diff --git a/ibis/formats/pandas.py b/ibis/formats/pandas.py
index ea67c9ad7537..a1ea9ea82489 100644
--- a/ibis/formats/pandas.py
+++ b/ibis/formats/pandas.py
@@ -383,6 +383,8 @@ def convert(value):
                 return value
             elif isinstance(value, UUID):
                 return value
+            elif isinstance(value, bytes):
+                return UUID(bytes=value)
             return UUID(value)
 
         return convert