diff --git a/libbeat/cmd/platformcheck/platformcheck.go b/libbeat/cmd/platformcheck/platformcheck.go
new file mode 100644
index 00000000000..e3ccc50ad06
--- /dev/null
+++ b/libbeat/cmd/platformcheck/platformcheck.go
@@ -0,0 +1,48 @@
+// Licensed to Elasticsearch B.V. under one or more contributor
+// license agreements. See the NOTICE file distributed with
+// this work for additional information regarding copyright
+// ownership. Elasticsearch B.V. licenses this file to you under
+// the Apache License, Version 2.0 (the "License"); you may
+// not use this file except in compliance with the License.
+// You may obtain a copy of the License at
+//
+//     http://www.apache.org/licenses/LICENSE-2.0
+//
+// Unless required by applicable law or agreed to in writing,
+// software distributed under the License is distributed on an
+// "AS IS" BASIS, WITHOUT WARRANTIES OR CONDITIONS OF ANY
+// KIND, either express or implied.  See the License for the
+// specific language governing permissions and limitations
+// under the License.
+
+// +build linux windows
+
+package platformcheck
+
+import (
+	"fmt"
+	"math/bits"
+	"strings"
+
+	"github.com/shirou/gopsutil/host"
+)
+
+func CheckNativePlatformCompat() error {
+	const compiledArchBits = bits.UintSize // 32 if the binary was compiled for 32 bit architecture.
+
+	if compiledArchBits > 32 {
+		// We assume that 64bit binaries can only be run on 64bit systems
+		return nil
+	}
+
+	arch, err := host.KernelArch()
+	if err != nil {
+		return err
+	}
+
+	if strings.Contains(arch, "64") {
+		return fmt.Errorf("trying to run %vBit binary on 64Bit system", compiledArchBits)
+	}
+
+	return nil
+}
diff --git a/libbeat/cmd/platformcheck/platformcheck_other.go b/libbeat/cmd/platformcheck/platformcheck_other.go
new file mode 100644
index 00000000000..5ef8d3e8090
--- /dev/null
+++ b/libbeat/cmd/platformcheck/platformcheck_other.go
@@ -0,0 +1,24 @@
+// Licensed to Elasticsearch B.V. under one or more contributor
+// license agreements. See the NOTICE file distributed with
+// this work for additional information regarding copyright
+// ownership. Elasticsearch B.V. licenses this file to you under
+// the Apache License, Version 2.0 (the "License"); you may
+// not use this file except in compliance with the License.
+// You may obtain a copy of the License at
+//
+//     http://www.apache.org/licenses/LICENSE-2.0
+//
+// Unless required by applicable law or agreed to in writing,
+// software distributed under the License is distributed on an
+// "AS IS" BASIS, WITHOUT WARRANTIES OR CONDITIONS OF ANY
+// KIND, either express or implied.  See the License for the
+// specific language governing permissions and limitations
+// under the License.
+
+// +build !linux,!windows
+
+package platformcheck
+
+func CheckNativePlatformCompat() error {
+	return nil
+}
diff --git a/libbeat/cmd/platformcheck/platformcheck_test.go b/libbeat/cmd/platformcheck/platformcheck_test.go
new file mode 100644
index 00000000000..9e8d71b4f96
--- /dev/null
+++ b/libbeat/cmd/platformcheck/platformcheck_test.go
@@ -0,0 +1,65 @@
+// Licensed to Elasticsearch B.V. under one or more contributor
+// license agreements. See the NOTICE file distributed with
+// this work for additional information regarding copyright
+// ownership. Elasticsearch B.V. licenses this file to you under
+// the Apache License, Version 2.0 (the "License"); you may
+// not use this file except in compliance with the License.
+// You may obtain a copy of the License at
+//
+//     http://www.apache.org/licenses/LICENSE-2.0
+//
+// Unless required by applicable law or agreed to in writing,
+// software distributed under the License is distributed on an
+// "AS IS" BASIS, WITHOUT WARRANTIES OR CONDITIONS OF ANY
+// KIND, either express or implied.  See the License for the
+// specific language governing permissions and limitations
+// under the License.
+
+package platformcheck
+
+import (
+	"os"
+	"os/exec"
+	"path/filepath"
+	"runtime"
+	"testing"
+
+	"github.com/stretchr/testify/require"
+)
+
+func TestCheckPlatformCompat(t *testing.T) {
+	if !(runtime.GOARCH == "amd64" && (runtime.GOOS == "linux" ||
+		runtime.GOOS == "windows")) {
+		t.Skip("Test not support on current platform")
+	}
+
+	// compile test helper
+	tmp := t.TempDir()
+	helper := filepath.Join(tmp, "helper")
+
+	cmd := exec.Command("go", "test", "-c", "-o", helper)
+	cmd.Stdout = os.Stdout
+	cmd.Stderr = os.Stderr
+	cmd.Env = append(os.Environ(), "GOARCH=386")
+	require.NoError(t, cmd.Run(), "failed to compile test helper")
+
+	// run test helper
+	cmd = exec.Command(helper, "-test.v", "-test.run", "TestHelper")
+	cmd.Env = []string{"GO_USE_HELPER=1"}
+	output, err := cmd.Output()
+	if err != nil {
+		t.Logf("32bit binary tester failed.\n Output: %s", output)
+	}
+}
+
+func TestHelper(t *testing.T) {
+	if os.Getenv("GO_USE_HELPER") != "1" {
+		t.Log("ignore helper")
+		return
+	}
+
+	err := CheckNativePlatformCompat()
+	if err.Error() != "trying to run 32Bit binary on 64Bit system" {
+		t.Error("expected the native platform check to fail")
+	}
+}
diff --git a/libbeat/cmd/root.go b/libbeat/cmd/root.go
index 879da55004e..b35c71dde8d 100644
--- a/libbeat/cmd/root.go
+++ b/libbeat/cmd/root.go
@@ -28,6 +28,7 @@ import (
 	"github.com/elastic/beats/v7/libbeat/beat"
 	"github.com/elastic/beats/v7/libbeat/cfgfile"
 	"github.com/elastic/beats/v7/libbeat/cmd/instance"
+	"github.com/elastic/beats/v7/libbeat/cmd/platformcheck"
 )
 
 func init() {
@@ -56,6 +57,11 @@ type BeatsRootCmd struct {
 // run command, which will be called if no args are given (for backwards compatibility),
 // and beat settings
 func GenRootCmdWithSettings(beatCreator beat.Creator, settings instance.Settings) *BeatsRootCmd {
+	if err := platformcheck.CheckNativePlatformCompat(); err != nil {
+		fmt.Fprintf(os.Stderr, "Failed to initialize: %v\n", err)
+		os.Exit(1)
+	}
+
 	if settings.IndexPrefix == "" {
 		settings.IndexPrefix = settings.Name
 	}
diff --git a/x-pack/elastic-agent/CHANGELOG.next.asciidoc b/x-pack/elastic-agent/CHANGELOG.next.asciidoc
index 73028e9fac4..20cad963a5c 100644
--- a/x-pack/elastic-agent/CHANGELOG.next.asciidoc
+++ b/x-pack/elastic-agent/CHANGELOG.next.asciidoc
@@ -9,6 +9,7 @@
 
 - Docker container is not run as root by default. {pull}21213[21213]
 - Read Fleet connection information from `fleet.*` instead of `fleet.kibana.*`. {pull}24713[24713]
+- Beats build for 32Bit Windows or Linux system will refuse to run on a 64bit system. {pull}25186[25186]
 
 ==== Bugfixes
 - Fix rename *ConfigChange to *PolicyChange to align on changes in the UI. {pull}20779[20779]
diff --git a/x-pack/elastic-agent/main.go b/x-pack/elastic-agent/main.go
index f9bf84484ac..170a77811f0 100644
--- a/x-pack/elastic-agent/main.go
+++ b/x-pack/elastic-agent/main.go
@@ -10,11 +10,17 @@ import (
 	"os"
 	"time"
 
+	"github.com/elastic/beats/v7/libbeat/cmd/platformcheck"
 	"github.com/elastic/beats/v7/x-pack/elastic-agent/pkg/agent/cmd"
 )
 
 // Setups and Runs agent.
 func main() {
+	if err := platformcheck.CheckNativePlatformCompat(); err != nil {
+		fmt.Fprintf(os.Stderr, "Failed to initialize: %v\n", err)
+		os.Exit(1)
+	}
+
 	rand.Seed(time.Now().UnixNano())
 	command := cmd.NewCommand()
 	if err := command.Execute(); err != nil {