides-inference-pytorch --all
+        env:
+            ANALYTICS_ZOO_ROOT: ${{ github.workspace }}
\ No newline at end of file
diff --git a/python/nano/tutorial/notebook/inference/pytorch/run-nano-howto-guides-inference-pytorch-tests.sh b/python/nano/tutorial/notebook/inference/pytorch/run-nano-howto-guides-inference-pytorch-tests.sh
new file mode 100644
index 000000000000..79dc52e14dcf
--- /dev/null
+++ b/python/nano/tutorial/notebook/inference/pytorch/run-nano-howto-guides-inference-pytorch-tests.sh
@@ -0,0 +1,24 @@
+#!/bin/bash
+
+# export ANALYTICS_ZOO_ROOT=${ANALYTICS_ZOO_ROOT}
+# export NANO_HOME=${ANALYTICS_ZOO_ROOT}/python/nano/src
+export NANO_HOWTO_GUIDES_TEST_DIR=${ANALYTICS_ZOO_ROOT}/python/nano/tutorial/notebook/inference/pytorch
+
+set -e
+
+# the number of batches to run is limited for testing purposes
+sed -i 's/Trainer(max_epochs=1)/Trainer(max_epochs=1, fast_dev_run=True)/' $NANO_HOWTO_GUIDES_TEST_DIR/quantize_pytorch_inference_inc.ipynb $NANO_HOWTO_GUIDES_TEST_DIR/quantize_pytorch_inference_pot.ipynb
+
+# comment out the install command for bigdl-nano[pytorch]
+sed -i 's/!pip install --pre --upgrade bigdl-nano\[pytorch]/#!pip install --pre --upgrade bigdl-nano[pytorch]/' $NANO_HOWTO_GUIDES_TEST_DIR/*
+
+echo "Start testing"
+start=$(date "+%s")
+
+python -m pytest -s --nbmake --nbmake-timeout=600 --nbmake-kernel=python3 ${NANO_HOWTO_GUIDES_TEST_DIR}
+
+now=$(date "+%s")
+time=$((now-start))
+
+echo "BigDL-Nano how-to guides tests finished."
+echo "Time used: $time seconds"