diff --git a/.changelog/34737.txt b/.changelog/34737.txt
new file mode 100644
index 00000000000..d916ee79011
--- /dev/null
+++ b/.changelog/34737.txt
@@ -0,0 +1,3 @@
+```release-note:bug
+resource/aws_glue_connection: Fix crash while creating resource with empty `physical_connection_requirements` configuration block
+```
diff --git a/internal/service/glue/connection.go b/internal/service/glue/connection.go
index cb934e2511a..cccb2efc8d5 100644
--- a/internal/service/glue/connection.go
+++ b/internal/service/glue/connection.go
@@ -277,9 +277,8 @@ func expandConnectionInput(d *schema.ResourceData) *glue.ConnectionInput {
 		connectionInput.MatchCriteria = flex.ExpandStringList(v.([]interface{}))
 	}
 
-	if v, ok := d.GetOk("physical_connection_requirements"); ok {
-		physicalConnectionRequirementsList := v.([]interface{})
-		physicalConnectionRequirementsMap := physicalConnectionRequirementsList[0].(map[string]interface{})
+	if v, ok := d.GetOk("physical_connection_requirements"); ok && v.([]interface{})[0] != nil {
+		physicalConnectionRequirementsMap := v.([]interface{})[0].(map[string]interface{})
 		connectionInput.PhysicalConnectionRequirements = expandPhysicalConnectionRequirements(physicalConnectionRequirementsMap)
 	}