diff --git a/glue_jupyter/bqplot/common/tools.py b/glue_jupyter/bqplot/common/tools.py
index 46a0b93c..c301a7dd 100644
--- a/glue_jupyter/bqplot/common/tools.py
+++ b/glue_jupyter/bqplot/common/tools.py
@@ -48,6 +48,8 @@ def activate(self):
 
     def deactivate(self):
         self.viewer._mouse_interact.next = None
+        if hasattr(self, '_roi'):
+            self._roi = None
 
 
 class BqplotSelectionTool(InteractCheckableTool):