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created new terms for #29441
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pgaudet committed Dec 13, 2024
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124 changes: 93 additions & 31 deletions src/ontology/go-edit.obo
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Expand Up @@ -359743,12 +359743,12 @@ creation_date: 2014-05-14T14:32:02Z

[Term]
id: GO:0061628
name: H3K27me3 histone reader activity
name: histone H3K27me3 reader activity
namespace: molecular_function
def: "A histone reader that recognizes a histone H3 trimethylated at lysine 27." [GOC:dph, PMID:23948251]
synonym: "H3-K27me3 modified histone binding" NARROW []
synonym: "H3K27me3 modified histone binding" NARROW []
is_a: GO:0140006 ! H3 histone reader activity
is_a: GO:0140006 ! histone H3 reader activity
relationship: has_part GO:0035064 ! methylated histone binding
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27427" xsd:anyURI

Expand Down Expand Up @@ -364175,11 +364175,11 @@ creation_date: 2018-09-04T13:40:52Z

[Term]
id: GO:0062072
name: H3K9me3 histone reader activity
name: histone H3K9me3 reader activity
namespace: molecular_function
def: "A histone reader that recognizes a histone H3 trimethylated at lysine 9." [PMID:30110338]
synonym: "H3K9me3 modified histone binding" NARROW []
is_a: GO:0140006 ! H3 histone reader activity
is_a: GO:0140006 ! histone H3 reader activity
relationship: has_part GO:0035064 ! methylated histone binding
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27427" xsd:anyURI

Expand Down Expand Up @@ -450214,58 +450214,58 @@ creation_date: 2024-11-12T09:29:56Z

[Term]
id: GO:0140002
name: H3K4me3 histone reader activity
name: histone H3K4me3 reader activity
namespace: molecular_function
def: "A histone reader that recognizes a histone H3 trimethylated at lysine 4." [PMID:15647753, PMID:23318260]
synonym: "H3-K4me3 modified histone binding" NARROW []
synonym: "H3K4me3 modified histone binding" NARROW []
is_a: GO:0140006 ! H3 histone reader activity
is_a: GO:0140006 ! histone H3 reader activity
relationship: has_part GO:0035064 ! methylated histone binding
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29384" xsd:anyURI
created_by: pg
creation_date: 2024-11-29T14:13:16Z

[Term]
id: GO:0140003
name: H3K36me3 histone reader activity
name: histone H3K36me3 reader activity
namespace: molecular_function
def: "A histone reader that recognizes a histone H3 trimethylated at lysine 36." [PMID:15489290, PMID:16364921]
synonym: "H3-K36me3 modified histone binding" NARROW []
synonym: "H3K36me3 modified histone binding" NARROW []
is_a: GO:0140006 ! H3 histone reader activity
is_a: GO:0140006 ! histone H3 reader activity
relationship: has_part GO:0035064 ! methylated histone binding
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29337" xsd:anyURI
created_by: pg
creation_date: 2024-11-29T14:20:22Z

[Term]
id: GO:0140004
name: H3Q5ser histone reader activity
name: histone H3Q5ser reader activity
namespace: molecular_function
def: "A histone reader that recognizes a histone H3 serotonylated at glutamine 5." [PMID:34144982]
synonym: "H3Q5-serotonin histone reader activity" EXACT []
synonym: "H3Q5-serotonin modified histone binding" NARROW []
is_a: GO:0140006 ! H3 histone reader activity
is_a: GO:0140006 ! histone H3 reader activity
relationship: has_part GO:0035064 ! methylated histone binding
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29337" xsd:anyURI
created_by: pg
creation_date: 2024-11-29T14:37:52Z

[Term]
id: GO:0140005
name: H4K20me2 histone reader activity
name: histone H4K20me2 reader activity
namespace: molecular_function
def: "A histone reader that recognizes a histone H4 dimethylated at lysine 20." [PMID:22150589]
synonym: "H4K20me2 modified histone binding" NARROW []
is_a: GO:0140008 ! H4 histone reader activity
is_a: GO:0140008 ! histone H4 reader activity
relationship: has_part GO:0035064 ! methylated histone binding
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24912" xsd:anyURI
created_by: pg
creation_date: 2024-11-29T15:16:39Z

[Term]
id: GO:0140006
name: H3 histone reader activity
name: histone H3 reader activity
namespace: molecular_function
def: "A histone reader that specifically binds either to an unmodified histone H3 or a form modified by a post-translational modification on a specific residue. The most common PTMs on histones are methylation, acetylation and phosphorylation." [PMID:11498575, PMID:25688442, PMID:31082667, PMID:34726351]
is_a: GO:0140566 ! histone reader activity
Expand All @@ -450286,7 +450286,7 @@ creation_date: 2017-03-10T12:47:30Z

[Term]
id: GO:0140008
name: H4 histone reader activity
name: histone H4 reader activity
namespace: molecular_function
def: "A histone reader that specifically binds either to an unmodified histone H4 or a form modified by a post-translational modification on a specific residue. The most common PTMs on histones are methylation, acetylation and phosphorylation." [PMID:11498575, PMID:25688442, PMID:31082667, PMID:34726351]
is_a: GO:0140566 ! histone reader activity
Expand Down Expand Up @@ -450321,23 +450321,23 @@ creation_date: 2017-03-13T11:15:15Z

[Term]
id: GO:0140011
name: H4K12ac histone reader activity
name: histone H4K12ac reader activity
namespace: molecular_function
def: "A histone reader that recognizes a histone H4 acetylated at lysine 12." [PMID:14731392]
synonym: "H4K12ac modified histone binding" NARROW []
is_a: GO:0140008 ! H4 histone reader activity
is_a: GO:0140008 ! histone H4 reader activity
relationship: has_part GO:0035064 ! methylated histone binding
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29384" xsd:anyURI
created_by: pg
creation_date: 2024-12-06T15:08:12Z

[Term]
id: GO:0140012
name: H4K5ac histone reader activity
name: histone H4K5ac reader activity
namespace: molecular_function
def: "A histone reader that recognizes a histone H4 acetylated at lysine 5." [PMID:18406326, PMID:20709061]
synonym: "H4K5ac modified histone binding" NARROW []
is_a: GO:0140008 ! H4 histone reader activity
is_a: GO:0140008 ! histone H4 reader activity
relationship: has_part GO:0035064 ! methylated histone binding
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29384" xsd:anyURI
created_by: pg
Expand Down Expand Up @@ -450372,23 +450372,23 @@ creation_date: 2017-03-23T14:44:23Z

[Term]
id: GO:0140015
name: H3K14ac histone reader activity
name: histone H3K14ac reader activity
namespace: molecular_function
def: "A histone reader that recognizes a histone H3 acetylated at lysine 14." [PMID:30110338]
synonym: "H3K14ac modified histone binding" NARROW []
is_a: GO:0140006 ! H3 histone reader activity
is_a: GO:0140006 ! histone H3 reader activity
relationship: has_part GO:0035064 ! methylated histone binding
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29384" xsd:anyURI
created_by: pg
creation_date: 2024-12-06T15:39:27Z

[Term]
id: GO:0140017
name: H3K18cr histone reader activity
name: histone H3K18cr reader activity
namespace: molecular_function
def: "A histone reader that recognizes a histone H3 crotonylated at lysine 18." [PMID:27105114]
synonym: "H3K18cr modified histone binding" NARROW []
is_a: GO:0140006 ! H3 histone reader activity
is_a: GO:0140006 ! histone H3 reader activity
relationship: has_part GO:0035064 ! methylated histone binding
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29384" xsd:anyURI
created_by: pg
Expand All @@ -450406,11 +450406,11 @@ creation_date: 2017-04-06T12:27:10Z

[Term]
id: GO:0140019
name: H3K9cr histone reader activity
name: histone H3K9cr reader activity
namespace: molecular_function
def: "A histone reader that recognizes a histone H3 crotonylated at lysine 9." [PMID:27105114]
synonym: "H3K9cr modified histone binding" NARROW []
is_a: GO:0140006 ! H3 histone reader activity
is_a: GO:0140006 ! histone H3 reader activity
relationship: has_part GO:0035064 ! methylated histone binding
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29384" xsd:anyURI
created_by: pg
Expand Down Expand Up @@ -450617,11 +450617,11 @@ creation_date: 2017-05-18T06:29:27Z

[Term]
id: GO:0140038
name: H3K27cr histone reader activity
name: histone H3K27cr reader activity
namespace: molecular_function
def: "A histone reader that recognizes a histone H3 crotonylated at lysine 27." [PMID:27105114]
synonym: "H3K27cr modified histone binding" NARROW []
is_a: GO:0140006 ! H3 histone reader activity
is_a: GO:0140006 ! histone H3 reader activity
relationship: has_part GO:0035064 ! methylated histone binding
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29384" xsd:anyURI
created_by: pg
Expand Down Expand Up @@ -450696,23 +450696,23 @@ creation_date: 2017-06-19T09:20:13Z

[Term]
id: GO:0140044
name: H3K18ac histone reader activity
name: histone H3K18ac reader activity
namespace: molecular_function
def: "A histone reader that recognizes a histone H3 acetylated at lysine 18." [PMID:30110338]
synonym: "H3K18ac modified histone binding" NARROW []
is_a: GO:0140006 ! H3 histone reader activity
is_a: GO:0140006 ! histone H3 reader activity
relationship: has_part GO:0035064 ! methylated histone binding
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29384" xsd:anyURI
created_by: pg
creation_date: 2024-12-06T15:47:07Z

[Term]
id: GO:0140046
name: H4K16ac histone reader activity
name: histone H4K16ac reader activity
namespace: molecular_function
def: "A histone reader that recognizes a histone H4 acetylated at lysine 16." [PMID:16085498]
synonym: "H4K16ac modified histone binding" NARROW []
is_a: GO:0140008 ! H4 histone reader activity
is_a: GO:0140008 ! histone H4 reader activity
relationship: has_part GO:0035064 ! methylated histone binding
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29384" xsd:anyURI
created_by: pg
Expand Down Expand Up @@ -450800,6 +450800,31 @@ intersection_of: occurs_in GO:0005739 ! mitochondrion
created_by: pg
creation_date: 2017-06-26T10:57:45Z

[Term]
id: GO:0140054
name: histone H2A reader activity
namespace: molecular_function
def: "A histone reader that specifically binds either to an unmodified histone H2A or a form modified by a post-translational modification on a specific residue. The most common PTMs on histones are methylation, acetylation and phosphorylation." [PMID:11498575, PMID:25688442, PMID:31082667, PMID:34726351]
synonym: "histone H2A reader" EXACT []
is_a: GO:0140566 ! histone reader activity
relationship: has_part GO:0042393 ! histone binding
relationship: occurs_in GO:0000786 ! nucleosome
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29441" xsd:anyURI
created_by: pg
creation_date: 2024-12-13T14:14:39Z

[Term]
id: GO:0140055
name: histone H4K8ac reader activity
namespace: molecular_function
def: "A histone reader that recognizes a histone H4 acetylated at lysine 8." [GOC:pg]
synonym: "H4K8ac modified histone binding" NARROW []
is_a: GO:0140008 ! histone H4 reader activity
relationship: has_part GO:0035064 ! methylated histone binding
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29441" xsd:string
created_by: pg
creation_date: 2024-12-13T14:54:04Z

[Term]
id: GO:0140056
name: organelle localization by membrane tethering
Expand Down Expand Up @@ -450880,6 +450905,18 @@ replaced_by: GO:0070579
created_by: pg
creation_date: 2017-07-20T09:57:16Z

[Term]
id: GO:0140063
name: unmodified histone reader activity
namespace: molecular_function
def: "A histone reader that specifically binds either to an unmodified histone." [GOC:pg]
comment: Curator note: To annotate the specific histone recognized, use 'has input' extension.
is_a: GO:0140566 ! histone reader activity
relationship: has_part GO:0035064 ! methylated histone binding
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29441" xsd:string
created_by: pg
creation_date: 2024-12-13T14:55:58Z

[Term]
id: GO:0140064
name: peptide crotonyltransferase activity
Expand Down Expand Up @@ -450959,6 +450996,31 @@ property_value: term_tracker_item "https://github.com/geneontology/go-ontology/i
created_by: pg
creation_date: 2022-09-27T11:35:19Z

[Term]
id: GO:0140071
name: histone H2B reader activity
namespace: molecular_function
def: "A histone reader that specifically binds either to an unmodified histone H2B or a form modified by a post-translational modification on a specific residue. The most common PTMs on histones are methylation, acetylation and phosphorylation." [PMID:11498575, PMID:25688442, PMID:31082667, PMID:34726351]
synonym: "histone H2A reader" EXACT []
is_a: GO:0140566 ! histone reader activity
relationship: has_part GO:0042393 ! histone binding
relationship: occurs_in GO:0000786 ! nucleosome
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29441" xsd:anyURI
created_by: pg
creation_date: 2024-12-13T14:57:55Z

[Term]
id: GO:0140072
name: histone H3K9ac reader activity
namespace: molecular_function
def: "A histone reader that recognizes a histone H3 acetylated at lysine 9." [GOC:pg]
synonym: "H3K9ac modified histone binding" NARROW []
is_a: GO:0140006 ! histone H3 reader activity
relationship: has_part GO:0035064 ! methylated histone binding
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29441" xsd:string
created_by: pg
creation_date: 2024-12-13T14:59:50Z

[Term]
id: GO:0140074
name: cardiac endothelial to mesenchymal transition
Expand Down Expand Up @@ -455250,7 +455312,7 @@ namespace: molecular_function
def: "A chromatin adaptor activity that brings together a protein and a specific form of histone, either modified by a post-translational modification, or the unmodified form. Histone readers have roles in many processes, including in centromere function or in modulating the accessibility of cis-regulatory regions to the transcription machinery." [PMID:11498575, PMID:25688442, PMID:31082667, PMID:34726351]
synonym: "epigenetic reader" BROAD []
synonym: "histone reader" EXACT []
is_a: GO:0140463 ! chromatin-protein adaptor activity
is_a: GO:0030674 ! protein-macromolecule adaptor activity
relationship: has_part GO:0042393 ! histone binding
relationship: occurs_in GO:0000786 ! nucleosome
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/20551" xsd:anyURI
Expand Down

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