diff --git a/x-pack/plugins/security_solution/public/management/cypress/e2e/response_actions/response_console/isolate.cy.ts b/x-pack/plugins/security_solution/public/management/cypress/e2e/response_actions/response_console/isolate.cy.ts
index b08dcd0eea492..8b6ca1ed95e15 100644
--- a/x-pack/plugins/security_solution/public/management/cypress/e2e/response_actions/response_console/isolate.cy.ts
+++ b/x-pack/plugins/security_solution/public/management/cypress/e2e/response_actions/response_console/isolate.cy.ts
@@ -26,7 +26,8 @@ import { enableAllPolicyProtections } from '../../../tasks/endpoint_policy';
 import { createEndpointHost } from '../../../tasks/create_endpoint_host';
 import { deleteAllLoadedEndpointData } from '../../../tasks/delete_all_endpoint_data';
 
-describe('Response console', { tags: ['@ess', '@serverless'] }, () => {
+// FLAKY: https://github.com/elastic/kibana/issues/173464
+describe.skip('Response console', { tags: ['@ess', '@serverless'] }, () => {
   let indexedPolicy: IndexedFleetEndpointPolicyResponse;
   let policy: PolicyData;
   let createdHost: CreateAndEnrollEndpointHostResponse;