diff --git a/CMakeLists.txt b/CMakeLists.txt
index a4f5a6c4c3..40013e5842 100644
--- a/CMakeLists.txt
+++ b/CMakeLists.txt
@@ -108,6 +108,7 @@ add_subdirectory(pw_result EXCLUDE_FROM_ALL)
 add_subdirectory(pw_ring_buffer EXCLUDE_FROM_ALL)
 add_subdirectory(pw_router EXCLUDE_FROM_ALL)
 add_subdirectory(pw_rpc EXCLUDE_FROM_ALL)
+add_subdirectory(pw_rpc_transport EXCLUDE_FROM_ALL)
 add_subdirectory(pw_snapshot EXCLUDE_FROM_ALL)
 add_subdirectory(pw_span EXCLUDE_FROM_ALL)
 add_subdirectory(pw_status EXCLUDE_FROM_ALL)
diff --git a/pw_rpc_transport/CMakeLists.txt b/pw_rpc_transport/CMakeLists.txt
new file mode 100644
index 0000000000..4672e5df79
--- /dev/null
+++ b/pw_rpc_transport/CMakeLists.txt
@@ -0,0 +1,207 @@
+# Copyright 2023 The Pigweed Authors
+#
+# Licensed under the Apache License, Version 2.0 (the "License"); you may not
+# use this file except in compliance with the License. You may obtain a copy of
+# the License at
+#
+#     https://www.apache.org/licenses/LICENSE-2.0
+#
+# Unless required by applicable law or agreed to in writing, software
+# distributed under the License is distributed on an "AS IS" BASIS, WITHOUT
+# WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied. See the
+# License for the specific language governing permissions and limitations under
+# the License.
+
+include($ENV{PW_ROOT}/pw_build/pigweed.cmake)
+include($ENV{PW_ROOT}/pw_protobuf_compiler/proto.cmake)
+
+pw_add_library(pw_rpc_transport.rpc_transport INTERFACE
+  HEADERS
+    public/pw_rpc_transport/rpc_transport.h
+  PUBLIC_INCLUDES
+    public
+  PUBLIC_DEPS
+    pw_bytes
+    pw_function
+    pw_status
+)
+
+pw_add_library(pw_rpc_transport.service_registry INTERFACE
+  HEADERS
+    public/pw_rpc_transport/service_registry.h
+  PUBLIC_INCLUDES
+    public
+  PUBLIC_DEPS
+    pw_rpc_transport.rpc_transport
+    pw_rpc.client_server
+    pw_span
+    pw_status
+)
+
+pw_add_library(pw_rpc_transport.packet_buffer_queue INTERFACE
+  HEADERS
+    public/pw_rpc_transport/internal/packet_buffer_queue.h
+  PUBLIC_INCLUDES
+    public
+  PUBLIC_DEPS
+    pw_bytes
+    pw_containers
+    pw_result
+    pw_status
+    pw_sync.lock_annotations
+    pw_sync.mutex
+)
+
+pw_add_test(pw_rpc_transport.packet_buffer_queue_test
+  SOURCES
+    internal/packet_buffer_queue_test.cc
+  PRIVATE_DEPS
+    pw_rpc_transport.packet_buffer_queue
+    pw_bytes
+    pw_containers
+    pw_result
+    pw_status
+    pw_sync.lock_annotations
+    pw_sync.mutex
+  GROUPS
+    modules
+    pw_rpc_transport
+)
+
+pw_add_library(pw_rpc_transport.local_rpc_egress STATIC
+  HEADERS
+    public/pw_rpc_transport/local_rpc_egress.h
+  SOURCES
+    local_rpc_egress.cc
+  PUBLIC_INCLUDES
+    public
+  PUBLIC_DEPS
+    pw_rpc_transport.packet_buffer_queue
+    pw_rpc_transport.rpc_transport
+    pw_bytes
+    pw_result
+    pw_rpc.client
+    pw_status
+    pw_sync.thread_notification
+    pw_thread.thread_core
+  PRIVATE_DEPS
+    pw_log
+)
+
+pw_add_test(pw_rpc_transport.local_rpc_egress_test
+  SOURCES
+    local_rpc_egress_test.cc
+  PRIVATE_DEPS
+    pw_rpc_transport.local_rpc_egress
+    pw_rpc_transport.rpc_transport
+    pw_rpc_transport.service_registry
+    pw_rpc_transport.test_protos.pwpb_rpc
+    pw_bytes
+    pw_chrono.system_clock
+    pw_rpc.client_server
+    pw_status
+    pw_sync.counting_semaphore
+    pw_sync.thread_notification
+    pw_thread.sleep
+    pw_thread.thread
+  GROUPS
+    modules
+    pw_rpc_transport
+)
+
+pw_add_library(pw_rpc_transport.hdlc_framing INTERFACE
+  HEADERS
+    public/pw_rpc_transport/hdlc_framing.h
+  PUBLIC_INCLUDES
+    public
+  PUBLIC_DEPS
+    pw_rpc_transport.rpc_transport
+    pw_bytes
+    pw_hdlc.decoder
+    pw_hdlc.encoder
+    pw_result
+    pw_status
+    pw_stream
+)
+
+pw_add_test(pw_rpc_transport.hdlc_framing_test
+  SOURCES
+    hdlc_framing_test.cc
+  PRIVATE_DEPS
+    pw_rpc_transport.hdlc_framing
+    pw_bytes
+    pw_status
+  GROUPS
+    modules
+    pw_rpc_transport
+)
+
+pw_add_library(pw_rpc_transport.simple_framing STATIC
+  HEADERS
+    public/pw_rpc_transport/simple_framing.h
+  SOURCES
+    simple_framing.cc
+  PUBLIC_INCLUDES
+    public
+  PUBLIC_DEPS
+    pw_rpc_transport.rpc_transport
+    pw_assert
+    pw_bytes
+    pw_status
+  PRIVATE_DEPS
+    pw_log
+)
+
+pw_add_test(pw_rpc_transport.simple_framing_test
+  SOURCES
+    simple_framing_test.cc
+  PRIVATE_DEPS
+    pw_rpc_transport.simple_framing
+    pw_bytes
+    pw_log
+    pw_status
+  GROUPS
+    modules
+    pw_rpc_transport
+)
+
+pw_add_library(pw_rpc_transport.egress_ingress STATIC
+  HEADERS
+    public/pw_rpc_transport/egress_ingress.h
+  SOURCES
+    egress_ingress.cc
+  PUBLIC_DEPS
+    pw_rpc_transport.hdlc_framing
+    pw_rpc_transport.simple_framing
+    pw_bytes
+    pw_metric
+    pw_rpc.client
+    pw_status
+  PRIVATE_DEPS
+    pw_log
+)
+
+pw_add_test(pw_rpc_transport.egress_ingress_test
+  SOURCES
+    egress_ingress_test.cc
+  PRIVATE_DEPS
+    pw_rpc_transport.egress_ingress
+    pw_rpc_transport.service_registry
+    pw_rpc_transport.test_protos.pwpb_rpc
+    pw_bytes
+    pw_metric
+    pw_status
+    pw_sync.thread_notification
+  GROUPS
+    modules
+    pw_rpc_transport
+)
+
+pw_proto_library(pw_rpc_transport.test_protos
+  SOURCES
+    internal/test.proto
+  INPUTS
+    internal/test.options
+  PREFIX
+    pw_rpc_transport
+)