From e0e4dab60ddec8a119b6954e82829cf1434d5c0d Mon Sep 17 00:00:00 2001 From: AriaAgarwal Date: Thu, 3 Oct 2024 17:48:57 -0400 Subject: [PATCH] Add blurbs to INDRA html tabs --- .../protein_analysis_template.html | 24 + notebooks/beta_catenin_dou/results.html | 1262 ++++++----------- 2 files changed, 451 insertions(+), 835 deletions(-) diff --git a/notebooks/beta_catenin_dou/protein_analysis_template.html b/notebooks/beta_catenin_dou/protein_analysis_template.html index bdb6fcba8..2143b6e8a 100644 --- a/notebooks/beta_catenin_dou/protein_analysis_template.html +++ b/notebooks/beta_catenin_dou/protein_analysis_template.html @@ -42,6 +42,11 @@

Protein Analysis Results

INDRA Statements with Evidences

+

+ INDRA was used to automatically assemble a comprehensive set of statements with evidences to detail the + interactions between the source and target proteins by extracting information from scientific literature and + curated databases. +

{% for html_page in result['indra_stmt_html_contents'] %} {{ html_page | safe }} {% endfor %} @@ -58,22 +63,41 @@

Bar Charts

Shared Families

+

+ Shared protein families are derived using cypher queries to assess the hierarchical relationships + within the INDRA knowledge base, specifically examining "isa" and "partof" relationships to determine + protein family complexes between the source and target proteins. +

{{ result['shared_families'] | safe }}

Shared Upstream Bioentities from Target Proteins

+

+ Shared upstream bioentites explore the intersections between the upstream bioentities of the target proteins + and the bioentities that the target proteins have a direct INDRA relationship with. +

{{ result['upstream_entities'] | safe }}

Boxplots for Shared Go Terms and Bioentities

Stats Boxplot

Shared Pathways Between Source and Enriched Targets Set

+

+ The shared pathways analysis determines the shared Reactome and WikiPathways between the source and + target proteins to reveal potential functional overlaps and shared biological processes through pathway + membership. +

{{ result['shared_pathways'] | safe }}

Bar Chart for Frequency of Shared Pathways by Protein

Pathways Chart

Shared Go Terms Between Gene Sets

+

+ The shared GO terms analysis utlizes Gene Ontology (GO) terms associated with the source and target + proteins by finding the intersection of GO terms to explore commonalities in molecular functions, + biological processes, or cellular locations. +

{{ result['shared_go_terms'] | safe }}
diff --git a/notebooks/beta_catenin_dou/results.html b/notebooks/beta_catenin_dou/results.html index abd91cb53..44f39570e 100644 --- a/notebooks/beta_catenin_dou/results.html +++ b/notebooks/beta_catenin_dou/results.html @@ -52,6 +52,11 @@

Protein Analysis Results

INDRA Statements with Evidences

+

+ INDRA was used to automatically assemble a comprehensive set of statements with evidences to detail the + interactions between the source and target proteins by extracting information from scientific literature and + curated databases. +

@@ -116,56 +121,14 @@

INDRA Statements with Evidences

padding-right: 1em; } - /* The footer */ - .footer { - position: fixed; /* Make sure the footer is always visible at the bottom */ - bottom: 0; /* Stick it to the bottom of the page */ - left: 0; - right: 20em; - color: #606060; - text-align: left; - padding: 0.5em; - box-shadow: 0 -2px 10px rgba(0, 0, 0, 0.1); - height: 65; - } - - .footer h4, .footer p, .footer a { - font-size: 9pt; - line-height: 1.3; - margin: 0; /* Reduces vertical spacing */ - } - - .side-info-block { - padding: 0em 8px 0em 8px; - margin-bottom: 0; - } - - /* Footer links */ - .il-nav-link { - display: block; - margin: 5px 0; - color: #256DC5; /* Blue color */ - text-decoration: none; - } - - .il-nav-link:hover { - text-decoration: underline; - color: #007bff; - } - - #about-this-project p, #about-this-project a { - font-size: 9pt; - margin-bottom: 0; + .left { + width: 20em; + left: 0; } .right { - width: 20em; /* Sidebar width */ - right: 0; - position: fixed; /* Make sure the sidebar stays on the right */ - top: 0; - bottom: 0; - background-color: #fff; /* White background */ - overflow-y: auto; /* Allow scrolling if content overflows */ + width: 20em; + right: 0; } /* The navigation menu links */ @@ -176,25 +139,19 @@

INDRA Statements with Evidences

} .side-info h4 { - font-size: 10pt; + font-size: 14pt; display: block; text-decoration: none; - margin-bottom: 0; } - #sources-explanation { - font-size: 10pt; + .side-info-block { + padding: 1em 8px 1em 16px; } .source-desc { border-radius: 4px; - padding: 0em 0em; - font-size: 0.6em; - margin: 1px; - } - - h3.bg-white { - font-size: 13pt; + padding: 0.25em 0.5em 0.25em 0.5em; + margin: 4px; } @@ -1138,7 +1095,7 @@

-
+
@@ -1152,8 +1109,8 @@

+ onclick="toggler('ccd75923-6013-4d74-9b23-0fe68f2c185e');" + id="ccd75923-6013-4d74-9b23-0fe68f2c185e_heading">
CTNNB1 binds LEF1.
@@ -1275,7 +1232,7 @@
CTNNB1 binds

-
+
@@ -1287,8 +1244,8 @@
CTNNB1 binds
+ onclick="toggler( 'ccd75923-6013-4d74-9b23-0fe68f2c185e--3956928808920876' )" + id="ccd75923-6013-4d74-9b23-0fe68f2c185e--3956928808920876_heading">
LEF1 binds CTNNB1. @@ -1418,7 +1375,7 @@
+ id="ccd75923-6013-4d74-9b23-0fe68f2c185e--3956928808920876_group">
@@ -39999,8 +39956,8 @@
+ onclick="toggler( 'ccd75923-6013-4d74-9b23-0fe68f2c185e-29618800379845708' )" + id="ccd75923-6013-4d74-9b23-0fe68f2c185e-29618800379845708_heading">
CTNNB1 binds LEF1 and PITX2. @@ -40100,7 +40057,7 @@
+ id="ccd75923-6013-4d74-9b23-0fe68f2c185e-29618800379845708_group">
@@ -40984,8 +40941,8 @@
+ onclick="toggler( 'ccd75923-6013-4d74-9b23-0fe68f2c185e-6957036990254327' )" + id="ccd75923-6013-4d74-9b23-0fe68f2c185e-6957036990254327_heading">
TCF4 binds LEF1 and CTNNB1. @@ -41085,7 +41042,7 @@
+ id="ccd75923-6013-4d74-9b23-0fe68f2c185e-6957036990254327_group">
@@ -41845,8 +41802,8 @@
+ onclick="toggler( 'ccd75923-6013-4d74-9b23-0fe68f2c185e-2264178095591350' )" + id="ccd75923-6013-4d74-9b23-0fe68f2c185e-2264178095591350_heading">
Wnt binds CTNNB1 and LEF1. @@ -41946,7 +41903,7 @@
+ id="ccd75923-6013-4d74-9b23-0fe68f2c185e-2264178095591350_group">
@@ -42707,8 +42664,8 @@
+ onclick="toggler( 'ccd75923-6013-4d74-9b23-0fe68f2c185e-2692654667567618' )" + id="ccd75923-6013-4d74-9b23-0fe68f2c185e-2692654667567618_heading">
CTNNB1 binds LEF1 and TCF_LEF. @@ -42808,7 +42765,7 @@
+ id="ccd75923-6013-4d74-9b23-0fe68f2c185e-2692654667567618_group">
@@ -43382,8 +43339,8 @@
+ onclick="toggler( 'ccd75923-6013-4d74-9b23-0fe68f2c185e-13988771661306103' )" + id="ccd75923-6013-4d74-9b23-0fe68f2c185e-13988771661306103_heading">
LEF1 binds CTNNB1 and FHL2. @@ -43483,7 +43440,7 @@
+ id="ccd75923-6013-4d74-9b23-0fe68f2c185e-13988771661306103_group">
@@ -44057,8 +44014,8 @@
+ onclick="toggler( 'ccd75923-6013-4d74-9b23-0fe68f2c185e--17608802640300192' )" + id="ccd75923-6013-4d74-9b23-0fe68f2c185e--17608802640300192_heading">
LEF1 binds HNF1A and CTNNB1. @@ -44158,7 +44115,7 @@
+ id="ccd75923-6013-4d74-9b23-0fe68f2c185e--17608802640300192_group">
@@ -44608,8 +44565,8 @@
+ onclick="toggler( 'ccd75923-6013-4d74-9b23-0fe68f2c185e--19126068635528570' )" + id="ccd75923-6013-4d74-9b23-0fe68f2c185e--19126068635528570_heading">
WNT3A binds CTNNB1 and LEF1. @@ -44709,7 +44666,7 @@
+ id="ccd75923-6013-4d74-9b23-0fe68f2c185e--19126068635528570_group">
@@ -45035,8 +44992,8 @@
+ onclick="toggler( 'ccd75923-6013-4d74-9b23-0fe68f2c185e--11822116816072987' )" + id="ccd75923-6013-4d74-9b23-0fe68f2c185e--11822116816072987_heading">
CTNNB1 binds SIRT1 and LEF1. @@ -45136,7 +45093,7 @@
+ id="ccd75923-6013-4d74-9b23-0fe68f2c185e--11822116816072987_group">
@@ -45400,8 +45357,8 @@
+ onclick="toggler( 'ccd75923-6013-4d74-9b23-0fe68f2c185e-24669673375422319' )" + id="ccd75923-6013-4d74-9b23-0fe68f2c185e-24669673375422319_heading">
KLF10 binds LEF1 and CTNNB1. @@ -45501,7 +45458,7 @@
+ id="ccd75923-6013-4d74-9b23-0fe68f2c185e-24669673375422319_group">
@@ -45703,8 +45660,8 @@
+ onclick="toggler( 'ccd75923-6013-4d74-9b23-0fe68f2c185e--31992473524411751' )" + id="ccd75923-6013-4d74-9b23-0fe68f2c185e--31992473524411751_heading">
LEF1 binds CTNNB1 and NCAPD2. @@ -45804,7 +45761,7 @@
+ id="ccd75923-6013-4d74-9b23-0fe68f2c185e--31992473524411751_group">
@@ -46006,8 +45963,8 @@
+ onclick="toggler( 'ccd75923-6013-4d74-9b23-0fe68f2c185e-27756433940953801' )" + id="ccd75923-6013-4d74-9b23-0fe68f2c185e-27756433940953801_heading">
CTNNB1 binds TCF7L2 and LEF1. @@ -46107,7 +46064,7 @@
+ id="ccd75923-6013-4d74-9b23-0fe68f2c185e-27756433940953801_group">
@@ -46247,8 +46204,8 @@
+ onclick="toggler( 'ccd75923-6013-4d74-9b23-0fe68f2c185e-27318541668906003' )" + id="ccd75923-6013-4d74-9b23-0fe68f2c185e-27318541668906003_heading">
CTNNB1 binds LEF1 and GSK3B. @@ -46348,7 +46305,7 @@
+ id="ccd75923-6013-4d74-9b23-0fe68f2c185e-27318541668906003_group">
@@ -46488,8 +46445,8 @@
+ onclick="toggler( 'ccd75923-6013-4d74-9b23-0fe68f2c185e-22316626476000593' )" + id="ccd75923-6013-4d74-9b23-0fe68f2c185e-22316626476000593_heading">
RUNX2 binds CTNNB1 and LEF1. @@ -46589,7 +46546,7 @@
+ id="ccd75923-6013-4d74-9b23-0fe68f2c185e-22316626476000593_group">
@@ -46729,8 +46686,8 @@
+ onclick="toggler( 'ccd75923-6013-4d74-9b23-0fe68f2c185e--9589549602574229' )" + id="ccd75923-6013-4d74-9b23-0fe68f2c185e--9589549602574229_heading">
CTNNB1 binds TCF7 and LEF1. @@ -46830,7 +46787,7 @@
+ id="ccd75923-6013-4d74-9b23-0fe68f2c185e--9589549602574229_group">
@@ -46970,8 +46927,8 @@
+ onclick="toggler( 'ccd75923-6013-4d74-9b23-0fe68f2c185e--34330103323056865' )" + id="ccd75923-6013-4d74-9b23-0fe68f2c185e--34330103323056865_heading">
MTDH binds LEF1 and CTNNB1. @@ -47071,7 +47028,7 @@
+ id="ccd75923-6013-4d74-9b23-0fe68f2c185e--34330103323056865_group">
@@ -47210,8 +47167,8 @@
+ onclick="toggler( 'ccd75923-6013-4d74-9b23-0fe68f2c185e--32591290229375559' )" + id="ccd75923-6013-4d74-9b23-0fe68f2c185e--32591290229375559_heading">
LEF1 binds CTNNB1 and TLE1. @@ -47311,7 +47268,7 @@
+ id="ccd75923-6013-4d74-9b23-0fe68f2c185e--32591290229375559_group">
@@ -47451,8 +47408,8 @@
+ onclick="toggler( 'ccd75923-6013-4d74-9b23-0fe68f2c185e--31348629510864397' )" + id="ccd75923-6013-4d74-9b23-0fe68f2c185e--31348629510864397_heading">
LEF1 binds TCF3 and CTNNB1. @@ -47552,7 +47509,7 @@
+ id="ccd75923-6013-4d74-9b23-0fe68f2c185e--31348629510864397_group">
@@ -47692,8 +47649,8 @@
+ onclick="toggler( 'ccd75923-6013-4d74-9b23-0fe68f2c185e--23739666623344803' )" + id="ccd75923-6013-4d74-9b23-0fe68f2c185e--23739666623344803_heading">
CTNNB1 binds LEF1 and MITF. @@ -47793,7 +47750,7 @@
+ id="ccd75923-6013-4d74-9b23-0fe68f2c185e--23739666623344803_group">
@@ -47933,8 +47890,8 @@
+ onclick="toggler( 'ccd75923-6013-4d74-9b23-0fe68f2c185e--19243497291280737' )" + id="ccd75923-6013-4d74-9b23-0fe68f2c185e--19243497291280737_heading">
SMAD4 binds CTNNB1 and LEF1. @@ -48034,7 +47991,7 @@
+ id="ccd75923-6013-4d74-9b23-0fe68f2c185e--19243497291280737_group">
@@ -48174,8 +48131,8 @@
+ onclick="toggler( 'ccd75923-6013-4d74-9b23-0fe68f2c185e--14661076775394056' )" + id="ccd75923-6013-4d74-9b23-0fe68f2c185e--14661076775394056_heading">
VDR binds LEF1 and CTNNB1. @@ -48275,7 +48232,7 @@
+ id="ccd75923-6013-4d74-9b23-0fe68f2c185e--14661076775394056_group">
@@ -48415,8 +48372,8 @@
+ onclick="toggler( 'ccd75923-6013-4d74-9b23-0fe68f2c185e-16584705468148029' )" + id="ccd75923-6013-4d74-9b23-0fe68f2c185e-16584705468148029_heading">
Phosphorylated LEF1 binds CTNNB1. @@ -48516,7 +48473,7 @@
+ id="ccd75923-6013-4d74-9b23-0fe68f2c185e-16584705468148029_group">
@@ -48594,8 +48551,8 @@
+ onclick="toggler( 'ccd75923-6013-4d74-9b23-0fe68f2c185e-9526097030816088' )" + id="ccd75923-6013-4d74-9b23-0fe68f2c185e-9526097030816088_heading">
LEF1 binds GST and CTNNB1. @@ -48695,7 +48652,7 @@
+ id="ccd75923-6013-4d74-9b23-0fe68f2c185e-9526097030816088_group">
@@ -48773,8 +48730,8 @@
+ onclick="toggler( 'ccd75923-6013-4d74-9b23-0fe68f2c185e-480162846331168' )" + id="ccd75923-6013-4d74-9b23-0fe68f2c185e-480162846331168_heading">
LEF1 binds LGALS12 and CTNNB1. @@ -48874,7 +48831,7 @@
+ id="ccd75923-6013-4d74-9b23-0fe68f2c185e-480162846331168_group">
@@ -48952,8 +48909,8 @@
+ onclick="toggler( 'ccd75923-6013-4d74-9b23-0fe68f2c185e-4496376453965882' )" + id="ccd75923-6013-4d74-9b23-0fe68f2c185e-4496376453965882_heading">
TGFB3 binds LEF1 and CTNNB1. @@ -49053,7 +49010,7 @@
+ id="ccd75923-6013-4d74-9b23-0fe68f2c185e-4496376453965882_group">
@@ -49131,8 +49088,8 @@
+ onclick="toggler( 'ccd75923-6013-4d74-9b23-0fe68f2c185e-3396709214872261' )" + id="ccd75923-6013-4d74-9b23-0fe68f2c185e-3396709214872261_heading">
CTNNB1 binds LEF1 and NR4A2. @@ -49232,7 +49189,7 @@
+ id="ccd75923-6013-4d74-9b23-0fe68f2c185e-3396709214872261_group">
@@ -49310,8 +49267,8 @@
+ onclick="toggler( 'ccd75923-6013-4d74-9b23-0fe68f2c185e-31768936644658663' )" + id="ccd75923-6013-4d74-9b23-0fe68f2c185e-31768936644658663_heading">
CTNNB1 binds LEF1 and GAPDH. @@ -49411,7 +49368,7 @@
+ id="ccd75923-6013-4d74-9b23-0fe68f2c185e-31768936644658663_group">
@@ -49489,8 +49446,8 @@
+ onclick="toggler( 'ccd75923-6013-4d74-9b23-0fe68f2c185e-28646030935457285' )" + id="ccd75923-6013-4d74-9b23-0fe68f2c185e-28646030935457285_heading">
LEF1 binds CTNNB1 and Cohesin. @@ -49590,7 +49547,7 @@
+ id="ccd75923-6013-4d74-9b23-0fe68f2c185e-28646030935457285_group">
@@ -49668,8 +49625,8 @@
+ onclick="toggler( 'ccd75923-6013-4d74-9b23-0fe68f2c185e-25838858521969308' )" + id="ccd75923-6013-4d74-9b23-0fe68f2c185e-25838858521969308_heading">
PSTPIP1 binds CTNNB1 and LEF1. @@ -49769,7 +49726,7 @@
+ id="ccd75923-6013-4d74-9b23-0fe68f2c185e-25838858521969308_group">
@@ -49847,8 +49804,8 @@
+ onclick="toggler( 'ccd75923-6013-4d74-9b23-0fe68f2c185e-21982697371175926' )" + id="ccd75923-6013-4d74-9b23-0fe68f2c185e-21982697371175926_heading">
CTNNB1 binds LEF1 and EP300. @@ -49948,7 +49905,7 @@
+ id="ccd75923-6013-4d74-9b23-0fe68f2c185e-21982697371175926_group">
@@ -50026,8 +49983,8 @@
+ onclick="toggler( 'ccd75923-6013-4d74-9b23-0fe68f2c185e-21298447956750950' )" + id="ccd75923-6013-4d74-9b23-0fe68f2c185e-21298447956750950_heading">
LEF1 binds HNF4A and CTNNB1. @@ -50127,7 +50084,7 @@
+ id="ccd75923-6013-4d74-9b23-0fe68f2c185e-21298447956750950_group">
@@ -50205,8 +50162,8 @@
+ onclick="toggler( 'ccd75923-6013-4d74-9b23-0fe68f2c185e-19737899353137844' )" + id="ccd75923-6013-4d74-9b23-0fe68f2c185e-19737899353137844_heading">
CTNNB1 binds SMAD2_3 and LEF1. @@ -50306,7 +50263,7 @@
+ id="ccd75923-6013-4d74-9b23-0fe68f2c185e-19737899353137844_group">
@@ -50384,8 +50341,8 @@
+ onclick="toggler( 'ccd75923-6013-4d74-9b23-0fe68f2c185e-16751790197568473' )" + id="ccd75923-6013-4d74-9b23-0fe68f2c185e-16751790197568473_heading">
CD274 binds CTNNB1 and LEF1. @@ -50485,7 +50442,7 @@
+ id="ccd75923-6013-4d74-9b23-0fe68f2c185e-16751790197568473_group">
@@ -50563,8 +50520,8 @@
+ onclick="toggler( 'ccd75923-6013-4d74-9b23-0fe68f2c185e-16737116795661387' )" + id="ccd75923-6013-4d74-9b23-0fe68f2c185e-16737116795661387_heading">
TNFRSF10B binds LEF1 and CTNNB1. @@ -50664,7 +50621,7 @@
+ id="ccd75923-6013-4d74-9b23-0fe68f2c185e-16737116795661387_group">
@@ -50742,8 +50699,8 @@
+ onclick="toggler( 'ccd75923-6013-4d74-9b23-0fe68f2c185e-15792438666115609' )" + id="ccd75923-6013-4d74-9b23-0fe68f2c185e-15792438666115609_heading">
LEF1 binds CTNNB1 and AXIN. @@ -50843,7 +50800,7 @@
+ id="ccd75923-6013-4d74-9b23-0fe68f2c185e-15792438666115609_group">
@@ -50921,8 +50878,8 @@
+ onclick="toggler( 'ccd75923-6013-4d74-9b23-0fe68f2c185e-15252857050938813' )" + id="ccd75923-6013-4d74-9b23-0fe68f2c185e-15252857050938813_heading">
CTNNB1 binds LEF1 and CDH1. @@ -51022,7 +50979,7 @@
+ id="ccd75923-6013-4d74-9b23-0fe68f2c185e-15252857050938813_group">
@@ -51101,8 +51058,8 @@
+ onclick="toggler( 'ccd75923-6013-4d74-9b23-0fe68f2c185e-11961579137538770' )" + id="ccd75923-6013-4d74-9b23-0fe68f2c185e-11961579137538770_heading">
APC binds CTNNB1 and LEF1. @@ -51202,7 +51159,7 @@
+ id="ccd75923-6013-4d74-9b23-0fe68f2c185e-11961579137538770_group">
@@ -51280,8 +51237,8 @@
+ onclick="toggler( 'ccd75923-6013-4d74-9b23-0fe68f2c185e-11484432151305999' )" + id="ccd75923-6013-4d74-9b23-0fe68f2c185e-11484432151305999_heading">
CXCL1 binds CTNNB1 and LEF1. @@ -51381,7 +51338,7 @@
+ id="ccd75923-6013-4d74-9b23-0fe68f2c185e-11484432151305999_group">
@@ -51459,8 +51416,8 @@
+ onclick="toggler( 'ccd75923-6013-4d74-9b23-0fe68f2c185e-10029578924294300' )" + id="ccd75923-6013-4d74-9b23-0fe68f2c185e-10029578924294300_heading">
CTNNB1 binds PRMT6 and LEF1. @@ -51560,7 +51517,7 @@
+ id="ccd75923-6013-4d74-9b23-0fe68f2c185e-10029578924294300_group">
@@ -51638,8 +51595,8 @@
+ onclick="toggler( 'ccd75923-6013-4d74-9b23-0fe68f2c185e--9484087371380806' )" + id="ccd75923-6013-4d74-9b23-0fe68f2c185e--9484087371380806_heading">
Tcf7l1-a binds LEF1 and CTNNB1. @@ -51739,7 +51696,7 @@
+ id="ccd75923-6013-4d74-9b23-0fe68f2c185e--9484087371380806_group">
@@ -51817,8 +51774,8 @@
+ onclick="toggler( 'ccd75923-6013-4d74-9b23-0fe68f2c185e--9053086901454015' )" + id="ccd75923-6013-4d74-9b23-0fe68f2c185e--9053086901454015_heading">
CTNNB1 binds LEF1 and RAC1. @@ -51918,7 +51875,7 @@
+ id="ccd75923-6013-4d74-9b23-0fe68f2c185e--9053086901454015_group">
@@ -51996,8 +51953,8 @@
+ onclick="toggler( 'ccd75923-6013-4d74-9b23-0fe68f2c185e--604299704594394' )" + id="ccd75923-6013-4d74-9b23-0fe68f2c185e--604299704594394_heading">
EPCAM binds CTNNB1 and LEF1. @@ -52097,7 +52054,7 @@
+ id="ccd75923-6013-4d74-9b23-0fe68f2c185e--604299704594394_group">
@@ -52175,8 +52132,8 @@
+ onclick="toggler( 'ccd75923-6013-4d74-9b23-0fe68f2c185e--4096361839257048' )" + id="ccd75923-6013-4d74-9b23-0fe68f2c185e--4096361839257048_heading">
CTNNB1 binds AR and LEF1. @@ -52276,7 +52233,7 @@
+ id="ccd75923-6013-4d74-9b23-0fe68f2c185e--4096361839257048_group">
@@ -52354,8 +52311,8 @@
+ onclick="toggler( 'ccd75923-6013-4d74-9b23-0fe68f2c185e--32402969844342653' )" + id="ccd75923-6013-4d74-9b23-0fe68f2c185e--32402969844342653_heading">
CTNNB1 binds LEF1 and SMAD7. @@ -52455,7 +52412,7 @@
+ id="ccd75923-6013-4d74-9b23-0fe68f2c185e--32402969844342653_group">
@@ -52533,8 +52490,8 @@
+ onclick="toggler( 'ccd75923-6013-4d74-9b23-0fe68f2c185e--29823017347952231' )" + id="ccd75923-6013-4d74-9b23-0fe68f2c185e--29823017347952231_heading">
LEF1 binds CTNNB1 and JUP. @@ -52634,7 +52591,7 @@
+ id="ccd75923-6013-4d74-9b23-0fe68f2c185e--29823017347952231_group">
@@ -52712,8 +52669,8 @@
+ onclick="toggler( 'ccd75923-6013-4d74-9b23-0fe68f2c185e--24635667139960288' )" + id="ccd75923-6013-4d74-9b23-0fe68f2c185e--24635667139960288_heading">
LEF1 binds CTNNB1 and LHX3. @@ -52813,7 +52770,7 @@
+ id="ccd75923-6013-4d74-9b23-0fe68f2c185e--24635667139960288_group">
@@ -52891,8 +52848,8 @@
+ onclick="toggler( 'ccd75923-6013-4d74-9b23-0fe68f2c185e--1945394382643553' )" + id="ccd75923-6013-4d74-9b23-0fe68f2c185e--1945394382643553_heading">
DLL1 binds CTNNB1 and LEF1. @@ -52992,7 +52949,7 @@
+ id="ccd75923-6013-4d74-9b23-0fe68f2c185e--1945394382643553_group">
@@ -53070,8 +53027,8 @@
+ onclick="toggler( 'ccd75923-6013-4d74-9b23-0fe68f2c185e--1799841953764187' )" + id="ccd75923-6013-4d74-9b23-0fe68f2c185e--1799841953764187_heading">
HINT1 binds CTNNB1 and LEF1. @@ -53171,7 +53128,7 @@
+ id="ccd75923-6013-4d74-9b23-0fe68f2c185e--1799841953764187_group">
@@ -53249,8 +53206,8 @@
+ onclick="toggler( 'ccd75923-6013-4d74-9b23-0fe68f2c185e--16614276956979940' )" + id="ccd75923-6013-4d74-9b23-0fe68f2c185e--16614276956979940_heading">
CTNNB1 binds DKK2 and LEF1. @@ -53350,7 +53307,7 @@
+ id="ccd75923-6013-4d74-9b23-0fe68f2c185e--16614276956979940_group">
@@ -53438,8 +53395,8 @@
+ onclick="toggler('638e99fc-6819-4fee-869d-2d328b4ef04b');" + id="638e99fc-6819-4fee-869d-2d328b4ef04b_heading">
CTNNB1 activates LEF1.
@@ -53546,7 +53503,7 @@
CTNNB1 activ
-
+
@@ -53558,8 +53515,8 @@
CTNNB1 activ
+ onclick="toggler( '638e99fc-6819-4fee-869d-2d328b4ef04b-3476285540477525' )" + id="638e99fc-6819-4fee-869d-2d328b4ef04b-3476285540477525_heading">
CTNNB1 activates LEF1. @@ -53669,7 +53626,7 @@
+ id="638e99fc-6819-4fee-869d-2d328b4ef04b-3476285540477525_group">
@@ -59947,8 +59904,8 @@
+ onclick="toggler( '638e99fc-6819-4fee-869d-2d328b4ef04b--33869334428894787' )" + id="638e99fc-6819-4fee-869d-2d328b4ef04b--33869334428894787_heading">
Transcriptionally active CTNNB1 activates LEF1. @@ -60048,7 +60005,7 @@
+ id="638e99fc-6819-4fee-869d-2d328b4ef04b--33869334428894787_group">
@@ -60188,8 +60145,8 @@
+ onclick="toggler( '638e99fc-6819-4fee-869d-2d328b4ef04b--28168670139526755' )" + id="638e99fc-6819-4fee-869d-2d328b4ef04b--28168670139526755_heading">
CTNNB1 bound to LEF1 activates LEF1. @@ -60289,7 +60246,7 @@
+ id="638e99fc-6819-4fee-869d-2d328b4ef04b--28168670139526755_group">
@@ -60429,8 +60386,8 @@
+ onclick="toggler( '638e99fc-6819-4fee-869d-2d328b4ef04b-3502824333174167' )" + id="638e99fc-6819-4fee-869d-2d328b4ef04b-3502824333174167_heading">
CTNNB1-S37A activates LEF1. @@ -60530,7 +60487,7 @@
+ id="638e99fc-6819-4fee-869d-2d328b4ef04b-3502824333174167_group">
@@ -60608,8 +60565,8 @@
+ onclick="toggler( '638e99fc-6819-4fee-869d-2d328b4ef04b-18481722808515866' )" + id="638e99fc-6819-4fee-869d-2d328b4ef04b-18481722808515866_heading">
CTNNB1 bound to PITX2 activates LEF1. @@ -60709,7 +60666,7 @@
+ id="638e99fc-6819-4fee-869d-2d328b4ef04b-18481722808515866_group">
@@ -60787,8 +60744,8 @@
+ onclick="toggler( '638e99fc-6819-4fee-869d-2d328b4ef04b-14257305887366432' )" + id="638e99fc-6819-4fee-869d-2d328b4ef04b-14257305887366432_heading">
CTNNB1 bound to TCF4 activates LEF1. @@ -60888,7 +60845,7 @@
+ id="638e99fc-6819-4fee-869d-2d328b4ef04b-14257305887366432_group">
@@ -60966,8 +60923,8 @@
+ onclick="toggler( '638e99fc-6819-4fee-869d-2d328b4ef04b--1646881445262652' )" + id="638e99fc-6819-4fee-869d-2d328b4ef04b--1646881445262652_heading">
CTNNB1 bound to its activates LEF1. @@ -61067,7 +61024,7 @@
+ id="638e99fc-6819-4fee-869d-2d328b4ef04b--1646881445262652_group">
@@ -61155,8 +61112,8 @@
+ onclick="toggler('16d86cd9-9758-44bb-aad1-bbd6a1019005');" + id="16d86cd9-9758-44bb-aad1-bbd6a1019005_heading">
CTNNB1 increases the amount of LEF1.
@@ -61253,7 +61210,7 @@
CTNNB1 incre
-
+
@@ -61265,8 +61222,8 @@
CTNNB1 incre
+ onclick="toggler( '16d86cd9-9758-44bb-aad1-bbd6a1019005-24073872996465754' )" + id="16d86cd9-9758-44bb-aad1-bbd6a1019005-24073872996465754_heading">
CTNNB1 increases the amount of LEF1. @@ -61371,7 +61328,7 @@
+ id="16d86cd9-9758-44bb-aad1-bbd6a1019005-24073872996465754_group">
@@ -62565,8 +62522,8 @@
+ onclick="toggler( '16d86cd9-9758-44bb-aad1-bbd6a1019005--18122722326450403' )" + id="16d86cd9-9758-44bb-aad1-bbd6a1019005--18122722326450403_heading">
Modified CTNNB1 increases the amount of LEF1. @@ -62666,7 +62623,7 @@
+ id="16d86cd9-9758-44bb-aad1-bbd6a1019005--18122722326450403_group">
@@ -62806,8 +62763,8 @@
+ onclick="toggler( '16d86cd9-9758-44bb-aad1-bbd6a1019005-24305422461670616' )" + id="16d86cd9-9758-44bb-aad1-bbd6a1019005-24305422461670616_heading">
CTNNB1 increases the amount of sumoylated LEF1. @@ -62907,7 +62864,7 @@
+ id="16d86cd9-9758-44bb-aad1-bbd6a1019005-24305422461670616_group">
@@ -62985,8 +62942,8 @@
+ onclick="toggler( '16d86cd9-9758-44bb-aad1-bbd6a1019005-10214529737267247' )" + id="16d86cd9-9758-44bb-aad1-bbd6a1019005-10214529737267247_heading">
CTNNB1 bound to LEF1 increases the amount of LEF1. @@ -63086,7 +63043,7 @@
+ id="16d86cd9-9758-44bb-aad1-bbd6a1019005-10214529737267247_group">
@@ -63164,8 +63121,8 @@
+ onclick="toggler( '16d86cd9-9758-44bb-aad1-bbd6a1019005--20562209741866189' )" + id="16d86cd9-9758-44bb-aad1-bbd6a1019005--20562209741866189_heading">
CTNNB1 bound to PITX2 increases the amount of LEF1. @@ -63265,7 +63222,7 @@
+ id="16d86cd9-9758-44bb-aad1-bbd6a1019005--20562209741866189_group">
@@ -63353,8 +63310,8 @@
+ onclick="toggler('5189de05-e0b2-464f-aac9-0517d2857c61');" + id="5189de05-e0b2-464f-aac9-0517d2857c61_heading">
CTNNB1 inhibits LEF1.
@@ -63456,7 +63413,7 @@
CTNNB1 inhib
-
+
@@ -63468,8 +63425,8 @@
CTNNB1 inhib
+ onclick="toggler( '5189de05-e0b2-464f-aac9-0517d2857c61--28871778998254830' )" + id="5189de05-e0b2-464f-aac9-0517d2857c61--28871778998254830_heading">
CTNNB1 inhibits LEF1. @@ -63579,7 +63536,7 @@
+ id="5189de05-e0b2-464f-aac9-0517d2857c61--28871778998254830_group">
@@ -64339,8 +64296,8 @@
+ onclick="toggler( '5189de05-e0b2-464f-aac9-0517d2857c61-33550122620305779' )" + id="5189de05-e0b2-464f-aac9-0517d2857c61-33550122620305779_heading">
CTNNB1 bound to TOB1 inhibits LEF1. @@ -64440,7 +64397,7 @@
+ id="5189de05-e0b2-464f-aac9-0517d2857c61-33550122620305779_group">
@@ -64518,8 +64475,8 @@
+ onclick="toggler( '5189de05-e0b2-464f-aac9-0517d2857c61--30764479391051259' )" + id="5189de05-e0b2-464f-aac9-0517d2857c61--30764479391051259_heading">
CTNNB1 bound to LEF1 inhibits LEF1. @@ -64619,7 +64576,7 @@
+ id="5189de05-e0b2-464f-aac9-0517d2857c61--30764479391051259_group">
@@ -64707,8 +64664,8 @@
+ onclick="toggler('1018eb85-bd4d-4f9c-99da-af77f2ef8a9f');" + id="1018eb85-bd4d-4f9c-99da-af77f2ef8a9f_heading">
CTNNB1 decreases the amount of LEF1.
@@ -64800,7 +64757,7 @@
CTNNB1 decre
-
+
@@ -64812,8 +64769,8 @@
CTNNB1 decre
+ onclick="toggler( '1018eb85-bd4d-4f9c-99da-af77f2ef8a9f-35939315667740067' )" + id="1018eb85-bd4d-4f9c-99da-af77f2ef8a9f-35939315667740067_heading">
CTNNB1 decreases the amount of LEF1. @@ -64913,7 +64870,7 @@
+ id="1018eb85-bd4d-4f9c-99da-af77f2ef8a9f-35939315667740067_group">
@@ -65239,8 +65196,8 @@
+ onclick="toggler( '1018eb85-bd4d-4f9c-99da-af77f2ef8a9f--28812488204681615' )" + id="1018eb85-bd4d-4f9c-99da-af77f2ef8a9f--28812488204681615_heading">
Modified CTNNB1 decreases the amount of LEF1. @@ -65340,7 +65297,7 @@
+ id="1018eb85-bd4d-4f9c-99da-af77f2ef8a9f--28812488204681615_group">
@@ -65428,8 +65385,8 @@
+ onclick="toggler('f5a6d6d9-53a0-4c64-a383-5aefac641542');" + id="f5a6d6d9-53a0-4c64-a383-5aefac641542_heading">
CTNNB1 acetylates LEF1.
@@ -65521,7 +65478,7 @@
CTNNB1 acety
-
+
@@ -65533,8 +65490,8 @@
CTNNB1 acety
+ onclick="toggler( 'f5a6d6d9-53a0-4c64-a383-5aefac641542-18687563873101264' )" + id="f5a6d6d9-53a0-4c64-a383-5aefac641542-18687563873101264_heading">
CTNNB1 leads to the acetylation of LEF1. @@ -65634,7 +65591,7 @@
+ id="f5a6d6d9-53a0-4c64-a383-5aefac641542-18687563873101264_group">
@@ -65794,56 +65751,14 @@
padding-right: 1em; } - /* The footer */ - .footer { - position: fixed; /* Make sure the footer is always visible at the bottom */ - bottom: 0; /* Stick it to the bottom of the page */ - left: 0; - right: 20em; - color: #606060; - text-align: left; - padding: 0.5em; - box-shadow: 0 -2px 10px rgba(0, 0, 0, 0.1); - height: 65; - } - - .footer h4, .footer p, .footer a { - font-size: 9pt; - line-height: 1.3; - margin: 0; /* Reduces vertical spacing */ - } - - .side-info-block { - padding: 0em 8px 0em 8px; - margin-bottom: 0; - } - - /* Footer links */ - .il-nav-link { - display: block; - margin: 5px 0; - color: #256DC5; /* Blue color */ - text-decoration: none; - } - - .il-nav-link:hover { - text-decoration: underline; - color: #007bff; - } - - #about-this-project p, #about-this-project a { - font-size: 9pt; - margin-bottom: 0; + .left { + width: 20em; + left: 0; } .right { - width: 20em; /* Sidebar width */ - right: 0; - position: fixed; /* Make sure the sidebar stays on the right */ - top: 0; - bottom: 0; - background-color: #fff; /* White background */ - overflow-y: auto; /* Allow scrolling if content overflows */ + width: 20em; + right: 0; } /* The navigation menu links */ @@ -65854,25 +65769,19 @@
} .side-info h4 { - font-size: 10pt; + font-size: 14pt; display: block; text-decoration: none; - margin-bottom: 0; } - #sources-explanation { - font-size: 10pt; + .side-info-block { + padding: 1em 8px 1em 16px; } .source-desc { border-radius: 4px; - padding: 0em 0em; - font-size: 0.6em; - margin: 1px; - } - - h3.bg-white { - font-size: 13pt; + padding: 0.25em 0.5em 0.25em 0.5em; + margin: 4px; } @@ -66816,7 +66725,7 @@

-
+
@@ -66829,7 +66738,7 @@

-
+
@@ -66841,8 +66750,8 @@

+ onclick="toggler( '7e9bd1b9-c989-4e2f-96bf-3a649687dda3-16789706344284407' )" + id="7e9bd1b9-c989-4e2f-96bf-3a649687dda3-16789706344284407_heading">
CTNNB1 decreases the amount of FABP4. @@ -66942,7 +66851,7 @@
+ id="7e9bd1b9-c989-4e2f-96bf-3a649687dda3-16789706344284407_group">
@@ -67102,56 +67011,14 @@
padding-right: 1em; } - /* The footer */ - .footer { - position: fixed; /* Make sure the footer is always visible at the bottom */ - bottom: 0; /* Stick it to the bottom of the page */ - left: 0; - right: 20em; - color: #606060; - text-align: left; - padding: 0.5em; - box-shadow: 0 -2px 10px rgba(0, 0, 0, 0.1); - height: 65; - } - - .footer h4, .footer p, .footer a { - font-size: 9pt; - line-height: 1.3; - margin: 0; /* Reduces vertical spacing */ - } - - .side-info-block { - padding: 0em 8px 0em 8px; - margin-bottom: 0; - } - - /* Footer links */ - .il-nav-link { - display: block; - margin: 5px 0; - color: #256DC5; /* Blue color */ - text-decoration: none; - } - - .il-nav-link:hover { - text-decoration: underline; - color: #007bff; - } - - #about-this-project p, #about-this-project a { - font-size: 9pt; - margin-bottom: 0; + .left { + width: 20em; + left: 0; } .right { - width: 20em; /* Sidebar width */ - right: 0; - position: fixed; /* Make sure the sidebar stays on the right */ - top: 0; - bottom: 0; - background-color: #fff; /* White background */ - overflow-y: auto; /* Allow scrolling if content overflows */ + width: 20em; + right: 0; } /* The navigation menu links */ @@ -67162,25 +67029,19 @@
} .side-info h4 { - font-size: 10pt; + font-size: 14pt; display: block; text-decoration: none; - margin-bottom: 0; } - #sources-explanation { - font-size: 10pt; + .side-info-block { + padding: 1em 8px 1em 16px; } .source-desc { border-radius: 4px; - padding: 0em 0em; - font-size: 0.6em; - margin: 1px; - } - - h3.bg-white { - font-size: 13pt; + padding: 0.25em 0.5em 0.25em 0.5em; + margin: 4px; } @@ -68124,7 +67985,7 @@

-
+
@@ -68138,8 +67999,8 @@

+ onclick="toggler('17f94d89-00b6-418b-b48c-f56033de75fe');" + id="17f94d89-00b6-418b-b48c-f56033de75fe_heading">
CTNNB1 activates DKK4.
@@ -68231,7 +68092,7 @@
CTNNB1 activ

-
+
@@ -68243,8 +68104,8 @@
CTNNB1 activ
+ onclick="toggler( '17f94d89-00b6-418b-b48c-f56033de75fe-33728523169869412' )" + id="17f94d89-00b6-418b-b48c-f56033de75fe-33728523169869412_heading">
CTNNB1 activates DKK4. @@ -68344,7 +68205,7 @@
+ id="17f94d89-00b6-418b-b48c-f56033de75fe-33728523169869412_group">
@@ -68804,8 +68665,8 @@
+ onclick="toggler('205158c6-7228-4f5d-ad0b-9fc5725c849e');" + id="205158c6-7228-4f5d-ad0b-9fc5725c849e_heading">
CTNNB1 binds DKK4.
@@ -68902,7 +68763,7 @@
CTNNB1 binds
-
+
@@ -68914,8 +68775,8 @@
CTNNB1 binds
+ onclick="toggler( '205158c6-7228-4f5d-ad0b-9fc5725c849e-33347782181673413' )" + id="205158c6-7228-4f5d-ad0b-9fc5725c849e-33347782181673413_heading">
DKK4 binds CTNNB1. @@ -69020,7 +68881,7 @@
+ id="205158c6-7228-4f5d-ad0b-9fc5725c849e-33347782181673413_group">
@@ -69294,8 +69155,8 @@
+ onclick="toggler('7c327cb7-e724-4b7a-9ce8-4a0c43f4b0af');" + id="7c327cb7-e724-4b7a-9ce8-4a0c43f4b0af_heading">
CTNNB1 increases the amount of DKK4.
@@ -69392,7 +69253,7 @@
CTNNB1 incre
-
+
@@ -69404,8 +69265,8 @@
CTNNB1 incre
+ onclick="toggler( '7c327cb7-e724-4b7a-9ce8-4a0c43f4b0af--32358899428670312' )" + id="7c327cb7-e724-4b7a-9ce8-4a0c43f4b0af--32358899428670312_heading">
CTNNB1 increases the amount of DKK4. @@ -69510,7 +69371,7 @@
+ id="7c327cb7-e724-4b7a-9ce8-4a0c43f4b0af--32358899428670312_group">
@@ -69660,8 +69521,8 @@
+ onclick="toggler('9d30d4fb-ba2a-462a-b02b-3fb8b34a4c58');" + id="9d30d4fb-ba2a-462a-b02b-3fb8b34a4c58_heading">
CTNNB1 decreases the amount of DKK4.
@@ -69748,7 +69609,7 @@
CTNNB1 decre
-
+
@@ -69760,8 +69621,8 @@
CTNNB1 decre
+ onclick="toggler( '9d30d4fb-ba2a-462a-b02b-3fb8b34a4c58-34747166071998815' )" + id="9d30d4fb-ba2a-462a-b02b-3fb8b34a4c58-34747166071998815_heading">
CTNNB1 decreases the amount of DKK4. @@ -69856,7 +69717,7 @@
+ id="9d30d4fb-ba2a-462a-b02b-3fb8b34a4c58-34747166071998815_group">
@@ -69954,56 +69815,14 @@
padding-right: 1em; } - /* The footer */ - .footer { - position: fixed; /* Make sure the footer is always visible at the bottom */ - bottom: 0; /* Stick it to the bottom of the page */ - left: 0; - right: 20em; - color: #606060; - text-align: left; - padding: 0.5em; - box-shadow: 0 -2px 10px rgba(0, 0, 0, 0.1); - height: 65; - } - - .footer h4, .footer p, .footer a { - font-size: 9pt; - line-height: 1.3; - margin: 0; /* Reduces vertical spacing */ - } - - .side-info-block { - padding: 0em 8px 0em 8px; - margin-bottom: 0; - } - - /* Footer links */ - .il-nav-link { - display: block; - margin: 5px 0; - color: #256DC5; /* Blue color */ - text-decoration: none; - } - - .il-nav-link:hover { - text-decoration: underline; - color: #007bff; - } - - #about-this-project p, #about-this-project a { - font-size: 9pt; - margin-bottom: 0; + .left { + width: 20em; + left: 0; } .right { - width: 20em; /* Sidebar width */ - right: 0; - position: fixed; /* Make sure the sidebar stays on the right */ - top: 0; - bottom: 0; - background-color: #fff; /* White background */ - overflow-y: auto; /* Allow scrolling if content overflows */ + width: 20em; + right: 0; } /* The navigation menu links */ @@ -70014,25 +69833,19 @@
} .side-info h4 { - font-size: 10pt; + font-size: 14pt; display: block; text-decoration: none; - margin-bottom: 0; } - #sources-explanation { - font-size: 10pt; + .side-info-block { + padding: 1em 8px 1em 16px; } .source-desc { border-radius: 4px; - padding: 0em 0em; - font-size: 0.6em; - margin: 1px; - } - - h3.bg-white { - font-size: 13pt; + padding: 0.25em 0.5em 0.25em 0.5em; + margin: 4px; } @@ -70976,7 +70789,7 @@

-
+
@@ -70990,8 +70803,8 @@

+ onclick="toggler('575369c8-6983-4915-895d-80aab9b659eb');" + id="575369c8-6983-4915-895d-80aab9b659eb_heading">
CTNNB1 binds NOTUM.
@@ -71083,7 +70896,7 @@
CTNNB1 binds

-
+
@@ -71095,8 +70908,8 @@
CTNNB1 binds
+ onclick="toggler( '575369c8-6983-4915-895d-80aab9b659eb--15050519431558438' )" + id="575369c8-6983-4915-895d-80aab9b659eb--15050519431558438_heading">
NOTUM binds CTNNB1. @@ -71196,7 +71009,7 @@
+ id="575369c8-6983-4915-895d-80aab9b659eb--15050519431558438_group">
@@ -71346,8 +71159,8 @@
+ onclick="toggler('20348a5b-5303-4ed5-9035-ab09e06d29e3');" + id="20348a5b-5303-4ed5-9035-ab09e06d29e3_heading">
CTNNB1 inhibits NOTUM.
@@ -71439,7 +71252,7 @@
CTNNB1 inhib
-
+
@@ -71451,8 +71264,8 @@
CTNNB1 inhib
+ onclick="toggler( '20348a5b-5303-4ed5-9035-ab09e06d29e3--24103415494435748' )" + id="20348a5b-5303-4ed5-9035-ab09e06d29e3--24103415494435748_heading">
CTNNB1 inhibits NOTUM. @@ -71552,7 +71365,7 @@
+ id="20348a5b-5303-4ed5-9035-ab09e06d29e3--24103415494435748_group">
@@ -71640,8 +71453,8 @@
+ onclick="toggler('f229a21c-e164-45b6-9362-6bdbaeffb8f8');" + id="f229a21c-e164-45b6-9362-6bdbaeffb8f8_heading">
CTNNB1 increases the amount of NOTUM.
@@ -71733,7 +71546,7 @@
CTNNB1 incre
-
+
@@ -71745,8 +71558,8 @@
CTNNB1 incre
+ onclick="toggler( 'f229a21c-e164-45b6-9362-6bdbaeffb8f8--6000276963605229' )" + id="f229a21c-e164-45b6-9362-6bdbaeffb8f8--6000276963605229_heading">
CTNNB1 increases the amount of NOTUM. @@ -71846,7 +71659,7 @@
+ id="f229a21c-e164-45b6-9362-6bdbaeffb8f8--6000276963605229_group">
@@ -71934,8 +71747,8 @@
+ onclick="toggler('df1e260f-eb72-44d3-bd70-d1714d6f3d6f');" + id="df1e260f-eb72-44d3-bd70-d1714d6f3d6f_heading">
CTNNB1 activates NOTUM.
@@ -72027,7 +71840,7 @@
CTNNB1 activ
-
+
@@ -72039,8 +71852,8 @@
CTNNB1 activ
+ onclick="toggler( 'df1e260f-eb72-44d3-bd70-d1714d6f3d6f-33155590684018632' )" + id="df1e260f-eb72-44d3-bd70-d1714d6f3d6f-33155590684018632_heading">
CTNNB1 activates NOTUM. @@ -72140,7 +71953,7 @@
+ id="df1e260f-eb72-44d3-bd70-d1714d6f3d6f-33155590684018632_group">
@@ -72300,56 +72113,14 @@
padding-right: 1em; } - /* The footer */ - .footer { - position: fixed; /* Make sure the footer is always visible at the bottom */ - bottom: 0; /* Stick it to the bottom of the page */ - left: 0; - right: 20em; - color: #606060; - text-align: left; - padding: 0.5em; - box-shadow: 0 -2px 10px rgba(0, 0, 0, 0.1); - height: 65; - } - - .footer h4, .footer p, .footer a { - font-size: 9pt; - line-height: 1.3; - margin: 0; /* Reduces vertical spacing */ - } - - .side-info-block { - padding: 0em 8px 0em 8px; - margin-bottom: 0; - } - - /* Footer links */ - .il-nav-link { - display: block; - margin: 5px 0; - color: #256DC5; /* Blue color */ - text-decoration: none; - } - - .il-nav-link:hover { - text-decoration: underline; - color: #007bff; - } - - #about-this-project p, #about-this-project a { - font-size: 9pt; - margin-bottom: 0; + .left { + width: 20em; + left: 0; } .right { - width: 20em; /* Sidebar width */ - right: 0; - position: fixed; /* Make sure the sidebar stays on the right */ - top: 0; - bottom: 0; - background-color: #fff; /* White background */ - overflow-y: auto; /* Allow scrolling if content overflows */ + width: 20em; + right: 0; } /* The navigation menu links */ @@ -72360,25 +72131,19 @@
} .side-info h4 { - font-size: 10pt; + font-size: 14pt; display: block; text-decoration: none; - margin-bottom: 0; } - #sources-explanation { - font-size: 10pt; + .side-info-block { + padding: 1em 8px 1em 16px; } .source-desc { border-radius: 4px; - padding: 0em 0em; - font-size: 0.6em; - margin: 1px; - } - - h3.bg-white { - font-size: 13pt; + padding: 0.25em 0.5em 0.25em 0.5em; + margin: 4px; } @@ -73322,7 +73087,7 @@

-
+
@@ -73335,7 +73100,7 @@

-
+
@@ -73347,8 +73112,8 @@

+ onclick="toggler( 'd657cbbd-4b9a-41ab-a4ec-a03285088770--25651917648409213' )" + id="d657cbbd-4b9a-41ab-a4ec-a03285088770--25651917648409213_heading">
CTNNA2 binds CTNNB1. @@ -73453,7 +73218,7 @@
+ id="d657cbbd-4b9a-41ab-a4ec-a03285088770--25651917648409213_group">
@@ -73799,56 +73564,14 @@
padding-right: 1em; } - /* The footer */ - .footer { - position: fixed; /* Make sure the footer is always visible at the bottom */ - bottom: 0; /* Stick it to the bottom of the page */ - left: 0; - right: 20em; - color: #606060; - text-align: left; - padding: 0.5em; - box-shadow: 0 -2px 10px rgba(0, 0, 0, 0.1); - height: 65; - } - - .footer h4, .footer p, .footer a { - font-size: 9pt; - line-height: 1.3; - margin: 0; /* Reduces vertical spacing */ - } - - .side-info-block { - padding: 0em 8px 0em 8px; - margin-bottom: 0; - } - - /* Footer links */ - .il-nav-link { - display: block; - margin: 5px 0; - color: #256DC5; /* Blue color */ - text-decoration: none; - } - - .il-nav-link:hover { - text-decoration: underline; - color: #007bff; - } - - #about-this-project p, #about-this-project a { - font-size: 9pt; - margin-bottom: 0; + .left { + width: 20em; + left: 0; } .right { - width: 20em; /* Sidebar width */ - right: 0; - position: fixed; /* Make sure the sidebar stays on the right */ - top: 0; - bottom: 0; - background-color: #fff; /* White background */ - overflow-y: auto; /* Allow scrolling if content overflows */ + width: 20em; + right: 0; } /* The navigation menu links */ @@ -73859,25 +73582,19 @@
} .side-info h4 { - font-size: 10pt; + font-size: 14pt; display: block; text-decoration: none; - margin-bottom: 0; } - #sources-explanation { - font-size: 10pt; + .side-info-block { + padding: 1em 8px 1em 16px; } .source-desc { border-radius: 4px; - padding: 0em 0em; - font-size: 0.6em; - margin: 1px; - } - - h3.bg-white { - font-size: 13pt; + padding: 0.25em 0.5em 0.25em 0.5em; + margin: 4px; } @@ -74821,7 +74538,7 @@

-
+
@@ -74834,7 +74551,7 @@

-
+
@@ -74846,8 +74563,8 @@

+ onclick="toggler( '46540e94-ff4b-45fd-b368-57a5a1ecea6b-10497479086139712' )" + id="46540e94-ff4b-45fd-b368-57a5a1ecea6b-10497479086139712_heading">
Modified CTNNB1 increases the amount of GLCE. @@ -74947,7 +74664,7 @@
+ id="46540e94-ff4b-45fd-b368-57a5a1ecea6b-10497479086139712_group">
@@ -75086,8 +74803,8 @@
+ onclick="toggler( '46540e94-ff4b-45fd-b368-57a5a1ecea6b--22162766749797540' )" + id="46540e94-ff4b-45fd-b368-57a5a1ecea6b--22162766749797540_heading">
CTNNB1 increases the amount of GLCE. @@ -75182,7 +74899,7 @@
+ id="46540e94-ff4b-45fd-b368-57a5a1ecea6b--22162766749797540_group">
@@ -75280,56 +74997,14 @@
padding-right: 1em; } - /* The footer */ - .footer { - position: fixed; /* Make sure the footer is always visible at the bottom */ - bottom: 0; /* Stick it to the bottom of the page */ - left: 0; - right: 20em; - color: #606060; - text-align: left; - padding: 0.5em; - box-shadow: 0 -2px 10px rgba(0, 0, 0, 0.1); - height: 65; - } - - .footer h4, .footer p, .footer a { - font-size: 9pt; - line-height: 1.3; - margin: 0; /* Reduces vertical spacing */ - } - - .side-info-block { - padding: 0em 8px 0em 8px; - margin-bottom: 0; - } - - /* Footer links */ - .il-nav-link { - display: block; - margin: 5px 0; - color: #256DC5; /* Blue color */ - text-decoration: none; - } - - .il-nav-link:hover { - text-decoration: underline; - color: #007bff; - } - - #about-this-project p, #about-this-project a { - font-size: 9pt; - margin-bottom: 0; + .left { + width: 20em; + left: 0; } .right { - width: 20em; /* Sidebar width */ - right: 0; - position: fixed; /* Make sure the sidebar stays on the right */ - top: 0; - bottom: 0; - background-color: #fff; /* White background */ - overflow-y: auto; /* Allow scrolling if content overflows */ + width: 20em; + right: 0; } /* The navigation menu links */ @@ -75340,25 +75015,19 @@
} .side-info h4 { - font-size: 10pt; + font-size: 14pt; display: block; text-decoration: none; - margin-bottom: 0; } - #sources-explanation { - font-size: 10pt; + .side-info-block { + padding: 1em 8px 1em 16px; } .source-desc { border-radius: 4px; - padding: 0em 0em; - font-size: 0.6em; - margin: 1px; - } - - h3.bg-white { - font-size: 13pt; + padding: 0.25em 0.5em 0.25em 0.5em; + margin: 4px; } @@ -76302,7 +75971,7 @@

-
+
@@ -76315,7 +75984,7 @@

-
+
@@ -76327,8 +75996,8 @@

+ onclick="toggler( '23fc9383-8682-487f-acbd-d5ab8ae222de--32846980916166454' )" + id="23fc9383-8682-487f-acbd-d5ab8ae222de--32846980916166454_heading">
AMOT binds CTNNB1. @@ -76428,7 +76097,7 @@
+ id="23fc9383-8682-487f-acbd-d5ab8ae222de--32846980916166454_group">
@@ -76588,56 +76257,14 @@
padding-right: 1em; } - /* The footer */ - .footer { - position: fixed; /* Make sure the footer is always visible at the bottom */ - bottom: 0; /* Stick it to the bottom of the page */ - left: 0; - right: 20em; - color: #606060; - text-align: left; - padding: 0.5em; - box-shadow: 0 -2px 10px rgba(0, 0, 0, 0.1); - height: 65; - } - - .footer h4, .footer p, .footer a { - font-size: 9pt; - line-height: 1.3; - margin: 0; /* Reduces vertical spacing */ - } - - .side-info-block { - padding: 0em 8px 0em 8px; - margin-bottom: 0; - } - - /* Footer links */ - .il-nav-link { - display: block; - margin: 5px 0; - color: #256DC5; /* Blue color */ - text-decoration: none; - } - - .il-nav-link:hover { - text-decoration: underline; - color: #007bff; - } - - #about-this-project p, #about-this-project a { - font-size: 9pt; - margin-bottom: 0; + .left { + width: 20em; + left: 0; } .right { - width: 20em; /* Sidebar width */ - right: 0; - position: fixed; /* Make sure the sidebar stays on the right */ - top: 0; - bottom: 0; - background-color: #fff; /* White background */ - overflow-y: auto; /* Allow scrolling if content overflows */ + width: 20em; + right: 0; } /* The navigation menu links */ @@ -76648,25 +76275,19 @@
} .side-info h4 { - font-size: 10pt; + font-size: 14pt; display: block; text-decoration: none; - margin-bottom: 0; } - #sources-explanation { - font-size: 10pt; + .side-info-block { + padding: 1em 8px 1em 16px; } .source-desc { border-radius: 4px; - padding: 0em 0em; - font-size: 0.6em; - margin: 1px; - } - - h3.bg-white { - font-size: 13pt; + padding: 0.25em 0.5em 0.25em 0.5em; + margin: 4px; } @@ -77610,7 +77231,7 @@

-
+
@@ -77623,7 +77244,7 @@

-
+
@@ -77635,8 +77256,8 @@

+ onclick="toggler( '4473ba33-c896-4e83-b3a2-438193fae3f0--7151070618082654' )" + id="4473ba33-c896-4e83-b3a2-438193fae3f0--7151070618082654_heading">
APCDD1 binds CTNNB1. @@ -77746,7 +77367,7 @@
+ id="4473ba33-c896-4e83-b3a2-438193fae3f0--7151070618082654_group">
@@ -78154,56 +77775,14 @@
padding-right: 1em; } - /* The footer */ - .footer { - position: fixed; /* Make sure the footer is always visible at the bottom */ - bottom: 0; /* Stick it to the bottom of the page */ - left: 0; - right: 20em; - color: #606060; - text-align: left; - padding: 0.5em; - box-shadow: 0 -2px 10px rgba(0, 0, 0, 0.1); - height: 65; - } - - .footer h4, .footer p, .footer a { - font-size: 9pt; - line-height: 1.3; - margin: 0; /* Reduces vertical spacing */ - } - - .side-info-block { - padding: 0em 8px 0em 8px; - margin-bottom: 0; - } - - /* Footer links */ - .il-nav-link { - display: block; - margin: 5px 0; - color: #256DC5; /* Blue color */ - text-decoration: none; - } - - .il-nav-link:hover { - text-decoration: underline; - color: #007bff; - } - - #about-this-project p, #about-this-project a { - font-size: 9pt; - margin-bottom: 0; + .left { + width: 20em; + left: 0; } .right { - width: 20em; /* Sidebar width */ - right: 0; - position: fixed; /* Make sure the sidebar stays on the right */ - top: 0; - bottom: 0; - background-color: #fff; /* White background */ - overflow-y: auto; /* Allow scrolling if content overflows */ + width: 20em; + right: 0; } /* The navigation menu links */ @@ -78214,25 +77793,19 @@
} .side-info h4 { - font-size: 10pt; + font-size: 14pt; display: block; text-decoration: none; - margin-bottom: 0; } - #sources-explanation { - font-size: 10pt; + .side-info-block { + padding: 1em 8px 1em 16px; } .source-desc { border-radius: 4px; - padding: 0em 0em; - font-size: 0.6em; - margin: 1px; - } - - h3.bg-white { - font-size: 13pt; + padding: 0.25em 0.5em 0.25em 0.5em; + margin: 4px; } @@ -79176,7 +78749,7 @@

-
+
@@ -79189,7 +78762,7 @@

-
+
@@ -79201,8 +78774,8 @@

+ onclick="toggler( 'fb45a3c6-fbb6-41fb-b0ca-2a0ab87797d9--32527223223244217' )" + id="fb45a3c6-fbb6-41fb-b0ca-2a0ab87797d9--32527223223244217_heading">
CTNNB1 activates CALML3. @@ -79302,7 +78875,7 @@
+ id="fb45a3c6-fbb6-41fb-b0ca-2a0ab87797d9--32527223223244217_group">
@@ -79412,10 +78985,19 @@

Bar Charts

Shared Families

+

+ Shared protein families are derived using cypher queries to assess the hierarchical relationships + within the INDRA knowledge base, specifically examining "isa" and "partof" relationships to determine + protein family complexes between the source and target proteins. +

There are no shared families

Shared Upstream Bioentities from Target Proteins

+

+ Shared upstream bioentites explore the intersections between the upstream bioentities of the target proteins + and the bioentities that the target proteins have a direct INDRA relationship with. +

@@ -79542,16 +79124,6 @@

Shared Upstream Bioentities from Target Proteins

- - - - - - - - - - @@ -79560,6 +79132,16 @@

Shared Upstream Bioentities from Target Proteins

+ + + + + + + + + + @@ -79617,12 +79199,22 @@

Boxplots for Shared Go Terms and Bioentities

Shared Pathways Between Source and Enriched Targets Set

+

+ The shared pathways analysis determines the shared Reactome and WikiPathways between the source and + target proteins to reveal potential functional overlaps and shared biological processes through pathway + membership. +

There are no shared pathways

Bar Chart for Frequency of Shared Pathways by Protein

Pathways Chart

Shared Go Terms Between Gene Sets

+

+ The shared GO terms analysis utlizes Gene Ontology (GO) terms associated with the source and target + proteins by finding the intersection of GO terms to explore commonalities in molecular functions, + biological processes, or cellular locations. +

11880hgnc:7611MYOD19.269109e-065.0329620.0196651.706303
12 2692 chebi:17823 calcitriol 0.019665 1.706303
12880hgnc:7611MYOD19.269109e-065.0329620.0196651.706303
13 123