diff --git a/README.md b/README.md
index c9da5e48c..78cb0807e 100644
--- a/README.md
+++ b/README.md
@@ -99,6 +99,7 @@ Starlette does not have any hard dependencies, but the following are optional:
 * [`pyyaml`][pyyaml] - Required for `SchemaGenerator` support.
 * [`graphene`][graphene] - Required for `GraphQLApp` support.
 * [`ujson`][ujson] - Required if you want to use `UJSONResponse`.
+* [`orjson`][orjson] - Required if you want to use `ORJSONResponse`.
 
 You can install all of these with `pip3 install starlette[full]`.
 
diff --git a/docs/responses.md b/docs/responses.md
index bf357a355..ffa2dfc2c 100644
--- a/docs/responses.md
+++ b/docs/responses.md
@@ -112,6 +112,25 @@ async def app(scope, receive, send):
     await response(scope, receive, send)
 ```
 
+### ORJSONResponse
+
+Another JSON response class that uses the optimised `orjson` library for serialisation.
+
+`orjson` is a fast, correct JSON library for Python. It
+[benchmarks](https://github.com/ijl/orjson#performance) as the fastest Python
+library for JSON and is more correct than the standard json library or other
+third-party libraries.
+
+```python
+from starlette.responses import ORJSONResponse
+
+
+async def app(scope, receive, send):
+    assert scope['type'] == 'http'
+    response = ORJSONResponse({'hello': 'world'})
+    await response(scope, receive, send)
+```
+
 ### RedirectResponse
 
 Returns an HTTP redirect. Uses a 307 status code by default.
diff --git a/requirements.txt b/requirements.txt
index dc18d7897..0ea5af4ac 100644
--- a/requirements.txt
+++ b/requirements.txt
@@ -7,6 +7,7 @@ python-multipart
 pyyaml
 requests
 ujson
+orjson
 
 # Testing
 autoflake
diff --git a/setup.py b/setup.py
index de80e0ef9..89651de29 100644
--- a/setup.py
+++ b/setup.py
@@ -58,6 +58,7 @@ def get_packages(package):
             "pyyaml",
             "requests",
             "ujson",
+            "orjson",
         ]
     },
     classifiers=[
diff --git a/starlette/responses.py b/starlette/responses.py
index 143e9e014..3f66b09a5 100644
--- a/starlette/responses.py
+++ b/starlette/responses.py
@@ -29,6 +29,11 @@
 except ImportError:  # pragma: nocover
     ujson = None  # type: ignore
 
+try:
+    import orjson
+except ImportError:  # pragma: nocover
+    orjson = None  # type: ignore
+
 
 class Response:
     media_type = None
@@ -171,6 +176,14 @@ def render(self, content: typing.Any) -> bytes:
         return ujson.dumps(content, ensure_ascii=False).encode("utf-8")
 
 
+class ORJSONResponse(JSONResponse):
+    media_type = "application/json"
+
+    def render(self, content: typing.Any) -> bytes:
+        assert orjson is not None, "orjson must be installed to use ORJSONResponse"
+        return orjson.dumps(content)
+
+
 class RedirectResponse(Response):
     def __init__(
         self, url: typing.Union[str, URL], status_code: int = 307, headers: dict = None
diff --git a/tests/test_responses.py b/tests/test_responses.py
index a28bbbf52..f38b88d67 100644
--- a/tests/test_responses.py
+++ b/tests/test_responses.py
@@ -13,6 +13,7 @@
     Response,
     StreamingResponse,
     UJSONResponse,
+    ORJSONResponse,
 )
 from starlette.testclient import TestClient
 
@@ -47,6 +48,16 @@ async def app(scope, receive, send):
     assert response.json() == {"hello": "world"}
 
 
+def test_orjson_response():
+    async def app(scope, receive, send):
+        response = ORJSONResponse({"hello": "world"})
+        await response(scope, receive, send)
+
+    client = TestClient(app)
+    response = client.get("/")
+    assert response.json() == {"hello": "world"}
+
+
 def test_json_none_response():
     async def app(scope, receive, send):
         response = JSONResponse(None)