diff --git a/httpx/_api.py b/httpx/_api.py
index 985e2ab938..8cfaf6dfda 100644
--- a/httpx/_api.py
+++ b/httpx/_api.py
@@ -47,7 +47,7 @@ def request(
     `HEAD`, `POST`, `PUT`, `PATCH`, or `DELETE`.
     * **url** - URL for the new `Request` object.
     * **params** - *(optional)* Query parameters to include in the URL, as a
-    string, dictionary, or list of two-tuples.
+    string, dictionary, or sequence of two-tuples.
     * **content** - *(optional)* Binary content to include in the body of the
     request, as bytes or a byte iterator.
     * **data** - *(optional)* Form data to include in the body of the request,
diff --git a/httpx/_client.py b/httpx/_client.py
index 0ae5f2b1fa..4f457c79dc 100644
--- a/httpx/_client.py
+++ b/httpx/_client.py
@@ -520,7 +520,7 @@ class Client(BaseClient):
     * **auth** - *(optional)* An authentication class to use when sending
     requests.
     * **params** - *(optional)* Query parameters to include in request URLs, as
-    a string, dictionary, or list of two-tuples.
+    a string, dictionary, or sequence of two-tuples.
     * **headers** - *(optional)* Dictionary of HTTP headers to include when
     sending requests.
     * **cookies** - *(optional)* Dictionary of Cookie items to include when
@@ -1161,7 +1161,7 @@ class AsyncClient(BaseClient):
     * **auth** - *(optional)* An authentication class to use when sending
     requests.
     * **params** - *(optional)* Query parameters to include in request URLs, as
-    a string, dictionary, or list of two-tuples.
+    a string, dictionary, or sequence of two-tuples.
     * **headers** - *(optional)* Dictionary of HTTP headers to include when
     sending requests.
     * **cookies** - *(optional)* Dictionary of Cookie items to include when
diff --git a/httpx/_models.py b/httpx/_models.py
index a77f7a5790..2d11888254 100644
--- a/httpx/_models.py
+++ b/httpx/_models.py
@@ -441,7 +441,7 @@ def __init__(self, *args: QueryParamTypes, **kwargs: typing.Any) -> None:
             items = parse_qsl(value)
         elif isinstance(value, QueryParams):
             items = value.multi_items()
-        elif isinstance(value, list):
+        elif isinstance(value, (list, tuple)):
             items = value
         else:
             items = flatten_queryparams(value)
diff --git a/httpx/_types.py b/httpx/_types.py
index 776df1d8dc..7768bac11b 100644
--- a/httpx/_types.py
+++ b/httpx/_types.py
@@ -35,6 +35,7 @@
     "QueryParams",
     Mapping[str, Union[PrimitiveData, Sequence[PrimitiveData]]],
     List[Tuple[str, PrimitiveData]],
+    Tuple[Tuple[str, PrimitiveData], ...],
     str,
     bytes,
     None,
diff --git a/tests/models/test_queryparams.py b/tests/models/test_queryparams.py
index d591eded8c..7031a65cb9 100644
--- a/tests/models/test_queryparams.py
+++ b/tests/models/test_queryparams.py
@@ -9,6 +9,8 @@
         "a=123&a=456&b=789",
         {"a": ["123", "456"], "b": 789},
         {"a": ("123", "456"), "b": 789},
+        [("a", "123"), ("a", "456"), ("b", "789")],
+        (("a", "123"), ("a", "456"), ("b", "789")),
     ],
 )
 def test_queryparams(source):