diff --git a/packages/react-is/README.md b/packages/react-is/README.md
index d255977618178..c446e89c6b0fe 100644
--- a/packages/react-is/README.md
+++ b/packages/react-is/README.md
@@ -40,7 +40,6 @@ ReactIs.isValidElementType(FunctionComponent); // true
 ReactIs.isValidElementType(ForwardRefComponent); // true
 ReactIs.isValidElementType(Context.Provider); // true
 ReactIs.isValidElementType(Context.Consumer); // true
-ReactIs.isValidElementType(React.createFactory("div")); // true
 ```
 
 ### Determining an Element's Type
diff --git a/packages/react-is/src/__tests__/ReactIs-test.js b/packages/react-is/src/__tests__/ReactIs-test.js
index 5b63eebd529fd..f9d9dc923cc23 100644
--- a/packages/react-is/src/__tests__/ReactIs-test.js
+++ b/packages/react-is/src/__tests__/ReactIs-test.js
@@ -67,18 +67,6 @@ describe('ReactIs', () => {
     expect(ReactIs.isValidElementType(MemoComponent)).toEqual(true);
     expect(ReactIs.isValidElementType(Context.Provider)).toEqual(true);
     expect(ReactIs.isValidElementType(Context.Consumer)).toEqual(true);
-    if (!__EXPERIMENTAL__) {
-      let factory;
-      expect(() => {
-        factory = React.createFactory('div');
-      }).toWarnDev(
-        'Warning: React.createFactory() is deprecated and will be removed in a ' +
-          'future major release. Consider using JSX or use React.createElement() ' +
-          'directly instead.',
-        {withoutStack: true},
-      );
-      expect(ReactIs.isValidElementType(factory)).toEqual(true);
-    }
     expect(ReactIs.isValidElementType(React.Fragment)).toEqual(true);
     expect(ReactIs.isValidElementType(React.StrictMode)).toEqual(true);
     expect(ReactIs.isValidElementType(React.Suspense)).toEqual(true);
diff --git a/packages/react/index.classic.fb.js b/packages/react/index.classic.fb.js
index 949a23c70ab33..c8a3a6012a27a 100644
--- a/packages/react/index.classic.fb.js
+++ b/packages/react/index.classic.fb.js
@@ -20,7 +20,6 @@ export {
   cloneElement,
   createContext,
   createElement,
-  createFactory,
   createRef,
   use,
   forwardRef,
diff --git a/packages/react/index.experimental.js b/packages/react/index.experimental.js
index 30472a43d33f6..1adaed959e512 100644
--- a/packages/react/index.experimental.js
+++ b/packages/react/index.experimental.js
@@ -20,7 +20,6 @@ export {
   cloneElement,
   createContext,
   createElement,
-  createFactory,
   createRef,
   use,
   forwardRef,
diff --git a/packages/react/index.js b/packages/react/index.js
index a3bd5737066d9..2f267f6eeb0c0 100644
--- a/packages/react/index.js
+++ b/packages/react/index.js
@@ -41,7 +41,6 @@ export {
   cloneElement,
   createContext,
   createElement,
-  createFactory,
   createRef,
   use,
   forwardRef,
diff --git a/packages/react/index.stable.js b/packages/react/index.stable.js
index ebab580542b24..5e356cf698987 100644
--- a/packages/react/index.stable.js
+++ b/packages/react/index.stable.js
@@ -20,7 +20,6 @@ export {
   cloneElement,
   createContext,
   createElement,
-  createFactory,
   createRef,
   use,
   forwardRef,
diff --git a/packages/react/src/ReactClient.js b/packages/react/src/ReactClient.js
index 711afdad469de..83bcdcc8226a2 100644
--- a/packages/react/src/ReactClient.js
+++ b/packages/react/src/ReactClient.js
@@ -27,7 +27,6 @@ import {createRef} from './ReactCreateRef';
 import {forEach, map, count, toArray, only} from './ReactChildren';
 import {
   createElement,
-  createFactory,
   cloneElement,
   isValidElement,
 } from './jsx/ReactJSXElement';
@@ -62,7 +61,6 @@ import {
   useOptimistic,
   useActionState,
 } from './ReactHooks';
-
 import ReactSharedInternals from './ReactSharedInternalsClient';
 import {startTransition} from './ReactStartTransition';
 import {act} from './ReactAct';
@@ -111,8 +109,6 @@ export {
   isValidElement,
   ReactVersion as version,
   ReactSharedInternals as __SECRET_INTERNALS_DO_NOT_USE_OR_YOU_WILL_BE_FIRED,
-  // Deprecated behind disableCreateFactory
-  createFactory,
   // Concurrent Mode
   useTransition,
   startTransition,
diff --git a/packages/react/src/__tests__/ReactElementValidator-test.internal.js b/packages/react/src/__tests__/ReactElementValidator-test.internal.js
index b1d7257ccdb10..d3e2ed78e5ba6 100644
--- a/packages/react/src/__tests__/ReactElementValidator-test.internal.js
+++ b/packages/react/src/__tests__/ReactElementValidator-test.internal.js
@@ -331,34 +331,6 @@ describe('ReactElementValidator', () => {
     );
   });
 
-  if (!__EXPERIMENTAL__) {
-    it('should warn when accessing .type on an element factory', () => {
-      function TestComponent() {
-        return <div />;
-      }
-
-      let TestFactory;
-
-      expect(() => {
-        TestFactory = React.createFactory(TestComponent);
-      }).toWarnDev(
-        'Warning: React.createFactory() is deprecated and will be removed in a ' +
-          'future major release. Consider using JSX or use React.createElement() ' +
-          'directly instead.',
-        {withoutStack: true},
-      );
-
-      expect(() => TestFactory.type).toWarnDev(
-        'Warning: Factory.type is deprecated. Access the class directly before ' +
-          'passing it to createFactory.',
-        {withoutStack: true},
-      );
-
-      // Warn once, not again
-      expect(TestFactory.type).toBe(TestComponent);
-    });
-  }
-
   it('does not warn when using DOM node as children', async () => {
     class DOMContainer extends React.Component {
       ref;
diff --git a/packages/react/src/jsx/ReactJSXElement.js b/packages/react/src/jsx/ReactJSXElement.js
index e85e2cfc87e7d..3a0027c2b6a32 100644
--- a/packages/react/src/jsx/ReactJSXElement.js
+++ b/packages/react/src/jsx/ReactJSXElement.js
@@ -757,49 +757,6 @@ export function createElement(type, config, children) {
   return element;
 }
 
-let didWarnAboutDeprecatedCreateFactory = false;
-
-/**
- * Return a function that produces ReactElements of a given type.
- * See https://reactjs.org/docs/react-api.html#createfactory
- */
-export function createFactory(type) {
-  const factory = createElement.bind(null, type);
-  // Expose the type on the factory and the prototype so that it can be
-  // easily accessed on elements. E.g. `<Foo />.type === Foo`.
-  // This should not be named `constructor` since this may not be the function
-  // that created the element, and it may not even be a constructor.
-  // Legacy hook: remove it
-  factory.type = type;
-
-  if (__DEV__) {
-    if (!didWarnAboutDeprecatedCreateFactory) {
-      didWarnAboutDeprecatedCreateFactory = true;
-      console.warn(
-        'React.createFactory() is deprecated and will be removed in ' +
-          'a future major release. Consider using JSX ' +
-          'or use React.createElement() directly instead.',
-      );
-    }
-    // Legacy hook: remove it
-    Object.defineProperty(factory, 'type', {
-      enumerable: false,
-      get: function () {
-        console.warn(
-          'Factory.type is deprecated. Access the class directly ' +
-            'before passing it to createFactory.',
-        );
-        Object.defineProperty(this, 'type', {
-          value: type,
-        });
-        return type;
-      },
-    });
-  }
-
-  return factory;
-}
-
 export function cloneAndReplaceKey(oldElement, newKey) {
   return ReactElement(
     oldElement.type,