From 618b7467a15aacf17dbd7544af7fced7d802f354 Mon Sep 17 00:00:00 2001 From: suzialeksander Date: Tue, 3 Sep 2024 13:36:56 -0600 Subject: [PATCH] Update ribbon.md Adding QuickGO --- _docs/ribbon.md | 12 ++++++++++-- 1 file changed, 10 insertions(+), 2 deletions(-) diff --git a/_docs/ribbon.md b/_docs/ribbon.md index ff427c76..7a7ab2f3 100644 --- a/_docs/ribbon.md +++ b/_docs/ribbon.md @@ -47,12 +47,20 @@ The summaries provided by the GO Ribbon can be used to quickly highlight the sim The visual summary of a gene set through the Ribbon can help identify shared functions or sub clusters of genes exhibiting different behaviors. -## GO Ribbon and GO Enrichment -It's however important to remind that the GO Ribbon is designed to provide a visual summary and a simpler way to navigate GO annotations. For gene sets, the GO Ribbon will show the functions shared between genes, but it will not inform on the statistical relevance (over / under representation) of such functions in the gene set. Statistical significance and bias of biological functions have to be examined through [over representation tests and enrichment analysis](/docs/go-enrichment-analysis/). +## GO Ribbon is not GO Enrichment +The GO Ribbon is designed to provide a visual summary and a simpler way to navigate GO annotations. For gene sets, the GO Ribbon will show the functions shared between genes, but it will *not* inform on the statistical relevance (over/under representation) of such functions in the gene set. Statistical significance and bias of biological functions have to be examined through [over representation tests and enrichment analysis](/docs/go-enrichment-analysis/). + + As an example, the [GO COVID-19 page](/covid-19.html) illustrates how both the Ribbon and enrichment analysis can be used together. +## Other ways to access GO Ribbons +GO Ribbons specifically for eukaryotic cellular processes, plants, and prokaryotes are available on the [QuickGO slimming page](https://www.ebi.ac.uk/QuickGO/slimming){:target="blank"}, as is a FlyBase-specific ribbon. To access these, click the "Explore biology" box on the [QuickGO home page](https://www.ebi.ac.uk/QuickGO/). Select a ribbon in the dropdown and click the "Add terms to selection" button, then Apply. You can filter the resulting GO annotations by IDs, taxon, and more. + + +![GO Ribbons at QuickGO](/assets/GORibbonQuickGO.png) +# Technical Information ## Authorized IDs The gene IDs generally recognized within GO are the ones provided by the Model Organism Database (MODs) in their [GPI file](/docs/gene-product-information-gpi-format/).