diff --git a/components/openthread/lib b/components/openthread/lib
index 31136c18c6ed..7d57b18006da 160000
--- a/components/openthread/lib
+++ b/components/openthread/lib
@@ -1 +1 @@
-Subproject commit 31136c18c6ed890f4a100f7713e3b04ae07702c6
+Subproject commit 7d57b18006da6e182ddb87698abdced1566f3b56
diff --git a/examples/openthread/.build-test-rules.yml b/examples/openthread/.build-test-rules.yml
index 069989ac1d6a..c43a8e5efe6f 100644
--- a/examples/openthread/.build-test-rules.yml
+++ b/examples/openthread/.build-test-rules.yml
@@ -1,12 +1,8 @@
 # Documentation: .gitlab/ci/README.md#manifest-file-to-control-the-buildtest-apps
 
 examples/openthread/ot_br:
-  disable:
-    - if: IDF_TARGET == "esp32c2" or IDF_TARGET == "esp32c6"
-      temporary: true
-      reason: target(s) not supported yet
   disable_test:
-    - if: IDF_TARGET in ["esp32", "esp32c3", "esp32s2", "esp32c6"]
+    - if: IDF_TARGET in ["esp32", "esp32c3", "esp32c2", "esp32c6", "esp32s2"]
       temporary: true
       reason: only test on esp32s3
 
diff --git a/examples/openthread/ot_br/README.md b/examples/openthread/ot_br/README.md
index 7e07ddd856a3..2286a0148925 100644
--- a/examples/openthread/ot_br/README.md
+++ b/examples/openthread/ot_br/README.md
@@ -1,5 +1,5 @@
-| Supported Targets | ESP32 | ESP32-C3 | ESP32-S2 | ESP32-S3 |
-| ----------------- | ----- | -------- | -------- | -------- |
+| Supported Targets | ESP32 | ESP32-C2 | ESP32-C3 | ESP32-C6 | ESP32-S2 | ESP32-S3 |
+| ----------------- | ----- | -------- | -------- | -------- | -------- | -------- |
 
 # OpenThread Border Router Example
 
diff --git a/examples/openthread/ot_br/main/esp_ot_br.c b/examples/openthread/ot_br/main/esp_ot_br.c
index 8bbb44ed864c..6d50eedbbf62 100644
--- a/examples/openthread/ot_br/main/esp_ot_br.c
+++ b/examples/openthread/ot_br/main/esp_ot_br.c
@@ -205,7 +205,12 @@ void app_main(void)
     // * task queue
     // * border router
     esp_vfs_eventfd_config_t eventfd_config = {
+#if CONFIG_OPENTHREAD_RADIO_NATIVE
+        // * radio driver (A native radio device needs a eventfd for radio driver.)
+        .max_fds = 4,
+#else
         .max_fds = 3,
+#endif
     };
     ESP_ERROR_CHECK(esp_vfs_eventfd_register(&eventfd_config));
 
diff --git a/examples/openthread/ot_br/main/esp_ot_config.h b/examples/openthread/ot_br/main/esp_ot_config.h
index 71c961e37005..cdf033f98579 100644
--- a/examples/openthread/ot_br/main/esp_ot_config.h
+++ b/examples/openthread/ot_br/main/esp_ot_config.h
@@ -16,6 +16,12 @@
 
 #include "esp_openthread_types.h"
 
+#if CONFIG_OPENTHREAD_RADIO_NATIVE
+#define ESP_OPENTHREAD_DEFAULT_RADIO_CONFIG()              \
+    {                                                      \
+        .radio_mode = RADIO_MODE_NATIVE,                   \
+    }
+#else
 #define ESP_OPENTHREAD_DEFAULT_RADIO_CONFIG()                        \
     {                                                                \
         .radio_mode = RADIO_MODE_UART_RCP,                           \
@@ -35,6 +41,13 @@
             .tx_pin = 5,                                             \
         },                                                           \
     }
+#endif
+
+#if CONFIG_IDF_TARGET_ESP32C2 && CONFIG_XTAL_FREQ_26
+#define HOST_BAUD_RATE 74880
+#else
+#define HOST_BAUD_RATE 115200
+#endif
 
 #define ESP_OPENTHREAD_DEFAULT_HOST_CONFIG()                    \
     {                                                           \
@@ -43,7 +56,7 @@
             .port = 0,                                          \
             .uart_config =                                      \
                 {                                               \
-                    .baud_rate = 115200,                        \
+                    .baud_rate = HOST_BAUD_RATE,                \
                     .data_bits = UART_DATA_8_BITS,              \
                     .parity = UART_PARITY_DISABLE,              \
                     .stop_bits = UART_STOP_BITS_1,              \