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DESCRIPTION
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DESCRIPTION
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Package: RMAFster
Title: Calculate and Explote RNA Mutant Allele Frequencies
Version: 0.0.0.9000
Authors@R:
person(given = "Franco",
family = "Caramia",
role = c("aut", "cre"),
email = "[email protected]",
comment = c(ORCID = "0000-0002-5086-2544"))
Maintainer: Franco Caramia <[email protected]>
Description: RMAFster calculates and explores RNA Mutated Allele Frequencies (RMAFs) from Bam Files.
It searches for previously detected DNA mutations in mRNA and calculates statistics under 2 hypotheses:
Mutations are expressed in a bi-allelic manner and DNA Variant Allele Frequencies (VAF) are proportional
to RMAFs.
License: MIT + file LICENSE
Encoding: UTF-8
LazyData: true
Roxygen: list(markdown = TRUE)
RoxygenNote: 7.1.1
SystemRequirements: Python (>= 3.0.0)
Imports:
data.table,
dplyr,
reticulate,
ggplot2,
patchwork,
reshape2,
ggpubr,
lifecycle
Config/reticulate:
list(
packages = list(
list(package = "pysam", pip = TRUE)
)
)
Suggests:
testthat
RdMacros:
lifecycle