diff --git a/CHANGELOG.md b/CHANGELOG.md
index 341042b3..e098689a 100644
--- a/CHANGELOG.md
+++ b/CHANGELOG.md
@@ -1,5 +1,12 @@
 # Changelog
 
+## [0.5.3](https://github.com/googleapis/java-life-sciences/compare/v0.5.2...v0.5.3) (2022-09-09)
+
+
+### Dependencies
+
+* Update dependency com.google.cloud:google-cloud-shared-dependencies to v3.0.2 ([#224](https://github.com/googleapis/java-life-sciences/issues/224)) ([5c85a62](https://github.com/googleapis/java-life-sciences/commit/5c85a626cd030152f2565ed486bac936ec39cc5c))
+
 ## [0.5.2](https://github.com/googleapis/java-life-sciences/compare/v0.5.1...v0.5.2) (2022-08-09)
 
 
diff --git a/google-cloud-life-sciences-bom/pom.xml b/google-cloud-life-sciences-bom/pom.xml
index e93e7e0a..e1cc9458 100644
--- a/google-cloud-life-sciences-bom/pom.xml
+++ b/google-cloud-life-sciences-bom/pom.xml
@@ -3,7 +3,7 @@
   <modelVersion>4.0.0</modelVersion>
   <groupId>com.google.cloud</groupId>
   <artifactId>google-cloud-life-sciences-bom</artifactId>
-  <version>0.5.3-SNAPSHOT</version><!-- {x-version-update:google-cloud-life-sciences:current} -->
+  <version>0.5.3</version><!-- {x-version-update:google-cloud-life-sciences:current} -->
   <packaging>pom</packaging>
   <parent>
     <groupId>com.google.cloud</groupId>
@@ -56,17 +56,17 @@
       <dependency>
         <groupId>com.google.cloud</groupId>
         <artifactId>google-cloud-life-sciences</artifactId>
-        <version>0.5.3-SNAPSHOT</version><!-- {x-version-update:google-cloud-life-sciences:current} -->
+        <version>0.5.3</version><!-- {x-version-update:google-cloud-life-sciences:current} -->
       </dependency>
       <dependency>
         <groupId>com.google.api.grpc</groupId>
         <artifactId>grpc-google-cloud-life-sciences-v2beta</artifactId>
-        <version>0.5.3-SNAPSHOT</version><!-- {x-version-update:grpc-google-cloud-life-sciences-v2beta:current} -->
+        <version>0.5.3</version><!-- {x-version-update:grpc-google-cloud-life-sciences-v2beta:current} -->
       </dependency>
       <dependency>
         <groupId>com.google.api.grpc</groupId>
         <artifactId>proto-google-cloud-life-sciences-v2beta</artifactId>
-        <version>0.5.3-SNAPSHOT</version><!-- {x-version-update:proto-google-cloud-life-sciences-v2beta:current} -->
+        <version>0.5.3</version><!-- {x-version-update:proto-google-cloud-life-sciences-v2beta:current} -->
       </dependency>
     </dependencies>
   </dependencyManagement>
diff --git a/google-cloud-life-sciences/pom.xml b/google-cloud-life-sciences/pom.xml
index 75f5d615..0f07f0c7 100644
--- a/google-cloud-life-sciences/pom.xml
+++ b/google-cloud-life-sciences/pom.xml
@@ -3,7 +3,7 @@
   <modelVersion>4.0.0</modelVersion>
   <groupId>com.google.cloud</groupId>
   <artifactId>google-cloud-life-sciences</artifactId>
-  <version>0.5.3-SNAPSHOT</version><!-- {x-version-update:google-cloud-life-sciences:current} -->
+  <version>0.5.3</version><!-- {x-version-update:google-cloud-life-sciences:current} -->
   <packaging>jar</packaging>
   <name>Google Cloud Life Sciences</name>
   <url>https://github.com/googleapis/java-life-sciences</url>
@@ -11,7 +11,7 @@
   <parent>
     <groupId>com.google.cloud</groupId>
     <artifactId>google-cloud-life-sciences-parent</artifactId>
-    <version>0.5.3-SNAPSHOT</version><!-- {x-version-update:google-cloud-life-sciences:current} -->
+    <version>0.5.3</version><!-- {x-version-update:google-cloud-life-sciences:current} -->
   </parent>
   <properties>
     <site.installationModule>google-cloud-life-sciences</site.installationModule>
diff --git a/grpc-google-cloud-life-sciences-v2beta/pom.xml b/grpc-google-cloud-life-sciences-v2beta/pom.xml
index f9ba4caa..fe007646 100644
--- a/grpc-google-cloud-life-sciences-v2beta/pom.xml
+++ b/grpc-google-cloud-life-sciences-v2beta/pom.xml
@@ -4,13 +4,13 @@
   <modelVersion>4.0.0</modelVersion>
   <groupId>com.google.api.grpc</groupId>
   <artifactId>grpc-google-cloud-life-sciences-v2beta</artifactId>
-  <version>0.5.3-SNAPSHOT</version><!-- {x-version-update:grpc-google-cloud-life-sciences-v2beta:current} -->
+  <version>0.5.3</version><!-- {x-version-update:grpc-google-cloud-life-sciences-v2beta:current} -->
   <name>grpc-google-cloud-life-sciences-v2beta</name>
   <description>GRPC library for google-cloud-life-sciences</description>
   <parent>
     <groupId>com.google.cloud</groupId>
     <artifactId>google-cloud-life-sciences-parent</artifactId>
-    <version>0.5.3-SNAPSHOT</version><!-- {x-version-update:google-cloud-life-sciences:current} -->
+    <version>0.5.3</version><!-- {x-version-update:google-cloud-life-sciences:current} -->
   </parent>
   <dependencies>
     <dependency>
diff --git a/pom.xml b/pom.xml
index d6023331..244c088d 100644
--- a/pom.xml
+++ b/pom.xml
@@ -4,7 +4,7 @@
   <groupId>com.google.cloud</groupId>
   <artifactId>google-cloud-life-sciences-parent</artifactId>
   <packaging>pom</packaging>
-  <version>0.5.3-SNAPSHOT</version><!-- {x-version-update:google-cloud-life-sciences:current} -->
+  <version>0.5.3</version><!-- {x-version-update:google-cloud-life-sciences:current} -->
   <name>Google Cloud Life Sciences Parent</name>
   <url>https://github.com/googleapis/java-life-sciences</url>
   <description>
@@ -60,17 +60,17 @@
       <dependency>
         <groupId>com.google.cloud</groupId>
         <artifactId>google-cloud-life-sciences</artifactId>
-        <version>0.5.3-SNAPSHOT</version><!-- {x-version-update:google-cloud-life-sciences:current} -->
+        <version>0.5.3</version><!-- {x-version-update:google-cloud-life-sciences:current} -->
       </dependency>
       <dependency>
         <groupId>com.google.api.grpc</groupId>
         <artifactId>grpc-google-cloud-life-sciences-v2beta</artifactId>
-        <version>0.5.3-SNAPSHOT</version><!-- {x-version-update:grpc-google-cloud-life-sciences-v2beta:current} -->
+        <version>0.5.3</version><!-- {x-version-update:grpc-google-cloud-life-sciences-v2beta:current} -->
       </dependency>
       <dependency>
         <groupId>com.google.api.grpc</groupId>
         <artifactId>proto-google-cloud-life-sciences-v2beta</artifactId>
-        <version>0.5.3-SNAPSHOT</version><!-- {x-version-update:proto-google-cloud-life-sciences-v2beta:current} -->
+        <version>0.5.3</version><!-- {x-version-update:proto-google-cloud-life-sciences-v2beta:current} -->
       </dependency>
 
       <dependency>
diff --git a/proto-google-cloud-life-sciences-v2beta/pom.xml b/proto-google-cloud-life-sciences-v2beta/pom.xml
index f9af1af0..f26d3e52 100644
--- a/proto-google-cloud-life-sciences-v2beta/pom.xml
+++ b/proto-google-cloud-life-sciences-v2beta/pom.xml
@@ -4,13 +4,13 @@
   <modelVersion>4.0.0</modelVersion>
   <groupId>com.google.api.grpc</groupId>
   <artifactId>proto-google-cloud-life-sciences-v2beta</artifactId>
-  <version>0.5.3-SNAPSHOT</version><!-- {x-version-update:proto-google-cloud-life-sciences-v2beta:current} -->
+  <version>0.5.3</version><!-- {x-version-update:proto-google-cloud-life-sciences-v2beta:current} -->
   <name>proto-google-cloud-life-sciences-v2beta</name>
   <description>Proto library for google-cloud-life-sciences</description>
   <parent>
     <groupId>com.google.cloud</groupId>
     <artifactId>google-cloud-life-sciences-parent</artifactId>
-    <version>0.5.3-SNAPSHOT</version><!-- {x-version-update:google-cloud-life-sciences:current} -->
+    <version>0.5.3</version><!-- {x-version-update:google-cloud-life-sciences:current} -->
   </parent>
   <dependencies>
     <dependency>
diff --git a/versions.txt b/versions.txt
index d53e2540..6beb13be 100644
--- a/versions.txt
+++ b/versions.txt
@@ -1,6 +1,6 @@
 # Format:
 # module:released-version:current-version
 
-google-cloud-life-sciences:0.5.2:0.5.3-SNAPSHOT
-grpc-google-cloud-life-sciences-v2beta:0.5.2:0.5.3-SNAPSHOT
-proto-google-cloud-life-sciences-v2beta:0.5.2:0.5.3-SNAPSHOT
+google-cloud-life-sciences:0.5.3:0.5.3
+grpc-google-cloud-life-sciences-v2beta:0.5.3:0.5.3
+proto-google-cloud-life-sciences-v2beta:0.5.3:0.5.3