diff --git a/ChangeLog.md b/ChangeLog.md
index edb119da2f2e7..0d670766c1364 100644
--- a/ChangeLog.md
+++ b/ChangeLog.md
@@ -23,6 +23,8 @@ See docs/process.md for more on how version tagging works.
 - Exporting `print`/`printErr` via `-sEXPORTED_RUNTIME_METHODS` is deprecated in
   favor of `out`/`err`.  The former symbols are supposed to be used with
   `-sINCOMING_MODULE_JS_API` instead. (#17955)
+- aio.h was removed from the sysroot.  Emscripten doesn't support any of the
+  functions in this header.
 
 3.1.24 - 10/11/22
 -----------------
diff --git a/system/lib/libc/musl/include/aio.h b/system/lib/libc/musl/include/aio.h
deleted file mode 100644
index 453c41b7489f3..0000000000000
--- a/system/lib/libc/musl/include/aio.h
+++ /dev/null
@@ -1,73 +0,0 @@
-#ifndef _AIO_H
-#define _AIO_H
-
-#ifdef __cplusplus
-extern "C" {
-#endif
-
-#include <features.h>
-#include <signal.h>
-#include <time.h>
-
-#define __NEED_ssize_t
-#define __NEED_off_t
-
-#include <bits/alltypes.h>
-
-struct aiocb {
-	int aio_fildes, aio_lio_opcode, aio_reqprio;
-	volatile void *aio_buf;
-	size_t aio_nbytes;
-	struct sigevent aio_sigevent;
-	void *__td;
-	int __lock[2];
-	volatile int __err;
-	ssize_t __ret;
-	off_t aio_offset;
-	void *__next, *__prev;
-	char __dummy4[32-2*sizeof(void *)];
-};
-
-#define AIO_CANCELED 0
-#define AIO_NOTCANCELED 1
-#define AIO_ALLDONE 2
-
-#define LIO_READ 0
-#define LIO_WRITE 1
-#define LIO_NOP 2
-
-#define LIO_WAIT 0
-#define LIO_NOWAIT 1
-
-int aio_read(struct aiocb *);
-int aio_write(struct aiocb *);
-int aio_error(const struct aiocb *);
-ssize_t aio_return(struct aiocb *);
-int aio_cancel(int, struct aiocb *);
-int aio_suspend(const struct aiocb *const [], int, const struct timespec *);
-int aio_fsync(int, struct aiocb *);
-
-int lio_listio(int, struct aiocb *__restrict const *__restrict, int, struct sigevent *__restrict);
-
-#if defined(_LARGEFILE64_SOURCE) || defined(_GNU_SOURCE)
-#define aiocb64 aiocb
-#define aio_read64 aio_read
-#define aio_write64 aio_write
-#define aio_error64 aio_error
-#define aio_return64 aio_return
-#define aio_cancel64 aio_cancel
-#define aio_suspend64 aio_suspend
-#define aio_fsync64 aio_fsync
-#define lio_listio64 lio_listio
-#define off64_t off_t
-#endif
-
-#if _REDIR_TIME64
-__REDIR(aio_suspend, __aio_suspend_time64);
-#endif
-
-#ifdef __cplusplus
-}
-#endif
-
-#endif
diff --git a/system/lib/update_musl.py b/system/lib/update_musl.py
index bd4bdc3cc1b1a..e2b826c2f94f2 100755
--- a/system/lib/update_musl.py
+++ b/system/lib/update_musl.py
@@ -35,6 +35,7 @@
   's390x', 'mips', 'mips64', 'mipsn32', 'powerpc', 'powerpc64',
   'm68k', 'microblaze', 'or1k')
 exclude_files = (
+  'aio.h',
   'sendfile.h',
   'auxv.h',
   'personality.h',