diff --git a/setup.py b/setup.py
index 1349b0a..1442915 100644
--- a/setup.py
+++ b/setup.py
@@ -43,7 +43,7 @@
     install_requires=(
         "google-api-core[grpc] >= 2.8.0, <3.0.0dev",
         "proto-plus >= 1.15.0, <2.0.0dev",
-        "protobuf >= 3.19.0, <4.0.0dev",
+        "protobuf >= 3.19.0, <5.0.0dev",
     ),
     python_requires=">=3.7",
     classifiers=[