diff --git a/.release-please-manifest-individual.json b/.release-please-manifest-individual.json
index be5634ddf6b2..c377ff113aa7 100644
--- a/.release-please-manifest-individual.json
+++ b/.release-please-manifest-individual.json
@@ -8,6 +8,6 @@
   "profiler": "0.3.1",
   "pubsub": "1.28.0",
   "pubsublite": "1.6.0",
-  "spanner": "1.42.0",
+  "spanner": "1.43.0",
   "storage": "1.28.1"
 }
diff --git a/spanner/CHANGES.md b/spanner/CHANGES.md
index 6e4cb0d7665c..27befc8af5ec 100644
--- a/spanner/CHANGES.md
+++ b/spanner/CHANGES.md
@@ -1,5 +1,20 @@
 # Changes
 
+## [1.43.0](https://github.com/googleapis/google-cloud-go/compare/spanner/v1.42.0...spanner/v1.43.0) (2023-01-19)
+
+
+### Features
+
+* **spanner/spansql:** Add support for change stream value_capture_type option ([#7201](https://github.com/googleapis/google-cloud-go/issues/7201)) ([27b3398](https://github.com/googleapis/google-cloud-go/commit/27b33988f078779c2d641f776a11b2095a5ccc51))
+* **spanner/spansql:** Support `default_leader` database option ([#7187](https://github.com/googleapis/google-cloud-go/issues/7187)) ([88adaa2](https://github.com/googleapis/google-cloud-go/commit/88adaa216832467560c19e61528b5ce5f1e5ff76))
+* **spanner:** Add REST client ([06a54a1](https://github.com/googleapis/google-cloud-go/commit/06a54a16a5866cce966547c51e203b9e09a25bc0))
+* **spanner:** Inline begin transaction for ReadWriteTransactions ([#7149](https://github.com/googleapis/google-cloud-go/issues/7149)) ([2ce3606](https://github.com/googleapis/google-cloud-go/commit/2ce360644439a386aeaad7df5f47541667bd621b))
+
+
+### Bug Fixes
+
+* **spanner:** Fix integration tests data race ([#7229](https://github.com/googleapis/google-cloud-go/issues/7229)) ([a741024](https://github.com/googleapis/google-cloud-go/commit/a741024abd6fb1f073831503c2717b2a44226a59))
+
 ## [1.42.0](https://github.com/googleapis/google-cloud-go/compare/spanner/v1.41.0...spanner/v1.42.0) (2022-12-14)
 
 
diff --git a/spanner/internal/version.go b/spanner/internal/version.go
index f37b860085c8..e5b2de09172f 100644
--- a/spanner/internal/version.go
+++ b/spanner/internal/version.go
@@ -15,4 +15,4 @@
 package internal
 
 // Version is the current tagged release of the library.
-const Version = "1.42.0"
+const Version = "1.43.0"