diff --git a/src/broker/content-cache.c b/src/broker/content-cache.c
index d2ef184bcd36..87510606167f 100644
--- a/src/broker/content-cache.c
+++ b/src/broker/content-cache.c
@@ -524,6 +524,18 @@ static void cache_store_continuation (flux_future_t *f, void *arg)
     cache_resume_flush (cache);
 }
 
+/* Issue #4482, there is a small chance a dirty entry could be added
+ * to the flush list twice which can lead to list corruption.  As an
+ * extra measure, perform a delete from the list first.  If the node
+ * is not on the list, the delete is a no-op.
+ */
+static void flush_list_append (struct content_cache *cache,
+                               struct cache_entry *e)
+{
+    list_del (&e->list);
+    list_add_tail (&cache->flush, &e->list);
+}
+
 static int cache_store (struct content_cache *cache, struct cache_entry *e)
 {
     flux_future_t *f;
@@ -535,7 +547,7 @@ static int cache_store (struct content_cache *cache, struct cache_entry *e)
         return 0;
     if (cache->rank == 0) {
         if (cache->flush_batch_count >= cache->flush_batch_limit) {
-            list_add_tail (&cache->flush, &e->list);
+            flush_list_append (cache, e);
             return 0;
         }
         flags = CONTENT_FLAG_CACHE_BYPASS;
@@ -595,7 +607,7 @@ static void content_store_request (flux_t *h, flux_msg_handler_t *mh,
          * during purge or dropcache, so this does not alter
          * behavior */
         if (cache->rank == 0 && !cache->backing)
-            list_add_tail (&cache->flush, &e->list);
+            flush_list_append (cache, e);
     }
     if (flux_respond_raw (h, msg, hash, hash_size) < 0)
         flux_log_error (h, "content store: flux_respond_raw");
diff --git a/t/Makefile.am b/t/Makefile.am
index 87e073c36a95..dda1cd80a073 100644
--- a/t/Makefile.am
+++ b/t/Makefile.am
@@ -260,9 +260,11 @@ EXTRA_DIST= \
 	rc/rc1-kvs \
 	rc/rc1-testenv \
 	rc/rc1-job \
+	rc/rc1-issue4482 \
 	rc/rc3-kvs \
 	rc/rc3-testenv \
 	rc/rc3-job \
+	rc/rc3-issue4482 \
 	shell/input \
 	shell/output \
 	shell/initrc/tests \
@@ -307,6 +309,7 @@ dist_check_SCRIPTS = \
 	issues/t4379-dirty-cache-entries-flush.sh \
 	issues/t4413-empty-eventlog.sh \
 	issues/t4465-job-list-use-after-free.sh \
+	issues/t4482-flush-list-corruption.sh \
 	python/__init__.py \
 	python/subflux.py \
 	python/tap \
diff --git a/t/issues/t4482-flush-list-corruption.sh b/t/issues/t4482-flush-list-corruption.sh
new file mode 100755
index 000000000000..0ca63bba5e20
--- /dev/null
+++ b/t/issues/t4482-flush-list-corruption.sh
@@ -0,0 +1,52 @@
+#!/bin/sh -e
+
+# How this test works
+#
+# use rc1 script that does not load content-sqlite
+#
+# add some unique data to the kvs, we do multiple puts to build up
+# a decent length internal list of flushable cache entries.
+#
+# drop kvs cache, this will force future KVS puts of identical data to
+# be sent to the content-cache
+#
+# write the same data again, if error present internal flush list will
+# be messed up and length of flush list < number of dirty entries
+# (acct_dirty).
+#
+# before fix, flux content flush will hang b/c number of dirty entries
+# (acct_dirty) never reaches zero.
+
+cat <<-EOF >t4482.sh
+#!/bin/sh -e
+
+flux kvs put issue4482A.a="abcdefghijk"
+flux kvs put issue4482A.b="lmnopqrstuv"
+flux kvs put issue4482A.c="wxyz0123456"
+flux kvs put issue4482A.d="7890ABCDEFG"
+flux kvs put issue4482A.e="HIJKLMNOPQR"
+flux kvs put issue4482A.f="STUVWXYZ!!!"
+flux kvs put issue4482A.g="<<<<<:>>>>>"
+
+flux kvs dropcache
+
+flux kvs put issue4482B.a="abcdefghijk"
+flux kvs put issue4482B.b="lmnopqrstuv"
+flux kvs put issue4482B.c="wxyz0123456"
+flux kvs put issue4482B.d="7890ABCDEFG"
+flux kvs put issue4482B.e="HIJKLMNOPQR"
+flux kvs put issue4482B.f="STUVWXYZ!!!"
+flux kvs put issue4482B.g="<<<<<:>>>>>"
+
+flux module load content-sqlite
+
+flux content flush
+
+EOF
+
+chmod +x t4482.sh
+
+flux start -s 1 \
+    -o,--setattr=broker.rc1_path=${FLUX_SOURCE_DIR}/t/rc/rc1-issue4482 \
+    -o,--setattr=broker.rc3_path=${FLUX_SOURCE_DIR}/t/rc/rc3-issue4482 \
+    ./t4482.sh
diff --git a/t/rc/rc1-issue4482 b/t/rc/rc1-issue4482
new file mode 100755
index 000000000000..9d28bc6f222d
--- /dev/null
+++ b/t/rc/rc1-issue4482
@@ -0,0 +1,6 @@
+#!/bin/bash -e
+
+# For issue4482 - assumes test size of 1
+flux module load kvs
+flux module load kvs-watch
+flux module load heartbeat
diff --git a/t/rc/rc3-issue4482 b/t/rc/rc3-issue4482
new file mode 100755
index 000000000000..798c81d6014a
--- /dev/null
+++ b/t/rc/rc3-issue4482
@@ -0,0 +1,8 @@
+#!/bin/bash -e
+
+# For issue4482 - assumes test size of 1
+flux module remove -f heartbeat
+flux module remove -f kvs-watch
+flux module remove -f kvs
+# content-sqlite loaded in test
+flux module remove -f content-sqlite